Sam Lo, MD
Department of Musculoskeletal Imaging, Division of Diagnostic Imaging
About Dr. Sam Lo
Present Title & Affiliation
Primary Appointment
Assistant Professor, Musculoskeletal Imaging, The University of Texas MD Anderson Cancer Center, Houston, Texas
Dual/Joint/Adjunct Appointment
Assistant Professor, Musculoskeletal Imaging, The University of Texas MD Anderson Cancer Center, Houston, Texas
Education & Training
Degree-Granting Education
| 2002 | Albert Einstein College of Medicine, New York, New York, US, Doctor of Medicine |
| 1998 | The Ohio State University, US, Bachelor of Science |
Postgraduate Training
| 2007-2008 | Clinical Fellowship, Musculoskeletal Radiology, Albert Einstein College of Medicine, New York, New York |
| 2003-2007 | Clinical Residency, Diagnostic Radiology, Main Line Health Systems (Bryn Mawr Hospital, Paoli Hospital, Lankenau Medical Center), Bryn Mawr, Pennsylvania |
| 2002-2003 | Clinical Residency, Orthopedic Surgery, Albert Einstein College of Medicine, New York, New York |
| 1996-1998 | Undergraduate Research Fellowship, American Society for Microbiology, Honors, Senior Thesis Funding, Ohio State University, Columbus, Ohio |
| 1996-1996 | Undergraduate Summer Research Fellowship, American Heart Association, Children's Hospital Medical Center, Cincinnati, Ohio |
| 1996-1996 | National Institutes of Health Student Research Fellowship, National Institutes of Health, National Cancer Institute, Bethesda, Maryland |
| 1994-1996 | Student Research Assistant, Pediatric Neurology, Ohio State University Hospitals; Children's Hospital Research Foundation, Columbus, Ohio |
Licenses & Certifications
| 2008 | Texas Medical Board |
| 2007 | American Board of Radiology |
Experience & Service
Administrative Appointments/Responsibilities
Deputy Chair, Musculoskeletal Imaging Dept, The University of Texas MD Anderson Cancer Center, Houston, Texas, 2025 - Present
Patient Experience Officer, Musculoskeletal Imaging Dept, The University of Texas MD Anderson Cancer Center, Houston, Texas, 2025 - Present
Diagnostic Imaging Site Director Bellaire, University of Texas MD Anderson Cancer Center, Houston, Texas, 2024 - Present
Patient Safety Quality Officer, Musculoskeletal Imaging Dept, The University of Texas MD Anderson Cancer Center, Houston, Texas, 2024 - Present
Other Professional Positions
Radiology Representative at the Sarcoma Surgical Oncology Conference, The University of Texas MD Anderson Cancer Center, Houston, Texas, 2024 - Present
Radiology Representative at the Spine Stereotactic Radiosurgery Conference, The University of Texas MD Anderson Cancer Center, Houston, Texas, 2024 - Present
Radiology Representative at the Plasma Cell Dyscrasia (aka myeloma) Conference, The University of Texas MD Anderson Cancer Center, Houston, Texas, 2024 - Present
Radiology Representative at the Orthopedics Morbidity and Mortality Conference, The University of Texas MD Anderson Cancer Center, Houston, Texas, 2023 - Present
Radiology Representative at the Sarcoma Multidisciplinary Conference, The University of Texas MD Anderson Cancer Center, Houston, Texas, 2023 - Present
Intramural Institutional Committee Activities
Member, Cancer Network Sarcoma Multidisciplinary Conference, The University of Texas MD Anderson Cancer Center, 2025 - Present
Member, Musculoskeletal Leadership Committee, The University of Texas MD Anderson Cancer Center, 2025 - Present
Member, DI-Safety, Quality & Value Functional Committee, The University of Texas MD Anderson Cancer Center, 2024 - Present
Representative, Musculoskeletal Imaging Quality Assurance, The University of Texas MD Anderson Cancer Center, 2024 - Present
Member, DI Clinical Functional Committee, The University of Texas MD Anderson Cancer Center, 2024 - Present
Member, Advanced Bone and Soft Tissue Imaging (ABASTI) Lab, The University of Texas MD Anderson Cancer Center, 2024 - Present
Member, Diagnostic Imaging Awards Committee, The University of Texas MD Anderson Cancer Center, 2024 - 2026
Honors & Awards
| 1998 | Award for Excellence in Scholarship, The Ohio State University College of Arts and Sciences |
| 1998 | Best Poster Award, The Ohio Branch American Society for Microbiology |
| 1998 | Tuition Assistance Scholarship, Albert Einstein College of Medicine Yeshiva University |
| 1997 | 1st Place Award, Richard J. and Martha D. Denman Undergraduate Research Forum |
| 1997 | Undergraduate Research Scholarship, Ohio State University College of Arts and Sciences |
| 1996 | Phi Beta Kappa |
| 1996 | The Honor Society of Phi Kappa Phi |
| 1993 | Excellence Scholarship, Ohio State University |
| 1993 | Freshman Foundation Scholarship, Ohio State University |
Selected Presentations & Talks
Local Presentations
- 2025. Diagnosis of Bone Lesions on Conventional Radiography. Invited. Musculoskeletal Pathology Conference. Houston, Texas, US.
- 2025. Interesting Cases. Invited. DI Education Conference Series. Houston, Texas, US.
- 2025. Pilot Study: Can a multiparametric-MRI (mp-MRI) model outperform RECIST for rhabdomyosarcoma (RMS) response assessment?. Invited. 2025 Advanced Bone and Soft Tissue Imaging Retreat. Houston, Texas, US.
- 2024. Diagnosis of Bone Lesions on Conventional Radiography. Invited. Musculoskeletal Pathology Conference. Houston, Texas, US.
International Presentations
- 2025. Pilot Study: Can a Multiparametric-MRI-derived Model Outperform RECIST Predicting Pathology Response in Rhabdomyosarcoma (RMS)?. Poster. 24th International Cancer Imaging Society Meeting. The Hague, NL.
- 2025. Multiparametric-MRI (mp-MRI) Baseline Signature Tumor Profile and Pre-surgical Predictive Treatment Response Model for Rhabdomyosarcoma (RMS). Poster. European Congress of Radiology. Vienna, AT.
Selected Publications
Peer-Reviewed Articles
- Valenzuela Perez RF, Duran-Sierra E, Hwang K-P, Ma J, Canjirathinkal M, Espinoza-Figueroa J, Askari A, Valenzuela P, Lo S, Madewell JE, Murphy Jr WA, Stafford J, Yadav N, Wu C, Amini B, Fung M, Costelloe CM. Beyond Radiologic Perception: A Pilot Quantitative and Radiomic Comparison between Zero-Echo-Time MRI and CT in Oncologic Metastatic Screening. J Radiol Oncol 10(1):009-015, 2026. e-Pub 2026.
- Shabat A, Siddappa VH, Lo SLH. Unexpected bony regrowth following partial hallux amputation in a diabetic neuropathic foot: A case report. Foot Ankle Surg (N Y) 5(4):100569, 2025. e-Pub 2025.
- Amini B, Valenzuela RF, Duran-Sierra E, Antony M, Costelloe CM, Nassif Haddad EF, Lo SLH, Valenzuela PV, Madewell JE, Espinoza JV, Murphy WA. Pilot study on leiomyosarcoma of the soft tissues: advanced imaging features predict response to neo-adjuvant therapy. J Radiol Oncol 9(3):075-084, 2025. e-Pub 2025.
- Valenzuela Perez RF, Duran-Sierra E, Antony M, Lo SLH, Amini B, Torres KE, Araujo D, Benjamin RS, Ma J, Hwang KP, Stafford RJ, Wu C, Madewell J, Espinoza JV, Murphy Jr WA, Cueto A, Valenzuela PV, Miranda-Zarate C, Costelloe C. Pilot Study Evaluating Multiparametric MRI (mp-MRI) Including Contrast-Enhanced Susceptibility Imaging (CE-SWI) in Predicting Pathology Treatment Response in Rhabdomyosarcoma. J Radiol Oncol 9(3):062-074, 2025. e-Pub 2025.
- Valenzuela RF, Duran-Sierra E, Antony M, Amini B, Lo S, Torres KE, Hwang KP, Ma J, Stafford RJ, Ratan R, Madewell JE, Araujo D, Murphy WA Jr, Costelloe CM. A follow-up study on the novel use of contrast-enhanced susceptibility-weighted imaging for extremity desmoid fibromatosis response assessment. Sci Rep 15(1):20515, 2025. e-Pub 2025. PMID: 40594237.
- Valenzuela RF, Duran-Sierra E, Antony M, Amini B, Lo S, Torres KE, Benjamin RS, Ma J, Hwang K, Stafford R, Araujo D, Bishop AJ, Ratan R, Wang W, Espinoza J, Valenzuela PV, Wu C, Madewell JE, Murphy Jr WA, Costelloe CM. Building a pre-surgical multiparametric-MRI-based morphologic, qualitative, semiquantitative, first and high-order radiomic predictive treatment response model for undifferentiated pleomorphic sarcoma to replace RECIST. Cancer Imaging 25(1):56, 2025. e-Pub 2025. PMID: 40281609.
- Valenzuela RF, Duran-Sierra E, Canjirathinkal M, Amini B, Torres KE, Benjamin RS, Ma J, Wang WL, Hwang KP, Stafford RJ, Wu C, Zarzour AM, Bishop AJ, Lo S, Madewell JE, Kumar R, Murphy WA Jr, Costelloe CM. Perfusion-weighted imaging with dynamic contrast enhancement (PWI/DCE) morphologic, qualitative, semiquantitative, and radiomics features predicting undifferentiated pleomorphic sarcoma (UPS) treatment response. Sci Rep 14(1):21681, 2024. e-Pub 2024. PMID: 39289469.
- Valenzuela RF, Duran-Sierra E, Canjirathinkal M, Amini B, Torres KE, Benjamin RS, Ma J, Wang WL, Hwang KP, Stafford RJ, Wu C, Zarzour AM, Bishop AJ, Lo S, Madewell JE, Kumar R, Murphy Jr WA, Costelloe CM. Radiomics by quantitative diffusion-weighted MRI for predicting response in patients with extremity soft-tissue undifferentiated pleomorphic sarcoma. J Radiol Oncol, 2024. e-Pub 2024.
- Lo SL, Elias I, Peterson JR, Chao W, Green J, Morrison WB. Stress fracture of the distal phalanx of the great toe in a professional ballet dancer: a case report. Am J Sports Med 35(9):1564-6, 2007. e-Pub 2007. PMID: 17337728.
- Burke SA, Lo SL, Krzycki JA. Clustered genes encoding the methyltransferases of methanogenesis from monomethylamine. J Bacteriol 180(13):3432-3440, 1998. e-Pub 1998. PMID: 9642198.
- Rutberg SE, Saez E, Lo S, Jang SI, Markova N, Spiegelman BM. Opposing activities of c-Fos and Fra-2 on AP-1 regulated transcriptional activity in mouse keratinocytes induced to differentiate by calcium and phorbol esters. Oncogene 15(11):1337-1346, 1997. e-Pub 1997. PMID: 9315102.
Review Articles
- Lo SL, Raskin K, Lester H. Carpal tunnel syndrome: a historical perspective. Hand Clin 18(2):211-7, 2002. e-Pub 2002. PMID: 12371024.
Abstracts
- Valenzuela RF, Duran-Sierra E, Antony M, Espinoza J, Madewell JE, Murphy W, Wells D, Amini B, Lo S. Pilot study on pathological response assessment in synovial sarcoma of the extremities based on multiparametric MRI. European Congress of Radiology, 2026. e-Pub 2026.
- Amin SE, Lo SLH, Lazar AJ, Wang W-L. Head and Neck Conventional and Dedifferentiated Chondrosarcomas: A Large Clinico-pathologic Study. 115th United States and Canadian Academy of Pathology (USCAP) Annual Meeting, 2026. e-Pub 2026.
- Valenzuela Perez RF, Duran-Sierra E, Antony M, Espinoza J, Costelloe CM, Madewell JE, Murphy W, Amini B, Lo S. Assessment of volumetric and modified choi MRI response in desmoid fibromatosis treatment with sorafenib versus nirogacestat. European Congress of Radiology, 2026. e-Pub 2026.
- Valenzuela RF, Duran-Sierra E, Antony M, Espinoza J, Costelloe CM, Murphy W, Wells D, Lo S. Opportunistic comparative analysis of quantitative radiomics between zero-echo-time MRI and CT on normal hip bone during oncologic metastatic screening. European Congress of Radiology, 2026. e-Pub 2026.
- Lo S, Valenzuela R, Amini B, Duran-Sierra E, Antony M, Murphy WA, Madewell JE, Costelloe CM. Pilot Study: Can a Multiparametric-MRI-derived Model Outperform RECIST Predicting Pathology Response in Rhabdomyosarcoma (RMS)?. 24th International Cancer Imaging Society Meeting and Annual Teaching Course 25(Suppl 1):5, 2025. e-Pub 2025.
- Duran Sierra E, Antony M, Valenzuela Perez RF, Amini B, Madewell JE, Costelloe CM, Lo S, Murphy WA. Multiparametric MRI Assessment of Neo-Adjuvant Therapy Response in Soft-Tissue Leiomyosarcoma. American Roentgen Ray Society Annual Meeting, 2025. e-Pub 2025.
- Valenzuela RF, Duran-Sierra E, Antony M, Murphy W, Madewell J, Costelloe CM, Lo S, Amini B, Espinoza J. Building a Predictive Multiparametric MRI Response Model for Undifferentiated Pleomorphic Sarcoma. American Roentgen Ray Society Annual Meeting, 2025. e-Pub 2025.
- Valenzuela Perez RF, Duran-Sierra E, Antony M, Murphy WA, Madewell JE, Costelloe CM, Lo S, Amini B, Espinoza J. Soft-Tissue Leiomyosarcoma: Building a Reliable Multiparametric MRI-Based Model for Neo-Adjuvant Therapy Response Assessment. 48th Society of Skeletal Radiology 2025 Annual Meeting, 2025. e-Pub 2025.
- Lo S, Valenzuela RF, Duran-Sierra E, Antony M, Amini B, Madewell JE, Murphy WA, Espinoza J, Costelloe CM. Multiparametric-MRI (mp-MRI) Baseline Signature Tumor Profile and Pre-surgical Predictive Treatment Response Model for Rhabdomyosarcoma (RMS). European Congress of Radiology, 2025. e-Pub 2025.
- Valenzuela RF, Duran-Sierra E, Antony M, Murphy W, Madewell J, Costelloe CM, Lo S, Amini B, Espinoza J. Soft-tissue leiomyosarcoma: Building a reliable multiparametric MRI-based model for neo-adjuvant therapy response assessment. European Congress of Radiology, 2025. e-Pub 2025.
- Lo SL, Zapadka M, Dravid V. Optimization of radiology resident education using PACS. 53rd Annual Meeting of The Association of University Radiologists Abstracts Book, 2005. e-Pub 2005.
- Lo SL, Tsai D, Dravid V. Pelvic congestion syndrome - clinical features, diagnosis and interventional management. 89th Annual Meeting of The Pennsylvania Radiological Society Official Program and Lankenau Institute for Medical Research Annual Colloquium Day Abstracts Book, 2004. e-Pub 2004.
- Weber RV, Wu J, Yu H, Weintraub J, Balog J, Lo SL, Strauch B. Pulsed magnetic energy (PME) applied to a transplanted rat tail arterial loop supports the rat groin cutaneous flap. American Society for Reconstructive Microsurgery General Meeting Abstracts Book, 2003. e-Pub 2003.
- Lo SL, Burke SA, Lee MP, Krzycki JA. Nearly identical copies of the monomethylamine methyltransferase genes exist in the genome of Methanosarcina barkeri MS. American Society for Microbiology 98th General Meeting Abstracts Book, 1998. e-Pub 1998.
Book Chapters
- Panush D, Lo S, Haygood TM. Principles of musculoskeletal imaging in cancer. Cancer rehabilitation: principles and practice. 3rd edition. In: Cancer Rehabilitation: Principles and Practice. 3rd Edition. Springer Publishing Company, 99-120.
Patient Reviews
CV information above last modified August 03, 2026