Senthil Damodaran, MD, PhD.
Department of Breast Medical Oncology, Division of Cancer Medicine
Present Title & Affiliation
Primary Appointment
Associate Professor (Joint appointment), Department of Investigational Cancer Therapeutics, Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX
ASCO ITE Task Force, American Society of Clinical Oncology, Alexandria, VA
Associate Professor (Joint appointment), Department of Translational Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX
Associate Professor, Department of Breast Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX
Dual/Joint/Adjunct Appointment
Associate Professor, Department of Investigational Cancer Therapeutics, The University of Texas MD Anderson Cancer Center, Houston, TX
Education & Training
Degree-Granting Education
2008 | University at Buffalo, Buffalo, New York, US, Biomedical Sciences, Pharmacology, Ph.D |
2001 | Madras Medical College, Chennai, IN, MD |
Postgraduate Training
2013-2015 | Fellowship, Breast Medical Oncology, The Ohio State University, Columbus, Ohio |
2012-2015 | Postdoctoral Fellow, (Mentor – Sameek Roychowdhury), The Ohio State University, Columbus, Ohio |
2011-2013 | Fellowship, Medical Oncology, The Ohio State University, Columbus, Ohio |
2008-2011 | Residency, Internal Medicine, University at Buffalo, Buffalo, New York |
Board Certifications
2014 | Medical Oncology, American Board of Internal Medicine |
2012 | Internal Medicine, American Board of Internal Medicine |
Experience & Service
Academic Appointments
Associate Professor, Department of Translational Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX, 2021 - 2023
Associate Professor, Department of Breast Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, 2016 - 2023
Clinical Instructor House Staff, The Ohio State University, Buffalo, NY, 2008 - 2011
Resident House Staff, University at Buffalo, Buffalo, NY, 2008 - 2011
Graduate Research Assistant, University at Buffalo, Buffalo, NY, 2002 - 2008
Other Appointments/Responsibilities
ASCO ITE Task Force, American Society of Clinical Oncology, Alexandria, VA, 2023 - Present
Guidelines Expert Panel, American Society of Clinical Oncology, Alexandria, VA, 2019 - 2019
Abemaciclib Project Team Member, National Cancer Institute-Cancer Therapy Evaluation Program, Bethesda, MD, 2019 - 2019
Breast Cancer Question Writing Member, American Board of Internal Medicine, Alexandria, 2018 - 2018
Rogaratinib Project Team Member, National Cancer Institute-Cancer Therapy Evaluation Program, Bethesda, MD, 2018 - 2018
ASCO Educational Book Expert Panel, American Society of Clinical Oncology, Chicago, 2017 - 2017
ASCO University Panel Member, American Society of Clinical Oncology, Alexandria, VA, 2017 - 2017
Institutional Committee Activities
Member, Faculty Senate, The University of Texas MD Anderson Cancer Center, 2021 - Present
Member, Scientific Review Committee (SRC2) MD Anderson Cancer Center, 2020 - 2021
Member, EMD Serono-MDACC Alliance Joint Steering Committee, 2019 - 2019
Member, Clinical Research Committee (CRC4), MD Anderson Cancer Center, 2017 - 2020
Member, Hematology and Oncology P and T Committee, The Ohio State University–James Cancer Center, 2013 - 2014
Vice Chair, University at Buffalo Residents Committee, 2010 - 2011
Elected Member, Residents Task Force, University at Buffalo, 2010 - 2011
Elected Member, Resident’s Advisory Committee, University at Buffalo, 2008 - 2010
Honors & Awards
Second place, “Renal Physiology Quiz”, Institute of Physiology and Experimental Medicine, Madras Medical College, India | |
Chief Minister’s Medical Scholarship | |
First place, “Cardiovascular Physiology Quiz”, Institute of Physiology and Experimental Medicine, Madras Medical College, India | |
Outstanding oral presentation, “Lymphomas”, Department of Surgery, Madras Medical College, India | |
Dean’s nomination, “Young Fellowship Award in Science”, Indian Institute of Sciences, India | |
SUNY GSEU Doctoral Award, University at Buffalo | |
GSA Scholarly Publication Award, University at Buffalo | |
Eastern Atlantic Student Research Forum, Travel Award, University of Miami | |
Second Place, Internal Medicine Quiz Competition, University at Buffalo | |
Outstanding Intern, Norman Chassin Award | |
First Place, Internal Medicine Quiz Competition, University at Buffalo | |
Outstanding Outgoing Resident, William M. and Stanley A.Bukowski Award | |
Fellows Recognition Program, National Comprehensive Cancer Network | |
ASCO/AACR Workshop on Methods in Clinical Cancer Research, ASCO/AACR | |
Obrine-Weaver Award, Ohio State University | |
Pelotonia Postdoctoral Award, Ohio State University - James Cancer Center | |
Young Investigator Award, American Society of Clinical Oncology | |
Scientific Career Development Retreat, Conquer Cancer Foundation | |
NCI/CTEP Career Development LOI | |
Integrated Translational Workshop, Cold Spring Harbor Laboratory and SWOG | |
Top 1% provider nationally for patient care |
Professional Memberships
Selected Publications
Peer-Reviewed Articles
- Meric-Bernstam F, Yuca E, Evans KW, Zhao M, Maejima T, Karibe T, Raso MG, Tang X, Zheng X, Rizvi YQ, Akcakanat A, Scott SS, Wang B, Byers LA, Tripathy D, Okajima D, Damodaran S. Anti-tumor activity and biomarker analysis for TROP2-antibody drug conjugate Datopotamab deruxtecan in patient-derived breast cancer xenograft models. Clin Cancer Res None(None):None, 2024. PMID: 39585341.
- Yam C, Patel M, Hill HA, Sun R, Bassett RL Jr, Kong E, Damodaran S, Koenig KB, Abouharb S, Saleem S, Bisen AK, Murthy RK, Ramirez DL, Rauch GM, Adrada BE, Candelaria RP, Wang X, Mittendorf EA, Thompson AM, White JB, Ravenberg EE, Clayborn AR, Ding QQ, Booser DJ, Oke O, Brewster AM, Hortobagyi GN, Ibrahim NK, Litton JK, Valero V, Arun BK, Tripathy D, Chang JT, Chen K, Korkut A, Moulder SL, Huo L, Lim B, Ueno NT. Targeting the Epidermal Growth Factor Receptor Pathway in Chemotherapy-Resistant Triple-Negative Breast Cancer: A Phase II Study. Cancer Res Commun 4(10):2823-2834, 2024. PMID: 39356138.
- Bardia A, Krop IE, Kogawa T, Juric D, Tolcher AW, Hamilton EP, Mukohara T, Lisberg A, Shimizu T, Spira AI, Tsurutani J, Damodaran S, Papadopoulos KP, Greenberg J, Kobayashi F, Zebger-Gong H, Wong R, Kawasaki Y, Nakamura T, Meric-Bernstam F. Datopotamab Deruxtecan in Advanced or Metastatic HR+/HER2- and Triple-Negative Breast Cancer: Results From the Phase I TROPION-PanTumor01 Study. J Clin Oncol 42(19):JCO2301909, 2024. e-Pub 2024. PMID: 38652877.
- Lim B, Seth S, Yam C, Huo L, Fujii T, Lee J, Bassett Jr, R, Nasser S, Ravenberg L, White JB, Clayborn A, Guerra G, Litton J, Damodaran S, Layman RM, Valero V, Tripathy D, Lewis MT, Dobrolecki LE, Lei JT, Candelaria RP, Arun BK, Rauch GM, Zhao L, Zhang J, Ding Q, Symmans WF, Chang J, Thompson A, Moulder S, Ueno NT. Phase 2 study of neoadjuvant enzalutamide and paclitaxel for luminal androgen receptor-enriched TNBC. Cell Reports Medicine 5(6), 2024. PMID: 38838676.
- Basho RK, Zhao L, White JB, Huo L, Bassett RL, Mittendorf EA, Thompson A, Litton JK, Ueno N, Arun B, Lim B, Valero V, Tripathy D, Zhang J, Adrada BE, Santiago L, Ravenberg E, Seth S, Yam C, Moulder SL, Damodaran S. Comprehensive analysis identifies variability in PI3K pathway alterations in triple-negative breast cancer subtypes. JCO Precis Oncol 8:e2300124, 2024. PMID: 38484209.
- Damodaran S, O'Sullivan C, Elkhanany A, Anderson IC, Barve M, Blau S, Cherian M, Peguero JA, Goetz MP, Plourde PV, Portman DJ, Moore HC. Open-label, phase II, multicenter study of lasofoxifene plus abemaciclib for treating women with metastatic ER+/HER2− breast cancer and an ESR1 mutation after disease progression on prior therapies. Annals of Oncology 34(12):1131-1140, 2023. PMID: 38072513.
- Goetz MP, Bagegni NA, Batist G, Brufsky AM, Cristofanilli M, Damodaran S, Daniel B, Fleming GF, Gradishar WJ, Graff SL, Grosse Perdekamp MT, Hamilton E, Lavasani S, Moreno-Aspitia A, O'Connor T, Pluard T, Rugo H, Sammons S, Schwartzberg L, Stover DG, Vidal GA, Wang G, Warner E, Yerushalmi R, Plourde PV, Portman DJ, Nili Gal-Yam E. Lasofoxifene versus fulvestrant for ER+/HER2− metastatic breast cancer with an ESR1 mutation. Annals of Oncology 34(12):1141-1151, 2023. PMID: 38072514.
- Goetz MP, Bagegni NA, Batist G, Brufsky A, Cristofanilli MA, Damodaran S, Daniel BR, Fleming GF, Gradishar WJ, Graff SL, Grosse Perdekamp MT, Hamilton E, Lavasani S, Moreno-Aspitia A, O’Connor T, Pluard TJ, Rugo HS, Sammons SL, Schwartzberg LS, Stover DG, Vidal GA, Wang G, Warner E, Yerushalmi R, Plourde PV, Portman DJ, Gal-Yam EN. Lasofoxifene versus fulvestrant for ER+/HER2- metastatic breast cancer with an ESR1 mutation: Results from the randomized, phase 2, ELAINE 1 trial. Annals of Oncology 34(12):1141-1151, 2023. PMID: None.
- Damodaran S, Sullivan CCO, Elkhanany A, Anderson IC, Barve M, Blau S, Cherian M, Peguero A, Goetz MP, Plourde PV, Portman DJ, Moore HCF. Open-label, phase 2, multicenter study of lasofoxifene plus abemaciclib for treating women with metastatic ER+/HER2- breast cancer and an ESR1 mutation after progression on prior therapies: ELAINE 2. Annals of Oncology 34(12):1131-1140, 2023. PMID: None.
- Saridogan T, Akcakanat A, Zhao M, Evans KW, Yuca E, Scott S, Kirby BP, Zheng X, Ha MJ, Chen H, Ng PKS, DiPeri TP, Mills GB, Rodon Ahnert J, Damodaran S, Meric-Bernstam F. Efficacy of futibatinib, an irreversible fibroblast growth factor receptor inhibitor, in FGFR-altered breast cancer. Sci Rep 13(1):20223, 2023. e-Pub 2023. PMID: 37980453.
- Navarro-Yepes J, Kettner NM, Rao X, Bishop CS, Bui TN, Wingate HF, Singareeka Raghavendra A, Wang Y, Wang J, Sahin AA, Meric-Bernstam F, Hunt KK, Damodaran S, Tripathy D, Keyomarsi K. Abemaciclib Is Effective in Palbociclib-Resistant Hormone Receptor-Positive Metastatic Breast Cancers. Cancer Res 83(19):3264-3283, 2023. PMID: 37384539.
- Zhao M, DiPeri TP, Raso MG, Zheng X, Rizvi YQ, Evans KW, Yang F, Akcakanat A, Roberto Estecio M, Tripathy D, Dumbrava EE, Damodaran S, Meric-Bernstam F. Epigenetically upregulating TROP2 and SLFN11 enhances therapeutic efficacy of TROP2 antibody drug conjugate sacitizumab govitecan. NPJ Breast Cancer 9(1):66, 2023. e-Pub 2023. PMID: 37567892.
- Nelson BE, Saleem S, Damodaran S, Somaiah N, Piha-Paul S, Moore JA, Yilmaz B, Ogbonna D, Karp DD, Dumbrava E, Tsimberidou AM, Hong DS, Rodon Ahnert J, Milton DR, Zheng X, Booser DJ, Ibrahim NK, Conley AP, Bhosale P, Rojas Hernandez CM, Tripathy D, Naing A, Meric-Bernstam F. Phase 1b study of combined selinexor and eribulin for the treatment of advanced solid tumors and triple-negative breast cancer. Cancer 129(14):2201-2213, 2023. e-Pub 2023. PMID: 37016732.
- Nelson BE, Saleem S, Damodaran S, Somiah N, Piha-Paul SA, Moore JA, Yilmaz B, Ogbonna D, Karp DD, Dumbrava EE, Tsimberidou AM, Hong DS, Ahnert JR, Milton DR, Zheng X, Booser DJ, Ibrahim NK, Conley AP, Bhosale P, Hernandez CMR, Tripathy D, Naing A, Meric-Bernstam F. Phase 1b Study of the Combination of Selinexor and Eribulin in Treatment of Advanced Solid Tumors and Triple-Negative Breast Cancer. Cancer 129(14):2201-2213, 2023. PMID: None.
- Abuhadra N, Sun R, Yam C, Rauch GM, Ding Q, Lim B, Thompson AM, Mittendorf EA, Adrada BE, Damodaran S, Virani K, White J, Ravenberg E, Sun J, Choi J, Candelaria R, Arun B, Ueno NT, Santiago L, Saleem S, Abouharb S, Murthy RK, Ibrahim N, Sahin A, Valero V, Symmans WF, Litton JK, Tripathy D, Moulder S, Huo L. Predictive Roles of Baseline Stromal Tumor-Infiltrating Lymphocytes and Ki-67 in Pathologic Complete Response in an Early-Stage Triple-Negative Breast Cancer Prospective Trial. Cancers (Basel) 15(13), 2023. e-Pub 2023. PMID: 37444385.
- Abuhadra N, Sun R, Bassett RL, Huo L, Chang JT, Teshome M, Clayborn AR, White JB, Ravenberg EE, Adrada BE, Candelaria RP, Yang W, Ding Q, Symmans WF, Arun B, Damodaran S, Koenig KB, Layman RM, Lim B, Litton JK, Thompson A, Ueno NT, Piwnica-Worms H, Hortobagyi GN, Valero V, Tripathy D, Rauch GM, Moulder S, Yam C. Targeting chemotherapy resistance in mesenchymal triple-negative breast cancer: a phase II trial of neoadjuvant angiogenic and mTOR inhibition with chemotherapy. Invest New Drugs 41(3):391-401, 2023. e-Pub 2023. PMID: 37043123.
- Blau S, Peguero JA, Moore HCF, Anderson IC, Barve MA, Cherian MA, Elkhanany A, O'Sullivan CC, Moreno-Aspitia A, Plourde P, Gleich LL, Riesen K, Ezzati R, Degele M, Shulman M, Stempf SD, Sachse L, Iyer AA, Damodaran S, Cooney MM. Operational Metrics for the ELAINE 2 Study Combining a Traditional Approach With a Just-in-TIME Model. JCO Clin Cancer Inform 7, 2023. PMID: 37352479.
- Yam C, Mittendorf EA, Garber HR, Sun R, Damodaran S, Murthy RK, Ramirez D, Karuturi M, Layman RM, Ibrahim N, Rauch GM, Adrada BE, Candelaria RP, White JB, Ravenberg E, Clayborn A, Ding QQ, Symmans WF, Prabhakaran S, Thompson AM, Valero V, Tripathy D, Huo L, Moulder SL, Litton JK. A phase II study of neoadjuvant atezolizumab and nab-paclitaxel in patients with anthracycline-resistant early-stage triple-negative breast cancer. Breast Cancer Res Treat 199(3):457-469, 2023. e-Pub 2023. PMID: 37061619.
- Chen H, Ding Q, Khazai L, Zhao L, Damodaran S, Litton JK, Rauch GM, Yam C, Chang JT, Seth S, Lim B, Thompson AM, Mittendorf EA, Adrada B, Virani K, White JB, Ravenberg E, Song X, Candelaria R, Arun B, Ueno NT, Santiago L, Saleem S, Abouharb S, Murthy RK, Ibrahim N, Routbort MJ, Sahin A, Valero V, Symmans WF, Tripathy D, Wang WL, Moulder S, Huo L. PTEN in triple-negative breast carcinoma: protein expression and genomic alteration in pretreatment and posttreatment specimens. Ther Adv Med Oncol 15:17588359231189422, 2023. e-Pub 2023. PMID: 37547448.
- Irajizad E, Wu R, Vykoukai J, Murage E, Spencer R, Dennison JB, Moulder S, Ravenbert E, Lim B, Liitton J, Tripathy D, Valero V, Damodaran S, Rauch GM, Adrada B, Candelaria R White JB, Brewster A, Arun B, Long JP, Do KA, Hanash S, Fahrmann JF. Application of artificial intelligence to plasma metabolomics profiles to predict response to neoadjuvant chemotherapy in triple-negative breast cancer. Frontiers in Artificial Intelligence 5(876100), 2022. PMID: 36034598.
- Yam C, Abuhadra N, Sun R, Adrada BE, Ding QQ, White JB, Ravenberg EE, Clayborn AR, Valero V, Tripathy D, Damodaran S, Arun BK, Litton JK, Ueno NT, Murthy RK, Lim B, Baez L, Li X, Buzdar AU, Hortobagyi GN, Thompson AM, Mittendorf EA, Rauch GM, Candelaria RP, Huo L, Moulder SL, Chang JT. Molecular characterization and prospective evaluation of pathological response and outcomes with neoadjuvant therapy in metaplastic triple-negative breast cancer. Clin Cancer Res 28(13):2878-2889, 2022. e-Pub 2022. PMID: 35507014.
- Ha MJ, Singareeka Raghavendra A, Kettner NM, Qiao W, Damodaran S, Layman RM, Hunt KK, Shen Y, Tripathy D, Keyomarsi K. Palbociclib plus endocrine therapy significantly enhances overall survival of HR+/HER2- metastatic breast cancer patients compared to endocrine therapy alone in the second-line setting-a large institutional study. Int J Cancer 150(12):2025-2037, 2022. e-Pub 2022. PMID: 35133007.
- Andre F, Ismaila N, Allison KH, Barlow WE, Collyar DE, Damodaran S, Henry NL, Jhaveri K, Kalinsky K, Kuderer NM, Litvak A, Mayer EL, Pusztai L, Raab R, Wolff AC, Stearns V. Biomarkers for Adjuvant Endocrine and Chemotherapy in Early-Stage Breast Cancer: ASCO Guideline Update. J Clin Oncol 40(16):JCO2200069, 2022. e-Pub 2022. PMID: 35439025.
- Damodaran S, Zhao F, Deming DA, Mitchell EP, Wright JJ, Gray RJ, Wang V, McShane LM, Rubinstein LV, Patton DR, Williams PM, Hamilton SR, Suga JM, Conley BA, Arteaga CL, Harris LN, O'Dwyer PJ, Chen AP, Flaherty KT. Phase II Study of Copanlisib in Patients With Tumors With PIK3CA Mutations: Results From the NCI-MATCH ECOG-ACRIN Trial (EAY131) Subprotocol Z1F. Journal of Clinical Oncology 40(14):1552-1561, 2022. e-Pub 2022. PMID: 35133871.
- Abuhadra N, Sun R, Litton JK, Rauch GM, Yam C, Chang JT, Seth S, Bassett R, Lim B, Thompson AM, Mittendorf E, Adrada BE, Damodaran S, White J, Ravenberg E, Candelaria R, Arun B, Ueno NT, Santiago L, Saleem S, Abouharb S, Murthy RK, Ibrahim N, Sahin AA, Valero V, Symmans WF, Tripathy D, Moulder S, Huo L. Prognostic Impact of High Baseline Stromal Tumor Infiltrating Lymphocytes in the Absence of Pathologic Complete Response in Early-Stage Triple-Negative Breast Cancer. Cancers (Basel) 14(5), 2022. e-Pub 2022. PMID: 35267631.
- Yam C, Yen EY, Chang JT, Bassett RL, Al-Atrash G, Garber H, Huo L, Yang F, Philips AV, Ding QQ, Lim B, Ueno NT, Kannan K, Sun X, Sun B, Parra ER, Symmans WF, White JB, Ravenberg E, Seth S, Guerriero JL, Rauch GM, Damodaran S, Litton JK, Wargo JA, Hortobagyi GN, Futreal A, Wistuba II, Sun R, Moulder-Thompson S, Mittendorf EA. Immune Phenotype and Response to Neoadjuvant Therapy in Triple-Negative Breast Cancer. Clin Cancer Res 27(19):5365-5375, 2021. e-Pub 2021. PMID: 34253579.
- Musall BC, Abdelhafez AH, Adrada BE, Candelaria RP, Mohamed RMM, Boge M, Le-Petross H, Arribas E, Lane DL, Spak DA, Leung JWT, Hwang KP, Son JB, Elshafeey NA, Mahmoud HS, Wei P, Sun J, Zhang S, White JB, Ravenberg EE, Litton JK, Damodaran S, Thompson AM, Moulder SL, Yang WT, Pagel MD, Rauch GM, Ma J. Functional Tumor Volume by Fast Dynamic Contrast-Enhanced MRI for Predicting Neoadjuvant Systemic Therapy Response in Triple-Negative Breast Cancer. J Magn Reson Imaging 54(1):251-260, 2021. e-Pub 2021. PMID: 33586845.
- Akcakanat A, Zheng X, Cruz Pico CX, Kim TB, Chen K, Korkut A, Sahin A, Holla V, Tarco E, Singh G, Damodaran S, Mills GB, Gonzalez-Angulo AM, Meric-Bernstam F. Genomic, Transcriptomic, and Proteomic Profiling of Metastatic Breast Cancer. Clin Cancer Res 27(11):3243-3252, 2021. e-Pub 2021. PMID: 33782032.
- Yam C, Rauch GM, Rahman T, Karuturi M, Ravenberg E, White J, Clayborn A, McCarthy P, Abouharb S, Lim B, Litton JK, Ramirez DL, Saleem S, Stec J, Symmans WF, Huo L, Damodaran S, Sun R, Moulder SL. A phase II study of Mirvetuximab Soravtansine in triple-negative breast cancer. Invest New Drugs 39(2):509-515, 2021. e-Pub 2020. PMID: 32984932.
- Damodaran S, Sember QC, Arun BK. Clinical implications of breast cancer tumor genomic testing. Breast J 26(8):1565-1571, 2020. e-Pub 2020. PMID: 32696498.
- Pairawan S, Hess KR, Janku F, Sanchez NS, Mills Shaw KR, Eng C, Damodaran S, Javle M, Kaseb AO, Hong DS, Subbiah V, Fu S, Fogelman DR, Raymond VM, Lanman RB, Meric-Bernstam F. Cell-free Circulating Tumor DNA Variant Allele Frequency Associates with Survival in Metastatic Cancer. Clin Cancer Res 26(8):1924-1931, 2020. e-Pub 2019. PMID: 31852833.
- Litton JK, Scoggins ME, Hess KR, Adrada BE, Murthy RK, Damodaran S, DeSnyder SM, Brewster AM, Barcenas CH, Valero V, Whitman GJ, Schwartz-Gomez J, Mittendorf EA, Thompson AM, Helgason T, Ibrahim N, Piwnica-Worms H, Moulder SL, Arun BK. Neoadjuvant talazoparib for patients with operable breast cancer with a germline BRCA pathogenic variant. Journal of Clinical Oncology 38(5):JCO1901304, 2020. e-Pub 2019. PMID: 31461380.
- Ueno NT, Tahara RK, Fujii T, Reuben JM, Gao H, Saigal B, Lucci A, Iwase T, Ibrahim NK, Damodaran S, Shen Y, Liu DD, Hortobagyi GN, Tripathy D, Lim B, Chasen BA. Phase II study of Radium-223 dichloride combined with hormonal therapy for hormone receptor-positive, bone-dominant metastatic breast cancer. Cancer Med 9(3):1025-1032, 2020. e-Pub 2019. PMID: 31849202.
- Pairawan S, Hess K, Janku F, Sanchez N, Shaw K, Eng, C, Damodaran S, Javle M, Kaseb A, Hong, D, Subbiah V, Fu S, Fogelman D, Raymond V, Lanman R, Meric-Bernstam F. Cell-Free Circulating Tumor DNA Variant Allele Frequency Associates with 1Survival in Metastatic Cancer. Clinical Cancer Research, 2020. PMID: None.
- Ding Q, Chen H, Lim B, Damodaran S, Chen W, Tripathy D, Piha-Paul S, Luthra R, Meric-Bernstam F, Sahin AA. HER2 somatic mutation analysis in breast cancer: correlation with clinicopathological features. Hum Pathol 24(92):32-8, 2019. e-Pub 2019. PMID: 31351155.
- Meric-Bernstam F, Zheng X, Shariati M, Damodaran S, Wathoo C, Brusco L, Demirhan ME, Tapia C, Eterovic AK, Basho RK, Ueno NT, Janku F, Sahin A, Rodon J, Broaddus R, Kim TB, Mendelsohn J, Mills Shaw KR, Tripathy D, Mills GB, Chen K. Survival outcomes by TP53 mutation status in metastatic breast cancer. JCO Precis Oncol 2018, 2018. e-Pub 2018. PMID: 30035249.
- Datta J, Damodaran S, Parks H, Ocrainiciuc C, Miya J, Yu L, Gardner EP, Samorodnitsky E, Wing MR, Bhatt D, Hays J, Reeser JW, Roychowdhury S. Akt Activation Mediates Acquired Resistance to Fibroblast Growth Factor Receptor Inhibitor BGJ398. Mol Cancer Ther 16(4):614-624, 2017. e-Pub 2017. PMID: 28255027.
- Samorodnitsky E, Jewell BM, Hagopian R, Miya J, Wing MR, Lyon E, Damodaran S, Bhatt D, Reeser JW, Datta J, Roychowdhury S. Evaluation of Hybridization Capture Versus Amplicon-Based Methods for Whole-Exome Sequencing. Hum Mutat 36(9):903-14, 2015. e-Pub 2015. PMID: 26110913.
- Damodaran S, Miya J, Kautto E, Zhu E, Samorodnitsky E, Datta J, Reeser JW, Roychowdhury S. Cancer Driver Log (CanDL): Catalog of Potentially Actionable Cancer Mutations. J Mol Diagn 17(5):554-9, 2015. PMID: 26320871.
- Samorodnitsky E, Datta J, Jewell BM, Hagopian R, Miya J, Wing MR, Damodaran S, Lippus JM, Reeser JW, Bhatt D, Timmers CD, Roychowdhury S. Comparison of custom capture for targeted next-generation DNA sequencing. J Mol Diagn 17(1):64-75, 2015. PMID: 25528188.
- Zhao W, Damodaran S, Villalona-Calero MA. From single-gene to multiplex analysis in lung cancer, challenges and accomplishments: a review of a single institution's experience. Lung Cancer Manag 4(3):315-324, 2014. PMID: 25580159.
- Damodaran S, Majumder S, Ramaswamy R. Endocrine resistance: mechanisms and therapeutic targets. Clinical Investigation 3(7):681-690, 2013. PMID: None.
- Damodaran S, Olson EM. Targeting the human epidermal growth factor receptor 2 pathway in breast cancer. Hosp Pract (1995) 40(4):7-15, 2012. PMID: 23299030.
- Miecznikowski JC, Damodaran S, Sellers KF, Rabin RA. A comparison of imputation procedures and statistical tests for the analysis of two-dimensional electrophoresis data. Proteome Sci 8:66, 2010. e-Pub 2010. PMID: 21159180.
- Damodaran S, Wood TD, Nagarajan P, Rabin RA. Evaluating peptide mass fingerprinting-based protein identification. Genomics Proteomics Bioinformatics 5(3-4):152-7, 2007. PMID: 18267296.
- Damodaran S, Rabin RA. Minimizing variability in two-dimensional electrophoresis gel image analysis. OMICS 11(2):225-30, 2007. PMID: 17594240.
- Damodaran S, Dlugos CA, Wood TD, Rabin RA. Effects of chronic ethanol administration on brain protein levels: a proteomic investigation using 2-D DIGE system. Eur J Pharmacol 547(1-3):75-82, 2006. e-Pub 2006. PMID: 16978605.
- Vadivelu MK, Damodaran S Solomon J, Rajaseharan A. Distribution of ABO blood groups in acute leukaemias and lymphomas. Ann Hematol 83(9):584-7, 2004. e-Pub 2004. PMID: 15175895.
Invited Articles
- Damodaran S, Roychowdhury S. Genomics and Precision Cancer Medicine. Oncology & Hematology Review 11(2):145-6, 2015. PMID: None.
- Abuhadra N, Sun R, Yam C, Rauch GM, Ding Q, Lim B, Thompson AM, Mittendorf EA, Adrada B, Damodaran S, Virani K, White J, Sun J, Choi J, Candelaria R, Arun B, Ueno NT, Santiago L, Saleem S, Abouharb S, Murthy RK, Ibrahim NK, Sahin A, Valero V, Fraser Symmans W, Litton JK, Tripathy D, Moulder S, Huo L. Predictive role of baseline stromal tumor-infiltrating lymphocytes and Ki-67 for pathologic complete response in an early-stage triple-negative breast cancer prospective trial. None. PMID: None.
Other Articles
- Roy M, Teshome M, Damodaran S, Sahin AA, Khazai L, Arribas E, Candelaria RP, Scoggins ME, Lane DL, Giordano SH, Albarracin CT, Prieto VG, Nagarajan P Male Mammary Paget Disease: A Tale of 2 Contrasting Cases. Am J Dermatopathol 42(12):981-985, 2020. PMID: 33289978.
- Damodaran S, Mrozek E, Liebner D, Kendra K Focal takotsubo cardiomyopathy with high-dose interleukin-2 therapy for malignant melanoma. J Natl Compr Canc Netw 12(12):1666-70; quiz 1670, 2014. PMID: 25505207.
- Damodaran S, Bellavia T, Sait SN, Wang ES, Wetzler M, Khushalani NI Acute myeloid leukemia secondary to oxaliplatin treatment for esophageal cancer. Clin Colorectal Cancer 11(2):151-4, 2012. PMID: 22133502.
- Damodaran S Cocaine and beta-blockers: the paradigm. Eur J Intern Med 21(2):84-6, 2010. PMID: 20206876.
Editorials
- Damodaran S, Hortobagyi GN. Estrogen Receptor: A Paradigm for Targeted Therapy. Cancer Res 81(2021; 81:5396-8):5396-5398, 2021. PMID: 34725132.
- Damodaran S, Roychowdhury S. Genomics and Precision Cancer Medicine and Clinical Trial Design. Oncology & Hematology Review 11(2):145-6, 2017. PMID: None.
Abstracts
- S D, Cristofanilli MA, Goetz MP, O’Sullivan C, Riordan G, Rugo HS, Stover DG, Wander SA, Carroll D, Plourde PV, Portman DJ, Gal-Yam E. Baseline genomic alterations and the activity of lasofoxifene (LAS) plus abemaciclib (Abema) in patients with ER+/HER2- metastatic breast cancer (mBC): the ELAINE 2 study. San Antonio Breast Cancer Symposium, 2023. PMID: None.
- Damodaran S, Iwase T, Marx A, Yuan Y, Kai M, Willey JS, Meric-Bernstam F, Tripathy D, Barcenas CH, Lee J, Ueno NT. Phase 1b study of EZH1/2 inhibitor valemetostat in combination with trastuzumab deruxtecan in subjects with HER2 low/ultra-low/null metastatic breast cancer. San Antonio Breast Cancer Symposium, 2023. PMID: None.
- Vidula N, Damodaran S, Blouch EL, Horick N, Ruffle-Deignan NR, Bhave M, Shah AN, Varella L, Abramson V, Sparano J, Ellisen L, Alim I, Ostrer O, Rugo H, Bardia A. Phase II study of talazoparib, a PARP inhibitor, in somatic BRCA1/2 mutant metastatic breast cancer identified by cell-free DNA or tumor tissue genotyping. San Antonio Breast Cancer Symposium, 2023. PMID: None.
- Goetz MP, Wander SA, Bachelot T, Batist G, Cortes J, Cristofanilli MA, Curigliano G, Nonneville A, Gal-Yam EN, Jhaveri K, Ma C, Parsons HA, Rugo HS, Sammons SL, Stover DG, Twelves C, Bardai A, Plourde PV, Portman DJ, Damodaran S. Open-label, randomized, multicenter, phase 3, ELAINE 3 study of the efficacy and safety of lasofoxifene plus abemaciclib for treating locally advanced or ER+/HER2- metastatic breast cancer with an ESR1 mutation. San Antonio Breast Cancer Symposium, 2023. PMID: None.
- Damodaran S, Andre F, Unni N, Ferreira M, Giridhar K, Daniel BR, Colleoni M, Costa L, Bachelot T, O’Brien C, Wright GLS, Shimura M, Tomlinson G, Gil M, Turner NC. Final Results from the Phase 2, Open-Label FOENIX‑MBC2 Study: Efficacy and Safety of Futibatinib in Adult Patients with Locally Advanced/Metastatic HR+/HER2− Breast Cancer Harboring High-Level FGFR1 Gene Amplification. San Antonio Breast Cancer Symposium, 2023. PMID: None.
- Giordano A, Unni N, Damodaran S, Rugo HS, Crook T, Bachelot T, Piacentini F, Parra HS, Krop IE, Shimura M, Tomlinson G, Gil M, Turner NC, Andre F. Efficacy and Safety of Futibatinib in Patients with Locally Advanced/Metastatic Triple-Negative Breast Cancer Harboring FGFR2 Gene Amplification: Final Results from the Phase 2, Open-Label FOENIX-MBC2 Study. San Antonio Breast Cancer Symposium, 2023. PMID: None.
- Damodaran S, Plourde PV, Jenkins SN, Mayer P, Portman DJ, Goetz MP. Pharmacokinetics (PK) of lasofoxifene (LAS) monotherapy and combined with abemaciclib (Abema). San Antonio Breast Cancer Symposium, 2023. PMID: None.
- Damodaran S, Moore HCF, Anderson IC, Cherian MA, O’Sulllivan CC, Plourde PV, Portman DJ, Goetz MP. Lasofoxifene (LAS) plus abemaciclib (Abema) for treating ESR1-mutated ER+/HER2- metastatic breast cancer (mBC) after progression on prior therapies: ELAINE 2 study update. American Society of Clinical Oncology Annual Meeting, 2023. PMID: None.
- Abuhadra N, Sun R, Yam C, Rauch GM, Ding Q, Lim B, Thompson AM, Mittendorf EA, Adrada BE, Damodaran S, Virani K, White J, Ravenberg E, Sun J, Choi J, Candelaria R, Arun B, Ueno NT, Santiago L, Saleem S, Abouharb S, Murthy RK, Ibrahim N, Sahin A, Valero V, Symmans WF, Litton JK, Tripathy D, Moulder S, Huo L. Predictive Roles of Baseline Stromal Tumor-Infiltrating Lymphocytes and Ki-67 in Pathologic Complete Response in an Early-Stage Triple-Negative Breast Cancer Prospective Trial. Cancers 2023 15:3275, 2023. PMID: None.
- Mouabbi J, Meric-Bernstam F, Turova P, Chernyshov K, Kushnarev V, Kotlov N, Brown JH, Clayton P, Nomie K, Fowler N, Tripathy D, Damodaran S. Genomic characterization of the GATA3 mutational landscape in breast cancer. American Society of Clinical Oncology Annual Meeting, 2023. PMID: None.
- Vidula N, Damodaran S, Bhave MA, Rugo HS, Blouch EL, Ruffle-Deignan NR, Shah AN, Cristofanilli M, Abramson VG, Sparano JA, Ostrer H, Horick NK. Bardia Phase II study of a PARP inhibitor in somatic BRCA1/2 mutant metastatic breast cancer (MBC). American Society of Clinical Oncology Annual Meeting, 2023. PMID: None.
- Nelson BE, Saleem S, Damodaran S, Somaiah N, Piha-Paul S, Moore JA, Yilmaz B, Ogbonna D, Karp DD, Ileana Dumbrava E, Tsimberidou AM, Hong DS, Rodon Ahnert J, Milton DR, Zheng X, Booser DJ, Ibrahim NK, Conley AP, Bhosale P, Rojas Hernandez CM, Tripathy D, Naing A, Meric-Bernstam F. Phase 1b study of combined selinexor and eribulin for the treatment of advanced solid tumors and triple-negative breast cancer. American Cancer Society:1-13. e-Pub 2023. PMID: 37016732.
- Nelson BE, Janku F, Fu S, Dumbrava EI, Hong DS, Karp D, Naing A, Rodon J, Tsimberidou A, Amaria RN, Conley A, Damodaran S, Raghav KP, Kreider BL, Tung, D, Varterasian M, Khazaie K, Piha-Paul S. Phase Ib Study of Pembrolizumab in Combination with Intratumoral Injection of Clostridium novyi-NT in Patients with Advanced Solid Tumors. American Association for Cancer Research Annual Meeting, 2023. PMID: None.
- Damodaran S, Moore H, O’Sulllivan CC, Plourde PV, Riordan G, Sloane HS, Tripathy D, Carroll D, Portman D. Estrogen receptor 1 (ESR1) mutations in circulating tumor DNA (ctDNA) from patients with ER+/HER2- metastatic breast cancer (mBC) treated with lasofoxifene plus abemaciclib in the ELAINE 2 study. San Antonio Breast Cancer Symposium, 2022. PMID: None.
- Yam C, Li Z, Korkut A, Ma W, Kong E, Hill HA, Abbas H, Abouharb S, Adrada B, Arun BK, Barcenas CH, Bisen A, Booser D, Buzdar A, Candelaria R, Chen J, Clayborn A, b|Damodaran S, Ding Q, Garber H, Hortobagyi GN, Hunt KK, Ibrahim NH, Iheme A, Karuturi MS, Koenig K, Layman RM, Lee J, Litton JK, Mitchell M, Moscol G, Mouabbi J, Murthy RK, Oke O, Pohlmann P, Ramirez D, Ravenberg E, Saleem S, Teshome M, Valero V, White J, Williams M, Woodward W, Yajima C, Ueno NT, Chen K, Rauch G, Huo L, Tripathy D. Clinical and Molecular Characteristics of HER2-low/zero Early Stage Triple- Negative Breast Cancer. San Antonio Breast Cancer Symposium, 2022. PMID: None.
- Damodaran S, Liu D, Schwartz J, Valero V, Ramirez R, Saleem S, Ueno NT, Ibrahim NK, Karuturi MS, Murthy RK, Moulder S, Litton JK. A phase Ib trial of bintrafusp alfa and eribulin in patients with metastatic triple negative breast cancer (TNBC. San Antonio Breast Cancer Symposium, 2022. PMID: None.
- Meric-Bernstam F, Krop I, Juric D, Hamilton E, Spira AI, Mukohara T, Tsunoda T, Damodaran S, Greenberg J, Gu W, Kobayashi F, Zebger-Gong H, Kawasaki Y, Wong R, Bardia A. Phase 1 TROPION-PanTumor01 Study Evaluating Datopotamab Deruxtecan (Dato-DXd) in Unresectable or Metastatic Hormone Receptor–Positive/HER2–Negative Breast Cancer (BC). San Antonio Breast Cancer Symposium, 2022. PMID: None.
- Damodaran S, Plourde PV, Moore CF H, Anderson IC, Portman DJ. Open-label, phase 2, multicenter study of lasofoxifene (LAS) combined with abemaciclib (Abema) for treating pre- and postmenopausal women with locally advanced or metastatic ER+/HER2− breast cancer and an ESR1 mutation after progression on prior therapies. American Society of Clinical Oncology Annual Meeting, 2022. PMID: None.
- Blau S, Peguero JA, Moore CF H, Anderson IC, Barve MA, Cherian MA, Elkhanany A, O'Sullivan CCM, Moreno-Aspitia A, Gleich LL, Riesen K, Ezzati R, Degele M, Shulman M, Stempf S, Cooney MM, Damodaran S. Operational metrics for the ELAINE study combining a traditional approach with a just-in-time model. American Society of Clinical Oncology Annual Meeting, 2022. PMID: None.
- Blau S, Peguero J A, Moore CF H, Anderson IC, Barve MA, Cherian MA, Elkhanany A, O”Sullivan, CCM, Moreno-Aspitia A, Gleich LL, Riesen K, Ezzati R, Degele M, Shulman M, Stempf S, Cooney MM, Damodaran S. Operational metrics for the ELAINE II study combining a traditional approach with a just-in-time model. American Society of Clinical Oncology Annual Meeting, 2022. PMID: None.
- Nelson BE, Saleem S, Damodaran S, Somiah N, Piha-Paul SA, Moore JA, Yilmaz B, Karp DD, Dumbrava EE, Tsimberidou AM, Hong DS, Ahnert JR, Booser D, Ibrahim NK, Conley AP, Bhosale P, Hernandez CMR, Tripathy D, Naing A, Meric-Bernstam F. Phase Ib study of selinexor and eribulin combination in advanced solid tumors and triple-negative breast cancer. American Society of Clinical Oncology Annual Meeting, 2022. PMID: None.
- Damodaran S, Plourde PV, Moore CF H, Anderson IC, Portman DJ. Open-label, phase 2, multicenter stuy of lasofoxifene (LAS) combined with abemaciclib (Abema) for treating pre and postmenopausal women with locally advanced or metastatic ER+/HER2-breast cancer and an ESR1 mutation after progression on prior therapies. American Society of Clinical Oncology Annual Meeting, 2022. PMID: None.
- Zhao M, Diperi TP, Raso G, Rizvi YQ, Zheng X, Evans K, Akcakanat A, Yang F, Tripathy D, Dumbrava EI, Damodaran S, Meric-Bernstam F. Epigenetically upregulating TROP2 enhances therapeutic efficacy of TROP2 ADC sacitizumab govitecan. American Association for Cancer Research, 2022. PMID: None.
- Yuca E, Evans K, Akcakanat A, Raso G, Rizvi YQ, Yang F, Byers L, Damodaran S, Daisuke O, Meric-Bernstam F. Anti-tumor activity and biomarker analysis for datopotamab deruxtecan in breast cancer PDX models. American Association for Cancer Research, 2022. PMID: None.
- Navarro-Yepes J, Kettner NK, Bui T, Raghavendra AS, Rao X, Wang J, Sahin A, Damodaran S, Tripathy D, Hunt KK, Keyomarsi K. Mechanisms of acquired resistance to palbociclib reveals pathways of response to abemaciclib. American Association for Cancer Research, 2022. PMID: None.
- Minussi DC, Wang J, Schalck A, Yan Y, H-J W, Peng C, Hu M, Sei E, Edgerton M, Chen H, Contreras A, Hui D, Damodaran S, Kopetz S, Lim B, Navin N. Resolving clonal substructure from single cell genomic data in primary and metastatic tumors using CopyKit. American Association for Cancer Research, 2022. PMID: None.
- Raghavendra AS, Ha MJ, Kettner NM, Damodaran S, Layman R, Hunt KK, Shen Y, Tripathy D, Keyomarsi K. Palbociclib plus endocrine therapy significantly enhances overall survival of HR+/HER2- metastatic breast cancer patients compared to endocrine therapy alone - A large institutional study. San Antonio Breast Cancer Symposium, San Antonio, 2021. PMID: None.
- Elshafeey N, Hwang KP, Adrada EB, Candelaria RP, Boge M, Mahmoud RM, Hm C, Sun J, Yang W, Kotrotsu A, Musall BC, Son JB, Whitman GJ, Leung J, Le-Petross H, Santiago L, Lane DL, Scoggins ME, Spak DA, Guirguis MS, Patel MM, Perez F, Abdelhafez AH, White JB, Huo L, E# R, Peng W, Thompson A, Damodaran S, Tripathy D, Moulder S, Yam C, Pagel MD, Ma J, Rauch GM. Radiomics model based on magnetic resonance image compilation (MagIC) as early predictor of pathologic complete response to neoadjuvant systemic therapy in triple-negative breast cancer. San Antonio Breast Cancer Symposium, San Antonio, 2021. PMID: None.
- Damodaran S, Unni N, Giridhar KV, Daniel B, Howell S, Costa L, Ferreira M, Shimura M, Tomlinson G, Gil M, Turner N. Futibatinib in combination with fulvestrant in patients with metastatic breast cancer (MBC) harboring high-level FGFR1 amplification: Preliminary data from a phase 2 study. San Antonio Breast Cancer Symposium, San Antonio, 2021. PMID: None.
- Krop I, Juric D, Shimizu T, Tochler A, Spira A, Mukohara T, Lisberg A E, Kogawa T, Papadopoulos K P, Hamilton E, Damodaran S, Greenberg J, Gu W, Kobayashi F, Guevara F, Jikoh T, Kawasaki Y, Meric-Bernstam F, Bardia A. Datopotamab deruxtecan in advanced/metastatic HER2- breast cancer: Results from the phase 1TROPION-PanTumor01 study. San Antonio Breast Cancer Symposium, 2021. PMID: None.
- Vidula N, Blouch E, Basile E, Horick N, Ruffle-Deignan N R, Damodaran S, Moreno-Aspitia A, Bhave M, Shah A, Liu MC, Sparano J, Ostrer H, Rugo HS, Ellisen L, Bardia A. Phase II study of a PARP inhibitor in metastatic breast cancer with somatic BRCA1/2 mutations identified by cell-free DNA: Genotyping based clinical trial. San Antonio Breast Cancer Symposium, San Antonio, 2021. PMID: None.
- Saridogan T, Akcakanat A, Zhao M, Evans KW, Yuca E, Scott S, Kirby BP, Zheng X, Damodaran S. Efficacy of futibatinib, an irreversible fibroblast growth factor receptor (FGFR) inhibitor, in breast cancer models with FGFR alterations. San Antonio Breast Cancer Symposium, San Antonio, 2021. PMID: None.
- Bardia A, Juric D, Shimizu T, Tolcher A, Korim R, Spira A, Mukohara T, Lisberg AE, Togawa T, Krop I, Papadopoulos KP, Hamilton E, Damodaran S, Greenberg J, Gu W, Kobayashi F, Guevara F, Jikoh T, Kawasaki Y, Meric-Bernstam F. Datopotamab deruxtecan (Dato-DXd), a TROP2-directed antibody-drug conjugate (ADC), for triple-negative breast cancer (TNBC): Preliminary results from an ongoing phase I trial. European Society for Medical Oncology Virtual Congress, 2021. PMID: None.
- Yam C, Mittendorf EA, Sun R, Huo L, Damodaran S, Rauch GM, Candelaria RP, Adrada BE, Seth S, Symmans WF, Murthy RK, White J, Ravenberg E, Clayborn A, Prabhakaran S, Valero V, Thompson AM, Tripathy D, Moulder SL, Litton JK. Neoadjuvant atezolizumab (atezo) and nab-paclitaxel (nab-p) in patients (pts) with triple- negative breast cancer (TNBC) with suboptimal clinical response to doxorubicin and cyclophosphamide (AC). American Society of Clinical Oncology Annual Meeting, 2021. PMID: None.
- Vidula N, Blouch E, Horick NK, Basile E, Damodaran S, Liu MC, Shah AN, Moreno-Aspitia A, Rugo HS, Ellisen L, Bardia A. Phase II multicenter study of talazoparib for somatic BRCA1/2 mutant metastatic breast cancer. American Society of Clinical Oncology Annual Meeting, 2021. PMID: None.
- Abuhadra A, Chag C, Yam C, White J, Ravenberg E, Lim B, Ueno NT, Litton JK, Arun B, Damodaran S, Murthy RK, Ibrahim NK, Hortobagyi GN, Valero V, Tripathy D, Thompson A, Mittendorf EA, Huo L, Moulder SL, Jeng RR. The impact of gut microbial composition on response to neoadjuvant chemotherapy (NACT) in early-stage triple negative breast cancer (TNBC). American Society of Clinical Oncology Annual Meeting, 2021. PMID: None.
- Raghavendra AS, Kwiatkowski D, Damodaran S, Kettner NM, Ramirez DL, Gombos DS, Hunt K, Shen Y, Keyomarsi K, Tripathy D. Phase I safety and efficacy study of autophagy inhibition with hydroxychloroquine to augment the antiproliferative and biological effects of preoperative palbociclib plus letrozole for estrogen receptor-positive, HER2-negative metastatic breast cancer (MBC). American Society of Clinical Oncology, 2021. PMID: None.
- Damodaran S, Plourde P V, Tripathy D, Jenkins S N, Portman D J. An Open-label, Multicenter Study Evaluating the Safety of Lasofoxifene in Combination with Abemaciclib for the Treatment of Pre- and Postmenopausal Women with Locally Advanced or Metastatic ER+/HER2− Breast Cancer and have an ESR1 Mutation. San Antonio Breast Cancer Symposium, San Antonio TX, 2020. PMID: None.
- Abuhadra N, Yam C, Sun R, Huo L, White J, Ravenberg E, Adrada B, Sahin A, Litton J, Lim B, Ueno N T, Arun B, Tripathy D, Damodaran S, Murthy R, Valero V, Hortobagyi G, Ibrahim N, Thompson A, Lucci A, Mittendorf E, Moulder S, Chang J. Prospective evaluation of patients with metaplastic (Mp) triple negative breast cancer (TNBC): Molecular characteristics and outcomes with neoadjuvant therapy (NAT). San Antonio Breast Cancer Symposium, San Antonio, TX, 2020. PMID: None.
- Abuhadra N, Chang C, Yam C, Sun R, Huo L, White J, Ravenberg E, Litton J, Lim B, Ueno N T, Arun B, Tripathy D, Damodaran S, Murthy R, Valero V, Hortobagyi G, Ibrahim N, Thompson A, Mittendorf E, Moulder S, Jenq R. Prospective evaluation of the gut microbiome and response to neoadjuvant therapy (NAT) in early-stage triple negative breast cancer (TNBC). San Antonio Breast Cancer Symposium, San Antonio, TX, 2020. PMID: None.
- Damodaran S, Murthy R K, Nusrat M, Saigal B, Trager S C, Tripathy D, Meric-Bernstam F. Phase Ib/II trial of copanlisib in combination with trastuzumab and pertuzumab after induction treatment of HER2 positive metastatic breast cancer with PIK3CA mutation or PTEN mutation. San Antonio Breast Cancer Synmposium, 2020. PMID: None.
- Yam C, Alatrash G, E-Y Y, Garber H, Philips A V, Huo L, Yang F, Basset R L, Sun X, Cuentas E R, Symmans W F, Seth S, White J B, Rauch G M, Damodaran S, Litton J K, Wargo J A, Hortobagyi G N, Moulder S L, Mittendorf E A. Immune phenotype and response to neoadjuvant systemic therapy (NAST) in triple negative breast cancer (TNBC). American Society of Clinical Oncology, Annual Meeting, 2020. PMID: None.
- Lim B, Seth S, Huo L, Layman R M, Valero V, Thompson A M, White J B, Litton J K, Damodaran S, Candelaria R P, Arun B, Rauch G M, Murthy R K, Ding Q, Symmans W F, Zhao L, Zhang J, Tripathy D, Moulder S L, Ueno N T. Comprehensive profiling of androgen receptor-positive (AR+) triple-negative breast cancer (TNBC) patients (pts) treated with standard neoadjuvant therapy (NAT) +/- enzalutamide. American Society of Clinical Oncology, Annual Meeting, 2020. PMID: None.
- Dumbrava E, Damodaran S, Zheng X, Vukovic V, Pairawan S S, Hong D S, Piha-Paul S S, Ahnert J R, Pant S, Subbiah V, Yuan Y, Murthy R, Litton J K, Ferrari D M, Andreeff M, Tripathy D, Aivado M, Meric-Bernstam F. A phase Ib study of ALRN-6924 (MDM2/MDMX inhibitor) in combination with paclitaxel in wild- type (WT) TP53 metastatic solid tumors including estrogen receptor positive (ER+) breast cancer. American Society of Clinical Oncology, Annual Meeting, 2020. PMID: None.
- Basho R, Yam C, White J B, Zhao L, Huo L, Mittendorf E A, Thompson A M, Litton J K, Arun B, Lim B, Valero V, Tripathy D, Zhang J, Adrada B E, Santiago L, Ravenberg E, Moulder S L, Damodaran S. Incidence of PI3K pathway alteration and response to neoadjuvant therapy (NAT) in triple negative breast cancer (TNBC) subtypes. American Society of Clinical Oncology, Annual Meeting, 2020. PMID: None.
- Abuhadra N, Sun R, Litton J K, Rauch G M, Thompson A M, Lim B, Adrada B, Mittendorf E, Damodaran S, Pitpitan R, Arun B, White J, Ravenberg E, Santiago L, Sahin A, Murthy R, Ueno N T, Ibrahim N, Moulder S, Huo L. The immunomodulatory (IM) signature enhances prediction of pathologic complete response (pCR) to neoadjuvant therapy (NAT) in triple negative breast cancers (TNBC) with moderate stromal tumour infiltrating lymphocytes (sTIL). ESMO Breast Cancer Virtual Meeting, 2020. PMID: None.
- Garber H, Rauch G M, Adrada B, Candelaria R P, Mittendorf E A, Thompson A M, Litton J K, Damodaran S, Lim B, Arun B, Ueno N T, Valero V, Ibrahim N K, Murthy R K, Tripathy D, Piwnica-Worms H, Symmans W F, Huo L, Moulder S L. Residual cancer burden in patients with early stage triple negative breast cancer who progress on anthracycline-based neoadjuvant chemotherapy in an ongoing clinical trial (ARTEMIS). San Antonio Breast Cancer Symposium, San Antonio, 2019. PMID: None.
- Rauch G M, Abdelhafez A H, Musall B C, Hess K R, Son J B, Pagel M D, Hwang K, Candelaria R P, Santiago L, Whitman G J, Le-Petross H, Moseley T W, Arribas E, Lane D L, Scoggins M E, Spak D A, Leung J, Damodaran S, Lim B, Valero V, White J W, Thompson A M, Litton J K, Moulder S L, Ma J, Yang W T, Adrada B E. Radiomics of quantitative apparent diffusion coefficient (ADC) from fibroglandular tissue (FGT) for prediction of tumor infiltrating lymphocytes (TIL) levels and neoadjuvant chemotherapy treatment (NACT) response in triple negative breast cancer (TNBC). San Antonio Breast Cancer Symposium, San Antonio, 2019. PMID: None.
- Roy M, Ma J, Sahin A A, Damodaran S, Tetzlaff M T, Curry J L, Ciura A M, Ning J, Torres-Cabala C, Ivan D, Aung P P, Ross M I, Gershenwald J E, Davies M A, Prieto V G, Nagarajan P. Primary cutaneous melanoma of the breast in women. A retrospective study of 82 patients. San Antonio Breast Cancer Symposium, San Antonio, 2019. PMID: None.
- Damodaran S, Litton J K, Hess K R, Eppig C T, Grzegorzewski K, Meric-Bernstam F, Wistuba I, White J B, Rauch G M, Candelaria R P, Adrada B, Lim B, Moulder S L, Tripathy D. A Phase-2, Two-Cohort Trial of Neoadjuvant Nab-Paclitaxel and Alpelisib in Anthracycline Refractory Triple Negative Breast Cancer with PIK3CA or PTEN alterations. San Antonio Breast Cancer Symposium, San Antonio, 2019. PMID: None.
- Adrada B E, Abdelhafez A H, Musall B C, Hess K R, Son J B, Pagel M D, Hwang K, Candelaria R P, Santiago L, Whitman G J, Le-Petross H, Moseley T W, Arribas E, Lane D L, Scoggins M E, Spak D A, Leung J, Damodaran S, Lim B, Valero V, White J W, Thompson A M, Litton J K, Moulder S L, Ma J, Yang W T, Rauch G M. Quantitative apparent diffusion coefficient (ADC) radiomics of tumor and peritumoral regions as potential predictors of treatment response to neoadjuvant chemotherapy (NACT) in triple negative breast cancer (TNBC) patients. San Antonio Breast Cancer Symposium, San Antonio, 2019. PMID: None.
- Turner N C, Krop I E, Bardia A, Damodaran S, Martin M, Benhadji K A, He Yaohua H, Ptaszynski M, Arteaga C L. A phase 2 study of futibatinib (TAS-120) in metastatic breast cancers harboring fibroblast growth factor receptor (FGFR) amplifications (FOENIX-MBC2). San Antonio Breast Cancer Symposium, San Antonio, TX, 2019. PMID: None.
- Abuhadra N, Hess K R, Litton J K, Rauch G M, Thompson A M, Lim B, Adrada B, Mittendorf E A, Damodaran S, Candelaria R P, Arun B, Yang W T, Ueno N T, Santiago L, Murthy R K, Ibrahim N K, Sahin A S, Symmans W F, Huo L, Moulder S L. Serial TILs: Evaluating the role of mid-treatment tumor infiltrating lymphocytes (TIL) in predicting pathologic complete response (pCR) in early-stage triple negative breast cancer (TNBC). San Antonio Breast Cancer Symposium, San Antonio, 2019. PMID: None.
- Litton JK, Damodaran S, Wistuba II, Yang F, Contreras A, Tam A, Ojalvo L, Dussault I, Helberg C, Moulder S. Bintrafusp alfa (M7824) and eribulin mesylate in treating patients with metastatic triple negative breast cancer (TNBC)(NCT03579472). European Society of Medical Oncology, Barcelona, Spain, 2019. PMID: None.
- Abuhadra N, Hess KR, Litton JK, Rauch GM, Thompson AM, Lim B, Adrada BE, Mittendorf EA, Damodaran S, Candelaria RP, Arun B, Yang WT, Ueno NT, Santiago L, Murthy RK, Ibrahim NK, Sahin AA, Symmans WF, Moulder SL, Huo L. Beyond TILs: Predictors of pathologic complete response (pCR) in triple-negative breast cancer (TNBC) patients with moderate tumor-infiltrating lymphocytes (TIL) receiving neoadjuvant therapy. American Society of Clinical Oncology, Annual Meeting, Chicago, 2019. PMID: None.
- Seth S, Crespo J, Huo L, Thompson AM, Mittendorf EA, Hess KR, Litton JK, Rauch GM, Adrada BE, Damodaran S, Candelaria RP, Arun B, Yang WT, Santiago L, Murthy RK, Sahin AA, Symmans WF, Moulder SL, Ueno NT, Lim B. Evaluation of predictive biomarkers for AR therapy and to identify the LAR subtype of TNBC. American Society of Clinical Oncology, Annual Meeting, Chicago, 2019. PMID: None.
- Yam C, Raghavendra A, Hess K R, Adrada B, Candelaria R P, Damodaran S, Gilcrease M, Helgason T, Hortobagyi G N, Huo L, Layman R M, Lim B, Litton J K, Mittendorf E A, Murthy R K, Piwnica-Worms H, Rauch G, Santiago L, Symmans W F, Thompson A M, Tripathy D, Ueno N T, Valero V, Barcenas C H, Moulder S L, Yang W. Impact of serial biopsies in triple-negative breast cancer patients receiving neoadjuvant systemic therapy. San Antonio Breast Cancer Symposium, San Antonio, 2018. PMID: None.
- Damodaran S, Meric-Bernstam F, Hess K R, Litton J K, Hortobagyi G N, Raymond V, Lanman R, Ueno N T, Hamilton S, Wistuba I I, Valero V, Moulder S L, Tripathy D. INTERACT- INTegrated Evaluation of Resistance and Actionability using Circulating Tumor DNA in hormone receptor (HR) positive metastatic breast cancers (MBC). San Antonio Breast Cancer Symposium, San Antonio, 2018. PMID: None.
- Ueno N T, Tahara, R K, Reuben J M, Gao H, Saigal B, Fujii T, Lucci A, Ibrahim, N K, Damodaran S, Shen Y, Liu D D, Hortobagyi G N, Tripathy D, Lim B, Chasen B A. CTCs and SUV to predict the efficacy of the bone-specific radiopharmaceutical agent radium-223 dichloride combined with hormonal therapy for hormone receptor-positive bone-dominant breast cancer metastasis. San Antonio Breast Cancer Symposium, San Antonio, 2018. PMID: None.
- Litton JK, Moulder SL, Hess KRm Damodaran S, Rauch GM, Candelaria R, Adrada BE, Symmons F, Murthy RK, Helgason T, Clayborn A, Prabhakaran S, Valero V, Thompson AM, Mitterdorf EA. Neoadjuvant trial of nab-paclitaxel and atezolizumab (Atezo), a PD-L1 inhibitor, in patients (pts) with chemo-insensitive triple negative breast cancer (TNBC). European Society of Medical Oncology, Munich, Germany, 2018. PMID: None.
- Yam C, Seth S, Hess KR, Mittendorf EA, Murthy RK, Damodaran S, Helgason T, Huo L, Gilcrease MZ, Chang JT, Moulder SL. Impact of clinical, morphologic and molecular characteristics on response to neoadjuvant systemic therapy (NAST) in metaplastic breast cancer (MpBC). European Society of Medical Oncology, Munich, Germany, 2018. PMID: None.
- Ueno N T, Tahara, R K, Saigal B, Fujii T, Reuben J M, Gao H, Lucci A, Ibrahim, N K, Damodaran S, Shen Y, Liu D D, Hortobagyi G N, Tripathy D, Lim B, Chasen B A. Phase II study of Ra-223 combined with hormonal therapy and denosumab for treatment of hormone receptor-positive breast cancer with bone-dominant metastasis. American Society of Clinical Oncology, Annual Meeting, Chicago, 2018. PMID: None.
- Litton J K, Scoggins M, Hess K R, Adrada B, Barcenas C H, Murthy R K, Damodaran S, DeSnyder S M, Brewster A M, Thompson A M, Ibrahim, N K, Moulder S L, Schwartz-Gomez J, Mittendorf E A, Arun B. Neoadjuvant talazoparib (TALA) for operable breast cancer patients with a BRCA mutation (BRCA+). American Society of Clinical Oncology, Annual Meeting, Chicago, 2018. PMID: None.
- Yam C, Hess K R, Litton J K, Yang W T, Santiago L, Candelaria R P, Mittendorf E A, Murthy R K, Damodaran S, Helgason T, Huo L, Thompson A M, Huang M L, Arribas, E A, Lane D L, Rauch G M, Adrada B E, Gilcrease M Z, Moulder S L. Impact of metaplastic histology (MpBC) in triple-negative breast cancer (TNBC) patients (pts) receiving neoadjuvant systemic therapy (NAST). American Society of Clinical Oncology, Annual Meeting, Chicago, 2018. PMID: None.
- Pairawan S S, Hess K R, Janku F, Sanchez N S, Eng C, Damodaran S, Javle M M, Kaseb A O, Hong D S, Subbiah V, Fu S, Fogelman D R, Raymond V M, Lanman R B, Meric-Bernstam F. Cell-free circulating tumor DNA somatic alteration burden and its impact on survival in metastatic cancer. American Society of Clinical Oncology, Annual Meeting, Chicago, 2018. PMID: None.
- Moulder S L, Hess K R, Candelaria R P, Santiago L, Adrada B, Yang W T, Gilcrease M Z, Huo L, Stauder M C, Arun B, Layman R, Murthy R K, Damodaran S, Ueno N T, Thompson A M, Lim B, Mittendorf E A, Litton J K, Symmans W F. Precision neoadjuvant therapy (P-NAT): A planned interim analysis of a randomized, TNBC enrolling trial to confirm molecular profiling improves survival (ARTEMIS). American Society of Clinical Oncology, Annual Meeting, Chicago, 2018. PMID: None.
- Yam C, Huo L, Hess K R, Litton J K, Yang W, Piwnica-Worms H, Mittendorf E A, Ueno N T, Lim B, Murthy R K, Damodaran S, Helgason T, Huo L, Thompson A M, Santiago L, Candelaria R P, Rauch G, Adrada B, Symmans W F, Gilcrease M, Moulder S L. Androgen Receptor (AR) Positivity is Associated with Nodal Disease in Triple Negative Breast Cancer (TNBC). San Antonio Breast Cancer Symposium, San Antonio, 2017. PMID: None.
- Tahara, R K, Fujii T, Saigal B, Ibrahim, N K, Damodaran S, Barcenas C H, Murray J L, Chasen B A, Shen Y, Liu D D, Hortobagyi G N, Tripathy D, Ueno N T. Phase II study of the feasibility and safety of radium-223 dichloride in combination with hormonal therapy and denosumab for the treatment of patients with hormone receptor-positive breast cancer with bone-dominant metastasis. San Antonio Breast Cancer Symposium, San Antonio, 2017. PMID: None.
- Yam C, Fornage, B D, Santiago L, Candelaria R P, Adrada B, Rauch G, Hess K R, Litton J K, Piwnica-Worms H, Mittendorf E A, Ueno N T, Lim B, Murthy R K, Damodaran S, Helgason T, Huo L, Thompson A M, Gilcrease M, Symmans W F, Moulder S, Yang W. Risk of Needle-Track Seeding with Serial Ultrasound Guided Biopsies in Triple Negative Breast Cancer (TNBC). San Antonio Breast Cancer Symposium, San Antonio, 2017. PMID: None.
- Damodaran S, Symmans F, Helgason T, Mittendorf E A, Tripathy D, Hess K, Litton J, Moulder. A Phase II Trial Of Mirvetuximab Soravtansine In Patients With Localized Triple-Negative Breast Cancer (TNBC) With Tumors Predicted Insensitive To Standard Neoadjuvant Chemotherapy (NACT) Including A Lead-In Cohort To Establish Activity In Patients With Metastatic TNBC. European Society of Medical Oncology, Congress, Madrid, Spain, 2017. PMID: None.
- Yam C, Hess K R, Litton J K, Yang W T, Piwnica-Worms H, Mittendorf E A, Ueno N T, Lim B, Murthy R K, Damodaran S, Helgason T, Huo L, Thompson A M, Gilcrease M, Santiago L, Candelaria R P, Rauch G, Adrada B, Symmans W F, Moulder S L. A Randomized, Triple Negative Breast Cancer Enrolling Trial To Confirm Molecular Profiling Improves Survival (ARTEMIS). American Society of Clinical Oncology, Annual Meeting, Chicago, 2017. PMID: None.
- Ding Q, Chen H, Lim B, Damodaran S, Chen W, Tripathy D, Piha-Paul S, Luthra R, Broaddus RR, Meric-Bernstam F, Sahin A. Somatic Mutation Analysis in Breast Cancer: Correlation with Clinicopathologic Features. USCAP Annual Meeting, 2017. PMID: None.
- Damodaran S, Dlugos CA, Rabin RA. Effects of chronic ethanol administration in zebrafish: proteomic study using 2-D DIGE. Sigma Xi Research Day, University at Buffalo, 2006. PMID: None.
- Damodaran S, Dlugos CA, Rabin RA. Effects of chronic ethanol administration in zebrafish: proteomic study using 2-D DIGE. Eastern Atlantic Student Research Forum, Miller School of Medicine, Miami, 2006. PMID: None.
- Damodaran S, Rabin RA. Mechanism of tolerance to ethanol: proteomic study in zebrafish. Pharmacology Sciences Day. University at Buffalo, 2004. PMID: None.
- Vadivelu MK, Damodaran S, Solomon J, Rajaseharan, A. Hospital based retrospective analysis of pediatric leukemias (acute) and lymphomas. 41st Annual National Student Research Forum, UTMB, Galveston, 2000. PMID: None.
- Damodaran S, Lu D, Schwartz-Gomez J, Valero V, Ramirez D, Saleem S, Ueno NT, Ibrahim NK, Karuturi M, Murthy RK, Moulder SL, Litton JK. Phase Ib trial of bintrafusp alfa and eribulin in patients with metastatic triple negative breast cancer (TNBC). San Antonio Breast Cancer Symposium 2022. PMID: None.
Book Chapters
- Tripathy D, Makhnoon S, Arun B, Sahin A, Kettner NM, Damodaran S, Keyomarsi K, Yang W, Hunt KK, Clemens M, Woodward WA, Mitchell MP, Layman R, Hobbs EA, Lim B, Dupuis M, Murthy R, Alhalabi O, Ibrahim N, Subbiah IS, Barcenas C. Neoplasms of the Breast. In: Holland-Freid Cancer Medicine. 10. Wiley Baker, 1361-1412, 2023.
- Damodaran S, Roychodhury S. Precision Cancer Medicine and Clinical Trial Design. In: Springer Nature. None. Springer Nature, 2019.
- Parker C, Damodaran S, Bland KI, K Hunt AK. The Breast. In: Schwartz’s Principles of Surgery. 11. None, 2019.
- Damodaran S, Tripathy D. Breast Cancer. In: Handbook of Targeted Cancer Therapy and Immunotherapy. None. None, 2018.
- Damodaran S, Berger MF, Roychowdhury S. Clinical Tumor Sequencing: Opportunities and Challenges for Precision Cancer Medicine. In: Am Soc Clin Oncol Educ Book. None. None, e175-82, 2015.
- Damodaran S, Cataland, S R. Excessive Bleeding with Normal Prothrombin Time, Partial Thromboplastin Time, and Platelet Count. In: The Coagulation Consult–A Case-Based Guide. None. Springer Press, 87-97, 2014.
Books (edited and written)
- Damodaran S, Tripathy D. Handbook of Targeted Cancer Therapy and Immunotherapy: Breast Cancer. Ed(s) None. None.
Grant & Contract Support
Title: | Overcoming Endocrine Insensitivity in ER-Positive Breast Cancer Patients |
Funding Source: | Cancer Prevention & Research Institute of Texas (CPRIT) |
Role: | Co-I |
Title: | Phase 1, Multicenter, Open-label, First-in-human Study of YL202 in Patients with Locally Advanced or Metastatic Non-small Cell Lung Cancer and Breast Cancer |
Funding Source: | MediLink Therapeutics |
Role: | PI |
Title: | A Ph 3, Open-label, Randomised Study of Datopotamab Deruxtecan (Dato-DXd) Vs. Investigators Choice of Chemo in Patients who are not Candidates for PD-1/PD-L1 Inhibitor Thx in 1st-line Locally Recurrent Inoperable or mTNBC (TROPION-Breast02) |
Funding Source: | Astra Zeneca |
Role: | PI |
Title: | 2018 ASPIRE Breast Cancer (by invite only) Evaluation of Talazoparib, a PARP inhibitor, for patients with somatic BRCA mutant metastatic breast cancer in a genotyping based clinical trial |
Funding Source: | Dana-Farber Cancer Institute |
Role: | PI |
Title: | An Open-label, Multicenter Study Evaluating the Safety of Lasofoxifene in Combination with Abemaciclib for the Treatment of Pre- and Postmenopausal Women with Locally Adv or Met ER+/HER2- Breast Cancer and have an ESR1 Mutation |
Funding Source: | Sermonix Pharmaceuticals |
Role: | PI |
Title: | A Phase-2, Two-Cohort Trial of Neoadjuvant Nab-Paclitaxel and Alpelisib in Anthracycline Refractory Triple Negative Breast Cancer with PIK3CA or PTEN alterations |
Funding Source: | Novartis Alliance |
Role: | PI |
Title: | Phase 2 study of TAS 120 in Metastatic Breast Cancers Harboring Fibroblast Growth Factor Receptor (FGFR) Amplifications |
Funding Source: | TAIHO PHARMACEUTICAL |
Role: | PI |
Title: | Core 1: Rational Combination Treatment Options to Reverse Resistance in Hormone Receptor Positive Breast Cancer Refractory to Standard Therapy |
Funding Source: | CPRIT |
Role: | Co-PI |
Title: | Southwest Early Clinical Trial Consortium |
Funding Source: | Southwest Early Clinical Trial Consortium |
Role: | Co-I |
Title: | STRATEGIC ALLIANCE: MDACC/Blueprint CDK2 Inhibitor Research Plan |
Funding Source: | BluePrint Medicines |
Role: | Co-PI |
Title: | ALRN-6924 and Paclitaxel in Treating Patients With Advanced, Metastatic, or Unresectable Solid Tumors |
Funding Source: | Gateway for Cancer Research |
Role: | Co-PI |
Title: | Texas Experimental Cancer Therapeutics Network - TEX CTN |
Funding Source: | NIH/NCI |
Role: | Co-PI |
Title: | BYLieve: Ph II, multi, Open Label,2-cohort, noncomparative study to assess efficacy/safety of alpelisib + fulvestrant or letrozole in pts with PIK3CA mutant, HR+, HER2- , advanced Breast Cancer and progressed on or after CDK 4/6 inhibitor treatments |
Funding Source: | Novartis |
Role: | PI |
Title: | ALLIANCE RCTS # 56600: Phase 2, Two-Cohort Trial of Neoadjuvant Nab-Paclitaxel and Alpelisib in Anthracycline Refractory TNBC with PIK3CA or PTEN alterations |
Funding Source: | ALLIANCE |
Role: | PI |
Title: | Integrated Evaluation of Resistance and Actionability using Circulating Tumor DNA in HR positive metastatic breast cancers |
Funding Source: | ALLIANCE |
Role: | PI |
Title: | Delineating the Evolution of Multi-Organ metastasis in Breast Cancer with Single Cell Genomics |
Funding Source: | Emerson Collective |
Role: | Co-I |
Title: | Rational Combination Treatment Options to Reverse Resistance in Hormone Receptor-Positive Breast Cancer Refractory to Standard Therapy |
Funding Source: | CPRIT |
Role: | Co-I |
Title: | EMD Serono A phase Ib trial of M7824 and eribulin in patients with metastatic triple negative breast cancer (TNBC) |
Funding Source: | EMD Serono Inc |
Role: | Co-PI |
Title: | University of Texas PDX Development and Trial Center |
Funding Source: | NIH/NCI |
Role: | Co-I |
Title: | Genomic and proteomic alterations mediate secondary resistance to fibroblast growth factor inhibition in cancers |
Funding Source: | ASCO Young Investigator Award |
Role: | PI |
Title: | A novel MELK-DKK1 pathway regulates stemness in Aggressive Breast Cancers |
Funding Source: | NIH/NCI |
Role: | Co-I |
Title: | Optimizing clinical response and characterizing resistance to TOP1 targeting in triple negative breast cancers |
Funding Source: | ASCO |
Role: | PI |
Title: | Phase 1b study of EZH1/2 inhibitor valemetostat in combination with trastuzumab deruxtecan in patients subjects with HER2 low/ultra-low/null low/null HER2-expressing metastatic breast cancer |
Funding Source: | Daichi Sankyo Co LTD |
Role: | PI |
Title: | A Phase 1/2a, Multicenter, Open-Label, Non-Randomized First in Human Study to Assess the Safety, Tolerability, Pharmacokinetics, and Preliminary Antitumor Activity of DB-1305 in Patients with Advanced/Metastatic Solid Tumors |
Funding Source: | Duality Biologics |
Role: | PI |
Title: | STRATEGIC ALLIANCE Agreement- Melanoma, Breast Cancer and Leukemia |
Funding Source: | Novartis Alliance |
Role: | Co-PI |
Title: | Genomic and proteomic alterations mediate secondary resistance to fibroblast growth factor inhibition in cancers |
Funding Source: | Pelotonia Postdoctoral Award |
Role: | PI |
Patient Reviews
CV information above last modified December 18, 2024