Jennifer M. Mitchell, VMD DACLAM
Department of Veterinary Medicine and Surgery, Division of Discovery Science
Present Title & Affiliation
Primary Appointment
Section Chief, North Campus Animal Resources, Veterinary Medicine and Surgery, Discovery Sciences, The University of Texas MD Anderson Cancer Center, Houston, Texas
Associate Professor, Veterinary Medicine and Surgery, Discovery Sciences, The University of Texas MD Anderson Cancer Center, Houston, TX
Deputy Department Chair, Veterinary Medicine and Surgery, Discovery Sciences, The University of Texas MD Anderson Cancer Center, Houston, TX
Section Chief, South Campus Animal Resources, Veterinary Medicine and Surgery, Discovery Sciences, The University of Texas MD Anderson Cancer Center, Houston, TX
Dual/Joint/Adjunct Appointment
Associate Professor, Veterinary Medicine and Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX
Education & Training
Degree-Granting Education
| 2007 | University of Pennsylvania School of Veterinary Medicine, Philadelphia, Pennsylvania, US, Veterinary Medicine, VMD |
| 2003 | Drexel University College of Medicine, Philadelphia, Pennsylvania, US, Laboratory Animal Science, MLAS |
| 1999 | Georgetown University, Washington, DC, US, Biology, BS |
Licenses & Certifications
| 2025 | Texas Authorized Personnel Program for Veterinarians |
| 2017 | Diplomate, American College of Laboratory Animal Medicine |
| 2012 | Veterinary License |
| 2007 | DEA Controlled Substances License - Practitioner |
| 2007 | NVAP Category II Accreditation |
Experience & Service
Faculty Academic Appointments
Assistant Professor, Veterinary Medicine and Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX, 2014 - 2021
Instructor, Veterinary Medicine and Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX, 2011 - 2014
Administrative Appointments/Responsibilities
Section Chief, North Campus Animal Resources, Veterinary Medicine and Surgery, The University of Texas MD Anderson Cancer Center, Houston, Texas, 2026 - Present
Deputy Department Chair, Veterinary Medicine and Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX, 2021 - Present
Section Chief, South Campus Animal Resources, Veterinary Medicine and Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX, 2019 - Present
Section Chief ad interim, South Campus Animal Resources, Veterinary Medicine and Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX, 2018 - 2019
Other Professional Positions
Part Time Contract Veterinarian, Low Cost Pet Vax, Houston, TX, 2024 - Present
Reserve Veterinary Medical Officer, United States Department of Agriculture, Washington, District of Columbia, 2013 - 2017
Clinical Veterinarian, Armed Forces Radiobiology Research Institute (Henry M. Jackson Foundation for the Advancement of Military Medicine), Bethesda, Maryland, 2008 - 2011
Associate Veterinarian, Mason-Dixon Equine Associates, Littlestown, PA, 2007 - 2008
Intramural Institutional Committee Activities
Member, DVMS Enrichment Steering Committee, The University of Texas MD Anderson Cancer Center, 2026 - Present
Member, DVMS Enrichment Committee, The University of Texas MD Anderson Cancer Center, 2026 - Present
Member, Institutional Animal Care and Use Committee, The University of Texas MD Anderson Cancer Center, 2025 - Present
SOP Subcommittee Chair, Institutional Animal Care and Use Committee, The University of Texas MD Anderson Cancer Center, 2025 - Present
SOP Subcommittee Vice-Chair, Institutional Animal Care and Use Committee, The University of Texas MD Anderson Cancer Center, 2024 - 2025
Veterinary Medicine Unit - Member, Incident Command System, The University of Texas MD Anderson Cancer Center, 2021 - Present
Member, Junior Faculty Committee, The University of Texas MD Anderson Cancer Center, 2019 - 2021
Selection Committee Member, Chair Selection Committee, Department of Comparative Medicine, The University of Texas MD Anderson Cancer Center, 2019 - 2019
Advisory Committee Member, Chair Selection Committee, Department of Veterinary Medicine and Surgery, The University of Texas MD Anderson Cancer Center, 2018 - 2018
Member, Radiation Safety Committee, The University of Texas MD Anderson Cancer Center, 2017 - Present
Member, Mobile Communications Leadership Team, The University of Texas MD Anderson Cancer Center, 2017 - 2018
Member, Faculty Academic Review Committee, The University of Texas MD Anderson Cancer Center, 2015 - 2018
Alternate Member, Radiation Safety Committee, The University of Texas MD Anderson Cancer Center, 2013 - 2017
Alternate Member, Institutional Animal Care and Use Committee, The University of Texas MD Anderson Cancer Center, 2012 - 2025
Honors & Awards
| 2018 | Charles River Outstanding Clinical Veterinarian Award, Texas Branch of the American Association for Laboratory Animal Science |
Professional Memberships
Selected Presentations & Talks
Local Presentations
- 2014. The Importance of Building a Nest: Insights into Mouse Behavior and Enrichment. Conference. Texas and Louisiana Branches of the American Association for Laboratory Animal Science. Houston, TX, US.
Regional Presentations
- 2025. Live Offspring Born After Grafting of Cryopreserved Prepubertal Rhesus Testis Tissue Back Into the Monkey After Sterilizing Cancer Therapy and Reaching Adulthood. Poster. 30th Annual Texas Forum for Reproductive Sciences. Houston, TX, US.
- 2023. Autologous Testicular Grafting In Rhesus Monkeys Modeling Prepubertal Individuals Undergoing Cancer Therapy. Poster. 28th Annual Texas Forum for Reproductive Sciences. Houston, Texas, US.
- 2017. Increased Physical Activity Decreases Systemic Inflammation and Delays the Development of Pancreatic Ductal Adenocarcinoma in Mice. Conference. Ohio State University Medical Center. Columbus, OH, US.
National Presentations
- 2026. Intelligent Innovation: How AI is Advancing Laboratory Animal Welfare. Invited. 2026 American College of Animal Welfare (ACAW) Short Course. Denver, CO, US.
- 2026. Building Better Scientists: Mouse Biomethodology Training for Graduate Students Improves Animal Welfare. Panelist. 2026 American College of Animal Welfare (ACAW) Short Course.
- 2026. Managing Pitfalls of a Reporting Structure. Invited. Laboratory Animal Management Association (LAMA) 2026 Meeting. San Antonio, Texas, US.
- 2025. Live Offspring Born Using Cryopreserved Prepubertal Rhesis Testis Tissue Autologously Grafted After Sterilizing Cancer Therapy and Reaching Adulthood. Poster. 17th Annual Conference of the Oncofertility Consortium. Detroit, MI, US.
- 2024. Autologous Testicular Grafting In Rhesus Monkeys - A Fertility Preservation Strategy For Prepubertal Males Undergoing Cancer Therapy. Conference. American Society of Andrology. Denver, CO, US.
- 2020. Increased Physical Activity Delays Development of Obesity-Induced Pancreatic Ductal Adenocarcinoma in Mice and Modulates Inflammation. Conference. American Association for Cancer Research Pancreatic Cancer Conference (AACR).
- 2020. Functional Sperm Production in Prepubertally Irradiated Rhesus Monkeys by Spermatogonial Stem Cell Transplantation. Conference. American Society of Andrology. Philadelphia, PA, US.
- 2018. The Dirty Truth: Sanitation of Electronic Devices. Poster. American Association for Laboratory Animal Science. Baltimore, MD, US.
- 2018. Sperm Production in De Novo Formed Seminiferous Tubules from Allogenic Transplanted Testicular Cells in Rhesus Monkey Testis. Conference. American Society of Andrology. Portland, OR, US.
- 2017. Lameness in a Juvenile Rhesus Macaque. Invited. Association of Primate Veterinarians. Austin, TX, US.
- 2012. Animal Models of Acute Radiation Syndrome: Strategies for Post-Exposure Clinical Care. Invited. American Association for Laboratory Animal Science. Minneapolis, MN, US.
- 2010. Cervical Intraepithelial Neoplasia in a Rhesus Macaque. Poster. Association of Primate Veterinarians. Atlanta, GA, US.
International Presentations
- 2026. Effects of Busulfan and Radiation Treatments on Spermatogenesis in a Prepubertal Nonhuman Primate Model of Fertility Preservation. Poster. North American Testis Workshop. Scottsdale, US.
- 2025. Autologous Grafting of Cryopreserved Prepubertal Rhesus Testis Tissue into Adults with Intact Testes Produces Sperm and Offspring. Poster. 50th Annual American Society of Andrology Meeting and Joint International Congress of Andrology Meeting. Washington, D.C, US.
- 2024. Live Offspring Born after Autologous Grafting of Cryopreserved Prepubertal Rhesus Testis Tissue into Adults with Intact Testis after Cytotoxic Cancer Therapy. Conference. 56th Annual Gene Families and Isozymes Conference. San Pedro, BZ.
Formal Peers
- 2017. Animal Welfare. Ft. Detrick, MD, US.
- 2017. Zoonotic Diseases. Ft. Detrick, MD, US.
- 2017. Woodchucks: Biology, Management and Diseases. Ft. Detrick, MD, US.
- 2016. Amphibians: Biology, Management and Diseases. Ft. Detrick, MD, US.
- 2016. Nonhuman Primates: Parasitic and Non-Infectious Diseases. Ft. Detrick, MD, US.
- 2016. Hamsters: Diseases. Ft. Detrick, MD, US.
- 2016. Mice: Biology. Ft. Detrick, MD, US.
- 2016. Guide for the Care and Use of Laboratory Animals: "Musts". Ft. Detrick, MD, US.
- 2010. Ferrets: Biology, Management and Diseases. Invited. Fort Detrick, MD, US.
- 2010. Fundamentals of Laboratory Animal Anesthesia and Analgesia. Invited. Bethesda, MD, US.
Grant & Contract Support
| Date: | 2026 - 2026 |
| Title: | Tunnel Handling to Reduce Stress in Laboratory Mice During Routine Husbandry Procedures |
| Funding Source: | Animal Welfare Institute |
| Role: | PI |
| Date: | 2025 - 2028 |
| Title: | Preservation of Fertility in Male Cancer Patients using a Pharmacological Approach |
| Funding Source: | CANCER PREVENTION RESEARCH INST OF TX |
| Role: | Co-I |
| Date: | 2023 |
| Title: | Targeting the Mucus Degrading Microbiome in Acute Radiation Syndrome |
| Funding Source: | National Institutes of Health |
| Role: | Co-I |
| Date: | 2020 - 2024 |
| Title: | Cancer Center Support (CORE) Grant |
| Funding Source: | NIH/NCI |
| Role: | Other Personnel |
| Date: | 2020 - 2025 |
| Title: | Next Generation Therapies for Preserving Fertility in Male Cancer Patients |
| Funding Source: | Magee Womens Research Institute and Foundation |
| Role: | OSC |
| ID: | R01 HD100197 |
| Date: | 2015 - 2019 |
| Title: | Preserving Male Fertility After Cancer Therapy - Project III - Hormone Suppression and Spermatogenic Recovery After Testicular Irradiation in Primates |
| Funding Source: | NIH/NICHD |
| Role: | Veterinarian |
| ID: | 1 PO1 HD075795-01 |
| Date: | 2015 - 2020 |
| Title: | New Risk Assessment Approach to Personalize Hepatocellular Carcinoma Management |
| Funding Source: | Cancer Prevention & Research Institute of Texas (CPRIT) |
| Role: | Collaborator |
| Date: | 2014 - 2019 |
| Title: | Preserving Male Fertility After Cancer Therapy - Core B: Transplantation |
| Funding Source: | NIH/NICHD |
| Role: | Veterinarian |
| ID: | 1 PO1 HD075795-01 |
| Title: | Evaluation of safety profile, biodistribution , pharmacokinetics and immunogenicity in non-human primates of the novel radiotracer 86Y-CHX-A"-panitumumab F(ab')2 for PET imaging of HER1 expression |
| Funding Source: | Center for Advanced Biomedical Imaging - MI2 |
| Role: | Collaborator |
| Title: | 10-Selective Photothermal Ablation of HCC with Renal Clearable [64Cu] Nanodots |
| Funding Source: | Center for Advanced Biomedical Imaging - MI2 |
| Role: | Collaborator |
| Title: | New Risk Assessment Approach to Personalize Hepatocellular Carcinoma Management |
| Funding Source: | Cancer Prevention & Research Institute of Texas (CPRIT) |
| Role: | Collaborator |
| Title: | In Vivo Investigation of Photoacoustic and Ultrasonic Image-guided Needle Biopsy of the Prostate |
| Funding Source: | Department of Defense (DOD) |
| Role: | Collaborator |
| Title: | Photoacoustic-based investigation of oxygen saturation as an imaging biomarker in a canine model of prostate cancer |
| Funding Source: | Cancer Prevention & Research Institute of Texas (CPRIT) |
| Role: | Collaborator |
| Title: | In Vivo Development of Interstitial-driven Photoacoustic Imaging to Investigate Hypoxia as a Biomarker for Prostate Cancer |
| Funding Source: | NIH/NCI |
| Role: | Collaborator |
Selected Publications
Peer-Reviewed Articles
- Shetty G, Mitchell JM, Gil L, Moore E, Zhang J, Tailor RC, Burd K, Piekarsi N, Burch F, Dozier B, Houser L, Robertson N, Mishler E, Zielen A, Hanna C, Meistrich M, Orwig K. Grafting Cryopreserved Prepubertal Testicular Tissue into a Testis-Intact Rhesus Monkey Produces Sperm and a Healthy Infant. Human Reproduction. e-Pub 2026.
- Shetty G, Mitchell JM, Gil L, Moore E, Zhang J, Tailor RC, Burd K, Piekarsi N, Burch F, Dozier B, Houser L, Robertson N, Mishler E, Hanna C, Meistrich ML, Orwig K. Grafting Cryopreserved Prepubertal Testicular Tissue Into A Testis-Intact Rhesus Monkey Produces Sperm and a Healthy Infant. Science Translational Medicine. e-Pub 2025.
- Pita-Grisanti V, Velez-Bonet E, Chasser K, Hurst Z, Liette A, Vulic G, Dubay K, Lahooti A, Badi N, Ueltschi O, Gumpper-Fedus K, Hsueh HY, Lahooti I, Chavez-Tomar M, Terhorst S, Knoblaugh SE, Cao L, Huang W, Coss CC, Mace TA, Choueiry F, Hinton A, Culp S, Mitchell JM, Schmandt R, Onstad Grinsfelder M, Basen-Engquist K, Cruz-Monserrate Z. Physical Activity Decreases Inflammation and Delays the Development of Obesity-Associated Pancreatic Ductal Adenocarcinoma. Cancer Research 84(18):3058-3071, 2024. e-Pub 2024. PMID: 38781455.
- Ravizzini GC, Erwin W, DePalatis L, Martiniova L, Subbiah V, Paolillo V, Mitchell J, McCoy AP, Gonzalez J, Mawlawi O. Dosimetry of a Novel 111Indium labeled Anti-P-cadherin Monoclonal Antibody (FF-21101) in Non-human Primates. Cancers 15(18):4532, 2023. e-Pub 2023. PMID: 37760501.
- Shetty G, Mitchell JM, Lam TNA, Phan TT, Zhang J, Tailor RC, Peters KA, Penedo MC, Hanna CB, Clark AT, Orwig KE, Meistrich ML. Postpubertal Spermatogonial Stem Cell Transplantation Restores Functional Sperm Production in Rhesus Monkeys Irradiated Before and After Puberty. Andrology 9(5), 2021. e-Pub 2021. PMID: 33960147.
- Shetty G, Mitchell JM, Meyer JM, Wu Z, Lam TNA, Phan TT, Zhang J, Hill L, Tailor RC, Peters KA, Penedo MC, Hanna C, Orwig KE, Meistrich ML. Restoration of Functional Sperm Production in Irradiated Pubertal Rhesus Monkeys by Spermatogonial Stem Cell Transplantation. Andrology 8(5):1428-1441, 2020. e-Pub 2020. PMID: 32351003.
- Muñoz NM, Minhaj AA, Maldonado KL, Kingsley CV, Cortes AC, Taghavi H, Polak U, Mitchell JM, Ensor JE, Bankson JA, Rashid A, Avritscher R. Comparison of dynamic contrast-enhanced magnetic resonance imaging and contrast-enhanced ultrasound for evaluation of the effects of sorafenib in a rat model of hepatocellular carcinoma. Magnetic Resonance Imaging 57:156-164, 2019. e-Pub 2019. PMID: 30465870.
- Sosa E, Chen D, Rojas EJ, Hennebold JD, Peters KA, Wu Z, Lam TN, Mitchell JM, Sukhwani M, Tailor RC, Meistrich ML, Orwig KE, Shetty G, Clark AT. Differentiation of primate primordial germ cell-like cells following transplantation into the adult gonadal niche. Nature Communications 9(1):5339, 2018. e-Pub 2018. PMID: 30559363.
- Shetty G, Mitchell JM, Lam TNA, Wu Z, Zhang J, Hill L, Tailor RC, Peters KA, Penedo MC, Orwig KE, Meistrich ML. Donor Spermatogenesis in DeNovo Formed Seminiferous Tubules from Transplanted Testicular Cells in Rhesus Monkey Testis. Human Reproduction 33(12):2249-2255, 2018. e-Pub 2018. PMID: 30358843.
- King GL, Sandgren DJ, Mitchell JM, Bolduc DL, Blakely WF. System for Scoring Severity of Acute Radiation Syndrome Response in Rhesus Macaques (Macaca mulatta). Comparative Medicine 68(6):1-15, 2018. e-Pub 2018. PMID: 30305197.
- Melancon MP, Appleton Figueira T, Fuentes DT, Tian L, Qiao Y, Gu J, Gagea M, Ensor JE, Muñoz NM, Maldonado KL, Dixon K, McWatters A, Mitchell J, McArthur M, Gupta S, Tam AL. Development of an Electroporation and Nanoparticle-based Therapeutic Platform for Bone Metastases. Radiology 286(1):149-157, 2018. e-Pub 2018. PMID: 28825892.
- Mitchell J, Tinkey PT, Avritscher R, Van Pelt C, Eskandari G, Konnath George S, Xiao L, Cressman E, Morris JS, Rashid A, Kaseb AO, Amin HM, Uthamanthil R. Validation of a Preclinical Model of Diethylnitrosamine-Induced Hepatic Neoplasia in Yucatan Miniature Pigs. Oncology 91(2):90-100, 2016. e-Pub 2016. PMID: 27305144.
- Moroni M, Coolbaugh TV, Lombardini E, Mitchell JM, Moccia KD, Shelton LJ, Nagy V, Whitnall MH. Hematopoietic radiation syndrome in the Gottingen minipig. Radiation Research 176(1):89-101, 2011. e-Pub 2011. PMID: 21520996.
- Moroni M, Coolbaugh TV, Mitchell JM, Lombardini E, Moccia KD, Shelton LJ, Nagy V, Whitnall MH. Vascular access port implantation and serial blood sampling in a Gottingen minipig (Sus scrofa domestica) model of acute radiation injury. Journal of the American Association for Laboratory Animal Science 50(1):65-72, 2011. e-Pub 2011. PMID: 21333166.
- Moccia KD, Olsen CH, Mitchell JM, Landauer MR. Evaluation of hydration and nutritional gels as supportive care after total-body irradiation in mice (Mus musculus). Journal of the American Association for Laboratory Animal Science 49(3):323-328, 2010. e-Pub 2010. PMID: 20587164.
- Guan F, Uboh CE, Soma LR, Birks E, Chen J, Mitchell J, You Y, Rudy J, Xu F, Li X, Mbuy G. LC-MS/MS method for confirmation of recombinant human erythropoietin and darbepoetin alpha in equine plasma. Analytical Chemistry 79(12):4627-4635, 2007. e-Pub 2007. PMID: 17500535.
- Frank JA, Zywicke H, Jordan EK, Mitchell J, Lewis BK, Miller B, Bryant LH, Bulte JW. Magnetic intracellular labeling of mammalian cells by combining (FDA-approved) superparamagnetic iron oxide MR contrast agents and commonly used transfection agents. Academic Radiology 9(Supplement 2):S484-487, 2002. e-Pub 2002. PMID: 12188316.
- Munoz NM, Minaj AA, Maldonado KL, Kingsley CV, Cortes AC, Taghavi H, Polak U, Mitchell JM, Ensor JE, Bankson JA, Rashid A, Bouchard RR, Avritscher R. Detection of early biological effects of multikinase inhibitor therapy in a rat model of hepatocellular carcinoma: comparison of dynamic contrast-enhanced MRI and contrast-enhanced ultrasonography. European Radiology.
- Ravizzini G, Erwin W, De Palatis L, Martiniova L, Subbiah V, Gonzalez Lepera C, Mitchell J, Gonzalez J, McCoy A, Macapinlac H, Tokura M, Paradiso L, Mawlawi O. Dosimetry of a Novel Anti-P-cedherin Radiotracer (FF-21101) in Non-human Primates. Nuclear Medicine and Biology.
Invited Articles
- Barrera A, Duran A, Mitchell J, Jensen VB. Rescue Me: Sanitation of Electronic Devices. Laboratory Animal Science Professional:60-61, 2019. e-Pub 2019.
Review Articles
- Darbyshire, A, Beninson, J, Dyson, MC, Ferguson, L, Freebersyser, J, McFadden, M, Mitchell, J, Petervary, N, Pritt, S, Stokes, WS, Taylor, JM, Vemulapalli, TH, Pritchett-Corning, KR. Social Housing of Postoperative Animals to Support Animal Welfare. Journal of the American Association for Laboratory Animal Science 65(1):11-18, 2026. e-Pub 2026. PMID: 41500529.
- Abdel-Wahab R, Shehata S, Hassan MM, Habra MA, Eskandari G, Tinkey PT, Mitchell J, Lee JS, Amin HM, Kaseb AO. Type I Insulin-Like Growth Factor as a Liver Reserve Assessment Tool in Hepatocellular Carcinoma. Journal of Hepatocellular Carcinoma 2:131-142, 2015. e-Pub 2015. PMID: 27508202.
Editorials
- Mitchell JM, Wafer, L N. Response to Protocol Review Scenario: Submit a New Proposal. Lab Animal 44(2):54-58, 2015.
- Mitchell J. Response to Protocol Review Scenario: Questioning is appropriate. Lab Animal 42(10):356-7, 2013. PMID: 24051637.
Abstracts
- Pita-Grisanti V, Dubay KS, Lahooti A, Badi N, Ueltschi O, Chavez-Tomar M, Terhorst SA, Knoblaugh SE, Coss CC, Mace TA, Choueiry F, Hinton A, Mitchell JM, Basen-Engquist K, Cruz-Monserrate Z. Abstract PO-034 Increased Physical Activity Delays Development of Obesity-Induced Pancreatic Ductal Adenocarcinoma in Mice and Modulates Inflammation. American Association for Cancer Research Pancreatic Cancer Conference (AACR) Virtual Special Conference, 2020. e-Pub 2020.
Patient Reviews
CV information above last modified August 28, 2026