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      Richard Y. Wu Image

      Richard Y. Wu, M.S.

      Department of Radiation Physics, Division of Radiation Oncology - Clinical

      Present Title & Affiliation

      Primary Appointment

      Sr. Medical Physicist, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, TX

      Education & Training

      Degree-Granting Education

      1990University of Tennessee, Knoxville, Tennessee, US, Nuclear Engineering (Health Physics option), M.S
      1983Harbin Commerce University, China, US, Electrical Engineering, BS

      Licenses & Certifications

      2002American Board of Radiology, Therapy Physics
      1996American Board of Radiology, Diagnostic Physics
      1994Texas Board of Licensure for Professional Medical
      1993American Board of Science in Nuclear Medicine

      Experience & Service

      Administrative Appointments/Responsibilities

      Sr. Medical Physicist, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, TX, 2003 - Present

      Sr. Medical Physicist, Radiation Physics - Patient Care, The University of Texas MD Anderson Cancer Center, Houston, TX, 2003 - Present

      Medical Physicist, Memorial Hermann Health System, Houston, TX, 2001 - 2003

      Medical Physicist, Forest Park Hospital/Medical Physics Services, Inc, St. Louis, MO, 1999 - 2001

      Medical Physicist, Radiation Safety Officer, Allina Health System, St. Paul, MN, 1995 - 1999

      Instructor, Department of Radiology, Baylor College of Medicine, Houston, TX, 1990 - 1995

      Medical Physicist / Instructor, St. Luke’s Episcopal, Texas Children’s Hospitals, Houston, TX, Houston, TX, 1990 - 1995

      Other Professional Positions

      Scientific Advisor, Davis X-Ray Technology, Inc, United States, 2000

      Professional Memberships

      American Association of Physicist in Medicine

      1991 - Present

      Selected Presentations & Talks

      Formal Peers

      1. 2008. Nuclear cardiology training course, "Radiation Detector and Imaging Equipment". Invited. Houston, TX, US.
      2. 2007. Cardiac Imaging, Nuclear Cardiology License Preparation. Invited. Frederick, MD, US.
      3. 2007. Nuclear cardiology training course, "Introductory Radiation Physics". Invited. Houston, TX, US.
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      Selected Publications

      Peer-Reviewed Articles

      1. Engeseth, GM, Hysing, LB, Yepes, P, Pettersen, HS, Mohan, R, Fuller, C, Stokkevåg, CH, Wu, R, Zhang, X, Frank, SJ, Gunn, GB. Impact of RBE variations on risk estimates of temporal lobe necrosis in patients treated with intensity-modulated proton therapy for head and neck cancer. Acta Oncologica 61(2):215-222, 2022. e-Pub 2022. PMID: 34534047.
      2. Wu RY, Williamson TD, Sahoo N, Nguyen T, Ikner SM, Liu AY, Wisdom PG, Lii M, Hunter RA, Alvarez PE, Gunn GB, Frank SJ, Hojo Y, Zhu XR, Gillin MT. Evaluation of the high definition field of view option of a large-bore computed tomography scanner for radiation therapy simulation. Phys Imaging Radiat Oncol 13:44 - 49, 2020. e-Pub 2020. PMID: 32551371.
      3. Bagley AF, Ye R, Garden AS, Gunn GB, Rosenthal DI, CFuller CD, Morrison WH, Phan J, Sturgis EM, Ferrarotto R, Wu R, Liu AY, Frank SJ. Xerostomia-related quality of life for patients with oropharyngeal carcinoma treated with proton therapy. Radiother Oncol 142:133-139, 2020. e-Pub 2020.
      4. Wu RY, Liu AY, Yang J, Williamson TD, Wisdom PG, Bronk L, Gao S, Grosshan DR, Fuller DC, Gunn GB, Zhu XR, Frank SJ. Evaluation of the accuracy of deformable image registration on MRI with a physical phantom. J Appl Clin Med Phys 1:166-172, 2020. e-Pub 2020.
      5. Wu RY, Liu AY, Yang J, Williamson TD, Wisdom PG, Bronk L, Gao S, Grosshan DR, Fuller DC, Gunn GB, Ronald Zhu X, Frank SJ. Evaluation of the accuracy of deformable image registration on MRI with a physical phantom. J Appl Clin Med Phys 1(1):166-172, 2020. e-Pub 2020. PMID: 31808307.
      6. Moreno AC, Gunther JR, Milgrom S, Fuller CD, Williamson T, Liu A, Wu R, Zhu XR, Dabaja BS, Pinnix CC. Impact of Deep Inspiration Breath Hold on Normal Tissue Sparing with Intensity-Modulated Radiotherapy versus Proton Therapy for Mediastinal Lymphoma. Advances in Radiation Oncology, 2020. e-Pub 2020.
      7. Engeseth GM, Stieb S, Mohamed ASR, Renjie H, Stokkevåg CH, Brydøy M, Fuller CD, Garden AS, Rosenthal DI, Phan J, Morrison WH, Reddy JP, Wu R, Zhang X, Frank SJ, Gunn GB. Outcomes and patterns of radiation associated brain image changes afterproton therapy for head and neck skull base cancers. Radiotherapy and Oncology 151:119=125, 2020. e-Pub 2020.
      8. Wu RY, Liu AY, Williamson DT, Yang J, Wisdom PG, Zhu XR, Frank SJ, Fuller CD, Gunn GB, Gao S. Quantifying the accuracy of deformable image registration for cone‐beam computed tomography with a physical phantom. J Appl Clin Med Phys 10:92 - 100. e-Pub 2019.
      9. Wu RY, Liu AY, Wisdom P, Zhu XR, Frank SJ, Fuller CD, Gunn GB, Palmer MB, Wages CA, Gillin MT, Yang J. Characterization of a new physical phantom for testing rigid and deformable image registration. J Appl Clin Med Phys 20(1):145-153, 2019. e-Pub 2019. PMID: 30580471.
      10. Ng SP, Ludmir EB, Oyervides MA, Wu RY, Frank S, Gunn GB. Combination Intensity Modulated Proton Therapy and Passive Scatter Boost for Rapidly Progressing Nasal Cavity Squamous Cell Carcinoma. Cureus 9(9):e1685, 2017. e-Pub 2017. PMID: 29152442.
      11. Wu RY, Liu AY, Sio TT, Blanchard P, Wages C, Amin MV, Gunn GB, Titt U, Ye R, Suzuki K, Gillin MT, Zhu XR, Mohan R, Frank SJ. Intensity-Modulated Proton Therapy Adaptive Planning for Patients with Oroharyngeal Cancer. International Journal of Particle Therapy 4(2):26-34, 2017. e-Pub 2017.
      12. Blanchard P, Wong AJ, Gunn GB, Garden AS, Mohamed AS, Rosenthal DI, Crutison J, Wu R, Zhang X, Zhu XR, Mohan R, Amin MV, Fuller CD, Frank SJ. Toward a model-based patient selection strategy for proton therapy: External validation of photon-derived normal tissue complication probability models in a head and neck proton therapy cohort. Radiother Oncol 121(3):381-386, 2016. e-Pub 2016. PMID: 27641784.
      13. Suzuki K, Palmer MB, Sahoo N, Zhang X, Poenisch F, Mackin DS, Liu AY, Wu R, Zhu XR, Frank SJ, Gillin MT, Lee AK. Quantitative analysis of treatment process time and throughput capacity for spot scanning proton therapy. Med Phys 43(7):3975, 2016. e-Pub 2016. PMID: 27370116.
      14. You J, Zhao J, Wen X, Wu C, Huang Q, Guan F, Wu R, Liang D, Li C. Chemoradiation therapy using cyclopamine-loaded liquid-lipid nanoparticles and lutetium-177-labeled-core-crosslinked polymeric micelles. J Control Release 15(00081-4):S0168-3659, 2015. e-Pub 2015. PMID: 25637565.
      15. Chang JY, Li H, Zhu XR, Liao Z, Zhao L, Liu A, Li Y, Sahoo N, Poenisch F, Gomez DR, Wu R, Gillin M, Zhang X. Clinical Implementation of Intensity Modulated Proton Therapy for Thoracic Malignancies. Int J Radiat Oncol Biol Phys. e-Pub 2014. PMID: 25260491.
      16. Zhu XR, Poenisch F, Li H, Zhang X, Sahoo N, Wu RY, Li X, Lee AK, Chang EL, Choi S, Pugh T, Frank SJ, Gillin MT, Mahajan A, Grosshans DR. A single-field integrated boost treatment planning technique for spot scanning proton therapy. Radiat Oncol 9:202, 2014. e-Pub 2014. PMID: 25212571.
      17. Liu W, Mohan R, Park P, Liu Z, Li H, Li X, Li Y, Wu R, Sahoo N, Dong L, Zhu XR, Grosshans DR. Dosimetric benefits of robust treatment planning for intensity modulated proton therapy for base-of-skull cancers. Pract Radiat Oncol 4(6):384-91, 2014. e-Pub 2014. PMID: 25407859.
      18. Mackin D, Li Y, Taylor MB, Kerr M, Holmes C, Sahoo N, Poenisch F, Li H, Lii J, Amos R, Wu R, Suzuki K, Gillin MT, Zhu XR, Zhang X. Improving spot-scanning proton therapy patient specific quality assurance with HPlusQA, a second-check dose calculation engine. Med Phys 40(12):121708, 2013. e-Pub 2013. PMID: 24320494.
      19. Quan EM, Liu W, Wu RY, Li Y, Frank SJ, Zhang X, Zhu XR, Mohan R. Preliminary evaluation of multifield and single-field optimization for the treatment planning of spot-scanning proton therapy of head and neck cancer. Med Phys 40(8):081709, 2013. e-Pub 2013. PMID: 23927306.
      20. Kandula S, Zhu X, Garden AS, Gillin M, Rosenthal DI, Ang KK, Mohan R, Amin MV, Garcia JA, Wu R, Sahoo N, Frank SJ. Spot-scanning beam proton therapy vs intensity-modulated radiation therapy for ipsilateral head and neck malignancies: a treatment planning comparison. Med Dosim 38(4):390-4, 2013. e-Pub 2013. PMID: 23916884.
      21. Sahoo N, Zhu XR, Arjomandy B, Ciangaru G, Lii M, Amos R, Wu R, Gillin MT. A procedure for calculation of monitor units for passively scattered proton radiotherapy beams. Med Phys 35(11):5088-97, 2008. e-Pub 2008. PMID: 19070243.
      22. Zullo JR, Kudchadker R, Wu R, Lee A, Prado K. Implication of CT Table Sag on Geometrical Accuracy During Virtual Simulation. Med Dosim 32(4):233-6, 2007. e-Pub 2007. PMID: 17980822.
      23. Murphy P, Wu Y, Glaze S. Attenuation properties of lead composite aprons. Radiology 186 269:272, 1993. e-Pub 1993.

      Review Articles

      1. Sahoo N, Poenisch F, Zhang X, Li Y, Lii M, Li H, Gautam AS, Wu RY Gillin M, Zhu XR. 3D treatment planning system-Varian Eclipse for proton therapy planning. Med Dosim 43(2):184-194, 2018. e-Pub 2018. PMID: 29753334.
      2. Arjomandy B, Sahoo N, Zhu XR, Zullo JR, Wu RY, Zhu M, Ding X, Martin C, Ciangaru G, Gillin MT. An overview of the comprehensive proton therapy machine quality assurance procedures implemented at The University of Texas M. D. Anderson Cancer Center Proton Therapy Center-Houston. Med Phys 36(6):2269-82, 2009. e-Pub 2009. PMID: 19610316.

      Abstracts

      1. Wu R, Hunter R, Liu A, Amin M, Blanchard P, Zhu X. Dosimetry Analysis On Proton Treatment Plan Using CT Images with Automatic Metal Artifact Reduction. 59th Annual AAPM Meeting, Denver, CO, July 30-August 3, 2017, 2017. e-Pub 2017.
      2. Wu R, Crowford C, Georges R, Liu A, Amin M, Sio T, Gunn B, Poenisch F, Palmer M, Gillin M, Frank S, Zhu X. SU-F-T-195: Systematic Constraining of Contralateral Parotid Gland Led to Iproe Dosimetri Outcomes for Multi-Field Optimiztion with Scanning Beam Proton Therapy: Promising Results From a Pilot Study in Patients with Base of Tongue Carcinoma. Med Phys 43(6):3506-3507, 2016. e-Pub 2016. PMID: 28048650.
      3. Wu R, Martin C, Liu A, Suzuki K, Gillin M, Zhu R. A Modified Methodology to Accurately Validate CT Number Constancy for Proton Therapy, 2015. e-Pub 2015.
      4. Sahoo N, Dhanesar S, Poenisch F, Lii M, Li H, Zhang X, Amos R, Wu R, Gillin M, Zhu X. Application of a Semi-empirical Formula to Determine Spread Out Bragg Peak Factors and Range Shifter Factors From Measured Depth Dose Curves for Passively Scattered Proton Beams. Medical Physics 40(6):SU-E-T-04, 2013. e-Pub 2013.
      5. Mackin D, Zhang X, Li Y, Taylor M, Kerr M, Holmes C, Sahoo N, Poensich F, Li H, Lii M, Amos R, Wu R, Suzuki K, Gillin M, Zhu X. Improving Spot Scanning Proton Therapy Patient-Specific Quality Assurance Through Early Application of Second-Check Dose Calculation Software. Medical Physics 40(6):SU-E-T-157, 2013. e-Pub 2013.
      6. Hojo Y, Gillin M, Suzuki K, Wu R, Zhu X. 3D Collision Viewer for Proton Therapy Treatment Planning. Medical Physics 40(6):SU-E-T-251, 2013. e-Pub 2013.
      7. Dhanesar S, Sahoo N, Kerr M, Taylor M, Summers P, Alvarez P, Wu R, Poenisch F, Zhu X, Gillin M. Intensity Modulated Proton Therapy Plans with Multiple Fields for Prostate Cancer. Medical Physics 40(6):SU-E-T-403, 2013. e-Pub 2013.
      8. Wu RY, Wisdom P, Sahoo N, Lii M, Lee AK, Gillin MT, Zhu M. A novel universal nozzle collimator for X-ray imaging during proton treatment. 51st PTCOG Annual Meeting, Seoul, South Korea, May 14-19, 2012, 2012. e-Pub 2012.
      9. Quan E, Liu W, Li Y, Zhang X, Zhu X, Mohan R, Wu R. Improvement in robustness and delivery efficiency of intensity-modulated proton therapy using single-field optimization with energy absorber. 54th Annual AAPM Meeting, Charlotte, NC, July 29-August 2, 2012, 2012. e-Pub 2012.
      10. Song X, Wu R, Poenisch F, Zhu XR, Sahoo N, Gillin M. The effect of planning CT image noise level on the calculated proton beam range and dose uncertainty. 50th Annual PTCOG, Philadelphia, PA, May 12-14, 2011, 2011. e-Pub 2011.
      11. Song X, Wu R, Sahoo N, Poenisch F, Zhu XR, Gillin M. The effect of planning CT images noise level on the calculated proton beam range and dose uncertainty. 50th Annual PTCOG Meeting, 2010. e-Pub 2010.
      12. Li H, Liu R, Wu R, Sahoo N, Mohan R, Gillin M, Zhu XR. Effect of Ct calibration phantom size on the range in proton radiation therapy. 50th AAPM Annual Meeting, 2008. e-Pub 2008.
      13. Arjomandy B, Sahoo N, Zhu XR, Zullo J, Wu R, Zhu M, Ding X, Gillin M. An overview of comprehensive proton machine quality assurance at UTMD Anderson Cancer Center. 50th AAPM Annual Meeting, 2008. e-Pub 2008.
      14. Wu R, Amos R, Sahoo N, Kornguth D, Bluett J, Gillin M, Zhu XR. Effect of CT truncation artifacts toproton dose calculation. 50th AAPM Annual Meeting, 2008. e-Pub 2008.
      15. Wu R, Zhang X, Amos R, Prado K, Lii M, Sahoo N, Gillin M, Zhu XR. Evaluation of titanium metal imaging artifacts on proton dose calculation. 49th AAPM Annual Meeting, 2007. e-Pub 2007.
      16. Liu R, Prado K, Wu R, Stevens D, Pan T, Cody D. Optimal CT imaging protocol settings for CT simulators. 49th AAPM Annual Meeting, 2007. e-Pub 2007.
      17. Liu R, Prado K, Wu R, Stevens D, Pan T, Cody D. Optimal CT Imaging Protocol Settings for CT Simulators, 2007. e-Pub 2007.
      18. Liu R, Prado K, Wu R, Balter P. A CT Daily Quality Assurance On-Couch Procedure and Phantom in Radiation Oncology, 2007. e-Pub 2007.
      19. Sahoo N, Zhu X, Lii M, Amos R, Arjomandy B, Wu R, Gillin M. Study of Dose Distribution in Passively Scattered Proton Beams for Small Field Sizes, 2007. e-Pub 2007.
      20. Zhu XR, Zhang L, Kudchadker R, Wu R, Balter P, Mohan R, Gillin M, Dong L. Clinical Implementation of Cone-Beam CT for Image-Guide Radiation Therapy, 2006. e-Pub 2006.
      21. Liengsawangwong P, Kudchadker R, Wu RY, Session R, Diel T, Aleman G, Dong L, Gillin M, Zhu X. Mechanical Radiation and Imaging Isocenter Quantification on Four Varian On-Board Imager Clinacs, 2006. e-Pub 2006.
      22. Zullo J, Kudchadker, Wu RY, Lee A, Prado K. Implication of CT Couch Sag on Geometrical Accuracy During Virtual Simulation, 2006. e-Pub 2006.
      23. Lindsay P, Zhu X, Zhang L, Wu R, Kudchadker R, Salehpour M, Liu R, Mohan R, Gillin M, Dong L. Effect of measured cone-beam CT-density calibration on dose calculations. 48th AAPM Annual Meeting, July 31st-August 3rd, 2006. e-Pub 2006.
      24. Wu R, Dong L, Tung S, Gillin M. Accuracy of CT Numbers and Its Effect On Dose Calculations. 47th AAPM Annual Meeting, July 23-29, 2005, 2005. e-Pub 2005.

      Book Chapters

      1. Sahoo N, Gautam AS, Poenisch F, Zhu XR, Li H, Zhang X, Wu R, Beddar S, and Gillin MT. In vivo Dosimetry for proton therapy. In: Principles and Practices of Proton Beam Therapy, 795-817, 2015.

      Patents

      1. “Device and Method for Evaluation of Deformable Image Registration (DIR) System”. Patent Number: UTSC.P1357US.
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      CV information above last modified July 22, 2026

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