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      Miriam N. Lango Image

      Miriam N. Lango, MD, FACS

      Department of Head and Neck Surgery, Division of Surgery

      Present Title & Affiliation

      Primary Appointment

      Professor, Head and Neck Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX

      Dual/Joint/Adjunct Appointment

      Professor, Head and Neck Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX

      Education & Training

      Degree-Granting Education

      1996School of Medicine, New York University, New York, New York, US, MD
      1989Barnard College, Columbia University, New York, New York, US, English, BA

      Postgraduate Training

      2021-2022Certificate Program, The University of Texas School of Biomedical Informatics, Houston, Texas
      2003-2004Clinical Fellowship, Reconstructive and Skull Base Surgery, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania
      1998-2003Clinical Residency, Otolaryngology/ Head and Neck Surgery, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania
      1997-1998Clinical Internship, Surgery, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania
      1996-1997Research Fellowship, Otolaryngology, Johns Hopkins University Medical Center, Baltimore, Maryland

      Licenses & Certifications

      2019Physician License
      2004American Board of Otolaryngology

      Experience & Service

      Faculty Academic Appointments

      Professor, Head and Neck Surgery, Fox Chase Cancer Center, Philadelphia, PA, 2018 - 2019

      Associate Professor, Head and Neck Surgery, Temple University School of Medicine, Philadelphia, PA, 2014 - 2019

      Associate Professor, Head and Neck Surgery, Fox Chase Cancer Center, Philadelphia, PA, 2011 - 2018

      Assistant Professor, Head and Neck Surgery, Temple University School of Medicine, Philadelphia, PA, 2004 - 2012

      Assistant Professor, Head and Neck Surgery, Fox Chase Cancer Center, Philadelphia, PA, 2004 - 2011

      Administrative Appointments/Responsibilities

      Safety/Quality Officer, Head and Neck Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX, 2021 - Present

      Extramural Institutional Committee Activities

      Discussant, AHN Virtual Tumor Board, The University of Texas MD Anderson Cancer Center, 2022

      Editorial Activities

      Editorial Board Member, Otolaryngology Head and Neck Surgery, 2020 - 2023

      Honors & Awards

      2021Top 10% Providers, Nationally Ranked Patient Care, Clinical and Group Consumer Assessment of Healthcare Providers and Systems
      2017Induction Triologic Society
      2016 - 2019America’s Top Doctors
      2012 - 2019Top Doctor, Philadelphia Magazine
      2005Institutional Award, American Cancer Society, Grant $20,000
      2002Resident Research Award, American Academy of Otolaryngology
      2000Resident Research Award, American Academy of Otolaryngology

      Professional Memberships

      National Cancer Institute

      2015 - 2022

      American Head and Neck Society

      2013 - Present

      American Academy of Otolaryngology

      2013 - 2019

      Selected Presentations & Talks

      Regional Presentations

      1. 2015. Current and Future Innovations on Larynx Cancer Treatment. Conference. University of Pittsburgh School of Medicine. Pittsburgh, PA, US.
      2. 2014. Thyroid Cancer Update. Conference. Easton Hospital. Easton, PA, US.
      3. 2014. Prognostication in Thyroid Cancer. Conference. Pottstown Hospital. Pottstown, PA, US.
      4. 2014. Academic Affiliation and Medicare Physician Payment in Otolaryngology. Conference. Fox Chase Cancer Center, Temple University Health System. Philadelphia, PA, US.
      5. 2013. General Health Perception and Survival in Head and Neck Cancer Patients. Conference. Fox Chase Cancer Center, Temple University Health System. Philadelphia, PA, US.

      National Presentations

      1. 2021. Indications of PD-1 Inhibitors from Advanced Cutaneous Squamous Cell Carcinoma. Conference. American Head and Neck Society, US.
      2. 2020. Controversies in Thyroidology. Conference. Controversies Regarding the Role of Molecular Testing in Thyroid Nodules: A Case Based Discussion 2020 Webinar Series from the American Thyroid Assoc Panelist, US.
      3. 2019. Benign Thyroid Disease and Well-differentiated Thyroid Cancer. Invited. AAES 2019 Advanced Endocrine Surgery Course. Los Angeles, CA, US.
      4. 2018. The Role of Socioeconomic Status and Trends in Tonsil Cancer Incidence in the United States (2000-2014). Invited. Head and Neck Symposium. Scottsdale, AZ, US.
      5. 2018. History of Blistering Sunburn and Molecular Profile in Melanoma. Invited. Academic Surgical Congress. Jacksonville, FL, US.
      6. 2018. Smoking and Next Generation Sequencing Mutation Signature in Melanoma. Invited. Academic Surgical Congress. Jacksonville, FL, US.
      7. 2017. Trends in Papillary Thyroid Carcinoma Incidence Rates: The Role of Access to Care. Invited. American Association of Endocrine Surgeons. Orlando, FL, US.
      8. 2016. Predictors of Regional Medicare Expenditures for Otolaryngology Physician. Invited. Triological Society 119th Annual Meeting. Chicago, IL, US.
      9. 2016. The Geographic Distribution of the Otolaryngology Workforce in the United. Invited. Triological Society 119th Annual Meeting. Chicago, IL, US.
      10. 2016. Response to Ipilimumab Treatment When Initiated at Different Time Points of the Disease Course in Melanoma. Invited. HEMONC TODAY Melanoma and Cutaneous Malignancies. New York, NY, US.
      11. 2016. Risk of Second Oral Cavity Cancer and Survival after a Primary Solid or Hematological Malignancy. Invited. Head and Neck Symposium. Scottsdale, AZ, US.
      12. 2014. The HPV+ Head and Neck Cancer Epidemic: What you need to Know. Invited. American Academy of Otolaryngology-Head and Neck Surgery. Orlando, FL, US.
      13. 2014. Management of Goiter, Thyroid Surgery in Clinical Practice Guidelines. Conference. American Academy of Otolaryngology. Orlando, FL, US.

      International Presentations

      1. 2017. Why Patients Can’t Swallow. Invited. American Society of Clinical Oncology. Chicago, US.
      2. 2016. Phase II Trial of Carboplatin/Paclitaxel and Cetuximab, Followed by Carboplatin/Paclitaxel/Cetuximab and Erlotinib, in Metastatic or Recurrent Squamous Cell Carcinoma of the Head and Neck. Invited. American Society of Clinical Oncology. Chicago, US.
      3. 2014. Nasopharyngeal Cancer Tumor Board. Invited. International Federation of Head and Neck Oncologic Societies. New York, US.
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      Grant & Contract Support

      Date: 2005 - Present
      Title:Prospective study in swallowing function in head and neck cancer
      Funding Source:American Cancer Society (ACS)
      Role:Investigator
      ID:IRG 856

      Selected Publications

      Peer-Reviewed Articles

      1. Townes TG, Martinez J, Gross ND, Li G, Goepfert R, Myers J, Sikora AG, Choi K, Hutcheson KA, Song W, Lee A, Moran A, Lewis CM, Akhave N, Johnson F, De Sousa LG, Maniakas A, Wang JR, Su SY, Lai SY, Hanna E, Zhao X, Lango MN. A Standardized Algorithm's Impact on Primary Detection in Head and Neck Carcinoma of Unknown Primary. Otolaryngol Head Neck Surg 175(2):385-393, 2026. e-Pub 2026. PMID: 42059064.
      2. Cunningham, C, van Dijk, S, Langer, MM, Moronta, S, Herman, T, Collins, RA, Digennaro, C, Galvan, AK, Varghese, J, Lango, MN, Jalali, MS, Fisher, SB, Grubbs, EG, Donelan, K, Swan, JS. A Thyroid-Cancer-Specific Utility Index. Thyroid : official journal of the American Thyroid Association 36(3):278-290, 2026. e-Pub 2026. PMID: 41735804.
      3. Burtness B, Flamand Y, Quon H, Weinstein GS, Mehra R, Garcia JJ, Kim S, O'Malley BW Jr, Ozer E, Ikpeazu C, Koch WM, Gross ND, Bell RB, Patel M, Lango MN, Morris LG, Smith R, Karakla D, Richmon JD, Holsinger FC, Ferris RL. Long-Term Follow-Up of E3311, an ECOG-ACRIN Cancer Research Group Phase II Trial of Transoral Surgery and Risk-Based Adjuvant Treatment in Human Papillomavirus-Initiated Oropharynx Cancer. J Clin Oncol 43(23):2559-2565, 2025. e-Pub 2025. PMID: 40493877.
      4. Jiang X, Rudqvist NP, Jiang B, Ye S, He S, Liang Q, Dou J, Williams MD, Dunn JD, Johnson JM, Akagi K, Xiao W, Liang S, Elayavalli S, Sun B, Parra ER, Ferrarotto R, Garden AS, Fuller CD, Reddy J, Gross ND, Lango MN, Leung CH, Liu S, Liu DD, Li M, Lee JJ, Curran MA, Phan J, Chen K, Gillison ML. Depletion of Effector Regulatory T Cells Associates with Major Response to Induction Dual Immune Checkpoint Blockade. Cancer Discov 15(8):1569-1592, 2025. e-Pub 2025. PMID: 40249124.
      5. Working Group MOCEEA, Sahin O, Kamel S, Wahid KA, Dede C, Taku N, He R, Naser MA, Sharafi S, Mäkitie A, Kann BH, Kaski K, Sahlsten J, Jaskari J, Amit M, Chronowski GM, Diaz EM, Garden AS, Goepfert RP, Guenette JP, Gunn GB, Hirvonen J, Hoebers F, Hutcheson KA, Guha-Thakurta N, Johnson J, Kaya D, Khanpara SD, Nyman K, Lai SY, Lango M, Learned KO, Lee A, Lewis CM, Maniakas A, Moreno AC, Myers JN, Phan J, Pytynia KB, Rosenthal DI, Sandulache VC, Schellingerhout D, Shah SJ, Sikora AG, Mohamed ASR, Chen MM, Fuller CD. International Multi-Specialty Expert Physician Preoperative Identification of Extranodal Extension n Oropharyngeal Cancer Patients using Computed Tomography: Prospective Blinded Human Inter-Observer Performance Evaluation. medRxiv, 2024. e-Pub 2024. PMID: 36865096.
      6. Anderson BJ, Moreno AC, Qing Y, Lee JJ, Johnson FM, Lango MN, Barbon CEA, Tripuraneni L, Sahli A, Piper V, Gross N, Fuller CD, Lai SY, Myers JN, Hutcheson KA. Revisiting Feeding Tube Utilization in Oropharynx Cancer: 6-Year Prospective Registry Analysis. Otolaryngol Head Neck Surg 170(5):1319-1330, 2024. e-Pub 2024. PMID: 38353360.
      7. Lango MN. Circulating Human Papillomavirus Tumor DNA-Ready for Prime Time?. JAMA Otolaryngol Head Neck Surg 149(11):978-979, 2023. e-Pub 2023. PMID: 37422914.
      8. Contrera KJ, Tam S, Pytynia K, Diaz EM, Hessel AC, Goepfert RP, Lango M, Su SY, Myers JN, Weber RS, Eguia A, Pisters PWT, Adair DK, Nair AS, Rosenthal DI, Mayo L, Chronowski GM, Zafereo ME, Shah SJ. Impact of Cancer Care Regionalization on Patient Volume. Ann Surg Oncol 30(4):2331-2338, 2023. e-Pub 2023. PMID: 36581726.
      9. Contrera KJ, Tam S, Pytynia K, Diaz EM, Hessel AC, Goepfert RP, Lango M, Su SY, Myers JN, Weber RS, Eguia A, Pisters PWT, Adair DK, Nair AS, Rosenthal DI, Mayo L, Chronowski GM, Zafereo ME, Shah SJ. ASO Visual Abstract: Impact of Cancer Care Regionalization on Patient Volume. Ann Surg Oncol 30(4):2341-2342, 2023. e-Pub 2023. PMID: 36720835.
      10. Karcioglu AS, Dhillon VK, Davies L, Stack BC, Bloom G, Randolph G, Lango MN. Analysis of Unmet Information Needs Among Patients With Thyroid Cancer. JAMA Otolaryngol Head Neck Surg 149(2):110-119, 2023. e-Pub 2023. PMID: 36580287.
      11. Ferris RL, Flamand Y, Weinstein GS, Li S, Quon H, Mehra R, Garcia JJ, Chung CH, Gillison ML, Duvvuri U, O'Malley BW, Ozer E, Thomas GR, Koch WM, Gross ND, Bell RB, Saba NF, Lango MN, Méndez E, Burtness B. Phase II Randomized Trial of Transoral Surgery and Low-Dose Intensity Modulated Radiation Therapy in Resectable p16+ Locally Advanced Oropharynx Cancer: An ECOG-ACRIN Cancer Research Group Trial (E3311). J Clin Oncol 40(2):JCO2101752, 2022. e-Pub 2022. PMID: 34699271.
      12. Awan MJ, Gittleman H, Barnholtz-Sloan J, Machtay M, Nguyen-Tan PF, Rosenthal DI, Schultz C, Huth BJ, Thorstad WL, Frank SJ, Kim H, Foote RL, Lango MN, Shenouda G, Suntharalingam M, Harris J, Zhang Q, Le QT, Yao M, Group NRG. Risk groups of laryngeal cancer treated with chemoradiation according to nomogram scores - A pooled analysis of RTOG 0129 and 0522. Oral Oncol 116:105241, 2021. e-Pub 2021. PMID: 33640577.
      13. Harounian JA, Molin N, Galloway TJ, Ridge D, Bauman J, Farma J, Reddy S, Lango MN. Effect of Sentinel Lymph Node Biopsy and LVI on Merkel Cell Carcinoma Prognosis and Treatment. Laryngoscope 131(3):E828-E835, 2021. e-Pub 2021. PMID: 32663337.
      14. Lee DY, Abraham J, Ross E, Ridge JA, Lango MN, Liu JC, Bauman JR, Avkshtol V, Galloway TJ. Rapid recurrence in head and neck cancer: Underappreciated problem with poor outcome. Head Neck 43(1):212-222, 2021. e-Pub 2021. PMID: 32989878.
      15. Khan SA, Burke M, Zhu F, Yang DH, Dubyk C, Mehra R, Lango MN, Ridge JA, Sher DJ, Burtness B. Survivin expression and impact on head and neck cancer outcomes. Oral Oncol 112:105049, 2021. e-Pub 2021. PMID: 33221541.
      16. Ebersole B, Moran K, Gou J, Ridge J, Schiech L, Liu JC, Lango MN. Heat and moisture exchanger cassettes: Results of a quality/safety initiative to reduce postoperative mucus plugging after total laryngectomy. Head Neck 42(9):2453-2459, 2020. e-Pub 2020. PMID: 32445222.
      17. Dhillon VK, Silver Karcioglu A, Bloom G, Randolph G, Lango MN. What the thyroid cancer patient wants to know: ThyCa survey by the American Head and Neck Society Endocrine Surgery Section. Head Neck 42(9):2496-2504, 2020. e-Pub 2020. PMID: 32530116.
      18. Lango MN. How did we get here? Short history of COVID-19 and other coronavirus-related epidemics. Head Neck 42(7):1535-1538, 2020. e-Pub 2020. PMID: 32445249.
      19. Ebersole B, Lango MN, Ridge J. Dysphagia Screening for Pneumonia Prevention in a Cancer Hospital: Results of a Quality/Safety Initiative. Otolaryngol Head Neck Surgery. e-Pub 2019.
      20. Roldan CS, Chen JJ, Fareed MM, Hameed MY, Churilla TM, Lango MN, Galloway TJ. Impact of primary tumor-specific growth rate on treatment failure for nonoropharyngeal head and neck cancers. Laryngoscope. e-Pub 2019. PMID: 31714626.
      21. Lee CT, Lehrer EJ, Aphale A, Lango M, Galloway TJ, Zaorsky NG. Surgical excision, Mohs micrographic surgery, external-beam radiotherapy, or brachytherapy for indolent skin cancer: An international meta-analysis of 58 studies with 21,000 patients. Cancer 125(20):3582-3594, 2019. e-Pub 2019. PMID: 31355928.
      22. Dong Y, Ridge JA, Ebersole B, Li T, Lango MN, Churilla TM, Donocoff K, Bauman JR, Galloway TJ. Incidence and outcomes of radiation-induced late cranial neuropathy in 10-year survivors of head and neck cancer. Oral Oncol 95:59-64, 2019. e-Pub 2019. PMID: 31345395.
      23. Tang J, Lango MN. Diverging incidence trends for larynx and tonsil cancer in low socioeconomic regions of the US. Oral Oncol 91:65-68, 2019. e-Pub 2019. PMID: 30926064.
      24. Ebersole B, Soni RS, Moran K, Lango MN, Devarajan K, Jamal N. The Influence of Occupation on Self-perceived Vocal Problems in Patients With Voice Complaints. J Voice 32(6):673-680, 2018. e-Pub 2018. PMID: 28967587.
      25. Moten AS, Lango MN, Goel N, Goldberg AJ. Regional diagnostic rates, treatments, and outcomes among patients with invasive ductal carcinoma. J Surg Res 229:114-121, 2018. e-Pub 2018. PMID: 29936977.
      26. Zuniga SA, Lango MN. Effect of rural and urban geography on larynx cancer incidence and survival. Laryngoscope 128(8):1874-1880, 2018. e-Pub 2018. PMID: 29238975.
      27. Ebersole B, Soni RS, Moran K, Lango MN, Devarajan K, Jamal N. The Role of Occupational Voice Demand and Patient-Rated Impairment in Predicting Voice Therapy Adherence. J Voice 32(3):325-331, 2018. e-Pub 2018. PMID: 28709763.
      28. Dong Y, Ridge JA, Li T, Lango MN, Churilla TM, Bauman JR, Galloway TJ. Long-term toxicities in 10-year survivors of radiation treatment for head and neck cancer. Oral Oncol 71:122-128, 2017. e-Pub 2017. PMID: 28688679.
      29. Wang LS, Handorf EA, Ridge JA, Burtness BA, Lango MN, Mehra R, Liu JC, Galloway TJ. Lymph-node-positive cutaneous nonmelanoma skin cancer: A poor-prognosis disease in need of treatment intensification. Ear Nose Throat Journal 96:E12-E18, 2017. e-Pub 2017. PMID: 28719713.
      30. Smith A, Handorf E, Arjmand E, Lango MN. Predictors of regional Medicare expenditures for otolaryngology physician services. Laryngoscope 127(6):1312-1317, 2017. e-Pub 2017. PMID: 27859299.
      31. Liu JC, Sopka DS, Mehra R, Lango MN, Fundakowski C, Ridge JA, Galloway TJ. Early oral tongue cancer initially managed with surgery alone: Treatment of recurrence. World J Otorhinolaryngol Head Neck Surg 2:193-197, 2016. e-Pub 2016. PMID: 29204565.
      32. Beck TN, Georgopoulos R, Shagisultanova EI, Sarcu D, Handorf EA, Dubyk C, Lango MN, Ridge JA, Astsaturov I, Serebriiskii IG, Burtness BA, Mehra R, Golemis EA. EGFR and RB1 as dual biomarkers in HPV-negative head and neck cancer. Mol Cancer Ther 15(10):2486-2497, 2016. e-Pub 2016. PMID: 27507850.
      33. Koshkareva Y, Liu JC, Lango MN, Galloway T, Gaughan JP, Ridge JA. Cervical metastasis in squamous cell carcinoma of the hard palate and maxillary alveolus. Ear Nose Throat J 95(10-11):E6-E11, 2016. e-Pub 2016. PMID: 27792826.
      34. Lango MN, Galloway TJ, Mehra R, Ebersole B, Liu JC, Moran K, Ridge JA. Impact of baseline patient-reported dysphagia on acute gastrostomy placement in patients with head and neck squamous cell carcinoma undergoing definitive radiation. Head Neck 38 Suppl 1:E1318-24, 2016. e-Pub 2016. PMID: 26332292.
      35. Aaron H, Azadarmaki R, Lango MN. Unilateral vocal cord motion impairment after 1 dose of Vincristine: Case report and literature review. Am J Ther 23(2):e621-3, 2016. e-Pub 2016. PMID: 25738569.
      36. Azadarmaki R, Then MT, Walia R, Lango MN. Cavernous hemangioma of the submandibular gland with parapharyngeal extension in an adult: Case report. Ear Nose Throat J 95(2):E11-3, 2016. e-Pub 2016. PMID: 26930336.
      37. Lango MN, Handorf E, Arjmand E. The geographic distribution of the otolaryngology workforce in the United States. Laryngoscope 127(1):95-101, 2016. e-Pub 2016. PMID: 27774588.
      38. Beck TN, Kaczmar J, Handorf E, Nikonova A, Dubyk C, Peri S, Lango MN, Ridge JA, Serebriiskii IG, Burtness B, Golemis EA, Mehra R. Phospho-T356RB1 predicts survival in HPV-negative squamous cell carcinoma of the head and neck. Oncotarget 6(22):18863-74, 2015. e-Pub 2015. PMID: 26265441.
      39. Cracchiolo J, Ridge JA, Egleston B, Lango MN. Practice arrangement and Medicare physician payment in otolaryngology. Otolaryngol Head Neck Surg 152(6):979-87, 2015. e-Pub 2015. PMID: 26034098.
      40. Keller LM, Galloway TJ, Holdbrook T, Ruth K, Yang D, Dubyk C, Flieder D, Lango MN, Mehra R, Burtness B, Ridge JA. p16 status, pathologic and clinical characteristics, biomolecular signature, and long-term outcomes in head and neck squamous cell carcinomas of unknown primary. Head Neck 36(12):1677-84, 2014. e-Pub 2014. PMID: 24115269.
      41. Fang CY, Egleston BL, Ridge JA, Lango MN, Bovbjerg DH, Studts JL, Burtness BA, Einarson MB, Klein-Szanto AJ. Psychosocial functioning and vascular endothelial growth factor in patients with head and neck cancer. Head Neck 36(8):1113-9, 2014. e-Pub 2014. PMID: 23804308.
      42. Lango MN, Egleston B, Fang C, Burtness B, Galloway T, Liu J, Mehra R, Ebersole B, Moran K, Ridge JA. Baseline health perceptions, dysphagia, and survival in patients with head and neck cancer. Cancer 120(6):840-7, 2014. e-Pub 2014. PMID: 24352973.
      43. Doss M, Kolb HC, Walsh JC, Mocharla V, Fan H, Chaudhary A, Zhu Z, Alpaugh RK, Lango MN, Yu JQ. Biodistribution and radiation dosimetry of 18F-CP-18, a potential apoptosis imaging agent, as determined from PET/CT scans in healthy volunteers. J Nucl Med 54(12):2087-92, 2013. e-Pub 2013. PMID: 24136934.
      44. Mehra R, Zhu F, Yang DH, Cai KQ, Weaver J, Singh MK, Nikonova AS, Golemis EA, Flieder DB, Cooper HS, Lango MN, Ridge JA, Burtness B. Quantification of excision repair cross-complementing group 1 and survival in p16-negative squamous cell head and neck cancers. Clin Cancer Res 19(23):6633-43, 2013. e-Pub 2013.
      45. Sopka DM, Li T, Lango MN, Mehra R, Liu JC, Burtness B, Flieder DB, Ridge JA, Galloway TJ. Dysplasia at the margin? Investigating the case for subsequent therapy in 'low-risk' squamous cell carcinoma of the oral tongue. Oral Oncol 49(11):1083-7, 2013. e-Pub 2013. PMID: 24054332.
      46. Lango MN, Flieder D, Arrangoiz R, Veloski C, Yu JQ, Li T, Burtness B, Mehra R, Galloway T, Ridge JA. Extranodal extension of metastatic papillary thyroid carcinoma: correlation with biochemical endpoints, nodal persistence, and systemic disease progression. Thyroid 23(9):1099-105, 2013. e-Pub 2013. PMID: 23421588.
      47. Tejani MA, Galloway TJ, Lango MN, Ridge JA, von Mehren M. Head and neck sarcomas: a comprehensive cancer center experience. Cancers (Basel) 5(3):890-900, 2013. e-Pub 2013. PMID: 24202325.
      48. Galloway TJ, Lango MN, Burtness B, Mehra R, Ruth K, Ridge JA. Unilateral neck therapy in the human papillomavirus ERA: accepted regional spread patterns. Head Neck 35(2):160-4, 2013. e-Pub 2013. PMID: 22302641.
      49. Fang CY, Longacre ML, Manne SL, Ridge JA, Lango MN, Burtness BA. Informational needs of head and neck cancer patients. Health Technol (Berl) 2(1):57-62, 2012. e-Pub 2012. PMID: 22518350.
      50. Andrews G, Lango MN, Cohen R, Feigenberg S, Burtness B, Mehra R, Ahmed S, Nicolaou N, Gaughan J, Ridge JA. Nonsurgical management of oropharyngeal, laryngeal, and hypopharyngeal cancer: the Fox Chase Cancer Center experience. Head Neck 33(10):1433-40, 2011. e-Pub 2011. PMID: 21928415.
      51. Turaka A, Li T, Nicolaou N, Lango MN, Burtness B, Horwitz EM, Ridge JA, Feigenberg SJ. Use of a conventional low neck field (LNF) and intensity-modulated radiotherapy (IMRT): no clinical detriment of IMRT to an anterior LNF during the treatment of head-and neck-cancer. Int J Radiat Oncol Biol Phys 79(1):65-70, 2011. e-Pub 2011. PMID: 20385457.
      52. Turaka A, Li T, Sharma NK, Li L, Nicolaou N, Mehra R, Burtness B, Cohen RB, Lango MN, Horwitz EM, Ridge JA, Feigenberg SJ. Increased recurrences using intensity-modulated radiation therapy in the postoperative setting. Am J Clin Oncol 33(6):599-603, 2010. e-Pub 2010. PMID: 21063195.
      53. Rusthoven KE, Feigenberg SJ, Raben D, Kane M, Song JI, Nicolaou N, Mehra R, Burtness B, Ridge J, Swing R, Lango MN, Cohen R, Jimeno A, Chen C. Initial results of a Phase I dose-escalation trial of concurrent and maintenance erlotinib and reirradiation for recurrent and new primary head-and-neck cancer. Int J Radiat Oncol Biol Phys 78(4):1020-5, 2010. e-Pub 2010. PMID: 20231078.
      54. Lango MN, Egleston B, Ende K, Feigenberg S, D'Ambrosio DJ, Cohen RB, Ahmad S, Nicolaou N, Ridge JA. Impact of neck dissection on long-term feeding tube dependence in patients with head and neck cancer treated with primary radiation or chemoradiation. Head Neck 32(3):341-7, 2010. e-Pub 2010. PMID: 19693946.
      55. Lango MN, Andrews GA, Ahmad S, Feigenberg S, Tuluc M, Gaughan J, Ridge JA. Postradiotherapy neck dissection for head and neck squamous cell carcinoma: pattern of pathologic residual carcinoma and prognosis. Head Neck 31(3):328-37, 2009. e-Pub 2009. PMID: 18853450.
      56. Feigenberg SJ, Lango MN, Nicolaou N, Ridge JA. Intensity-modulated radiotherapy for early larynx cancer: is there a role?. Int J Radiat Oncol Biol Phys 68(1):2-3, 2007. e-Pub 2007. PMID: 17448864.
      57. Sok JC, Coppelli FM, Thomas SM, Lango MN, Xi S, Hunt JL, Freilino ML, Graner MW, Wikstrand CJ, Bigner DD, Gooding WE, Furnari FB, Grandis JR. Mutant epidermal growth factor receptor (EGFRvIII) contributes to head and neck cancer growth and resistance to EGFR targeting. Clin Cancer Res 12(17):5064-73, 2006. e-Pub 2006. PMID: 16951222.
      58. Lango MN, Wentzel AL, Song JI, Xi S, Johnson DE, Lamph WW, Miller L, Grandis JR. Responsiveness to the retinoic acid receptor-selective retinoid LGD1550 correlates with abrogation of transforming growth factor alpha/epidermal growth factor receptor autocrine signaling in head and neck squamous carcinoma cells. Clin Cancer Res 9(11):4205-13, 2003. e-Pub 2003. PMID: 14519647.
      59. Lango MN, Dyer KF, Lui VW, Gooding WE, Gubish C, Siegfried JM, Grandis JR. Gastrin-releasing peptide receptor-mediated autocrine growth in squamous cell carcinoma of the head and neck. J Natl Cancer Inst 94(5):375-83, 2002. e-Pub 2002. PMID: 11880476.
      60. Song JI, Lango MN, Hwang JD, Drenning SD, Zeng Q, Lamph WW, Grandis JR. Abrogation of transforming growth factor-alpha/epidermal growth factor receptor autocrine signaling by an RXR-selective retinoid (LGD1069, Targretin) in head and neck cancer cell lines. Cancer Res 61(15):5919-25, 2001. e-Pub 2001. PMID: 11479234.
      61. Endo S, Zeng Q, Burke NA, He Y, Melhem MF, Watkins SF, Lango MN, Drenning SD, Huang L, Rubin Grandis J. TGF-alpha antisense gene therapy inhibits head and neck squamous cell carcinoma growth in vivo. Gene Ther 7(22):1906-14, 2000. e-Pub 2000. PMID: 11127578.
      62. Shah SI, Yip L, Greenberg B, Califano JA, Chow J, Eisenberger CF, Lee DJ, Sewell DA, Reed AL, Lango MN, Jen J, Koch WM, Sidransky D. Two distinct regions of loss on chromosome arm 4q in primary head and neck squamous cell carcinoma. Arch Otolaryngol Head Neck Surg 126(9):1073-6, 2000. e-Pub 2000.
      63. Koch WM, Lango M, Sewell D, Zahurak M, Sidransky D. Head and neck cancer in nonsmokers: a distinct clinical and molecular entity. Laryngoscope 109(10):1544-51, 1999. e-Pub 1999.
      64. Linn JF, Lango M, Halachmi S, Schoenberg MP, Sidransky D. Microsatellite analysis and telomerase activity in archived tissue and urine samples of bladder cancer patients. Int J Cancer 19(74):625-9, 1997. e-Pub 1997. PMID: 9421360.
      65. Donohue TJ, Dworkin LD, Ma J, Lango MN, Catanese VM. Antihypertensive agents that limit ventricular hypertrophy inhibit cardiac expression of insulin-like growth factor-I. J Investig Med 45(9):625-9, 1997. e-Pub 1997. PMID: 9444886.
      66. Lee DJ, Koch WM, Yoo G, Lango M, Reed A, Califano J, Brennan JA, Westra WH, Zahurak M, Sidransky D. Impact of chromosome 14q loss on survival in primary head and neck squamous cell carcinoma. Clinical Cancer Res 3(4):501-5, 1997. e-Pub 1997.
      67. Califano JA, Johns MM 3rd, Westra WH, Lango MN, Eisele D, Saji M, Zeiger MA, Udelsman R, Koch WM, Sidransky D. An allelotype of papillary thyroid cancer. Int J Cancer 69(6):442-4, 1996. e-Pub 1996. PMID: 8980243.
      68. Califano JA, MMrd J, Westra WH, Lango MN, Eisele D, Saji M, Zeiger MA, Udelsman R, Koch WM, Sidransky D. An allelotype of papillary thyroid cancer. Int J Cancer 20(69):442-4, 1996. e-Pub 1996.
      69. Donohue TJ, Dworkin LD, Lango MN, Fliegner K, Lango RP, Benstein JA, Slater WR, Catanese VM. Induction of myocardial insulin-like growth factor-I gene expression in left ventricular hypertrophy. Circulation 89(2):799-809, 1994. e-Pub 1994. PMID: 8313569.
      70. Donohue TJ, Dworkin LD, Lango MN, Fliegner K, Lango RP, Benstein JA, Slater WR, Catanese VM. Induction of myocardial insulin-like growth factor-I gene expression in left ventricular hypertrophy. Circulation 89(2):799-809, 1994. e-Pub 1994.
      71. Catanese VM, Sciavolino PJ, Lango MN. Discordant, organ-specific regulation of insulin-like growth factor-I messenger ribonucleic acid in insulin-deficient diabetes in rats. Endocrinology 132(2):496-503, 1993. e-Pub 1993. PMID: 8425471.
      72. Catanese VM, Sciavolino PJ, Lango MN. Discordant, organ-specific regulation of insulin-like growth factor-I messenger ribonucleic acid in insulin-deficient diabetes in rats. Endocrinology 132(2):496-503, 1993. e-Pub 1993.

      Invited Articles

      1. Zafereo M, Yu J, Angelos P, Brumund K, Chuang HH, Goldenberg D, Lango MN, Perrier N, Randolph G, Shindo ML, Singer M, Smith R, Stack BC, Steward D, Terris DJ, Vu T, Yao M, Tufano RP. American Head and Neck Society Endocrine Surgery Section update on parathyroid imaging for surgical candidates with primary hyperparathyroidism. Head Neck 41(7):2398-2409, 2019. e-Pub 2019. PMID: 31002214.
      2. Westerberg BD, Lango MN. Otolaryngology-Related Disorders in Underserved Populations, Otolaryngology Training and Workforce Considerations in North America. Otolaryngol Clin North Am 51(3):685-695, 2018. e-Pub 2018. PMID: 29482920.

      Review Articles

      1. Glaun MDE, Feng Z, Lango MN. Management of Regional Lymph Nodes in Head and Neck Melanoma. Oral Maxillofac Surg Clin North Am 34(2):273-281, 2022. e-Pub 2022. PMID: 35400571.
      2. Lango MN, Shnayder Y. Surgical Management of Merkel Cell Carcinoma. Otolaryngol Clin North Am 54(2):357-368, 2021. e-Pub 2021. PMID: 33602514.
      3. Head MD, Guidelines Consortium NST, members C, Maniakas A, Jozaghi Y, Zafereo ME, Sturgis EM, Su SY, Gillenwater AM, Gidley PW, Lewis CM, Diaz E, Goepfert RP, Kupferman ME, Gross ND, Hessel AC, Pytynia KB, Nader ME, Wang JR, Lango MN, Kiong KL, Guo T, Zhao X, CMKL Y, Appelbaum E, Alpard J, Garcia JA, Terry S, Flynn JE, Bauer S, Fournier D, Burgess CG, Wideman C, Johnston M, You C, De Luna R, Joseph L, Diersing J, Prescott K, Heiberger K, Mugartegui L, Rodriguez J, Zendehdel S, Sellers J, Friddell RA, Thomas A, Khanjae SJ, Schwarzlose KB, Chambers MS, Hofstede TM, Cardoso RC, Wesson RA, Won A, Otun AO, Gombos DS, Al-Zubidi N, Hutcheson KA, Gunn GB, Rosenthal DI, Gillison ML, Ferrarotto R, Weber RS, Hanna EY, Myers JN, Lai SY. Head and neck surgical oncology in the time of a pandemic: Subsite-specific triage guidelines during the COVID-19 pandemic. Head Neck 42(6):1194-1201, 2020. e-Pub 2020. PMID: 32342541.
      4. Tamaki A, Miles BA, Lango MN, Kowalski L, Zender CA. AHNS Series: Do you know your guidelines? Review of current knowledge on laryngeal cancer. Head Neck 40(1):170-181, 2018. e-Pub 2018. PMID: 29076227.
      5. Patel SA, Abdollahi H, Ridge JA, Chang EI, Lango MN, Topham NS. Asymptomatic deep peroneal vein thrombosis during free fibula flap harvest: A review of the literature, strategies for preoperative assessment, and an algorithm for reconstruction. Ann Plast Surg 76(4):468-71, 2016. e-Pub 2016. PMID: 25275472.
      6. Arrangoiz R, Galloway TJ, Papavasiliou P, Ridge JA, Lango MN. Metastatic cervical carcinoma from an unknown primary: literature review. Ear Nose Throat J 93(4-5):E1-10, 2014. e-Pub 2014. PMID: 24817234.
      7. Azadarmaki R, Lango MN. Malignant transformation of respiratory papillomatosis in a solid-organ transplant patient: case report and literature review. Ann Otol Rhinol Laryngol 122(7):457-60, 2013. e-Pub 2013. PMID: 23951698.
      8. Lango MN, Topham NS, Perlis CS, Flieder DB, Weaver MW, Turaka A, Patel SA, Ridge JA. Surgery in the multimodality treatment of sinonasal malignancies. Curr Probl Cancer 34(5):304-21, 2010. e-Pub 2010. PMID: 20851263.
      9. Lango MN. Multimodal treatment for head and neck cancer. Surg Clin North Am 89(1):43-52, viii, 2009. e-Pub 2009. PMID: 19186230.
      10. Lango MN, Myers JN, Garden AS. Controversies in surgical management of the node-positive neck after chemoradiation. Semin Radiat Oncol 19(1):24-8, 2009. e-Pub 2009. PMID: 19028342.
      11. Brown KM, Lango MN, Ridge JA. The role of neck dissection in the combined modality therapy setting. Semin Oncol 35(3):229-35, 2008. e-Pub 2008. PMID: 18544438.
      12. Lango MN, Shin DM, Grandis JR. Targeting growth factor receptors: integration of novel therapeutics in the management of head and neck cancer. Curr Opin Oncol 13(3):168-75, 2001. e-Pub 2001. PMID: 11307060.

      Other Articles

      1. Fundakowski CE, Lango MN Considerations in surgical versus non-surgical management of HPV positive oropharyngeal cancer. Cancers Head Neck 1:6, 2016. PMID: 31093336.

      Editorials

      1. Westerberg BD, Lango MN. Otolaryngology-Related Disorders in Underserved Populations, Otolaryngology Training and Workforce Considerations in North America. Otolaryngol Clin North American 51(2):685-695, 2018.
      2. Tamaki A, Miles BA, Lango MN, Kowalski L, Zender CA. AHNS Series: Do you know your guidelines? Review of current knowledge on laryngeal cancer. Head Neck 40(1):170-18, 2018.
      3. Azadarmaki R, Lango MN. Malignant transformation of respiratory papillomatosis in a solid-organ transplant patient: case report and literature review. Ann Otol Rhinol Laryngol 122(7):457-60, 2013.
      4. Tejani MA, Galloway TJ, Lango MN, Ridge JA, von Mehren M. Head and Neck Sarcomas: a Comprehensive Cancer Center Experience. Cancers (Basel) 5(3):890-900, 2013.
      5. Lango MN, Topham NS, Perlis CS, Flieder DB, Weaver MW, Turaka A, Patel SA, Ridge JA. Surgery in the multimodality treatment of sinonasal malignancies. Curr Probl Cancer 34(5):304-21, 2010.
      6. Lango MN. Multimodal treatment for head and neck cancer. Surg Clin North Am 89(1):43-52, 2009.
      7. Lango MN, Myers JN, Garden AS. Controversies in surgical management of the node-positive neck after chemoradiation. Semin Radiat Oncol 19(1):24-8, 2009.
      8. Brown KM, Lango MN, Ridge JA. The role of neck dissection in the combined modality therapy setting. Semin Oncol 35(3):229-35, 2008.
      9. Feigenberg SJ, Lango MN, Nicolaou N, Ridge JA. Intensity-modulated radiotherapy for early larynx cancer: is there a role?. Int J Radiat Oncol Biol Phys 68(1):2-3, 2007.
      10. Battineni ML, Galetta SL, Oh J, Lango MN, Brooks JJ, Schuster SJ, Loevner LA. Idiopathic hypereosinophilic syndrome with skull base involvement. AJNR Am J Neuroradiol 28(5):971-3, 2007.
      11. Lango MN, Shin DM, Grandis JR. Targeting growth factor receptors: integration of novel therapeutics in the management of head and neck cancer. Curr Opin Oncol 13(3):168-75, 2001.

      Abstracts

      1. Tang JA, Garden A, Myers JN, Hessel AC, Lewis CM, Moreno A, Z-H L, Akhave N, Taylor J, Lango MN. Poster presentation at the American College of Surgeons (ACS) Quality and Safety Conference 2024. Identifying Targets of Quality Improvement for Timely Adjuvant Radiation Therapy in Head and Neck Cancers, 2024. e-Pub 2024.

      Book Chapters

      1. Lango MN. Partial Glossectomy. In: Operative Otolaryngology-Head and Neck Surgery. 3rd. Elsevier Ltd, 2018.
      2. Lango MN. Massive and Xubsternal Goiter. In: Operative Otolaryngology-Head and Neck Surgery. 3rd. Elsevier Ltd, 2018.
      3. Lango MN. NRG Broadcast Distribution List. In: Operative Otolaryngology-Head and Neck Surgery. 3rd. Elsevier Ltd, 2018.
      4. Ridge JA, Mehra R, Lango MN, Feigenberg S. Head and Neck Tumors. In: Cancer Management: A Multidisciplinary Approach. 13th edition. 13th. UBM Medica, 1-50, 2014.
      5. Lango MN, Ridge JA. Lymph node dissection for thyroid cancer. In: Atlas of Endocrine Surgical Techniques. Saunders, 72-85, 2010.
      6. Lango MN, Chalian AA. Overview of Head and Neck Cancer. In: Geriatric Otolaryngology. Taylor & Francis, 471-82, 2006.
      7. Lango MN, O'Malley B, Chalian AA. American College of Surgeons. Neck Dissection. In: ACS Surgery: Principles and Practice. 2nd. WebMD Professional Publishing, 2004.
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      CV information above last modified August 06, 2026

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