Roi Weiser, M.D.
Department of Surgical Oncology, Division of Surgery
Present Title & Affiliation
Primary Appointment
Assistant Professor, Department of Surgical Oncology, Division of Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX
Dual/Joint/Adjunct Appointment
Associate Program Director, Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas
Assistant Professor, Department of Breast Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX
Assistant Professor, Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX
Education & Training
Degree-Granting Education
| 2011 | Tel-Aviv University, Tel-Aviv, IL, MD |
| 2006 | Tel-Aviv University, Tel-Aviv, IL, Health Sciences, BS |
| 2004 | Université Paris IV, La Sorbonne, FR, Maîtrise de Philosophie, MA |
| 2003 | Université Paris III, Sorbonne Nouvelle, FR, Diplôme Universitaire de Langue Française, Diploma |
| 2002 | Tel-Aviv University, Tel-Aviv, IL, Philosophy and English Literature, BA |
Postgraduate Training
| 2022-2022 | MD Anderson Robotic D2 Gastrectomy Course, IGCC 2022 Pre-Congress Hands-On Course, Houston, Texas |
| 2021-2022 | Clinical Fellowship, Surgical Oncology (International program), University of Texas MD Anderson Cancer Center, Houston, Texas |
| 2020-2020 | Clinical Trials Design Course for Fellows, University of Texas MD Anderson Cancer Center, Houston, Texas |
| 2020-2021 | Clinical Fellowship, Breast Surgical Oncology, University of Texas Medical Branch, Galveston, Texas |
| 2020-2020 | Oncoplastic Breast Surgery Course, American Society of Breast Surgery, University of Texas Medical Branch, Galveston, Texas |
| 2018-2019 | Advanced Teaching Strategies GME program, Tel-Aviv University, Tel-Aviv |
| 2016-2018 | Chief Resident, General Surgery, Tel-Aviv Sourasky Medical Center, Tel-Aviv |
| 2012-2018 | Clinical Residency, General Surgery, Tel-Aviv Sourasky Medical Center, Tel-Aviv |
| 2010-2011 | Clinical Internship, Tel-Aviv Sourasky Medical Center, Tel-Aviv |
Board Certifications
| 2018 | Israeli Board Certification in General Surgery |
Experience & Service
Academic Appointments
Faculty, Tel-Aviv Sourasky Medical Center, Tel-Aviv, 2018 - 2020
Other Appointments/Responsibilities
Lieutenant (Reserve Duty), Heliborne Search and Rescue Unit, Israeli Defense Force, 2014 - Present
Sergeant Major, Israeli Defense Force, 1994 - 1997
Institutional Committee Activities
Member, Institutional Algorithms for Peri-op Management of Anticoagulation and Antiplatelet Agents Working Group, 2024 - Present
Member, Education Executive Team, 2024 - Present
Member, Institutional Committee on Emergency Department Reorganization, 2019 - 2020
Member, Institutional Committee on Nutritional Intervention, 2018 - 2020
Data Science and Quality Division, Institutional Committee on Artificial Intelligence and Physician Decision Support, 2018 - 2020
Professional Memberships
Selected Publications
Peer-Reviewed Articles
- Keatts SA, Salem AF, Swanson DM, Farooqi AS, Bishop AJ, Amaria RN, McQuade JL, Glitza IC, Diab A, Weiser R, et al. Durable Local Control with Hypofractionated Radiation Therapy for Unresectable or Metastatic Melanoma. Clin Transl Radiat Oncol 49(100856), 2024. PMID: 29208633.
- Wanis KN, Kuerer HM, Sun SX, Hunt KK, Glencer AC, Teshome M, Lucci A, Weiser R, Johnson H, Smith BD, Gutierrez AM, Shaitelman SF, Arun BK. Clinical Outcomes for BRCA Pathogenic Variant Carriers With Breast Cancer Undergoing Breast Conservation. JAMA Netw Open 7(6):e2418486, 2024. e-Pub 2024. PMID: 38916888.
- Jacques SK, McKeown J, Grover P, Johnson DB, Zaremba A, Dimitriou F, Weiser R, Farid M, Namikawa K, Sullivan RJ, Rutkowski P, Lebbe C, Hamid O, Zager JS, Michielin O, Neyns B, Nakamura Y, Robert C, Mehnert J, Ascierto PA, Bhave P, Park B, Zimmer L, Mangana J, Mooradian M, Placzke J, Allayous C, Glitza Oliva IC, Mehmi I, Depalo D, Wicky A, Schwarze JK, Roy S, Boatwright C, Vanella V, Long GV, Menzies AM, Lo SN, Carlino MS. Outcomes of Patients with Resected Stage III/IV Acral or Mucosal Melanoma, Treated with Adjuvant Anti-PD-1 Based Therapy. Eur J Cancer 199:113563, 2024. e-Pub 2024. PMID: 38278007.
- Halfteck GG, Polychronopoulou YE, Haque W, Weiser R, Hatch SS, Klimberg VS. De-escalation of Post-mastectomy Irradiation in Hormone Receptor-Positive Breast Cancer with One to Three Positive Nodes. Ann Surg Oncol 30(13):8335-8343, 2023. e-Pub 2023. PMID: 37679538.
- Weiser R, Manno GC, Cass SH, et al. Fluoroscopic Intra-operative Breast Neoplasm and Node Detection (FIND). J Am Coll Surg 236(4):575-585, 2023. e-Pub 2023.
- Ho JJ, Mattei J, Tetzlaff M, Williams MD, Davies MA, Diab A, Oliva ICG, McQuade J, Patel SP, Tawbi H, Wong MK, Fisher SB, Hanna E, Keung EZ, Ross M, Weiser R, et al. Neoadjuvant Checkpoint Inhibitor Immunotherapy for Resectable Mucosal Melanoma. Front Oncol:1001150, 2022. e-Pub 2022.
- Weiser R, Polychronopoulou E, Hatch SS, Haque W, Ghani HA, He J, Kuo YF, Gradishar WJ, Klimberg VS. Adjuvant Chemotherapy in Patients with Invasive Lobular Carcinoma and Use of the 21-gene Recurrence Score: A National Cancer Database Analysis. Cancer 128(9):1738-1747, 2022. e-Pub 2022. PMID: 35137951.
- Gavert N, Zwang Y, Weiser R, et al. Ex Vivo Organotypic Cultures for Synergistic Therapy Prioritization Identify Patient-specific Responses to Combined MEK and Src Inhibition in Colorectal Cancer. Nat Cancer 3(2):219-231, 2022. e-Pub 2022.
- Newcomer K, Robbins K, Perone J, Hinojosa FL, Chen D, Jones S, Kaufman C, Weiser R, Fields R, Tyler D. Malignant Melanoma: Evolving Practice Management in an Era of Increasingly Effective Systemic Therapies. Curr Probl Surg 59(1):101030, 2022. e-Pub 2022.
- Weiser R, Polychronopoulou E, Haque W, et al. Prognosis and Chemotherapy Use in Breast Cancer Patients with Multiple Lymphatic Micrometastases: an NCDB Analysis. Ann Surg Oncol 28(13):8717-8727, 2021. e-Pub 2021.
- Weiser R. Klimberg VS. ASO Author Reflections: Breast Cancer: What is in a Positive Node?. Ann Surg Oncol 28(13):8728, 2021. e-Pub 2021.
- Menes TS, Golan O, Weiser R, Tvito Green R. ASO Author Reflections: Facing the Challenge of the Missing clip in Breast Lumpectomy Specimens. Ann Surg Oncol 28(9):4981-4982, 2021. e-Pub 2021.
- Green RT, Weiser R, Golan O, Menes TS. In Search of the Lost Clip: Outcome of Women after Needle Guided Lumpectomy of a Marking Clip. Ann Surg Oncol 28(9):4974-4980, 2021. e-Pub 2021.
- Weiser R, Polychronopoulou E, Kuo YF, et al. De-escalation of Endocrine Therapy in Early Hormone Receptor-Positive Breast Cancer: When is Local Treatment Enough?. Ann Surg 274(4):654-663, 2021. e-Pub 2021.
- Weiser R, Haque W, Polychronopoulou E, et al. The 21-Gene Recurrence Score in Node-Positive, Hormone Receptor-Positive, HER2-Negative Breast Cancer: A Cautionary Tale from an NCDB Analysis. Breast Cancer Res Treat 185(3):667-676, 2021. e-Pub 2021.
- Pencovich N, Nevo N, Weiser R, et al. Postoperative Rise of Circulating Mitochondrial DNA is Associated with Inflammatory Response in Patients Following Pancreaticoduodenectomy. Eur Surg Res 62(1):18-24, 2021. e-Pub 2021.
- Nejman D, Livyatan I, Fuks G, Gavert N, Zwang Y, Geller LT, Rotter-Maskowitz A, Weiser R, et al. The Human Tumor Microbiome Is Composed of Tumor Type-Specific Intracellular Bacteria. Science 368(6494):973-980, 2020. e-Pub 2020.
- Weiser R, Pencovich N, Mlynarsky L, et al. Management of Endoscopic Retrograde Cholangiopancreatography – Related Perforations: Experience of a Tertiary Center. Surgery 161(4):920-929, 2017. e-Pub 2017.
- Papoulas M, Weiser R, Rosen G, et al. Visceral Fat Content Correlates with Retroperitoneal Soft Tissue Sarcoma (STS) Local Recurrence and Survival. World J Surg 39(8):1895-901, 2015. e-Pub 2015.
- Levy T, Weiser R, Boaz M, et al. The significance of the pattern of serum CA125 level ascent to above the normal range in epithelial ovarian, primary peritoneal and tubal carcinoma patients. Gynecol Oncol 129(1):165-8, 2013. e-Pub 2013.
- Levy T, Weiser R, Boaz M, et al. Prognostic significance of rising serum CA-125 levels within the normal range in patients with epithelial ovarian, primary peritoneal and tubal cancers, who, after initial treatment, had a complete clinical response. Int J Gynecol Cancer(8):1344-8, 2012. e-Pub 2012.
Other Articles
- Seldomridge, Weiser R, Holder . Systemic Therapy for Melanoma: What Surgeons Need to Know.
Book Chapters
- Weiser R, Lymphatic Mapping KV, Lymphadenectomy S. In: Cameron JL and Cameron AM (eds.). Current Surgical Therapy, 14th edition, 2023.
- Weiser R, Berman RS, Gershenwald. Wide Excision of Primary Cutaneous Melanoma. In: In: Sabel MS, Mulholland MW (eds.). 2nd Edititon, 2023.
- Weiser R, Spiquel L, Singhal D, Klimberg VS. Lymphedema Prevention and Treatment: Axillary Reverse Mapping, LYMPHA, and Lympho Node Transfer. In: In: Bland KI, Copeland EM, Klimberg VS, Gradishar WJ (eds.). 6th Edition. The Breast, 2023.
- Weiser R, You. Surgical Principals. In: Foote: Gunderson and Tepper's Clinical Radiation Oncology. 6th Edtion.
- Weiser R, Klimberg VS, Hunt KK. Diseases of the Breast. In: Tyler’s Sabiston Textbook of Surgery. 22nd edition.
- Weiser R, Klimberg VS. In: In: Chu QD, Klimberg VS, Anderson B, Balch C, Parker C, Dedey F, Mendez J, and Are C (eds.). A Practical Guide to Managing Breast Cancer for Low-Middle Income Countries.
Letters to the Editor
- Weiser R, Polychronopoulou E, Klimberg VS. Reply to “the use of national datasets to evaluate outcomes for invasive lobular carcinoma. Cancer 128: 3418-3419, 2022.
Selected Presentations & Talks
Local Presentations
- 2024. Multidisciplinary Care Discussion Panel. Invited. Cancer Network Melanoma Integration Retreat. Houston, Texas, US.
- 2024. Immunotherapy for Breast Cancer and Perioperative Considerations. Conference. Immunotherapy for Breast Cancer and Perioperative Considerations. Houston, TX, US.
- 2023. Multidisciplinary Care Discussion Panel. Invited. Multidisciplinary Care Discussion Panel. Houston, TX, US.
- 2021. Fluoroscopic Intra-operative Neoplasm and Node Detection (FIND): a Quality Improvement Comparative Trial with Wire Localization Poster Presentation (Presenter). Poster. UTMB Health Graduate Medical Education Quality Improvement & Patient Safety Poster Session. Galveston, Texas, US.
Regional Presentations
- 2024. Regional Skills Course on Breast. Visiting. L-Star Galveston ACS Regional Oncoplastic Breast Course Visiting professorship (Faculty). Galveston, Texas, US.
- 2022. Efficacy of Fluoroscopic Intraoperative Neoplasm and Node Detection (FIND) Procedure Compared to Standard Wire Localization. Conference. Houston, Texas, US.
- 2021. The 21-gene Recurrence Score and Chemotherapy Use in Node Positive Invasive Lobular Carcinoma Patients: An NCDB Analysis. Conference. The 21-gene Recurrence Score and Chemotherapy Use in Node Positive Invasive Lobular Carcinoma Patients: An NCDB Analysis, TX, US.
National Presentations
- 2025. Neoadjuvant Clinical Stage II Trial. Poster. Chicago, IL, US.
- 2025. Real-world outcomes of patients with clinically node positive melanoma undergoing neoadjuvant immunotherapy and nodal dissection. Poster. Tampa, Florida, US.
- 2025. Nodal imaging concordance with pathologic findings after neoadjuvant immunotherapy in patients with Stage III melanoma. Poster. Tampa, Flordia, US.
- 2024. Combination Radiotherapy and Immunotherapy for Patients Presenting with Locoregionally Advanced Anorectal Mucosal Melanoma. Poster. New Orleans, Louisiana, US.
- 2024. Delineating germline, molecular and microbiome factors driving mucosal melanoma risk and immunotherapy response. Poster. New Orleans, Louisiana, US.
- 2024. Adrenal Insufficiency in the Immunotherapy Era – Improving the Identification of At-Risk Patients Prior to Melanoma Surgery. Poster. Adrenal Insufficiency in the Immunotherapy Era – Improving the Identification of At-Risk Patients Prior to Melanoma Surgery. Altanta, GA, US.
- 2024. Avoiding Perioperative Adrenal Crisis. Invited. Steamboat Springs, Colorado, US.
- 2022. Intraoperative Fluoroscopy Obviates the Need for Second Procedure for Breast Lesion Localization. Oral Presentation. Conference. Intraoperative Fluoroscopy Obviates the Need for Second Procedure for Breast Lesion Localization. Oral Presentation. Palm Beach, FL, US.
- 2021. Fluoroscopic Intra-operative Neoplasm and Node Detection (FIND): A Comparative Trial with Needle Localization. Poster. Fluoroscopic Intra-operative Neoplasm and Node Detection (FIND): A Comparative Trial with Needle Localization, US.
- 2021. De-escalation of Endocrine Therapy in Early Hormone Receptor-Positive Breast Cancer: When is Local Treatment Enough? Oral Presentation. Conference. De-escalation of Endocrine Therapy in Early Hormone Receptor-Positive Breast Cancer: When is Local Treatment Enough? Oral Presentation, US.
- 2021. Prognosis and Chemotherapy Use in Breast Cancer Patients with Single and Multiple Lymphatic Micrometastases: An NCDB Analysis. Conference, US.
- 2021. Lobular Cancer Responsiveness to Chemotherapy is Equivalent to Ductal Cancer with Similar Genomic Profiles: An NCDB Analysis. Poster. Lobular Cancer Responsiveness to Chemotherapy is Equivalent to Ductal Cancer with Similar Genomic Profiles: An NCDB Analysis, US.
- 2020. Characterizing the Breast Cancer Microbiome. Conference, US.
- 2016. Lymph Node Status and Patterns of Recurrence Following Pancreaticoduodenectomy for Pancreatic Ductal Adenocarcinoma. Poster. Lymph Node Status and Patterns of Recurrence Following Pancreaticoduodenectomy for Pancreatic Ductal Adenocarcinoma. Boston, MA, US.
International Presentations
- 2025. Debate III: Do we need to re-operate all positive margins after BCS? – In favor. Invited. Jerusalem, IL.
- 2024. Combination TVEC and Immune Checkpoint Blockade in the Neoadjuvant Setting in Patients with Metastatic Melanoma. Poster. Australasian Melanoma Conference. Sydney, AU.
- 2024. Combination Radiotherapy and Immunotherapy for Patients Presenting with Locoregionally Advanced Anorectal Mucosal Melanoma. Conference. Australasian Melanoma Conference. Sydney, AU.
- 2022. Completion Lymphadenectomy in Melanoma. Invited. Completion Lymphadenectomy in Melanoma, IL.
- 2019. Exploring Novel Combinatorial Treatments for Colorectal Cancer Using an Ex-vivo Organ Culture Method. Oral Presentation. Conference. Exploring Novel Combinatorial Treatments for Colorectal Cancer Using an Ex-vivo Organ Culture Method. Oral Presentation, IL.
- 2018. Adnexal Carcinomas: Experience of a Tertiary Center. Poster. Barcelona, ES.
- 2017. Adnexal Carcinomas: Experience of a Tertiary Center. Oral Presentation. Conference. Adnexal Carcinomas: Experience of a Tertiary Center. Oral Presentation, IL.
- 2016. Lymph Node Status and Patterns of Recurrence Following Pancreaticoduodenectomy for Pancreatic Ductal Adenocarcinoma. Conference. Lymph Node Status and Patterns of Recurrence Following Pancreaticoduodenectomy for Pancreatic Ductal Adenocarcinoma, IL.
- 2015. Management of Endoscopic Retrograde Cholangiopancreatography Related Perforations. Conference. Management of Endoscopic Retrograde Cholangiopancreatography Related Perforations, IL.
- 2013. Surveillance of Hepatocellular Carcinoma in Israel. Conference. Surveillance of Hepatocellular Carcinoma in Israel, IL.
- 2012. The Prognostic Significance of Rising Serum CA-125 Levels within the Normal Range in Patients with Epithelial Ovarian, Tubal and Primary Peritoneal Carcinoma after Complete Clinical Response to Primary Therapy. Poster. Tel Aviv, IL.
Formal Peers
- 2023. Fluoroscopic Intraoperative Neoplasm and Node Detection. Visiting. Fluoroscopic Intraoperative Neoplasm and Node Detection, US.
Grant & Contract Support
| Date: | 2025 - 2026 |
| Title: | Evaluating the Nodal Basin of Patients with Melanoma Treated in the Neoadjuvant Arm of SWOG S1801 to Identify Predictors of Prognosis and Response |
| Funding Source: | SWOG/Hope Foundation Impact Award |
| Role: | PI |
Patient Reviews
CV information above last modified March 26, 2025