Parmeswaran Diagaradjane, Ph.D., DABR

Peer-Reviewed Articles

1. Smith DL, Debeb BG, Diagaradjane P, Larson R, Kumar S, Ning J, Lacerda L, Li L, Woodward WA. Prophylactic cranial irradiation reduces the incidence of brain metastasis in a mouse model of metastatic, HER2-positive breast cancer. Genes Cancer 12:28-38, 2021. e-Pub 2021. PMID: 33884104.
2. Han EY, Diagaradjane P, Luo D, Ding Y, Kalaitzakis G, Zoros E, Zourari K, Boursianis T, Pappas E, Wen Z, Wang J, Briere TM. Validation of PTV margin for Gamma Knife Icon frameless treatment using a PseudoPatient® Prime anthropomorphic phantom. J Appl Clin Med Phys 21(9):278-285, 2020. e-Pub 2020. PMID: 32786141.
3. Manohar N, Reynoso F, Jayarathna S, Moktan H, Ahmed MF, Diagaradjane P, Krishnan S, Cho SH. High-sensitivity imaging and quantification of intratumoral distributions of gold nanoparticles using a benchtop x-ray fluorescence imaging system. Opt Lett 44(21):5314-5317, 2019. PMID: 31674996.
4. Debeb BG, Lacerda L, Anfossi S, Diagaradjane P, Chu K, Bambhroliya A, Huo L, Wei C, Larson RA, Wolfe AR, Xu W, Smith DL, Li L, Ivan C, Allen PK, Wu W, Calin GA, Krishnamurthy S, Zhang XH, Buchholz TA, Ueno NT, Reuben JM, Woodward WA. miR-141-Mediated Regulation of Brain Metastasis From Breast Cancer. J Natl Cancer Inst 108(8), 2016. e-Pub 2016. PMID: 27075851.
5. Manohar N, Reynoso FJ, Diagaradjane P, Krishnan S, Cho SH. Quantitative imaging of gold nanoparticle distribution in a tumor-bearing mouse using benchtop x-ray fluorescence computed tomography. Sci Rep 6:22079, 2016. e-Pub 2016. PMID: 26912068.
6. Wolfe AR, Debeb BG, Lacerda L, Larson R, Bambhroliya A, Huang X, Bertucci F, Finetti P, Birnbaum D, Van Laere S, Diagaradjan P, Ruffell B, Trenton NJ, Chu K, Hittelman W, Diehl M, Levental I, Ueno NT, Woodward WA. Simvastatin prevents triple-negative breast cancer metastasis in pre-clinical models through regulation of FOXO3a. Breast Cancer Res Treat 154(3):495-508, 2015. e-Pub 2015. PMID: 26590814.
7. Deorukhkar A, Ahuja N, Mercado AL, Diagaradjane P, Raju U, Patel N, Mohindra P, Diep N, Guha S, Krishnan S. Zerumbone increases oxidative stress in a thiol-dependent ROS-independent manner to increase DNA damage and sensitize colorectal cancer cells to radiation. Cancer Med 4(2):278-92, 2015. e-Pub 2014. PMID: 25450478.
8. Chatterjee DK, Wolfe T, Lee J, Brown AP, Singh PK, Bhattarai SR, Diagaradjane P, Krishnan S. Convergence of nanotechnology with radiation therapy-insights and implications for clinical translation. Transl Cancer Res 2(4):256-268, 2013. PMID: 25279336.
9. Prasad S, Yadav VR, Sung B, Reuter S, Kannappan R, Deorukhkar A, Diagaradjane P, Wei C, Baladandayuthapani V, Krishnan S, Guha S, Aggarwal BB. Ursolic Acid Inhibits Growth and Metastasis of Human Colorectal Cancer in an Orthotopic Nude Mouse Model by Targeting Multiple Cell Signaling Pathways: Chemosensitization with Capecitabine. Clin Cancer Res 18(18):4942-53, 2012. e-Pub 2012. PMID: 22832932.
10. Kunnumakkara AB, Sung B, Ravindran J, Diagaradjane P, Deorukhkar A, Dey S, Koca C, Tong Z, Gelovani JG, Guha S, Krishnan S, Aggarwal BB. Zyflamend suppresses growth and sensitizes human pancreatic tumors to gemcitabine in an orthotopic mouse model through modulation of multiple targets. Int J Cancer 131(3):E292-303, 2012. e-Pub 2011. PMID: 21935918.
11. Puvanakrishnan P, Diagaradjane P, Kazmi SM, Dunn AK, Krishnan S, Tunnell JW. Narrow band imaging of squamous cell carcinoma tumors using topically delivered anti-EGFR antibody conjugated gold nanorods. Lasers Surg Med 44(4):310-317, 2012. e-Pub 2012. PMID: 22415634.
12. Chatterjee DK, Diagaradjane P, Krishnan S. Nanoparticle-mediated hyperthermia in cancer therapy. Ther Deliv 2(8):1001-1014, 2011. PMID: 22506095.
13. Xie H, Diagaradjane P, Deorukhkar AA, Goins B, Bao A, Phillips WT, Wang Z, Schwartz J, Krishnan S. Integrin a(v)ß(3)-targeted gold nanoshells augment tumor vasculature-specific imaging and therapy. Int J Nanomedicine 6:259-269, 2011. e-Pub 2011. PMID: 21423588.
14. Deorukhkar A, Shentu S, Park HC, Diagaradjane P, Puduvalli V, Aggarwal B, Guha S, Krishnan S. Inhibition of radiation-induced DNA repair and prosurvival pathways contributes to vorinostat-mediated radiosensitization of pancreatic cancer cells. Pancreas 39(8):1277-1283, 2010. PMID: 20531243.
15. Kunnumakkara AB, Sung B, Ravindran J, Diagaradjane P, Deorukhkar A, Dey S, Koca C, Yadav VR, Tong Z, Gelovani JG, Guha S, Krishnan S, Aggarwal BB. {Gamma}-tocotrienol inhibits pancreatic tumors and sensitizes them to gemcitabine treatment by modulating the inflammatory microenvironment. Cancer Res 70(21):8695-8705, 2010. e-Pub 2010. PMID: 20864511.
16. Atkinson RL, Zhang M, Diagaradjane P, Peddibhotla S, Contreras A, Hilsenbeck SG, Woodward WA, Krishnan S, Chang JC, Rosen JM. Thermal enhancement with optically activated gold nanoshells sensitizes breast cancer stem cells to radiation therapy. Sci Transl Med 2(55):55ra79, 2010. PMID: 20980696.
17. Park J, Estrada A, Schwartz JA, Diagaradjane P, Krishnan S, Dunn AK, Tunnell JW. Intra-organ Biodistribution of Gold Nanoparticles Using Intrinsic Two-photon Induced Photoluminescence. Lasers Surg Med 42(7):630-639, 2010. PMID: 21399728.
18. Harikumar KB, Kunnumakkara AB, Sethi G, Diagaradjane P, Anand P, Pandey MK, Gelovani J, Krishnan S, Guha S, Aggarwal BB. Resveratrol, a multitargeted agent, can enhance antitumor activity of gemcitabine in vitro and in orthotopic mouse model of human pancreatic cancer. Int J Cancer 127(2):257-268, 2010. PMID: 19908231.
19. Diagaradjane P, Deorukhkar A, Gelovani JG, Maru DM, Krishnan S. Gadolinium chloride augments tumor-specific imaging of targeted quantum dots in vivo. ACS Nano 4(7):4131-4141, 2010. PMID: 20586481.
20. Harikumar KB, Kunnumakkara AB, Ochi N, Tong Z, Deorukhkar A, Sung B, Kelland L, Jamieson S, Sutherland R, Raynham T, Charles M, Bagherzadeh A, Bagherazadeh A, Foxton C, Boakes A, Farooq M, Maru D, Diagaradjane P, Matsuo Y, Sinnett-Smith J, Gelovani J, Krishnan S, Aggarwal BB, Rozengurt E, Ireson CR, Guha S. A novel small-molecule inhibitor of protein kinase D blocks pancreatic cancer growth in vitro and in vivo. Mol Cancer Ther 9(5):1136-1146, 2010. e-Pub 2010. PMID: 20442301.
21. Krishnan S*, Diagaradjane P*, Cho SH. Nanoparticle-mediated thermal therapy: evolving strategies for prostate cancer therapy. Int J Hyperthermia 26(8):775-789, 2010. e-Pub 2010. PMID: 20858069.
22. Kunnumakkara AB, Diagaradjane P, Anand P, Harikumar KB, Kuzhuvelil HB, Deorukhkar A, Gelovani J, Guha S, Krishnan S, Aggarwal BB. Curcumin sensitizes human colorectal cancer to capecitabine by modulation of cyclin D1, COX-2, MMP-9, VEGF and CXCR4 expression in an orthotopic mouse model. Int J Cancer 125(9):2187-2197, 2009. PMID: 19623659.
23. Puvanakrishnan P, Park J, Diagaradjane P, Schwartz JA, Coleman CL, Gill-Sharp KL, Sang KL, Payne JD, Krishnan S, Tunnell JW. Near-infrared narrow-band imaging of gold/silica nanoshells in tumors. J Biomed Opt 14(2):024044, 2009. PMID: 19405772.
24. Tong Z, Kunnumakkara AB, Wang H, Matsuo Y, Diagaradjane P, Harikumar KB, Ramachandran V, Sung B, Chakraborty A, Bresalier RS, Logsdon C, Aggarwal BB, Krishnan S, Guha S. Neutrophil gelatinase-associated lipocalin: a novel suppressor of invasion and angiogenesis in pancreatic cancer. Cancer Res 68(15):6100-6108, 2008. PMID: 18676832.
25. Diagaradjane P, Shetty A, Wang JC, Elliott AM, Schwartz J, Shentu S, Park HC, Deorukhkar A, Stafford RJ, Cho SH, Tunnell JW, Hazle JD, Krishnan S. Modulation of in vivo tumor radiation response via gold nanoshell-mediated vascular-focused hyperthermia: characterizing an integrated antihypoxic and localized vascular disrupting targeting strategy. Nano Lett 8(5):1492-1500, 2008. e-Pub 2008. PMID: 18412402.
26. Kunnumakkara AB*, Diagaradjane P*, Guha S, Deorukhkar A, Shentu S, Aggarwal BB, Krishnan S. Curcumin sensitizes human colorectal cancer xenografts in nude mice to gamma-radiation by targeting nuclear factor-kappaB-regulated gene products. Clin Cancer Res 14(7):2128-2136, 2008. PMID: 18381954.
27. Verma A, Guha S, Diagaradjane P, Kunnumakkara AB, Sanguino AM, Lopez-Berestein G, Sood AK, Aggarwal BB, Krishnan S, Gelovani JG, Mehta K. Therapeutic significance of elevated tissue transglutaminase expression in pancreatic cancer. Clin Cancer Res 14(8):2476-2483, 2008. PMID: 18413840.
28. Diagaradjane P, Orenstein-Cardona JM, Colón-Casasnovas NE, Deorukhkar A, Shentu S, Kuno N, Schwartz DL, Gelovani JG, Krishnan S. Imaging epidermal growth factor receptor expression in vivo: pharmacokinetic and biodistribution characterization of a bioconjugated quantum dot nanoprobe. Clin Cancer Res 14(3):731-741, 2008. PMID: 18245533.
29. Kunnumakkara AB, Guha S, Krishnan S, Diagaradjane P, Gelovani J, Aggarwal BB. Curcumin potentiates antitumor activity of gemcitabine in an orthotopic model of pancreatic cancer through suppression of proliferation, angiogenesis, and inhibition of nuclear factor-kappaB-regulated gene products. Cancer Res 67(8):3853-3861, 2007. PMID: 17440100.
30. Dai T, Yaseen MA, Diagaradjane P, Chang DW, Anvari B. Comparative study of cryogen spray cooling with R-134a and R-404a: implications for laser treatment of dark human skin. J Biomed Opt 11(4):041116, 2006. PMID: 16965144.
31. Diagaradjane P, Yaseen MA, Yu J, Wong MS, Anvari B. Synchronous fluorescence spectroscopic characterization of DMBA-TPA-induced squamous cell carcinoma in mice. J Biomed Opt 11(1):014012, 2006. PMID: 16526889.
32. Diagaradjane P, Yaseen MA, Yu J, Wong MS, Anvari B. Autofluorescence characterization for the early diagnosis of neoplastic changes in DMBA/TPA-induced mouse skin carcinogenesis. Lasers Surg Med 37(5):382-395, 2005. PMID: 16240416.
33. Dai T, Diagaradjane P, Yaseen MA, Pikkula BM, Thomsen S, Anvari B. Laser-induced thermal injury to dermal blood vessels: analysis of wavelength (585 nm vs. 595 nm), cryogen spray cooling, and wound healing effects. Lasers Surg Med 37(3):210-218, 2005. PMID: 16175632.
34. Parmeswaran D, Pushpan SK, Srinivasan A, Ravi Kumar M, Chandrashekar TK, Ganesan S. In vitro and in vivo investigations on the photodynamic activity of core-modified expanded porphyrin--ammonium salt of 5,10,15,20-tetrakis-(meso-p-sulfonato phenyl)-25,27,29-trithia sapphyrin. Photochem Photobiol 78(5):487-495, 2003. PMID: 14653581.
35. Diagaradjane P, Madhuri S, Aruna P, Gupta PK, Ganesan S. In vivo pharmacokinetics of 8-aminolevulinic acid-induced protoporphyrin IX during pre- and post-photodynamic therapy in 7,12-dimethylbenz(a)nthracene-treated skin carcinogenesis in Swiss mice: a comparison by three-compartment model. Photochem Photobiol 76(1):81-90, 2002. PMID: 12126311.
36. Pushpan SK, Venkatraman S, Anand VG, Sankar J, Parmeswaran D, Ganesan S, Chandrashekar TK. Porphyrins in photodynamic therapy - a search for ideal photosensitizers. Curr Med Chem Anticancer Agents 2(2):187-207, 2002. PMID: 12678743.

Abstracts

1. Diagaradjane P, Briere TM, Beckham T, Li J,Ghia AJ, Han EY. Evaluation of Patient Setup Uncertainties in Brain and Spine Stereotactic Radiosurgery. AAPM 66th Annual Meeting, Los Angeles, CA, 2024.
2. Cifter G, Mackin D, Diagaradjane P, Wand Z, Alfonso CM, Shafiq M, Krafft S, Briere TM. Image registration uncertainty in gammaknife stereotactic radiosurgery. AAPM 66th annual meeting, Los Angeles, CA, 2024.
3. Diagaradjane P, Han EY, Luo D, Ding Y, Kalaitzakis G, Zoros E, Zourari K, Boursianis T, Pappas E, Wen Z, Wang J, Briere TM. PTV marfgins for Gamma Knife Icon frameless treatment: A validation study. Annual Joint AAPM / COMP virtual meeting, 2020.
4. Khoo A, Sahoo N, Krishnan S, Diagaradjane P. Enhancing the relative biological effectiveness of proton therapy using EGFR-targeted gold nanorods. Int J Radiat Oncol Biol Phys 96(2S):S236-S237, 2016.
5. Singh PK, Deorukhkar A, Diagaradjane P, Aziz KE, Tailor RC, Bomalaski J, Krishnan S. Arginine Deiminase Radiosensitizes Pancreatic Cancer by Amplifying Early Endoplasmic Reticulum Stress. Int J Radiat Oncol Biol Phys 96(2S):E588-E589, 2016.
6. Manohar N, Reynoso F, Diagaradjane P, Krishnan S, Cho S. SU-G-IeP3-07: High-Resolution, High-Sensitivity Imaging and Quantification of Intratumoral Distributions of Gold Nanoparticles Using a Benchtop L-Shell XRF Imaging System. Med Phys 43(6):3668, 2016. PMID: 28046374.
7. Khoo A, Sahoo N, Krishnan S, Diagaradjane P. SU-F-T-666: Molecular-Targeted Gold Nanorods Enhances the RBE of Proton Therapy. Med Phys 43(6):3617, 2016. PMID: 28048906.
8. Diagaradjane P, Deorukhkar A, Sankaranarayanapillai M, Manohar N, Singh PK, Goodrich G, Tailor R, Cho S, and Krishnan S. Enhancing the Tumor Specific Radiosensitization Using Molecular Targeted Gold Nanorods. 57th Annual conference of American Association of Physicists in Medicine, Anaheim, CA, 2015.
9. 2. Smith D, Debeb BG, Larson R, Diagaradjane P, and Woodward W. Prophylactic Cranial Irradiation Reduces the Incidence of Brain Metastasis in a Mouse Model of Metastatic Breast Cancer. 57th Annual conference of American Association of Physicists in Medicine, Anaheim, CA, 2015.
10. Debeb BG, Lacerda L, Anfossi S, Diagaradjane P, Chu K, Huo L, Wei C, Larson RA, Wolfe AR, Xu W, Smith DL, Li L, Ivan C, Allen PK, Zhang XH, Calin GA, Krishnamurthy S, Ueno NT, Buchholz TA, Reuben JM, and Woodward WA. MicroRNA 141: A Novel Regulator of Brain Metastasis from Breast Cancer. San Antonio Breast Cancer Symposium, 2014.
11. Singh P, Diagaradjane P, Wolfe T, Lee J, Tailor R, Krishnan S.. Influence of sub-cellular localization and micro-environment on radio-sensitization of cancer cells by conjugated gold nano-particles. Radiation Research Society, Las Vegas, 2014.
12. Debeb BG, Lacerda L, Anfossi S, Diagaradjane P, Chu K, Huo L, Wei C, Larson RA, Wolfe AR, Xu W, Smith DL, Li L, Ivan C, Allen PK, Zhang XH, Calin GA, Krishnamurthy S, Ueno NT, Buchholz TA, Reuben JM, and Woodward WA. MiR-141 is a key regulator of brain metastasis from breast cancer. Brain metases research and emerging therapy conference, Marseille, France, 2014.
13. 3. Manohar N, Reynoso FJ, Diagaradjane P, Krishnan S, Cho SH. Benchtop X-ray Fluorescence Computed Tomography (XFCT) Of A Tumor-bearing Mouse Injected with Gold Nanoparticles: A Postmortem Study. World Molecular Imaging Congress, Seoul, South Korea, 2014.
14. Deorukhkar A, Diep N, Chatterjee DK, Diagaradjane P, Bomalaski J, Krishnan S. Arginine deiminase: A novel radiosensitizer in pancreatic cancer in vitro and in vivo. American Society of Clinical Oncology (ASCO): Gastrointestinal Cancer Symposium, SF, 2014.
15. Agyare E, Diep N, Chatterjee D, Deorukhkar D, Diagaradjane P, Stafford J, Krishnan S. Deep penetrating Triggered Release of Liposomal Nanovehicles loaded Gold Nanoparticles as Radiosensitizers for Pancreatic Cancer Therapy. American Association for Pharmaceutical Scientists annual meeting, San Antonio, TX, 2013.
16. Diagaradjane P, Deorukhkar A, Singh PK, Tailor RC, Diep N, Garden AS, Ang KK, Krishnan S. Radiation response modulation of head and neck cancer using targeted gold nanorods: A preclinical study. Radiation Research Society, New Orleans, LA, 2013.
17. Deorukhkar A, Chung J, Diagaradjane P, Sang K, Diep N, Krishnan S. Sensitizing colorectal cancer to radiation therapy: A unique approach using dietary vitamin E analogue γ-Tocotrienol. Radiation Research Society, New Orleans, LA, 2013.
18. Diagardjane P, Deorukhkar A, Singh PK, Tailor RC, Garden AS, Myres JN, Ang KK, Krishnan S. Radiation response modulation using EGFR targeted gold nanorods. Gordon Research conferences on Cancer Nanotechnology, 2013.
19. Diagaradjane P, Deorukhkar A, Singh PK, Tailor RC, Garden AS, Ang KK, Krishnan S. Modulating the radiation response of Head and neck Cancer cells using EGFR targeted gold nanorods. ASTRO joint workshop on Technology for innovation in Radiation Oncology, 2013.
20. Diagaradjane P, Deorukhkar A, Singh P, Tailor R, Diep N, Garden A, Ang K, Krishnan S. Modulating the Radiation Response of Head and Neck Cancer-A Golden Approach. Annual Radiobiology Retreat, 2013.
21. Deorukhkar A, Chung J, Diagardjane P, Sang K, Diep N, Krishnan S.. Vitamin E analogue γ-Tocotrienol from Palm Oil Sensitizes Colorectal Cancer Cells to Radiation Therapy in vitro and in vivo. . Annual Radiobiology Retreat, 2013.
22. Puvanakrishnan P, Diagaradjane P, Schwartz JA, Krishnan S, Tunnell JW. Targeted gold nanorods as probes for EGFR over-expression in squamous cell carcinoma. Biomedical Engineering Soceity: Biomedical Imaging and Optics, Hartford, CT, 2011.
23. Puvanakrishnan P, Diagaradjane P, Schwartz JA, Krishnan S, Tunnell JW. Real-time near-infrared narrow band imaging of gold nanoparticles in tumors. Advances in Optics for Biotechnology, Medicine and Surgery XII, Naples, Florida, 2011.
24. Puvanakrishnan P, Park J, Diagaradjane P, Schwartz JA, Coleman CL, Gill-Sharp KL, Sang KL, Payne JD, Krishnan S, Tunnell JW. In vivo tumor targeting of gold nanoparticles: Effect of particle type and dosing strategy. American Society for Laser Medicine and Surgery, 2011.
25. Puvanakrishnan P, Diagaradjane P, Schwartz JA, Goodrich GP, Krishnan S, Tunnell JW. Narrow band imaging of targeted gold nanorods in tumors. American Society for Laser Medicine and Surgery, 2011.
26. Krishnan S, Diagaradjane P. Optimizing tumor imaging by bioconjugated QDs via Kupffer cell inactivation. Technical abstracts of the International Symposium on Biomedical Optics-2011 (BiO’S 2011), San Fransisco, California, USA, 2011.
27. Diagaradjane P, Deorukhkar A, Goodrich G, Tunnell JW, Cho S, Krishnan S. Nanoscale actuation of gold nanorods using kilovotage radiation enhances the efficacy of radiation therapy in vivo. Technical abstracts of the International Symposium on Biomedical Optics-2011 (BiO’S 2011), San Fransisco, California, USA, 2011.
28. Deorukhkar A, Ahuja N, Mercado A, Diagaradjane P, Mohindra P, Guha S, Aggarwal B, Krishnan S. Zerumbone, a Sesquiterpene from southeast asian edible ginger sensitizes colorectal cancer cells to radiation therapy. Int J Radiat ONcol Biol Phys 78(3):S654, 2010.
29. Puvanakrishnan P, Park J, Diagaradjane P, Schwartz JA, Coleman CL, Gill-Sharp KL, Sang KL, Payne JD, Krishnan S, Tunnell JW. Wide-field near-infrared narrow bandimaging of gold nanoparticles' distribution in tumors. Biomedical Engineering Society: Biomedical Optics and Imaging, Austin, TX, 2010.
30. Ireson CR, Harikumar KB, Kunnumakkara AB, Deorukhkar A, Tong Z, Maru D, Diagaradjane P, Ochi N, Krishnan S, Aggarwal BB, Rozengurt E, Guha S. A Novel Small Molecule Inhibitor of Protein Kinase D Blocks Pancreatic Cancer Growth Both In Vitro and In Vivo. Gastroenterol 138(5, Suppl 1):S62, 2010.
31. Diagaradjane P, Krishnan S. Significant improvement in radiation therapy outcomes using conjugated gold nanoparticles for nanoscale radiation dose enhancement. Cancer Prevention and Research Institute of Texas Annual Meeting, Austin, Texas, USA, 2010.
32. Papineni RV, Deorukhkar, Diagaradjane P, Orton SP, Vizard D, Wood DO, Krishnan S. Imaging tumor radiotherapy related bone tissue toxicity. Proceedings of World Molecular Imaging Conference, Montreal, Canada, 2009.
33. Papineni RV, Diagaradjane P, Mc Laughlin W, Krishnan S. Non-invasive imaging of radiation induced tumor infiltrating macrophages. Proceedings of World Molecular Imaging Conference, Montreal, Canada, 2009.
34. Park J, Estrada A, Sharp K, Sang K, Schwartz JA, Smith DK, Diagaradjane P, Coleman C, Payne JD, Krishnan S, Korgel BA, Dunn AK, Tunnell JW. Investigation of gold nanoparticles transport kinetics using two-photon induced photoluminescence imaging. Proceedings of the 29th Annual meeting for the American Soceity for Laser Medicine and Surgery, Washington, DC, USA, 2009.
35. Diagaradjane P, Shetty A, Cho S, Tunnel J, Schwartz J, Hazle J, Krishnan S. Enhanced radiation treatment efficacy induced by optically activated gold nanoshell mediated mild hyperthermia: An anti-hypoxic and vascular disrupting effect. Proceedings of the annual meeting of Society for thermal medicine, Tuzon, Arizona, USA, 2009.
36. Atkinson RL, Zhang M, Diagaradjane P, Krishnan S, Rosen JM, Chang J. Hyperthermia sensitizes breast cancer stem cells to radiation therapy. Proceedings of the annual meeting of Society for thermal medicine, Tuzon, Arizona, USA, 2009.
37. Park J, Estrada A, Sharp-Gill K, Sang K, Schwartz J, Smith DK, Diagaradjane P, Krishnan S, Payne D, Tunnell JW. Two-photon induced photoluminescence imaging of gold nanoshell tumor biodistribution. Technical abstracts of the International Symposium on Biomedical Optics-2009 (BiO’S 2009), San Jose, California, USA, 2009.
38. Puvanakrishnan P, Park J, Diagaradjane P, Schwartz J, Colmen C, Sharp-Gill K, Sang K, Payne D, Krishnan S, Tunnell JW. Narrowband imaging of tumors using gold nanoshells. Technical abstracts of the International Symposium on Biomedical Optics-2009 (BiO’S 2009), San Jose, California, USA, 2009.
39. Diagaradjane P, Shetty A, Wang J, Schwartz J, Shentu S, Park HC, Deorukhkar A, Elliot A, Stafford JR, Cho S, Tunnell JW, Hazle J, Krishnan S. Enhanced radiation treatment efficacy induced by optically activated gold nanoshell mediated hyperthermia: An anti-hypoxic and vascular disrupting effect. Proceedings of World Molecular Imaging conference, Nice, France, 2008.
40. Diagaradjane, P, Deorukhkar A, Gelovani J, Krishnan S. Improving molecular imaging tumors by receptor-targeted quantum dots using gadolinium chloride to suppress macrophage activity and increase circulation time. Proceedings of World Molecular Imaging conference, Nice, France, 2008.
41. Diagaradjane, P, Orenstein-Cardona J, Colon N, Deorukhkar A, Gelovani JG, Krishnan S. Compartmental analysis accurately models of kinetics of receptor imaging using conjugated nanoparticles. Proceedings of World Molecular Imaging conference, Nice, France, 2008.
42. Park J, Estrada A, Schwartz J, Diagaradjane P, Krishnan S, Coleman C, Payne D, Tunnell JW. Microscopy of gold nanoshells in tumors using two-photon induced photoluminescence. Proceedings of Laser and Electro-optics society (LEOS) Summer topical meeting, Acapulco, Mexico, 2008.
43. 16. Diagaradjane P, Shetty A, Wang J, Schwartz J, Shentu S, Park HC, Deorukhkar A, Elliot A, Stafford JR, Cho S, Tunnell JW, Hazle J, Krishnan S. Non-invasive hyperthermia using optically activated gold nanoshells sensitizes tumor xenografts to radiation therapy by increasing perfusion and decreasing hypoxia. Technical abstracts of the International Symposium on Biomedical Optics-2008 (BiO’S 2008), San Jose, California, USA, 2008.
44. Diagaradjane P, Orenstein-Cardona J, Colon N, Deorukhkar A, Shentu S, Kuno N, Schwartz DL, Gelovani JG, Krishnan S. EGFR-conjugated near infrared quantum dots as nanoprobes for in-vivo imaging of EGFR expression. Technical abstracts of the International Symposium on Biomedical Optics-2008 (BiO’S 2008), San Jose, California, USA, 2008.
45. Diagaradjane P, Shetty A, Wang J, Schwartz J, Shentu S, Park HC, Deorukhkar A, Elliot A, Stafford JR, Cho S, Tunnell JW, Hazle J, Krishnan S. Modulation of in vivo tumor radiation response via vascular focused hyperthermia – Characterizing gold nanoshells as integrated anti-hypoxic and localized vascular disrupting agent. Proceedings of the American Society for Therapeutic Radiology and Oncology 50th Annual meeting, Int. J. Rad. Oncol. Biol. Phy., 72(1):S64, 2008.
46. Deorukhkar A, Park HC, Shentu S, Diagaradjane P, Krishnan S.. Vorinostat radiosensitizes pancreatic cancers by inhibiting DNA repair and radiation-induced EGFR and NF-κB signaling. Proceedings of 38th Annual meeting of American Pancreatic Association, Chicago, USA, 2007.
47. Guha S, Verma A, Kunnumakkara AB, Diagaradjane P, Krishnan S, Gelovani JG, G. Lopez-Bernstein, Mehta K. Tissue tansglutaminase downregulation potentiates gemcitabine efficacy and blocks pancreatic cancer growth and metastasis in vivo. Proceedings of 38th Annual meeting of American Pancreatic Association, Chicago, USA, 2007.
48. Deorukhkar A, Park HC, Shentu S, Diagaradjane P, Krishnan S. Vorinostat radiosensitizes pancreatic cancers by inhibiting DNA repair and radiation-induced EGFR and NF-κB signaling. Proceedings of ASTRO translational research in radiation oncology and radiology symposium, San Fransisco, USA, 2007.
49. Diagaradjane P, Orenstein-Cardona J, Colon N, Deorukhkar A, Shentu S, Kuno N, Schwartz DL, Gelovani JG, Krishnan S. In vivo imaging of EGFR using EGF-conjugated quantum dot nanoprobes. Proceedings of ASTRO translational research in radiation oncology and radiology symposium, San Fransisco, USA, 2007.
50. Diagaradjane P, Shetty A, Wang J, Schwartz J, Shentu S, Park HC, Deorukhkar A, Elliot A, Stafford JR, Cho S, Tunnell JW, Hazle J, Krishnan S. Non-invasive hyperthermia using optically activated gold nanoshells sensitizes tumor xenografts to radiation therapy by increasing perfusion and decreasing hypoxia. Proceedings of ASTRO translational research in radiation oncology and radiology symposium, San Fransisco, USA, 2007.
51. Diagaradjane P, Orenstein-Cardona J, Colon N, Deorukhkar A, Shentu S, Kuno N, Schwartz DL, Gelovani JG, Krishnan S. In vivo imaging of EGFR using EGF-conjugated quantum dot nanoprobes. Proceedings of the Joint Molecular Imaging Conference, Rhode Island, USA, 2007.
52. Zaman R, Diagaradjane P, Krishnan S, Tunnell JW. Measuring gold nanoparticle concentrations in tissue using diffuse optical spectroscopy. Proceedings of the Conference on Lasers and Electro Optics, Baltimore, MD, USA, 2007.
53. Zaman R, Swartz J, Wang J, Diagaradjane P, Krishnan S, Tunnell JW. Measuring gold nanoparticle concentrations in tissue using diffuse optical spectroscopy. Proceedings of 24th Houston Annual conference on Biomedical Engineering Research, Houston, Texas, USA, 2007.
54. Dai T, Yaseen MA, Diagaradjane P, Chang DW, Anvari B. A comparative study of cryogen spray cooling with R-134A and R-404A: Implications for treatment of dark human skin. Proceedings of the 26th annual meeting of American Society for Lasers in Medicine and Surgery (ASLMS) meeting, Boston, Massachusetts, USA, 2006.
55. Kunnumakkara AB, Guha S, Krishnan S, Diagaradjane P, Gelovani JG, Aggarwal BB. Curcumin potentiates anit-tumor activity of Gemcitabine in an orthotopic model of pancreatic cancer: Role in inhibition of NF-kB of angiogenesis. Proceedings of the 3rd Annual Gastrointestional oncology conference, Arlington, Virginia, USA, 2006.
56. Diagaradjane P, Yaseen MA, Yu J, Wong MS, Anvari B. Autofluorescence characterization for the early diagnosis of neoplastic changes in DMBA/TPA induced mouse skin carcinogenesis. Proceedings of the 25th annual meeting of American Society for Lasers in Medicine and Surgery (ASLMS), Orlando, Florida, USA, 2005.
57. Yaseen MA, Diagaradjane P, Yu J, Wong MS, Anvari B. Combined photochemical and photothermal modalities for laser treatment of hypervascular lesions. Proceedings of 22nd Houston Annual conference on Biomedical Engineering Research, Houston, Texas, USA, 2005.
58. Yaseen MA, Diagaradjane P, Pikkula BM, Yu J, Wong MS, Anvari B. Photothermal and photochemical effects of laser light absorption by indocyanine green (ICG). Technical abstracts of the International Symposium on Biomedical Optics-2005 (BiO’S 2005), San Jose, California, USA, 2005.
59. Diagaradjane P, Yaseen MA, Yu J, Wong MS, Anvari B. Autofluorescence characterization of DMBA-TPA induced two-stage carcinogenesis in mouse skin for the early detection of tissue transformation. Technical abstracts of the International Symposium on Biomedical Optics-2005 (BiO’S 2005), San Jose, California, USA, 2005.
60. Yu J, Diagaradjane P, Yaseen MA, Anvari B, Wong MS. Self-assembled hybrid hollow microspheres as photosensitizer carriers. Proceedings of the Annual American Institute of Chemical Engineers (AICHE) conference, Austin, Texas, USA, 2004.

Book Chapters

1. Jaoude JA, Kouzy R, Diagaradjane P, Taniguchi CM. Management of locally advanced/metastatic disease: Radiation Oncology. In: Pancreatic Cancer: A multidisciplinary Approach. Springer, Cham, 2022.
2. Diagaradjane P, Mohindra P, Krishnan S.. Theranostic applications of gold nanoparticles in cancer. In: Nanoplatform-Based Molecular Imaging. John Wiley & Sons, 639-657, 2010.