Ken-Pin Hwang, Ph.D.
Department of Imaging Physics, Division of Diagnostic Imaging
Present Title & Affiliation
Primary Appointment
Associate Professor, Department of Imaging Physics, Division of Diagnostic Imaging, The University of Texas MD Anderson Cancer Center, Houston, TX
Dual/Joint/Adjunct Appointment
Associate Member, The University of Texas School of Biomedical Sciences, Houston, TX
Research Interests
MR for treatment planning | geometric accuracy and assessment for MRI | synthetic MR imaging | pulse sequence design and image reconstruction
Education & Training
Degree-Granting Education
2002 | Case Western Reserve University, Cleveland, OH, USA, PHD, Biomedical Engineering |
2000 | Case Western Reserve University, Cleveland, OH, USA, MS, Biomedical Engineering |
1996 | University of California, Berkeley, CA, USA, BS, Computer Science |
Board Certifications
2017 | American Board of Medical Physics, Magnetic Resonance Imaging Physics |
Honors & Awards
2014 | Innovation Competition Award, GE Healthcare |
1997 | Graduate Fellowship Award, Case Western Reserve University |
Professional Memberships
Selected Publications
Peer-Reviewed Articles
- Fujita S, Hagiwara A, Takei N, Hwang KP, Fukunaga I, Kato S, Andica C, Kamagata K, Yokoyama K, Hattori N, Abe O, Aoki S. Accelerated Isotropic Multiparametric Imaging by High Spatial Resolution 3D-QALAS With Compressed Sensing: A Phantom, Volunteer, and Patient Study. Invest Radiol 56(5):292-300, 2021. PMID: 33273376.
- Abdelhafez AH, Musall BC, Adrada BE, Hess K, Son JB, Hwang KP, Candelaria RP, Santiago L, Whitman GJ, Le-Petross HT, Moseley TW, Arribas E, Lane DL, Scoggins ME, Leung JWT, Mahmoud HS, White JB, Ravenberg EE, Litton JK, Valero V, Wei P, Thompson AM, Moulder SL, Pagel MD, Ma J, Yang WT, Rauch GM. Tumor necrosis by pretreatment breast MRI: association with neoadjuvant systemic therapy (NAST) response in triple-negative breast cancer (TNBC). Breast Cancer Res Treat 185(1):1-12, 2021. e-Pub 2020. PMID: 32920733.
- Mitchell DP, Hwang KP, Bankson JA, Stafford RJ, Banerjee S, Takei N, Fuentes DT. An Information Theory Model for Optimizing Quantitative Magnetic Resonance Imaging Acquisitions. Phys Med Biol 66(22). e-Pub 2020. PMID: 32947269.
- Slagowski JM, Ding Y, Aima M, Wen Z, Fuller CD, Chung C, Debnam JM, Hwang KP, Kadbi M, Szklaruk J, Wang J. A modular phantom and software to characterize 3D geometric distortion in MRI. Phys Med Biol 65(19):195008. e-Pub 2020. PMID: 32531763.
- Fujita S, Hagiwara A, Otsuka Y, Hori M, Takei N, Hwang KP, Irie R, Andica C, Kamagata K, Akashi T, Kunishima Kumamaru K, Suzuki M, Wada A, Abe O, Aoki S. Deep Learning Approach for Generating MRA Images From 3D Quantitative Synthetic MRI Without Additional Scans. Invest Radiol 55(4):249-256, 2020. PMID: 31977603.
- Qayyum A, Hwang KP, Stafford J, Verma A, Maru DM, Sandesh S, Sun J, Pestana RC, Avritscher R, Hassan MM, Amin H, Rashid A, Wistuba II, Ehman RL, Ma J, Kaseb AO. Immunotherapy response evaluation with magnetic resonance elastography (MRE) in advanced HCC. J Immunother Cancer 7(1):329, 2019.
- Fahrenholtz S, Guo C, MacLellan C, Yung JP, Hwang KP, Layman R, Stafford RJ, Cressman E. Temperature mapping of exothermic in situ chemistry: imaging of thermoembolization via MR. International Journal of Hyperthermia 36(1):730-738, 2019. PMID: 31362538.
- Yan Y, Yang J, Beddar S, Ibbott G, Wen Z, Court LE, Hwang KP, Kadbi M, Krishnan S, Fuller CD, Frank SJ, Yang J, Balter P, Kudchadker RJ, Wang J. A methodology to investigate the impact of image distortions on the radiation dose when using magnetic resonance images for planning. Phys Med Biol 63(8):085005, 2018. e-Pub 2018. PMID: 29528037.
- Wang J, Yung J, Kadbi M, Hwang K, Ding Y, Ibbott GS. Assessment of image quality and scatter and leakage radiation of an integrated MR-LINAC system. Med Phys 45(3):1204-1209, 2018. e-Pub 2018. PMID: 29363770.
- Price RG, Knight RA, Hwang KP, Bayram E, Nejad-Davarani SP, Glide-Hurst CK. Optimization of a novel large field of view distortion phantom for MR-only treatment planning. J Appl Clin Med Phys 18(4):51-61, 2017. e-Pub 2017. PMID: 28497476.
- Weavers PT, Tao S, Trzasko JD, Shu Y, Tryggestad EJ, Gunter JL, McGee KP, Litwiller DV, Hwang KP, Bernstein MA. Image-based gradient non-linearity characterization to determine higher-order spherical harmonic coefficients for improved spatial position accuracy in magnetic resonance imaging. Magn Reson Imaging 38:54-62, 2017. e-Pub 2016. PMID: 28034637.
- Son JB, Hwang KP, Madewell JE, Bayram E, Hazle JD, Low RN, Ma J. A flexible fast spin echo triple-echo Dixon technique. Magn Reson Med 77(3):1049-1057, 2017. e-Pub 2016. PMID: 26982770.
- Wang J, Weygand J, Hwang KP, Mohamed AS, Ding Y, Fuller CD, Lai SY, Frank SJ, Zhou J. Magnetic Resonance Imaging of Glucose Uptake and Metabolism in Patients with Head and Neck Cancer. Sci Rep 6:30618, 2016. e-Pub 2016. PMID: 27461165.
- Hui C, Wen Z, Stemkens B, Tijssen RH, van den Berg CA, Hwang KP, Beddar S. 4D MR imaging using robust internal respiratory signal. Phys Med Biol 61(9):3472–3487, 2016. e-Pub 2016. PMID: 27049817.
- Torfeh T, Hammoud R, Perkins G, McGarry M, Aouadi S, Celik A, Hwang KP, Stancanello J, Petric P, Al-Hammadi N. Characterization of 3D geometric distortion of Magnetic Resonance Imaging scanners commissioned for Radiation Therapy planning. Magn Reson Imaging 34(5):645–653, 2016. e-Pub 2016. PMID: 26795695.
- Huang SY, Abdelsalam ME, Harmoush S, Ensor JE, Chetta JA, Hwang KP, Stafford RJ, Madoff DC, Avritscher R. Evaluation of liver fibrosis and hepatic venous pressure gradient with MR elastography in a novel swine model of cirrhosis. J Magn Reson Imaging 39(3):590-7, 2014. e-Pub 2013. PMID: 24532376.
- Lin JS, Hwang KP, Jackson EF, Hazle JD, Stafford RJ, Taylor BA. Multiparametric fat-water separation method for fast chemical-shift imaging guidance of thermal therapies. Med Phys 40(10):103302, 2013. PMID: 24089932.
- Taylor BA, Elliott AM, Hwang KP, Hazle JD, Stafford RJ. Correlation between the temperature dependence of intrinsic MR parameters and thermal dose measured by a rapid chemical shift imaging technique. NMR Biomed 24(10):1414-21, 2011. e-Pub 2011. PMID: 21721063.
- Dogan BE, Ma J, Hwang K, Liu P, Yang WT. T1-weighted 3D dynamic contrast-enhanced MRI of the breast using a dual-echo Dixon technique at 3 T. J Magn Reson Imaging 34(4):842-51, 2011. e-Pub 2011. PMID: 21769987.
- Taylor BA, Elliott AM, Hwang KP, Shetty A, Hazle JD, Stafford RJ. Measurement of temperature dependent changes in bone marrow using a rapid chemical shift imaging technique. J Magn Reson Imaging 33(5):1128-35, 2011. PMID: 21509871.
- Shi K, Low R, Hwang KP, Bao S, Ma J. Flow compensation for the fast spin echo triple-echo Dixon sequence. Magn Reson Imaging 29(2):293-9, 2011. e-Pub 2010. PMID: 20863642.
- Ahmad M, Liu Y, Slavens ZW, Low R, Merkle E, Hwang KP, Vu A, Ma J. A method for automatic identification of water and fat images from a symmetrically sampled dual-echo Dixon technique. Magn Reson Imaging 28(3):427-33, 2010. e-Pub 2010. PMID: 20061107.
- Taylor BA, Hwang KP, Hazle JD, Stafford RJ. Autoregressive moving average modeling for spectral parameter estimation from a multigradient echo chemical shift acquisition. Med Phys 36(3):753-64, 2009. PMID: 19378736.
- Ma J, Slavens Z, Sun W, Bayram E, Estowski L, Hwang KP, Akao J, Vu AT. Linear phase-error correction for improved water and fat separation in dual-echo dixon techniques. Magn Reson Med 60(5):1250-5, 2008. PMID: 18956418.
- Taylor BA, Hwang KP, Elliott AM, Shetty A, Hazle JD, Stafford RJ. Dynamic chemical shift imaging for image-guided thermal therapy: analysis of feasibility and potential. Med Phys 35(2):793-803, 2008. PMID: 18383702.
- Hwang KP, Flask C, Lewin JS, Duerk JL. Selective missing pulse steady state free precession (MP-SSFP): inner volume and chemical shift selective imaging in a steady state sequence. J Magn Reson Imaging 19(1):124-32, 2004. PMID: 14696229.
- Hwang KP, Green JD, Li D, Simonetti OP, Resnick SA, Finn JP, Duerk JL, Omary RA. Minimizing contrast agent dose during intraarterial gadolinium-enhanced MR angiography: In vitro assessment. J Magn Reson Imaging 15(1):55-61, 2002. PMID: 11793457.
- Hwang KP, Lim J, Wendt M, Merkle E, Lewin JS, Duerk JL. Improved device definition in interventional magnetic resonance imaging using a rotated stripes keyhole acquisition. Magn Reson Med 42(3):554-60, 1999. PMID: 10467300.
Invited Articles
- Hwang KP, McKinnon GC, Hoang MV, Slavens ZW, Illerstam F, Peters RD, Shave SL, Maier JK. Achieving Spatial Accuracy in MR for RT Applications. GE Signa Pulse Academic Supplement:9-13, 2014.
- Duerk JL, Butts K, Hwang KP, Lewin JS. Pulse Sequences for Interventional Magnetic Resonance Imaging. Top Magn Reson Imaging 11(3):147-62, 2000. PMID: 11145207.
Abstracts
- Hwang KP, King K, Lai P, Stefan W, McClellan C, Bayram E and Shankaranarayanan A. Application of acceleration methods to Qmap and Synthetic MR imaging. ISMRM Scientific Meeting and Exhibition, 2015.
- Pinnaduwage DS, Chen J, Descovich M, Hwang KP, Pouliot J. Registration accuracy of MR-based images to on-board megavoltage cone-beam CT for brain patient setup. AAPM Annual Meeting, 2014.
- Hwang KP, Illerstam F, Torfeh T, Maier JK, Shave S, Hoang M. Spatial Accuracy QA of an MR System. AAPM Annual Meeting, 2014.
- Hua A, Hwang KP, Pan T. MR-based Cortical Bone Segmentation for PET Attenuation Correction with a Non-UTE 3D fast GRE Sequence. AAPM Annual Meeting, 2014.
- Stefan W, Hwang KP, Hazle JD, Stafford RJ. Improving Vessel Delineation in Brain Using Susceptibility Weighted MRI and Group Sparse Reconstruction. AAPM Annual Meeting, 2014.
- Hwang KP, Son JB, Warntjes M, Bayram E, and Ma J. Fat-water separation in a rapid quantitative mapping sequence. ISMRM Scientific Meeting and Exhibition, 2014.
- Hwang KP, Warntjes M, Stafford RJ, Jackson EF, Madewell JE, Hazle JD, Slavens ZW, Chi TL. Quantitative water content assessment using a single-scan multi-parameter mapping technique and spectral processing of a multiple gradient echo acquisition. ISMRM Scientific Meeting and Exhibition, 2013.
- Hwang KP, Rambow O, Bayram E, Hazle JD, Madewell JE, Slavens ZW, Vu AT, Ma J. Improved single-pass dual echo Dixon imaging with ramp sampling and flexible echo times. ISMRM Scientific Meeting and Exhibition, 2013.
- Wolfgang S, Yeniaras E, Hwang KP, Chi TL, Jackson EF, Hazle JD, Stafford RJ,. Quantitive Proton Resonance Frequency Imaging Using Fast Multi-Echo Gradient-Echo. ISMRM Scientific Meeting and Exhibition, 2013.
- Huang SY, Harmoush S, Abdelsalam ME, Ensor J, Dixon K, Hwang KP, Avritscher R. Evaluation of Liver Fibrosis and Hepatic Venous Pressure Gradient with Magnetic Resonance Elastography in a Novel Swine Model of Cirrhosis. ISMRM Scientific Meeting and Exhibition, 2013.
- Pinnaduwage D, Sudhyadhom D, Descovich M, Hwang K, Novak G, Chen J, Pouliot J. MRI-Based Treatment Planning in Brain Radiation Therapy: Validation of An Atlas-Based Pseudo-CT Generation Method. AAPM Annual Meeting, 2013.
- Hwang KP, Stefan W, Stafford RJ. In Vivo Management of Suspectibility-Induced Distortions of Intracranial MRI Guided Therapies at 3 Telsa. AAPM Annual Meeting, 2013.
- Novak G, Osztroluczki A, Hwang KP, Shave S, Chandler A, Fidrich M. Development of a semi-automated contouring toolkit for pelvic organs on an MR image series. ASTRO Annual Meeting, 2013.
- Hwang KP, McKinnon G, Lorbiecki J, Maier J. Spatial Accuracy Quantification of an MR System. AAPM Annual Meeting, 2012.
- Hwang KP, Maier J, Slavens Z, McKinnon G. Increased MR Spatial Accuracy with Improved Gradient Nonlinearity and Magnet Inhomogeneity Correction. AAPM Annual Meeting, 2012.
- Novak G, Nyiri G, Hwang K, dong L, Fidrich M. Pelvic Bone Segmentation on T1-Weighted MR Images. ASTRO Annual Meeting, 2011.
Patient Reviews
CV information above last modified July 26, 2024