John N. Weinstein, MD, PhD
Department of Bioinformatics and Computational Biology, Division of Discovery Science
Present Title & Affiliation
Primary Appointment
Professor, Department of Bioinformatics & Comp Biology, Division of Discovery Science, The University of Texas MD Anderson Cancer Center, Houston, Texas
Endowed Distinguished Chair Hubert L. Stringer Chair in Cancer Research, Department of Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center, Houston, TX
Professor (Joint appointment), Department of Systems Biology, The University of Texas MD Anderson Cancer Center, Houston, TX
Education & Training
Degree-Granting Education
| 1971 | Harvard Medical School, Boston, Massachusetts, US, MD |
| 1971 | Harvard University, Cambridge, Massachusetts, US, Ph.D. in Biophysics |
| 1964 | Harvard University, Cambridge, Massachusetts, US, BA in Biology |
Postgraduate Training
| 1972-1973 | Residency in Medicine, Stanford University Medical Center, Stanford, California |
| 1971-1972 | Internship in Medicine, Stanford University Medical Center, Stanford, California |
Licenses & Certifications
| 1973 | California State Medical License |
Experience & Service
Extramural Institutional Committee Activities
Chair, Community of Science Chairs, The University of Texas MD Anderson Cancer Center, 2022 - Present
Vice-Chair, Community of Science Chairs, The University of Texas MD Anderson Cancer Center, 2021 - 2022
Advisor, RPPA Core and Metabolomics Core, The University of Texas MD Anderson Cancer Center, 2021 - Present
Advisory Board, Metabolomics Core, The University of Texas MD Anderson Cancer Center, 2021 - Present
Lead Co-Chair, The Data Science Forum (in association with the newly forming Institute for Data Science in Oncology (2023-present), The University of Texas MD Anderson Cancer Center, 2021 - Present
Member, RAI Committee (evaluating major institutional informatics projects), The University of Texas MD Anderson Cancer Center, 2021 - Present
Advisor, Single-Cell Sequencing Core, The University of Texas MD Anderson Cancer Center, 2021 - Present
Co-Chair, Research Leadership Team (RLT) Data Management Working Team, The University of Texas MD Anderson Cancer Center, 2020 - Present
Member, D3CODE, The University of Texas MD Anderson Cancer Center, 2020 - Present
Co-Chair (with David Jaffray), Data Science and Modeling Initiative at MD Anderson, The University of Texas MD Anderson Cancer Center, 2020 - 2022
Member, Community of Science Chairs, The University of Texas MD Anderson Cancer Center, 2019 - Present
Co-founder/Advisor, GSBS Single-Cell Sequencing Course, The University of Texas MD Anderson Cancer Center, 2019 - Present
Advisor, CPRIT Single Cell Genomics Center, The University of Texas MD Anderson Cancer Center, 2017 - Present
Member, Translational Research Strategic Planning Committee, The University of Texas MD Anderson Cancer Center, 2014 - Present
Member, Technology Task Force, The University of Texas MD Anderson Cancer Center, 2013 - 2014
Supervisor (co-director), UT MD Anderson CCSG Metabolomics Core Facility, The University of Texas MD Anderson Cancer Center, 2013 - Present
Evaluator, Chief Information Officer Recruitment, The University of Texas MD Anderson Cancer Center, 2012 - Present
Member, Chief Research Information Officer (CRIO) Recruitment Committee, The University of Texas MD Anderson Cancer Center, 2012 - Present
Advisor, Reverse Phase Protein Array (RPPA) Core, The University of Texas MD Anderson Cancer Center, 2012 - Present
Chair, Institutional Research Executive Committee (IREC) Bioinformatics Subcommittee, The University of Texas MD Anderson Cancer Center, 2012 - 2012
Member, Organizing Committee, GSBS Course, "Introduction to Bioinformatics", The University of Texas MD Anderson Cancer Center, 2012 - Present
Member, Institutional Research Executive Committee (IREC) IT Subcommittee, The University of Texas MD Anderson Cancer Center, 2012 - Present
Member, MD Anderson Technology Task Force, The University of Texas MD Anderson Cancer Center, 2010 - Present
Faculty Member, The University of Texas Graduate School of Biomedical Sciences at Houston, The University of Texas MD Anderson Cancer Center, 2009 - Present
Member, The Cancer Prevention Research Institute of Texas (CPRIT) Grant Planning Committee, The University of Texas MD Anderson Cancer Center, 2009 - Present
Member, Clinical Trials Network, The University of Texas MD Anderson Cancer Center, 2009 - Present
Member, Adelson Medical Research Foundation (AMRF), The University of Texas MD Anderson Cancer Center, 2008 - Present
Member, Center for Clinical and Translational Sciences (CCTS), The University of Texas MD Anderson Cancer Center, 2008 - Present
Member, cancer Biomedical Informatics Grid (caBIG), The University of Texas MD Anderson Cancer Center, 2008 - 2010
Member, The Gulf Coast Center for Computational Cancer Research (GCCC), The University of Texas MD Anderson Cancer Center, 2008 - Present
Member, Biomarker-Based Approaches of Targeted Therapy for Lung Cancer Elimination (BATTLE), The University of Texas MD Anderson Cancer Center, 2008 - 2011
Member, Ovarian Cancer Research Fund (OCRF), The University of Texas MD Anderson Cancer Center, 2008 - 2010
Member, M. D. Anderson Cancer Center Executive Committee of the Science Faculty (ECSF), The University of Texas MD Anderson Cancer Center, 2008 - 2012
Member, Research Education and Information Systems Steering Team (RE&ISST), The University of Texas MD Anderson Cancer Center, 2008 - Present
Member, Steering Committee of the Institute for Personalization of Cancer Therapy (IPCT), The University of Texas MD Anderson Cancer Center, 2008 - Present
Editorial Activities
Ad Hoc Editor, Proc. Natl Acad. Sci U.S.A, 2014 - Present
Senior Editor, Cancer Research, 2013 - 2015
Editor, Current Cancer Drug Target, 2008 - Present
Honors & Awards
| 2023 | h-index raised to 135 (Scopus), with >400 publication, including 14 as first author in Science (11) and Nature (3) |
| 2021 | 2020 AACR Team Science Award, American Association for Cancer Research |
| 2020 | “Highly-Cited Scientist of the Decade”, Web of Science |
| 2017 | Nominee, The Break Through Prize in the Life Sciences |
| 2015 | Best Boss Award, The University of Texas MD Anderson Cancer Center |
| 2014 | Nominee, The Dan David Prize, the Dan David Foundation |
| 2011 | Nominee, Mentoring Excellence Award, The University of Texas MD Anderson Cancer Center |
| 2011 | Nominee, The Japan Prize, The Japan Prize Foundation |
| 2010 | Nominee, Bower Award and Prize for Achievement in Science |
| 2008 | Nominee, Institute of Medicine of the National Academy of Sciences |
| 2006 | Undergraduate Scholarship Program Recognition Award, National Institutes of Health |
| 2006 | NCI Director's Innovation Award, National Cancer Institute |
| 2006 | Technology Transfer Award |
| 2005 | CLAS Distinguished Scientist Award |
| 2004 | Nominee, National Medal of Technology |
| 2002 | General Motors Lecturer |
| 1999 | Public Health Service Meritorious Service Medal |
| 1998 | NCI Intramural Research Award, NCI |
| 1996 | NIH Commendation Medal, NIH |
| 1995 - 1997 | Equal Employment Opportunity Officer's Awards |
| 1988 | Public Health Service Outstanding Service Medal |
| 1987 | Creasy Memorial Lectureship, Sloan-Kettering and Cornell Medical School |
| 1960 - 1964 | Honorary National Scholarship |
| 1960 - 1961 | Harvard College Scholarship |
Professional Memberships
Selected Presentations & Talks
Regional Presentations
- 2008. Computational Biology Working Group. Conference. Computational Biology Working Group. Austin, TX, US.
National Presentations
- 2016. Comprehensive molecular characterization of 412 muscle-invasive urothelial bladder carcinomas: final analysis of The Cancer Genome Atlas (TCGA) project. Conference. Comprehensive molecular characterization of 412 muscle-invasive urothelial bladder carcinomas: final analysis of The Cancer Genome Atlas (TCGA) project. New Orleans, LA, US.
- 2016. Comprehensive molecular characterization of 412 muscle-invasive urothelial bladder carcinomas: final analysis of The Cancer Genome Atlas (TCGA) project. Conference. AACR. New Orleans, LA, US.
- 2012. TCGA 2nd Annual Symposium. Conference. TCGA 2nd Annual Symposium. Crystal City, VA, US.
- 2012. TCGA PAN-Cancer Workshop. Conference. TCGA PAN-Cancer Workshop. Santa Cruz, CA, US.
- 2012. American Association for Cancer Research. Conference. American Association for Cancer Research. Chicago, IL, US.
- 2011. Personalizing Cancer Medicine: Bioinformatics and the Omic Revolution. Conference. IEEE - GENSIPS’11. San Antonio, TX, US.
- 2011. The Cancer Genome Atlas (TCGA). Conference. The Cancer Genome Atlas (TCGA). National Harbor, MD, US.
- 2011. 7th EDRN Scientific Meeting. Conference. 7th EDRN Scientific Meeting. Bethesda, MD, US.
- 2011. TCGA with Respect to Informatics and Biomarkers. Conference. TCGA with Respect to Informatics and Biomarkers. Bethesda, MD, US.
- 2011. Batch Effects. Conference. The Cancer Genome Atlas (TCGA). North Bethesda, MD, US.
- 2011. American Association for Cancer Research. Conference. American Association for Cancer Research. Orlando, FL, US.
- 2010. Analyzing TCGA Data: A novel, systems-oriented method for diagnosing batch effects and adjusting for them. Conference. American Association for Cancer Research. Washington, DC, US.
- 2009. Bioinformatics and personalization of cancer management: the data tsunami. Conference. Frontiers of Cancer Research: Biology, Emerging Technologies and Therapeutics. Houston, TX, US.
- 2009. The Future of Genomic Medicine II. Conference. The Future of Genomic Medicine II. La Jolla, CA, US.
- 2008. High Performance Computing in the 'Personalization' of Cancer Therapy: Genomics, Proteomics, and Bioinformatics. Conference. Supercomputing Conference 08. Austin, TX, US.
- 2008. An Integromic Approach to Drug and Biomarker Discovery. Conference. 61st Annual Symposium on Cancer Research on Systems Biology. Houston, TX, US.
International Presentations
- 2010. American Association for Cancer Research. Conference. American Association for Cancer Research. Amsterdam, NL.
- 2009. Personalizing Cancer Medicine: The Bioinformatic Challenge of Data Integration. Conference. Personalizing Cancer Medicine: The Bioinformatic Challenge of Data Integration. Beijing, CN.
- 2009. Personalizing cancer therapy: pharmacogenomics, pharmacoproteomics, and pharmacoinformatics. Conference. Frontiers of Pharmaceutical Sciences. Toronto, CA.
- 2008. Omix molecular profiling and bioinformatics in the personalization of medicine. Conference. 2008 Annual OMIX Symposium. Tokyo, JP.
- 2008. How Systems Biology can advance Cancer Research. Conference. How Systems Biology can advance Cancer Research. Bruxelles, BE.
Formal Peers
- 2017. Rigor and Reproducibility Workshop. Invited, TX, US.
- 2013. SouthWest Oncology Group (SWOG). Invited. Chicago, IL, US.
- 2013. SouthWest Oncology Group. Invited. San Francisco, CA, US.
- 2012. RapTOR External Advisory Board. Invited. Livermore, CA, US.
- 2012. "Omics and Integration in Biology and Medicine. Invited. Bethesda, MD, US.
- 2012. USC-PSOC and ASU-CASI Workshop. Invited. Scottsdale, AZ, US.
- 2011. 7th EDRN Scientific Meeting. Invited. Bethesda, MD, US.
- 2011. Translational Science Meeting 2011: From Molecular Information to Cancer Medicine. Invited. Washington, DC, US.
- 2011. The University of California at San Francisco SPORE Meeting. Invited. San Francisco, CA, US.
- 2011. The Cancer Genome Atlas (TCGA) Lung Analysis Workshop Group Meeting. Invited. Chapel Hill, NC, US.
- 2011. Computational Biology and Bioinformatics. Invited. College Station, TX, US.
- 2011. The Cancer Genome Atlas (TCGA) Steering Committee Meeting. Invited. Bethesda, MD, US.
- 2011. Bioinformatics in the Personalization of Cancer Medicine. Invited. St. Louis, MO, US.
- 2010. The Cancer Genome Atlas (TCGA) Steering Committee Meeting. Invited. Long Beach, CA, US.
- 2010. Hematology Oncology. Invited. Baltimore, MD, US.
- 2010. The Cancer Genome Atlas (TCGA) Steering Committee Meeting. Invited. Bethesda, MD, US.
- 2010. Bioinformatics and Systems Biology Analysis of high-throughput data; identification of biomarkers for cancer risk and outcome using a systems biology approach; available tools and programs. Invited. Houston, TX, US.
- 2009. TCGA Ovarian Cancer Workshop. Invited. Berkeley, CA, US.
- 2009. Cancer & Cell Biology Division Annual Retreat. Invited. Phoenix, AZ, US.
- 2008. The Cancer Genome Atlas Steering Committee Meeting. Invited. Bethesda, MD, US.
- 2008. Personalizing cancer therapy: Genomics, proteomics, and bioinformatics. Invited. Tokyo, JP.
- 2008. Personalizing cancer therapy: Integrative genomics, proteomics, and bioinformatics. Invited. Washington, DC, US.
- 2008. The Cancer Genome Atlas Pilot Project Steering Committee Meeting. Invited. New York, NY, US.
- 2008. Developing the tools and Technologies To Move From Data to Knowledge. Invited. Columbus, OH, US.
- 2008. High-Throughput Integromic Profiling of Cancer Cells: Genomics, Proteomics, and Bioinformatics. Invited. Orlando, FL, US.
- 2008. Futures Workshop on Personalized Medicine. Invited. Houston, TX, US.
- 2008. Integromic Analysis of Drug and Radiation Effects on Cancer Cells: Genomics, Proteomics, and Bioinformatics. Invited. Washington, DC, US.
Grant & Contract Support
| Date: | 2024 - 2029 |
| Title: | Enhancing Next-Generation Clustered Heat Maps, including support for the integrated analysis and visualization of multi-omic data |
| Funding Source: | NIH/NCI |
| Role: | MPI |
| ID: | AN:4847549 |
| Date: | 2022 - 2027 |
| Title: | The Cancer Proteome Atlas: An Integrated Bioinformatics Resource for Functional Cancer Proteomic Data |
| Funding Source: | NCI |
| Role: | Co-I |
| ID: | 5U24CA264128 |
| Date: | 2022 - 2025 |
| Title: | OmicBlender: A Web Resource for Dynamically Interactive Visual Integration of User-Generated and Public Molecular Profiling Data Sets |
| Funding Source: | NIH/NCI |
| Role: | Co-PI |
| ID: | 1 U01 CA 274571 - 01 |
| Date: | 2022 - 2027 |
| Title: | MD Anderson proteogenomic data analysis center for CPTAC |
| Funding Source: | NIH/NCI |
| Role: | Co-PI |
| ID: | 1 U24 CA271078-01 |
| Date: | 2021 - 2026 |
| Title: | A Genome Data Analysis Center Focused on Batch Effect Analysis and Data Integration |
| Funding Source: | NIH/NCI |
| Role: | MPI |
| ID: | U24CA264006 |
| Date: | 2021 - 2026 |
| Title: | A Web Resource for Dynamically Interactive Visual Integration of User-Generated and Public Molecular Profiling Data Sets |
| Funding Source: | NIH/NCI |
| Role: | Co-PI |
| ID: | R01 CA266333 |
| Date: | 2021 - 2021 |
| Title: | An Advanced Next-Generation Clustered Heat Map System for Visualization and Analysis of Large Omic Datasets, with a Version Customized |
| Funding Source: | NIH/NCI |
| Role: | Multi PI |
| ID: | U24 CA253371 |
| Date: | 2021 - 2026 |
| Title: | Mouse models of leukemia |
| Funding Source: | NIH/NCI |
| Role: | PI |
| ID: | 1R01 CA25250-01 |
| Date: | 2020 - 2025 |
| Title: | Deciphering Functional Consequences of Specific and Combinatorial Mutations in Protein Interaction Networks |
| Funding Source: | NIH/NCI |
| Role: | OSC |
| ID: | 5 R35GM137836-04 |
| Date: | 2020 - 2023 |
| Title: | Combination of immuno- and targeted therapies guided by multi-omics characterization of the TP53 pathway, TGF-beta and stromal signature in breast cancer |
| Funding Source: | DOD/Congressionally Directed Medical Research Programs (DOD/CDMRP) |
| Role: | CO-I |
| ID: | BC200871 |
| Date: | 2020 - 2025 |
| Title: | Informatics for Cancer Research Education and Training (iCREAT) |
| Funding Source: | NIH via UT Health Science |
| Role: | Principal Investigator-MDACC |
| ID: | FP9999 |
| Date: | 2020 - 2025 |
| Title: | An Advanced Next-Generation Clustered Heat Map System for Visualization and Analysis of Large Omic Datasets, with a Version Customized for Single-Cell Sequencing Data |
| Funding Source: | NIH/NCI |
| Role: | Co-PI |
| ID: | U24 CA253371 |
| Date: | 2020 - 2025 |
| Title: | Bladder Cancer Evolution from Field Effects by Whole-Organ Mapping |
| Funding Source: | NIH/NCI |
| Role: | Collaborator |
| ID: | R01 CA247866 |
| Date: | 2020 - 2025 |
| Title: | Identification of Clinically Relevant Genomic Signatures of Lethal Variants of Bladder Cancer |
| Funding Source: | NIH/NCI |
| Role: | Collaborator |
| ID: | R01 CA247657 |
| Date: | 2019 - 2024 |
| Title: | Integrating Theory with Experiment to Discover Biomolecular Mechanisms |
| Funding Source: | Sandia National Laboratories (Subaward via NIH) |
| Role: | Principal Investigator-MDACC |
| Date: | 2019 - 2024 |
| Title: | CCSG (CORE) ProgInc -Developing SR-Metabolomics |
| Funding Source: | NIH/NCI |
| Role: | CO-I |
| ID: | P30CA016672 |
| Date: | 2019 - 2026 |
| Title: | Cancer Center Support Grant - Biostatistics Shared Resource (Bioinformatics Resource Group) |
| Funding Source: | NIH/NCI |
| Role: | Core Leader |
| ID: | P30CA016672 |
| Date: | 2019 - 2024 |
| Title: | MBatch: A highly interactive computational resource for detecting, diagnosing, visualizing, interpreting, and correcting batch and trend effects in cancer molecular profiling data |
| Funding Source: | NIH/NCI |
| Role: | PI |
| Date: | 2019 - 2022 |
| Title: | Toward curative therapy for hematologic diseases by metronomic administration of L-asparaginase |
| Funding Source: | Leukemia and Lymphoma Society |
| Role: | PI |
| Date: | 2018 - 2022 |
| Title: | Computational Tools for Analysis and Visualization of Quality Control Issues in Metabolomic Data |
| Funding Source: | NIH/NCI |
| Role: | PI |
| ID: | 5 U01 CA235510 - 05 |
| Date: | 2018 - 2023 |
| Title: | Multidimensional Mapping of the path from polyp to cancer: a chapter in the PreCancer Atlas |
| Funding Source: | Mayo Clinic (Subaward via NIH) |
| Role: | CO-I |
| Date: | 2017 - 2021 |
| Title: | Reaction Mechanism in Therapeutic Asparaginases: Re-designing Enzymes for Faster Catalysis and Customized Selectivity |
| Funding Source: | Sandia National Laboratories (Subaward with NIH) |
| Role: | MDACC PI |
| Date: | 2017 - 2019 |
| Title: | Development of L-asparaginase Analogs with Improved Therapeutic Index |
| Funding Source: | ALEX'S LEMONADE STAND FOUNDATION |
| Role: | PI |
| ID: | FP00001724 |
| Date: | 2017 - 2019 |
| Title: | Defining roles for leukemia inhibitory factor in dendritic cell development and function |
| Funding Source: | NIH/NCI |
| Role: | Collaborator |
| ID: | FP00001824 |
| Date: | 2017 - 2022 |
| Title: | Identification of potentially targetable pathways in rare cancers by borrowing information from common cancers through the analysis of TCGA omics data |
| Funding Source: | NIH/NCI |
| Role: | CO-I |
| ID: | R01 CA215106 |
| Date: | 2017 - 2018 |
| Title: | "Next-Generation" Clustered Heat Maps for fluent, interactive exploration of omic data: IVYGAP Supplement |
| Funding Source: | NIH/NCI |
| Role: | Co-PI |
| Date: | 2016 - 2021 |
| Title: | Integrated analysis of protein expression data from the Reverse Phase Protein Array (RPPA) platform |
| Funding Source: | NCI |
| Role: | Co-PI |
| ID: | U24 CA210950 |
| Date: | 2016 - 2021 |
| Title: | Batch effects in molecular profiling data on cancers: detection, quantitation, interpretation, and correction |
| Funding Source: | NIH/NCI |
| Role: | PI |
| ID: | U24 CA210949 |
| Date: | 2016 - 2021 |
| Title: | TCPA: an Integrated Bioinformatics Resource for Functional Cancer Proteomic Data |
| Funding Source: | NIH/NCI |
| Role: | CO-I |
| ID: | U24 CA 209851 |
| Date: | 2016 - 2017 |
| Title: | Genomic Data Analysis Network: Specialized Genomic Data Center (U24) |
| Funding Source: | NIH/NCI |
| Role: | PI |
| ID: | U24 |
| Date: | 2016 - 2021 |
| Title: | CPRIT MIRA Core 3- Biostatistics/Bioinformatics |
| Funding Source: | Cancer Prevention & Research Institute of Texas (CPRIT) |
| Role: | Collaborator |
| ID: | RP160693 C3 |
| Date: | 2016 - 2019 |
| Title: | Mechanisms of carcinogenesis and therapeutic vulnerabilities associated with RBM10 loss in KRAS mutant NSCLC |
| Funding Source: | Department of Defense Lung Cancer Development |
| Role: | Collaborator |
| ID: | LC150174 |
| Date: | 2016 - 2016 |
| Title: | Integrative Pipeline for Analysis & Translational Application of TCGA Data: The University of Texas MD Anderson TCGA Genome Data Analysis Center |
| Funding Source: | NIH/NCI |
| Role: | Lead PD/PI |
| ID: | 3 U24 CA143883 05S2 |
| Date: | 2016 - 2016 |
| Title: | Functional and quantitative analysis of PARP protein variants and post-translational modifications |
| Funding Source: | Rockland-NIH (SBIR) |
| Role: | CO-I |
| Date: | 2015 - 2020 |
| Title: | Next-Generation Clustered Heat Maps for fluent, interactive exploration of omic data |
| Funding Source: | NCI |
| Role: | PI |
| ID: | U24 CA199461 |
| Date: | 2015 - 2021 |
| Title: | "Next Generation" clustered Heat Maps for fluent, interactive exploration of omic data |
| Funding Source: | NCI |
| Role: | PI |
| ID: | U24 CA199461 |
| Date: | 2015 - 2018 |
| Title: | Center for Analysis, Interpretation, and Visualization of Biomedical Big Data |
| Funding Source: | NIH/NCI |
| Role: | Principal Investigator-MDACC |
| ID: | 1U54HG008069-01 |
| Date: | 2015 - 2016 |
| Title: | Omic Explorer: An interactive resource for collaborative visualiziation-guided discovery |
| Funding Source: | NIH/NCI |
| Role: | Co-PI |
| ID: | 11682986 |
| Date: | 2014 - 2015 |
| Title: | Development of L-asparaginase analogs with improved therapeutic index |
| Funding Source: | Leukemia and Lymphoma Society |
| Role: | PI |
| Date: | 2014 - 2018 |
| Title: | Center for Analysis, Interpretation, and visualization of Biomedical Big Data |
| Funding Source: | NIH/NCI |
| Role: | Co-PI |
| Date: | 2013 - 2019 |
| Title: | A Proteomics and Metabolomics Core Facility at the University of Texas MD Anderson Cancer Center |
| Funding Source: | Cancer Prevention & Research Institute of Texas (CPRIT) |
| Role: | PI |
| ID: | RP130397 |
| Date: | 2013 - 2018 |
| Title: | The University of Texas MD Anderson Cancer Center SPORE in Leukemia (Core C: Biostatistics, Data Management, and Bioinformatics) |
| Funding Source: | NIH/NCI |
| Role: | Core Co-Director |
| ID: | 5P50CA100632 |
| Date: | 2012 - 2017 |
| Title: | Center for Clinical and Translational Research (CCTS) |
| Funding Source: | NIH/NCI |
| Role: | Collaborator - Research Informatics |
| ID: | 4 UL1 TR000371-10 |
| Date: | 2012 - 2017 |
| Title: | Training of Academic Head and Neck Surgical Oncologist |
| Funding Source: | NIH/NCI |
| Role: | Faculty Mentor |
| ID: | 2 T32 CA060374 16 |
| Date: | 2012 - 2015 |
| Title: | CyTof Mass Cytometer and Element Tagging System |
| Funding Source: | Cancer Prevention & Research Institute of Texas (CPRIT) |
| Role: | TO BE DETERMINED |
| ID: | RFA R-12-SIA-1 |
| Date: | 2011 - 2016 |
| Title: | The Cancer Reclassification Project |
| Funding Source: | NIH/NCI |
| Role: | PI |
| ID: | 1 R01 CA163260 01 |
| Date: | 2011 - 2016 |
| Title: | CyTOF Mass Cytometer and Element Tagging System |
| Funding Source: | Cancer Prevention & Research Institute of Texas (CPRIT) |
| Role: | Collaborator |
| ID: | RP110775 |
| Date: | 2011 - 2016 |
| Title: | CPRIT Proteomics Center: Biomarker and Target Discovery Core 2: Informatics and Systems Biology and Biostatistics |
| Funding Source: | Cancer Prevention & Research Institute of Texas (CPRIT) |
| Role: | Core Leader |
| ID: | RP110694 |
| Date: | 2011 - 2021 |
| Title: | The Lorraine Dell Program in Bioinformatics for Personalization of Cancer Medicine |
| Funding Source: | Michael and Susan Dell Foundation |
| Role: | PI |
| ID: | CV11121361 |
| Date: | 2011 - 2015 |
| Title: | Expression and evolution of young duplicate genes in the human genome |
| Funding Source: | NIH/NIGMS |
| Role: | CO-I |
| ID: | 1 R01 GM097266 01 |
| Date: | 2011 - 2016 |
| Title: | BATTLE-2: Personalizing Non-Small Cell Lung Cancer Therapy |
| Funding Source: | NIH/NCI |
| Role: | Co-Core Director |
| ID: | 1 P01 CA148133 01A1 |
| Date: | 2011 - 2016 |
| Title: | Integrated Multi-Analytic Molecular Signatures In Acute Myelogenous Leukemia |
| Funding Source: | NIH/NCI |
| Role: | Investigator |
| ID: | 1 U01 CA157711 01 |
| Date: | 2010 - 2015 |
| Title: | Metabolic and Molecular Targets for Breaking the Obesity-Cancer Link: Fuel for Future Interventions |
| Funding Source: | NIH (Subcontract from the University of Texas, Austin) |
| Role: | CO-I |
| Date: | 2010 - 2015 |
| Title: | Institutional Clinical and Translational Science Award (U54) |
| Funding Source: | NIH/NCRR (Subcontract from The University of Texas Health Science Center) |
| Role: | CO-I |
| ID: | 2 UL1 RR024148 05 |
| Date: | 2010 - 2013 |
| Title: | Comprehensive Analysis of Genetic and Epigenetic Changes in Oral Cancer |
| Funding Source: | Cancer Prevention & Research Institute of Texas (CPRIT) |
| Role: | Collaborator |
| ID: | RP100233-02 |
| Date: | 2010 - 2015 |
| Title: | CPRIT Proteomics Center: Biomarker and Target Discovery (PC-D) |
| Funding Source: | Cancer Prevention & Research Institute of Texas (CPRIT) |
| Role: | Core Leader |
| Date: | 2010 - 2015 |
| Title: | CPRIT Proteomics Center: Biomarker and Target Discovery (PP-1) |
| Funding Source: | Cancer Prevention & Research Institute of Texas (CPRIT) |
| Role: | Project Leader |
| Date: | 2010 - 2015 |
| Title: | Genomic, Epigenomic, and Transcriptome Profile of Bladder Cancer Development |
| Funding Source: | Cancer Prevention & Research Institute of Texas (CPRIT) |
| Role: | Co-Core Leader |
| ID: | RP101298 |
| Date: | 2010 - 2015 |
| Title: | CPRIT Proteomics Center: Biomarker and Target Discovery (PC-C) |
| Funding Source: | Cancer Prevention & Research Institute of Texas (CPRIT) |
| Role: | Core Leader |
| Date: | 2010 - 2015 |
| Title: | Biomarker Development for Acute Myelogenous Leukemia with Complex Karyotype |
| Funding Source: | NIH/NCI |
| Role: | Significant Contributor |
| ID: | 1 UO1 CA152812 01 |
| Date: | 2010 - 2015 |
| Title: | New Approaches to the Biology and Treatment of Myelodysplastic Syndrome (MDS) (PC-C) |
| Funding Source: | NIH/NCI |
| Role: | Co-Core Director |
| ID: | 2 P01 CA108631 06 |
| Date: | 2010 - 2021 |
| Title: | Philanthropic Funds |
| Funding Source: | Mary K. Chapman Foundation |
| Role: | PI |
| ID: | 80-107216-19 |
| Date: | 2009 - 2014 |
| Title: | Genomic, Epigenomic, and Transcriptome Profile of Bladder Cancer Development |
| Funding Source: | NIH/NCI |
| Role: | Core Co-Director |
| ID: | 1 P01 CA142567 01 |
| Date: | 2009 - 2014 |
| Title: | p53 regulates ER alpha expression in breast cancer cells: prognostic and therapeutic implications |
| Funding Source: | NIH/NCI |
| Role: | Collaborator |
| ID: | 1 R01 CA143423 01 |
| Date: | 2009 - 2011 |
| Title: | The Cancer Metabolome: a study of similarities and differences |
| Funding Source: | NIH/NCI (Subcontract from University of Michigan) |
| Role: | Principal Investigator-MDACC |
| ID: | RFA-OD-09-003 |
| Date: | 2009 - 2011 |
| Title: | Novel Forms of Clustered Heat Maps for Pattern Recognition in Omic Data |
| Funding Source: | NIH/NCI |
| Role: | PI |
| ID: | 1 RC1 CA145800 01 |
| Date: | 2009 - 2011 |
| Title: | Biomarkers for Personalized Cancer Therapy |
| Funding Source: | NIH/NCI |
| Role: | CO-I |
| ID: | 1 RC2 CA148020 01 |
| Date: | 2009 - 2015 |
| Title: | An Integrative Pipeline for Analysis & Translational Application of TCGA Data (GDAC) |
| Funding Source: | NIH/NCI |
| Role: | PI |
| ID: | 5 U24 CA143883 04 |
| Date: | 2009 - 2012 |
| Title: | ARRA: An Integrative Pipeline for Analysis & Translational Application of TCGA Data (GDAC) - Admin Supplement |
| Funding Source: | NIH/NCI |
| Role: | PI |
| ID: | 3 U24 CA143883 02S1 |
| Date: | 2009 - 2012 |
| Title: | Comprehensive Analysis of Genetic Alterations in Oral Cancer |
| Funding Source: | NIH/NIDCR |
| Role: | Collaborator |
| ID: | 5 RC2 DE020958 02 |
| Date: | 2009 - 2014 |
| Title: | Molecular and Epidemiologic Characterization of Salivary Gland Carcinomas (PP-1) |
| Funding Source: | NIH/NIDCR |
| Role: | Co-Project Leader |
| ID: | 5 U01 DE019765 05 |
| Date: | 2009 - 2011 |
| Title: | The Acute Myelogenous Leukemia Integromics Atlas |
| Funding Source: | NIH/NCI |
| Role: | CO-I |
| ID: | 1 RC2 CA148419 01 |
| Date: | 2009 - 2011 |
| Title: | Development of multi-disciplinary center for molecular targets and signaling networks |
| Funding Source: | NIH/NCI |
| Role: | Subproject Leader |
| ID: | 1 RC2 CA148333 01 |
| Date: | 2009 - 2011 |
| Title: | The effect of biospecimen handling, shipping, storage and time on microRNA, protein, and serum stability and array results |
| Funding Source: | NIH/NCI |
| Role: | CO-I |
| ID: | 1 RC1 CA147862 01 |
| Date: | 2009 - 2012 |
| Title: | Autophagy in Ovarian Cancer: Molecular Analysis Core (PC-A) |
| Funding Source: | Ovarian Cancer Research Fund |
| Role: | Core Director |
| ID: | PPD/MDACC/01.08 03 |
| Date: | 2008 - 2013 |
| Title: | Mapping the epigenome of human hematopoietic cells |
| Funding Source: | NIH/NIEHS |
| Role: | CO-I |
| ID: | 1 U01 ES017157 01 |
| Date: | 2008 - 2011 |
| Title: | Biomarker-integrated Approaches of Targeted Therapy for Lung Cancer Elimination - AKA Battle II (PC-J) |
| Funding Source: | Cohen-Reinach Family Charitable Foundation |
| Role: | Collaborator |
| Date: | 2000 - 2003 |
| Title: | Design, Development, and Programming Support for National Cancer Institute's Laboratory of Molecular Pharmacology Bioinformatics Projects |
| Funding Source: | NIH/NCI |
| Role: | PI |
| ID: | NCI Delivery Order 48 |
| Date: | 1999 - 2010 |
| Title: | The University of Texas M. D. Anderson SPORE in Ovarian Cancer (PP-DPR-16) |
| Funding Source: | NIH/NCI |
| Role: | Project Leader |
| ID: | 5 P50 CA083639 10 |
| Title: | Lung SPORE: Targeting Lung Cancer Vulnerabilities |
| Funding Source: | UTMDACC |
| Role: | Internal Scientific Advisory Board |
Selected Publications
Peer-Reviewed Articles
- Rheinbay E, Nielsen MM, Abascal F, Wala JA, Shapira O, Tiao G, Hornshøj H, Hess JM, Juul RI, Lin Z, Feuerbach L, Sabarinathan R, Madsen T, Kim J, Mularoni L, Shuai S, Lanzós A, Herrmann C, Maruvka YE, Shen C, Amin SB, Bandopadhayay P, Bertl J, Boroevich KA, Busanovich J, Carlevaro-Fita J, Chakravarty D, Chan CWY, Craft D, Dhingra P, Diamanti K, Fonseca NA, Gonzalez-Perez A, Guo Q, Hamilton MP, Haradhvala NJ, Hong C, Isaev K, Johnson TA, Juul M, Kahles A, Kahraman A, Kim Y, Komorowski J, Kumar K, Kumar S, Lee D, Lehmann KV, Li Y, Liu EM, Lochovsky L, Park K, Pich O, Roberts ND, Saksena G, Schumacher SE, Sidiropoulos N, Sieverling L, Sinnott-Armstrong N, Stewart C, Tamborero D, Tubio JMC, Umer HM, Uusküla-Reimand L, Wadelius C, Wadi L, Yao X, Zhang CZ, Zhang J, Haber JE, Hobolth A, Imielinski M, Kellis M, Lawrence MS, von Mering C, Nakagawa H, Raphael BJ, Rubin MA, Sander C, Stein LD, Stuart JM, Tsunoda T, Wheeler DA, Johnson R, Reimand J, Gerstein M, Khurana E, Campbell PJ, López-Bigas N, Working Group PDAFI, Working Group PSV, Weischenfeldt J, Beroukhim R, Martincorena I, Pedersen JS, Getz G, Consortium P. Analyses of non-coding somatic drivers in 2,658 cancer whole genomes. Nature 578(7793):102-111, 2020. e-Pub 2020. PMID: 32025015.
- Gerstung M, Jolly C, Leshchiner I, Dentro SC, Gonzalez S, Rosebrock D, Mitchell TJ, Rubanova Y, Anur P, Yu K, Tarabichi M, Deshwar A, Wintersinger J, Kleinheinz K, Vázquez-García I, Haase K, Jerman L, Sengupta S, Macintyre G, Malikic S, Donmez N, Livitz DG, Cmero M, Demeulemeester J, Schumacher S, Fan Y, Yao X, Lee J, Schlesner M, Boutros PC, Bowtell DD, Zhu H, Getz G, Imielinski M, Beroukhim R, Sahinalp SC, Ji Y, Peifer M, Markowetz F, Mustonen V, Yuan K, Wang W, Morris QD, Working Group PE&H, Spellman PT, Wedge DC, Van Loo P, Consortium P. The evolutionary history of 2,658 cancers. Nature 578(7793):122-128, 2020. e-Pub 2020. PMID: 32025013.
- Li Y, Roberts ND, Wala JA, Shapira O, Schumacher SE, Kumar K, Khurana E, Waszak S, Korbel JO, Haber JE, Imielinski M, Working Group PSV, Weischenfeldt J, Beroukhim R, Campbell PJ, Consortium P. Patterns of somatic structural variation in human cancer genomes. Nature 578(7793):112-121, 2020. e-Pub 2020. PMID: 32025012.
- Core Group PT, Calabrese C, Davidson NR, Demircioglu D, Fonseca NA, He Y, Kahles A, Lehmann KV, Liu F, Shiraishi Y, Soulette CM, Urban L, Greger L, Li S, Liu D, Perry MD, Xiang Q, Zhang F, Zhang J, Bailey P, Erkek S, Hoadley KA, Hou Y, Huska MR, Kilpinen H, Korbel JO, Marin MG, Markowski J, Nandi T, Pan-Hammarström Q, Pedamallu CS, Siebert R, Stark SG, Su H, Tan P, Waszak SM, Yung C, Zhu S, Awadalla P, Creighton CJ, Meyerson M, Ouellette BFF, Wu K, Yang H, Working Group PT, Brazma A, Brooks AN, Göke J, Rätsch G, Schwarz RF, Stegle O, Zhang Z, Consortium P. Genomic basis for RNA alterations in cancer. Nature 578(7793):129-136, 2020. e-Pub 2020. PMID: 32025019.
- Alexandrov LB, Kim J, Haradhvala NJ, Huang MN, Tian Ng AW, Wu Y, Boot A, Covington KR, Gordenin DA, Bergstrom EN, Islam SMA, Lopez-Bigas N, Klimczak LJ, McPherson JR, Morganella S, Sabarinathan R, Wheeler DA, Mustonen V, Working Group PMS, Getz G, Rozen SG, Stratton MR, Consortium P. The repertoire of mutational signatures in human cancer. Nature 578(7793):94-101, 2020. e-Pub 2020. PMID: 32025018.
- Genomes Consortium IPAOW. Pan-Cancer analysis of whole genomes. Nature 578(7793):82-93, 2020. e-Pub 2020. PMID: 32025007.
- Wang F, Zhang S, Kim TB, Lin YY, Iqbal R, Wang Z, Mohanty V, Sircar K, Karam JA, Wendl MC, Meric-Bernstam F, Weinstein JN, Ding L, Mills GB, Chen K. Integrated transcriptomic-genomic tool Texomer profiles cancer tissues. Nat Methods 16(5):401-404, 2019. e-Pub 2019. PMID: 30988467.
- Corces MR, Granja JM, Shams S, Louie BH, Seoane JA, Zhou W, Silva TC, Groeneveld C, Wong CK, Cho SW, Satpathy AT, Mumbach MR, Hoadley KA, Robertson AG, Sheffield NC, Felau I, Castro MAA, Berman BP, Staudt LM, Zenklusen JC, Laird PW, Curtis C, Analysis Network CGA, Greenleaf WJ, Chang HY. The chromatin accessibility landscape of primary human cancers. Science 362(6413), 2018. e-Pub 2018. PMID: 30361341.
- Robertson AG, Kim J, Al-Ahmadie H, Bellmunt J, Guo G, Cherniack AD, Hinoue T, Laird PW, Hoadley KA, Akbani R, Castro MAA, Gibb EA, Kanchi RS, Gordenin DA, Shukla SA, Sanchez-Vega F, Hansel DE, Czerniak BA, Reuter VE, Su X, de Sa Carvalho B, Chagas VS, Mungall KL, Sadeghi S, Pedamallu CS, Lu Y, Klimczak LJ, Zhang J, Choo C, Ojesina AI, Bullman S, Leraas KM, Lichtenberg TM, Wu CJ, Schultz N, Getz G, Meyerson M, Mills GB, McConkey DJ, Network TR, Weinstein JN, Kwiatkowski DJ, Lerner SP. Comprehensive Molecular Characterization of Muscle-Invasive Bladder Cancer. Cell 174(4):1033, 2018. e-Pub 2018. PMID: 30096301.
- Kahles A, Lehmann KV, Toussaint NC, Hüser M, Stark SG, Sachsenberg T, Stegle O, Kohlbacher O, Sander C, Research Network CGA, Rätsch G. Comprehensive Analysis of Alternative Splicing Across Tumors from 8,705 Patients. Cancer Cell 34(2):211-224.e6, 2018. e-Pub 2018. PMID: 30078747.
- Wang Z, Yang B, Zhang M, Guo W, Wu Z, Wang Y, Jia L, Li S, Weinstein JN) CGARN(, Xie W, Yang D. lncRNA Epigenetic Landscape Analysis Identifies EPIC1 as an Oncogenic lncRNA that Interacts with MYC and Promotes Cell-Cycle Progression in Cancer. Cancer Cell 33(4):706-720.e9, 2018. e-Pub 2018. PMID: 29622465.
- Ding L, Bailey MH, Porta-Pardo E, Thorsson V, Colaprico A, Bertrand D, Gibbs DL, Weerasinghe A, Huang KL, Tokheim C, Cortés-Ciriano I, Jayasinghe R, Chen F, Yu L, Sun S, Olsen C, Kim J, Taylor AM, Cherniack AD, Akbani R, Suphavilai C, Nagarajan N, Stuart JM, Mills GB, Wyczalkowski MA, Vincent BG, Hutter CM, Zenklusen JC, Hoadley KA, Wendl MC, Shmulevich L, Lazar AJ, Wheeler DA, Getz G, Weinstein JN) CGARN(. Perspective on Oncogenic Processes at the End of the Beginning of Cancer Genomics. Cell 173(2):305-320.e10, 2018. e-Pub 2018. PMID: 29625049.
- Liu Y, Sethi NS, Hinoue T, Schneider BG, Cherniack AD, Sanchez-Vega F, Seoane JA, Farshidfar F, Bowlby R, Islam M, Kim J, Chatila W, Akbani R, Kanchi RS, Rabkin CS, Willis JE, Wang KK, McCall SJ, Mishra L, Ojesina AI, Bullman S, Pedamallu CS, Lazar AJ, Sakai R, Weinstein JN) CGARN(, Thorsson V, Bass AJ, Laird PW. Comparative Molecular Analysis of Gastrointestinal Adenocarcinomas. Cancer Cell 33(4):721-735.e8, 2018. e-Pub 2018. PMID: 29622466.
- Huang KL, Mashl RJ, Wu Y, Ritter DI, Wang J, Oh C, Paczkowska M, Reynolds S, Wyczalkowski MA, Oak N, Scott AD, Krassowski M, Cherniack AD, Houlahan KE, Jayasinghe R, Wang LB, Zhou DC, Liu D, Cao S, Kim YW, Koire A, McMichael JF, Hucthagowder V, Kim TB, Hahn A, Wang C, McLellan MD, Al-Mulla F, Johnson KJ, Weinstein JN) CGARN(, Lichtarge O, Boutros PC, Raphael B, Lazar AJ, Zhang W, Wendl MC, Govindan R, Jain S, Wheeler D, Kulkarni S, Dipersio JF, Reimand J, Meric-Bernstam F, Chen K, Shmulevich I, Plon SE, Chen F, Ding L. Pathogenic Germline Variants in 10,389 Adult Cancers. Cell 173(2):355-370.e14, 2018. e-Pub 2018. PMID: 29625052.
- Hoadley KA, Yau C, Hinoue T, Wolf DM, Lazar AJ, Drill E, Shen R, Taylor AM, Cherniack AD, Thorsson V, Akbani R, Bowlby R, Wong CK, Wiznerowicz M, Sanchez-Vega F, Robertson AG, Schneider BG, Lawrence MS, Noushmehr H, Malta TM, Weinstein JN) CGAN(, Stuart JM, Benz CC, Laird PW. Cell-of-Origin Patterns Dominate the Molecular Classification of 10,000 Tumors from 33 Types of Cancer. Cell 173(2):291-304.e6, 2018. e-Pub 2018. PMID: 29625048.
- Sanchez-Vega F, Mina M, Armenia J, Chatila WK, Luna A, La KC, Dimitriadoy S, Liu DL, Kantheti HS, Saghafinia S, Chakravarty D, Daian F, Gao Q, Bailey MH, Liang WW, Foltz SM, Shmulevich I, Ding L, Heins Z, Ochoa A, Gross B, Gao J, Zhang H, Kundra R, Kandoth C, Bahceci I, Dervishi L, Dogrusoz U, Zhou W, Shen H, Laird PW, Way GP, Greene CS, Liang H, Xiao Y, Wang C, Iavarone A, Berger AH, Bivona TG, Lazar AJ, Hammer GD, Giordano T, Kwong LN, McArthur G, Huang C, Tward AD, Frederick MJ, McCormick F, Meyerson M, Weinstein JN) CGARN(, Van Allen EM, Cherniack AD, Ciriello G, Sander C, Schultz N. Oncogenic Signaling Pathways in The Cancer Genome Atlas. Cell 173(2):321-337.e10, 2018. e-Pub 2018. PMID: 29625050.
- Bailey MH, Tokheim C, Porta-Pardo E, Sengupta S, Bertrand D, Weerasinghe A, Colaprico A, Wendl MC, Kim J, Reardon B, Ng PK, Jeong KJ, Cao S, Wang Z, Gao J, Gao Q, Wang F, Liu EM, Mularoni L, Rubio-Perez C, Nagarajan N, Cortés-Ciriano I, Zhou DC, Liang WW, Hess JM, Yellapantula VD, Tamborero D, Gonzalez-Perez A, Suphavilai C, Ko JY, Khurana E, Park PJ, Van Allen EM, Liang H, Group MW, Cancer Genome Atlas Research Network (including Weinstein JN, Lawrence MS, Godzik A, Lopez-Bigas N, Stuart J, Wheeler D, Getz G, Chen K, Lazar AJ, Mills GB, Karchin R, Ding L. Comprehensive Characterization of Cancer Driver Genes and Mutations. Cell 173(2):371-385.e18, 2018. e-Pub 2018. PMID: 29625053.
- Liu J, Lichtenberg T, Hoadley KA, Poisson LM, Lazar AJ, Cherniack AD, Kovatich AJ, Benz CC, Levine DA, Lee AV, Omberg L, Wolf DM, Shriver CD, Thorsson V, Weinstein JN) CGARN(, Hu H. An Integrated TCGA Pan-Cancer Clinical Data Resource to Drive High-Quality Survival Outcome Analytics. Cell 173(2):400-416.e11, 2018. e-Pub 2018. PMID: 29625055.
- Chen H, Li C, Peng X, Zhou Z, Weinstein JN, Research Network CGA, Liang H. A Pan-Cancer Analysis of Enhancer Expression in Nearly 9000 Patient Samples. Cell 173(2):386-399.e12, 2018. e-Pub 2018. PMID: 29625054.
- Malta TM, Sokolov A, Gentles AJ, Burzykowski T, Poisson L, Weinstein JN, Kaminska B, Huelsken J, Omberg L, Gevaert O, Colaprico A, Czerwinska P, Mazurek S, Mishra L, Heyn H, Krasnitz A, Godwin AK, Lazar AJ, Research Network CGA, Stuart JM, Hoadley KA, Laird PW, Noushmehr H, Wiznerowicz M. Machine Learning Identifies Stemness Features Associated with Oncogenic Dedifferentiation. Cell 173(2):338-54, 2018. e-Pub 2018. PMID: 29625051.
- Taylor AM, Shih J, Ha G, Gao GF, Zhang X, Berger AC, Schumacher SE, Wang C, Hu H, Liu J, Lazar AJ, Weinstein JN) CGARN(, Cherniack AD, Beroukhim R, Meyerson M. Genomic and Functional Approaches to Understanding Cancer Aneuploidy. Cancer Cell 33(4):676-689.e3, 2018. e-Pub 2018. PMID: 29622463.
- Berger AC, Korkut A, Kanchi RS, Hegde AM, Lenoir W, Liu W, Liu Y, Fan H, Shen H, Ravikumar V, Rao A, Schultz A, Li X, Sumazin P, Williams C, Mestdagh P, Gunaratne PH, Yau C, Bowlby R, Robertson AG, Tiezzi DG, Wang C, Cherniack AD, Godwin AK, Kuderer NM, Rader JS, Zuna RE, Sood AK, Lazar AJ, Ojesina AI, Adebamowo C, Adebamowo SN, Baggerly KA, Chen TW, Chiu HS, Lefever S, Liu L, MacKenzie K, Orsulic S, Roszik J, Shelley CS, Song Q, Vellano CP, Wentzensen N, Research Network CGA, Weinstein JN, Mills GB, Levine DA, Akbani R. A comprehensive Pan-Cancer molecular study of gynecologic and breast cancers. Cancer Cell 33(4):690-705.e9, 2018. e-Pub 2018. PMID: 29622464.
- Radovich M, Pickering CR, Felau I, Ha G, Zhang H, Jo H, Hoadley KA, Anur P, Zhang J, McLellan M, Bowlby R, Matthew T, Danilova L, Hegde AM, Kim J, Leiserson MDM, Sethi G, Lu C, Ryan M, Su X, Cherniack AD, Robertson G, Akbani R, Spellman P, Weinstein JN, Hayes DN, Raphael B, Lichtenberg T, Leraas K, Zenklusen JC, Atlas Network CG, Fujimoto J, Scapulatempo-Neto C, Moreira AL, Hwang D, Huang J, Marino M, Korst R, Giaccone G, Gokmen-Polar Y, Badve S, Rajan A, Ströbel P, Girard N, Tsao MS, Marx A, Tsao AS, Loehrer PJ. The integrated genomic landscape of thymic epithelial tumors. Cancer Cell 33(2):244-58, 2018. e-Pub 2018. PMID: 29438696.
- Weinstein JN) CGARN(. Comprehensive and Integrated Genomic Characterization of Adult Soft Tissue Sarcomas. Cell 171(4):950-965.e28, 2017. e-Pub 2017. PMID: 29100075.
- Robertson AG, Kim J, Al-Ahmadie H, Bellmunt J, Guo G, Cherniack AD, Hinoue T, Laird PW, Hoadley KA, Akbani R, Castro MAA, Gibb EA, Kanchi RS, Gordenin DA, Shukla SA, Sanchez-Vega F, Hansel DE, Czerniak BA, Reuter VE, Su X, de Sa Carvalho B, Chagas VS, Mungall KL, Sadeghi S, Pedamallu CS, Lu Y, Klimczak LJ, Zhang J, Choo C, Ojesina AI, Bullman S, Leraas KM, Lichtenberg TM, Wu CJ, Schultz N, Getz G, Meyerson M, Mills GB, McConkey DJ, Network TR, Weinstein JN, Kwiatkowski DJ, Lerner SP. Comprehensive Molecular Characterization of Muscle-Invasive Bladder Cancer. Cell 171(3):540-556.e25, 2017. e-Pub 2017. PMID: 28988769.
- Robertson AG, Shih J, Yau C, Gibb EA, Oba J, Mungall KL, Hess JM, Uzunangelov V, Walter V, Danilova L, Lichtenberg TM, Kucherlapati M, Kimes PK, Tang M, Penson A, Babur O, Akbani R, Bristow CA, Hoadley KA, Iype L, Chang MT, TCGA Research Network (including Weinstein JN, Cherniack AD, Benz C, Mills GB, Verhaak RGW, Griewank KG, Felau I, Zenklusen JC, Gershenwald JE, Schoenfield L, Lazar AJ, Abdel-Rahman MH, Roman-Roman S, Stern MH, Cebulla CM, Williams MD, Jager MJ, Coupland SE, Esmaeli B, Kandoth C, Woodman SE. Integrative Analysis Identifies Four Molecular and Clinical Subsets in Uveal Melanoma. Cancer Cell 32(2):204-220.e15, 2017. e-Pub 2017. PMID: 28810145.
- address: wheeler@bcmedu CGARNE, Weinstein JN) CGARN(. Comprehensive and Integrative Genomic Characterization of Hepatocellular Carcinoma. Cell 169(7):1327-1341.e23, 2017. e-Pub 2017. PMID: 28622513.
- Cherniack AD, Shen H, Walter V, Stewart C, Murray BA, Bowlby R, Hu X, Ling S, Soslow RA, Broaddus RR, Zuna RE, Robertson G, Laird PW, Kucherlapati R, Mills GB, Research Network CGA, Weinstein JN, Zhang J, Akbani R, Levine DA. Integrated Molecular Characterization of Uterine Carcinosarcoma. Cancer Cell 31(3):411-23, 2017. e-Pub 2017. PMID: 28292439.
- Fishbein L, Leshchiner I, Walter V, Danilova L, Robertson AG, Johnson AR, Lichtenberg TM, Murray BA, Ghayee HK, Else T, Ling S, Jefferys SR, de Cubas AA, Wenz B, Korpershoek E, Amelio AL, Makowski L, Rathmell WK, Gimenez-Roqueplo AP, Giordano TJ, Asa SL, Tischler AS, Weinstein JN) CGARN(, Pacak K, Nathanson KL, Wilkerson MD. Comprehensive Molecular Characterization of Pheochromocytoma and Paraganglioma. Cancer Cell 31(2):181-193, 2017. e-Pub 2017. PMID: 28162975.
- Weinstein JN) CGARN(. Integrated genomic and molecular characterization of cervical cancer. Nature, 2017. e-Pub 2017. PMID: 28112728.
- Cancer Genome Atlas Research Network (including Weinstein JN, Asan University AWG, BC Cancer Agency BC, Women’s Hospital BA, Institute B, University B, Reserve University CW, Institute DC, University D, Cancer Centre GP, School HM, Systems Biology IF, KU Leuven KU, Clinic M, Cancer Center MSK, Institute NC, Hospital NC, University S, Alabama UO, Michigan UO, North Carolina UO, Pittsburgh UO, Rochester UO, Southern California UO, Cancer Center UOTMA, Washington UO, Research Institute VA, University V, University W, Broad Institute GSC, St Louis WUI, Cancer Agency GCCB, Institute B, School HM, Hopkins University SKCCCAJ, North Carolina UO, Epigenome Center UOSC, Cancer Center UOTMA, Research Institute VA, Broad Institute GDAC, University: B, School HM, Systems Biology IF, Cancer Center MSK, Santa Cruz UOC, Cancer Center UOTMA, Genomics Consortium BCRI, Children’s Hospital RIAN, Biologic Services TSSA, Center AM, Bioscience A, Hospital BC, BioreclamationIVT, Clinic BM, Medical School CNU, Health System CC, Cureline, University D, University E, University E, of Medicine IUS, of Moldova IOO, Consortium IG, al E. Integrated genomic characterization of oesophageal carcinoma. Nature 541(7636):169-175, 2017. e-Pub 2017. PMID: 28052061.
- Zheng S, Cherniack AD, Dewal N, Moffitt RA, Danilova L, Murray BA, Lerario AM, Else T, Knijnenburg TA, Ciriello G, Kim S, Assie G, Morozova O, Akbani R, Shih J, Hoadley KA, Choueiri TK, Waldmann J, Mete O, Robertson AG, Wu HT, Raphael BJ, Shao L, Meyerson M, Demeure MJ, Beuschlein F, Gill AJ, Sidhu SB, Almeida MQ, Fragoso MC, Cope LM, Kebebew E, Habra MA, Whitsett TG, Bussey KJ, Rainey WE, Asa SL, Bertherat J, Fassnacht M, Wheeler DA, Cancer Genome Atlas Research Network (including Weinstein JN, Hammer GD, Giordano TJ, Verhaak RG. Comprehensive Pan-Genomic Characterization of Adrenocortical Carcinoma. Cancer Cell 30(2):363, 2016. e-Pub 2016. PMID: 27505681.
- Ceccarelli M, Barthel FP, Malta TM, Sabedot TS, Salama SR, Murray BA, Morozova O, Newton Y, Radenbaugh A, Pagnotta SM, Anjum S, Wang J, Manyam G, Zoppoli P, Ling S, Rao AA, Grifford M, Cherniack AD, Zhang H, Poisson L, Carlotti CG, Tirapelli DP, Rao A, Mikkelsen T, Lau CC, Yung WK, Rabadan R, Huse J, Brat DJ, Lehman NL, Barnholtz-Sloan JS, Zheng S, Hess K, Rao G, Meyerson M, Beroukhim R, Cooper L, Akbani R, Wrensch M, Haussler D, Aldape KD, Laird PW, Gutmann DH, Weinstein JN) TRN(, Noushmehr H, Iavarone A, Verhaak RG. Molecular Profiling Reveals Biologically Discrete Subsets and Pathways of Progression in Diffuse Glioma. Cell 164(3):550-63, 2016. e-Pub 2016. PMID: 26824661.
- Research Network CGA, Linehan WM, Spellman PT, Ricketts CJ, Creighton CJ, Fei SS, Davis C, Wheeler DA, Murray BA, Schmidt L, Vocke CD, Peto M, Al Mamun AA, Shinbrot E, Sethi A, Brooks S, Rathmell WK, Brooks AN, Hoadley KA, Robertson AG, Brooks D, Bowlby R, Sadeghi S, Shen H, Weisenberger DJ, Bootwalla M, Baylin SB, Laird PW, Cherniack AD, Saksena G, Haake S, Li J, Liang H, Lu Y, Mills GB, Akbani R, Leiserson MD, Raphael BJ, Anur P, Bottaro D, Albiges L, Barnabas N, Choueiri TK, Czerniak B, Godwin AK, Hakimi AA, Ho TH, Hsieh J, Ittmann M, Kim WY, Krishnan B, Merino MJ, Mills Shaw KR, Reuter VE, Reznik E, Shelley CS, Shuch B, Signoretti S, Srinivasan R, Tamboli P, Thomas G, Tickoo S, Burnett K, Crain D, Gardner J, Lau K, Mallery D, Morris S, Paulauskis JD, Penny RJ, Shelton C, Shelton WT, Sherman M, Thompson E, Yena P, Avedon MT, Bowen J, Gastier-Foster JM, Gerken M, Leraas KM, Lichtenberg TM, Ramirez NC, Santos T, Wise L, Zmuda E, Demchok JA, Felau I, Hutter CM, Sheth M, Sofia HJ, Tarnuzzer R, Wang Z, Yang L, Zenklusen JC, Zhang J, Ayala B, Baboud J, Chudamani S, Liu J, Lolla L, Naresh R, Pihl T, Sun Q, Wan Y, Wu Y, Ally A, Balasundaram M, Balu S, Beroukhim R, Bodenheimer T, Buhay C, Butterfield YS, Carlsen R, Carter SL, Chao H, Chuah E, Clarke A, Covington KR, Dahdouli M, Dewal N, Dhalla N, Doddapaneni HV, Drummond JA, Gabriel SB, Gibbs RA, Guin R, Hale W, Hawes A, Hayes DN, Holt RA, Hoyle AP, Jefferys SR, Jones SJ, Jones CD, Kalra D, Kovar C, Lewis L, Li J, Ma Y, Marra MA, Mayo M, Meng S, Meyerson M, Mieczkowski PA, Moore RA, Morton D, Mose LE, Mungall AJ, Muzny D, Parker JS, Perou CM, Roach J, Schein JE, Schumacher SE, Shi Y, Simons JV, Sipahimalani P, Skelly T, Soloway MG, Sougnez C, Tam A, Tan D, Thiessen N, Veluvolu U, Wang M, Wilkerson MD, Wong T, Wu J, Xi L, Zhou J, Bedford J, Chen F, Fu Y, Gerstein M, Haussler D, Kasaian K, Lai P, Ling S, Radenbaugh A, Van Den Berg D, Weinstein JN, Zhu J, Albert M, Alexopoulou I, Andersen JJ, al E. Comprehensive Molecular Characterization of Papillary Renal-Cell Carcinoma. N Engl J Med 374(2):135-45, 2016. e-Pub 2016. PMID: 26536169.
- Zhou W, Chen T, Chong Z, Rohrdanz MA, Melott JM, Wakefield C, Zeng J, Weinstein JN, Meric-Bernstam F, Mills GB, Chen K. TransVar: a multilevel variant annotator for precision genomics. Nat Methods 12(11):1002-3, 2015. e-Pub 2015. PMID: 26513549.
- Ciriello G, Gatza ML, Beck AH, Wilkerson MD, Rhie SK, Pastore A, Zhang H, McLellan M, Yau C, Kandoth C, Bowlby R, Shen H, Hayat S, Fieldhouse R, Lester SC, Tse GM, Factor RE, Collins LC, Allison KH, Chen YY, Jensen K, Johnson NB, Oesterreich S, Mills GB, Cherniack AD, Robertson G, Benz C, Sander C, Laird PW, Hoadley KA, King TA, Weinstein JN) TRN(, Perou CM. Comprehensive Molecular Portraits of Invasive Lobular Breast Cancer. Cell 163(2):506-19, 2015. e-Pub 2015. PMID: 26451490.
- Skoulidis F, Byers LA, Diao L, Papadimitrakopoulou VA, Tong P, Izzo J, Behrens C, Kadara H, Parra ER, Canales JR, Zhang J, Giri U, Gudikote J, Cortez MA, Yang C, Fan Y, Peyton M, Girard L, Coombes KR, Toniatti C, Heffernan TP, Choi M, Frampton GM, Miller V, Weinstein JN, Herbst RS, Wong KK, Zhang J, Sharma P, Mills GB, Hong WK, Minna JD, Allison JP, Futreal A, Wang J, Wistuba II, Heymach JV. Co-occurring genomic alterations define major subsets of KRAS - mutant lung adenocarcinoma with distinct biology, immune profiles, and therapeutic vulnerabilities. Cancer Discov 5(8):860-77, 2015. e-Pub 2015. PMID: 26069186.
- Research Network CGA, Brat DJ, Verhaak RG, Aldape KD, Yung WK, Salama SR, Cooper LA, Rheinbay E, Miller CR, Vitucci M, Morozova O, Robertson AG, Noushmehr H, Laird PW, Cherniack AD, Akbani R, Huse JT, Ciriello G, Poisson LM, Barnholtz-Sloan JS, Berger MS, Brennan C, Colen RR, Colman H, Flanders AE, Giannini C, Grifford M, Iavarone A, Jain R, Joseph I, Kim J, Kasaian K, Mikkelsen T, Murray BA, O'Neill BP, Pachter L, Parsons DW, Sougnez C, Sulman EP, Vandenberg SR, Van Meir EG, von Deimling A, Zhang H, Crain D, Lau K, Mallery D, Morris S, Paulauskis J, Penny R, Shelton T, Sherman M, Yena P, Black A, Bowen J, Dicostanzo K, Gastier-Foster J, Leraas KM, Lichtenberg TM, Pierson CR, Ramirez NC, Taylor C, Weaver S, Wise L, Zmuda E, Davidsen T, Demchok JA, Eley G, Ferguson ML, Hutter CM, Mills Shaw KR, Ozenberger BA, Sheth M, Sofia HJ, Tarnuzzer R, Wang Z, Yang L, Zenklusen JC, Ayala B, Baboud J, Chudamani S, Jensen MA, Liu J, Pihl T, Raman R, Wan Y, Wu Y, Ally A, Auman JT, Balasundaram M, Balu S, Baylin SB, Beroukhim R, Bootwalla MS, Bowlby R, Bristow CA, Brooks D, Butterfield Y, Carlsen R, Carter S, Chin L, Chu A, Chuah E, Cibulskis K, Clarke A, Coetzee SG, Dhalla N, Fennell T, Fisher S, Gabriel S, Getz G, Gibbs R, Guin R, Hadjipanayis A, Hayes DN, Hinoue T, Hoadley K, Holt RA, Hoyle AP, Jefferys SR, Jones S, Jones CD, Kucherlapati R, Lai PH, Lander E, Lee S, Lichtenstein L, Ma Y, Maglinte DT, Mahadeshwar HS, Marra MA, Mayo M, Meng S, Meyerson ML, Mieczkowski PA, Moore RA, Mose LE, Mungall AJ, Pantazi A, Parfenov M, Park PJ, Parker JS, Perou CM, Protopopov A, Ren X, Roach J, Sabedot TS, Schein J, Schumacher SE, Seidman JG, Seth S, Shen H, Simons JV, Sipahimalani P, Soloway MG, Song X, Sun H, Tabak B, Tam A, Tan D, Tang J, Thiessen N, Triche T, Van Den Berg DJ, Veluvolu U, Waring S, Weisenberger DJ, Wilkerson MD, Wong T, Wu J, Xi L, Xu AW, Yang L, Zack TI, Zhang J, Aksoy BA, Arachchi H, Benz C, Bernard B, Carlin D, Cho J, DiCara D, Frazer S, Fuller GN, Gao J. Comprehensive, Integrative Genomic Analysis of Diffuse Lower-Grade Gliomas. N Engl J Med 372(26):2481-98, 2015. e-Pub 2015. PMID: 26061751.
- Hoadley KA, Yau C, Wolf DM, Cherniack AD, Tamborero D, Ng S, Leiserson MD, Niu B, McLellan MD, Uzunangelov V, Zhang J, Kandoth C, Akbani R, Shen H, Omberg L, Chu A, Margolin AA, Van't Veer LJ, Lopez-Bigas N, Laird PW, Raphael BJ, Ding L, Robertson AG, Byers LA, Mills GB, Weinstein JN, Van Waes C, Chen Z, Collisson EA, Research Network CGA, Benz CC, Perou CM, Stuart JM. Multiplatform Analysis of 12 Cancer Types Reveals Molecular Classification within and across Tissues of Origin. Cell 158(4):929-44, 2014. e-Pub 2014. PMID: 25109877.
- Yuan Y, Van Allen EM, Omberg L, Wagle N, Amin-Mansour A, Sokolov A, Byers LA, Xu Y, Hess KR, Diao L, Han L, Huang X, Lawrence MS, Weinstein JN, Stuart JM, Mills GB, Garraway LA, Margolin AA, Getz G, Liang H. Assessing the clinical utility of cancer genomic and proteomic data across tumor types. Nat Biotechnol 32(7):644-52, 2014. e-Pub 2014. PMID: 24952901.
- Weinstein JN, Lorenzi PL. Discrepancies in drug sensitivity. Nature 504(7480):381-3, 2013. e-Pub 2013. PMID: 24284624.
- Li J, Lu Y, Akbani R, Ju Z, Roebuck PL, Liu W, Yang JY, Broom BM, Verhaak RG, Kane DW, Wakefield C, Weinstein JN, Mills GB, Liang H. TCPA: A Resource for Cancer Functional Proteomics Data. Nat Methods 10(11):1046-7, 2013. e-Pub 2013. PMID: 24037243.
- Brennan CW, Verhaak RG, McKenna A, Campos B, Noushmehr H, Salama SR, Zheng S, Chakravarty D, Sanborn JZ, Berman SH, Beroukhim R, Bernard B, Wu CJ, Genovese G, Shmulevich I, Barnholtz-Sloan J, Zou L, Vegesna R, Shukla SA, Ciriello G, Yung WK, Zhang W, Sougnez C, Mikkelsen T, Aldape K, Bigner DD, Van Meir EG, Prados M, Sloan A, Black KL, Eschbacher J, Finocchiaro G, Friedman W, Andrews DW, Guha A, Iacocca M, O'Neill BP, Foltz G, Myers J, Weisenberger DJ, Penny R, Kucherlapati R, Perou CM, Hayes DN, Gibbs R, Marra M, Mills GB, Lander E, Spellman P, Wilson R, Sander C, Weinstein JN, Meyerson M, Gabriel S, Laird PW, Haussler D, Getz G, Chin L, Network TR. The somatic genomic landscape of glioblastoma. Cell 155(2):462-77, 2013. e-Pub 2013. PMID: 24120142.
- Pickering CR, Zhang J, Yoo SY, Bengtsson L, Moorthy S, Neskey DM, Zhao M, Ortega Alves MV, Chang K, Drummond J, Cortez E, Xie TX, Zhang D, Chung W, Issa JP, Zweidler-McKay PA, Wu X, El-Naggar AK, Weinstein JN, Wang J, Muzny DM, Gibbs RA, Wheeler DA, Myers JN, Frederick MJ. Integrative genomic characterization of oral squamous cell carcinoma identifies frequent somatic drivers. Cancer Discov 3(7):770-81, 2013. e-Pub 2013. PMID: 23619168.
- Cancer Genome Atlas Research Network (including Weinstein JN, Kandoth C, Schultz N, Cherniack AD, Akbani R, Liu Y, Shen H, Robertson AG, Pashtan I, Shen R, Benz CC, Yau C, Laird PW, Ding L, Zhang W, Mills GB, Kucherlapati R, Mardis ER, Levine DA. Integrated genomic characterization of endometrial carcinoma. Nature 497(7447):67-73, 2013. e-Pub 2013. PMID: 23636398.
- Weinstein JN) CGARN(. Genomic and epigenomic landscapes of adult de novo acute myeloid leukemia. NEJM 368(22):2059-74, 2013. e-Pub 2013. PMID: 23634996.
- statistical analyses) CGAN(WJF. Comprehensive molecular portraits of human breast tumours. Nature 490(7418):61-70, 2012. e-Pub 2012. PMID: 23000897.
- Research Network CGA, Hammerman PS, Hayes DN, Wilkerson MD, Schultz N, Bose R, Chu A, Collisson EA, Cope L, Creighton CJ, Getz G, Herman JG, Johnson BE, Kucherlapati R, Ladanyi M, Maher CA, Robertson G, Sander C, Shen R, Sinha R, Sivachenko A, Thomas RK, Travis WD, Tsao MS, Writing Committee) WJ(SAA, Wigle DA, Baylin SB, Govindan R, Meyerson M. Comprehensive genomic characterization of squamous cell lung cancers. Nature 489(7417):519-25, 2012. e-Pub 2012. PMID: 22960745.
- Byers LA, Wang J, Nilsson MB, Fujimoto J, Saintigny P, Yordy J, Giri U, Peyton M, Fan YH, Diao L, Masrorpour F, Shen L, Liu W, Duchemann B, Tumula P, Bhardwaj V, Welsh J, Weber S, Glisson BS, Kalhor N, Wistuba II, Girard L, Lippman SM, Mills GB, Coombes KR, Weinstein JN, Minna JD, Heymach JV. Proteomic profiling identifies dysregulated pathways in small cell lung cancer and novel therapeutic targets including PARP1. Cancer Discov 2(9):798-811, 2012. e-Pub 2012. PMID: 22961666.
- Atlas Network CG. Comprehensive molecular characterization of human colon and rectal cancer. Nature 487(7407):330-7, 2012. e-Pub 2012. PMID: 22810696.
- Weinstein JN. Drug discovery: Cell lines battle cancer. Nature 483(7391):544-5, 2012. e-Pub 2012. PMID: 22460893.
- Agrawal N, Frederick MJ, Pickering CR, Bettegowda C, Chang K, Li RJ, Fakhry C, Xie TX, Zhang J, Wang J, Zhang N, El-Naggar AK, Jasser SA, Weinstein JN, Treviño L, Drummond JA, Muzny DM, Wu Y, Wood LD, Hruban RH, Westra WH, Koch WM, Califano JA, Gibbs RA, Sidransky D, Vogelstein B, Velculescu VE, Papadopoulos N, Wheeler DA, Kinzler KW, Myers JN. Exome Sequencing of Head and Neck Squamous Cell Carcinoma Reveals Inactivating Mutations in NOTCH1. Science 333(6046):1154-7, 2011. e-Pub 2011. PMID: 21798897.
- Weinstein JN. A postgenomic visual icon. Science 319(5871):1772-3, 2008. e-Pub 2008. PMID: 18369130.
- Weinstein JN, Leitz FB. Electric Power from Differences in Salinity: The Dialytic Battery. Science 191(4227):557-559, 1976. e-Pub 1976. PMID: 17792805.
Book Chapters
- Weinstein, JN. Cancer Bioinformatics. In: Cancer Medicine. 10th Edition. John Wiley, 2023.
- Weinstein JN, Ralston E, Leserman LD, Klausner RD, Dragsten P, Blumenthal R. Self-quenching of carboxyfluorescein Fluorescence: Uses in studying lioposome stability and liposome-cell interaction. In: Liposome Technology. CRC Press, 183-204, 2018.
- Weinstein JN. Cancer Bioinformatics. In: Cancer Medicine, 9th Edition. John Wiley, 2017.
- Ben-Dor A, Lipson D, Tsalenko A, Baumbusch L, Barrett MM, Weinstein JN, Reimers M, A-L B, Yakhini Z. Framework for Identifying Common Aberrations in DNA Copy Number Data. In: RECOMB 2007. Springer Berlin, 122-36, 2007.
- Weinstein JN. Linking drugs and genes: Pharmacogenomics, pharmacoproteomics, bioinformatics, and the NCI-60. In: Oncogenomics: Molecular Approaches to Cancer. John Wiley & Sons, 117-37, 2004.
- Viswanadhan VN, Ghose AK, Kiselyov A, Weinstein JN, Wendeloski JJ. Knowledge-based approaches for the design of small molecule libraries for drug discovery. In: Combinatorial library design and evaluation: Principles, software tools, and Applications in Drug Discovery. Marcel-Dekker, 8888, 2001.
- Weinstein JN, Waltham M, Reinhold W, Lee JK, Smith LH, Andrews D, Tanabe L, Zhou Y, Myers TG, Buolamwini JK, Scherf U. The current revolution in cancer drug discovery: Genomics, proteomics, and bioinformatics. In: Fighting against Cancer: Progress and New Hopes, 21-36, 2000.
- Casciari J, Sato H, Durum, SK, Fiege J, Weinstein JN. Tabular lexicon of cytokine structure and function. In: Cancer Chemotherapy and Biotherapy: Principles and Practice. Lippincott-Raven, 787-810, 1996.
- Casciari J, Sato H, Durum SK, Fiege J, Weinstein JN. Reference databases of cytokine structure and function. In: Chemotherapy and Biological Response Modifiers Annual 16. Elsevier, 315-46, 1996.
- Chabner BA, Weinstein JN, Paull KD, Grever MR. Cell line-based screening for new anticancer drugs. In: Cancer Treatment an Update. Springer-Verlag France, 10-6, 1994.
- Weinstein JN. Neural networks and predictive statistics in drug discovery. In: Handbook for the International Forum on Advances in Screening Technology and Data Management, 79-83, 1994.
- Weinstein JN, Bunow, B. COMBO: New concepts and methods for designing and analyzing experiments on combination therapy. In: Combination Therapies: Biological Response Modifiers in the Treatment of Cancer and Infectious Diseases. Plenum Press, 29-38, 1992.
- Weinstein JN, Fujimore K. Antibody-mediated drug delivery. In: Protein Design and the Development of New Therapeutics and Vaccines. Plenum Press, 359-70, 1990.
- Weinstein JN, Fujimori K. The pharmacokinetics of monoclonal antibodies and derived peptides. In: Preclinical Evaluation of Peptides and Recombinant Proteins. Skogs Grafiska AB, 35-41, 1990.
- Weinstein JN, Fujimori K. Predictive Pharmacology of monoclonal antibodies. In: Cancer Therapy: New Trends. Springer-Verlag, 197-9, 1989.
- Weinstein JN. Immunolymphoscintigraphy and other regional applications of monoclonal antibodies. In: Antibodies in Radiodiagnosis and Therapy. CRC Press, 153-67, 1988.
- Weinstein JN, Black CDV, Holton III OD, Covell DG, Parker RJ, Mulshine JL, Lotze MT, Carrasquillo J, Eger RR, Lewis A, Sm L, Keenan AM. Delivery of monoclonal antibodies to lymph nodes via the lymphatics. In: The Pharmacology and Toxicology of Proteins. Alar R. Liss, 75-89, 1987.
- Weinstein JN. Liposomes in the diagnosis and treatment of cancer. In: Liposomes. Marcel Dekker, 277-338, 1987.
- Weinstein JN, Covell DG, Barbet J, Eger RR, Holton III OD, Talley MJ, Parker RJ, black CDV. The pharmacology of monoclonal antibodies. In: Membrane-mediated Cytotoxicity. Alan R. Liss, 279-89, 1987.
- Weinstein JN, Blumenthal R, Klausner RD. Carboxyfluorescein leakage assay for lipoprotein-liposome interaction. In: Methods in Enzymol. A. Academic Press, 657-68, 1986.
- Weinstein JN, Leserman LD. Liposomes as drug carriers in cancer chemotherapy. In: The International Encyclopedia of Pharmacology and Therapeutics: Membrane Transport of Anti-neoplastic Agents. Pergamon Press, 169-94, 1986.
- Weinstein JN, Black CDV, Keenan AM, Holton III OD, Larson SM, Sieber SM, Covell DG, Carrasquillo J, Barbet J, Parker RJ. Use of monoclonal antibodies for detection of lymph node metastases. In: Monoclonal Antibodies in Cancer Therapy. Alan R. Liss, 473-88, 1986.
- Weinstein JN, Black CDV, Barbet J, Eger RR, Parker RJ, Holton III OD, Mulshine JL, Keenan AM, Larson SM, Carrasquillo JA, Sieber SM, Covell DG. Selected issues in the pharmacology of monoclonal antibodies. In: Site-specific Drug Delivery: Cell Biology, Medicinal and Pharmaceutical Aspects. John Wiley, 81-91, 1986.
- Weinstein JN, Keenan AM, Holton III OD, Covell DG, Sieber SM, Black CDV, Barbet J, Parker RJ. Use of monoclonal antibodies to detect metastases of solid tumors in lumph nodes. In: Monoclonal Antibodies and Breast Cancer. Martinus Nijhof, 218-32, 1985.
- Weinstein JN, Holton OD, Black CDV, Keenan AM, Covell DG, Spaulding GF, Barbet J, Steller MA, Sieber SM, Talley MJ, Parker RJ. Monoclonal Antitumor antibodies in the lumphatics. In: 1985 Year Book of Cancer. Year Book Medical Publishers, 264-6, 1985.
- Blumenthal R, Kempf C, Renswoude JV, Weinstein JN, Klausner RD. Voltage-dependent orientation of membrane proteins. In: Protein Transport and Secretion. Alan R. Liss, 1-13, 1984.
- Weinstein JN, Leserman LD, Henkart PA, Blumental R. Antibody-mediated targeting of liposomes. In: Targeting of Drugs. Plenum, 185-202, 1982.
- Magin RL, Weinstein JN. Delivery of drugs in temperature-sensitive liposomes. In: Targeting of Drugs. Plenum, 203-21, 1982.
- Magin RL, Weinstein JN. Selective delivery of drugs in "temperature-sensitive" liposomes. In: Liposomes and Immunobiology. Elsevier, 315-25, 1980.
- Leserman LD, Weinstein JN. Receptor mediated binding and endocytosis of drug-containing liposomes by tumor cells. In: Liposomes and Immunobiology. Elsevier, 241-51, 1980.
- Yatvin MB, Weinstein JN, Dennis WH, Blumenthal R. Use of hyperthermia to promote selective local release of drugs from liposomes. In: Proceedings of the Conference on Clinical Prospects for Hypoxic Cell Sensitizers and Hyperthermia. Madison Printing and Publishing Company, 105-12, 1978.
Patents
- Therapeutic Asparaginases. Patent Number: 14/917,934.
- Materials and Methods Directed to Asparagine Synthetase and Asparaginease Therapies. Patent Number: Patent #9181552.
- Treatment of Diagnosis by Endoscopic Administration into the Lymphatics. Patent Number: 9999.
- Restriction Display (RD-PCR) of Differentially Expressed mRNAs. Patent Number: 9999.
Patient Reviews
CV information above last modified March 31, 2026