Michelle D. Williams, M.D.
Department of Anatomical Pathology, Division of Pathology-Lab Medicine Div
About Dr. Williams
Michelle D Williams, MD is a Professor in Anatomical Pathology and Section Chief for Head and Neck Pathology at The University of Texas MD Anderson Cancer Center and is a board-certified Anatomic and Clinical Pathologist. Dr. Williams has over 18 years of experience providing pathologic assessment of thyroid, parathyroid and head and neck cancers. Her expertise in endocrine and head and neck neoplasia is internationally recognized through involvement as a coauthor on The World Health Organization (WHO) Classification of Tumours: Pathology and Genetics of Endocrine and Head and Neck Tumour books. Clinical trials are also an interest of hers as the dedication thyroid pathologist during this historic time of advancing thyroid cancer treatments, as well as her dedication to trial and research reviews as Chair of one of MD Anderson Institutional Review Boards. Dr. Williams’s research collaborations span development of novel resources, including cell lines and PDX models through tissue collections, biomarker development, and neoadjuvant therapeutic pathologic assessments. Additionally, her work through multidisciplinary and multi-institutional collaborations utilizing optical imaging for enhancing oral neoplasia detection and machine learning continue to advance disease detection and future image-based personal therapy.
Present Title & Affiliation
Primary Appointment
Professor, Department of Pathology, Division of Pathology/Lab Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX
Education & Training
Degree-Granting Education
2000 | University of Florida College of Medicine, Gainesville, FL, USA, MD, Doctor of Medicine |
1996 | University of Central Florida, Orlando, FL, USA, BS, Molecular and Microbiology |
Postgraduate Training
2005-2006 | Fellowship, Head & Neck Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX |
2004-2005 | Fellowship, Surgical Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX |
2001-2004 | Residency, Anatomic and Clinical Pathology, University of Florida, Gainesville, FL |
Board Certifications
2005 | American Board of Pathology: Anatomical and Clinical |
Experience & Service
Academic Appointments
Associate Professor, Department of Pathology, Division of Pathology/Lab Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, 2012 - 2018
Assistant Professor, Department of Pathology, Division of Pathology/Lab Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, 2006 - 2012
Administrative Appointments/Responsibilities
Fellowship Program Director, Department of Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX, 2012 - 2014
Committee Vice Chair, Department of Office of Research Administration, Institutional Review Board, The University of Texas MD Anderson Cancer Center, Houston, TX, 2010 - 2019
Institutional Committee Activities
Associate, MDACC Cancer Network, 2014 - Present
Associate, CCSG- Head and Neck, 2007 - Present
Selected Publications
Peer-Reviewed Articles
- Wang JR, Zafereo ME, Cabanillas ME, Wu CC, Xu L, Dai Y, Wang W, Lai SY, Henderson Y, Erasmus L, Williams MD, Joshu C, Ray D. The association between thyroid differentiation score and survival outcomes in papillary thyroid carcinoma. J Clin Endocrinol Metab. e-Pub 2024. PMID: 39087944.
- Feldman HA, Busaidy NL, Tame-Elorduy A, Silva AK, Halfteck G, Merriman K, Waguespack SG, Graham PH, Williams MD, Perrier ND. Clinical course of atypical parathyroid neoplasm with soft tissue extension. J Surg Oncol. e-Pub 2024. PMID: 39155668.
- Hamidi S, Dadu R, Zafereo ME, Ferrarotto R, Wang JR, Maniakas A, Gunn GB, Lee A, Spiotto MT, Iyer PC, Sousa LG, Akhave NS, Ahmed S, Learned KO, Lu C, Lai SY, Williams M, Hosseini SM, Busaidy NL, Cabanillas ME. Initial Management of BRAF V600E-Variant Anaplastic Thyroid Cancer: The FAST Multidisciplinary Group Consensus Statement. JAMA Oncol. e-Pub 2024. PMID: 38990526.
- Islam S, Gleber-Netto FO, Mulcahy CF, Glaun MDE, Srivastava S, Hunt PJ, Williams MD, Barbon CE, Spiotto M, Zhao W, Adebayo A, Akhter S, Xie T, Debnath KC, Sathishkumar HN, Myers B, Lothumalla S, Yaman I, Burks JK, Gomez J, Rao X, Wang J, Woodman K, Mansour J, Arenkiel B, Osman KL, Haxton C, Lever TE, Hutcheson KA, Amit M. Neural landscape is associated with functional outcomes in irradiated patients with oropharyngeal squamous cell carcinoma. Sci Transl Med 16(758):eabq5585, 2024. e-Pub 2024. PMID: 39083586.
- Jin L, Tang Y, Coole JB, Tan MT, Zhao X, Badaoui H, Robinson JT, Williams MD, Vigneswaran N, Gillenwater AM, Richards-Kortum RR, Veeraraghavan A. DeepDOF-SE: affordable deep-learning microscopy platform for slide-free histology. Nat Commun 15(1):2935, 2024. e-Pub 2024. PMID: 38580633.
- Goldberg H, Jiang X, Fan J, Zhao J, Ning J, Williams MD, Frank S, Moreno A, Gunn B, Ferrarotto R, Esmaeli B. Lacrimal Gland Adenocarcinoma Clinicopathologic Features and Outcomes Compared With Those of Lacrimal Gland Adenoid Cystic Carcinoma. Ophthalmic Plast Reconstr Surg. e-Pub 2024. PMID: 38319188.
- Yaniv D, Seiwert TY, Margalit DN, Williams MD, Barbon CEA, Largo RD, Smith JA, Gross ND. Neoadjuvant chemotherapy for advanced oral cavity cancer. CA Cancer J Clin. e-Pub 2024. PMID: 38329372.
- Coca-Pelaz A, Rodrigo JP, Agaimy A, Williams MD, Saba NF, Nuyts S, Randolph GW, López F, Vander Poorten V, Kowalski LP, Civantos FJ, Zafereo ME, Mäkitie AA, Cohen O, Nixon IJ, Rinaldo A, Ferlito A. Poorly differentiated thyroid carcinomas: conceptual controversy and clinical impact. Virchows Arch. e-Pub 2024. PMID: 38400843.
- Zeng PYF, Prokopec SD, Lai SY, Pinto N, Chan-Seng-Yue MA, Clifton-Bligh R, Williams MD, Howlett CJ, Plantinga P, Cecchini MJ, Lam AK, Siddiqui I, Wang J, Sun RX, Watson JD, Korah R, Carling T, Agrawal N, Cipriani N, Ball D, Nelkin B, Rooper LM, Bishop JA, Garnis C, Berean K, Nicolson NG, Weinberger P, Henderson YC, Lalansingh CM, Tian M, Yamaguchi TN, Livingstone J, Salcedo A, Patel K, Vizeacoumar F, Datti A, Xi L, Nikiforov YE, Smallridge R, Copland JA, Marlow LA, Hyrcza MD, Delbridge L, Sidhu S, Sywak M, Robinson B, Fung K, Ghasemi F, Kwan K, MacNeil SD, Mendez A, Palma DA, Khan MI, Shaikh M, Ruicci KM, Wehrli B, Winquist E, Yoo J, Mymryk JS, Rocco JW, Wheeler D, Scherer S, Giordano TJ, Barrett JW, Faquin WC, Gill AJ, Clayman G, Boutros PC, Nichols AC. The genomic and evolutionary landscapes of anaplastic thyroid carcinoma. Cell Rep 43(3):113826. e-Pub 2024. PMID: 38412093.
- Pezzi TA, Mohamed AS, Sheu T, Blanchard P, Sandulache VC, Lai SY, Cabanillas ME, Williams MD, Pezzi CM, Lu C, Garden AS, Morrison WH, Rosenthal DI, Fuller CD, Gunn GB. Radiation therapy dose is associated with improved survival for unresected anaplastic thyroid carcinoma: Outcomes from the National Cancer Data Base. Cancer, 2024. PMID: 28026871.
- Shaha AR, Silver CE, Angelos P, Nixon IJ, Rodrigo JP, Sanabria A, Poorten VV, Williams MD, Rinaldo A, Ferlito A. The Central Compartment - Center of Controversy, Confusion, and Concern in Management of Differentiated Thyroid Cancer. European Journal of Surgical Oncology, 2024.
- Iyer P, Dadu R, Ferrarotto R, Busaidy NL, Habra MA, Hess KR, Gule-Monroe M, Williams MD, Cabanillas ME. Molecular targeted therapy for the treatment of anaplastic thyroid carcinoma. Thyroid, 2024.
- Valenciaga A, Grubbs EE, Porter K, Wakely PE, Williams MD, Cote GJ, Vasko VV, Saj M, Ringel MD. Reduced Retinoblastoma Protein Expression is Associated With Decreased Patient Survival in Medullary Thyroid Cancer. Thyroid, 2024.
- Naara S, Andrews C, Sikora A, Williams MD, Chambers M, Myers J, Amit M. Oral Pre-malignancy: An Update on Novel Therapeutic Approaches. Current Oncol Reports, 2024.
- Szabo Yamashita T, Shirali AS, Meas S, Sarli V, Clemente-Gutierrez UE, Chiang YJ, Silva-Figueroa A, Vodopivec DM, Williams MD, Fisher SB, Graham PH, Grubbs EG, Lucci A, Busaidy N, Perrier ND. Is there a role for liquid biopsy in the surveillance of parathyroid carcinoma?. Surgery. e-Pub 2023. PMID: 37993289.
- Haddad R, Elisei R, Hoff AO, Liu Z, Pitoia F, Pruneri G, Sadow PM, Soares F, Turk A, Williams MD, Wirth LJ, Cabanillas ME. Diagnosis and Management of Tropomyosin Receptor Kinase Fusion-Positive Thyroid Carcinomas: A Review. JAMA Oncol. e-Pub 2023. PMID: 37289450.
- Lu L, Wang JR, Henderson YC, Bai S, Yang J, Hu M, Shiau CK, Pan TY, Yan Y, Tran TM, Li J, Kieser R, Zhao X, Wang J, Nurieva R, Williams MD, Cabanillas ME, Dadu R, Busaidy N, Zafereo M, Navin N, Lai SY, Gao R. Anaplastic transformation in thyroid cancer revealed by single cell transcriptomics. J Clin Invest. e-Pub 2023. PMID: 37053016.
- Contrera KJ, Shakibai N, Su SY, Gule-Monroe MK, Roberts D, Brahimaj B, Williams MD, Ferrarotto R, Phan J, Gunn B, Raza S, DeMonte F, Hanna EY. Impact of Clinical Factors and Treatments on SMARCB1 (INI-1)-Deficient Sinonasal Carcinoma. Otolaryngol Head Neck Surg. e-Pub 2023. PMID: 36856048.
- Zhao X, Wang JR, Dadu R, Busaidy NL, Xu L, Learned KO, Chasen NN, Vu T, Maniakas A, Eguia AA, Diersing J, Gross ND, Goepfert R, Lai SY, Hofmann MC, Ferrarotto R, Lu C, Gunn GB, Spiotto MT, Subbiah V, Williams MD, Cabanillas ME, Zafereo ME. Surgery After BRAF-Directed Therapy Is Associated with Improved Survival in BRAFV600E Mutant Anaplastic Thyroid Cancer: A Single-Center Retrospective Cohort Study. Thyroid. e-Pub 2023. PMID: 36762947.
- Coole J.B, Brenes D, Mitbander R, Vohra I, Hou H, Kortum A, Tang Y, Maker Y, Schwarz R.A, Carns J, Badaoui H, Williams MD, Vigneswaran N, Gillenwater A, Richards-Kortum, R. Multimodal optical imaging with real-time projection of cancer risk and biopsy guidance maps for early oral cancer diagnosis and treatment. J. Biomed 28(1), 2023.
- Zhang X, Gleber-Netto FO, Wang S, Martins-Chaves RR, Gomez RS, Vigneswaran N, Sarkar A, William WN, Papadimitrakopoulou V, Williams MD, Bell D, Palsgrove D, Bishop J, Heymach JV, Gillenwater AM, Myers JN, Ferrarotto R, Lippman SM, Pickering CR, Xiao G. Deep learning-based pathology image analysis predicts cancer progression risk in patients with oral leukoplakia. Cancer Med. e-Pub 2023. PMID: 36721313.
- Brenes DR, Nipper AJ, Tan MT, Gleber-Netto FO, Schwarz RA, Pickering CR, Williams MD, Vigneswaran N, Gillenwater AM, Sikora AG, Richards-Kortum RR. Mildly dysplastic oral lesions with optically-detectable abnormalities share genetic similarities with severely dysplastic lesions. Oral Oncol 135:106232, 2022. e-Pub 2022. PMID: 36335817.
- Contrera KJ, Gule-Monroe M, Hu MI, Cabanillas M, Busaidy N, Dadu R, Waguespack SG, Wang JR, Maniakas A, Lai SY, Diersing J, Kwon M, Grubbs EG, Subbiah V, Williams MD, Zafereo ME. Neoadjuvant Selective RET Inhibitor for Medullary Thyroid Cancer: A Case Series. Thyroid. e-Pub 2022. PMID: 36503246.
- Chen YH, Cabanillas M, Sperling J, Xu L, Goswami M, Maniakas A, Williams MD, Lai SY, Busaidy N, Dadu R, Zafereo ME, Wang JR. Prior thyroid and non-thyroid cancer history do not significantly alter overall survival in patients diagnosed with anaplastic thyroid carcinoma. Thyroid. e-Pub 2022. PMID: 36511380.
- Zhao J, Papp AM, Williams MD, Debnam JM, Esmaeli B. Multifocal recurrence of pleomorphic adenoma of the lacrimal gland. Am J Ophthalmol Case Rep 27:101600, 2022. e-Pub 2022. PMID: 35677816.
- Sajisevi M, Caulley L, Eskander A, Du Y, Auh E, Karabachev A, Callas P, Conradle W, Martin L, Pasternak J, Golbon B, Rolighed L, Ahmed A, Badhey A, Cheung A, Corsten M, Former D, Liu J, Mavedatnia D, Meltzer C, Noel J, Patel V, Sharma A, Tang A, Tsao G, Venkatramani M, Williams MD, Wrenn S, Zafereo M, Stack B, Randolph G, Davies L. Evaluating the Rising Incidence of Thyroid Cancer and Thyroid Nodule Detection Modes. JAMA Otolaryngology-Head & Neck Surgery, 2022.
- Vander Poorten V, Goedseels N, Triantafyllou A, Sanabria A, Clement PM, Cohen O, Golusinski P, Guntinas-Lichius O, Piazza C, Randolph GW, Rinaldo A, Ronen O, Cabanillas ME, Shaha AR, Teng Y, Tufano RP, Williams MD, Zafereo M, Ferlito A. Effectiveness of core needle biopsy in the diagnosis of thyroid lymphoma and anaplastic thyroid carcinoma: A systematic review and meta-analysis. Front Endocrinol (Lausanne) 13:971249, 2022. e-Pub 2022. PMID: 36204100.
- Ho J, Mattei J, Tetzlaff M, Williams MD, Davies MA, Diab A, Oliva ICG, McQuade J, Patel SP, Tawbi H, Wong MK, Fisher SB, Hanna E, Keung EZ, Ross M, Weiser R, Su SY, Frumovitz M, Meyer LA, Jazaeri A, Pettaway CA, Guadagnolo BA, Bishop AJ, Mitra D, Farooqi A, Bassett R, Faria S, Nagarajan P, Amaria RN. Neoadjuvant checkpoint inhibitor immunotherapy for resectable mucosal melanoma. Front Oncol 12:1001150, 2022. e-Pub 2022. PMID: 36324592.
- Fernandez Branson C, Williams MD, Chan TM, Graber ML, Lane KP, Grieser S, Landis-Lewis Z, Cooke J, Upadhyay DK, Mondoux S, Singh H, Zwaan L, Friedman C, Olson APJ. Improving diagnostic performance through feedback: the Diagnosis Learning Cycle. BMJ Qual Saf 30(12):1002-1009, 2021. e-Pub 2021. PMID: 34417335.
- Boucai L, Seshan V, Williams MD, Knauf JA, Saqcena M, Ghossein RA, Fagin JA. Characterization of Subtypes of BRAF-Mutant Papillary Thyroid Cancer Defined by Their Thyroid Differentiation Score. J Clin Endocrinol Metab. e-Pub 2021. PMID: 34897468.
- Caulley L, Eskander A, Yang W, Auh E, Cairncross L, Cho NL, Golbon B, Iyer S, Liu JC, Lee PJ, Lindeman B, Meltzer C, Molin N, Moore A, Noel J, Nozolino H, Pasternak J, Price B, Ramsay T, Rolighed L, Sajisevi M, Sharma A, Sinclair C, Sorensen M, Tae K, Tang AL, Tsao G, Williams M, Wrenn S, Xing MH, Zafereo M, Stack BC, Randolph G, Davies L. Trends in Diagnosis of Noninvasive Follicular Thyroid Neoplasm With Papillarylike Nuclear Features and Total Thyroidectomies for Patients With Papillary Thyroid Neoplasms. JAMA Otolaryngol Head Neck Surg. e-Pub 2021. PMID: 34817546.
- Bagheri-Yarmand R, Busaidy NL, McBeath E, Danysh BP, Evans KW, Moss TJ, Akcakanat A, Ng PKS, Knippler CM, Golden JA, Williams MD, Multani AS, Cabanillas ME, Shaw KR, Meric-Bernstam F, Shah MH, Ringel MD, Hofmann MC. RAC1 Alterations Induce Acquired Dabrafenib Resistance in Association with Anaplastic Transformation in a Papillary Thyroid Cancer Patient. Cancers (Basel) 13(19), 2021. e-Pub 2021. PMID: 34638434.
- Williams MD. Preoperative Molecular Testing of Thyroid Nodules: Current Concepts. Neuroimaging Clin N Am 31(3):301-312, 2021. PMID: 34243865.
- Liu Z, Williams MD, Stewart J, Glisson BS, Fuller C, Roy-Chowdhuri S. Evaluation of programmed death ligand 1 expression in cytology to determine eligibility for immune checkpoint inhibitor therapy in patients with head and neck squamous cell carcinoma. Cancer Cytopathol. e-Pub 2021. PMID: 34375025.
- Henderson YC, Mohamed ASR, Maniakas A, Chen Y, Powell RT, Peng S, Cardenas M, Williams MD, Bell D, Zafereo ME, Wang RJ, Scherer SE, Wheeler DA, Cabanillas ME, Hofmann MC, Johnson FM, Stephan CC, Sandulache V, Lai SY. A High-Throughput Approach to Identify Effective Systemic Agents for the Treatment of Anaplastic Thyroid Carcinoma. J Clin Endocrinol Metab. e-Pub 2021. PMID: 34120183.
- Maniakas A, Henderson YC, Hei H, Peng S, Chen Y, Jiang Y, Ji S, Cardenas M, Chiu Y, Bell D, Williams MD, Hofmann MC, Scherer SE, Wheeler DA, Busaidy NL, Dadu R, Wang JR, Cabanillas ME, Zafereo M, Johnson FM, Lai SY. Novel anaplastic thyroid cancer PDXs and cell lines: Expanding preclinical models of genetic diversity. J Clin Endocrinol Metab. e-Pub 2021. PMID: 34147031.
- Franchi A, Thompson LDR, Hernandez-Prera JC, Agaimy A, Williams MD, Mikkelsen LH, Bishop JA, Willems SM, Hellquist H, Ferlito A. Emerging Entities and New Diagnostic Markers for Head and Neck Soft Tissue and Bone Tumors. Adv Anat Pathol. e-Pub 2021. PMID: 33559990.
- Qin YU, Wang JR, Wang Y, Iyer PC, Cote G, Busaidy N, Dadu R, Zafereo M, Williams MD, Ferrarotto R, Gunn B, Wei P, Patel K, Hofmann MC, Cabanillas M. Clinical Utility of Circulating Cell-free DNA Mutations in Anaplastic Thyroid Carcinoma. Thyroid. e-Pub 2021. PMID: 33599171.
- Jozaghi Y, Zafereo M, Williams MD, Gule-Monroe MK, Wang J, Grubbs EG, Vaporciyan A, Hu MI, Busaidy N, Dadu R, Waguespack SG, Subbiah V, Cabanillas M. Neoadjuvant selpercatinib for advanced medullary thyroid cancer. Head Neck 43(1):E7-E12, 2021. e-Pub 2020. PMID: 33169506.
- Williams MD, Ma J, Grubbs EG, Gagel RF, Bagheri-Yarmand R. ATF4 loss of heterozygosity is associated with poor overall survival in medullary thyroid carcinoma. Am J Cancer Res 11(6):3227-3239, 2021. e-Pub 2021. PMID: 34249457.
- Del Valle Estopinal M, Middleton LP, Esmaeli B, Patel KP, Nowroozizadeh S, Williams MD. Primary Signet Ring Cell/Histiocytoid Carcinoma of the Eyelid: Clinicopathologic Analysis with Evaluation of the E-Cadherin/β-Catenin Complex and Associated Genetic Alterations. Case Rep Pathol 2021:6628150, 2021. e-Pub 2021. PMID: 34804623.
- Qin Y, Bollin K, de Macedo MP, Carapeto F, Kim KB, Roszik J, Wani KM, Reuben A, Reddy ST, Williams MD, Tetzlaff MT, Wang WL, Gombos DS, Esmaeli B, Lazar AJ, Hwu P, Patel SP. Immune profiling of uveal melanoma identifies a potential signature associated with response to immunotherapy. J Immunother Cancer 8(2), 2020. PMID: 33203661.
- Maniakas A, Dadu R, Busaidy NL, Wang JR, Ferrarotto R, Lu C, Williams MD, Gunn GB, Hofmann MC, Cote G, Sperling J, Gross ND, Sturgis EM, Goepfert RP, Lai SY, Cabanillas ME, Zafereo M. Evaluation of Overall Survival in Patients With Anaplastic Thyroid Carcinoma, 2000-2019. JAMA Oncol 6(9):1397-1404, 2020. PMID: 32761153.
- Yang EC, Brenes DR, Vohra IS, Schwarz RA, Williams MD, Vigneswaran N, Gillenwater AM, Richards-Kortum RR. Algorithm to quantify nuclear features and confidence intervals for classification of oral neoplasia from high-resolution optical images. J Med Imaging (Bellingham) 7(5):054502, 2020. e-Pub 2020. PMID: 32999894.
- Choi KY, Amit M, Tam S, Bell D, Phan J, Garden AS, Williams MD, Ferrarotto R, El-Naggar AK, Raza SM, DeMonte F, Kupferman ME, Hanna EY, Su SY. Clinical Implication of Diagnostic and Histopathologic Discrepancies in Sinonasal Malignancies. Laryngoscope. e-Pub 2020. PMID: 32946597.
- Lee DY, Brayer KJ, Mitani Y, Burns EA, Rao PH, Bell D, Williams MD, Ferrarotto R, Pytynia KB, El-Naggar AK, Ness SA. Oncogenic Orphan Nuclear Receptor NR4A3 Interacts and Cooperates with MYB in Acinic Cell Carcinoma. Cancers (Basel) 12(9), 2020. e-Pub 2020. PMID: 32867110.
- Williams MD, DeLellis RA, Erickson LA, Gupta R, Johnson SJ, Kameyama K, Natu S, Ng T, Perren A, Perrier ND, Seethala RR, Gill AJ. Pathology data set for reporting parathyroid carcinoma and atypical parathyroid neoplasm: recommendations from the International Collaboration on Cancer Reporting. Hum Pathol. e-Pub 2020. PMID: 32687943.
- Zafereo M, McIver B, Vargas-Salas S, Domínguez JM, Steward DL, Holsinger FC, Kandil E, Williams M, Cruz F, Loyola S, Solar A, Roa JC, León A, Droppelman N, Lobos M, Arias T, Kong CS, Busaidy N, Grubbs EG, Graham P, Stewart J, Tang A, Wang J, Orloff L, Henríquez M, Lagos M, Osorio M, Schachter D, Franco C, Medina F, Wohllk N, Diaz RE, Veliz J, Horvath E, Tala H, Pineda P, Arroyo P, Vasquez F, Traipe E, Marín L, Miranda G, Bruce E, Bracamonte M, Mena N, González HE. A Thyroid Genetic Classifier Correctly Predicts Benign Nodules With Indeterminate Cytology: Two-Independent Multicenter, Prospective Validation Trials. Thyroid 30(5):704-712, 2020. e-Pub 2020. PMID: 31910118.
- Chari NS, Ivan C, Le X, Li J, Mijiti A, Patel AA, Osman AA, Peterson CB, Williams MD, Pickering CR, Caulin C, Myers JN, Calin GA, Lai SY. Disruption of TP63-miR-27a* feedback loop by mutant TP53 in head and neck cancer. J Natl Cancer Inst 112(3):266-277, 2020. e-Pub 2019. PMID: 31124563.
- Yang EC, Vohra IS, Badaoui H, Schwarz RA, Cherry KD, Jacob J, Rodriguez J, Williams MD, Vigneswaran N, Gillenwater AM, Richards-Kortum RR. Prospective evaluation of oral premalignant lesions using a multimodal imaging system: a pilot study. Head Neck 42(2):171-179, 2020. e-Pub 2019. PMID: 31621979.
- Liang L, Williams MD, Bell D. Expression of PTEN, Androgen Receptor, HER2/neu, Cytokeratin 5/6, Estrogen Receptor-Beta, HMGA2, and PLAG1 in Salivary Duct Carcinoma. Head Neck Pathol 13(4):529-534, 2019. e-Pub 2018. PMID: 30390196.
- Silva-Figueroa AM, Bassett R, Christakis I, Moreno P, Clarke CN, Busaidy NL, Grubbs EG, Lee JE, Perrier ND, Williams MD. Using a Novel Diagnostic Nomogram to Differentiate Malignant from Benign Parathyroid Neoplasms. Endocr Pathol 30(4):285-296, 2019. e-Pub 2019. PMID: 31734935.
- Cherry KD, Schwarz RA, Yang EC, Vohra IS, Badaoui H, Williams MD, Vigneswaran N, Gillenwater AM, Richards-Kortum R. Autofluorescence Imaging to Monitor the Progression of Oral Potentially Malignant Disorders. Cancer Prev Res (Phila) 12(11):791-800, 2019. e-Pub 2019. PMID: 31451520.
- Asare EA, Silva-Figueroa A, Hess KR, Busaidy N, Graham PH, Grubbs EG, Lee JE, Williams MD, Perrier ND. Risk of Distant Metastasis in Parathyroid Carcinoma and Its Effect on Survival: A Retrospective Review from a High-Volume Center. Ann Surg Oncol 26(11):3593-3599, 2019. e-Pub 2019. PMID: 31111352.
- Wang JR, Zafereo ME, Dadu R, Ferrarotto R, Busaidy NL, Lu C, Ahmed S, Gule-Monroe MK, Williams MD, Sturgis EM, Goepfert RP, Gross ND, Lai SY, Gunn GB, Phan J, Rosenthal DI, Fuller CD, Morrison WH, Iyer P, Cabanillas ME. Complete Surgical Resection Following Neoadjuvant Dabrafenib Plus Trametinib in BRAFV600E-Mutated Anaplastic Thyroid Carcinoma. Thyroid 29(8):1036-1043, 2019. PMID: 31319771.
- Kutahyalioglu M, Nguyen HT, Kwatampora L, Clarke C, Silva A, Ibrahim E, Waguespack SG, Cabanillas ME, Jimenez C, Hu MI, Sherman SI, Kopetz S, Broaddus R, Dadu R, Wanland K, Williams M, Zafereo M, Perrier N, Busaidy NL. Genetic profiling as a clinical tool in advanced parathyroid carcinoma. J Cancer Res Clin Oncol 145(8):1977-1986, 2019. e-Pub 2019. PMID: 31309300.
- Acharya RP, Won AM, Moon BS, Flint JH, Roubaud MS, Williams MD, Hessel AC, Murphy WA, Chambers MS, Gagel RF. Tumor-induced hypophosphatemic osteomalacia caused by a mesenchymal tumor of the mandible managed by a segmental mandibulectomy and microvascular reconstruction with a free fibula flap. Head Neck 41(6):E93-E98, 2019. e-Pub 2019. PMID: 30859653.
- Williams MD, Franchi A, Helliwell T, Müller S, Thompson LDR. Data Set for Reporting of Mucosal Melanomas of the Head and Neck: Explanations and Recommendations of the Guidelines From the International Collaboration on Cancer Reporting. Arch Pathol Lab Med 143(5):603-609, 2019. e-Pub 2018. PMID: 30500297.
- Bullock MJ, Beitler JJ, Carlson DL, Fonseca I, Hunt JL, Katabi N, Sloan P, Taylor SM, Williams MD, Thompson LDR. Data Set for the Reporting of Nodal Excisions and Neck Dissection Specimens for Head and Neck Tumors: Explanations and Recommendations of the Guidelines From the International Collaboration on Cancer Reporting. Arch Pathol Lab Med 143(4):452-462, 2019. e-Pub 2018. PMID: 30500291.
- Genutis LK, Tomsic J, Bundschuh RA, Brock PL, Williams MD, Roychowdhury S, Reeser JW, Frankel WL, Alsomali M, Routbort MJ, Broaddus RR, Wakely PE, Phay JE, Walker CJ, de la Chapelle A. Microsatellite Instability Occurs in a Subset of Follicular Thyroid Cancers. Thyroid 29(4):523-529, 2019. e-Pub 2019. PMID: 30747051.
- Guo M, Khanna A, Wang J, Williams MD, Kalhor N, Gong Y, Xu L, Sturgis EM, Staerkel G. Incorporation of Cervista Human Papillomavirus 16/18 Assay Into Algorithms for Classifying Human Papillomavirus Status in Formalin-Fixed, Paraffin-Embedded Head and Neck Squamous Carcinoma Specimens. Arch Pathol Lab Med 143(3):356-361, 2019. e-Pub 2018. PMID: 30221979.
- Haddad RI, Massarelli E, Lee JJ, Lin HY, Hutcheson K, Lewis J, Garden AS, Blumenschein GR, William WN, Pharaon RR, Tishler RB, Glisson BS, Pickering C, Gold KA, Johnson FM, Rabinowits G, Ginsberg LE, Williams MD, Myers J, Kies MS, Papadimitrakopoulou V. Weekly paclitaxel, carboplatin, cetuximab, and cetuximab, docetaxel, cisplatin, and fluorouracil, followed by local therapy in previously untreated, locally advanced head and neck squamous cell carcinoma. Ann Oncol 30(3):471-477, 2019. PMID: 30596812.
- Ye W, Hannigan B, Zalles S, Mehrotra M, Barkoh BA, Williams MD, Cabanillas ME, Edeiken-Monroe B, Hu P, Duose D, Wistuba II, Medeiros LJ, Stewart J, Luthra R, Roy-Chowdhuri S. Centrifuged supernatants from FNA provide a liquid biopsy option for clinical next-generation sequencing of thyroid nodules. Cancer Cytopathol 127(3):146-160, 2019. e-Pub 2019. PMID: 30620446.
- Gale N, Hille J, Jordan RC, Nadal A, Williams MD. Regarding Laryngeal precursor lesions: Interrater and intrarater reliability of histopathological assessment. Laryngoscope 129(3):E91-E92, 2019. e-Pub 2019. PMID: 30637764.
- Clarke CN, Katsonis P, Hsu TK, Koire AM, Silva-Figueroa A, Christakis I, Williams MD, Kutahyalioglu M, Kwatampora L, Xi Y, Lee JE, Koptez ES, Busaidy NL, Perrier ND, Lichtarge O. Comprehensive Genomic Characterization of Parathyroid Cancer Identifies Novel Candidate Driver Mutations and Core Pathways. J Endocr Soc 3(3):544-559, 2019. e-Pub 2018. PMID: 30788456.
- Thomas Robbins K, Triantafyllou A, Suárez C, López F, Hunt JL, Strojan P, Williams MD, Braakhuis BJM, de Bree R, Hinni ML, Kowalski LP, Rinaldo A, Rodrigo JP, Vander Poorten V, Nixon IJ, Takes RP, Silver CE, Ferlito A. Surgical margins in head and neck cancer: Intra- and postoperative considerations. Auris Nasus Larynx 46(1):10-17, 2019. e-Pub 2018. PMID: 30172560.
- Yang EC, Vohra IS, Badaoui H, Schwarz RA, Cherry KD, Quang T, Jacob J, Lang A, Bass N, Rodriguez J, Williams MD, Vigneswaran N, Gillenwater AM, Richards-Kortum RR. Development of an integrated multimodal optical imaging system with real-time image analysis for the evaluation of oral premalignant lesions. J Biomed Opt 24(2):1-10, 2019. PMID: 30793567.
- Nikiforova MN, Nikitski AV, Panebianco F, Kaya C, Yip L, Williams MD, Chiosea SI, Seethala RR, Roy S, Condello V, Santana-Santos L, Wald AI, Carty SE, Ferris RL, El-Naggar AK, Nikiforov YE. GLIS Rearrangement is a Genomic Hallmark of Hyalinizing Trabecular Tumor of the Thyroid Gland. Thyroid 29(2):161-173, 2019. PMID: 30648929.
- Fisher SB, Cote GJ, Bui-Griffith JH, Lu W, Tang X, Hai T, Fisher KE, Williams MD, Wistuba II, Waguespack SG, Dorman CM, Ludwig MS, Graham PH, Perrier ND, Lee JE, Grubbs EG. Genetic characterization of medullary thyroid cancer in childhood survivors of the Chernobyl accident. Surgery 165(1):58-63, 2019. e-Pub 2018. PMID: 30392857.
- Smith AL, Williams MD, Stewart J, Wang WL, Krishnamurthy S, Cabanillas ME, Roy-Chowdhuri S. Utility of the BRAF p.V600E immunoperoxidase stain in FNA direct smears and cell block preparations from patients with thyroid carcinoma. Cancer Cytopathol 126(6):406-413, 2018. e-Pub 2018. PMID: 29579361.
- Henderson YC, Ahn SH, Ryu J, Chen Y, Williams MD, El-Naggar AK, Gagea M, Schweppe RE, Haugen BR, Lai SY, Clayman GL. Development and Characterization of Six New Human Papillary Thyroid Carcinoma Cell Lines. J Clin Endocrinol Metab 100(2):jc20142624, 2015. e-Pub 2014. PMID: 25427145.
- Shawa H, Elsayes KM, Javadi S, Morani A, Williams MD, Lee JE, Waguespack SG, Busaidy NL, Vassilopoulou-Sellin R, Jimenez C, Habra MA. Adrenal Ganglioneuroma: Features and outcomes of 27 cases at a referral cancer center. Clin Endocrinol (Oxf) 80(3):342-7, 2014. e-Pub 2013. PMID: 24033606.
- Ahn SH, Henderson YC, Williams MD, Lai SY, Clayman GL. Detection of Thyroid Cancer Stem Cells in Papillary Thyroid Carcinoma. J Clin Endocrinol Metab 99(2):536-44, 2014. e-Pub 2013. PMID: 24302752.
- Lewis JS, Westra WH, Thompson LD, Barnes L, Cardesa A, Hunt JL, Williams MD, Slootweg PJ, Triantafyllou A, Woolgar JA, Devaney KO, Rinaldo A, Ferlito A. The Sinonasal Tract: Another Potential "Hot Spot" for Carcinomas with Transcriptionally-Active Human Papillomavirus. Head Neck Pathol 8(3):241-9, 2014. e-Pub 2013. PMID: 24338611.
- Sandulache VC, Chen Y, Lee J, Rubinstein A, Ramirez MS, Skinner HD, Walker CM, Williams MD, Tailor R, Court LE, Bankson JA, Lai SY. Evaluation of hyperpolarized [1-¹³C]-pyruvate by magnetic resonance to detect ionizing radiation effects in real time. PLoS One 9(1):e87031, 2014. e-Pub 2014. PMID: 24475215.
- Beadle BM, William WN, McLemore MS, Sturgis EM, Williams MD. p16 Expression in cutaneous squamous carcinomas with neck metastases: A potential pitfall in identifying unknown primaries of the head and neck. Head Neck 35(11):1527-33, 2013. e-Pub 2012. PMID: 23108906.
- Kim KB, Cabanillas ME, Lazar AJ, Williams MD, Sanders DL, Ilagan JL, Nolop K, Lee RJ, Sherman SI. Clinical Responses to Vemurafenib in Patients with Metastatic Papillary Thyroid Cancer Harboring V600E BRAF mutation. Thyroid 23(10):1277-83, 2013. e-Pub 2013. PMID: 23489023.
- Peng S, Creighton CJ, Zhang Y, Sen B, Mazumdar T, Myers JN, Lai SY, Woolfson A, Lorenzi MV, Bell D, Williams MD, Johnson FM. Tumor grafts derived from patients with head and neck squamous carcinoma authentically maintain the molecular and histologic characteristics of human cancers. J Transl Med 11(1):198, 2013. e-Pub 2013. PMID: 23981300.
- Woolgar JA, Triantafyllou A, Lewis JS, Hunt J, Williams MD, Takes RP, Thompson LD, Slootweg PJ, Devaney KO, Ferlito A. Prognostic biological features in neck dissection specimens. Eur Arch Otorhinolaryngol 270(5):1581-1592, 2013. e-Pub 2012. PMID: 22983222.
- Rosbach KJ, Williams MD, Gillenwater AM, Richards-Kortum RR. Optical molecular imaging of multiple biomarkers of epithelial neoplasia: epidermal growth factor receptor expression and metabolic activity in oral mucosa. Transl Oncol 5(3):160-71, 2012. e-Pub 2012. PMID: 22741035.
- Thariat J, Ang KK, Allen PK, Ahamad A, Williams MD, Myers JN, El-Naggar AK, Ginsberg LE, Rosenthal DI, Glisson BS, Morrison WH, Weber RS, Garden AS. Prediction of neck dissection requirement after definitive radiotherapy for head-and-neck squamous cell carcinoma. Int J Radiat Oncol Biol Phys 82(3):e367-74, 2012. PMID: 22284033.
- Williams MD, Zhang L, Elliott DD, Perrier ND, Lozano G, Clayman GL, El-Naggar AK. Differential Gene Expression Profiling of Aggressive and Nonaggressive Follicular Carcinomas. Hum Pathol 42(9):1213-20, 2011. e-Pub 2011. PMID: 21420716.
- Moeller BJ, Yordy JS, Williams MD, Giri U, Raju U, Molkentine DP, Byers LA, Heymach JV, Story MD, Lee JJ, Sturgis EM, Weber RS, Garden AS, Ang KK, Schwartz DL. DNA Repair Biomarker Profiling of Head and Neck Cancer: Ku80 Expression Predicts Locoregional Failure and Death Following Radiotherapy. Clin Cancer Res 17(7):2035-43, 2011. e-Pub 2011. PMID: 21349997.
- Frederick MJ, VanMeter AJ, Gadhikar MA, Henderson YC, Yao H, Pickering CC, Williams MD, El-Naggar AK, Sandulache V, Tarco E, Myers JN, Clayman GL, Liotta LA, Petricoin EF, Calvert VS, Fodale V, Wang J, Weber RS. Phosphoproteomic Analysis of Signaling Pathways in Head and Neck Squamous Cell Carcinoma Patient Samples. Am J Pathol 178(2):548-71, 2011. PMID: 21281788.
- Sen B, Peng S, Saigal B, Williams MD, Johnson FM. Distinct Interactions Between c-Src and c-Met in Mediating Resistance to c-Src Inhibition in Head and Neck Cancer. Clin Cancer Res 17(3):514-24, 2011. e-Pub 2010. PMID: 21106725.
- Kupferman ME, de la Garza GO, Santillan AA, Williams MD, Varghese BT, Huh W, Roberts D, Weber RS. Outcomes of Pediatric Patients with Malignancies of the Major Salivary Glands. Ann Surg Oncol 17(12):3301-7, 2010. e-Pub 2010. PMID: 20585877.
- Moeller BJ, Rana V, Cannon BA, Williams MD, Sturgis EM, Ginsberg LE, Macapinlac HA, Lee JJ, Ang KK, Chao KS, Chronowski GM, Frank SJ, Morrison WH, Rosenthal DI, Weber RS, Garden AS, Lippman SM, Schwartz DL. Prospective Imaging Assessment of Mortality Risk After Head-and-Neck Radiotherapy. Int J Radiat Oncol Biol Phys 78(3):667-74, 2010. e-Pub 2010. PMID: 20171802.
- Williams MD, Al-Zubidi N, Debnam JM, Shinder R, DeMonte F, Esmaeli B. Bone Invasion by Adenoid Cystic Carcinoma of the Lacrimal Gland: Preoperative Imaging Assessment and Surgical Considerations. Ophthal Plast Reconstr Surg 26(6):403-8, 2010. PMID: 20924298.
- Roblyer D, Kurachi C, Stepanek V, Schwarz RA, Williams MD, El-Naggar AK, Lee JJ, Gillenwater AM, Richards-Kortum R. Comparison of Multispectral Widefield Optical Imaging Modalities to Maximize Image Contrast for Objective Discrimination of Oral Neoplasia. J Biomed Opt 15(6):066017, 2010. PMID: 21198191.
- Williams MD, Esmaeli B, Soheili A, Simantov R, Gombos DS, Bedikian AY, Hwu P. GPNMB Expression in Uveal Melanoma: A Potential for Targeted Therapy. Melanoma Res 20(3):184-90, 2010. PMID: 20375921.
- Cabanillas ME, Waguespack SG, Bronstein Y, Williams MD, Feng L, Hernandez M, Lopez A, Sherman SI, Busaidy NL. Treatment with Tyrosine Kinase Inhibitors for Patients with Differentiated Thyroid Cancer: The M. D. Anderson Experience. J Clin Endocrinol Metab 95(6):2588-95, 2010. e-Pub 2010. PMID: 20392874.
- Moreno MA, Roberts DB, Kupferman ME, DeMonte F, El-Naggar AK, Williams M, Rosenthal DS, Hanna EY. Mucosal Melanoma of the Nose and Paranasal Sinuses, a Contemporary Experience from the M. D. Anderson Cancer Center. Cancer 116(9):2215-23, 2010. PMID: 20198705.
- Weigum SE, Floriano PN, Redding SW, Yeh CK, Westbrook SD, McGuff HS, Lin A, Miller FR, Villarreal F, Rowan SD, Vigneswaran N, Williams MD, McDevitt JT. Nano-bio-chip Sensor Platform for Examination of Oral Exfoliative Cytology. Cancer Prev Res (Phila) 3(4):518-28, 2010. e-Pub 2010. PMID: 20332305.
- Williams MD, Roberts DB, Kies MS, Mao L, Weber RS, El-Naggar AK. Genetic and Expression Analysis of HER-2 and EGFR Genes in Salivary Duct Carcinoma: Empirical and Therapeutic Significance. Clin Cancer Res 16(8):2266-74, 2010. e-Pub 2010. PMID: 20371674.
- Moskovic DJ, Smolarz JR, Stanley D, Jimenez C, Williams MD, Hanna EY, Kupferman ME. Malignant Head and Neck Paragangliomas: Is There an Optimal Treatment Strategy?. Head Neck Oncol 2:23, 2010. e-Pub 2010. PMID: 20863367.
- Schwarz RA, Gao W, Stepanek VM, Le TT, Bhattar VS, Williams MD, Wu JK, Vigneswaran N, Adler-Storthz K, Gillenwater AM, Richards-Kortum R. Prospective Evaluation of a Portable Depth-sensitive Optical Spectroscopy Device to Identify Oral Neoplasia. Biomed Opt Express 2(1):89-99, 2010. e-Pub 2010. PMID: 21326639.
- Williams MD, Suliburk JW, Staerkel GA, Busaidy NL, Clayman GL, Evans DB, Perrier ND. Clinical Significance of Distinguishing between Follicular Lesion and Follicular Neoplasm in Thyroid Fine-needle Aspiration Biopsy. Ann Surg Oncol 16(11):3146-53, 2009. PMID: 19727961.
- Roblyer D, Kurachi C, Stepanek V, Williams MD, El-Naggar AK, Lee JJ, Gillenwater AM, Richards-Kortum R. Objective Detection and Delineation of Oral Neoplasia Using Autofluorescence Imaging. Cancer Prev Res (Phila) 2(5):423-31, 2009. e-Pub 2009. PMID: 19401530.
- Waguespack SG, Sherman SI, Williams MD, Clayman GL, Herzog CE. The Successful Use of Sorafenib to Treat Pediatric Papillary Thyroid Carcinoma. Thyroid 19(4):407-12, 2009. PMID: 19355831.
- Cordes B, Williams MD, Tirado Y, Bell D, Rosenthal DI, Al-Dhahri SF, Hanna EY, El-Naggar AK. Molecular and Phenotypic Analysis of Poorly Differentiated Sinonasal Neoplasm's: An Integrated Approach for Early Diagnosis and Classification. Hum Pathol 40(3):283-92, 2009. e-Pub 2009. PMID: 19150107.
- Henderson YC, Shellenberger TD, Williams MD, El-Naggar AK, Fredrick MJ, Cieply KM, Clayman GL. High Rate of BRAF and RET/PTC Dual Mutations Associated with Recurrent Papillary Thyroid Carcinoma. Clin Cancer Res 15(2):485-91, 2009. PMID: 19147753.
- Nitin N, Rosbach KJ, El-Naggar A, Williams MD, Gillenwater A, Richards-Kortum RR. Optical Molecular Imaging of Epidermal Growth Factor Receptor Expression to Improve Detection of Oral Neoplasia. Neoplasia 11(6):542-51, 2009.
- Mandal M, Myers JN, Lippman SM, Johnson FM, Williams MD, Rayala S, Ohshiro K, Rosenthal DI, Weber RS, Gallick GE, El-Naggar AK. Epithelial to Mesenchymal Transition in Head and Neck Squamous Carcinoma: Association of Src Activation with E-cadherin Down-regulation, Vimentin Expression, and Aggressive Tumor. Cancer 112(9):2088-2100, 2008. PMID: 18327819.
- Lee ES, Issa JP, Roberts DB, Williams MD, Weber RS, Kies MS, El-Naggar AK. Quantitative Promoter Hypermethylation Analysis of Cancer-related Genes in Salivary Gland Carcinomas: Comparison with Methylation-specific PCR Technique and Clinical Significance. Clin Cancer Res 14(9):2664-2672, 2008. PMID: 18451230.
- Elliott DD, Sherman SI, Busaidy NL, Williams MD, Santarpia L, Clayman GL, El-Naggar AK. Growth Factor Receptors Expression in Anaplastic Thyroid Carcinoma: Potential Markers for Therapeutic Stratification. Hum Pathol 39(1):15-20, 2008. e-Pub 2007. PMID: 17949783.
- Tirado Y, Williams MD, Hanna EY, Kaye FJ, Batsakis JG, El-Naggar AK. CRTC1/MAML2 Fusion Transcript in High Grade Mucoepidermoid Carcinomas of Salivary and Thyroid Glands and Warthin's Tumors: Implications for Histogenesis and Biologic Behavior. Genes Chromosomes Cancer 46(7):708-15, 2007. PMID: 17437281.
- Williams MD, Chakravarti N, Kies MS, Maruya S, Myers JN, Haviland JC, Weber RS, Lotan R, El-Naggar AK. Implications of Methylation Patterns of Cancer Genes in Salivary Gland Tumors. Clin Cancer Res 12(24):7353-7358, 2006. PMID: 17189407.
- Cabanillas M, Dadu R, Ferrarotto R, Gule-Monroe M, Liu S, Fellman B, Williams MD, Zafereo M, Wang J, Lu C, Ning M, McKinley B, Woodman S, Duose D, Gunn G, Busaidy N. Anti-PD-L1 plus targeted therapy in Anaplastic Thyroid Carcinoma. Jama Oncol.
- Williams MD, Liu Z, Rossi E, Agarwal S, Ryska A, Al Ghuzlan A, Chiosea S, Cipriani N, Erkilic S, Fridman M, Jang J, Harahap A, Jung C, Kakudo K, Khali M, Khanafshar E, Kumarasinghe P, Nguyen T, Ocal I, Prasad M, Pustaszeri M, Sadow P, Seethala R, Tallini G, Vuong H, Yegen G, Livolsi V, Nikiforov Y. Seven years of non-invasive follicular thyroid neoplasm with papillary-like nuclei (NIFTP): Rate of acceptance and variation of diagnostic approaches across different continents. J Clin Endocrinol Metab.
Invited Articles
- Lowenstein LM, Basourakos SP, Williams MD, Troncoso P, Gregg JR, Thompson TC, Kim J. Active surveillance for prostate and thyroid cancers: evolution in clinical paradigms and lessons learned. Nat Rev Clin Oncol 16(3):168-184, 2019. PMID: 30413793.
- Thereasa A. Rich, MS, CGC, Michelle D. Williams MD. Paragangliomas Arising in the Head and Neck: A Morphologic review and genetic update Reference. Surgical Pathology Clinics 7(4):543-557, 2014.
- Woodman SE, Williams MD, Esmaeli B. Uveal Melanoma: Molecular Basis and Potential Treatment Targets. US Ophthalmic Review 4(2):131-5, 2011.
- Williams MD. Integration of Biomarkers Including Molecular Targeted Therapies in Head and Neck Cancer. Head Neck Pathol 4(1):62-9, 2010. e-Pub 2010. PMID: 20237991.
- Grubbs EG, Rich TA, Li G, Sturgis EM, Younes MN, Myers JN, Edeiken-Monroe B, Fornage BD, Monroe DP, Staerkel GA, Williams MD, Waguespack SG, Hu MI, Cote G, Gagel RF, Cohen J, Weber RS, Anaya DA, Holsinger FC, Perrier ND, Clayman GL, Evans DB. Recent Advances in Thyroid Cancer. Curr Probl Surg 45(3):156-250, 2008. PMID: 18346477.
Abstracts
- Hamidi S, Dadu R, Busaidy N, Ferrarotto R, Gule-Monroe M, Liu S, Fellman B, Williams M, Zafereo M, Wang R, Lu C, Ning M, McKinley B, Woodman S, Duose D, Cabaniilas M, Gunn G. Cobimetinib plus atezolizumab for RAS and NF1/2-mutated poorly differentiated thyroid carcinoma. J Clin Oncol 42(16), 2024.
- Salem A, Chen M, McQuade J, Amaria R, Swanson D, Williams MD, Farooqi A, Bishop A, Hanna E, Guadagnolo A, Su S, Mitra D. Sinonasal Melanoma Outcomes after Neoadjuvant Immunotherapy. American Society for Radiation Oncology, 2024.
- Allen D, Hosseini M, Ratan R, Nair R, Lu C, Patel S, Ravi V, Halperin D, Busaidy N, Iyer P, Grubbs E, Diaz E, Lango M, Wang R, Zafereo M, Williams M, Cabanillas M, Maniakas A. Unusual Thyroid Pathologies: Presentation, Management, and Clinical Outcomes. Thyroid 33(S1):P-1-A-185, 2023.
- Williams MD. Role of the programmed death-ligand 1 (PD-L1) and antigen presenting natural Killer (AP-NK) cells in immunosuppressive tumor microenvironment (TME) of oral squamous cell carcinomas. 2023 AAOMP Meeting, 2023.
- Contrera K, Ferrarotto R, Gunn G, Su S, Kies M, Glisson B, Garden A, Roberts D, El-Naggar A, Wiilliams M, Raza S, DeMonte F, Chen M, Chambers M, Hanna E. Phase II prospective trial of induction chemotherapy for advanced sinonasal squamous cell or poorly differentiated carcinoma. Journal of Clinical Oncology 41(16_suupl):6090, 2023.
- Fazeli S, Hofmann MC, Gule-Monroe M, McBeath E, Cabanillas M, Busaidy N, Waguespack S, Hu M, Jimenez C, Sherman S, Habra M, Cote G, Bassett R, Williams M, Dadu R. BRAF +/- MEK inhibitor therapy in BRAF V600E-mutated differentiated thyroid carcinoma: Does the presence of a TERT promoter mutation influence therapeutic response?. Thyroid 32(S1), 2022.
- Cabanillas M, Busaidy N, Zafereo M, Gule-Monroe M, Liu S, Ferrarotto R, Lu C, Gross N, Fellman B, Brosu H, Williams M, Iyer P, Maniakas A, Wang J, Dadu R. BRAF/MEK Inhibitor Plus Immunotherapy for BRAFV600E-mutated Anaplastic Thyroid Carcinoma. Thyroid 32(S1), 2022.
- Vodopivec D, Cabanillas M, Busaidy N, Gule-Monroe M, Zafereo M, Wang J, Williams M, Waguespack S, Bassett R, Maniakas A, Lai S, Dadu R. Single Center Experience with the Combination of Lenvatinib and Pembrolizumab for the Treatment of Anaplastic Thyroid Cancer. Journal Of Endocrine Society 6(Supplement_1):A848-49, 2022.
- Gillison M, Williams MD, Johnson J, Leung C, Reddy J, Garden A, Ferrarotto R, Mott F, Le X, Gunn G, Lee A, Fuller C, Lu C, Moreno A, Hutcheson K, Gross N, Lango M, Goepfert R, Myers J, Hanna E, Xiao W, Jiang B, Rudqvist NP, Lee J, Phan J. Phase 2 trial of induction and concomitant CTLA4 (ipilimumab) and PD-1 (nivolumab) immune checkpoint blockade and intensity modulated radiation therapy (IMRT) in HPV-positive oropharyngeal squamous cell carcinoma (HPV-OPSCC). J Immunother Cancer 10(Suppl 2):A594-95, 2022.
- Williams M. Single-cell tumor-infiltrating T cell landscape and dynamics in human papillomavirus positive oropharyngeal squamous cell carcinoma before and during CTLA-4 and PD-1 immune checkpoint blockade. 2022 SITC 37th Annual Meeting & Pre-Conference Programs, 2022.
- Diaz HG, Zafereo M, Vederrabano P, Tufano R, Kowalski L, Simo R, Maruti S, Golbert L, Maniakas A, Wang J, Busaidy N, Williams MD, Luengo P, Gomez J, Pian H, Ruz I, Sune V, Gonzales V, Dominguez JM. New sample-to-result Idylla-ThyroidPrint Assay accurately identifies benign thyroid nodules with indeterminate cytology: A multicenterprospective double-blinded clinical validation trial. European Thyroid Assocaition.
Book Chapters
- Choisea SI, Liu B, Williams MD. Mucoepidermoid Carcinoma. In: World Health Organization Classification of Tumours: Peadiatric Tumours. International Agency for Research on Cancer, 2023.
- Williams MD, Range DE. Thyroid Gland. In: Practical Head and Neck Pathology. Springer, 2020.
- Williams MD, El-Naggar AK. Pathology and Differential Diagnosis of Anterior Skull Base Tumours. In: Adv Otorhinolaryngol, 13-27, 2020.
- Vigneswaran N, Williams MD. Epidemiologic trends in head and neck cancer and aids in diagnosis. In: Oral Maxillofac Surg Clin North Am. 2, 123-41, 2014.
- Williams MD, El-Naggar AK. Chapter 3 Head and Neck Pathology. In: Differential Diagnosis in Surgical Pathology. Third Edition. Elsevier Health Sciences, 2014.
- Williams MD. Pathology of Tumors and Tumor-like Lesions of the Skull Base. In: Comprehensive Management of Skull Base Tumors. First Edition. Informa Heath Care, 43-62, 2008.
Grant & Contract Support
Title: | Fluorescence Spectroscopy to Detect Oral Neoplasm |
Funding Source: | NIH/NCI |
Role: | Co-Investigator |
Title: | Multi-modal Optical Imaging System for Early Detection of Oral Cancer |
Funding Source: | Cancer Prevention & Research Institute of Texas (CPRIT) |
Role: | Co-Investigator |
Title: | Differentiating follicular neoplasms through gene methylation |
Funding Source: | NIH/NCI |
Role: | Principal Investigator |
Title: | Using Dynamic Contrast-Enhanced Magnetic Resonance Imaging (DCE-MRI) to Establish Objective Clinical Outcome Measures for Mandibular Osteoradionecrosis |
Funding Source: | NIH/NIDCR |
Role: | Co-Investigator |
Title: | Sensitizing TP53-Mutant Driven Head and Neck Cancer to Therapy |
Funding Source: | American Cancer Society (ACS) |
Role: | Co-Investigator |
Title: | Multimodal Optical Imaging to Improve Real-Time Margin Assessment During Oral Cancer Surgery |
Funding Source: | NIH/NCI |
Role: | Co-Investigator |
Title: | InHance: Imaging Innovation for Head and Neck Cancer Evaluation & Treatment Delivery |
Funding Source: | NIH/NCI |
Role: | Co-Investigator |
Title: | Blockade of the TGIT immunoregulatory networks in human papillomavirus-associated Head and Neck Cancer |
Funding Source: | NIH/NCI |
Role: | Co-Principal Investigator |
Title: | Spatiotemporal Genomics and Network Analysis of Oncogenic Yap in Oral |
Funding Source: | Baylor College of Medicine |
Role: | Collaborator |
Title: | Defining the Role of L1CAM-EGFR Signaling in Head and Neck Cancer Perineural Invasion and Pain |
Funding Source: | NIH/NCI |
Role: | Co-Investigator |
Title: | OPC Survivor: Optimizing OroPharyngeal Cancer SURVivorship |
Funding Source: | NIH/NCI |
Role: | Co-Investigator |
Title: | Development of MPI for Head and Neck Cancer Sentinel Lymph Node Imaging |
Funding Source: | Magnetic Insight, Inc |
Role: | Co-Investigator |
Title: | Translational studies to enable MPI SLN imaging |
Funding Source: | NIH/NCI |
Role: | Co-Investigator |
Title: | Treatment Optimization for Sinonasal Malignancy with Simulation Models (TOPSS) |
Funding Source: | NIH/NCI |
Role: | Collaborator |
Title: | Neoadjuvant combination anti-PD-L1 and anti-TIGIT immune checkpoint blockade in Oral Cavity Squamous Cell Carcinoma |
Funding Source: | NIH/NCI |
Role: | Co-Principal Investigator |
Title: | A Low-Cost, Rugged, End-to-End System for Slide-Free Pathology Based on Computational Microscopy and Pan-Cancer Targeted Vital Dyes |
Funding Source: | William Marsh Rice University |
Role: | Co-Principal Investigator |
Title: | Defining the Role of Schwann Cell L1CAM-EGFR Signaling in Perineural invasion, Neuroinflammation and Cancer Associated Pain |
Funding Source: | NIH/NCI |
Role: | Contributor |
Title: | Multidimensional atlas of dynamic cellular, morphologic, and microenvironment changes driving progression of oral potentially malignant disorders |
Funding Source: | NIH/NCI |
Role: | Co-Investigator |
Title: | Elucidating subclonal evolution and fitness dynamics oral carcinogenesis |
Funding Source: | NIH/NCI |
Role: | Co-Investigator |
Title: | Facilitating Molecular Screening for NTRK in Thyroid Cancers through Whole Slide Image Analysis |
Funding Source: | Bayer |
Role: | Principal Investigator |
Title: | PRECISE-OPMD Trial: Preventing Cancer through Intratumoral Strategy and Early Biomarker Evaluation in Oral Potentially Malignant Disorders |
Funding Source: | NIH/NCI |
Role: | Co-Investigator |
Title: | I-PROTECT - Intratumoral Prevention and Risk Outcomes in Targeted Early Cancer Treatment with Immunotherapy |
Funding Source: | Cancer Prevention & Research Institute of Texas (CPRIT) |
Role: | Co-Investigator |
Patient Reviews
CV information above last modified September 20, 2024