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      Sajad Khazal Image

      Sajad Khazal, MBBCH

      Department of Pediatrics, Division of Pediatrics

      Present Title & Affiliation

      Primary Appointment

      Medical Director, Pediatrics - Patient Care, Immune Effector Cell Program, The University of Texas MD Anderson Cancer Center, Houston, Texas

      Associate Professor, Pediatrics-Patient Care, The University of Texas MD Anderson Cancer Center, Houston, TX

      Education & Training

      Degree-Granting Education

      2002College of Medicine/University of Baghdad, Baghdad, IQ, Bachelor of Medicine and Surgery, M.B.Ch.B

      Postgraduate Training

      2012-2015Clinical Fellowship, Pediatric Hematology and Oncology, Children’s Hospital Los Angeles, Los Angeles, California
      2011-2012Chief Resident, Pediatrics, The Brooklyn Hospital Center, Brooklyn, New York
      2009-2011Clinical Residency, General Pediatrics - Chief Resident, The Brooklyn Hospital Center, Brooklyn, New York
      2008-2009Clinical Internship, General Pediatrics, The Brooklyn Hospital Center, Brooklyn, New York
      2004-2006Clinical Residency, Department of Urology, College of Medicine/University of Baghdad/Medical City/Surgical Subspecialties Hospital, Baghdad
      2002-2004Clinical Internship, Al-Yarmouk Teaching Hospital, Baghdad

      Licenses & Certifications

      2017The American Board of Pediatric Hematology Oncology
      2017Texas Medical License
      2011The American Board of Pediatrics
      2011California Medical License
      2011New York Medical License
      2011Connecticut Medical License

      Experience & Service

      Faculty Academic Appointments

      Associate Professor, Division of Transplant, Cell Therapy, and Hematologic Malignancies, Transplant, Cell Therapy, and Hematologic Malignancies, Loma Linda University Health and School of Medicine, Loma Linda, California, 2023 - 2025

      Associate Professor, Pediatrics Patient Care, Pediatrics, The University of Texas MD Anderson Cancer Center, Houston, TX, 2022 - 2023

      Assistant Professor, Pediatrics Patient Care, The University of Texas MD Anderson Cancer Center, Houston, TX, 2017 - 2022

      Assistant Professor, Pediatric Marrow and Blood Cell Transplantation Program, Albert Einstein College of Medicine of Yeshiva University Children’s Hospital at Montefiore, Bronx, NY, 2015 - 2017

      Administrative Appointments/Responsibilities

      Medical Director, Pediatrics Patient Care, The University of Texas MD Anderson Cancer Center, Houston, TX, 2023 - 2023

      Fellowship Program Director, Pediatrics Stem Cell Transplantation and Cellular Therapy, The University of Texas MD Anderson Cancer Center, Houston, TX, 2021 - 2023

      Chief Pediatric Hematology Oncology Fellow, Pediatrics, Children's Hospital Los Angeles, Los Angeles, CA, 2014 - 2015

      Extramural Institutional Committee Activities

      Member, Member of Institutional Review Board, Loma Linda University Medical Center, 2024 - 2025

      Member of the Safety 365 Operational Priorities Taskforce, The University of Texas MD Anderson Cancer Center, The University of Texas MD Anderson Cancer Center, 2019 - 2020

      Member, Pediatric Clinical Practice Committee, The University of Texas MD Anderson Cancer Center, 2018 - 2023

      Member of Focus on Junior Faculty Committee, The University of Texas MD Anderson Cancer Center, The University of Texas MD Anderson Cancer Center, 2017 - 2022

      Member of CARTOX Audit Committee, The University of Texas MD Anderson Cancer Center, The University of Texas MD Anderson Cancer Center, 2017 - 2020

      Editorial Activities

      Journal Reviewer, Journal of eClinicalMedicine, 2023 - Present

      Journal Reviewer, Journal of Clinical Medicine, 2021 - Present

      Journal Reviewer, Expert Opinion On Pharmacology, 2021 - Present

      Review Editor, Frontiers in Pediatrics/Pediatric Hematology and Hematologic Malignancies, 2020 - Present

      Journal Reviewer, Frontiers in Oncology, 2020 - Present

      Journal Reviewer, Frontiers in Pediatrics, 2020 - Present

      Journal Reviewer, Cancers, 2020 - Present

      Honors & Awards

      2023Distinguished Faculty Award, Loma Linda University Medical Center
      2022President's Recognition of Faculty Excellence in Education and Mentorship Advancement, MD Anderson Cancer Center
      2010Best Resident as a Teacher, The Brooklyn Hospital Center
      2009Resident of the Year, The Brooklyn Hospital Center
      2009Best Resident as a Teacher, The Brooklyn Hospital Center
      2003College Prize, Honor Student, College of Medicine, University of Baghdad

      Professional Memberships

      American Society of Pediatric Hematology Oncology

      2021

      American Society of Pediatric Hematology Oncology (ASPHO) Board Review Course Committee

      2017 - Present

      Foundation for Accreditation of Cellular Therapy (FACT)

      2016 - Present

      American Society of Transplant and Cellular Therapy

      2015 - Present

      American Society of Hematology

      2012 - Present

      Children Oncology Group

      2012 - Present

      Selected Presentations & Talks

      Local Presentations

      1. 2020. New Treatments for Sickle Cell Disease. Conference. UT Health. McGovern Medical School. Houston, TX, US.

      Regional Presentations

      1. 2025. Cell and Gene Therapy for Hemoglobinopathies. Time to Stop the Pain, Transfusions, and Iron Overload. Conference. Grand Rounds.
      2. 2021. Hematopoietic Stem Cell Transplantation for Acute Lymphoblastic Leukemia. Update on Indications and Outcomes. Conference. Pediatric Grand Rounds. Duarte, CA.
      3. 2016. Hematopoietic Stem Cell Transplantation: Cure for Sickle Cell Disease. Conference. Grand Rounds. Brooklyn, New York, US.

      International Presentations

      1. 2022. T Replete vs T Deplete Haploidentical BMT. Pros & Cons. Invited. 2022 Egyptian Pediatric Hematology Oncology Society Annual International Conference (CCHE; 57357). Cairo, EC.
      2. 2022. Transplant Associated Thrombotic Microangiopathy Risk Stratification. Invited. 2022 Egyptian Pediatric Hematology Oncology Society Annual International Conference (CCHE; 57357). Cairo, EG.
      3. 2022. Role of Hematopoietic Stem Cell Transplantation and Immunotherapy in Ewing Sarcoma. Invited. National Cancer Institute, Cairo University & Children's Cancer Hospital Egypt (CCHE; 57357). Alexandria, EG.

      Formal Peers

      1. 2021. Pediatric Grand Rounds “Hematopoietic Stem Cell Transplantation for Acute Lymphoblastic Leukemia. Update on Indications and Outcomes". Invited. Duarte, CA, US.
      2. 2016. Grand Rounds. Hematopoietic Stem Cell Transplantation: Cure for Sickle Cell Disease. Invited. Brooklyn, NY, US.
      Read More
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      Grant & Contract Support

      Date: 2013 - 2015
      Title:Ruth L. Kirschstein National Research Service Award
      Funding Source:American Institute for Cancer Research (AICR)
      Role:Trainee
      ID:5T32CA009659-19

      Selected Publications

      Peer-Reviewed Articles

      1. Hudda, Z, Webster, A, Anderson, E, Badia, P, Bagatell, R, Bhar, S, Bidgoli, A, Boyd, K, Chaudhury, S, Cisneros, GS, Craddock, J, Davies, SM, Desai, AV, Drobatz, L, Dvorak, CC, Elkus, H, Fabrizio, VA, Foster, J, Fraint, E, Freedman, JL, Galvez, J, Garcia, M, Haight, AE, Higham, CS, Jodele, S, Kamat, A, Kaviany, S, Lehmann, L, Leung, KS, Lind, KT, Llaurador, G, Kapadia, M, Khazal, SJ, Massi, K, Mormann, M, Pater, L, Rangarajan, HG, Rotz, S, Sabulski, A, Sartain, SE, Schoettler, M, Sokol, E, Streby, KA, Stein, M, Verneris, M, Weiss, BD, Yazdani, S, Zheng, DJ, Dandoy, C. Acute Toxicities and Early Outcomes of Tandem Autologous Stem Cell Transplantation in Pediatric High-Risk Neuroblastoma. Transplantation and Cellular Therapy 32(2):199.e1-199.e12, 2026. e-Pub 2026. PMID: 41238193.
      2. Fan, AE, Alqahtani, S, Garnes, ND, Tewari, P, Petropoulos, D, Khazal, SJ, Mahadeo, KM, DePriest, P, Sheikh, IN. Bezlotoxumab as Treatment for Recurrent/Chronic Clostridioides difficile Infection in Pediatric Stem Cell Transplant Recipients. Pediatric Blood and Cancer 72(10), 2025. e-Pub 2025. PMID: 40879561.
      3. Ragoonanan, D, Abdel-Azim, H, Sharma, A, Bhar, S, McArthur, J, Madden, R, Rahrig, A, Bajwa, R, Wang, J, Sun, V, Wright, M, Lassiter, R, Shoberu, B, Kawedia, J, Khazal, SJ, Mahadeo, KM. Retrospective analysis of veno-occlusive disease/sinusoidal obstruction syndrome in paediatric patients undergoing hematopoietic cell transplantation -a multicentre study. The Lancet Regional Health - Americas 33, 2024. e-Pub 2024. PMID: 38616918.
      4. Marcoux, C, Saliba, RM, Wallis, W, Khazal, SJ, Ragoonanan, D, Rondon, G, Tewari, P, Popat, UR, Oran, B, Olson, AL, Bashir, Q, Qazilbash, MH, Alousi, AM, Hosing, C, Nieto, Y, Al-Atrash, G, Marin, D, Rezvani, K, Khouri, IF, Srour, S, Champlin, RE, Shpall, E, Kebriaei, P. Incidence and risk factors of early onset VOD/SOS differ in younger vs older adults after stem cell transplantation. Blood Advances 8(5):1128-1136, 2024. e-Pub 2024. PMID: 38266155.
      5. Pasvolsky, O, Bassett Jr, R, Ghanem, S, Cuglievan, B, Tewari, P, Hosing, C, Srour, S, Ramdial, JL, Mahadeo, KM, Khazal, SJ, Petropoulos, D, Popat, UR, Qazilbash, MH, Kebriaei, P, Champlin, RE, Shpall, E, Nieto, Y. Characteristics and outcomes of children, adolescents and young adults with relapsed/refractory non-hodgkin lymphoma undergoing autologous stem cell transplant. BMC cancer 23(1), 2023. e-Pub 2023. PMID: 38124057.
      6. Sarkar S, Connors JS, Sheikh I, Rav E, Wang Z, Bassett RL, Straubel M, Mahadeo KM, Tewari P, Petropoulos D, Hosing C, Ragoonanan D, Khazal S, Fucanan A, Bibal C. The Impact of Leukapheresis Collection on Patients Undergoing Chimeric Antigen T-Cell Receptor Therapy with Tisagenlecleucel. Blood 142(1):6944, 2023. e-Pub 2023.
      7. Nieto Y, Pasvolsky O, Bassett R, Ghanem S, Cuglievan B, Tewari P, Hosing C, Sr S, Ramdial J, Mahadeo K, Khazal S, Petropoulos D, Popat U, Qazilbash M, Kebriaei P, Champlin R, Shpall E. Characteristics and outcomes of children, adolescents and young adults with relapsed/refractory non-Hodgkin lymphoma undergoing autologous stem cell transplant. Res Sq, 2023. e-Pub 2023. PMID: 36798261.
      8. Sheikh IN, Alqahtani S, Ragoonanan D, Tewari P, Petropoulos D, Mahadeo KM, Popat U, Shpall EJ, Khazal S. Post-transplant cyclophosphamide after matched sibling and unrelated donor hematopoietic stem cell transplantation in pediatric patients with acute myeloid leukemia. Int J Mol Sci 23(15), 2022. e-Pub 2022. PMID: 35955881.
      9. Nieto Y, Gruschkus S, Valdez BC, Jones RB, Anderlini P, Hosing C, Popat U, Qazilbash M, Kebriaei P, Alousi A, Saini N, Srour S, Rezvani K, Ramdial J, Barnett M, Gulbis A, Shigle TL, Ahmed S, Iyer S, Lee H, Nair R, Parmar S, Steiner R, Dabaja B, Pinnix C, Gunther J, Cuglievan B, Mahadeo K, Khazal S, Chuang H, Champlin R, Shpall EJ, Andersson BS. Improved outcomes of high-risk relapsed Hodgkin lymphoma patients after high-dose chemotherapy: a 15-year analysis. Haematologica, 2022. e-Pub 2021. PMID: 33951890.
      10. Gaballa MR, Banerjee PP, Milton DR, Jiang X, Ganesh C, Khazal S, Nandivada V, Islam S, Kaplan M, Daher M, Basar R, Alousi A, Mehta RS, Alatrash G, Khouri IF, Oran B, Marin D, Popat UR, Olson AL, Tewari P, Jain N, Jabbour EJ, Ravandi F, Kantarjian HM, Chen K, Champlin RE, Shpall EJ, Rezvani K, Kebriaei P. Blinatumomab maintenance after allogeneic hematopoietic cell transplantation for b-lineage acute lymphoblastic leukemia. Blood, 2022. e-Pub 2021. PMID: 34914826.
      11. Gibson A, Ragoonanan D, Tewari P, Petropoulos D, Rodriguez N, DiNardo C, Mahadeo KM, Khazal S. Non-myeloablative umbilical cord blood transplantation for atypical dyskeratosis congenita. Pediatr Transplant:e14157, 2022. e-Pub 2021. PMID: 34626046.
      12. Tambaro FP, Ragoonanan D, Tewari P, Petropoulos D, Aung FM, Mahadeo KM, Khazal S. The role of granulocyte transfusions in optimizing candidacy for chimeric antigen receptor T-cell therapy in patients with treatment-refractory infections. J Pediatr Hematol Oncol, 2022. e-Pub 2021. PMID: 33625094.
      13. Ariagno S, Ragoonanan D, Khazal S, Mahadeo KM, Cisneros GS, Zinter MS, Blacken RA, Mohan G, Lehmann LE, Ferdjallah A, Mara KC, Kohorst MA. Prior COVID-19 infection may increase risk for developing endothelial dysfunction following hematopoietic cell transplantation. Front Oncol 12:1000215, 2022. e-Pub 2022. PMID: 36733348.
      14. Ragoonanan D, Bhar S, Mohan G, Beltramo F, Khazal S, Hurley C, Andersen C, Margossian S, Neelapu SS, Shpall E, Gutierrez C, Tewari P, Shoberu B, Talleur A, McCall D, Nunez C, Cuglievan B, Tambaro FP, Petropoulos D, Abdel-Azim H, Mahadeo KM. A multicenter study of ICU resource utilization in pediatric, adolescent and young adult patients post CAR-T therapy. Front Oncol 12:1022901, 2022. e-Pub 2022. PMID: 36353531.
      15. Gibson A, Trabal A, McCall D, Khazal S, Toepfer L, Bell DH, Roth M, Mahadeo KM, Nunez C, Short NJ, DiNardo C, Konopleva M, Issa GC, Ravandi F, Jain N, Borthakur G, Kantarjian HM, Jabbour E, Cuglievan B. Venetoclax for children and adolescents with acute lymphoblastic leukemia and lymphoblastic lymphoma. Cancers (Basel) 14(1), 2021. e-Pub 2021. PMID: 35008312.
      16. Khazal S, Kebriaei P. Hematopoietic cell transplantation for acute lymphoblastic leukemia: review of current indications and outcomes. Leuk Lymphoma:1-14, 2021. e-Pub 2021. PMID: 34080951.
      17. Ragoonanan D, Khazal S, Abdel-Azim H, McCall D, Cuglievan B, Tambaro FP, Ahmad AH, Rowan CM, Gutierrez C, Schadler K, Li S, Di Nardo M, Chi L, Gulbis AM, Shoberu B, Mireles ME, McArthur J, Kapoor N, Miller J, Fitzgerald JC, Tewari P, Petropoulos D, Gill JB, Duncan CN, Lehmann LE, Hingorani S, Angelo JR, Swinford RD, Steiner ME, Tejada FNH, Martin PL, Auletta J, Choi SW, Bajwa R, Garnes ND, Kebriaei P, Rezvani K, Wierda WG, Neelapu SS, Shpall EJ, Corbacioglu S, Mahadeo KM. Author correction: diagnosis, grading and management of toxicities from immunotherapies in children, adolescents and young adults with cancer. Nat Rev Clin Oncol 18(7):468, 2021. e-Pub 2021. PMID: 33731864.
      18. Dandoy CE, Rotz S, Alonso PB, Klunk A, Desmond C, Huber J, Ingraham H, Higham C, Dvorak CC, Duncan C, Schoettler M, Lehmann L, Cancio M, Killinger J, Davila B, Phelan R, Mahadeo KM, Khazal S, Lalefar N, Vissa M, Myers K, Wallace G, Nelson A, Khandelwal P, Bhatla D, Gloude N, Anderson E, Huo J, Roehrs P, Auletta JJ, Chima R, Lane A, Davies SM, Jodele S. A pragmatic multi-institutional approach to understanding transplant-associated thrombotic microangiopathy after stem cell transplant. Blood Adv 5(1):1-11, 2021. e-Pub 2021. PMID: 33570619.
      19. Brown BD, Tambaro FP, Kohorst M, Chi L, Mahadeo KM, Tewari P, Petropoulos D, Slopis JM, Sadighi Z, Khazal S. Immune effector cell associated neurotoxicity (ICANS) in pediatric and young adult patients following chimeric antigen receptor (CAR) T-cell therapy: Can we optimize early diagnosis?. Front Oncol 11:634445, 2021. e-Pub 2021. PMID: 33763368.
      20. Kohorst MA, Khazal S, Tewari P, Petropoulos D, Mescher B, Wang J, Mahadeo KM, Kelley JM. Transfusion reactions in pediatric and adolescent young adult haematology oncology and immune effector cell patients. EClinicalMedicine 26:100514, 2020. e-Pub 2020. PMID: 32964199.
      21. Tambaro FP, Khazal S, Nunez C, Ragoonanan D, Tewari P, Petropoulos D, Kebriaei P, Wierda WG, Mahadeo KM. Complete remission in refractory acute lymphoblastic leukemia using blinatumomab after failure of response to CD-19 chimeric antigen receptor T-cell therapy. Clin Case Rep 8(9):1678-1681, 2020. e-Pub 2020. PMID: 32983475.
      22. Harden A, Ragoonanan D, Anildes-Gubman D, McCall D, Faltus K, Featherston S, Shoberu B, Moffet JR, Petropoulos D, Khazal S, Razvi S, Mahadeo KM, Tewari P. Chimeric antigen receptor, teamwork, education, assessment, and management (CAR-TEAM): a simulation-based inter-professional education (IPE) intervention for management of car toxicities. Front Oncol 10:1227, 2020. e-Pub 2020. PMID: 32850365.
      23. Ragoonanan D, Khazal S, Wang J, Payne A, Kohorst M, Harden A, Tewari P, Petropoulos D, Shoberu B, Kebriaei P, Mahadeo KM, Tambaro FP. Improved detection of sinusoidal obstructive syndrome using pediatric-AYA diagnostic criteria and severity grading. Bone Marrow Transplant 56(1):175-184, 2020. e-Pub 2020. PMID: 32665674.
      24. Khazal S, Polishchuk V, Soffer G, Prinzing S, Gill J, Mahadeo KM. Allogeneic hematopoietic stem cell transplantation is associated with cure and durable remission of late-onset primary isolated central nervous system hemophagocytic lymphohistiocytosis. Pediatr Transplant 22(1), 2018. e-Pub 2018. PMID: 29239076.
      25. Adam E, Kim HN, Gang EJ, Schnair C, Lee S, Lee S, Khazal S, Kosoyan O, Konopleva M, Parekh C, Bhojwani D, Wayne AS, Abdel-Azim H, Heisterkamp N, Kim YM. The PI3Kδ inhibitor idelalisib inhibits homing in an in vitro and in vivo model of B ALL. Cancers (Basel) 9(9), 2017. e-Pub 2017. PMID: 28891959.
      26. Li L, Qi X, Sun W, Abdel-Azim H, Lou S, Zhu H, Prasadarao NV, Zhou A, Shimada H, Shudo K, Kim YM, Khazal S, He Q, Warburton D, Wu L. Am80-GCSF synergizes myeloid expansion and differentiation to generate functional neutrophils that reduce neutropenia-associated infection and mortality. EMBO Mol Med 8(11):1340-1359, 2016. e-Pub 2016. PMID: 27737899.
      27. Polishchuk V, Khazal S, Berulava G, Roth M, Mahadeo KM. 5-azacitidine monotherapy followed by related haploidentical hematopoietic stem cell transplantation achieves durable remission in a pediatric patient with acute undifferentiated leukemia refractory to high-dose chemotherapy. Pediatr Blood Cancer 63(6):1111-2, 2016. e-Pub 2016. PMID: 26914221.
      28. Abdel-Azim H, Mahadeo KM, Zhao Q, Khazal S, Kohn DB, Crooks GM, Shah AJ, Kapoor N. Unrelated donor hematopoietic stem cell transplantation for the treatment of non-malignant genetic diseases: An alemtuzumab based regimen is associated with cure of clinical disease; earlier clearance of alemtuzumab may be associated with graft rejection. Am J Hematol 90(11):1021-6, 2015. e-Pub 2015. PMID: 26242764.

      Review Articles

      1. Cevering CK, Abdel-Azim H, Khazal SJ, Casassa C. Immune Effector Cell-Associated Neurotoxicity Syndrome: A Practical Overview for the General Neurologist. Neurol Clin Pract 16(1):e200575, 2026. e-Pub 2026. PMID: 41445934.
      2. Cuglievan, B, Kantarjian, HM, Rubnitz, JE, Cooper, T, Zwaan, CM, Pollard, J, DiNardo, C, Kadia, TM, Guest, E, Short, NJ, McCall, DC, Daver, N, Nunez, CA, Haddad, FG, Garcia, MB, Bhalla, K, Maiti, A, Catueno, S, Fiskus, WC, Carter, BZ, Gibson, A, Roth, M, Khazal, SJ, Tewari, P, Abbas, HA, Bourgeois, W, Andreeff, M, Shukla, N, Truong, D, Connors, JS, Ludwig, JA, Stutterheim, J, Salzer, E, Juul-Dam, KL, Sasaki, K, Mahadeo, KM, Tasian, SK, Borthakur, G, Dickson, S, Jain, N, Jabbour, EJ, Meshinchi, S, Garcia-Manero, G, Ravandi, F, Stein, EM, Kolb, EA, Issa, GC. Menin inhibitors in pediatric acute leukemia. Leukemia 38(10):2073-2084, 2024. e-Pub 2024. PMID: 39179671.
      3. Cuglievan, B, Connors, JS, He, J, Khazal, SJ, Yedururi, S, Dai, J, Garces, S, Quesada, AE, Roth, M, Garcia, M, McCall, DC, Gibson, A, Ragoonanan, D, Petropoulos, D, Tewari, P, Nunez, CA, Mahadeo, KM, Tasian, SK, Lamble, AJ, Pawlowska, A, Hammond, DE, Maiti, A, Haddad, FG, Senapati, J, Daver, N, Gangat, N, Konopleva, M, Meshinchi, S, Pemmaraju, N. Blastic plasmacytoid dendritic cell neoplasm. Leukemia 37(9):1767-1778, 2023. e-Pub 2023. PMID: 37452102.
      4. Munir, F, Hardit, V, Sheikh, IN, Alqahtani, S, He, J, Cuglievan, B, Hosing, C, Tewari, P, Khazal, SJ. Classical Hodgkin Lymphoma. International journal of molecular sciences 24(12), 2023. e-Pub 2023. PMID: 37373245.
      5. He, J, Munir, F, Ragoonanan, D, Zaky, W, Khazal, SJ, Tewari, P, Fueyo-Margareto, J, Gomez-Manzano, C, Jiang, H. Combining CAR T Cell Therapy and Oncolytic Virotherapy for Pediatric Solid Tumors. Immuno 3(1):37-56, 2023. e-Pub 2023.
      6. Munir F, He J, Connors J, Garcia M, Gibson A, McCall D, Nunez C, Dinh CN, Robusto L, Roth M, Khazal S, Tewari P, Cuglievan B. Translational advances in the treatment of childhood acute lymphoblastic leukemia: narrative review of current and emerging molecular and immunotherapies. Transl Pediatr 12(3):487-502, 2023. e-Pub 2023. PMID: 37035397.
      7. Ragoonanan D, Sheikh IN, Gupta S, Khazal S, Tewari P, Petropoulos D, Li S, Mahadeo KM. The evolution of chimeric antigen receptor t-cell therapy in children, adolescents and young adults with acute lymphoblastic leukemia. Biomedicines 10(9), 2022. e-Pub 2022. PMID: 36140387.
      8. Sheikh IN, Elgehiny A, Ragoonanan D, Mahadeo KM, Nieto Y, Khazal S. Management of aggressive non-hodgkin lymphomas in the pediatric, adolescent, and young adult population: an adult vs. pediatric perspective. Cancers (Basel) 14(12), 2022. e-Pub 2022. PMID: 35740580.
      9. Di Nardo M, Ahmad AH, Merli P, Zinter MS, Lehman LE, Rowan CM, Steiner ME, Hingorani S, Angelo JR, Abdel-Azim H, Khazal S, Shoberu B, McArthur J, Bajwa R, Ghafoor S, Shah SH, Sandhu H, Moody K, Brown BD, Mireles ME, Steppan D, Olson T, Raman L, Bridges B, Duncan CN, Choi SW, Swinford R, Paden M, Fortenberry JD, Peek G, Tissieres P, De Luca D, Locatelli F, Corbacioglu S, Kneyber M, Franceschini A, Nadel S, Kumpf M, Loreti A, Wösten-Van Asperen R, Gawronski O, Brierley J, MacLaren G, Mahadeo KM. Extracorporeal membrane oxygenation in children receiving haematopoietic cell transplantation and immune effector cell therapy: an international and multidisciplinary consensus statement. Lancet Child Adolesc Health 6(2):116-128, 2022. e-Pub 2022. PMID: 34895512.
      10. Sheikh IN, Ragoonanan D, Franklin A, Srinivasan C, Zhao B, Petropoulos D, Mahadeo KM, Tewari P, Khazal S. Cardiac relapse of acute lymphoblastic leukemia following hematopoietic stem cell transplantation: a case report and review of literature. Cancers (Basel) 13(22), 2021. e-Pub 2021. PMID: 34830969.
      11. Ragoonanan D, Khazal S, Abdel-Azim H, McCall D, Cuglievan B, Tambaro FP, Ahmad AH, Rowan CM, Gutierrez C, Schadler K, Li S, Di Nardo M, Chi L, Gulbis AM, Shoberu B, Mireles ME, McArthur J, Kapoor N, Miller J, Fitzgerald JC, Tewari P, Petropoulos D, Gill JB, Duncan CN, Lehmann LE, Hingorani S, Angelo JR, Swinford RD, Steiner ME, Hernandez Tejada FN, Martin PL, Auletta J, Choi SW, Bajwa R, Dailey Garnes N, Kebriaei P, Rezvani K, Wierda WG, Neelapu SS, Shpall EJ, Corbacioglu S, Mahadeo KM. Diagnosis, grading and management of toxicities from immunotherapies in children, adolescents and young adults with cancer. Nat Rev Clin Oncol 18(7):435-453, 2021. e-Pub 2021. PMID: 33608690.
      12. Ragoonanan D, Khazal S, Mejia R, Ewing L, Durand JB, Bashoura L, Tayar J, Dailey Garnes N, Petropoulos D, Tewari P, Bhatti M, Ahmad AH, Cortes J, Razvi S, McBeth K, Swinford R, Shoberu B, Waseemuddin W, Chi L, Gill JB, Zaky W, Daw N, Gutierrez C, Tereffe W, Kebriaei P, Rezvani K, Shpall EJ, Champlin RE, Mahadeo KM. Case discussion and literature review: cancer immunotherapy, severe immune-related adverse events, multi-inflammatory syndrome, and severe acute respiratory syndrome coronavirus 2. Front Oncol 11:625707-625707, 2021. e-Pub 2021. PMID: 33614514.
      13. Khazal S, Kebriaei P. Debate: Transplant is still necessary in the era of targeted cellular therapy for acute lymphoblastic leukemia. Clin Lymphoma Myeloma Leuk 20(11):713-719, 2020. e-Pub 2020. PMID: 32694050.
      14. Kruse A, Abdel-Azim N, Kim HN, Ruan Y, Phan V, Ogana H, Wang W, Lee R, Gang EJ, Khazal S, Kim YM. Minimal residual disease detection in acute lymphoblastic leukemia. Int J Mol Sci 21(3), 2020. e-Pub 2020. PMID: 32033444.
      15. Mahadeo KM, Bajwa R, Abdel-Azim H, Lehmann LE, Duncan C, Zantek N, Vittorio J, Angelo J, McArthur J, Schadler K, Chan S, Tewari P, Khazal S, Auletta JJ, Choi SW, Shoberu B, Kalwak K, Harden A, Kebriaei P, Abe JI, Li S, Moffet JR, Abraham S, Tambaro FP, Kleinschmidt K, Richardson PG, Corbacioglu S, Lung Injury PA, Network SI, for Blood TPDWPOTES, Transplantation M. Diagnosis, grading, and treatment recommendations for children, adolescents, and young adults with sinusoidal obstructive syndrome: an international expert position statement. Lancet Haematol 7(1):e61-e72, 2020. e-Pub 2020. PMID: 31818728.
      16. Mahadeo KM, Khazal S, Abdel-Azim H, Fitzgerald JC, Taraseviciute A, Bollard CM, Tewari P, Duncan C, Traube C, McCall D, Steiner ME, Cheifetz IM, Lehmann LE, Mejia R, Slopis JM, Bajwa R, Kebriaei P, Martin PL, Moffet J, McArthur J, Petropoulos D, O'Hanlon Curry J, Featherston S, Foglesong J, Shoberu B, Gulbis A, Mireles ME, Hafemeister L, Nguyen C, Kapoor N, Rezvani K, Neelapu SS, Shpall EJ, Lung Injury PA, Network SI. Management guidelines for paediatric patients receiving chimeric antigen receptor T cell therapy. Nat Rev Clin Oncol 16(1):45-63, 2019. e-Pub 2019. PMID: 30082906.

      Abstracts

      1. Zucenka A, Issa GC, Arellano M, Khazal S, Khera N, Stock W, Cuglievan B, Gu Y, Nguyen HV, Smith AR, Stein EM. Revumenib Maintenance Therapy Following Revumenib-Induced Remission and Transplant. Blood 142(1):4950, 2023. e-Pub 2023.
      2. Khazal S, Gill JB, Foglesong J, Yedururi S, Morani A, Sui D, Bassett RL, Gettys S, Tewari P, Mahadeo K, Gorlick RG, Shpall EJ, Rezvani K, C Daw AN. A phase 1 dose escalation trial of ex-vivo expanded allogeneic cord blood–derived natural killer cell immunotherapy for pediatric solid tumor malignancies. ASCO Annual Meeting 41(16):2546, 2023. e-Pub 2023.
      3. Ragoonanan D, Harden A, Elgehiny A, Nunez C, Roth ME, McCall D, Cuglievan B, Tewari P, Petropoulos D, Mahadeo KM, Khazal SJ. DNMT3A Mutations Should be Considered in the Risk Stratification for Pediatric and Adolescent and Young Adult Patients with Acute Myeloid Leukemia. Blood 138(1):1308, 2021. e-Pub 2021.
      4. Trabal A, Gibson A, McCall D, Mahadeo KM, Toepfer L, Roth ME, Buzbee M, Kadia TM, Garces S, Konopleva M, DiNardo CD, Daver N, Short NJ, Issa GC, Ravandi F, Nunez C, Khazal SJ, Paek H, Brackett J, Garcia-Manero G, Kantarjian H, Marcogliese AN, Dreyer Z, Redell MS, Yi JS, Stevens AM, Cuglievan B. Venetoclax for Acute Myeloid Leukemia in Pediatric Patients: A Texas Medical Center Collaboration. Blood 138(1):1247, 2021. e-Pub 2021.
      5. Kohorst MA, Mahadeo KM, Khazal SJ, Tewari P, Petropoulos D, Mescher B, Kelley JM. Transfusion Reactions in Pediatric and Young Adult Hematopoietic Stem Cell Transplant and Oncology Patients. Transplantation and Cellular Therapy 26(3):S149, 2020. e-Pub 2020.
      6. Nieto Y, Gruschkus SK, Jones RB, Valdez BC, Timmons M, Hosing C, Anderlini P, Kebriaei P, Popat UR, Qazilbash MH, Alousi AM, Srour SA, Saini N, Ramdial J, Im JS, Shpall EJ, Rezvani K, Gulbis A, Shigle TL, Mahadeo KM, Khazal S, Khouri IF, Dabaja BS, Pinnix CC, Gunther JR, Lee H, Ahmed S, Steiner RE, Iyer SP, Nair R, Parmar S, Cuglievan B, Maadani F, Rondon G, Champlin RE, Andersson BS. Factors Associated with the Improvement of Outcomes of High-Risk Relapsed Hodgkin Lymphoma (HL) Patients Receiving High-Dose Chemotherapy (HDC) and Autologous Stem-Cell Transplantation (ASCT): The MD Anderson Cancer Center Experience. Blood 136(Supplement_1):17-18, 2020. e-Pub 2020.
      7. Brown B, Mahadeo K, Khazal S, Petropoulos D, Tewari P, Slopis J, Tambaro P, Sadighi AZ. IMMUNE EFFECTOR CELL ASSOCIATED NEUROTOXICITY (ICANS) AMONG PEDIATRIC AND AYA PATIENTS: MD ANDERSON CANCER CENTER EXPERIENCE. Neuro-Oncology 22(Supplement_2):ii116, 2020. e-Pub 2020.
      8. Tambaro P, Mahadeo KM, Khazal SJ, Tewari P, Petropoulos D, Slopis JM, Brown BD, Sadighi Z. Immune Effector Cell Associated Neurotoxicity (ICANS) Among Pediatric and AYA Patients: MD Anderson Cancer Center Experience. Transplantation and Cellular Therapy 26(3):S316, 2020. e-Pub 2020.
      9. Dandoy CE, Rotz S, Alonso PB, Higham C, Dvorak CC, Duncan C, Schoettler M, Lehmann L, Cancio M, Killinger J, Davila B, Kasprzyk ZA, Phelan R, Mahadeo K, Khazal S, Steiner M, Smith A, Lalefar N, Vissa M, Bhatla D, Gloude N, Anderson E, Huo J, Roehrs P, Auletta J, Davies S, Chima R, Jodele S. Transplant associated thrombotic microangiopathy after transplant: A PBMTC/PALISI multi center collaborative. Pediatric Blood & Cancer 66(S2):e27713, 2019. e-Pub 2019.
      10. Harden A, Anildes-Gumba D, Ragoonanan D, McCall D, Khazal S, Featherston S, Faltus K, Shoberu B, Mahadeo KM, Razvi S, Tewari P. SIMULATION BASED EDUCATION FOR THE EVIDENCE BASED MANAGEMENT OF CHIMERIC ANTIGEN RECEPTOR -T CELL RELATED ENCEPHALOPATHY SYNDROME AND CYTOKINE RELEASE SYNDROME. Pediatric Blood & Cancer 66(S2):e27713, 2019. e-Pub 2019.
      11. Batth IS, Zaky W, Khatua S, Daw NC, Mahadeo KM, Khazal S, Albert A, Huang W, Chen D, Gill JB, Kleinerman E, Gorlick R, Li S. Automated capture and analysis of circulating tumor cells across different types of tumors in pediatric cancer patients. Cancer Research 79(13 Supplement):1345, 2019. e-Pub 2019.
      12. Tambaro F, Ragoonanan D, Khazal S, Petropoulos D, Tewari P, Kebriaei P, Wierda W, Kohorst M, Mahadeo K. Sinusoidal Obstructive Syndrome Among Pediatric and Adolescent and Young Adult Patients: Analysis of Pediatric EBMT Diagnostic and Severity Criteria at MD Anderson. Blood 134(Supplement 1):4495-4495, 2019. e-Pub 2019.
      13. McCall D, Featherston S, Curry JO, Khazal S, Mahadeo KM. Immune Effector Cell Transition to Standard of Care: The Children’s Cancer Hospital at MD Anderson Cancer Center Experience. Pediatric Blood & Cancer 65(S1):e27057, 2018. e-Pub 2018.
      14. Khazal S, Gill J, Gorlick R, Fernandez P, Benard E, Mahadeo KM. High Dose Chemotherapy Followed By Autologous Stem Cell Rescue for High Risk Soft Tissue Sarcoma: Retrospective Review. Transplantation and Cellular Therapy 24(3):S138, 2018. e-Pub 2018.
      15. Khazal S, Fernandez P, Benard E, Shoberu B, Manwani D, and Mahadeo KM. Allogeneic Blood and Marrow Transplantation for Pediatric Patients with Sickle Cell Anemia: An Institutional Experience. Blood 130(Supplement 1):4581-4581, 2017. e-Pub 2017.
      16. Khazal S, Manwani D, Mahadeo KM. Stable Mixed Donor Chimerism after Allogeneic Stem Cell Transplantation Using a Reduced Intensity Conditioning Regimen in a 4 Year Old Boy with Congenital Non Spherocytic Hemolytic Anemia Secondary to Hexokinase Deficiency. Transplantation and Cellular Therapy 22(3):S331, 2016. e-Pub 2016.
      17. Polishchuk V, Khazal S, Soffer G, Prinzing S, Gill J, Mahadeo KM. Reduced Intensity Conditioning Followed By Allogeneic Hematopoietic Stem Cell Transplantation Resulted in Cure of a 15 Year Old Male with Primary Isolated CNS Late Onset Familial Hemophagocytic Lymphohistiocytosis. Transplantation and Cellular Therapy 22(3):S347 - S348, 2016. e-Pub 2016.

      Book Chapters

      1. Khazal, SJ, Kebriaei, P. Allogeneic Hematopoietic Cell Transplantation for Patients With Acute Lymphoblastic Leukemia, 217-232, 2023.
      2. Khazal S, Ragoonanan D, Mahadeo AK. Care of the Critically Ill Pediatric Hematopoietic Cell Transplant Patient. In: Pediatric Critical Care Study Guide 2nd edition. 2nd. Springer International Publishing, 2021.
      3. Khazal, S, Mahadeo, K. Chimeric Antigen Receptor (CAR) T cell therapy. In: Pediatric Oncologic Critical Care. Springer, Cham, pp 2035-2047, 2018.
      4. Khazal S, Galvez Silva JR, Thakar M, Margolis D. Bone Marrow Failure. In: Bone Marrow Failure. In: Critical Care of The Pediatric Immunocompromised Hematology/Oncology Patient: An Evidence-Based Guide. Springer International Publishing AG, Cham, 2018.
      5. Gang E, Hinh C, Khazal S, Kim Y. Molecular Pathogenesis of ALL. In: Contemporary Management of Acute Lymphoblastic Leukemia. Jp Medical Ltd, 2014.

      Letters to the Editor

      1. Sheikh, IN, Alqahtani, S, Okeleji, O, Brown, BD, Ragoonanan, D, Waseemuddin, M, Shoberu, B, Kawedia, J, Khazal, SJ, Connors, JS, Petropoulos, D, Tewari, P, Bonfim, C, Driscoll, TA, DePriest, BP, Mahadeo, KM. Pre-transplant immunosuppression in pediatric patients undergoing haploidentical stem cell transplant for sickle cell disease is associated with positive outcomes. Bone marrow transplantation 61: 241-244, 2026.
      2. Okeleji, O, Khazal, SJ, Mahadeo, KM, Ragoonanan, D, Rodriguez, NI, DiNardo, C, Connors, JS, Petropoulos, D, Tewari, P, Sheikh, IN. Allogeneic Hematopoietic Stem Cell Transplant for an Unknown Inherited Bone Marrow Failure Syndrome With a Novel Compound Heterozygous Mutation. Pediatric Blood and Cancer 72, 2025.
      3. Sheikh, IN, Uwaezuoke, D, Okeleji, O, Quesada, AE, Herzog, CE, Ragoonanan, D, Tewari, P, Petropoulos, D, McCall, DC, Nunez, CA, Roth, M, Cuglievan, B, Khazal, SJ. Treatment of a Pediatric Patient with Core Binding Factor Acute Myeloid Leukemia Post-Cytotoxic Therapy With Cytarabine, Daunorubicin, and Gemtuzumab Followed by Stem Cell Transplantation. Pediatric Blood and Cancer 72, 2025.
      4. Ragoonanan D, Tambaro FP, Khazal SJ, Tewari P, Petropoulos D, Champlin R, Mahadeo KM. Cytokine release syndrome and complete remission of extra medullary acute lymphoblastic leukemia of the breast with CAR-T and radiation therapy. Pediatr Blood Cancer 68: e28839, 2021.
      5. Kohorst MA, Nunez CA, Tewari P, Petropoulos D, Mahadeo KM, Neelapu SS, Shpall EJ, Khazal S. Primary mediastinal large B-cell lymphoma in paediatric and adolescent patients: emerging questions in the era of immunotherapy. Br J Haematol 190: e114-e117, 2020.
      6. Khazal S, Ragoonanan D, Hosing C, Williams L, Medeiros LJ, Mahadeo KM, Thompson PA. Epstein - Barr virus specific cytotoxic T lymphocytes for the treatment of severe epstein-barr virus mucocutaneous ulcer. Br J Haematol 189: e33-e36, 2020.
      7. Khazal S, Polishchuk V, Manwani D, Gallagher PG, Prinzing S, Mahadeo KM. Allogeneic bone marrow transplantation for treatment of severe hemolytic anemia attributable to hexokinase deficiency. Blood 128: 735-7, 2016.
      8. Khazal S, Abdel-Azim H, Kapoor N, Mahadeo KM. Overcoming psychosocial and developmental barriers to blood and marrow transplantation (BMT) in an adolescent/young adult (AYA) transgender patient with chronic myelogenous leukemia. Pediatric Hematology and Oncology 31: 765-767, 2014.
      9. Hsieh YT, Gang EJ, Shishido SN, Kim HN, Pham J, Khazal S, Osborne A, Esguerra ZA, Kwok E, Jang J, Bonig H, Biediger RJ, Vanderslice P, Kim YM. Effects of the small-molecule inhibitor of integrin α4, TBC3486, on pre-B-ALL cells. Leukemia 28: 2101-2104, 2014.
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