Jiusheng Yan, PhD
Department of Anesthesiology and Perioperative Medicine, Division of Anesthesiology, Critical Care Medicine, and Pain Medicine
Present Title & Affiliation
Primary Appointment
Assistant Professor, Department of Anesthesiology and Perioperative Medicine - Research, Division of Anesthesiology, Critical Care Medicine and Pain Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX
Education & Training
Degree-Granting Education
| 2004 | Purdue University, West Lafayette, IN, USA, PHD, Biochemistry & Molecular Biology |
| 2000 | Institute of Botany, Chinese Academy of Sciences, Beijing, CHN, MS, Botany |
| 1996 | Wuhan University, Wuhan, CHN, BS, Biology |
Postgraduate Training
| 2007-2012 | Research Fellowship, University of Texas at Austin, Austin, TX |
| 2005-2007 | Research Fellowship, University of California at Davis, Davis, CA |
Experience & Service
Other Appointments/Responsibilities
Research Associate, Section of Neurobiology, School of Biological Sciences, The University of Texas at Austin, Austin, TX, 2010 - 2012
Postdoctoral Research Felllow, Section of Neurobiology, School of Biological Sciences, The University of Texas at Austin, Austin, TX, 2007 - 2010
Postdoctoral Research Fellow, Department of Pharmacology, School of Medicine, The University of California at Davis, Davis, CA, 2005 - 2007
Postdoctoral Research Associate, Department of Biological Sciences, Purdue University, West Lafayette, IN, 2005 - 2005
Honors & Awards
| 2008 | AHA Postdoctoral Fellowship, American Heart Association |
Selected Publications
Peer-Reviewed Articles
- Yan J, Aldrich RW. BK potassium channel modulation by leucine-rich repeat-containing proteins. Proc Natl Acad Sci U S A 109(20):7917-22, 2012. e-Pub 2012. PMID: 22547800.
- Yan J, Aldrich RW. LRRC26 auxiliary protein allows BK channel activation at resting voltage without calcium. Nature 466(7305):513-6, 2010. e-Pub 2010. PMID: 20613726.
- Yan J, Olsen JV, Park KS, Li W, Bildl W, Schulte U, Aldrich RW, Fakler B, Trimmer JS. Profiling the phospho-status of the BKCa channel alpha subunit in rat brain reveals unexpected patterns and complexity. Mol Cell Proteomics 7(11):2188-98, 2008. e-Pub 2008. PMID: 18573811.
- Yan J, Dashdorj N, Baniulis D, Yamashita E, Savikhin S, Cramer WA. On the structural role of the aromatic residue environment of the chlorophyll a in the cytochrome b6f complex. Biochemistry 47(12):3654-61, 2008. e-Pub 2008. PMID: 18302324.
- Yan J, Kurisu G, Cramer WA. Intraprotein transfer of the quinone analogue inhibitor 2,5-dibromo-3-methyl-6-isopropyl-p-benzoquinone in the cytochrome b6f complex. Proc Natl Acad Sci U S A 103(1):69-74, 2006. e-Pub 2005. PMID: 16371475.
- Adams KL, Tsoi S, Yan J, Durbin SM, Ramdas AK, Cramer WA, Sturhahn W, Alp EE, Schulz C. Fe vibrational spectroscopy of myoglobin and cytochrome f. J Phys Chem B 110(1):530-6, 2006. PMID: 16471565.
- Kim H, Dashdorj N, Zhang H, Yan J, Cramer WA, Savikhin S. An anomalous distance dependence of intraprotein chlorophyll-carotenoid triplet energy transfer. Biophys J 89(4):L28-30, 2005. e-Pub 2005. PMID: 16055550.
- Dashdorj N, Zhang H, Kim H, Yan J, Cramer WA, Savikhin S. The single chlorophyll a molecule in the cytochrome b6f complex: unusual optical properties protect the complex against singlet oxygen. Biophys J 88(6):4178-87, 2005. e-Pub 2005. PMID: 15778449.
- Yan J, Cramer WA. Molecular control of a bimodal distribution of quinone-analogue inhibitor binding sites in the cytochrome b(6)f complex. J Mol Biol 344(2):481-93, 2004. PMID: 15522300.
- Yan J, Cramer WA. Functional insensitivity of the cytochrome b6f complex to structure changes in the hinge region of the Rieske iron-sulfur protein. J Biol Chem 278(23):20925-33, 2003. e-Pub 2003. PMID: 12672829.
- Yan J, Liu Y, Mao D, Li L, Kuang T. The presence of 9-cis-beta-carotene in cytochrome b(6)f complex from spinach. Biochim Biophys Acta-Bioenerg 1506(3):182-8, 2001. PMID: 11779551.
- Li X, Li Z, Yan J, Li H, Han B, Hu K, Wang A. Investigation of structural change of purple membrane in storage by transmission electron microscope and atomic force microscope. Chinese Science Bulletin 46:1753-56, 2001.
- Yan J, Mao D, Chen H, Kuang T, Li B. Effects of membrane lipids on the electron transfer activity of cytochrome b6f complex from spinach. Acta Botanica Sinica 42:1267-70, 2000.
- Sun Q, Li L, Yan J, Kuang T, Li B. Effects of light and temperature on the expression of the Lhcb2 gene in pea. Acta Bontanica Sinica 42:258-62, 2000.
- Mao D, Yan J, Zhai X, Sun Q, Li l. A new method for purifying Cyt b6f protein complex. Acta Botanica Sinica 40:1022-27, 1998.
Grant & Contract Support
| Title: | Delineation of a LRR family of BK channel auxillary subunits |
| Funding Source: | NIH/NINDS |
| Role: | Principal Investigator |
| Title: | BK channel regulation by auxillary LRR proteins |
| Funding Source: | NIH/NINDS |
| Role: | Principal Investigator |
| Title: | |
| Funding Source: | UT MD Anderson Cancer Center |
| Role: | Principal Investigator |
| Title: | |
| Funding Source: | American Heart Association |
| Role: | Principal Investigator |
Patient Reviews
CV information above last modified November 21, 2023