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      Luigi Ricciardiello Image

      Luigi Ricciardiello, MD

      Department of Gastroenterology Hepatology and Nutrition, Division of Internal Medicine

      Present Title & Affiliation

      Primary Appointment

      Professor, Gastroenterology, Hepatology and Nutrition, The University of Texas MD Anderson Cancer Center, Houston, Texas

      Associate Professor on leave without pay since March 1, 2024, Medical and Surgical Sciences, University of Bologna, Bologna

      Dual/Joint/Adjunct Appointment

      Professor, Gastroenterology, Hepatology and Nutrition, The University of Texas MD Anderson Cancer Center, Houston, Texas

      Clinical Interests

      My main clinical interest is on the prevention of digestive cancers, with a particular focus on colorectal cancer. Working side by side with a multidisciplinary group, including genetic counselors, surgeons, oncologists, Ob Gyn specialists, to cite some, I have dedicated the past 15 years on managing patients affected by hereditary gastrointestinal cancer syndromes, and have acquired significant skills in endoscopy for the management of these complex syndromes. Because of this work, the Bologna University Hospital, had become a national center of reference for the management of such patients. I am the senior author of the European Guidelines (ESGE) for the Endoscopic Management of patients with polyposis syndromes, and I have taken part to those dedicated to patients affected by Lynch Syndrome. Furthermore, for 14 years I have also coordinated the colon cancer screening program at the Bologna University Hospital.

      My dedication to this patient's population gave me the opportunity to establish a research program and clinical studies with specific focus on colon cancer prevention. Here is a list of clinical studies:

      1. AIRC (Italian Foundation for Cancer Research)Investigator Grant 2010. 1/1/2011 – 12/31/2013. Project Title: Eicosapentaenoic acid-free fatty acid prevents inflammation and cancer in colitis-associated colorectal cancer. Role: PI
      2. EU-FP7 – Cooperation. 2/1/2013 – 1/31/2018. Project title. PATHWAY-27: “Pivotal Assessment Of The Effects Of Bioactives On Health And Wellbeing. From Human Genoma To Food Industry”. Role: co-PI
      3. AIRC Investigator Grant 2013. 1/1/2014 – 12/31/2016. Project title: Mediterranean diet and Eicosapentaenoic Acid for the prevention of inflammatory and obesity-driven colorectal cancer. Role: PI
      4. Emilia-Romagna Region – Italian Ministry for Health. PI: Giulia Piazzi Project title: Search for novel genes Responsible for familial colorectal polyposis. Role: Participant.
      5. AIRC (Italian Foundation for Cancer Research) Investigator Grant 2018. 1/1/2019 – 02/29/2024. Project Title: Rapamycin, eicosapentaenoic acid and epigallocatechin-3-gallate for the prevention of WNT driven Colorectal Cancer. Role: PI
      6. Helpida Foundation - Molecular characterization of intestinal stem cells, pathways involved in the regulation of stem cell and energy metabolism, and of the intestinal microbiota in patients with colorectal cancer. Role: PI
      7. High levels of EMT-TFs for the diagnosis of Colorectal Cancer (CRC) Role: Participant - Coordinator: Humanitas Research Hospital, Italy
      8. CELTiC - A Multicenter, prospective validation study of the CELTIC panel (biomarkers for the early diagnosis of colorectal cancer). Role: Participant - Coordinator: Amsterdam Medical Center, The Netherlands
      9. Additional diagnostic yield of Artificial Intelligence in the "GENIAL COLONSCOPY”. colonoscopy, for colorectal cancer screening. Role: Participant - Coordinator: Fondazione Poliambulanza Istituto Ospedaliero, Brescia, Italy
      10. Evaluation of Artificial Intelligence System (Gi-Genius) for adenoma detection in Lynch Syndrome. A randomized, parallel, multicenter, controlled trial. TIMELY study. Role: participant - Coordinator: Hospital Clínic - Barcelona, Spain
      11. Evaluation of microbiome and metabolomic profiles in subjects undergoing colorectal cancer screening through fecal immunochemical test (FIT). Role: PI

      I am also the PI of the study EPA-POL-4: A European randomised, double-blind, placebo-controlled, multicenter study to determine the safety and efficacy of EPA-FFA gastro-resistant capsules in Familial Adenomatous Polyposis.


      Education & Training

      Degree-Granting Education

      1994University of Bologna, Bologna, IT, Medicine, Medical Doctor

      Postgraduate Training

      2008-2009Resident, Internal Medicine, Baylor University Medical Center, Dallas, Texas
      2007-2008MD, Internal Medicine, Baylor University Medical Center, Dallas, Texas
      1997-2000Postgraduate Research Gastroenterologist, University of California, San Diego/V.A. San Diego Healthcare System, San Diego, California
      1995-2001Postgraduate Fellow, Gastroenterology, University of Bologna, Bologna

      Licenses & Certifications

      2025TEXAS MEDICAL BOARD
      2001SPECIALIST DIPLOMA IN GASTROENTEROLOGY AND DIGESTIVE ENDOSCOPY, Italy
      1995Provincial Order of Physicians, Surgeons and Dentists of Bologna

      Experience & Service

      Faculty Academic Appointments

      Associate Professor, Medical and surgical sciences, University of Bologna, Bologna, 2014 - 2024

      Senior Research Associate, Gastroenterology, Baylor University Medical Center, Dallas, Texas, 2005 - 2007

      Assistant Professor, Department of Clinical Medicine, University of Bologna, Bologna, 2002 - 2014

      Administrative Appointments/Responsibilities

      Section Director, Research, The University of Texas MD Anderson Cancer Center, Houston, Texas, 2026 - Present

      Section Director, Gastrointestinal hereditary cancers, Gastroenterology and Hepatology, The University of Texas MD Anderson Cancer Center, Houston, Texas, 2025 - Present

      Associate Medical Director, GI Center, The University of Texas MD Anderson Cancer Center, Houston, Texas, 2025 - Present

      Vice Chair Executive Board of the Life-Science Inter-Department Center of the University of Bologna (CIRI Scienze Della Vita), University, University of Bologna, Bologna, 2023 - 2024

      Delegate for Internationalization, Department of Medical and Surgical Sciences, University of Bologna, Bologna, 2023 - 2024

      Coordinator, Area06 (Medicine and Surgery) for the Evaluation Commission of University Research, University of Bologna, University, University of Bologna, Bologna, 2022 - 2024

      Coordinator, Student Exchange Program between University of Bologna and Brown University (Providence, RI, USA) for Medical Sciences, University, University of Bologna, Bologna, 2018 - 2024

      Intramural Institutional Committee Activities

      Member, Executive Board of the Life-Science Inter-Department Center (CIRI scienze della vita), University of Bologna, 2021 - 2024

      Member, GTA-Health group (coordinating activities for European Grants), University of Bologna, 2017 - 2024

      Member, Organizing committee of the English School of Medicine, University of Bologna, 2016 - 2017

      Extramural Institutional Committee Activities

      Member, Italian Association of Medical Oncology - Colonic Tumors, Italian Association of Medical Oncology, 2020 - 2021

      Member, European Society of Gastrointestinal Endoscopy: Post-polypectomy colonoscopy surveillance guideline, European Society of Gastrointestinal Endoscopy, 2019 - 2019

      Member, European Society of Gastrointestinal Endoscopy: Endoscopic management of Lynch syndrome and of familial risk of colorectal cancer guidelines, European Society of Gastrointestinal Endoscopy, 2018 - 2019

      Member, European Society of Gastrointestinal Endoscopy: Endoscopic management of polyposis syndromes guidelines, European Society of Gastrointestinal Endoscopy, 2018 - 2019

      Editorial Activities

      Editor - Hereditary Disorders issue, Bailliere's best practice & research. Clinical gastroenterology, 2021 - 2022

      Managing Editor, Digestive Diseases, 2016 - Present

      Honors & Awards

      2021Bengt Ihre Medal, Svenska Gastrodagarna
      2019Accademico Corrispondente Residente, Accademia delle Scienze dell’Istituto di Bologna
      2013UEG Week 2013. Poster of Excellence, United European Gastroenterology
      2013Digestive Disease Week. POSTER OF DISTINCTION, American Gastroenterological Association
      2009United European Gastroenterology week and World Congress of Gastroenterology 2009. Best Abstract Award, United European Gastroenterology and World Gastroenterology Organization
      2009Digestive Disease Week 2009, POSTER OF DISTINCTION, American Gastroenterological Association
      2005Astra Zeneca Emerging Leaders in Gastroenterology, Astra Zeneca
      2005Digestive Disease Week 2005 Poster of Distinction, American Gastroenterological Association
      200412th United European Gastroenterology Week BEST ABSTRACT AWARD, United European Gastroenterology
      200311th United European Gastroenterology Week BEST ABSTRACT AWARD, United European Gastroenterology
      2003United European Gastroenterology Week 2003 Travel Grant Award, United European Gastroenterology
      2003Digestive Disease Week 2003 Poster of Distinction, American Gastroenterological Association
      2003IX Congresso Nazionale delle Malattie Digestive. BEST ORAL PRESENTATION, Italian Federation of Digestive Diseases
      200210th United European Gastroenterology Week (2002) Best 200 abstracts award, United European Gastroenterology
      200210th United European Gastroenterology Week (2002)Travel Grant, United European Gastroenterology Week
      2002Digestive Disease Week 2002 Poster of Distinction, American Gastroenterological Association
      2000Digestive Disease Week 2000 Poster of Distinction, American Gastroenterological Association

      Professional Memberships

      International Society for Gastrointestinal Hereditary Tumours

      2026 - Present

      Collaborative group of

      2024 - Present

      United European Gastroenterology

      2023 - Present

      Biomed Alliance

      2020 - 2022

      Federation of the Italian Societies for Digestive Diseases

      2020 - 2023

      United European Gastroenterology

      2019 - 2022

      Italian Society of Gastroenterology

      2019 - 2023

      European Society of Gastrointestinal Endoscopy

      2018 - Present

      European Hereditary Tumour Group

      2018 - Present

      Italian Society of Digestive Endoscopy

      2018 - Present

      UNIGASTRO

      2018 - 2023

      United European Gastroenterology

      2017 - 2022

      United European Gastroenterology

      2017 - 2018

      United European Gastroenterology

      2014 - 2016

      European Society for Digestive Oncology

      2013 - Present

      United European Gastroenterology

      2013 - 2016

      Italian Society of Gastroenterology

      2013 - 2016

      International Society for Gastrointestinal Hereditary Tumours Incorporated

      2011 - Present

      American College of Physicians

      2008 - 2015

      Italian Society of Gastroenterology

      2004 - 2008

      American gastroenterological Association

      1998 - Present

      Order of Physicians

      1995 - Present

      Selected Presentations & Talks

      Local Presentations

      1. 2026. Unexplained Polyposis and APC Somatic Mosaicism. Invited. 9TH ANNUAL HEREDITARY CANCER SYMPOSIUM for Health Care Providers. Houston, Texas, US.
      2. 2025. ETIOLOGIES OF POLYPOSIS: MOSAICISM, METHYLATION, & MICROBIOME. Invited. Onco-GI Lecture. Houston, Texas, US.
      3. 2024. Hereditary GI cancer syndromes: need for personalized prevention strategies. Invited. Division of Internal Medicine Grand Rounds. Houston, Texas, US.
      4. 2022. Quali novita' in Endoscopia?. Invited. Come sta lo screening del colon retto in Emilia Romagna?. Bologna, IT.
      5. 2021. Hereditary Colorectal Cancer Syndromes for Surgeons. Invited. Surgical Grand Round. Ravenna, IT.
      6. 2020. The impact of germline mutations on gastrointestinal cancers: from MSI to NGS. Results, issues and perspectives. Invited. Grand Rounds, Cancer Center Humanitas Research Hospital. Rozzano, IT.
      7. 2015. Screening del Cancro Colorettale: linee guida e possibili sviluppi. Invited. Fondazione ANT, Seminari di Oncologia 2015. Bologna, IT.
      8. 2010. Dieta e cancro colo rettale: le basi molecolari della prevenzione. Invited. Nutrizione, attività fisica e cancro. Bologna, IT.

      Regional Presentations

      1. 2026. GI Genetics: Vaccine trials/registry. Invited. Summer Sawyer GI Conference 2026. San Antonio, Texas, US.
      2. 2023. Approcci innovativi nello screening del cancro colo-rettale. Invited. CONGRESSO AIGO-SIED-SIGE EMILIA ROMAGNA. LA GASTROENTEROLOGIA DEL FUTURO: INNOVAZIONI DIAGNOSTICO-TERAPEUTICHE E RISPETTO PER L’AMBIENTE. Reggio Emilia, IT.
      3. 2023. Applicazione dell’intelligenza artificiale nel management delle sindromi ereditarie ad alto rischio oncologico. Invited. ENDOBOAT. Forli, IT.
      4. 2021. Lo screening in epoca Covid 19. Invited. CANCRO COLO-RETTALE, SCREENING E COLONSCOPIA DI QUALITÁ: CRITICITÁ NEL SUD ITALIA. Bari, IT.
      5. 2016. La Prevenzione del cancro colo-rettale: dal laboratorio alla pratica clinica. Invited. VIAGGIO AL CENTRO DELL’UOMO. Itinerari Endoscopici. Pesaro, IT.
      6. 2015. Gli ingredienti della salute. Invited. Il futuro della prevenzione comincia in classe. Milan, IT.

      National Presentations

      1. 2026. Idiopathic Adenomatous Polyposis: Is There a Role For Chemoprevention?. Invited. Cutting-Edge Advances in Idiopathic Adenomatous Polyposis (IAP). Fiesole, Tuscany, IT.
      2. 2026. Adenoma Incidence Trends by Genotype in Lynch Syndrome: A Retrospective Cohort Study of 318 MD Anderson Cancer Center Patients. Conference. InSIGHT 2026. Singapore, SG.
      3. 2025. Hereditary Live. Panelist. CGA-IGC 2025. St. Louis, Missouri, US.
      4. 2025. Adenoma Incidence trends by genotype in Lynch Syndrome: a retrospective cohort study of 318 MD Anderson Cancer Center Patients. Poster. CGA-IGC 2025. St. Louis, Missouri, US.
      5. 2025. TRENDS IN ADENOMA INCIDENCE AMONG PMS2 MUTATION CARRIERS: CLINICALIMPLICATIONS FOR LYNCH SYNDROME SURVEILLANCE. Poster. Digestive Disease Week 2025. San Diego, California, US.
      6. 2025. ETIOLOGIES OF POLYPOSIS: MOSAICISM, METHYLATION, & MICROBIOME. Invited. Digestive Disease Week 2025. San Diego, California, US.
      7. 2023. L’importante ruolo del microbiota intestinale nell’immunoterapia oncologica. Invited. Il mondo del microbiota. Rome, IT.
      8. 2023. Colorectal cancer prevention with dietary omega 3 polyunsaturated fatty acids either alone or in combination with other molecules, through targeting key molecular pathways and the gut microbiota. Invited. AIRC - CONVEGNO NAZIONALE DI ONCOLOGIA. Bologna, IT.
      9. 2023. Colorectal cancer and gut microbiota Luigi Ricciardiello. Invited. Microbiota Revolution. Bologna, IT.
      10. 2023. Cosa c’è di nuovo nel 2022: impatto delle recenti evidenze sulla prevenzione, diagnosi e management dei tumori colorettali. Invited. Gastroenterologia ed Endoscopia Digestiva in Italia oggi - State of the Art. Firenze, IT.
      11. 2023. Burden of Digestive Disease: Is it ripe time for Italian White Book Update?. Invited. Clinical Cases in Gastroenterology and Hepatology. Montecatini Terme, IT.
      12. 2023. La ricerca. Invited. CONVEGNO NAZIONALE GISCoR 2023 on colorectal cancer screening. Palermo, IT.
      13. 2023. Programmi organizzati di screening: possiamo fare meglio?. Invited. 29 Congresso Nazionale delle Malattie Digestive. Rome, IT.
      14. 2023. The burden and economic impact of digestive diseases in the European Region, and investigation of research gaps and priorities in the field of digestive health: results of the UEG White Book 2.0. Invited. 29 Congresso Nazionale delle Malattie Digestive. Rome, IT.
      15. 2022. Sorveglianza post polipectomia. Invited. Corso Nazionale SIED 2022. Rome, IT.
      16. 2022. Lo screening basato sul rischio - Le raccomandazioni delle societa' scientifiche. Invited. GISCoR - Gruppo italiano Screening Colorettale - XV Congresso Nazionale. Reggio Emilia, IT.
      17. 2022. UEG e la ricerca sulle malattie dell'Apparato Digerente. Invited. 28 Congresso Nazionale delle Malattie Digestive. Rome, IT.
      18. 2021. Colorectal cancer e microbiota intestinale. Invited. Top Ten in Gastroenterologia. Bergamo, IT.
      19. 2021. Caratterizzazione molecolare del tumore del colon retto. Invited. 27 Congresso Nazionale delle Malattie Digestive. Virtual, IT.
      20. 2021. UEG e la ricerca sulle malattie dell'apparato Digerente. Invited. 27 Congresso Nazionale delle Malattie Digestive. Virtual, IT.
      21. 2020. Lo Screening Come Piattaforma di Ricerca. Invited. 26 Congresso Nazionale delle Malattie Digestive. Virtual, IT.
      22. 2019. Il futuro della ricerca scientifica sulle Malattie dell’Apparato Digerente in Europa: il ruolo di UEG. Invited. 25 Congresso Nazionale delle Malattie Digestive. Rome, IT.
      23. 2018. United European Gastroenterology: le sfide future della gastroenterologia Europea. Invited. 24 Congresso Nazionale delle Malattie Digestive. Rome, IT.
      24. 2017. United European Gastroenterology: grandi opportunità per i gastroenterologi europei. Invited. 23° Congresso Nazionale delle Malattie Digestive. Bologna, IT.
      25. 2017. Tavola Rotonda: Focus sui tumori ereditari dello stomaco, del colon e del pancreas. Lecture: "Colon". Invited. 23° Congresso Nazionale delle Malattie Digestive. Bologna, IT.
      26. 2017. Innovations in Gastroenterology, foreign experiences imported in Italy. Invited. XII International Congress in Gastroenterology and Hepatology. Challenges and opportunities: new paradigms in acid related diseases. Florence, IT.
      27. 2017. Obesità e cancro gastrointestinale. Invited. Grandangolo in Gastroenterologia ed Epatologia 2017. Milan, IT.
      28. 2015. "Microbiota e carcinogenesi" during the session "Dieta e tumori dell’apparato digerente". Invited. XXXVI congresso Società Italiana di Nutrizione Umana. Firenze, IT.
      29. 2015. La storia familiare nelle neoplasie colorettali: un enigma genetico? Lecture on: Criticità di percorso. Invited. Corso nazionale AIGO 2015. Treviso, IT.
      30. 2015. CARCINOMA DEL COLON TRA PREVENZIONE, GENETICA, SCREENING E CHIRURGIA PERSONALIZZATA. Invited. 117° CONGRESSO NAZIONALE della Società Italiana di Chirurgia. Milan, IT.
      31. 2015. Dal polipo al cancro: storia naturale della carcinogenesi del colon. Invited. Corso Nazionale SIGE "Il Saper Fare". Castel San Pietro, IT.
      32. 2013. New foods for CRC prevention. Invited. 7th Probiotics, Prebiotics & New Foods. Rome, IT.
      33. 2013. Chemoprevention of colorectal cancer by the omega-3-PUFA eicosapentaenoic acid. Invited. International Symposium on "Natural Products in Cancer Prevention and Therapy". Napoli, IT.
      34. 2012. Chemioprevenzione delle sindromi ereditarie di cancro colorettale. Invited. 4th Workshop ON Gastrointestinal Oncology, 2012. Rome, IT.
      35. 2012. Genetica del carcinoma colorettale: implicazioni per la diagnosi, la terapia e la sorveglianza. Invited. Corso nazionale SIED. Modena, IT.
      36. 2012. Colon cancer prevention and dietary bioactives. Invited. Diet, Microbiota and Gut Health. International Workshop among scientists from Institute of Food Research, University of Bologna and New Zealand universities. Bologna, IT.
      37. 2010. IBD and cancer: whom to survey, how to prevent it. Invited. Inflammatory bowel diseases: agreement and controversies. San Donato Milanese, IT.
      38. 2007. Stem cell and its implication for GI disease. Invited. The patient: a comprehensive approach. Florence, IT.
      39. 2004. Mutational complexity in colorectal cancer". dal 30-11-2004 al 30-11-2004. Invited. Evolving Concepts in the management of benign and malignant digestive diseases, Firenze, 2004. Florence, IT.
      40. 2004. Screening Projects for Colorectal Cancer. Invited. lnternational Workshop on Diagnostic and Operative Digestive Endoscopy, Taormina, 2004. Taormina, IT.
      41. 2004. I tests genetici per il cancro del colondal. Invited. X Congresso Nazionale delle Malattie Digestive. Turin, IT.
      42. 2003. The tests of the future. Invited. Colo-rectal cancer screening. Frascati (Rome), IT.
      43. 2003. The nature and the clinical features of increased familial susceptibility for colorectal cancer. Invited. 3rd update on Helicobacter pylori research and other Emerging issued on digestive cancer prevention. Bologna, IT.
      44. 2003. Il paziente operato di CCR. Invited. Secondo Campus Associazione Giovani Gastroenterologi Italiani (AGGEI), 2002. Imola, IT.
      45. 2003. In Vivo activation of the p53-MDM2 system in microsatellite unstable-hMLH1 defective colorectal cancers. Conference. IX Congresso Nazionale delle Malattie Digestive. Florence, IT.
      46. 2002. I COX2 in Gastroenterologia. Invited. VIII Congresso Nazionale delle Malattie Digestive. Rome, IT.
      47. 2002. Infezioni e cancro del colon. Invited. Congresso CIRANAD. Napoli, IT.
      48. 2001. La gestione del paziente con pancreatite acuta. Invited. Associazione Giovani Gastroenterologi Italiani (AGGEI). Bologna, IT.

      International Presentations

      1. 2024. La gestione delle sindromi ereditarie del colon. Invited. CORSO DI FORMAZIONE REGIONALE FISMAD “COLON 2024”, US.
      2. 2023. Current trends in GI oncology. UEG White Book. Invited. XI LATVIJAS GASTROENTEROLOĢIJAS KONGRESS. Riga, LV.
      3. 2022. Screening intervals for Lynch syndrome: More frequent colonoscopic surveillance does not decrease CRC in Lynch syndrome patients. Invited. 9th Biennial Meeting of the International Society for Gastrointestinal Hereditary Tumours (InSiGHT) 2022. New Jersey City, US.
      4. 2022. Prevenzione del cancro del colon - Early Onset. Invited. 28 Congresso Nazionale delle Malattie Digestive. Rome, IT.
      5. 2021. Impact of COVID-19 on CRC Screening. Invited. UEG Week 2021 Virtual. Vienna, AT.
      6. 2021. Honorary Lecture Bengt Ihre: UNDERSTANDING HEREDITARY GI CANCER SYNDROMES – FROM FAMILY HISTORY TO PERSONALIZED MANAGEMENT. Invited. Svenska Gastrodagarna 2021. Malmo, SE.
      7. 2019. Current Trends in Digestive Oncology. Invited. State of the art lecture: Current Trends in Digestive Oncology. Riga, LV.
      8. 2019. Chemopreventive strategies for patients at high risk for colorectal cancer. Invited. 19th Congress of Gastroenterology China, CGC 2019. Guiyang, CN.
      9. 2018. United European Gastroenterology: new opportunities for young Gastroenterologists across Europe. Invited. 1st European Congress of Young Gastroenterologists. Zagreb, HR.
      10. 2018. Chemoprevention in GI Cancers Focus on High-risk Colorectal Cancers. Invited. Annual congress of the Czech Society of Gastroenterology. Karlovy Vary, CZ.
      11. 2018. Chemoprevention in Colorectal Cancer – Possible New Strategies. Invited. 35th Turkish National Gastroenterology Week. Antalya, TR.
      12. 2018. APC Somatic Mosaicism. Invited. CGA Annual Meeting. San Diego, US.
      13. 2018. BEST OF UEG WEEK BARCELONA 2017. Invited. 18th Congress of Gastroenterology China, CGC 2018. Dalian, CN.
      14. 2018. Chemoprevention of hereditary GI cancers: state of the art. Invited. European Hereditary Tumour Group 2018. Nice, FR.
      15. 2017. Update on Oncology. Invited. VIII Latvian Gastroenterology Congress. Riga, LV.
      16. 2017. Challenges in diagnosing and managing Hereditary Colorectal Cancer Syndromes. Invited. 37th Panhellenic Congress of Gastroenterology. Thessaloniki, GR.
      17. 2017. What can UEG do for gastroenterologists in Ukraine? What can Ukranian gastroenterologists do for UEG?. Invited. Ukranian Society of Gastroenterology Meeting. Kiev, UA.
      18. 2017. Updates on UEG activities. Invited. Annual meeting of the Croatian Society of Gastroenterology. Korcula, HR.
      19. 2017. Colorectal cancer chemoprevention. Invited. Semana Digestiva 2017. Albufeira, PT.
      20. 2017. United European Gastroenterology (UEG) - great opportunities for gastroenterologists across the globe. Invited. Innovations in Gastroenterology, Tel Aviv, 2017. Tel Aviv, IL.
      21. 2016. Rising Stars in irritable bowel syndrom (IBS) from Europe and the USA: Words of welcome0-2016 al 17-10-2016. Invited. United European Gastroenterology Week 2016. Vienna, AT.
      22. 2016. "Prevention of GI cancers: Nutrition and chemoprevention: What is the evidence from lab studies?". Invited. United European Gastroenterology Week 2016. Vienna, AT.
      23. 2016. United European Gastroenterology (UEG) - great opportunities for gastroenterologists across the globe. Invited. Russian Gastroenterology Week 2016. Moscow, RU.
      24. 2016. BEST UEG WEEK BARCELONA 2015. Invited. CGC2016, The 16th Congress of Gastroenterology China. Suzhou, CN.
      25. 2016. United European Gastroenterology: Great Opportunities for European Gastroenterologists. Invited. UEG Course - Update in chronic digestive diseases: What is changing, what is challenging?. Cluji-Napoca, RO.
      26. 2015. Molecular Mechanisms in Colorectal Cancerogenesis. Invited. Fit for the Future in Gastroenterology Meeting 2015. Berlin, DE.
      27. 2015. Lecture during the session entitled "Obesity and cancer: is there a link?" Title of the talk: What are the molecular pathways?. Invited. United European Gastroenterology Week 2015. Barcelona, ES.
      28. 2015. State of the art lecture during the session entitled "Novel Approaches to colorectal cancer". Invited. United European Gastroenterology Week 2015. Barcelona, ES.
      29. 2015. Does faecal DNA testing play a role in colorectal cancer?. Invited. United European Gastroenterology Week 2015. Barcelona, ES.
      30. 2014. Obesity - The New Killer Disease - TheRole of Primary Healthcare. Invited. Improving outcomes in Cancer. Ministry of Health, Social Services and Equality Madrid. Madrid, ES.
      31. 2013. Fecal microbiome transplantation. Invited. European Bridging Meeting in Gastroenterology 2013. Berlin, DE.
      32. 2013. Chemoprevention of colorectal cancer with bioactives from the Mediterranean Diet. Invited. Piscataway, US.
      33. 2013. Colorectal cancer screening 13 years after the start: how to keep it going?. Invited. II European Colorectal Cancer Days 2013, Brno, Czech Republic. Brno, CZ.
      34. 2012. State of the Art Lecture during the session "Insights into colorectal cancer pathogenesis". Invited. United European Gastroenterology Week 2012. Amsterdam, NL.
      35. 2012. Young and considering to apply for EU funding? Yes it’s possible!. Invited. United European Gastroenterology Week 2012. Amsterdam, NL.
      36. 2012. Developments in chemoprevention strategies durante la sessione. Invited. United European Gastroenterology Week 2012. Amsterdam, NL.
      37. 2012. Case study: participation in the EU funding scheme. Invited. Research Symposium on digestive and liver diseases, European Parliament. Bruxelles, BE.
      38. 2012. Colorectal Cancer and Obesity - An International Perspective of Cancer Epidemiology. Invited. Digestive Disease Week 2012. San Diego, US.
      39. 2011. Repression of Polyp Formation and Growth by Highly Pure Eicosapentaenoic Acid in APCMIN/+Mice. Conference. The International Society for Gastrointestinal Hereditary Tumours (InSiGHT) 2011 Biannual Meeting. San Antonio, US.
      40. 2005. Lack Of E-Cadherin and Membrane Beta Catenin Expressions in Sporadic Colon Cancer With Hmlh1 Promoter Hypermethylation and Microsatellite Instability. Conference. Digestive Disease Week 2005, Chicago, Illinois, USA. Chicago, US.
      41. 2004. Microsatellite-unstable, hMLH1-hypermethylated, colorectal cancers display high expression of thymidylate synthase and functional p53 system: implications for chemotherapeutic strategies and clinical outcome. Conference. Prague, CZ.
      42. 2004. Cancer surveillance in IBD. Will non-invasive tests replace colonoscopy?. Invited. United European Gastroenterology Week, 2004. Prague, CZ.
      43. 2002. Loss Of hMLH1 By Promoter Hypermethylation Leads To Microsatellite Instability In Adenomatous Polyps Of Patients With A Single First-Degree Member Affected By Colon Cancer. Conference. United European Gastroenterology Week 2002. Geneva, CH.
      44. 2000. Rearrangements of JC virus Mad-1 promoter region are frequent events in infected colon cancers but not in matched normal tissues. Conference. Digestive Disease Week 2000. San Diego, US.
      45. 1999. Integration of the Human Polyomavirus JCV DNA sequences in human colon cancer DNA. Conference. Digestive Disease Week 1999. Orlando, US.

      Formal Peers

      1. 2018. Multidisciplinary management of colon and rectal cancer. Bologna, IT.
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      Grant & Contract Support

      Title:Great Lakes New England Clinical Validation Center
      Funding Source:NCI
      Role:PI
      ID:U01CA086400

      Selected Publications

      Peer-Reviewed Articles

      1. Deng, N, Duzagac, F, Bolivar, AM, Reyes-Uribe, L, Taggart, MW, Thirumurthi, S, Ricciardiello, L, Lynch, PM, You, YN, Kopetz, S, Scheet, PA, Lizee, GA, Reuben, A, Marin, F, Pineda, M, Sinha, K, Bansal, A, Capellá, G, Vilar Sanchez, E. Genomic analysis of T Cell receptors reveals lynch syndrome specific immune signatures. Nature communications 17(1), 2026. e-Pub 2026. PMID: 41932865.
      2. Calafato G, Bernardi A, Alquati C, Cuicchi D, Buttitta F, Di Paola FJ, Pierantoni C, Ceccarelli C, Pariali M, Piazzi G, Ricciardiello L. Omega-3 polyunsaturated fatty acids and epigallocatechin-3-gallate attenuate obesity-associated CD44-high stemness in colorectal cancer through modulation of Notch1, Wnt/beta-catenin and PI3K/mTOR signaling. Biomed Pharmacother 203:119900, 2026. e-Pub 2026. PMID: 42685494.
      3. Punzo A, Silla A, Porru E, Comito R, Gozzi G, Bevilaqua V, Ricciardiello L, Viviani V, Cerra B, Gioiello A, Roda A, Caliceti C. Lighting Up Gut Dysbiosis: Red-Shifted Whole-Cell Bioluminescence Enables Functional Sensing of Bile Salt Hydrolase Activity in Human Feces. ACS Sens, 2026. e-Pub 2026. PMID: 42687409.
      4. Patel SG, Loomans-Kropp HA, Foda ZH, Katona BW, Birz S, Burke CA, Clawson J, Furner B, Hochheimer C, Magnan E, Ricciardiello L, Singh H, Volchenboum S, Watkins M, Yen T, Abbass M, Bartell NJ, Dudley B, Engelking L, Guillem J, Hollis R, Idos G, Jones BA, Kanth P, Kastrinos F, Li D, Lucas AL, Mankaney GN, Maratt JK, Marino D, Melson J, Nguyen LH, Reddy KM, Schrader KA, Silva-Smith R, Singh A, Stanich PP, Stoffel EM, Syngal S, Weiss JM, Yurgelun MB, Zakalik D, Gupta S, Bansal A, Kupfer SS. Lynch syndrome integrative epidemiology and genetics (LINEAGE): rationale for cohort design. Fam Cancer 25(2), 2026. e-Pub 2026. PMID: 42089916.
      5. Spada C, Cesaro P, Fuccio L, Salvi D, Ferrari C, Barbaro F, Bizzotto A, Butitta F, Gerardi V, Lovera M, Milluzzo SM, Minelli Grazioli L, Olivari N, Pecere S, Piccirelli S, Pugliano CL, Pesatori EV, Quadarella A, Tettoni E, Zani C, Ricciardiello L, Costamagna G. Impact of Artificial Intelligence for Detection of Precancerous Colonic Lesions in a Fecal Immunochemical Blood Test-Based Organized Screening Program in Italy: A Randomized Control Trial. United European Gastroenterol J 14(1):e70176, 2026. e-Pub 2026. PMID: 41563802.
      6. Deng N, Duzagac F, Bolivar AM, Reyes-Uribe L, Taggart MW, Thirumurthi S, Ricciardiello L, Lynch PM, You Y, Kopetz S, Scheet P, Lizee GA, Reuben A, Marin F, Pineda M, Sinha KM, Bansal A, Capella G, Vilar E. International Guidelines On Clinical Management, Surveillance, And Prevention. Nat Cancer. e-Pub 2026.
      7. Ricciardiello L, You YN. Enhancing Standardization in the Pediatric Management of Hereditary Polyposis Syndromes. Cancer Prev Res (Phila) 18(10):579-581, 2025. e-Pub 2025. PMID: 40843510.
      8. Bouchiba, H, Aelvoet, AS, Pellise, M, Bastiaansen, BA, Van Leerdam, M, Langers, AM, Balaguer, F, Miedema, TN, Anele, CC, Daca-Alvarez, M, Bossuyt, PM, Ricciardiello, L, Jover, R, Hompes, R, Karstensen, JG, Latchford, A, Dekker, E. Risk of Cancer and Reoperation After Ileorectal Anastomosis and Ileal Pouch-Anal Anastomosis in Familial Adenomatous Polyposis. American Journal of Gastroenterology 120(9):2132-2138, 2025. e-Pub 2025. PMID: 39787348.
      9. Punzo A, Silla A, Pannuti A, Gozzi G, Buttitta F, Tardio ML, D'Errico A, Cuicchi D, Zambito G, Mezzanotte L, Dikici E, Boschetti E, Ratti S, Deo SK, Ricciardiello L, Roda A, Daunert S, Caliceti C. Jagged1-Fluc: A Luminescent Recombinant Protein as a Sensitive Tool for High-Throughput Screening of Colorectal Cancer. Biofactors 51(5):e70049, 2025. e-Pub 2025. PMID: 41078290.
      10. Minato, I, Mena, P, Ricciardiello, L, Scaioli, E, Belluzzi, A, Rotondo, E, Derlindati, E, Montanini, B, Michelini, C, Tosi, N, Agullò Garcià, V, Picone, G, Mengucci, C, Dobani, S, Salamanca, P, Rosi, A, Dall'Asta, M, Bresciani, L, Curti, C, Spisni, E, Cas, AD, Bordoni, A, Tomás-Barberán, FA, Ferguson, LR, Del Rio, D, Danesi, F. Evidence for a Modulatory Effect of a 12-Week Pomegranate Juice Intervention on the Transcriptional Response in Inflammatory Bowel Disease Patients Reducing Fecal Calprotectin Levels. Molecular Nutrition and Food Research 69(15), 2025. e-Pub 2025. PMID: 40255128.
      11. Kortlever, T, Ferlizza, E, Lauriola, M, Borrelli, F, Porro, A, Spaander, MC, Bossuyt, PM, Ricciardiello, L, Dekker, E. Diagnostic Accuracy of an Add-On, Blood-Based Screening Test for Colorectal Cancer in Two Established Screening Programmes. Alimentary Pharmacology and Therapeutics 61(12):1935-1943, 2025. e-Pub 2025. PMID: 40207404.
      12. Pezzoli A, Buttitta F, Palmonari C, Simoni M, Pierantoni C, Merighi A, Ricciardiello L. Prevalence and Endoscopic Features of Colorectal Non-Polypoid Lesions: A Single-Center Retrospective Study from a Large Cohort of Fecal Immunochemical Test-Positive Screening Patients in Northern Italy. Dig Dis 43(2):235-245, 2025. e-Pub 2025. PMID: 39837308.
      13. Calafato, G, Alquati, C, Bernardi, A, Di Paola, FJ, Ricciardiello, L. Comparative Analysis of Commercial and Home-Made Media on RSPO1/S6R Axis in Organoids with Different Wnt Backgrounds. International journal of molecular sciences 25(21), 2024. e-Pub 2024. PMID: 39519079.
      14. Maida, M, Ramai, D, Mori, Y, Dinis-Ribeiro, M, Facciorusso, A, Hassan, C, Arvanitakis, M, Barakat, MT, Bisschops, R, Byrne, KR, Dekker, E, Fang, J, Fuccio, L, Gkolfakis, P, Leighton, JA, Lorenzo-Zúñiga, V, Hass, DJ, Maida, CD, Ofosu, A, Oxentenko, AS, Radaelli, F, Ricciardiello, L, Rutter, M, Stout, J, Triantafyllou, K. The role of generative language systems in increasing patient awareness of colon cancer screening. Endoscopy 57(3):262-268, 2024. e-Pub 2024. PMID: 39142348.
      15. Ortiz O, Daca-Alvarez M, Rivero-Sanchez L, Gimeno-Garcia AZ, Carrillo-Palau M, Alvarez V, Ledo-Rodriguez A, Ricciardiello L, Pierantoni C, Huneburg R, Nattermann J, Bisschops R, Tejpar S, Huerta A, Riu Pons F, Alvarez-Urturi C, Lopez-Vicente J, Repici A, Hassan C, Cid L, Cavestro GM, Romero-Mascarell C, Gordillo J, Puig I, Herraiz M, Betes M, Herrero J, Jover R, Balaguer F, Pellise M. An artificial intelligence-assisted system versus white light endoscopy alone for adenoma detection in individuals with Lynch syndrome (TIMELY): an international, multicentre, randomised controlled trial. Lancet Gastroenterol Hepatol 9(9):802-810, 2024. e-Pub 2024. PMID: 39033774.
      16. Imada S, Khawaled S, Shin H, Meckelmann SW, Whittaker CA, Correa RO, Alquati C, Lu Y, Tie G, Pradhan D, Calibasi-Kocal G, Nascentes Melo LM, Allies G, Rosler J, Wittenhofer P, Krystkiewicz J, Schmitz OJ, Roper J, Vinolo MAR, Ricciardiello L, Lien EC, Vander Heiden MG, Shivdasani RA, Cheng CW, Tasdogan A, Yilmaz OH. Short-term post-fast refeeding enhances intestinal stemness via polyamines. Nature 633(8031):895-904, 2024. e-Pub 2024. PMID: 39169180.
      17. Di Paola FJ, Alquati C, Conti G, Calafato G, Turroni S, D'Amico F, Ceccarelli C, Buttitta F, Bernardi A, Cuicchi D, Poggioli G, Turchetti D, Ferrari S, Cannizzaro R, Realdon S, Brigidi P, Ricciardiello L. Interplay between WNT/PI3K-mTOR axis and the microbiota in APC-driven colorectal carcinogenesis: data from a pilot study and possible implications for CRC prevention. J Transl Med 22(1):631, 2024. e-Pub 2024. PMID: 38970018.
      18. Aelvoet AS, Pellise M, Miedema TN, Daca-Alvarez M, Bastiaansen BAJ, van Leerdam ME, Jover R, Balaguer F, Kaminski MF, Buttitta F, Ricciardiello L, Jespersen N, Karstensen JG, Bossuyt PMM, Latchford A, Hompes R, Dekker E. Development of Desmoid Tumors After Ileorectal Anastomosis Versus Ileal Pouch-Anal Anastomosis in Familial Adenomatous Polyposis. Clin Gastroenterol Hepatol 22(11):2319-2326, 2024. e-Pub 2024. PMID: 38969075.
      19. Aelvoet AS, Karstensen JG, Bastiaansen BAJ, van Leerdam ME, Balaguer F, Kaminski M, Hompes R, Bossuyt PMM, Ricciardiello L, Latchford A, Jover R, Daca-Alvarez M, Pellise M, Dekker E. Cold snare polypectomy for duodenal adenomas in familial adenomatous polyposis: a prospective international cohort study. Endosc Int Open 11(11):E1056-E1062, 2023. e-Pub 2023. PMID: 37954110.
      20. Aelvoet AS, Pellise M, Bastiaansen BAJ, van Leerdam ME, Jover R, Balaguer F, Kaminski MF, Karstensen JG, Saurin JC, Hompes R, Bossuyt PMM, Ricciardiello L, Latchford A, Dekker E. Personalized endoscopic surveillance and intervention protocols for patients with familial adenomatous polyposis: the European FAP Consortium strategy. Endosc Int Open 11(4):E386-E393, 2023. e-Pub 2023. PMID: 37102182.
      21. Cavestro GM, Mannucci A, Balaguer F, Hampel H, Kupfer SS, Repici A, Sartore-Bianchi A, Seppala TT, Valentini V, Boland CR, Brand RE, Buffart TE, Burke CA, Caccialanza R, Cannizzaro R, Cascinu S, Cercek A, Crosbie EJ, Danese S, Dekker E, Daca-Alvarez M, Deni F, Dominguez-Valentin M, Eng C, Goel A, Guillem JG, Houwen BBSL, Kahi C, Kalady MF, Kastrinos F, Kuhn F, Laghi L, Latchford A, Liska D, Lynch P, Malesci A, Mauri G, Meldolesi E, Moller P, Monahan KJ, Moslein G, Murphy CC, Nass K, Ng K, Oliani C, Papaleo E, Patel SG, Puzzono M, Remo A, Ricciardiello L, Ripamonti CI, Siena S, Singh SK, Stadler ZK, Stanich PP, Syngal S, Turi S, Urso ED, Valle L, Vanni VS, Vilar E, Vitellaro M, You YN, Yurgelun MB, Zuppardo RA, Stoffel EM. Delphi Initiative for Early-Onset Colorectal Cancer (DIRECt) International Management Guidelines. Clin Gastroenterol Hepatol 21(3):581-603.e33, 2023. e-Pub 2023. PMID: 36549470.
      22. Russo M, Barchi A, Mannucci A, Puzzono M, Zuppardo RA, Biamonte P, Bencardino S, Leandro G, Cannizzaro R, Monica F, Zagari RM, Pasquale L, Goni E, Di Leo M, Ricciardiello L, Cavestro GM. Increased Number of Colorectal Interval Cancers in Lynch Syndrome after the SARS-CoV-2 Pandemic: A Survey-Based Study. Dig Dis 41(2):227-232, 2023. e-Pub 2023. PMID: 35468603.
      23. Ianiro G, Ollivier M, Ricciardiello L. Reducing bureaucracy in clinical trials. United European Gastroenterol J 10(9):1029-1030, 2022. e-Pub 2022. PMID: 36225092.
      24. Moller P, Seppala T, Dowty JG, Haupt S, Dominguez-Valentin M, Sunde L, Bernstein I, Engel C, Aretz S, Nielsen M, Capella G, Evans DG, Burn J, Holinski-Feder E, Bertario L, Bonanni B, Lindblom A, Levi Z, Macrae F, Winship I, Plazzer JP, Sijmons R, Laghi L, Valle AD, Heinimann K, Half E, Lopez-Koestner F, Alvarez-Valenzuela K, Scott RJ, Katz L, Laish I, Vainer E, Vaccaro CA, Carraro DM, Gluck N, Abu-Freha N, Stakelum A, Kennelly R, Winter D, Rossi BM, Greenblatt M, Bohorquez M, Sheth H, Tibiletti MG, Lino-Silva LS, Horisberger K, Portenkirchner C, Nascimento I, Rossi NT, da Silva LA, Thomas H, Zarand A, Mecklin JP, Pylvanainen K, Renkonen-Sinisalo L, Lepisto A, Peltomaki P, Therkildsen C, Lindberg LJ, Thorlacius-Ussing O, von Knebel Doeberitz M, Loeffler M, Rahner N, Steinke-Lange V, Schmiegel W, Vangala D, Perne C, Huneburg R, de Vargas AF, Latchford A, Gerdes AM, Backman AS, Guillen-Ponce C, Snyder C, Lautrup CK, Amor D, Palmero E, Stoffel E, Duijkers F, Hall MJ, Hampel H, Williams H, Okkels H, Lubinski J, Reece J, Ngeow J, Guillem JG, Arnold J, Wadt K, Monahan K, Senter L, Rasmussen LJ, van Hest LP, Ricciardiello L, Kohonen-Corish MRJ, Ligtenberg MJL, Southey M, Aronson M, Zahary MN, Samadder NJ, Poplawski N, Hoogerbrugge N, Morrison PJ, James P, Lee G, Chen-Shtoyerman R, Ankathil R, Pai R, Ward R, Parry S, Debniak T, John T, van Overeem Hansen T, Caldes T, Yamaguchi T, Barca-Tierno V, Garre P, Cavestro GM, Weitz J, Redler S, Buttner R, Heuveline V, Hopper JL, Win AK, Lindor N, Gallinger S, Le Marchand L, Newcomb PA, Figueiredo J, Buchanan DD, Thibodeau SN, Ten Broeke SW, Hovig E, Nakken S, Pineda M, Duenas N, Brunet J, Green K, Lalloo F, Newton K, Crosbie EJ, Mints M, Tjandra D, Neffa F, Esperon P, Kariv R, Rosner G, Pavicic WH, Kalfayan P, Torrezan GT, Bassaneze T, Martin C, Moslein G, Ahadova A, Kloor M, Sampson JR, Jenkins MA. Colorectal cancer incidences in Lynch syndrome: a comparison of results from the prospective lynch syndrome database and the international mismatch repair consortium. Hered Cancer Clin Pract 20(1):36, 2022. e-Pub 2022. PMID: 36182917.
      25. Maida M, Annibale B, Benedetti A, Burra P, Frulloni L, Ianiro G, Luzza F, Repici A, Savarino E, Sinagra E, Vecchi M, Ricciardiello L. Quality of endoscopic screening for colorectal cancer in Italy: A national survey. Dig Liver Dis 54(10):1410-1418, 2022. e-Pub 2022. PMID: 35753948.
      26. Romano, M, Gravina, AG, Eusebi, LH, Pellegrino, R, Palladino, G, Frazzoni, L, Dajti, E, Gasbarrini, A, Di Mario, F, Zagari, RM, Benedetti, A, Annibale, B, Burra, P, Maida, M, Luzza, F, Ricciardiello, L, Vecchi, M, Frulloni, L, Repici, A, Savarino, E, Pasquale, L, Pisani, A, Lamazza, A, Cengia, G, Ciliberto, E, Conigliaro, RL, Da Massa Carrara, P, Germanà, B. Management of Helicobacter pylori infection. Digestive and Liver Disease 54(9):1153-1161, 2022. e-Pub 2022. PMID: 35831212.
      27. Rose TC, Pennington A, Kypridemos C, Chen T, Subhani M, Hanefeld J, Ricciardiello L, Barr B. Analysis of the burden and economic impact of digestive diseases and investigation of research gaps and priorities in the field of digestive health in the European Region-White Book 2: Executive summary. United European Gastroenterol J 10(7):657-662, 2022. e-Pub 2022. PMID: 36093599.
      28. Mengucci C, Nissen L, Picone G, Malpuech-Brugere C, Orfila C, Ricciardiello L, Bordoni A, Capozzi F, Gianotti A. K-Clique Multiomics Framework: A Novel Protocol to Decipher the Role of Gut Microbiota Communities in Nutritional Intervention Trials. Metabolites 12(8), 2022. e-Pub 2022. PMID: 36005608.
      29. Burra P, Bretthauer M, Buti Ferret M, Dugic A, Fracasso P, Leja M, Matysiak Budnik T, Michl P, Ricciardiello L, Seufferlein T, van Leerdam M, Botos A. Digestive cancer screening across Europe. United European Gastroenterol J 10(4):435-437, 2022. e-Pub 2022. PMID: 35474447.
      30. Filitto G, Coppola F, Curti N, Giampieri E, Dall'Olio D, Merlotti A, Cattabriga A, Cocozza MA, Taninokuchi Tomassoni M, Remondini D, Pierotti L, Strigari L, Cuicchi D, Guido A, Rihawi K, D'Errico A, Di Fabio F, Poggioli G, Morganti AG, Ricciardiello L, Golfieri R, Castellani G. Automated Prediction of the Response to Neoadjuvant Chemoradiotherapy in Patients Affected by Rectal Cancer. Cancers (Basel) 14(9), 2022. e-Pub 2022. PMID: 35565360.
      31. Montale A, Buttitta F, Pierantoni C, Ferrari C, Cameletti M, Colussi D, Miccoli S, Bazzoli F, Turchetti D, Ricciardiello L. Chromoendoscopy Is Not Superior to White Light Endoscopy in Improving Adenoma Detection in Lynch Syndrome Cohort Undergoing Surveillance with High-Resolution Colonoscopy: A Real-World Evidence Study. Dig Dis 40(4):517-525, 2022. e-Pub 2022. PMID: 34515093.
      32. Baldacchini, F, Bucchi, L, Giuliani, O, Mancini, S, Ravaioli, A, Vattiato, R, Giorgi Rossi, P, Campari, C, Canuti, D, Di Felice, E, Mezzetti, F, Sassoli de Bianchi, P, Ferretti, S, Falcini, F, Ventura, C, Colamartini, A, Signorelli, D, Aragona, G, Pennini, F, Chiaranda, G, Seghini, P, Fiora, CD, Fattibene, C, Michiara, M, Orsi, P, Mangone, L, Sassatelli, R, Carrozzi, G, Rossi, F, Esposito, P, Trande, P, Viani, S, Ricciardiello, L, Cennamo, V, Gualandi, G, Caprara, L, De Lillo, M, De Togni, A, Palmonari, C, Pasquali, D, Zoli, G, Re, SD, Petrini, C, Serafini, M, Triossi, O, Vitali, B, Gallinucci, M, Imolesi, C, Palazzi, M, Fabbri, C. Results of Compliant Participation in Five Rounds of Fecal Immunochemical Test Screening for Colorectal Cancer. Clinical Gastroenterology and Hepatology 19(11):2361-2369, 2021. e-Pub 2021. PMID: 32827723.
      33. Peck-Radosavljevic M, Burra P, Ferret MB, Fracasso P, Ricciardiello L, Seufferlein T, Van Hootegem P, van Leerdam M, Zelber-Sagi S. COVID-19 and digestive health: Implications for prevention, care and the use of COVID-19 vaccines in vulnerable patients. United European Gastroenterol J 9(9):1091-1095, 2021. e-Pub 2021. PMID: 34716760.
      34. Win, AK, Dowty, JG, Reece, JC, Lee, G, Templeton, AS, Plazzer, JP, Buchanan, D, Akagi, K, Aksoy, S, Alonso, Á, Alvarez, K, Amor, D, Ankathil, R, Aretz, S, Arnold, J, Aronson, M, Austin, R, Backman, AS, Ten Broeke, S, Barca-Tierno, V, Barwell, J, Bernstein, I, Berthet, P, Betz, B, Bignon, YJ, Boisjoli, T, Bonadona, V, Briollais, L, Brunet, J, Bucksch, K, Buecher, B, Büttner, R, Burn, J, Caldes, T, Capellá, G, Caron, O, Casey, G, Chew, MH, Choi, Yh, Church, J, Clendenning, M, Colas, C, Cops, EJ, Coupier, I, Cruz-Correa, M, Lynch, PM, Pande, M, Reis, RV, Ricciardiello, L, von Knebel Doeberitz, M. Variation in the risk of colorectal cancer in families with Lynch syndrome. The lancet oncology 22(7):1014-1022, 2021. e-Pub 2021. PMID: 34111421.
      35. Furnari M, Eusebi LH, Savarino E, Petruzzellis C, Esposito G, Maida M, Ricciardiello L, Pecere S, Buda A, De Bona M, Spada C, Di Giulio E, Costamagna G, Boskoski I, Giannini EG. Effects of SARS-CoV-2 emergency measures on high-risk lesions detection: a multicentre cross-sectional study. Gut 70(7):1241-1243, 2021. e-Pub 2021. PMID: 32989018.
      36. Buscarini E, Benedetti A, Monica F, Pasquale L, Buttitta F, Cameletti M, Ferrari C, Ricciardiello L. Changes in digestive cancer diagnosis during the SARS-CoV-2 pandemic in Italy: A nationwide survey. Dig Liver Dis 53(6):682-688, 2021. e-Pub 2021. PMID: 33726978.
      37. Coppola F, Mottola M, Lo Monaco S, Cattabriga A, Cocozza MA, Yuan JC, De Benedittis C, Cuicchi D, Guido A, Rojas Llimpe FL, D'Errico A, Ardizzoni A, Poggioli G, Strigari L, Morganti AG, Bazzoli F, Ricciardiello L, Golfieri R, Bevilacqua A. The Heterogeneity of Skewness in T2W-Based Radiomics Predicts the Response to Neoadjuvant Chemoradiotherapy in Locally Advanced Rectal Cancer. Diagnostics (Basel) 11(5), 2021. e-Pub 2021. PMID: 33924854.
      38. Danesi F, Mengucci C, Vita S, Bub A, Seifert S, Malpuech-Brugere C, Richard R, Orfila C, Sutulic S, Ricciardiello L, Marcato E, Capozzi F, Bordoni A. Unveiling the Correlation between Inadequate Energy/Macronutrient Intake and Clinical Alterations in Volunteers at Risk of Metabolic Syndrome by a Predictive Model. Nutrients 13(4), 2021. e-Pub 2021. PMID: 33923923.
      39. Ricciardiello L, Leja M, Ollivier M. Horizon Europe, the new programme for research & innovation: Which opportunities for GI research in the years to come?. United European Gastroenterol J 9(3):407-409, 2021. e-Pub 2021. PMID: 33939889.
      40. Cortellini F, Marasco G, Renzulli M, Vasuri F, Ricciardiello L. Gastric Melanoma of Unknown Primary. J Gastrointestin Liver Dis 30(1):14, 2021. e-Pub 2021. PMID: 33723546.
      41. Vanella G, Capurso G, Burti C, Fanti L, Ricciardiello L, Souza Lino A, Boskoski I, Bronswijk M, Tyberg A, Krishna Kumar Nair G, Angeletti S, Mauro A, Zingone F, Oppong KW, de la Iglesia-Garcia D, Pouillon L, Papanikolaou IS, Fracasso P, Ciceri F, Rovere-Querini P, Tomba C, Viale E, Eusebi LH, Riccioni ME, van der Merwe S, Shahid H, Sarkar A, Yoo JWG, Dilaghi E, Speight RA, Azzolini F, Buttitta F, Porcari S, Petrone MC, Iglesias-Garcia J, Savarino EV, Di Sabatino A, Di Giulio E, Farrell JJ, Kahaleh M, Roelandt P, Costamagna G, Artifon ELA, Bazzoli F, Testoni PA, Greco S, Arcidiacono PG. Gastrointestinal mucosal damage in patients with COVID-19 undergoing endoscopy: an international multicentre study. BMJ Open Gastroenterol 8(1), 2021. e-Pub 2021. PMID: 33627313.
      42. Innella G, Miccoli S, Colussi D, Pradella LM, Amato LB, Zuntini R, Salfi NCM, Collina G, Ferrara F, Ricciardiello L, Turchetti D. Colorectal polyposis as a clue to the diagnosis of Cowden syndrome: Report of two cases and literature review. Pathol Res Pract 218:153339, 2021. e-Pub 2021. PMID: 33482532.
      43. Laghi L, Ricciardiello L. The changing approach for identifying hereditary colorectal cancer syndromes. Nat Rev Gastroenterol Hepatol 17(10):593-594, 2020. e-Pub 2020. PMID: 32651554.
      44. Maida M, Sferrazza S, Savarino E, Ricciardiello L, Repici A, Morisco F, Furnari M, Fuccio L, Morreale GC, Vitello A, Burra P, Marchi S, Annibale B, Benedetti A, Alvaro D, Ianiro G. Impact of the COVID-19 pandemic on Gastroenterology Divisions in Italy: A national survey. Dig Liver Dis 52(8):808-815, 2020. e-Pub 2020. PMID: 32425733.
      45. Hassan C, Antonelli G, Dumonceau JM, Regula J, Bretthauer M, Chaussade S, Dekker E, Ferlitsch M, Gimeno-Garcia A, Jover R, Kalager M, Pellise M, Pox C, Ricciardiello L, Rutter M, Helsingen LM, Bleijenberg A, Senore C, van Hooft JE, Dinis-Ribeiro M, Quintero E. Post-polypectomy colonoscopy surveillance: European Society of Gastrointestinal Endoscopy (ESGE) Guideline - Update 2020. Endoscopy 52(8):687-700, 2020. e-Pub 2020. PMID: 32572858.
      46. Frazzoni L, Laterza L, Mussetto A, Zagari RM, Trovato C, De Bellis M, Paggi S, Piccirelli S, Ricciardiello L, Cesaro P, Spada C, Dal Piaz G, La Marca M, Fabbian F, Petrella L, Smania V, Marone P, Tatangelo F, Bazzoli F, Radaelli F, Repici A, Hassan C, Scagliarini M, Fuccio L. How to identify patients who are less likely to have metachronous neoplasms after a colon cancer: a predictive model. Endoscopy 52(3):220-226, 2020. e-Pub 2020. PMID: 31858510.
      47. Ghini V, Tenori L, Capozzi F, Luchinat C, Bub A, Malpuech-Brugere C, Orfila C, Ricciardiello L, Bordoni A. DHA-Induced Perturbation of Human Serum Metabolome. Role of the Food Matrix and Co-Administration of Oat beta-glucan and Anthocyanins. Nutrients 12(1), 2019. e-Pub 2019. PMID: 31892215.
      48. van Leerdam ME, Roos VH, van Hooft JE, Balaguer F, Dekker E, Kaminski MF, Latchford A, Neumann H, Ricciardiello L, Rupinska M, Saurin JC, Tanis PJ, Wagner A, Jover R, Pellise M. Endoscopic management of Lynch syndrome and of familial risk of colorectal cancer: European Society of Gastrointestinal Endoscopy (ESGE) Guideline. Endoscopy 51(11):1082-1093, 2019. e-Pub 2019. PMID: 31597170.
      49. van Leerdam ME, Roos VH, van Hooft JE, Dekker E, Jover R, Kaminski MF, Latchford A, Neumann H, Pellise M, Saurin JC, Tanis PJ, Wagner A, Balaguer F, Ricciardiello L. Endoscopic management of polyposis syndromes: European Society of Gastrointestinal Endoscopy (ESGE) Guideline. Endoscopy 51(9):877-895, 2019. e-Pub 2019. PMID: 31342472.
      50. Bub A, Malpuech-Brugere C, Orfila C, Amat J, Arianna A, Blot A, Di Nunzio M, Holmes M, Kertesz Z, Marshall L, Nemeth I, Ricciardiello L, Seifert S, Sutulic S, Ulaszewska M, Bordoni A. A Dietary Intervention of Bioactive Enriched Foods Aimed at Adults at Risk of Metabolic Syndrome: Protocol and Results from PATHWAY-27 Pilot Study. Nutrients 11(8), 2019. e-Pub 2019. PMID: 31390801.
      51. Enck P, Meisner S, Figueiredo C, Mayerle J, Ricciardiello L. Future research demands of the United European Gastroenterology (UEG) and its member societies. United European Gastroenterol J 7(6):859-863, 2019. e-Pub 2019. PMID: 31316790.
      52. Scaioli E, Belluzzi A, Ricciardiello L, Del Rio D, Rotondo E, Mena P, Derlindati E, Danesi F. Pomegranate juice to reduce fecal calprotectin levels in inflammatory bowel disease patients with a high risk of clinical relapse: Study protocol for a randomized controlled trial. Trials 20(1):327, 2019. e-Pub 2019. PMID: 31171016.
      53. Cavalleri T, Bianchi P, Basso G, Celesti G, Grizzi F, Bossi P, Greco L, Pitrone C, Valtorta E, Mauri G, Truini M, Dall'Olio FG, Brandi G, Sartore-Bianchi A, Ricciardiello L, Torri V, Rimassa L, Siena S, Mantovani A, Malesci A, Laghi L. Combined Low Densities of FoxP3(+) and CD3(+) Tumor-Infiltrating Lymphocytes Identify Stage II Colorectal Cancer at High Risk of Progression. Cancer Immunol Res 7(5):751-758, 2019. e-Pub 2019. PMID: 30804005.
      54. Hassan C, Senore C, Manes G, Fuccio L, Iacopini F, Ricciardiello L, Anderloni A, Frazzoni L, Ballanti R, de Nucci G, Colussi D, Redaelli D, Lorenzetti R, Devani M, Arena I, Grossi C, Andrei F, Balestrazzi E, Sharma P, Rex DK, Repici A. Diagnostic yield and miss rate of EndoRings in an organized colorectal cancer screening program: the SMART (Study Methodology for ADR-Related Technology) trial. Gastrointest Endosc 89(3):583-590.e1, 2019. e-Pub 2019. PMID: 30365984.
      55. Sartini A, Scaioli E, Liverani E, Bellanova M, Ricciardiello L, Bazzoli F, Belluzzi A. Retention Rate, Persistence and Safety of Adalimumab in Inflammatory Bowel Disease: A Real-Life, 9-Year, Single-Center Experience in Italy. Dig Dis Sci 64(3):863-874, 2019. e-Pub 2019. PMID: 30334112.
      56. Balzano A, Carle F, Tamburini C, Monica F, Milazzo G, Spolaore P, Galadini M, Basili F, Ricciardiello L, Buscarini E, Leandro G. Hospital admission for digestive diseases: Gastroenterology units offer a more effective and efficient care. Dig Liver Dis 51(1):43-46, 2019. e-Pub 2019. PMID: 30017656.
      57. Tavolari S, Deserti M, Vasuri F, Curti S, Palloni A, Pinna AD, Cescon M, Frega G, De Lorenzo S, Barbera MA, Garajova I, Ricciardiello L, Malvi D, D'Errico-Grigioni A, Pantaleo MA, Brandi G. Membrane human equilibrative nucleoside transporter 1 is associated with a high proliferation rate and worse survival in resected intrahepatic cholangiocarcinoma patients not receiving adjuvant treatments. Eur J Cancer 106:160-170, 2019. e-Pub 2019. PMID: 30528800.
      58. Piazzi G, Prossomariti A, Baldassarre M, Montagna C, Vitaglione P, Fogliano V, Biagi E, Candela M, Brigidi P, Balbi T, Munarini A, Belluzzi A, Pariali M, Bazzoli F, Ricciardiello L. A Mediterranean Diet Mix Has Chemopreventive Effects in a Murine Model of Colorectal Cancer Modulating Apoptosis and the Gut Microbiota. Front Oncol 9:140, 2019. e-Pub 2019. PMID: 30915275.
      59. Prossomariti A, Piazzi G, D'Angelo L, Miccoli S, Turchetti D, Alquati C, Montagna C, Bazzoli F, Ricciardiello L. miR-155 Is Downregulated in Familial Adenomatous Polyposis and Modulates WNT Signaling by Targeting AXIN1 and TCF4. Mol Cancer Res 16(12):1965-1976, 2018. e-Pub 2018. PMID: 30072583.
      60. Colussi D, Fabbri M, Zagari RM, Montale A, Bazzoli F, Ricciardiello L. Lifestyle factors and risk for colorectal polyps and cancer at index colonoscopy in a FIT-positive screening population. United European Gastroenterol J 6(6):935-942, 2018. e-Pub 2018. PMID: 30023072.
      61. Rodia MT, Solmi R, Pasini F, Nardi E, Mattei G, Ugolini G, Ricciardiello L, Strippoli P, Miglio R, Lauriola M. LGALS4, CEACAM6, TSPAN8, and COL1A2: Blood Markers for Colorectal Cancer-Validation in a Cohort of Subjects With Positive Fecal Immunochemical Test Result. Clin Colorectal Cancer 17(2):e217-e228, 2018. e-Pub 2018. PMID: 29352642.
      62. Ciavarella M, Miccoli S, Prossomariti A, Pippucci T, Bonora E, Buscherini F, Palombo F, Zuntini R, Balbi T, Ceccarelli C, Bazzoli F, Ricciardiello L, Turchetti D, Piazzi G. Somatic APC mosaicism and oligogenic inheritance in genetically unsolved colorectal adenomatous polyposis patients. Eur J Hum Genet 26(3):387-395, 2018. e-Pub 2018. PMID: 29367705.
      63. Prossomariti A, Scaioli E, Piazzi G, Fazio C, Bellanova M, Biagi E, Candela M, Brigidi P, Consolandi C, Balbi T, Chieco P, Munarini A, Pariali M, Minguzzi M, Bazzoli F, Belluzzi A, Ricciardiello L. Short-term treatment with eicosapentaenoic acid improves inflammation and affects colonic differentiation markers and microbiota in patients with ulcerative colitis. Sci Rep 7(1):7458, 2017. e-Pub 2017. PMID: 28785079.
      64. Toumi W, Ripalti A, Ricciardiello L, Cherif A, Gargouri D, Bouhafa A, Kharrat J, Jarboui S, Benrhouma H, Zili M, Khelifa R. Detection of a new JCV strain of genotype A in a subpopulation of colorectal adenocarcinomas in Tunisia. New Microbiol 40(2):99-106, 2017. e-Pub 2017. PMID: 28255604.
      65. Lynch PM, Morris JS, Wen S, Advani SM, Ross W, Chang GJ, Rodriguez-Bigas M, Raju GS, Ricciardiello L, Iwama T, Rossi BM, Pellise M, Stoffel E, Wise PE, Bertario L, Saunders B, Burt R, Belluzzi A, Ahnen D, Matsubara N, Bulow S, Jespersen N, Clark SK, Erdman SH, Markowitz AJ, Bernstein I, De Haas N, Syngal S, Moeslein G. A proposed staging system and stage-specific interventions for familial adenomatous polyposis. Gastrointest Endosc 84(1):115-125.e4, 2016. e-Pub 2016. PMID: 26769407.
      66. Fazio C, Piazzi G, Vitaglione P, Fogliano V, Munarini A, Prossomariti A, Milazzo M, D'Angelo L, Napolitano M, Chieco P, Belluzzi A, Bazzoli F, Ricciardiello L. Inflammation increases NOTCH1 activity via MMP9 and is counteracted by Eicosapentaenoic Acid-free fatty acid in colon cancer cells. Sci Rep 6:20670, 2016. e-Pub 2016. PMID: 26864323.
      67. Colussi D, Salari B, Stewart KO, Lauwers GY, Richter JR, Chan AT, Ricciardiello L, Khalili H. Clinical characteristics and patterns and predictors of response to therapy in collagenous and lymphocytic colitis. Scand J Gastroenterol 50(11):1382-8, 2015. e-Pub 2015. PMID: 25997458.
      68. Piazzi G, D'Argenio G, Prossomariti A, Lembo V, Mazzone G, Candela M, Biagi E, Brigidi P, Vitaglione P, Fogliano V, D'Angelo L, Fazio C, Munarini A, Belluzzi A, Ceccarelli C, Chieco P, Balbi T, Loadman PM, Hull MA, Romano M, Bazzoli F, Ricciardiello L. Eicosapentaenoic acid free fatty acid prevents and suppresses colonic neoplasia in colitis-associated colorectal cancer acting on Notch signaling and gut microbiota. Int J Cancer 135(9):2004-13, 2014. e-Pub 2014. PMID: 24676631.
      69. D'Angelo L, Piazzi G, Pacilli A, Prossomariti A, Fazio C, Montanaro L, Graziani G, Fogliano V, Munarini A, Bianchi F, Belluzzi A, Bazzoli F, Ricciardiello L. A combination of eicosapentaenoic acid-free fatty acid, epigallocatechin-3-gallate and proanthocyanidins has a strong effect on mTOR signaling in colorectal cancer cells. Carcinogenesis 35(10):2314-20, 2014. e-Pub 2014. PMID: 25123131.
      70. Piazzi G, Selgrad M, Garcia M, Ceccarelli C, Fini L, Bianchi P, Laghi L, D'Angelo L, Paterini P, Malfertheiner P, Chieco P, Boland CR, Bazzoli F, Ricciardiello L. Van-Gogh-like 2 antagonises the canonical WNT pathway and is methylated in colorectal cancers. Br J Cancer 108(8):1750-6, 2013. e-Pub 2013. PMID: 23579212.
      71. De Luca L, Ricciardiello L, Rocchi MB, Fabi MT, Bianchi ML, de Leone A, Fiori S, Baroncini D. Narrow band imaging with magnification endoscopy for celiac disease: results from a prospective, single-center study. Diagn Ther Endosc 2013:580526, 2013. e-Pub 2013. PMID: 23983448.
      72. Federico A, Nardone G, Gravina AG, Iovene MR, Miranda A, Compare D, Pilloni PA, Rocco A, Ricciardiello L, Marmo R, Loguercio C, Romano M. Efficacy of 5-day levofloxacin-containing concomitant therapy in eradication of Helicobacter pylori infection. Gastroenterology 143(1):55-61.e1; quize e13-4, 2012. e-Pub 2012. PMID: 22484118.
      73. Piazzi G, Fini L, Selgrad M, Garcia M, Daoud Y, Wex T, Malfertheiner P, Gasbarrini A, Romano M, Meyer RL, Genta RM, Fox JG, Boland CR, Bazzoli F, Ricciardiello L. Epigenetic regulation of Delta-Like1 controls Notch1 activation in gastric cancer. Oncotarget 2(12):1291-301, 2011. e-Pub 2011. PMID: 22249198.
      74. Ricciardiello L, Bazzoli F, Fogliano V. Phytochemicals and colorectal cancer prevention--myth or reality?. Nat Rev Gastroenterol Hepatol 8(10):592-6, 2011. e-Pub 2011. PMID: 21894197.
      75. Fini L, Piazzi G, Daoud Y, Selgrad M, Maegawa S, Garcia M, Fogliano V, Romano M, Graziani G, Vitaglione P, Carmack SW, Gasbarrini A, Genta RM, Issa JP, Boland CR, Ricciardiello L. Chemoprevention of intestinal polyps in ApcMin/+ mice fed with western or balanced diets by drinking annurca apple polyphenol extract. Cancer Prev Res (Phila) 4(6):907-15, 2011. e-Pub 2011. PMID: 21383028.
      76. De Luca L, Ricciardiello L, Modugno P, De Filippo CM, Baroncini D. Lethal nature of ischemic gastropathy: a case report of celiomesenteric vascular insufficiency. Clin J Gastroenterol 4(2):60-3, 2011. e-Pub 2011. PMID: 26190706.
      77. Fini L, Piazzi G, Ceccarelli C, Daoud Y, Belluzzi A, Munarini A, Graziani G, Fogliano V, Selgrad M, Garcia M, Gasbarrini A, Genta RM, Boland CR, Ricciardiello L. Highly purified eicosapentaenoic acid as free fatty acids strongly suppresses polyps in Apc(Min/+) mice. Clin Cancer Res 16(23):5703-11, 2010. e-Pub 2010. PMID: 21030497.
      78. De Giorgio R, Ricciardiello L, Naponelli V, Selgrad M, Piazzi G, Felicani C, Serra M, Fronzoni L, Antonucci A, Cogliandro RF, Barbara G, Corinaldesi R, Tonini M, Knowles CH, Stanghellini V. Chronic intestinal pseudo-obstruction related to viral infections. Transplant Proc 42(1):9-14, 2010. e-Pub 2010. PMID: 20172270.
      79. Selgrad M, De Giorgio R, Fini L, Cogliandro RF, Williams S, Stanghellini V, Barbara G, Tonini M, Corinaldesi R, Genta RM, Domiati-Saad R, Meyer R, Goel A, Boland CR, Ricciardiello L. JC virus infects the enteric glia of patients with chronic idiopathic intestinal pseudo-obstruction. Gut 58(1):25-32, 2009. e-Pub 2009. PMID: 18593810.
      80. Selgrad M, Koornstra JJ, Fini L, Blom M, Huang R, Devol EB, Boersma-van Ek W, Dijkstra G, Verdonk RC, de Jong S, Goel A, Williams SL, Meyer RL, Haagsma EB, Ricciardiello L, Boland CR. JC virus infection in colorectal neoplasia that develops after liver transplantation. Clin Cancer Res 14(20):6717-21, 2008. e-Pub 2008. PMID: 18927316.
      81. Fini L, Hotchkiss E, Fogliano V, Graziani G, Romano M, De Vol EB, Qin H, Selgrad M, Boland CR, Ricciardiello L. Chemopreventive properties of pinoresinol-rich olive oil involve a selective activation of the ATM-p53 cascade in colon cancer cell lines. Carcinogenesis 29(1):139-46, 2008. e-Pub 2008. PMID: 17999988.
      82. Fini L, Selgrad M, Fogliano V, Graziani G, Romano M, Hotchkiss E, Daoud YA, De Vol EB, Boland CR, Ricciardiello L. Annurca apple polyphenols have potent demethylating activity and can reactivate silenced tumor suppressor genes in colorectal cancer cells. J Nutr 137(12):2622-8, 2007. e-Pub 2007. PMID: 18029474.
      83. Goel A, Li MS, Nagasaka T, Shin SK, Fuerst F, Ricciardiello L, Wasserman L, Boland CR. Association of JC virus T-antigen expression with the methylator phenotype in sporadic colorectal cancers. Gastroenterology 130(7):1950-61, 2006. e-Pub 2006. PMID: 16762618.
      84. Perri F, Piepoli A, Bonvicini C, Gentile A, Quitadamo M, Di Candia M, Cotugno R, Cattaneo F, Zagari MR, Ricciardiello L, Gennarelli M, Bazzoli F, Ranzani GN, Andriulli A. Cytokine gene polymorphisms in gastric cancer patients from two Italian areas at high and low cancer prevalence. Cytokine 30(5):293-302, 2005. e-Pub 2005. PMID: 15927855.
      85. Ricciardiello L, Ceccarelli C, Angiolini G, Pariali M, Chieco P, Paterini P, Biasco G, Martinelli GN, Roda E, Bazzoli F. High thymidylate synthase expression in colorectal cancer with microsatellite instability: implications for chemotherapeutic strategies. Clin Cancer Res 11(11):4234-40, 2005. e-Pub 2005. PMID: 15930362.
      86. De Luca L, Zagari RM, Pozzato P, Fiorini T, Ricciardiello L, Martuzzi C, Roda E, Bazzoli F, van Zanten SJ. Measuring dyspepsia: a new severity index validated in Bologna. Dig Liver Dis 36(12):806-10, 2004. e-Pub 2004. PMID: 15646426.
      87. Ricciardiello L, Baglioni M, Giovannini C, Pariali M, Cenacchi G, Ripalti A, Landini MP, Sawa H, Nagashima K, Frisque RJ, Goel A, Boland CR, Tognon M, Roda E, Bazzoli F. Induction of chromosomal instability in colonic cells by the human polyomavirus JC virus. Cancer Res 63(21):7256-62, 2003. e-Pub 2003. PMID: 14612521.
      88. Chang DK, Goel A, Ricciardiello L, Lee DH, Chang CL, Carethers JM, Boland CR. Effect of H(2)O(2) on cell cycle and survival in DNA mismatch repair-deficient and -proficient cell lines. Cancer Lett 195(2):243-51, 2003. e-Pub 2003. PMID: 12767533.
      89. Goel A, Arnold CN, Niedzwiecki D, Chang DK, Ricciardiello L, Carethers JM, Dowell JM, Wasserman L, Compton C, Mayer RJ, Bertagnolli MM, Boland CR. Characterization of sporadic colon cancer by patterns of genomic instability. Cancer Res 63(7):1608-14, 2003. e-Pub 2003. PMID: 12670912.
      90. Ricciardiello L, Goel A, Mantovani V, Fiorini T, Fossi S, Chang DK, Lunedei V, Pozzato P, Zagari RM, De Luca L, Fuccio L, Martinelli GN, Roda E, Boland CR, Bazzoli F. Frequent loss of hMLH1 by promoter hypermethylation leads to microsatellite instability in adenomatous polyps of patients with a single first-degree member affected by colon cancer. Cancer Res 63(4):787-92, 2003. e-Pub 2003. PMID: 12591727.
      91. Goel A, Chang DK, Ricciardiello L, Gasche C, Boland CR. A novel mechanism for aspirin-mediated growth inhibition of human colon cancer cells. Clin Cancer Res 9(1):383-90, 2003. e-Pub 2003. PMID: 12538492.
      92. Chang CL, Marra G, Chauhan DP, Ha HT, Chang DK, Ricciardiello L, Randolph A, Carethers JM, Boland CR. Oxidative stress inactivates the human DNA mismatch repair system. Am J Physiol Cell Physiol 283(1):C148-54, 2002. e-Pub 2002. PMID: 12055083.
      93. Lunedei V, Bazzoli F, Pozzato P, De Luca L, Zagari RM, Fossi S, Ricciardiello L, Maltoni S, Roda E. Endoscopic surveillance in Barrett's esophagus. Minerva Gastroenterol Dietol 48(2):63-71, 2002. e-Pub 2002. PMID: 16489297.
      94. Bazzoli F, Zagari RM, Pozzato P, Fossi S, Ricciardiello L, Nicolini G, De Luca L, Berretti D, Alampi G, Di Pietro C, Morelli P, Roda E. Low-dose lansoprazole and clarithromycin plus metronidazole vs. full-dose lansoprazole and clarithromycin plus amoxicillin for eradication of Helicobacter pylori infection. Aliment Pharmacol Ther 16(1):153-8, 2002. e-Pub 2002. PMID: 11856090.
      95. Bazzoli F, Palli D, Zagari RM, Festi D, Pozzato P, Nicolini G, Masala G, Fossi S, Ricciardiello L, Panuccio D, Roda E. The Loiano-Monghidoro population-based study of Helicobacter pylori infection: prevalence by 13C-urea breath test and associated factors. Aliment Pharmacol Ther 15(7):1001-7, 2001. e-Pub 2001. PMID: 11421875.
      96. Fossi S, Bazzoli F, Ricciardiello L, Nicolini G, Zagari RM, Pozzato P, Palli D, Roda E. Incidence and recurrence rates of colorectal adenomas in first-degree asymptomatic relatives of patients with colon cancer. Am J Gastroenterol 96(5):1601-4, 2001. e-Pub 2001. PMID: 11374706.
      97. Ricciardiello L, Chang DK, Laghi L, Goel A, Chang CL, Boland CR. Mad-1 is the exclusive JC virus strain present in the human colon, and its transcriptional control region has a deleted 98-base-pair sequence in colon cancer tissues. J Virol 75(4):1996-2001, 2001. e-Pub 2001. PMID: 11160700.
      98. Huang SC, Chen CR, Lavine JE, Taylor SF, Newbury RO, Pham TT, Ricciardiello L, Carethers JM. Genetic heterogeneity in familial juvenile polyposis. Cancer Res 60(24):6882-5, 2000. e-Pub 2000. PMID: 11156385.
      99. Ricciardiello L, Laghi L, Ramamirtham P, Chang CL, Chang DK, Randolph AE, Boland CR. JC virus DNA sequences are frequently present in the human upper and lower gastrointestinal tract. Gastroenterology 119(5):1228-35, 2000. e-Pub 2000. PMID: 11054380.
      100. Chang DK, Ricciardiello L, Goel A, Chang CL, Boland CR. Steady-state regulation of the human DNA mismatch repair system. J Biol Chem 275(37):29178, 2000. e-Pub 2000. PMID: 10979986.
      101. Chang DK, Ricciardiello L, Goel A, Chang CL, Boland CR. Steady-state regulation of the human DNA mismatch repair system. J Biol Chem 275(24):18424-31, 2000. e-Pub 2000. PMID: 10747992.
      102. Bazzoli F, Cecchini L, Corvaglia L, Dall'Antonia M, De Giacomo C, Fossi S, Casali LG, Gullini S, Lazzari R, Leggeri G, Lerro P, Valdambrini V, Mandrioli G, Marani M, Martelli P, Miano A, Nicolini G, Oderda G, Pazzi P, Pozzato P, Ricciardiello L, Roda E, Simoni P, Sottili S, Zagari RM. Validation of the 13C-urea breath test for the diagnosis of Helicobacter pylori infection in children: a multicenter study. Am J Gastroenterol 95(3):646-50, 2000. e-Pub 2000. PMID: 10710052.
      103. Boland CR, Ricciardiello L. How many mutations does it take to make a tumor?. Proc Natl Acad Sci U S A 96(26):14675-7, 1999. e-Pub 1999. PMID: 10611270.
      104. Ricciardiello L, Cannizzaro O, D'Angelo A, Ederle A, Gerace G, Iaquinto G, Reina G, Scarpulla G, Spadaccini A, Olivieri A, Tosatto R, Fossi S, Pozzato P, Zagari M, Bazzoli F, Roda E. Efficacy and safety of three 7-day Helicobacter pylori eradication regimens containing ranitidine bismuth citrate. Aliment Pharmacol Ther 12(6):533-7, 1998. e-Pub 1998. PMID: 9678812.
      105. Bazzoli F, Zagari M, Pozzato P, Varoli O, Fossi S, Ricciardiello L, Alampi G, Nicolini G, Sottili S, Simoni P, Roda A, Roda E. Evaluation of short-term low-dose triple therapy for the eradication of Helicobacter pylori by factorial design in a randomized, double-blind, controlled study. Aliment Pharmacol Ther 12(5):439-45, 1998. e-Pub 1998. PMID: 9663723.
      106. Malfertheiner P, McColl K, Baldi F, Dinelli M, Festi D, Parente F, Ricciardiello L, Roda E, Scarpulla G, Stanghellini V, Torre G. Update on Helicobacter pylori research. Dyspepsia. Eur J Gastroenterol Hepatol 9(6):624-5, 1997. e-Pub 1997. PMID: 9222740.

      Review Articles

      1. Greco L, Rubbino F, Ferrari C, Cameletti M, Grizzi F, Bonelli F, Malesci A, Mazzone M, Ricciardiello L, Laghi L. Association of Fusobacterium nucleatum with colorectal cancer molecular subtypes and its outcome: a systematic review. Gut Microbiome (Camb) 6:e5, 2025. e-Pub 2025. PMID: 40297307.
      2. Zaffaroni G, Mannucci A, Koskenvuo L, de Lacy B, Maffioli A, Bisseling T, Half E, Cavestro GM, Valle L, Ryan N, Aretz S, Brown K, Buttitta F, Carneiro F, Claber O, Blanco-Colino R, Collard M, Crosbie E, Cunha M, Doulias T, Fleming C, Heinrich H, Huneburg R, Metras J, Nagtegaal I, Negoi I, Nielsen M, Pellino G, Ricciardiello L, Sagir A, Sanchez-Guillen L, Seppala TT, Siersema P, Striebeck B, Sampson JR, Latchford A, Parc Y, Burn J, Moslein G. Updated European guidelines for clinical management of familial adenomatous polyposis (FAP), MUTYH-associated polyposis (MAP), gastric adenocarcinoma, proximal polyposis of the stomach (GAPPS) and other rare adenomatous polyposis syndromes: a joint EHTG-ESCP revision. Br J Surg 111(5), 2024. e-Pub 2024. PMID: 38722804.
      3. Pierantoni C, Cosentino L, Ricciardiello L. Molecular Pathways of Colorectal Cancer Development: Mechanisms of Action and Evolution of Main Systemic Therapy Compunds. Dig Dis 42(4):319-324, 2024. e-Pub 2024. PMID: 38531339.
      4. Aelvoet AS, Buttitta F, Ricciardiello L, Dekker E. Management of familial adenomatous polyposis and MUTYH-associated polyposis; new insights. Best Pract Res Clin Gastroenterol 58-59:101793, 2022. e-Pub 2022. PMID: 35988966.
      5. Michl P, Lohr M, Neoptolemos JP, Capurso G, Rebours V, Malats N, Ollivier M, Ricciardiello L. UEG position paper on pancreatic cancer. Bringing pancreatic cancer to the 21st century: Prevent, detect, and treat the disease earlier and better. United European Gastroenterol J 9(7):860-871, 2021. e-Pub 2021. PMID: 34431604.
      6. Alquati C, Prossomariti A, Piazzi G, Buttitta F, Bazzoli F, Laghi L, Ricciardiello L. Discovering the Mutational Profile of Early Colorectal Lesions: A Translational Impact. Cancers (Basel) 13(9), 2021. e-Pub 2021. PMID: 33923068.
      7. Ferlizza E, Solmi R, Sgarzi M, Ricciardiello L, Lauriola M. The Roadmap of Colorectal Cancer Screening. Cancers (Basel) 13(5):1-20, 2021. e-Pub 2021. PMID: 33806465.
      8. Prossomariti A, Piazzi G, Alquati C, Ricciardiello L. Are Wnt/beta-Catenin and PI3K/AKT/mTORC1 Distinct Pathways in Colorectal Cancer?. Cell Mol Gastroenterol Hepatol 10(3):491-506, 2020. e-Pub 2020. PMID: 32334125.
      9. Prossomariti A, Sokol H, Ricciardiello L. Nucleotide-Binding Domain Leucine-Rich Repeat Containing Proteins and Intestinal Microbiota: Pivotal Players in Colitis and Colitis-Associated Cancer Development. Front Immunol 9:1039, 2018. e-Pub 2018. PMID: 29868004.
      10. Fazio C, Ricciardiello L. Inflammation and Notch signaling: a crosstalk with opposite effects on tumorigenesis. Cell Death Dis 7(12):e2515, 2016. e-Pub 2016. PMID: 27929540.
      11. Ricciardiello L, Ahnen DJ, Lynch PM. Chemoprevention of hereditary colon cancers: time for new strategies. Nat Rev Gastroenterol Hepatol 13(6):352-61, 2016. e-Pub 2016. PMID: 27095653.
      12. Block KI, Gyllenhaal C, Lowe L, Amedei A, Amin ARMR, Amin A, Aquilano K, Arbiser J, Arreola A, Arzumanyan A, Ashraf SS, Azmi AS, Benencia F, Bhakta D, Bilsland A, Bishayee A, Blain SW, Block PB, Boosani CS, Carey TE, Carnero A, Carotenuto M, Casey SC, Chakrabarti M, Chaturvedi R, Chen GZ, Chen H, Chen S, Chen YC, Choi BK, Ciriolo MR, Coley HM, Collins AR, Connell M, Crawford S, Curran CS, Dabrosin C, Damia G, Dasgupta S, DeBerardinis RJ, Decker WK, Dhawan P, Diehl AME, Dong JT, Dou QP, Drew JE, Elkord E, El-Rayes B, Feitelson MA, Felsher DW, Ferguson LR, Fimognari C, Firestone GL, Frezza C, Fujii H, Fuster MM, Generali D, Georgakilas AG, Gieseler F, Gilbertson M, Green MF, Grue B, Guha G, Halicka D, Helferich WG, Heneberg P, Hentosh P, Hirschey MD, Hofseth LJ, Holcombe RF, Honoki K, Hsu HY, Huang GS, Jensen LD, Jiang WG, Jones LW, Karpowicz PA, Keith WN, Kerkar SP, Khan GN, Khatami M, Ko YH, Kucuk O, Kulathinal RJ, Kumar NB, Kwon BS, Le A, Lea MA, Lee HY, Lichtor T, Lin LT, Locasale JW, Lokeshwar BL, Longo VD, Lyssiotis CA, MacKenzie KL, Malhotra M, Marino M, Martinez-Chantar ML, Matheu A, Maxwell C, McDonnell E, Meeker AK, Mehrmohamadi M, Mehta K, Michelotti GA, Mohammad RM, Mohammed SI, Morre DJ, Muralidhar V, Muqbil I, Murphy MP, Nagaraju GP, Nahta R, Niccolai E, Nowsheen S, Panis C, Pantano F, Parslow VR, Pawelec G, Pedersen PL, Poore B, Poudyal D, Prakash S, Prince M, Raffaghello L, Rathmell JC, Rathmell WK, Ray SK, Reichrath J, Rezazadeh S, Ribatti D, Ricciardiello L, Robey RB, Rodier F, Rupasinghe HPV, Russo GL, Ryan EP, Samadi AK, Sanchez-Garcia I, Sanders AJ, Santini D, Sarkar M, Sasada T, Saxena NK, Shackelford RE, Shantha Kumara HMC, Sharma D, Shin DM, Sidransky D, Siegelin MD, Signori E, Singh N, Sivanand S, Sliva D, Smythe C, Spagnuolo C, Stafforini DM, Stagg J, Subbarayan PR, Sundin T, Talib WH, Thompson SK, Tran PT, Ungefroren H, Vander Heiden MG, Venkateswaran V, Vinay DS, Vlachostergios PJ, Wang Z, Wellen KE, Whelan RL, Yang ES, Yang H, Yang X, Yaswen P, Yedjou C, Yin X, Zhu J, Zollo M. Designing a broad-spectrum integrative approach for cancer prevention and treatment. Semin Cancer Biol 35 Suppl(Suppl):S276-S304, 2015. e-Pub 2015. PMID: 26590477.
      13. Samadi AK, Bilsland A, Georgakilas AG, Amedei A, Amin A, Bishayee A, Azmi AS, Lokeshwar BL, Grue B, Panis C, Boosani CS, Poudyal D, Stafforini DM, Bhakta D, Niccolai E, Guha G, Vasantha Rupasinghe HP, Fujii H, Honoki K, Mehta K, Aquilano K, Lowe L, Hofseth LJ, Ricciardiello L, Ciriolo MR, Singh N, Whelan RL, Chaturvedi R, Ashraf SS, Shantha Kumara HMC, Nowsheen S, Mohammed SI, Keith WN, Helferich WG, Yang X. A multi-targeted approach to suppress tumor-promoting inflammation. Semin Cancer Biol 35 Suppl:S151-S184, 2015. e-Pub 2015. PMID: 25951989.
      14. Aleman JO, Eusebi LH, Ricciardiello L, Patidar K, Sanyal AJ, Holt PR. Mechanisms of obesity-induced gastrointestinal neoplasia. Gastroenterology 146(2):357-373, 2014. e-Pub 2014. PMID: 24315827.
      15. Colussi D, Brandi G, Bazzoli F, Ricciardiello L. Molecular pathways involved in colorectal cancer: implications for disease behavior and prevention. Int J Mol Sci 14(8):16365-85, 2013. e-Pub 2013. PMID: 23965959.
      16. Piazzi G, Bazzoli F, Ricciardiello L. Epigenetic silencing of Notch signaling in gastrointestinal cancers. Cell Cycle 11(23):4323-7, 2012. e-Pub 2012. PMID: 23085543.
      17. Solimando R, Bazzoli F, Ricciardiello L. Chemoprevention of colorectal cancer: a role for ursodeoxycholic acid, folate and hormone replacement treatment?. Best Pract Res Clin Gastroenterol 25(4-5):555-68, 2011. e-Pub 2011. PMID: 22122771.
      18. Selgrad M, Malfertheiner P, Fini L, Goel A, Boland CR, Ricciardiello L. The role of viral and bacterial pathogens in gastrointestinal cancer. J Cell Physiol 216(2):378-88, 2008. e-Pub 2008. PMID: 18338378.
      19. Ricciardiello L, Boland CR. Lynch syndrome (hereditary non-polyposis colorectal cancer): current concepts and approaches to management. Curr Gastroenterol Rep 7(5):412-20, 2005. e-Pub 2005. PMID: 16168241.
      20. Bazzoli F, De Luca L, Pozzato P, Zagari RM, Fossi S, Ricciardiello L, Nicolini G, Berretti D, Roda E. Helicobacter pylori and functional dyspepsia: review of previous studies and commentary on new data. Gut 50 Suppl 4(Suppl 4):iv33-5, 2002. e-Pub 2002. PMID: 11953345.
      21. Ricciardiello L, Bazzoli F. The role of genomic instabilities in affecting treatment responses of colorectal cancer. Dig Dis 20(1):73-80, 2002. e-Pub 2002. PMID: 12145423.
      22. Ricciardiello L, Roda E, Bazzoli F. Chemoprevention in colorectal neoplasias: what is practical and feasible?. Dig Dis 20(1):70-2, 2002. e-Pub 2002. PMID: 12145422.
      23. Bazzoli F, Zagari RM, Pozzato P, Fossi S, Ricciardiello L, De Luca L, Nicolini G, Berretti D, Maltoni S, Gorini B, Martuzzi C, Fuccio L, Roda E. Helicobacter pylori: optimum diagnosis and test of cure. J Chemother 11(6):601-5, 1999. e-Pub 1999. PMID: 10678806.
      24. Bazzoli F, Zagari M, Fossi S, Pozzato P, Ricciardiello L, Mwangemi C, Roda A, Roda E. Urea breath tests for the detection of Helicobacter pylori infection. Helicobacter 2 Suppl 1:S34-7, 1997. e-Pub 1997. PMID: 9432352.

      Other Articles

      1. Chandrapalan S, Bosch S, Cubiella J, Guardiola J, Kimani P, Mulder C, Persaud K, de Meij TGJ, Altomare DF, Brenner H, de Boer NKH, Ricciardiello L, Arasaradnam RP Systematic review with meta-analysis: volatile organic compound analysis to improve faecal immunochemical testing in the detection of colorectal cancer. Aliment Pharmacol Ther 54(1):14-23, 2021. PMID: 34004036.
      2. Ricciardiello L, Ferrari C, Cameletti M, Gaianill F, Buttitta F, Bazzoli F, Luigi de'Angelis G, Malesci A, Laghi L Impact of SARS-CoV-2 Pandemic on Colorectal Cancer Screening Delay: Effect on Stage Shift and Increased Mortality. Clin Gastroenterol Hepatol 19(7):1410-1417.e9, 2021. PMID: 32898707.
      3. Bazzoli F, Pozzato P, Zagari M, Fossi S, Ricciardiello L, Nicolini G, Berretti D, De Luca L Efficacy of lansoprazole in eradicating Helicobacter pylori: a meta-analysis. Helicobacter 3(3):195-201, 1998. PMID: 9731991.

      Editorials

      1. Pritchard CC, Ricciardiello L. Establishing Adenoma Testing Guidelines for Diagnosing Mosaicism. Gastroenterology 170(5):882-884, 2026. PMID: 41654092.
      2. Ricciardiello L. Digestive diseases: Big burden, low funding? Results of the new United European Gastroenterology White Book on digestive diseases. United European Gastroenterol J 10(7):627-628, 2022. PMID: 36017606.
      3. van Leerdam ME, Ricciardiello L. Preface Hereditary disorders. Best Pract Res Clin Gastroenterol 58-59:101801, 2022. PMID: 35988961.
      4. Chandrapalan S, Bosch S, Tyagi H, Daulton E, Cubiella J, Guardiola J, Kimani P, Mulder C, Covington J, Persaud K, de Meij TGJ, Altomare DF, Brenner H, de Boer NKH, Ricciardiello L, Arasaradnam RP. Editorial: volatile organic compound analysis to improve faecal immunochemical testing in the detection of colorectal cancer-Authors' reply. Aliment Pharmacol Ther 54(4):506-507, 2021. PMID: 34331793.
      5. Malfertheiner P, Bornschein J, Ricciardiello L. COVID-19: Don't Neglect the Gastrointestinal Tract!. Dig Dis 38(4):259-260, 2020. PMID: 32349002.

      Book Chapters

      1. Ricciardiello L, Principi. Neoplasie del Colonretto. In: Malattie dell' Apparato Digerente . Edizione 2022 - 2025. Edra, 2022.
      2. Ricciardiello L, Principi. Neoplasia del Colonretto. In: Malattie dell' Apparato Digerente . Edizione 2019 - 2022, 2019.
      3. Di Giulio, Ricciardiello L. Neoplasia del Colon Retto. In: Malattie dell' Apparato Digerente . Edizione 2016-2019, 2016.

      Letters to the Editor

      1. Laghi L, Cameletti M, Ferrari C, Ricciardiello L. Impairment of colorectal cancer screening during the COVID-19 pandemic. Lancet Gastroenterol Hepatol 6: 425-426, 2021.
      2. Belluzzi A, Scaioli E, Ricciardiello L, Marasco G, Belluzzi C. Eicosapentaenoic free fatty acid to treat patients with SARS-Cov2 infection. Med Hypotheses 143: 110095, 2020.
      3. Colussi D, Zagari RM, Morini B, Fabbri M, Montale A, Hassan C, Senore C, Bazzoli F, Ricciardiello L. Prevalence of serrated polyposis syndrome in an FIT-based colorectal cancer screening cohort in Italy. Gut 66: 1532-1533, 2017.
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