Humam Kadara, Ph.D.

Peer-Reviewed Articles

1. Casarrubios M, Cruz-Bermúdez A, Nadal E, Insa A, Garcia-Campelo R, Lázaro M, Dómine M, Majem M, Rodríguez-Abreu D, Martinez-Marti A, de Castro-Carpeño J, Cobo M, López-Vivanco G, Del Barco E, Bernabé Caro R, Viñolas N, Barneto Aranda I, Viteri S, Massuti B, Barquin M, Laza-Briviesca R, Sierra-Rodero B, Parra ER, Sanchez-Espiridion B, Rocha P, Kadara H, Wistuba II, Romero A, Calvo V, Provencio M. Pre-treatment tissue TCR repertoire evenness is associated with complete pathological response in patients with NSCLC receiving neoadjuvant chemoimmunotherapy. Clin Cancer Res. e-Pub 2021. PMID: 34376534.
2. Bazzi S, El-Darzi E, McDowell T, Modjtahedi H, Mudan S, Achkar M, Akle C, Kadara H, Bahr GM. Cytokine/Chemokine Release Patterns and Transcriptomic Profiles of LPS/IFNγ-Activated Human Macrophages Differentiated with Heat-Killed Mycobacterium obuense, M-CSF, or GM-CSF. Int J Mol Sci 22(13), 2021. e-Pub 2021. PMID: 34281268.
3. Stewart CA, Gay CM, Ramkumar K, Cargill KR, Cardnell RJ, Nilsson MB, Heeke S, Park EM, Kundu ST, Diao L, Wang Q, Shen L, Xi Y, Zhang B, Della Corte CM, Fan Y, Kundu K, Gao B, Avila K, Pickering CR, Johnson FM, Zhang J, Kadara H, Minna JD, Gibbons DL, Wang J, Heymach JV, Byers LA. Lung cancer models reveal SARS-CoV-2-induced EMT contributes to COVID-19 pathophysiology. J Thorac Oncol. e-Pub 2021. PMID: 34274504.
4. Sinjab A, Han G, Treekitkarnmongkol W, Hara K, Brennan PM, Dang M, Hao D, Wang R, Dai E, Dejima H, Zhang J, Bogatenkova E, Sanchez-Espiridion B, Chang K, Little DR, Bazzi S, Tran LM, Krysan K, Behrens C, Duose DY, Parra ER, Raso MG, Solis LM, Fukuoka J, Zhang J, Sepesi B, Cascone T, Byers LA, Gibbons DL, Chen J, Moghaddam SJ, Ostrin EJ, Rosen D, Heymach JV, Scheet P, Dubinett SM, Fujimoto J, Wistuba II, Stevenson CS, Spira A, Wang L, Kadara H. Resolving the spatial and cellular architecture of lung adenocarcinoma by multiregion single-cell sequencing. Cancer Discov. e-Pub 2021. PMID: 33972311.
5. Dejima H, Hu X, Chen R, Zhang J, Fujimoto J, Parra ER, Haymaker C, Hubert SM, Duose D, Solis LM, Su D, Fukuoka J, Tabata K, Pham HHN, Mcgranahan N, Zhang B, Ye J, Ying L, Little L, Gumbs C, Chow CW, Estecio MR, Godoy MCB, Antonoff MB, Sepesi B, Pass HI, Behrens C, Zhang J, Vaporciyan AA, Heymach JV, Scheet P, Lee JJ, Wu J, Futreal PA, Reuben A, Kadara H, Wistuba II, Zhang J. Immune evolution from preneoplasia to invasive lung adenocarcinomas and underlying molecular features. Nat Commun 12(1):2722, 2021. e-Pub 2021. PMID: 33976164.
6. Kadara H, Tran LM, Liu B, Vachani A, Li S, Sinjab A, Zhou XJ, Dubinett SM, Krysan K. Early Diagnosis and Screening for Lung Cancer. Cold Spring Harb Perspect Med. e-Pub 2021. PMID: 34001525.
7. Le X, Negrao MV, Reuben A, Federico L, Diao L, McGrail D, Nilsson M, Robichaux J, Munoz IG, Patel S, Elamin Y, Fan YH, Lee WC, Parra E, Solis Soto LM, Chen R, Li J, Karpinets T, Khairullah R, Kadara H, Behrens C, Sepesi B, Wang R, Zhu M, Wang L, Vaporciyan A, Roth J, Swisher S, Haymaker C, Zhang J, Wang J, Wong KK, Byers LA, Bernatchez C, Zhang J, Wistuba II, Gibbons DL, Akbay EA, Heymach JV. Characterization of the Immune Landscape of EGFR-Mutant NSCLC Identifies CD73/Adenosine Pathway as a Potential Therapeutic Target. J Thorac Oncol 16(4):583-600, 2021. e-Pub 2020. PMID: 33388477.
8. Cascone T, William WN, Weissferdt A, Leung CH, Lin HY, Pataer A, Godoy MCB, Carter BW, Federico L, Reuben A, Khan MAW, Dejima H, Francisco-Cruz A, Parra ER, Solis LM, Fujimoto J, Tran HT, Kalhor N, Fossella FV, Mott FE, Tsao AS, Blumenschein G, Le X, Zhang J, Skoulidis F, Kurie JM, Altan M, Lu C, Glisson BS, Byers LA, Elamin YY, Mehran RJ, Rice DC, Walsh GL, Hofstetter WL, Roth JA, Antonoff MB, Kadara H, Haymaker C, Bernatchez C, Ajami NJ, Jenq RR, Sharma P, Allison JP, Futreal A, Wargo JA, Wistuba II, Swisher SG, Lee JJ, Gibbons DL, Vaporciyan AA, Heymach JV, Sepesi B. Neoadjuvant nivolumab or nivolumab plus ipilimumab in operable non-small cell lung cancer: the phase 2 randomized NEOSTAR trial. Nat Med 27(3):504-514, 2021. e-Pub 2021. PMID: 33603241.
9. Han G, Sinjab A, Hara K, Treekitkarnmongkol W, Brennan P, Chang K, Bogatenkova E, Sanchez-Espiridion B, Behrens C, Solis LM, Gao B, Girard L, Zhang J, Sepesi B, Cascone T, Byers LA, Gibbons DL, Chen J, Moghaddam SJ, Ostrin EJ, Scheet P, Fujimoto J, Shay J, Heymach JV, Minna JD, Dubinett S, Wistuba II, Stevenson CS, Spira AE, Wang L, Kadara H. Single-Cell Expression Landscape of SARS-CoV-2 Receptor ACE2 and Host Proteases in Normal and Malignant Lung Tissues from Pulmonary Adenocarcinoma Patients. Cancers (Basel) 13(6), 2021. e-Pub 2021. PMID: 33809063.
10. Bahmad HF, Chalhoub RM, Harati H, Bou-Gharios J, Assi S, Ballout F, Monzer A, Msheik H, Araji T, Elajami MK, Ghanem P, Chamaa F, Kadara H, Abou-Antoun T, Daoud G, Fares Y, Abou-Kheir W. Tideglusib attenuates growth of neuroblastoma cancer stem/progenitor cells in vitro and in vivo by specifically targeting GSK-3β. Pharmacol Rep 73(1):211-226, 2021. e-Pub 2020. PMID: 33030673.
11. Treekitkarnmongkol W, Hassane M, Sinjab A, Chang K, Hara K, Rahal Z, Zhang J, Lu W, Sivakumar S, McDowell TL, Kantrowitz J, Zhou J, Lang W, Xu L, Ochieng JK, Nunomura-Nakamura S, Deng S, Behrens C, Raso MG, Fukuoka J, Reuben A, Ostrin EJ, Parra E, Solis LM, Spira AE, McAllister F, Cascone T, Wistuba II, Moghaddam SJ, Scheet PA, Fujimoto J, Kadara H. Augmented Lipocalin-2 is Associated with COPD and Counteracts Lung Adenocarcinoma Development. Am J Respir Crit Care Med 203(1):90-101, 2021. e-Pub 2020. PMID: 32730093.
12. Sinjab A, Daouk R, Abou-Kheir W, Kadara H. Whole Transcriptome Sequencing Analysis of Cancer Stem/Progenitor Cells Obtained from Mouse Lung Adenocarcinomas. Methods Mol Biol 2279:187-198, 2021. PMID: 33683695.
13. Rocha P, Salazar R, Zhang J, Ledesma D, Solorzano JL, Mino B, Villalobos P, Dejima H, Douse DY, Diao L, Mitchell KG, Le X, Zhang J, Weissferdt A, Parra-Cuentas E, Cascone T, Rice DC, Sepesi B, Kalhor N, Moran C, Vaporciyan A, Heymach J, Gibbons DL, Lee JJ, Kadara H, Wistuba I, Behrens C, Solis LM. CD73 expression defines immune, molecular, and clinicopathological subgroups of lung adenocarcinoma. Cancer Immunol Immunother. e-Pub 2021. PMID: 33416944.
14. Hu X, Estecio MR, Chen R, Reuben A, Wang L, Fujimoto J, Carrot-Zhang J, McGranahan N, Ying L, Fukuoka J, Chow CW, Pham HHN, Godoy MCB, Carter BW, Behrens C, Zhang J, Antonoff MB, Sepesi B, Lu Y, Pass HI, Kadara H, Scheet P, Vaporciyan AA, Heymach JV, Wistuba II, Lee JJ, Futreal PA, Su D, Issa JJ, Zhang J. Evolution of DNA methylome from precancerous lesions to invasive lung adenocarcinomas. Nat Commun 12(1):687, 2021. e-Pub 2021. PMID: 33514726.
15. Deng S, Ramos-Castaneda M, Velasco WV, Clowers MJ, Gutierrez BA, Noble O, Dong Y, Zarghooni M, Alvarado L, Caetano MS, Yang S, Ostrin EJ, Behrens C, Wistuba II, Stabile LP, Kadara H, Watowich SS, Moghaddam SJ. Interplay between estrogen and Stat3/NF-κB-driven immunomodulation in lung cancer. Carcinogenesis 41(11):1529-1542, 2020. PMID: 32603404.
16. Sinjab A, Han G, Wang L, Kadara H. Field Carcinogenesis in Cancer Evolution: What the Cell Is Going On?. Cancer Res 80(22):4888-4891, 2020. e-Pub 2020. PMID: 33023945.
17. Gaudreau PO, Negrao MV, Mitchell KG, Reuben A, Corsini EM, Li J, Karpinets T, Wang Q, Diao L, Wang J, Federico L, Parra-Cuentas ER, Khairullah R, Behrens C, Correa AM, Gomez D, Little L, Gumbs C, Kadara H, Fujimoto J, McGrail DJ, Vaporciyan AA, Swisher SG, Walsh G, Antonoff MB, Weissferdt A, Tran H, Roarty E, Haymaker C, Bernatchez C, Zhang J, Futreal PA, Wistuba II, Cascone T, Heymach JV, Sepesi B, Zhang J, Gibbons DL. Neoadjuvant Chemotherapy Increases Cytotoxic T cell, Tissue Resident Memory T cell and B Cell Infiltration in Resectable Non-Small Cell Lung Cancer. J Thorac Oncol. e-Pub 2020. PMID: 33096269.
18. Mitchell KG, Amini B, Wang Y, Carter BW, Godoy MCB, Parra ER, Behrens C, Villalobos P, Reuben A, Lee JJ, Weissferdt A, Moran CA, Fujimoto J, Sepesi B, Walsh GL, Vaporciyan AA, Hofstetter WL, William WN, Gibbons DL, Wang J, Hwu P, Swisher SG, Piwnica-Worms D, Kadara H, Wistuba II, Heymach JV, Peng W, Cascone T. 18F-fluorodeoxyglucose positron emission tomography correlates with tumor immunometabolic phenotypes in resected lung cancer. Cancer Immunol Immunother 69(8):1519-1534, 2020. e-Pub 2020. PMID: 32300858.
19. Habli Z, AlChamaa W, Saab R, Kadara H, Khraiche ML. Circulating Tumor Cell Detection Technologies and Clinical Utility: Challenges and Opportunities. Cancers (Basel) 12(7), 2020. e-Pub 2020. PMID: 32708837.
20. Al Matari N, Deeb G, Mshiek H, Sinjab A, Kadara H, Abou-Kheir W, Mhanna R. Anti-Tumor Effects of Biomimetic Sulfated Glycosaminoglycans on Lung Adenocarcinoma Cells in 2D and 3D In Vitro Models. Molecules 25(11), 2020. e-Pub 2020. PMID: 32503108.
21. Behrens C, Rocha P, Parra ER, Feng L, Rodriguez-Canales J, Solis LM, Mino B, Zhang J, Gibbons DL, Sepesi B, Rice D, Heymach JV, Moran C, Creighton CJ, Lee JJ, Kadara H, Wistuba II. Female Gender Predicts Augmented Immune Infiltration in Lung Adenocarcinoma. Clin Lung Cancer. e-Pub 2020. PMID: 32763065.
22. Stewart CA, Gay CM, Ramkumar K, Cargill KR, Cardnell RJ, Nilsson MB, Heeke S, Park EM, Kundu ST, Diao L, Wang Q, Shen L, Xi Y, Maria Della Corte C, Fan Y, Kundu K, Pickering CR, Johnson FM, Zhang J, Kadara H, Minna JD, Gibbons DL, Wang J, Heymach JV, Byers LA. SARS-CoV-2 infection induces EMT-like molecular changes, including ZEB1-mediated repression of the viral receptor ACE2, in lung cancer models. bioRxiv, 2020. e-Pub 2020. PMID: 32577652.
23. Saab S, Zalzale H, Rahal Z, Khalifeh Y, Sinjab A, Kadara H. Insights Into Lung Cancer Immune-Based Biology, Prevention, and Treatment. Front Immunol 11:159, 2020. e-Pub 2020. PMID: 32117295.
24. Daouk R, Bahmad HF, Saleh E, Monzer A, Ballout F, Kadara H, Abou-Kheir W. Genome-wide gene expression analysis of a murine model of prostate cancer progression: Deciphering the roles of IL-6 and p38 MAPK as potential therapeutic targets. PLoS One 15(8):e0237442, 2020. e-Pub 2020. PMID: 32790767.
25. Makoukji J, El-Sitt S, Makhoul NJ, Soueid J, Kadara H, Boustany RM. Sex differences in gene expression with galactosylceramide treatment in Cln3?ex7/8 mice. PLoS One 15(10):e0239537, 2020. e-Pub 2020. PMID: 33006978.
26. Reuben A, Zhang J, Chiou SH, Gittelman RM, Li J, Lee WC, Fujimoto J, Behrens C, Liu X, Wang F, Quek K, Wang C, Kheradmand F, Chen R, Chow CW, Lin H, Bernatchez C, Jalali A, Hu X, Wu CJ, Eterovic AK, Parra ER, Yusko E, Emerson R, Benzeno S, Vignali M, Wu X, Ye Y, Little LD, Gumbs C, Mao X, Song X, Tippen S, Thornton RL, Cascone T, Snyder A, Wargo JA, Herbst R, Swisher S, Kadara H, Moran C, Kalhor N, Zhang J, Scheet P, Vaporciyan AA, Sepesi B, Gibbons DL, Robins H, Hwu P, Heymach JV, Sharma P, Allison JP, Baladandayuthapani V, Lee JJ, Davis MM, Wistuba II, Futreal PA, Zhang J. Comprehensive T cell repertoire characterization of non-small cell lung cancer. Nat Commun 11(1):603, 2020. e-Pub 2020. PMID: 32001676.
27. Jakubek YA, Chang K, Sivakumar S, Yu Y, Giordano MR, Fowler J, Huff CD, Kadara H, Vilar E, Scheet P. Large-scale analysis of acquired chromosomal alterations in non-tumor samples from patients with cancer. Nat Biotechnol. e-Pub 2019. PMID: 31685958.
28. Shi B, Behrens C, Vaghani V, Riquelme EM, Rodriguez-Canales J, Kadara H, Lin H, Lee J, Liu H, Wistuba I, Simon G. Oncogenic enhancer of zeste homolog 2 is an actionable target in patients with non-small cell lung cancer. Cancer Med 8(14):6383-6392, 2019. e-Pub 2019. PMID: 31456359.
29. Kudo Y, Haymaker C, Zhang J, Reuben A, Duose DY, Fujimoto J, Roy-Chowdhuri S, Solis Soto LM, Dejima H, Parra ER, Mino B, Abraham R, Ikeda N, Vaporcyan A, Gibbons D, Zhang J, Lang FF, Luthra R, Lee JJ, Moran C, Huse JT, Kadara H, Wistuba II. Suppressed immune microenvironment and repertoire in brain metastases from patients with resected non-small-cell lung cancer. Ann Oncol 30(9):1521-1530, 2019. PMID: 31282941.
30. Kadara H, Sivakumar S, Jakubek Y, San Lucas FA, Lang W, McDowell T, Weber Z, Behrens C, Davies GE, Kalhor N, Moran C, El-Zein R, Mehran R, Swisher SG, Wang J, Zhang J, Fujimoto J, Fowler J, Heymach JV, Dubinett S, Spira AE, Ehli EA, Wistuba II, Scheet P. Driver Mutations in Normal Airway Epithelium Elucidate Spatiotemporal Resolution of Lung Cancer. Am J Respir Crit Care Med 200(6):742-750, 2019. PMID: 30896962.
31. Hu X, Fujimoto J, Ying L, Fukuoka J, Ashizawa K, Sun W, Reuben A, Chow CW, McGranahan N, Chen R, Hu J, Godoy MC, Tabata K, Kuroda K, Shi L, Li J, Behrens C, Parra ER, Little LD, Gumbs C, Mao X, Song X, Tippen S, Thornton RL, Kadara H, Scheet P, Roarty E, Ostrin EJ, Wang X, Carter BW, Antonoff MB, Zhang J, Vaporciyan AA, Pass H, Swisher SG, Heymach JV, Lee JJ, Wistuba II, Hong WK, Futreal PA, Su D, Zhang J. Multi-region exome sequencing reveals genomic evolution from preneoplasia to lung adenocarcinoma. Nat Commun 10(1):2978, 2019. e-Pub 2019. PMID: 31278276.
32. Khoueiry P, Fakhri G, Akel R, El Assaad M, Mahfouz R, Khuri F, Chami H, Petersen J, Viet S, Davies G, Kadara H, Tfayli A. Deep targeted sequencing analysis of hot spot mutations in non-small cell lung cancer patients from the Middle Eastern population. J Thorac Dis 11(6):2383-2391, 2019. PMID: 31372275.
33. Sivakumar S, San Lucas FA, Jakubek YA, McDowell TL, Lang W, Kallsen N, Peyton S, Davies GE, Fukuoka J, Yatabe Y, Zhang J, Futreal PA, Fowler J, Fujimoto J, Ehli EA, Hawk ET, Wistuba II, Kadara H, Scheet P. Genomic landscape of allelic imbalance in premalignant atypical adenomatous hyperplasias of the lung. EBioMedicine 42:296-303, 2019. e-Pub 2019. PMID: 30905849.
34. Nehme E, Rahal Z, Sinjab A, Khalil A, Chami H, Nemer G, Kadara H. Epigenetic Suppression of the T-box Subfamily 2 (TBX2) in Human Non-Small Cell Lung Cancer. Int J Mol Sci 20(5), 2019. e-Pub 2019. PMID: 30866410.
35. Daouk R, Hassane M, Bahmad HF, Sinjab A, Fujimoto J, Abou-Kheir W, Kadara H. Genome-Wide and Phenotypic Evaluation of Stem Cell Progenitors Derived From Gprc5a-Deficient Murine Lung Adenocarcinoma With Somatic Kras Mutations. Front Oncol 9:207, 2019. e-Pub 2019. PMID: 31001473.
36. Caetano MS, Hassane M, Van HT, Bugarin E, Cumpian AM, McDowell CL, Cavazos CG, Zhang H, Deng S, Diao L, Wang J, Evans SE, Behrens C, Wistuba II, Fuqua SAW, Lin H, Stabile LP, Watowich SS, Kadara H, Moghaddam SJ. Sex specific function of epithelial STAT3 signaling in pathogenesis of K-ras mutant lung cancer. Nat Commun 9(1):4589, 2018. e-Pub 2018. PMID: 30389925.
37. Bauer AK, Umer M, Richardson VL, Cumpian AM, Harder AQ, Khosravi N, Azzegagh Z, Hara NM, Ehre C, Mohebnasab M, Caetano MS, Merrick DT, van Bokhoven A, Wistuba II, Kadara H, Dickey BF, Velmurugan K, Mann PR, Lu X, Barón AE, Evans CM, Moghaddam SJ. Requirement for MUC5AC in KRAS-dependent lung carcinogenesis. JCI Insight 3(15). e-Pub 2018. PMID: 30089720.
38. Khosravi N, Caetano MS, Cumpian AM, Unver N, De la Garza Ramos C, Noble O, Daliri S, Hernandez BJ, Gutierrez BA, Evans SE, Hanash S, Alekseev AM, Yang Y, Chang SH, Nurieva R, Kadara H, Chen J, Ostrin EJ, Moghaddam SJ. IL22 Promotes Kras-Mutant Lung Cancer by Induction of a Protumor Immune Response and Protection of Stemness Properties. Cancer Immunol Res 6(7):788-797, 2018. e-Pub 2018. PMID: 29764837.
39. Kantrowitz J, Sinjab A, Xu L, McDowell TL, Sivakumar S, Lang W, Nunomura-Nakamura S, Fukuoka J, Nemer G, Darwiche N, Chami H, Tfayli A, Wistuba II, Scheet P, Fujimoto J, Spira AE, Kadara H. Genome-Wide Gene Expression Changes in the Normal-Appearing Airway during the Evolution of Smoking-Associated Lung Adenocarcinoma. Cancer Prev Res (Phila) 11(4):237-248, 2018. e-Pub 2018. PMID: 29382653.
40. Kadara H, Choi M, Zhang J, Parra ER, Rodriguez-Canales J, Gaffney SG, Zhao Z, Behrens C, Fujimoto J, Chow C, Yoo Y, Kalhor N, Moran C, Rimm D, Swisher S, Gibbons DL, Heymach J, Kaftan E, Townsend JP, Lynch TJ, Schlessinger J, Lee J, Lifton RP, Wistuba II, Herbst RS. Whole-exome sequencing and immune profiling of early-stage lung adenocarcinoma with fully annotated clinical follow-up. Ann Oncol 29(4):1072, 2018. PMID: 29688333.
41. Bergqvist C, Kadara H, Hamie L, Nemer G, Safi R, Karouni M, Marrouche N, Abbas O, Hasbani DJ, Kibbi AG, Nassar D, Shimomura Y, Kurban M. SLURP-1 is mutated in Mal de Meleda, a potential molecular signature for melanoma and a putative squamous lineage tumor suppressor gene. Int J Dermatol 57(2):162-170, 2018. e-Pub 2017. PMID: 29231248.
42. Khalil A, Dekmak B, Boulos F, Kantrowitz J, Spira A, Fujimoto J, Kadara H, El-Hachem N, Nemer G. Transcriptomic Alterations in Lung Adenocarcinoma Unveil New Mechanisms Targeted by the TBX2 Subfamily of Tumor Suppressor Genes. Front Oncol 8:482, 2018. e-Pub 2018. PMID: 30425966.
43. Deshpande A, Lang W, McDowell T, Sivakumar S, Zhang J, Wang J, San Lucas FA, Fowler J, Kadara H, Scheet P. Strategies for identification of somatic variants using the Ion Torrent deep targeted sequencing platform. BMC Bioinformatics 19(1):5, 2018. e-Pub 2018. PMID: 29301485.
44. Gleber-Netto FO, Zhao M, Trivedi S, Wang J, Jasser S, McDowell C, Kadara H, Zhang J, Wang J, William WN, Lee JJ, Nguyen ML, Pai SI, Walline HM, Shin DM, Ferris RL, Carey TE, Myers JN, Pickering CR, Head and Neck Cancer Specialized Program of Research Excellence (SPORE) Human Immunodeficiency Virus (HIV) Supplement Consortium. Distinct pattern of TP53 mutations in human immunodeficiency virus-related head and neck squamous cell carcinoma. Cancer 124(1):84-94, 2018. e-Pub 2017. PMID: 29053175.
45. Abdel-Samad R, Aouad P, Gali-Muhtasib H, Sweidan Z, Hmadi R, Kadara H, D'Andrea EL, Fucci A, Pisano C, Darwiche N. Mechanism of action of the atypical retinoid ST1926 in colorectal cancer: DNA damage and DNA polymerase α. Am J Cancer Res 8(1):39-55, 2018. e-Pub 2018. PMID: 29416919.
46. Rahal Z, Abdulhai F, Kadara H, Saab R. Genomics of adult and pediatric solid tumors. Am J Cancer Res 8(8):1356-1386, 2018. e-Pub 2018. PMID: 30210910.
47. Nassar FJ, Talhouk R, Zgheib NK, Tfayli A, El Sabban M, El Saghir NS, Boulos F, Jabbour MN, Chalala C, Boustany RM, Kadara H, Zhang Z, Zheng Y, Joyce B, Hou L, Bazarbachi A, Calin G, Nasr R. microRNA Expression in Ethnic Specific Early Stage Breast Cancer: an Integration and Comparative Analysis. Sci Rep 7(1):16829, 2017. e-Pub 2017. PMID: 29203780.
48. Kadara H, Nemer G, Safi R, Rebeiz N, Daou L, Delbani D, Btadini W, Abbas O, Tofaili M, Bitar F, Kibbi AG, Shimomura Y, Kurban M. Erythropoietic protoporphyria a clinical and molecular study from Lebanon: Ferrochelatase a potential tumor suppressor gene in colon cancer. Clin Genet 92(5):495-502, 2017. e-Pub 2017. PMID: 28075030.
49. Sivakumar S, Lucas FAS, McDowell TL, Lang W, Xu L, Fujimoto J, Zhang J, Futreal PA, Fukuoka J, Yatabe Y, Dubinett SM, Spira AE, Fowler J, Hawk ET, Wistuba II, Scheet P, Kadara H. Genomic Landscape of Atypical Adenomatous Hyperplasia Reveals Divergent Modes to Lung Adenocarcinoma. Cancer Res 77(22):6119-6130, 2017. e-Pub 2017. PMID: 28951454.
50. Fujimoto J, Nunomura-Nakamura S, Liu Y, Lang W, McDowell T, Jakubek Y, Ezzeddine D, Kapere Ochieng J, Petersen J, Davies G, Fukuoka J, Wistuba II, Ehli E, Fowler J, Scheet P, Kadara H. Development of Kras mutant lung adenocarcinoma in mice with knockout of the airway lineage-specific gene Gprc5a. Int J Cancer 141(8):1589-1599, 2017. e-Pub 2017. PMID: 28653505.
51. Cascone T, Xu L, Lin HY, Liu W, Tran HT, Liu Y, Howells K, Haddad V, Hanrahan E, Nilsson MB, Cortez MA, Giri U, Kadara H, Saigal B, Park YY, Peng W, Lee JS, Ryan AJ, Jüergensmeier JM, Herbst RS, Wang J, Langley RR, Wistuba II, Lee JJ, Heymach JV. The HGF/c-MET Pathway Is a Driver and Biomarker of VEGFR-inhibitor Resistance and Vascular Remodeling in Non-Small Cell Lung Cancer. Clin Cancer Res 23(18):5489-5501, 2017. e-Pub 2017. PMID: 28559461.
52. Khalil AA, Sivakumar S, Lucas FAS, McDowell T, Lang W, Tabata K, Fujimoto J, Yatabe Y, Spira A, Scheet P, Nemer G, Kadara H. TBX2 subfamily suppression in lung cancer pathogenesis: a high-potential marker for early detection. Oncotarget 8(40):68230-68241, 2017. e-Pub 2017. PMID: 28978111.
53. Kadara H, Choi M, Zhang J, Parra ER, Rodriguez-Canales J, Gaffney SG, Zhao Z, Behrens C, Fujimoto J, Chow C, Yoo Y, Kalhor N, Moran C, Rimm D, Swisher S, Gibbons DL, Heymach J, Kaftan E, Townsend JP, Lynch TJ, Schlessinger J, Lee J, Lifton RP, Wistuba II, Herbst RS. Whole-exome sequencing and immune profiling of early-stage lung adenocarcinoma with fully annotated clinical follow-up. Ann Oncol 28(1):75-82, 2017. PMID: 27687306.
54. Choi M, Kadara H, Zhang J, Parra ER, Rodriguez-Canales J, Gaffney SG, Zhao Z, Behrens C, Fujimoto J, Chow C, Kim K, Kalhor N, Moran C, Rimm D, Swisher S, Gibbons DL, Heymach J, Kaftan E, Townsend JP, Lynch TJ, Schlessinger J, Lee J, Lifton RP, Herbst RS, Wistuba II. Mutation profiles in early-stage lung squamous cell carcinoma with clinical follow-up and correlation with markers of immune function. Ann Oncol 28(1):83-89, 2017. PMID: 28177435.
55. Rahal Z, El Nemr S, Sinjab A, Chami H, Tfayli A, Kadara H. Smoking and Lung Cancer: A Geo-Regional Perspective. Front Oncol 7:194, 2017. e-Pub 2017. PMID: 28920053.
56. Bazzi S, El-Darzi E, McDowell T, Modjtahedi H, Mudan S, Achkar M, Akle C, Kadara H, Bahr GM. Defining Genome-Wide Expression and Phenotypic Contextual Cues in Macrophages Generated by Granulocyte/Macrophage Colony-Stimulating Factor, Macrophage Colony-Stimulating Factor, and Heat-Killed Mycobacteria. Front Immunol 8:1253, 2017. e-Pub 2017. PMID: 29046677.
57. Parra ER, Behrens C, Rodriguez-Canales J, Lin H, Mino B, Blando J, Zhang J, Gibbons DL, Heymach JV, Sepesi B, Swisher SG, Weissferdt A, Kalhor N, Izzo J, Kadara H, Moran C, Lee JJ, Wistuba II. Image Analysis-based Assessment of PD-L1 and Tumor-Associated Immune Cells Density Supports Distinct Intratumoral Microenvironment Groups in Non-small Cell Lung Carcinoma Patients. Clin Cancer Res 22(24):6278-6289, 2016. e-Pub 2016. PMID: 27252415.
58. Kadara H, Scheet P, Wistuba II, Spira AE. Early Events in the Molecular Pathogenesis of Lung Cancer. Cancer Prev Res (Phila) 9(7):518-27, 2016. e-Pub 2016. PMID: 27006378.
59. Jakubek Y, Lang W, Vattathil S, Garcia M, Xu L, Huang L, Yoo SY, Shen L, Lu W, Chow CW, Weber Z, Davies G, Huang J, Behrens C, Kalhor N, Moran C, Fujimoto J, Mehran R, El-Zein R, Swisher SG, Wang J, Fowler J, Spira AE, Ehli EA, Wistuba II, Scheet P, Kadara H. Genomic Landscape Established by Allelic Imbalance in the Cancerization Field of a Normal Appearing Airway. Cancer Res 76(13):3676-83, 2016. e-Pub 2016. PMID: 27216194.
60. Caetano MS, Zhang H, Cumpian AM, Gong L, Unver N, Ostrin EJ, Daliri S, Chang SH, Ochoa CE, Hanash S, Behrens C, Wistuba II, Sternberg C, Kadara H, Ferreira CG, Watowich SS, Moghaddam SJ. IL6 Blockade Reprograms the Lung Tumor Microenvironment to Limit the Development and Progression of K-ras-Mutant Lung Cancer. Cancer Res 76(11):3189-99, 2016. e-Pub 2016. PMID: 27197187.
61. Koneru B, Shi Y, Munaweera I, Wight-Carter M, Kadara H, Yuan H, Di Pasqua AJ, Balkus KJ. Radiotherapeutic bandage for the treatment of squamous cell carcinoma of the skin. Nucl Med Biol 43(6):333-8, 2016. e-Pub 2016. PMID: 27260774.
62. Peng S, Sen B, Mazumdar T, Byers LA, Diao L, Wang J, Tong P, Giri U, Heymach JV, Kadara HN, Johnson FM. Dasatinib induces DNA damage and activates DNA repair pathways leading to senescence in non-small cell lung cancer cell lines with kinase-inactivating BRAF mutations. Oncotarget 7(1):565-79, 2016. e-Pub 2015. PMID: 26623721.
63. Maki Y, Fujimoto J, Lang W, Xu L, Behrens C, Wistuba II, Kadara H. LAPTM4B is associated with poor prognosis in NSCLC and promotes the NRF2-mediated stress response pathway in lung cancer cells. Sci Rep 5:13846, 2015. e-Pub 2015. PMID: 26343532.
64. Skoulidis F, Byers LA, Diao L, Papadimitrakopoulou VA, Tong P, Izzo J, Behrens C, Kadara H, Parra ER, Canales JR, Zhang J, Giri U, Gudikote J, Cortez MA, Yang C, Fan Y, Peyton M, Girard L, Coombes KR, Toniatti C, Heffernan TP, Choi M, Frampton GM, Miller V, Weinstein JN, Herbst RS, Wong KK, Zhang J, Sharma P, Mills GB, Hong WK, Minna JD, Allison JP, Futreal A, Wang J, Wistuba II, Heymach JV. Co-occurring genomic alterations define major subsets of KRAS-mutant lung adenocarcinoma with distinct biology, immune profiles, and therapeutic vulnerabilities. Cancer Discov 5(8):860-77, 2015. e-Pub 2015. PMID: 26069186.
65. Gold KA, Kim ES, Liu DD, Yuan P, Behrens C, Solis LM, Kadara H, Rice DC, Wistuba II, Swisher SG, Hofstetter WL, Lee JJ, Hong WK. Prediction of survival in resected non-small cell lung cancer using a protein-expression based risk model: Implications for personalized chemoprevention and therapy. Clin Cancer Res 20(7):1946-54, 2014. e-Pub 2013. PMID: 24366692.
66. Kadara H, Fujimoto J, Yoo SY, Maki Y, Gower AC, Kabbout M, Garcia MM, Chow CW, Chu Z, Mendoza G, Shen L, Kalhor N, Hong WK, Moran C, Wang J, Spira A, Coombes KR, Wistuba II. Transcriptomic Architecture of the Adjacent Airway Field Cancerization in Non-Small Cell Lung Cancer. J Natl Cancer Inst 106(3):dju004, 2014. e-Pub 2014. PMID: 24563515.
67. Behrens C, Solis LM, Lin H, Yuan P, Tang X, Kadara H, Riquelme E, Galindo H, Moran CA, Kalhor N, Swisher SG, Simon GR, Stewart DJ, Lee JJ, Wistuba II. EZH2 Protein Expression Associates with the Early Pathogenesis, Tumor Progression, and Prognosis of Non-Small Cell Lung Carcinoma. Clin Cancer Res 19(23):6556-65, 2013. e-Pub 2013. PMID: 24097870.
68. Kabbout M, Garcia MM, Fujimoto J, Liu DD, Woods D, Chow CW, Mendoza G, Momin AA, James BP, Solis L, Behrens C, Lee JJ, Wistuba II, Kadara H. ETS2 mediated tumor suppressive function and MET oncogene inhibition in human non-small cell lung cancer. Clin Cancer Res 19(13):3383-95, 2013. e-Pub 2013. PMID: 23659968.
69. Kadara H, Shen L, Fujimoto J, Saintigny P, Chow CW, Lang W, Chu Z, Garcia M, Kabbout M, Fan YH, Behrens C, Liu DA, Mao L, Lee JJ, Gold KA, Wang J, Coombes KR, Kim ES, Hong WK, Wistuba II. Characterizing the molecular spatial and temporal field of injury in early-stage smoker non-small cell lung cancer patients after definitive surgery by expression profiling. Cancer Prev Res (Phila) 6(1):8-17, 2013. e-Pub 2012. PMID: 23087048.
70. Fujimoto J, Kadara H, Garcia MM, Kabbout M, Behrens C, Liu DD, Lee JJ, Solis LM, Kim ES, Kalhor N, Moran C, Sharafkhaneh A, Lotan R, Wistuba II. G-protein coupled receptor family C, group 5, member A (GPRC5A) expression is decreased in the adjacent field and normal bronchial epithelia of patients with chronic obstructive pulmonary disease and non-small-cell lung cancer. J Thorac Oncol 7(12):1747-54, 2012. PMID: 23154545.
71. Solis LM, Behrens C, Raso MG, Lin HY, Kadara H, Yuan P, Galindo H, Tang X, Lee JJ, Kalhor N, Wistuba II, Moran CA. Histologic patterns and molecular characteristics of lung adenocarcinoma associated with clinical outcome. Cancer 118(11):2889-99, 2012. e-Pub 2011. PMID: 22020674.
72. Kadara H, Wistuba II. Field cancerization in non-small cell lung cancer: implications in disease pathogenesis. Proc Am Thorac Soc 9(2):38-42, 2012. PMID: 22550239.
73. Nunez MI, Behrens C, Woods DM, Lin H, Suraokar M, Kadara H, Hofstetter W, Kalhor N, Lee JJ, Franklin W, Stewart DJ, Wistuba II. High expression of folate receptor alpha in lung cancer correlates with adenocarcinoma histology and EGFR [corrected] mutation. J Thorac Oncol 7(5):833-40, 2012. PMID: 22729036.
74. Kadara H, Kabbout M, Wistuba II. Pulmonary adenocarcinoma: a renewed entity in 2011. Respirology 17(1):50-65, 2012. e-Pub 2011. PMID: 22040022.
75. Tang X, Kadara H, Behrens C, Liu DD, Xiao Y, Rice D, Gazdar AF, Fujimoto J, Moran C, Varella-Garcia M, Lee JJ, Hong WK, Wistuba II. Abnormalities of the TITF-1 lineage-specific oncogene in NSCLC: Implications in lung cancer pathogenesis and prognosis. Clin Cancer Res 17(8):2434-43, 2011. e-Pub 2011. PMID: 21257719.
76. Cascone T, Herynk MH, Xu L, Du Z, Kadara H, Nilsson MB, Oborn CJ, Park YY, Erez B, Jacoby JJ, Lee JS, Lin HY, Ciardiello F, Herbst RS, Langley RR, Heymach JV. Upregulated stromal EGFR and vascular remodeling in mouse xenograft models of angiogenesis inhibitor-resistant human lung adenocarcinoma. J Clin Invest 121(4):1313-28, 2011. e-Pub 2011. PMID: 21436589.
77. Kadara H, Behrens C, Yuan P, Solis L, Liu D, Gu X, Minna JD, Lee JJ, Kim E, Hong WK, Wistuba II, Lotan R. A five-gene and corresponding-protein signature for stage-I lung adenocarcinoma prognosis. Clin Cancer Res 17(6):1490-501, 2011. e-Pub 2010. PMID: 21163870.
78. Chen Y, Deng J, Fujimoto J, Kadara H, Men T, Lotan D, Lotan R. Gprc5a deletion enhances the transformed phenotype in normal and malignant lung epithelial cells by eliciting persistent Stat3 signaling induced by autocrine leukemia inhibitory factor. Cancer Res 70(21):8917-26, 2010. e-Pub 2010. PMID: 20959490.
79. Fujimoto J, Kadara H, Men T, van Pelt C, Lotan D, Lotan R. Comparative functional genomics analysis of NNK tobacco-carcinogen induced lung adenocarcinoma development in Gprc5a-knockout mice. PLoS One 5(7):e11847, 2010. e-Pub 2010. PMID: 20686609.
80. Kadara H, Fujimoto J, Men T, Ye X, Lotan D, Lee JS, Lotan R. A Gprc5a tumor suppressor loss of expression signature is conserved, prevalent, and associated with survival in human lung adenocarcinomas. Neoplasia 12(6):499-505, 2010. PMID: 20563252.
81. Deng J, Fujimoto J, Ye XF, Men TY, Van Pelt CS, Chen YL, Lin XF, Kadara H, Tao Q, Lotan D, Lotan R. Knockout of the tumor suppressor gene Gprc5a in mice leads to NF-kappaB activation in airway epithelium and promotes lung inflammation and tumorigenesis. Cancer Prev Res (Phila) 3(4):424-37, 2010. e-Pub 2010. PMID: 20354164.
82. Chakravarti N, Kadara H, Yoon DJ, Shay JW, Myers JN, Lotan D, Sonenberg N, Lotan R. Differential inhibition of protein translation machinery by curcumin in normal, immortalized, and malignant oral epithelial cells. Cancer Prev Res (Phila) 3(3):331-8, 2010. e-Pub 2010. PMID: 20145189.
83. Yuan P, Kadara H, Behrens C, Tang X, Woods D, Solis LM, Huang J, Spinola M, Dong W, Yin G, Fujimoto J, Kim E, Xie Y, Girard L, Moran C, Hong WK, Minna JD, Wistuba II. Sex determining region Y-Box 2 (SOX2) is a potential cell-lineage gene highly expressed in the pathogenesis of squamous cell carcinomas of the lung. PLoS One 5(2):e9112, 2010. e-Pub 2010. PMID: 20161759.
84. Behrens C, Feng L, Kadara H, Kim HJ, Lee JJ, Mehran R, Hong WK, Lotan R, Wistuba II. Expression of interleukin-1 receptor-associated kinase-1 in non-small cell lung carcinoma and preneoplastic lesions. Clin Cancer Res 16(1):34-44, 2010. e-Pub 2009. PMID: 20028769.
85. Kadara H, Lacroix L, Behrens C, Solis L, Gu X, Lee JJ, Tahara E, Lotan D, Hong WK, Wistuba II, Lotan R. Identification of gene signatures and molecular markers for human lung cancer prognosis using an in vitro lung carcinogenesis system. Cancer Prev Res (Phila) 2(8):702-11, 2009. e-Pub 2009. PMID: 19638491.
86. Tahara E, Kadara H, Lacroix L, Lotan D, Lotan R. Activation of protein kinase C by phorbol 12-myristate 13-acetate suppresses the growth of lung cancer cells through KLF6 induction. Cancer Biol Ther 8(9):801-7, 2009. e-Pub 2009. PMID: 19333010.
87. Kadara H, Tahara E, Kim HJ, Lotan D, Myers J, Lotan R. Involvement of Rac in fenretinide-induced apoptosis. Cancer Res 68(11):4416-23, 2008. PMID: 18519704.
88. Pathak AK, Bhutani M, Nair AS, Ahn KS, Chakraborty A, Kadara H, Guha S, Sethi G, Aggarwal BB. Ursolic acid inhibits STAT3 activation pathway leading to suppression of proliferation and chemosensitization of human multiple myeloma cells. Mol Cancer Res 5(9):943-55, 2007. PMID: 17855663.
89. Kadara H, Lacroix L, Lotan D, Lotan R. Induction of endoplasmic reticulum stress by the pro-apoptotic retinoid N-(4-hydroxyphenyl)retinamide via a reactive oxygen species-dependent mechanism in human head and neck cancer cells. Cancer Biol Ther 6(5):705-11, 2007. e-Pub 2007. PMID: 17404501.
90. Schroeder CP, Kadara H, Lotan D, Woo JK, Lee HY, Hong WK, Lotan R. Involvement of mitochondrial and Akt signaling pathways in augmented apoptosis induced by a combination of low doses of celecoxib and N-(4-hydroxyphenyl) retinamide in premalignant human bronchial epithelial cells. Cancer Res 66(19):9762-70, 2006. PMID: 17018636.
91. Kadara H, Schroeder CP, Lotan D, Pisano C, Lotan R. Induction of GDF-15/NAG-1/MIC-1 in human lung carcinoma cells by retinoid-related molecules and assessment of its role in apoptosis. Cancer Biol Ther 5(5):518-22, 2006. e-Pub 2006. PMID: 16582595.
92. Darwiche N, Hatoum A, Dbaibo G, Kadara H, Nasr R, Abou-Lteif G, Bazzi R, Hermine O, de Thé H, Bazarbachi A. N-(4-hydroxyphenyl)retinamide induces growth arrest and apoptosis in HTLV-I-transformed cells. Leukemia 18(3):607-15, 2004. PMID: 14712289.

Invited Articles

1. Kadara H, Kabbout M, Wistuba II. Pulmonary adenocarcinoma: a renewed entity in 2011. Respirology 17(1):50-65, 2012.
2. Kadara H, Wistuba II,. Field cancerization in NSCLC: implications in disease pathogenesis. Proceedings of the American Thoracic Society 9(2):38-42, 2012.
3. Kadara H. Reuben Lotan, Ph.D. (1946-2011): in memoriam. Cancer Biol Ther 12(12):1015-7, 2011. e-Pub 2011. PMID: 22236874.

Abstracts

1. Smruthy Sivakumar, Yasminka Jakubek, Francis Anthony San Lucas, Wenhua Lang, Tina McDowell, Zachary Weber, Carmen Behrens, Neda Kalhor, Cesar Moran, Randa El-Zein, Gareth Davies, Junya Fujimoto, Reza Mehran, Stephen Swisher, Jing Wang, Jerry Fowler, Stephen Dubinett, Avrum Spira, Erik Ehli, Ignacio Wistuba, Paul Scheet, Humam Kadara. Somatic mutational processes in the cancerization field of the normal-appearing airway reveal early drivers in the development of non-small cell lung cancer. American Association for Cancer Research (AACR) Annual Meeting April 2018, Chicago, Illinois, USA, 2018.
2. Yasminka Jakubek, Francis Anthony San Lucas, Smruthy Sivakumar, Jerry Fowler, Humam Kadara, Paul Scheet.. Landscape of allelic imbalance in pan-cancer adjacent normal tissue: Insights into field cancerization and cancer pathogenesis. American Association for Cancer Research (AACR) Annual Meeting April 2018, Chicago, Illinois, USA, 2018.
3. Chen R, Fujimoto J, Reuben A, Ying L, Hu X, Chow CW, Canales J, Sun W, Hu J, Parra E, Behrens C, Wu CJ, Little L, Gumbs C, Wiesnoski D, Han G, Lee WC, Scheet P, Kadara H, Antonoff M, Vaporciyan AA, Wisher S, Zhang J, Heymach J, Hong WK, Wistuba II, Futreal A, Su D, Zhang J.. T-cell repertoire evolution from the normal lung to invasive lung adenocarcinoma. American Association for Cancer Research (AACR) Annual Meeting April 2018, Chicago, Illinois, USA, 2018.
4. Athar Khalil, Junya Fujimoto, Tina McDowell, Paul Scheet, Georges Nemer, Humam Kadara.. Early suppression of the TBX2 subfamily of transcription factors during in vivo tobacco carcinogen-mediated lung adenocarcinoma development. American Association for Cancer Research (AACR) Annual Meeting April 2018, Chicago, Illinois, USA, 2018.
5. Athar Khalil, Nehme El-Hachem, Batoul Dekmak, Humam Kadara, Georges Nemer. Role of the evolutionarily conserved TBX2 subfamily of transcription factors in the molecular pathogenesis of human lung adenocarcinoma. American Association for Cancer Research (AACR) Annual Meeting April 2018, Chicago, Illinois, USA, 2018.
6. Smruthy Sivakumar, Yasminka Jakubek, Wenhua Lang, Tina McDowell, Melinda M. Garcia, Chi-Wan Chow, Zachary Weber, Carmen Behrens, Neda Kalhor, Cesar Moran, Randa El-Zein, Gareth Davies, Junya Fujimoto, Reza Mehran, Stephen G. Swisher, Jing Wang, Avrum E. Spira, Jerry Fowler, F Anthony San Lucas, Ignacio I. Wistuba, Erik Ehli, Paul Scheet, Humam Kadara. Mutational landscape in the normal-appearing airway cancerization field of early-stage non-small cell lung cancer. American Association for Cancer Research (AACR) Annual Meeting April 2017, Washington, D.C., USA, 2017.
7. Joshua Kapere Ochieng, Wenhua Lang, Sayuri Nunomura-Nakamura, Tina McDowell, Ralph Arlinghaus, Yuki Imaoka, Takashui Hori, Junya Fukuoka, Paul Scheet, Junya Fujimoto, Humam Kadara. Loss of Lcn2 promotes development of smoking-associated KRAS mutant lung cancer. American Association for Cancer Research (AACR) Annual Meeting April 2017, Washington, D.C., USA, 2017.
8. Yasminka A. Jakubek, Smruthy Sivakumar, Louise C. Strong, Humam Kadara, Paul Scheet. Intratumoral divergence of copy number alterations in NSCLC. American Association for Cancer Research (AACR) Annual Meeting April 2017, Washington, D.C., USA, 2017.
9. Jerry Fowler, F. Anthony San Lucas, Smruthy Sivakumar, Aditya Deshpande, Humam Kadara, Paul Scheet. Optimizing the replication of cancer genomics workflows: case studies. American Association for Cancer Research (AACR) Annual Meeting April 2017, Washington, D.C., USA, 2017.
10. Mauricio S. Caetano, Hieu Van, Emmanuel Bugarin, Amber Cumpian, Tina McDowell, Huiyuan Zhang, Scott E. Evans, Stephanie Watowich, Humam Kadara, Seyed J. Moghaddam. Gender specific function of epithelial IL-6-STAT3 pathway in KRAS mutant lung cancer. American Association for Cancer Research (AACR) Annual Meeting April 2017, Washington, D.C., USA, 2017.
11. Misha Umer, Amer M. Cumpian, Nasim Khosravi, Zoulikha Azzegagh, Maede Mohebnasab, Mauricio S. Caetano, Edwin J. Ostrin, Ignacio I. Wistuba, Burton Dickey, Humam Kadara, Christopher M. Evans, Seyed J. Moghaddam. MUC5AC plays an essential role in promotion of KRAS mutant lung cancer. American Association for Cancer Research (AACR) Annual Meeting April 2017, Washington, D.C., USA, 2017.
12. Sahil Seth, Won-Chul Lee, Jianhua Zhang, Junya Fujimoto, Carmen Behrens, Tina McDowell, Neda Kalhor, Annikka Weissferdt, Vali Papadimitrakopoulou, John Heymach, Don Gibbons, P. Andy Futreal, Ignacio Wistuba, Cesar Moran, Humam Kadara, Jianjun Zhang. Genomic and transcriptomic profiling of localized sarcomatoid carcinoma of the lung reveals association between immune activation and a lower risk of recurrence. Annual ASCO meeting, June 2017. Chicago, Illinois, USA, 2017.
13. Anne S. Tsao, Ignacio Wistuba, Dianren Xia, Lauren Byers, Lixia Diao, Jing Wang, Vassiliki Papadimitrakopoulou, Ximing Tang, Wei Lu, Humam Kadara, Fred de Sauvage, Dimitry Grigoryev, Zeynep H. Gumus, Zhi Tan, Shuxing Zhang, Monique Nilsson, John V. Heymach. Germline and somatic smoothened (SMO) mutations in non-small cell lung cancer (NSCLC) are potentially responsive to hedgehog inhibitor vismodegib. Annual ASCO meeting, June 2017. Chicago, Illinois, USA, 2017.
14. Ferdinandos Skoulidis, Yasir Elamin, Vassiliki Papadimitrakopoulou, Pan Tong, Jing Wang, Jeff Lewis, Waree Rinsurongkawong, Caleb Chu, Emily Roarty, Jianjun Zhang, Hai Tran, Jaime Rodriguez-Canales, Edwin Parra, Carmen Behrens, Humam Kadara, Ignacio Ivan Wistuba, John Heymach. Impact of Major Co-Mutations on the Immune Contexture and Response of KRAS-Mutant Lung Adenocarcinoma to Immunotherapy. IASLC annual meeting December 2016, Vienna, Austria, 2016.
15. Junya Fujimoto, Sayuri Nunomura, Wenhua Lang, Yihua Liu, Jinsong Wei, Joshua Ochieng, Yasminka Jakubek, Edwin Ostrin, Jason Petersen, Gareth Davies, Nadine Darwiche, Erik Ehli, Jerry Fowler, Paul Scheet, Humam Kadara. Development of Kras mutant lung adenocarcinoma in tobacco carcinogen exposed mice with knockout of the airway lineage-specific G-protein coupled receptor Gprc5a. American Association for Cancer Research (AACR) Annual Meeting April 2016, New Orleans, LA, USA, 2016.
16. Joshua Ochieng, Sayuri Nunomura, Wenhua Lang, Jinsong Wei, Li Xu, Christina McDowell, Edwin Ostrin, Ralph Arlinghaus, Junya Fujimoto, Humam Kadara. Expression of the lipocalin 2 oncogene in the development of smoking-associated and Kras mutant lung adenocarcinoma. American Association for Cancer Research (AACR) Annual Meeting April 2016, New Orleans, LA, US, 2016.
17. Humam Kadara, Murim Choi, Jiexin Zhang, Edwin Parra, Jaime Rodriguez-Canales, Stephen G. Gaffney, Zi-ming Zhao, Carmen Behrens, Junya Fujimoto, Chi-Wan Chow, Neda Kalhor, Cesar Moran, David Rimm, Stephen Swisher, Don L. Gibbons, John V. Heymach, Edward Kaftan, Jeffrey P. Townsend, Thomas J. Lynch, Joseph Schlessinger, J. Jack Lee, Richard Lifton, Roy S. Herbst, Ignacio I. Wistuba. Whole-exome sequencing and immune profiling of early-stage lung adenocarcinoma. American Association for Cancer Research (AACR) Annual Meeting April 2016, New Orleans, LA, USA, 2016.
18. Murim Choi, Humam Kadara, Jiexin Zhang, Edwin Parra, Jaime Rodriguez-Canales, Stephen G. Gaffney, Zi-ming Zhao, Carmen Behrens, Junya Fujimoto, Chi-Wan Chow, Neda Kalhor, Cesar Moran, David Rimm, Stephen Swisher, don L. Gibbons, John V. Heymach, Edward Kaftan, Jeffrey P. Townsend, Thomas J. Lynch, Joseph Schlessinger, J. Jack Lee, Richard Lifton, Roy S. Herbst, Ignacio I. Wistuba. Mutation and immune profiles in early-stage lung squamous cell carcinoma. American Association for Cancer Research (AACR) Annual Meeting April 2016, New Orleans, LA, USA, 2016.
19. Edwin Parra, Pan Tong, Humam Kadara, Vassiliki Papadimitrakopoulou, Julie Izzo, Jaime Rodriguez-Canales, Carmen Behrens, John D. Minna, Jing Wang, Ignacio I. Wistuba, John V. Heymach, Ferdinandos Skoulidis. Impact of APOBEC mutagenesis on the immune microenvironment of lung adenocarcinoma (LUAC). American Association for Cancer Research (AACR) Annual Meeting April 2016, New Orleans, LA, USA, 2016.
20. Paul Scheet, Yasminka Jakubek, Wenhua Lang, Selina Vattahil, Melinda Garcia, Lili Huang, Wei Lu, Chi-Wan chow, Zachary Weber, Gareth E. Davies, Carmen Behrens, Neda Kalhor, Cesar Moran, Junya Fujimoto, Reza J. Mehran, Jerry Fowler, Erik A. Ehli, Ignacio I. Wistuba, Humam Kadara.. The genomic landscape of allelic imbalance in the normal-appearing airway field of cancerization. 2015 Innovations in Cancer Prevention and Research Institute of Texas Conference, 2015.
21. Ferdinandos Skoulidis, Lauren Byers, Lixia Diao, Vassiliki Papadimitrakopolou, Pan Tong, Julie Izzo, Carmen Behrens, Humam Kadara, Edwin R. Parra, Jaime Rodriguez-Canales, Jianjun Zhang, Uma Giri, Jayanthi Gudikote, Maria Angelica Cortez, Chao Yang, You Hong Fan, Michael Peyton, Luc Girard, Kevin R. Coombes, Carlo Toniatti, Timothy P. Heffernan, Murim Choi, Garrett M. Frampton, Vincent Miller, John N. Weinstein, Roy S. Herbst, Kwok-Kin Wong, Jianhua Zhang, Padmanee Sharma, Gordon M. Mills, Waun Ki Hong, John D. Minna, James P. Allison, Andrew Futreal, Jing Wang, Ignacio I. Wistuba, John V. Heymach.. Co-occuring genomic alterations define major subsets of KRAS-mutant lung adenocarcinoma (LUAC) with distinct biology and therapeutic vulnerabilities. American Association for Cancer Research (AACR) Annual Meeting April 2015, Philadelphia, PA, USA, 2015.
22. Mauricio S. Caetano, Amber M. Cumpian, Lei Gong, Seon H. Chang, Huiyan Zhang, Humam Kadara, Cinthya Sternberg, Carlos G. Ferreira, Stephanie S. Watowich, Seyed J. Moghaddam.. Targeting IL-6 as a preventive and therapeutic strategy for K-ras mutant lung cancer. American Association for Cancer Research (AACR) Annual Meeting April 2015, Philadelphia, PA, USA, 2015.
23. Ferdinandos Skoulidis, Warren Denning, Lixia Diao, Pan Tong, You Hong Fan, Vassiliki Papadimitrakopoulou, Julie Izzo, Carmen Behrens, Humam Kadara, Edwin Roger Parra Cuentas, Jaime Rodriguez, Jing Wang, Don Lynn Gibbons, Lauren Averett Byers, Ignacio Ivan Wistuba, John Heymach.. Association of inactivation of STK11/LKB1 with a suppressive immune microenvironment in lung adenocarcinoma (LUAC). American Society for Clinical Oncology (ASCO) Annual Meeting June 2015, Chicago, IL, USA, 2015.
24. Edwin R. Parra, Carmen Behrens, Jaime Rodriguez-Canales, Heather Lin, Barbara Mino, Jorge Blando, Yanyan Lou, Don L. Gibbons, John V. Heymach, Stephen G. Swisher, Annikka Weissferdt, Neda Kahlor, Julie Izzo, J. Jack Lee, Humam Kadara, Cesar Moran, Ignacio I. Wistuba.. High programmed cell death ligand 1 expression and low immune infiltrate score correlate with worse outcome in patients with lung adenocarcinoma. American Association for Cancer Research (AACR) Annual Meeting April 2015, Philadelphia, PA, USA, 2015.
25. Yasminka Jakubek, Wenhua Lang, Selina Vattahil, Melinda Garcia, Lili Huang, Wei Lu, Chi-Wan chow, Zachary Weber, Gareth E. Davies, Carmen Behrens, Neda Kalhor, Cesar Moran, Junya Fujimoto, Reza J. Mehran, Jerry Fowler, Erik A. Ehli, Ignacio I. Wistuba, Paul Scheet, Humam Kadara. The landscape of allelic imbalance in the normal-appearing airway field of cancerization. American Association for Cancer Research (AACR) Annual Meeting April 2015, Philadelphia, PA, USA, 2015.
26. Ferdinandos Skoulidis, Warren Denning, Lixia Diao, Pan Tong, You Hong Fan, Vassiliki Papadimitrakopoulou, Julie Izzo, Carmen Behrens, Humam Kadara, Edwin Roger Parra Cuentas, Jaime Rodriguez-Canales, Jing Wang, Lauren Averett Byers, Ignacio Ivan Wistuba, John Heymach. Impact of co-mutations on the immune microenvironment of KRAS-mutant lung adenocarcinoma. IASLC annual meeting 2015, 2015.
27. Maki Y, Fujimoto J, Yoo SY, Garcia MM, Gower A, Shen L, Chow CW, Behrens C, Kalhor N, Moran C, Wang J, Spira A, Coombes KR, Wistuba I, Kadara H. Transcriptomic architecture of the field of cancerization in the adjacent normal-appearing airway: Early mechanisms in lung carcinogenesis. American Association for Cancer Research (AACR) Annual Meeting April 2014, San Diego, CA, USA, 2014.
28. Junya Fujimoto, Jiexin Zhang, Curtis Pickering, Humam Kadara, Donna Muzny, Anika Weissfedrt, David A. Wheeler, Jeffrey Myers, Jing Wang, Ignacio Wistuba, Neda Kalhor, Cesar Moran.. Identification of novel somatic variants in thymic epithelial tumors by next-generation sequencing. United States & Canadian Academy of Pathology (USCAP) Annual Meeting MArch 2014, San Diego, CA, USA, 2014.
29. Banibrata Sen, Shaohua Peng, Tuhina Mazumdar, Lauren A. Byers, Humam Kadara, Faye M. Johnson.. The multitargeted kinase inhibitor dasatinib induces DNA damage, Hippo pathway engagement and senescence in lung cancer cell lines that possess kinase-inactivating BRAF mutations. . American Association for Cancer Research (AACR) Annual Meeting April 2014, San Diego, CA, USA, 2014.
30. Rebecca Kusko, Christina Anderlind, Gerald Wang, Sherry Zhang, W. Dean Wallace, Tonya Wasler, Michael Ebright, Melinda M. Garcia, Rosana Eisenberg, Gina Lee, Gang Liu, David Elashoff, Neda Kalhor, Cesar Moran, Rexa Mehran, Junya Fujimoto, Pierre P. Massion, Steven Dubinett, Ignacio Wistuba, Marc Lendburg, Humam Kadara, Avrum Spira.. Mapping the airway-wide molecular field of injury in smokers with lung cancer. American Association for Cancer Research (AACR) Annual Meeting April 2014, San Diego, CA, USA, 2014.
31. Rebecca Kusko, Carly Garrison, Teresa Wang, Josh Campbell, Joseph Perez-Rogers, Lingqi Luo, Jennifer Beane, Gang Liu, Humam Kadara, Steve Belinsky, Marc Lendburg, Avrum Spira.. Gene and miRNA expression networks specific to never smoker lung adenocarcinoma. American Association for Cancer Research (AACR) Annual Meeting April 2014, San Diego, CA, USA, 2014.
32. Junya Fujimoto, Humam Kadara, Ignacio Wistuba. Challenges to investigate lung carcinogenesis at the University of Texas MD Anderson Cancer Center Thoracic Molecular Pathology Laboratory. 18th Congress of the Asian Pacific Society of Respirology, 2013.
33. Yuho Maki, Junya Fujimoto, Suk-Young Yoo, Adam Gower, Li Shen, Melinda M. Garcia, Mohamed Kabbout, Chi-Wan Chow, Waun Ki Hong, Neda Kalhor, Jing Wang, Cesar Moran, Avrum Spira, Kevin R. Coombes, Ignacio I. Wistuba, Humam Kadara.. Transcriptomic architecture of the airway field cancerization in early-stage non-small cell lung cancer. American Association for Cancer Research (AACR) Annual Meeting April 2013, Washington, D.C., USA, 2013.
34. Humam Kadara, Junya Fujimoto, Suk-Young Yoo, Melinda Garcia, Mohamed Kabbout, Annette Basey, Jing Wang, Kevin R. Coombes, Edward S Kim, Waun Ki Hong, Neda Kalhor, Cesar Moran and Ignacio I. Wistuba.. Gene expression profiling of lung tumors and matched normal airways reveals common and disparate aberrant pathways in squamous cell carcinoma and adenocarcinoma development and potential targets for chemoprevention in early stage lung cancer patients. American Association for Cancer Research (AACR) Annual Meeting April 2012, Chicago, Illinois, USA, 2012.
35. Mohamed Kabbout, Melinda Garcia, Junya Fujimoto, Chi-Wan Chow, Denise Woods, Patricia Koch, Amin Momin, Brian P James, Luisa M.Solis, Carmen Behrens, Ignacio Wistuba and Humam Kadara.. Tumor suppressor effects of ETS2 transcriptional factor in human non-small cell lung cancer pathogenesis. American Association for Cancer Research (AACR) Annual Meeting April 2012, Chicago, Illinois, USA, 2012.
36. Junya Fujimoto, Humam Kadara, Junya Fukuoka, Keisuke Aoe, Nobukazu Fujimoto, Takumi Kushimoto, Kouki Inai, Kenzo Hiroshima, Milind Suraokar, Anne Tsao, Reza Mehran, Ignacio I. Wistuba.. Expression patterns of the G-protein coupled-receptor, GPRC5A, in human malignant pleural mesothelioma. American Association for Cancer Research (AACR) Annual Meeting April 2012, Chicago, Illinois, USA, 2012.
37. Fujimoto J, Kadara H, Woo SK, Melinda Garcia M, Kabbout M, Basey A, Wang J, Coombes KR, Kim ES, Hong WK, Kalhor N, Moran C, Wistuba II.. Gene expression profiling of lung field cancerization reveals potential targets for chemoprevention. Annual Meeting of the Japanese Society of Pathology April 2012, Japan, 2012.
38. Erick Riquelme, Carmen Behrens, Milind Suraokar, Chi-Wan Chow, Humam Kadara, Ignacio I. Wistuba, Luc Girard, John D. Minna.. EZH2High and miR-101Low expressions are associated with chemoresistance and shorter survival in patients with lung adenocarcinoma who received adjuvant therapy. American Association for Cancer Research (AACR) Annual Meeting April 2012, Chicago, Illinois, USA, 2012.
39. Carmen Behrens, Luisa Solis, Heather Lin, Ximing Tang, Ping Yuan, Humam Kadara, Erick Riquelme, Hector Galindo, Waun Ki Hong, J. Jack Lee, Ignacio I. Wistuba.. Analysis of EZH2 and TITF-1 protein expression identifies a subset of lung adenocarcinomas with better prognosis. American Association for Cancer Research (AACR) Annual Meeting April 2012, Chicago, Illinois, USA, 2012.
40. Fujimoto J, Suraokar M, Fukuoka J, Aoe K, Kadara H, Behrens C, Hori T, Fujimoto N, Kishimoto T, Inai K, Hiroshima K, Mehran R, Tsao A, Wistuba II.. The University of Texas MD Anderson Cancer Center Mesothelioma Program. The 53rd Annual Meeting of the Japan Lung Cancer Society, 2012.
41. Carmen Behrens, Ping Yuan, Luisa Solis, Pierre Saintigny, Humam Kadara, Junya Fujimoto, Cesar Moran, Stephen G. Swisher, John V. Heymach, Ignacio I. Wistuba.. EZH2 expression is an early event in the pathogenesis of non-small cell lung cancer (NSCLC) and correlates with tumor progression. American Association for Cancer Research (AACR) Annual Meeting April 2012, Orlando, FL, USA, 2011.
42. Junya Fujimoto, Humam Kadara, Carmen Behrens, Diane Liu, J. Jack Lee, Luisa M. Solis, Edward Kim, Amir Sharafkhaneh, Ignacio I. Wistuba, Lotan Reuben.. Implication of GPRC5A loss in lung carcinogenesis in patients with and without chronic obstructive pulmonary disease. American Association for Cancer Research (AACR) Annual Meeting April 2011, Orlando, FL, USA, 2011.
43. Humam Kadara, Pierre Saintigny, Youhong Fan, Chi-Wan Chow, ZuoMing Chu, Wenhua Lang, Carmen Behrens, Kathryn Gold, Diane Liu, J. Jack Lee, Li Mao, Edward S. Kim, Waun K. Hong, Ignacio I. Wistuba. Gene expression analysis of field of cancerization in early stage NSCLC patients towards development of biomarkers for personalized prevention. American Association for Cancer Research (AACR) Annual Meeting April 2011, Orlando, FL, USA, 2011.
44. Junya Fujimoto, Humam Kadara, Carmen Behrens, Diane Liu, J. Jack Lee, Junya Fukuoka, Luisa M Solis, Edward S Kim, Arif Shalafkhane, Ignacio I Wistuba, Reuben Lotan.. The G-protein coupled receptor family C group 5 member A loss is implicated in lung carcinogenesis. Japanese Society of Pathology Annual Meeting April 2011, Japan, 2011.
45. Humam Kadara, Pierre Saintigny, Li Shen, Chi-Wan Chow, ZuoMing Chu, Wenhua Lang, Mohamed Kabbout, Youhong Fan, Carmen Behrens, Kathryn Gold, Diane Liu, J. Jack Lee, Li Mao, Jing Wang, Kevin R. Coombes, Edward Kim, Waun Ki Hong, Ignacio I. Wistuba.. Field of cancerization molecular profiling in early stage NSCLC patients towards development of biomarkers for personalized prevention. World Conference on Lung Cancer (WCLC) July 2011, Amsterdam, Netherlands, 2011.
46. Ignacio I. Wistuba, Humam Kadara, Edward S. Kim and Waun Ki Hong. Molecular Pathology of Lung Cancer & Intermediate Markers of Carcinogenesis. World Conference on Lung Cancer (WCLC) July 2011, Amsterdam, Netherlands, 2011.
47. Humam Kadara, Waun K. Hong, Ignacio I. Wistuba, Reuben Lotan.. A five-gene signature predictive of survival in lung adenocarcinoma but not in squamous cell carcinoma. American Association for Cancer Research (AACR) Annual Meeting April 2010, Washington, D.C., USA, 2010.
48. Humam Kadara, Carmen Behrens, Luisa Solis, John D. Minna, Waun-Ki Hong, Ignacio I. Wistuba and Reuben Lotan.. A five-gene signature predictive of survival in early stage lung adenocarcinoma but not in squamous cell carcinoma. Joint IASLC-AACR conference on the molecular origins of lung cancer January 2010, San Coronado, CA, USA, 2010.
49. Yulong Chen, Jiong Deng, Junya Fujimoto, Humam Kadara, Xiaofeng Ye, Taoyan Men, Dafna Lotan, Reuben Lotan.. Loss of the lung-specific tumor suppressor Gprc5a causes persistent activation of Stat3 leading to increased survival signaling in normal and malignant lung epithelial cells. American Association for Cancer Research (AACR) Annual Meeting April 2010, Washington, D.C., USA, 2010.
50. Tina Cascone, Matthew H. Herynk, Li Xu, Humam Kadara, Emer Hanrahan, You-Hong Fan, Babita Siagal, Yun-Yong Park, Ju-Seog Lee, Robert R. Langley, Juliane M. Jurgensmeier, Anderson Ryan, John V. Heymach.. Increased HGF is associated with resistance to VEGFR tyrosine kinase inhibitors (TKIs) in non-small cell lung cancer (NSCLC). American Association for Cancer Research (AACR) Annual Meeting April 2010, Washington, D.C., USA, 2010.
51. Junya Fujimoto, Humam Kadara, Qingguo Tao, Taoyan Men, Carolyn van Pelt, Dafna Lotan, Reuben Lotan.. Tobacco carcinogen-enhanced lung tumorigenesis in Gprc5a knockout mice recapitulates human lung cancer development. American Association for Cancer Research (AACR) Annual Meeting April 2010, Washington, D.C., USA, 2010.
52. Ping Yuan, Humam Kadara, Carmen Behrens, Ximing Tang, Denise Woods, Luisa M. Solis, Jiaoti Huang, Monica Spinola, Wenli Dong, Guosheng Yin, Junya Fujimoto, Edward Kim, Yang Xie, Luc Girard, Cesar Moran, Waun Ki Hong, John D. Minna, Ignacio I. Wistuba.. Sex determining region Y-box 2 (SOX2) is a potential cell-lineage gene highly expressed in the pathogenesis of squamous cell carcinomas of the lung. American Association for Cancer Research (AACR) Annual Meeting April 2010, Washington, D.C., USA, 2010.
53. Humam Kadara, Junya Fujimoto, Taoyan Men, Xiaofeng Ye, Dafna Lotan, Ju-Seog Lee, Reuben Lotan.. A murine loss of lung tumor suppressor gene signature predicts poor survival in human NSCLC. IASLC 9th Annual Targeted Therapies of the Treatment of Lung Cancer Meeting February 2009, Santa Monica, CA, USA, 2009.
54. Tina Cascone, Matthew H. Herynk, Danny Du, Carol J. Oborn, Humam Kadara, Monique Nilsson, Ju-Seog Lee, Robert R. Langley, John V. Heymach.. A role for stromal EGFR activation in resistance to VEGF blockade in human non-small cell lung cancer (NSCLC) xenograft models. American Association for Cancer Research (AACR) Annual Meeting April 2009, Denver, CO, USA, 2009.
55. Humam Kadara, Ludovic Lacroix, Carmen Behrens, Luisa Solis, Xuemin Gu, J. Jack Lee, Eiji Tahara, Waun K. Hong, Ignacio I. Wistuba, Reuben Lotan.. Identification of prognostic markers by integrative gene expression analysis of an in vitro model of lung carcinogenesis and their validation in lung cancer tissue specimens. American Association for Cancer Research (AACR) Annual Meeting April 2009, Denver, CO, USA, 2009.
56. Humam Kadara, Junya Fujimoto, Taoyan Men, Dafna Lotan, Xiaofeng Ye, Ju-Seog Lee, Reuben Lotan.. Gene expression signatures of tumor suppressor Gprc5a loss in murine lung cells predict poor survival in human lung adenocarcinomas. American Association for Cancer Research (AACR) Annual Meeting April 2009, Denver, CO, USA, 2009.
57. Cascone T, Herynk M, Du D, Kadara H, Hanrahan EO, Nilsson MB, Lin HY. Lee JJ, Park YY, Lee JS, Heymach JV.. Stromal HGF and VEGFR-1 are associated with acquired resistance to VEGFR tyrosine kinase inhibitors in non-small cell lung cancer (NSCLC). World Conference on Lung Cancer (WCLC) August 2009, San Francisco, CA, USA, 2009.
58. Humam Kadara, Hyun-Jung Kim, Eiji Tahara, Dafna Lotan, and Reuben Lotan.. Differential effects of 4HPR on gene expression and apoptosis in normal and malignant cells of the head and neck despite induction of reactive oxygen species in both cell types. American Association for Cancer Research (AACR) Annual Meeting April 2008, San Diego, CA, USA, 2008.
59. Humam Kadara, Ju-Seog Lee, Xiaofeng Ye, Taoyan Men, Dafna Lotan, and Reuben Lotan.. Murine loss of tumor suppressor Gprc5a gene expression signatures are associated with poor prognosis in human lung adenocarcinomas. University of Texas MD Anderson Cancer Center 61st Annual symposium in Cancer Research Systems Biology of Cancer November 2008, Houston, TX, USA, 2008.
60. Ludovic Lacroix, Eiji Tahara, Carmen Behrens, Humam Kadara, Dafna Lotan, Ignacio I. Wistuba, Reuben Lotan. Identification of biomarkers for human lung carcinogenesis by analysis of transcriptomes of cell lines representing different stages of lung carcinogenesis. American Association for Cancer Research (AACR) Annual Meeting April 2008, Los Angeles, CA, USA, 2007.
61. Nitin Chakravarti, Humam Kadara, Ludovic Lacroix, Do-Jun Yoon, Jerry W. Shay, Jeffrey Myers, Dafna Lotan, Reuben Lotan.. Inhibition of cell Growth in head and neck premalignant cells by curcumin in an eIF4E-dependent manner. American Association for Cancer Research (AACR) Annual Meeting April 2008, Los Angeles, CA, USA, 2007.
62. Eiji Tahara, Humam Kadara, Ludovic Lacroix, Dafna Lotan, Reuben Lotan.. Inhibition of lung cancer cell growth by the putative tumor suppressor gene KLF6 through activation of Protein kinase C alpha and inhibition of the PI3kinase pathway. American Association for Cancer Research (AACR) Annual Meeting April 2008, Los Angeles, CA, USA, 2007.
63. Humam Kadara, Eiji Tahara, Hyun-Jung Kim, Dafna Lotan, Jeffrey Myers, Reuben Lotan.. Differential Rac-mediated generation of reactive oxygen species increases sensitivity of metastatic cancer cells to the proapoptotic synthetic retinoid 4HPR relative to their primary cancer cell counterparts. American Association for Cancer Research (AACR) Annual Meeting April 2008, Los Angeles, CA, USA, 2007.
64. Humam Kadara, Jeffrey Myers, Reuben Lotan. Implication of Rac-mediated Generation of Reactive Oxygen Species in Enhanced Sensitivity of Metastatic Head and Neck Cancer Cells to Induction of Apoptosis by the Synthetic Retinoid 4HPR Relative to their Corresponding Primary Cancer Cells. 15th SPORE Investigators’ Workshop July 2007, Baltimore, MD, USA, 2007.
65. Humam Kadara, Ludovic Lacroix, Dafna Lotan and Reuben Lotan.. The pro-apoptotic retinoid N-(4-hydroxyphenyl)retinamide activates the endoplasmic reticulum stress pathway in 22B human head and neck cancer cells. American Association for Cancer Research (AACR) Annual Meeting April 2006, Washington, D.C., USA, 2006.
66. Reuben Lotan, Hyun-Jun Kim, Nitin Chakravarti, Ludovic Lacroix, Dafna Lotan, and Humam Kadara. Pivotal role of reactive oxygen species and MAP kinases in induction of cell death pathways by the synthetic retinoid fenretinide. 14th SPORE Investigators’ Workshop July 2006, Baltimore, MD, USA, 2006.
67. Claudia Schroeder, Humam Kadara, and Reuben Lotan.. Combination of Celecoxib and 4HPR exhibits enhanced apoptosis by increasing mitochondrial membrane permeability and suppressing PI3K/AKT-signaling pathway in BEAS-2B immortalized human bronchial epithelial cells. American Association for Cancer Research (AACR) Annual Meeting April 2005, Anaheim, CA, USA, 2005.

Book Chapters

1. Humam Kadara, Wilbur Franklin, Ignacio I. Wistuba. Inflammation and lung cancer: molecular pathology. In: Inflammation & Lung Cancer. Springer, 2015.
2. Humam Kadara and Ignacio I. Wistuba.. Molecular biology of lung preneoplasia. In: Lung Cancer. Fourth edition. Springer US-Cancer Research, 2013.
3. Humam Kadara and Reuben Lotan. Effects of natural and synthetic retinoids on the differentiation and growth of squamous cancers. In: Signaling Pathways in Squamous Cancers. Springer US-Cancer Research, 2010.