M. James You, M.D., Ph.D.

Peer-Reviewed Articles

1. Zang S, Li J, Yang H, Zeng H, Han W, Zhang J, Lee M, Moczygemba M, Isgandarova S, Yang Y, Zhou Y, Rao A, You MJ, Sun D, Huang Y. Mutations in 5-methylcytosine oxidase TET2 and RhoA cooperatively disrupt T cell homeostasis. J Clin Invest 127(8):2998-3012, 2017. e-Pub 2017. PMID: 28691928.
2. Xu S, Wu X, Wu L, Castillo A, Liu J, Atkinson E, Paul A, Su D, Schlacher K, Komatsu Y, You MJ, Wang B. Abro1 maintains genome stability and limits replication stress by protecting replication fork stability. Genes Dev 31(14):1469-1482, 2017. PMID: 28860160.
3. Pant V, Larsson CA, Aryal N, Xiong S, You MJ, Quintas-Cardama A, Lozano G. Tumorigenesis promotes Mdm4-S overexpression. Oncotarget 8(16):25837-25847, 2017. PMID: 28460439.
4. Yuan T, Yang Y, Chen J, Li W, Li W, Zhang Q, Mi Y, Goswami RS, You JQ, Lin D, Qian MD, Calin S, Liang Y, Miranda RN, Calin GA, Zhou X, Ma L, Zweidler-McKay PA, Liu B, Weng AP, Medeiros LJ, Zhang Y, You MJ. Regulation of PI3K signaling in T-cell acute lymphoblastic leukemia: a novel PTEN/Ikaros/miR-26b mechanism reveals a critical targetable role for PIK3CD. Leukemia. e-Pub 2017. PMID: 28280276.
5. Dai F, Lee H, Zhang Y, Zhuang L, Yao H, Xi Y, Xiao ZD, You MJ, Li W, Su X, Gan B. BAP1 inhibits the ER stress gene regulatory network and modulates metabolic stress response. Proc Natl Acad Sci U S A 114(12):3192-3197, 2017. e-Pub 2017. PMID: 28275095.
6. Rezaeian AH, Li CF, Wu CY, Zhang X, Delacerda J, You MJ, Han F, Cai Z, Jeong YS, Jin G, Phan L, Chou PC, Lee MH, Hung MC, Sarbassov D, Lin HK. A hypoxia-responsive TRAF6-ATM-H2AX signalling axis promotes HIF1α activation, tumorigenesis and metastasis. Nat Cell Biol. e-Pub 2016. PMID: 27918549.
7. Xiong S, Pant V, Zhang Y, Aryal NK, James You M, Kusewitt D, Lozano G. The p53 inhibitor Mdm4 cooperates with multiple genetic lesions in tumorigenesis. J Pathol. e-Pub 2016. PMID: 27925213.
8. Xu J, Oki Y, Saksena A, Desai P, Lin P, Tang G, Yin CC, You MJ, Thakral B, Medeiros LJ, Li S. CD30 Expression and Prognostic Significance in R-EPOCH Treated Patients with Diffuse Large B-Cell Lymphoma. Hum Pathol. e-Pub 2016. PMID: 27816715.
9. Van Roosbroeck K, Fanini F, Setoyama T, Ivan C, Rodriguez-Aguayo C, Fuentes-Mattei E, Xiao L, Vannini I, Redis R, D'Abundo L, Zhang X, Nicoloso MS, Rossi S, Gonzalez-Villasana V, Rupaimoole R, Ferracin M, Morabito F, Neri A, Ruvolo P, Ruvolo VR, Pecot CV, Amadori D, Aruzzo L, Calin S, Wang X, You MJ, Ferrajoli A, Orlowski RZ, Plunkett W, Lichtenberg T, Davuluri RV, Berindan-Neagoe I, Negrini M, Wistuba II, Hagop K, Sood AK, Lopez-Berestein G, Keating MJ, Fabbri M, Calin GA. Combining anti-miR-155 with chemotherapy for the treatment of lung cancers. Clin Cancer Res. e-Pub 2016. PMID: 27903673.
10. Tian C, Zheng G, Zhuang H, Li X, Hu D, Zhu L, Wang T, You MJ, Zhang Y. MicroRNA-494 Activation Suppresses Bone Marrow Stromal Cell-Mediated Drug Resistance in Acute Myeloid Leukemia Cells. J Cell Physiol. e-Pub 2016. PMID: 27696394.
11. Dong B, Gao Y, Kang X, Gao H, Zhang J, Guo H, You MJ, Xue W, Cheng J, Huang Y. SENP1 promotes proliferation of clear cell renal cell carcinoma through activation of glycolysis. Oncotarget. e-Pub 2016. PMID: 27741516.
12. Kim J, Siverly AN, Chen D, Wang M, Yuan Y, Wang Y, Lee H, Zhang J, Muller WJ, Liang H, Gan B, Yang X, Sun Y, You MJ, Ma L. Ablation of miR-10b Suppresses Oncogene-Induced Mammary Tumorigenesis and Metastasis and Reactivates Tumor-Suppressive Pathways. Cancer Res. e-Pub 2016. PMID: 27569213.
13. Sergeeva A, He H, Ruisaard K, St John L, Alatrash G, Clise-Dwyer K, Li D, Patenia R, Hong R, Sukhumalchandra P, You MJ, Gagea M, Ma Q, Molldrem JJ. Activity of 8F4, a T-cell receptor-like anti-PR1/HLA-A2 antibody, against primary human AML in vivo. Leukemia 30(7):1475-84, 2016. e-Pub 2016. PMID: 27055866.
14. Chen Z, Cortes JE, Jorgensen JL, Wang W, Yin CC, You MJ, Jabbour E, Kantarjian HM, Medeiros LJ, Hu S. Differential impact of additional chromosomal abnormalities in myeloid vs lymphoid blast phase of chronic myelogenous leukemia in the era of tyrosine kinase inhibitor therapy. Leukemia 30(7):1606-9, 2016. e-Pub 2016. PMID: 26837843.
15. Tian C, You MJ, Yu Y, Zhu L, Zheng G, Zhang Y. MicroRNA-9 promotes proliferation of leukemia cells in adult CD34-positive acute myeloid leukemia with normal karyotype by downregulation of Hes1. Tumour Biol 37(6):7461-71, 2016. e-Pub 2015. PMID: 26678889.
16. Yabe M, Medeiros LJ, Tang G, Wang SA, Ahmed S, Nieto Y, Hu S, Bhagat G, Oki Y, Patel KP, Routbort M, Luthra R, Fanale MA, Bueso-Ramos CE, Jorgensen JL, Vega F, Chen W, Hoehn D, Konoplev S, Milton DR, Wistuba I, Li S, You MJ, Young KH, Miranda RN. Prognostic Factors of Hepatosplenic T-cell Lymphoma: Clinicopathologic Study of 28 Cases. Am J Surg Pathol 40(5):676-88, 2016. PMID: 26872013.
17. Han X, Medeiros LJ, Zhang YH, You MJ, Andreeff M, Konopleva M, Bueso-Ramos CE. High Expression of Human Homologue of Murine Double Minute 4 and the Short Splicing Variant, HDM4-S, in Bone Marrow in Patients With Acute Myeloid Leukemia or Myelodysplastic Syndrome. Clin Lymphoma Myeloma Leuk. e-Pub 2016. PMID: 27155969.
18. Lee H, Dai F, Zhuang L, Xiao ZD, Kim J, Zhang Y, Ma L, You MJ, Wang Z, Gan B. BAF180 regulates cellular senescence and hematopoietic stem cell homeostasis through p21. Oncotarget. e-Pub 2016. PMID: 26992241.
19. Pan D, Jiang C, Ma Z, Blonska M, You MJ, Lin X. MALT1 is required for EGFR-induced NF-κB activation and contributes to EGFR-driven lung cancer progression. Oncogene 35(7):919-28, 2016. e-Pub 2015. PMID: 25982276.
20. Tashakori M, Zhang Y, Xiong S, You MJ, Lozano G. p53 Activity Dominates That of p73 upon Mdm4 Loss in Development and Tumorigenesis. Mol Cancer Res 14(1):56-65, 2016. e-Pub 2015. PMID: 26527653.
21. Riley MF, You MJ, Multani AS, Lozano G. Mdm2 overexpression and p73 loss exacerbate genomic instability and dampen apoptosis, resulting in B-cell lymphoma. Oncogene 35(3):358-65, 2016. e-Pub 2015. PMID: 25915849.
22. You MJ, Medeiros LJ, Hsi ED. T-lymphoblastic leukemia/lymphoma. Am J Clin Pathol 144(3):411-22, 2015. PMID: 26276771.
23. Kang X, Lu Z, Cui C, Deng M, Fan Y, Dong B, Han X, Xie F, Tyner JW, Coligan JE, Collins RH, Xiao X, You MJ, Zhang CC. The ITIM-containing receptor LAIR1 is essential for acute myeloid leukaemia development. Nat Cell Biol 17(5):665-77, 2015. e-Pub 2015. PMID: 25915125.
24. Xia B, Zhang L, Guo SQ, Li XW, Qu FL, Zhao HF, Zhang LY, Sun BC, You J, Zhang YZ. Coexpression of MYC and BCL-2 predicts prognosis in primary gastrointestinal diffuse large B-cell lymphoma. World J Gastroenterol 21(8):2433-42, 2015. PMID: 25741152.
25. Blonska M, Zhu Y, Chuang HH, You MJ, Kunkalla K, Vega F, Lin X. Jun-regulated genes promote interaction of diffuse large B-cell lymphoma with the microenvironment. Blood 125(6):981-91, 2015. e-Pub 2014. PMID: 25533033.
26. Zhang P, Wang L, Rodriguez-Aguayo C, Yuan Y, Debeb BG, Chen D, Sun Y, You MJ, Liu Y, Dean DC, Woodward WA, Liang H, Yang X, Lopez-Berestein G, Sood AK, Hu Y, Ang KK, Chen J, Ma L. miR-205 acts as a tumour radiosensitizer by targeting ZEB1 and Ubc13. Nat Commun 5:5671, 2014. e-Pub 2014. PMID: 25476932.
27. Ma H, Mallampati S, Lu Y, Sun B, Wang E, Leng X, Gong Y, Shen H, Yin CC, Jones D, Amin HM, You MJ, Zweidler-McKay P, Ma Y, Kantarjian HM, Arlinghaus RB, Glassman A, Sun X. The Sox4/Tcf7l1 axis promotes progression of BCR-ABL-positive acute lymphoblastic leukemia. Haematologica 99(10):1591-8, 2014. e-Pub 2014. PMID: 24997151.
28. Wang L, Xiong H, Wu F, Zhang Y, Wang J, Zhao L, Guo X, Chang LJ, Zhang Y, You MJ, Koochekpour S, Saleem M, Huang H, Lu J, Deng Y. Hexokinase 2-mediated Warburg effect is required for PTEN- and p53-deficiency-driven prostate cancer growth. Cell Rep 8(5):1461-74, 2014. e-Pub 2014. PMID: 25176644.
29. Zhang Y, Xiong S, Li Q, Hu S, Tashakori M, Van Pelt C, You MJ, Pageon L, Lozano G. Tissue-specific and age-dependent effects of global Mdm2 loss. J Pathol 233(4):380-91, 2014. e-Pub 2014. PMID: 24789767.
30. Adrada BE, Miranda RN, Rauch GM, Arribas E, Kanagal-Shamanna R, Clemens MW, Fanale M, Haideri N, Mustafa E, Larrinaga J, Reisman NR, Jaso J, You MJ, Young KH, Medeiros LJ, Yang W. Breast implant-associated anaplastic large cell lymphoma: sensitivity, specificity, and findings of imaging studies in 44 patients. Breast Cancer Res Treat 147(1):1-14, 2014. e-Pub 2014. PMID: 25073777.
31. Castillo A, Paul A, Sun B, Huang TH, Wang Y, Yazinski SA, Tyler J, Li L, You MJ, Zou L, Yao J, Wang B. The BRCA1-interacting protein Abraxas is required for genomic stability and tumor suppression. Cell Rep 8(3):807-17, 2014. e-Pub 2014. PMID: 25066119.
32. Zhang L, Singh RR, Patel KP, Stingo F, Routbort M, You MJ, Miranda RN, Garcia-Manero G, Kantarjian HM, Medeiros LJ, Luthra R, Khoury JD. BRAF kinase domain mutations are present in a subset of chronic myelomonocytic leukemia with wild-type RAS. Am J Hematol 89(5):499-504, 2014. e-Pub 2014. PMID: 24446311.
33. Chen D, Sun Y, Yuan Y, Han Z, Zhang P, Zhang J, You MJ, Teruya-Feldstein J, Wang M, Gupta S, Hung MC, Liang H, Ma L. miR-100 induces epithelial-mesenchymal transition but suppresses tumorigenesis, migration and invasion. PLoS Genet 10(2):e1004177, 2014. e-Pub 2014. PMID: 24586203.
34. Warner K, Crispatzu G, Al-Ghaili N, Weit N, Florou V, You MJ, Newrzela S, Herling M. Models for mature T-cell lymphomas-A critical appraisal of experimental systems and their contribution to current T-cell tumorigenic concepts. Crit Rev Oncol Hematol 88(3):680-95, 2013. e-Pub 2013. PMID: 23972664.
35. Tzankov A, Xu-Monette ZY, Gerhard M, Visco C, Dirnhofer S, Gisin N, Dybkaer K, Orazi A, Bhagat G, Richards KL, Hsi ED, Choi WW, van Krieken JH, Ponzoni M, Ferreri AJ, Ye Q, Winter JN, Farnen JP, Piris MA, Møller MB, You MJ, McDonnell T, Medeiros LJ, Young KH. Rearrangements of MYC gene facilitate risk stratification in diffuse large B-cell lymphoma patients treated with rituximab-CHOP. Mod Pathol. e-Pub 2013. PMID: 24336156.
36. Lin S, Tian L, Shen H, Gu Y, Li JL, Chen Z, Sun X, You MJ, Wu L. DDX5 is a positive regulator of oncogenic NOTCH1 signaling in T cell acute lymphoblastic leukemia. Oncogene 32(40):4845-53, 2013. e-Pub 2012. PMID: 23108395.
37. Ferrajoli A, Shanafelt TD, Ivan C, Shimizu M, Rabe KG, Nouraee N, Ikuo M, Ghosh AK, Lerner S, Rassenti LZ, Xiao L, Hu J, Reuben JM, Calin S, You MJ, Manning JT, Wierda WG, Estrov Z, O'Brien S, Kipps TJ, Keating MJ, Kay NE, Calin GA. Prognostic value of miR-155 in individuals with monoclonal B-cell lymphocytosis and patients with B chronic lymphocytic leukemia. Blood 122(11):1891-9, 2013. e-Pub 2013. PMID: 23821659.
38. Jaso JM, Yin CC, Lu VW, Zhao M, Abruzzo LV, You MJ, Yang Y, Luthra R, Medeiros LJ, Lu G. B acute lymphoblastic leukemia with t(14;19)(q32;p13.1) involving IGH/EPOR: a clinically aggressive subset of disease. Mod Pathol. e-Pub 2013. PMID: 24030742.
39. Yost AJ, Shevchuk OO, Gooch R, Gusscott S, You MJ, Ince TA, Aster JC, Weng AP. Defined, serum-free conditions for in vitro culture of primary human T-ALL blasts. Leukemia 27(6):1437-40, 2013. e-Pub 2012. PMID: 23246990.
40. Lu G, Muddasani R, Orlowski RZ, Abruzzo LV, Qazilbash MH, You MJ, Wang Y, Zhao M, Chen S, Glitza IC, Medeiros LJ. Plasma cell enrichment enhances detection of high-risk cytogenomic abnormalities by fluorescence in situ hybridization and improves risk stratification of patients with plasma cell neoplasms. Arch Pathol Lab Med 137(5):625-31, 2013. PMID: 23627452.
41. Yeung SC, Elsayem A, Fuller GN, Lu G, You MJ. Fatal acute monocytic leukaemia with t(6;11)(q27;q23) translocation and KRAS mutation. J Clin Pathol 33(1):73-5, 2013. e-Pub 2012. PMID: 22923764.
42. Redis RS, Calin S, Yang Y, You MJ, Calin GA. Cell-to-cell miRNA transfer: from body homeostasis to therapy. Pharmacol Ther 136(2):169-74, 2012. e-Pub 2012. PMID: 22903157.
43. Yang W, Xia Y, Cao Y, Zheng Y, Bu W, Zhang L, You MJ, Koh MY, Cote G, Aldape K, Li Y, Verma IM, Chiao PJ, Lu Z. EGFR-Induced and PKCε Monoubiquitylation-Dependent NF-κB Activation Upregulates PKM2 Expression and Promotes Tumorigenesis. Mol Cell. e-Pub 2012. PMID: 23123196.
44. Zhou Y, You MJ, Young KH, Lin P, Lu G, Medeiros LJ, Bueso-Ramos CE. Advances in the molecular pathobiology of B-lymphoblastic leukemia. Hum Pathol 43(9):1347-62, 2012. e-Pub 2012. PMID: 22575265.
45. Patel KP, Khokhar FA, Muzzafar T, James You M, Bueso-Ramos CE, Ravandi F, Pierce S, Medeiros LJ. TdT expression in acute myeloid leukemia with minimal differentiation is associated with distinctive clinicopathological features and better overall survival following stem cell transplantation. Mod Pathol. e-Pub 2012. PMID: 22936064.
46. Aladily TN, Medeiros LJ, Amin MB, Haideri N, Ye D, Azevedo SJ, Jorgensen JL, de Peralta-Venturina M, Mustafa EB, Young KH, You MJ, Fayad LE, Blenc AM, Miranda RN. Anaplastic large cell lymphoma associated with breast implants: a report of 13 cases. Am J Surg Pathol 36(7):1000-8, 2012. PMID: 22613996.
47. Qiu X, Sun X, He Z, Huang J, Hu F, Chen L, Lin P, You MJ, Medeiros LJ, Yin CC. Immunoglobulin gamma heavy chain gene with somatic hypermutation is frequently expressed in acute myeloid leukemia. Leukemia. e-Pub 2012. PMID: 22772058.
48. Lu G, Zhang XX, You MJ, Chen W. Correlation of assessment of plasma cells by flow cytometry and detection of cytogenomic abnormalities by fluorescence in situ hybridization in plasma cell neoplasms. Int J Lab Hematol 33(5):545-50, 2011. e-Pub 2011. PMID: 21470373.
49. Vigil CE, Wang SA, Cortes JE, Bueso-Ramos C, Verstovsek S, Shinder R, Chen SS, Katz RL, Khanna A, Esmaeli B, Manning JT, You MJ, Miranda RN. Dasatinib-responsive mast cell neoplasms as initial presentation of chronic myelogenous leukemia in blast phase. J Clin Oncol 29(17):e514-6, 2011. e-Pub 2011. PMID: 21464405.
50. Chen LL, Chen ZL, Chen F, You MJ, Chen L. Sishengsa’s inhibitory effects on the growth of A549 cell line and its acute toxicity. J. Fudan Univ (Natural Science) 50(3):385-389, 2011.
51. Chen H, You MJ, Jiang Y, Wang W, Li L. RMI1 attenuates tumor development and is essential for early embryonic survival. Mol Carcinog 50(2):80-8, 2011. e-Pub 2010. PMID: 21229605.
52. Sun J, Medeiros LJ, Lin P, Lu G, Bueso-Ramos CE, You MJ. Plasmablastic lymphoma involving the penis. Pathology 43(1):54-7, 2011. PMID: 21240066.
53. Ma Q, Wang C, Jones D, Quintanilla KE, Li D, Wang Y, Wieder ED, Clise-Dwyer K, Alatrash G, You MJ, Munsell MF, Lu S, Qazilbash MH, Molldrem JJ. Adoptive transfer of PR1 cytotoxic T lymphocytes associated with reduced leukemia burden in a mouse acute myeloid leukemia xenograft model. Cytotherapy 12(8):1056-62, 2010. e-Pub 2010. PMID: 20735170.
54. Abbas HA, Maccio DR, Coskun S, Jackson JG, Hazen AL, Sills TM, You MJ, Hirschi KK, Lozano G. Mdm2 is required for survival of hematopoietic stem cells/progenitors via dampening of ROS-induced p53 activity. Cell Stem Cell 7(5):606-17, 2010. PMID: 21040902.
55. Medyouf H, Gao X, Armstrong F, Gusscott S, Liu Q, Gedman AL, Matherly LH, Schultz KR, Pflumio F, You MJ, Weng AP. Acute T-cell leukemias remain dependent on Notch signaling despite PTEN and INK4A/ARF loss. Blood 115(6):1175-84, 2010. e-Pub 2009. PMID: 20008304.
56. Dankort D, Curley DP, Cartlidge RA, Nelson B, Karnezis AN, Damsky WE, You MJ, DePinho RA, McMahon M, Bosenberg M. Braf(V600E) cooperates with Pten loss to induce metastatic melanoma. Nat Genet 41(5):544-52, 2009. e-Pub 2009. PMID: 19282848.
57. He H, Wang Y, Guo X, Ramchandani S, Ma J, Shen MF, Garcia DA, Deng Y, Multani AS, You MJ, Chang S. Pot1b deletion and telomerase haploinsufficiency in mice initiate an ATR-dependent DNA damage response and elicit phenotypes resembling dyskeratosis congenita. Mol Cell Biol 29(1):229-40, 2009. e-Pub 2008. PMID: 18936156.
58. Zheng H, Ying H, Yan H, Kimmelman AC, Hiller DJ, Chen AJ, Perry SR, Tonon G, Chu GC, Ding Z, Stommel JM, Dunn KL, Wiedemeyer R, You MJ, Brennan C, Wang YA, Ligon KL, Wong WH, Chin L, DePinho RA. p53 and Pten control neural and glioma stem/progenitor cell renewal and differentiation. Nature 455(7216):1129-33, 2008. PMID: 18948956.
59. de la Iglesia N, Konopka G, Puram SV, Chan JA, Bachoo RM, You MJ, Levy DE, Depinho RA, Bonni A. Identification of a PTEN-regulated STAT3 brain tumor suppressor pathway. Genes Dev 22(4):449-62, 2008. e-Pub 2008. PMID: 18258752.
60. Zheng H, Ying H, Yan H, Kimmelman AC, Hiller DJ, Chen AJ, Perry SR, Tonon G, Chu GC, Ding Z, Stommel JM, Dunn KL, Wiedemeyer R, You MJ, Brennan C, Wang YA, Ligon KL, Wong WH, Chin L, dePinho RA. Pten and p53 converge on c-Myc to control differentiation, self-renewal, and transformation of normal and neoplastic stem cells in glioblastoma. Cold Spring Harb Symp Quant Biol 73:427-37, 2008. e-Pub 2009. PMID: 19150964.
61. Tong S, Liss AS, You MJ, Bose HR. The activation of TC10, a Rho small GTPase, contributes to v-Rel-mediated transformation. Oncogene 26(16):2318-29, 2007. e-Pub 2006. PMID: 17016434.
62. Carrasco DR, Fenton T, Sukhdeo K, Protopopova M, Enos M, You MJ, Di Vizio D, Divicio D, Nogueira C, Stommel J, Pinkus GS, Fletcher C, Hornick JL, Cavenee WK, Furnari FB, Depinho RA. The PTEN and INK4A/ARF tumor suppressors maintain myelolymphoid homeostasis and cooperate to constrain histiocytic sarcoma development in humans. Cancer Cell 9(5):379-90, 2006. PMID: 16697958.
63. Majid SM, Liss AS, You MJ, Bose HR. The suppression of SH3BGRL is important for v-Rel-mediated transformation. Oncogene 25(5):756-68, 2006. PMID: 16186799.
64. Tonon G, Wong KK, Maulik G, Brennan C, Feng B, Zhang Y, Khatry DB, Protopopov A, You MJ, Aguirre AJ, Martin ES, Yang Z, Ji H, Chin L, Depinho RA. High-resolution genomic profiles of human lung cancer. Proc Natl Acad Sci U S A 102(27):9625-30, 2005. e-Pub 2005. PMID: 15983384.
65. Tonon G, Brennan C, Protopopov A, Maulik G, Feng B, Zhang Y, Khatry DB, You MJ, Aguirre AJ, Martin ES, Yang Z, Ji H, Chin L, Wong KK, Depinho RA. Common and contrasting genomic profiles among the major human lung cancer subtypes. Cold Spring Harb Symp Quant Biol 70:11-24, 2005. PMID: 16869734.
66. Bachoo RM, Maher EA, Ligon KL, Sharpless NE, Chan SS, You MJ, Tang Y, DeFrances J, Stover E, Weissleder R, Rowitch DH, Louis DN, DePinho RA. Epidermal growth factor receptor and Ink4a/Arf: convergent mechanisms governing terminal differentiation and transformation along the neural stem cell to astrocyte axis. Cancer Cell 1(3):269-77, 2002. PMID: 12086863.
67. You MJ, Castrillon DH, Bastian BC, O'Hagan RC, Bosenberg MW, Parsons R, Chin L, DePinho RA. Genetic analysis of Pten and Ink4a/Arf interactions in the suppression of tumorigenesis in mice. Proc Natl Acad Sci U S A 99(3):1455-60, 2002. e-Pub 2002. PMID: 11818530.
68. Ku PT, You MJ, Bose HR. Role and regulation of Rel/NF-kappaB activity in anti-immunoglobulin-induced apoptosis in WEHI-231 B lymphoma cells. Cell Signal 12(4):245-53, 2000. PMID: 10781932.
69. You MJ, Bose HR. Identification of v-Rel oncogene-induced inhibitor of apoptosis by differential display. Methods 16(4):373-85, 1998. PMID: 10049645.
70. You MJ, Ku PT, Hrdlicková R, Bose HR. ch-IAP1, a member of the inhibitor-of-apoptosis protein family, is a mediator of the antiapoptotic activity of the v-Rel oncoprotein. Mol Cell Biol 17(12):7328-41, 1997. PMID: 9372964.
71. You MJ, Li CK. T-cell Vaccination. J. Biol. Prod/Foreign Med 12(10):63-66, 1988.

Manuals, Teaching Aids, Other Teaching Publications

1. You MJ. Rel/NF-Kappa B, I-kappa B proteins and their role in apoptosis and tumorigenesis. The University of Texas at Austin: Austin, Texas, 1997.

Abstracts

1. Tian C, Zheng G, You MJ, Zhang Y. Microrna-494 Activation Suppresses Bone Marrow Stromal Cell-Mediated Drug Resistance in Acute Myeloid Leukemia Cells. Annual Meeting, American Society of Hematology, 2016. PMID: 27696394.
2. Rich A, Ai A, Wang W, You MJ, Yin CC, Bueso-Ramos C, Medeiros LJ, Hu S. Pediatric chronic myelogenous leukemia in tyrosine kinase inhibitor era. United States and Canadian Academy of Pathology, Annual Meeting, 2015.
3. Yuan T, Yang YL, Lin D, Jeffrey You QJ, Zhang YZ, You MJ. Down-regulation of miR-26b and its inhibition on the growth of T cell acute lymphoblastic leukemia. Annual Meeting, American Society of Hematology, 2015.
4. Zhang L, Yang YL, Li WH, Miranda R, Dave S, Xin H, Huang X, Jin P, Medeiros LJ, Bueso-Ramos C, You MJ. Expression of MicroRNA-150 is Significantly Decreased in T-acute Lymphoblastic Leukemia (T-ALL) and Inhibits T-ALL Cell Growth. United States and Canadian Academy of Pathology, Annual Meeting, 2014.
5. Chen L, Yang YL, You, MJ. Synergistic effects of Resveratrol and Doxorubicin on inducing the apoptosis of mouse and human Pten deficient T-acute lymphoblastic leukemia cells. Annual meeting, American Association for Cancer Research, 2013.
6. Huang XY, Proctor J, Yang YL, Gao X, Zhang W, Huang SJ, Changelian P, Kutok JL, McGovern, K, You MJ. The potent PI3K δ,γ inhibitor, IPI-145, exhibits preclinical activity in murine and human T-cell acute lymphoblastic leukemia. Annual Meeting, American Society of Hematology, 2013.
7. Shevchuk OO, Yost A, Gooch R, Gusscott S, You MJ, Ince T, Aster JC, Weng AP. Defined, Serum-Free Conditions for in vitro Growth of Primary Human T-ALL blasts. Annual meeting, American Society of Hematology, 2012.
8. Sergeeva A, He H, Ruisaard K, Clise-Dwyer K, John LS, Patenia R, Sukhumalchandra P, Alatrash G, You MJ, Decker WK, Shpall, EJ, MA Q, Molldrem JJ. Treatment with 8F4, an Anti-PR1/HLA-A2 T Cell Receptor-Like Antibody, Reduces Established Acute Myeloid Leukemia and Eliminates Leukemia Stem Cells in Mice. Annual meeting, American Society of Hematology, 2011, 2011.
9. Chen L, Yang Y, Yin CC, Lu G, Chen S, Huang X, Chen J, Chang F, Rahman E, Calin S, Medeiros LJ, Miranda RN, You MJ. Aberrant Expression of Golgin-84 in Non-Hodgkin Lymphomas and Plasma Cell Myeloma. Annual meeting, American Society of Hematology, 2011.
10. Gurevich I, Zhao C, Yin CC, Han X, Lin P, Gao, X, Nguyen MH, Pan E, Medeiros LJ, Bueso-Ramos C, You MJ. Aberrant Nuclear and Loss of PTEN Expression in Acute Myeloid Leukemia. United States and Canadian Academy of Pathology, 2010.
11. Sun J, You MJ. EBV-positive plasmablastic neoplasm. XVth Meeting of the European Association for Hematopathology, 2010.
12. Dai A, Zhao C, Yin CC, Chen L, Sun X, Dave S, Huang H, Zhang YH, Han X, You MJ. Hypermethylation of DBCCR1 Gene in Acute Myeloid Leukemia. Annual meeting, American Association for Cancer Research, 2010.
13. Qiu X, Sun X, He Z, Lin P, You MJ, Chen L, Dai C, Yin CC. Expression of immunoglobulin gene in myeloblasts from patients with acute myelogenous leukemia and its distinct VKJK recombination pattern. Annual meeting, American Association for Cancer Research, 2010.
14. Qui X, Lin P, Sun X, You MJ, Mederios LJ, Yin CC. Mono/Oligo clonal IgH gene rearrangements in acute myeloid leukemia. United States and Canadian Academy of Pathology, 2009.
15. Abbas HA, Coskun S, Sills T, Hirschi KK, You MJ, Lozano G. P53R172P can reversibly arrest hematopietic stem cell activity due to oxidative stress. 2009 Gordon Conference on Stem Cells and Cancer, 2009.
16. Sun B, Mallampati S, Wang D, Lefebvre V, You MJ, Amin HM, Ma Y, Rajewsky K, Gong Y, Sun X. Conditional knockout of Sox4 markedly affects lymophopoiesis in Adult Mice. American Society of Hematology, 2009.
17. Medyouf H, Gao X, Armstrong F, Gusscott S, Liu Q, Gedman AL, Matherly L, Schultz KR, Pflumio F, You MJ*, Weng AP* (*co-corresponding authors). Acute T-Cell Leukemias Remain Dependent on Notch Signaling Despite PTEN Loss. American Society of Hematology, 2009.
18. Zhao C, Dai A, Chen L, Sun X, Han X, Yin CC, You MJ. Epigenetic inactivation of DBC1 in acute myeloid leukemia. American Society of Hematology, 2009.
19. Sergeeva A, Alatrash G, Clise-Dwyer K, Quintanilla KE, Lu S, Ma Q, Li D, Yang Wang Y, You MJ, Molldrem JJ. Anti-PR1/HLA-A2 antibody (8F4, a TCR-mimic) mediates specific lysis of AML stem cells but not normal hematopoietic stem cells. American Society of Hematology, 2009.
20. You MJ, Yin CC, Mederios LJ, Bose HR Jr, Dorman DM. Expression of Golgin-84 in Non-Hodgkin Lymphomasand Plasma Cell Myeloma. United States and Canadian Academy of Pathology, 2008.
21. Konoplev S, Nguyen M, Huang X, Rassidakis GZ, Garcia-Manero G, Yin CC, Amin H, Schlette E, Lin P, Vega-Vazquez F, Admirand J, Huh Y, You MJ, Jorgensen JL, Kantarjian HM, Medeiros LJ, Bueso-Ramos C. Cytoplasmic expression of nucleophosmin does not predict favorable prognosis in AML patients. United States and Canadian Academy of Pathology, 2008.
22. Chan SS, You MJ, Xhang Chang S. Characterization of intestinal phenotypes in the absence of the telomerase binding protein Pot 1a. Mechanisms and Models of Cancer (CSHL), 2008.
23. He H, Wang Y, Guo X, Ranchandani Ma J, Shen MF, Garcia DA, Deng Y, Multani AS, You MJ, Chang S. Pot 1b deletion and Telomerase haploinsufficiency in mice result in phenotyes reembling dyskeratosis congenita. Molecular Genetics of Aging (CSHL), 2008.
24. Liu Q, Gao X, Yin CC, Chen L, You MJ. Resveratrol inhibits proliferation and induces apoptosis of mouse Pten null T-cell acute lymphocytic leukemia cells. American Society Hematology(3967), 2008.
25. Mallampati S, Sun B, Gong Y, Wang E, You MJ, Amin HM, Ma Y, Shen H, Zweidler-McKay P, Jones D, Yin CC, Glassman A, Kantarjian HM, Arlinghaus RB, Sun X. Rooting into the Soil, a Model for the Role of Sox4 in Leukemia. American Society of Hematology, 2008.
26. Curley DP, Dankort D, Bardeesy N, You MJ, Depinho RA, McMahon M, Bosenberg NW. Novel Conditional Inducible mouse models of melanocytic neoplasia:. International Melanoma Congress, 2007.
27. Bachoo RM, Maher EA, Ligon KI, Sharpless NE, Chan SS, You MJ, Tang Y, DeFrances J, Stover E, Weissleder R, Rowitch DH, Louis DN, DePinho RA. Epidermal growth factor receptor and Ink4a/Arf: convergent mechanisms governing terminal differentiation and transformation along the neural stem cell to astrocyte axis. The American Society of Clinical Investigation, 2002.

Book Chapters

1. Wang W, You MJ. Acute panmyelosis with myelofibrosis. In: Case Studies in Hematology and Coagulation. 2nd Edition, 2017.
2. Li SY, You MJ. CLL Richter's transformation. In: Case Studies in Hematology and Coagulation. 2nd Edition, 2017.
3. Xu J, You MJ. T-cell large granulocytic leukemia. In: Case Studies in Hematology and Coagulation. 2nd Edition, 2017.
4. Miranda RM, You MJ, Medeiros LJ. Peripheral T-cell lymphoma, NOS. In: DP Lymphoma Book, 2017.
5. You MJ. Peripheral T-cell lymphoma, NOS. In: DP Lymphoma Book, 2011.
6. You MJ. Mouse Models of Lymphoma and Lymphoid Leukemia. In: Neoplastic Hematopathology: Experimental and Clinical Approaches. Hematology by the Humana Press, Inc, 2010.
7. You MJ, Bueso-Ramos C. Acute panmyelosis with myelofibrosis. In: Case Studies in Hematology and Coagulation, 2010.
8. You MJ, Bueso-Ramos C. CLL Richter's transformation. In: Case Studies in Hematology and Coagulation, 2010.
9. You MJ, Bueso-Ramos C. T-cell large granulocytic leukemia. In: Case Studies in Hematology and Coagulation, 2010.