Victoria Serpas Higbie, M.D.
Department of Gastrointestinal Medical Oncology, Division of Cancer Medicine
Present Title & Affiliation
Primary Appointment
Assistant Professor, Gastrointestinal (GI) Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX
Dual/Joint/Adjunct Appointment
Assistant Professor, Gastrointestinal (GI) Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX
Education & Training
Degree-Granting Education
| 2015 | The University of Texas Southwestern Medical School, Dallas, Texas, US, MD |
| 2011 | Louisiana State University, Baton Rouge, Louisiana, US, Biological Sciences, BS |
Postgraduate Training
| 2019-2022 | Clinical Fellowship, Medical Oncology/Hematology, The University of Texas MD Anderson Cancer Center, Houston, Texas |
| 2015-2018 | Clinical Residency, Internal Medicine, Baylor College of Medicine, Houston, Texas |
Licenses & Certifications
| 2022 | Medical Oncology |
| 2022 | Hematology |
| 2018 | TMB |
| 2018 | Internal Medicine |
Experience & Service
Administrative Appointments/Responsibilities
Associate Patient Safety & Quality Officer, GI Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, 2025 - Present
Other Professional Positions
Chief Medical Resident, Baylor College of Medicine, Houston, TX, 2018 - 2019
Intramural Institutional Committee Activities
Co-Project Lead, Pharmacogemonics Project, The University of Texas MD Anderson Cancer Center, 2026 - Present
Working Group Lead, DPYD Pre-Treatment Testing Multidisciplinary Working Group, The University of Texas MD Anderson Cancer Center, 2025 - Present
Extramural Institutional Committee Activities
Colorectal Medical Oncology Representative, GI Service Line- Early Onset GI Malignancy Task Force, The University of Texas MD Anderson Cancer Center, 2026 - Present
Chair, Colorectal Cancer Multidisciplinary Conference, The University of Texas MD Anderson Cancer Center, 2025 - Present
Program Co-Lead, Young Onset Colorectal Cancer Program, The University of Texas MD Anderson Cancer Center, 2023 - Present
Honors & Awards
| 2020 | Merit Award Recipient, ASCO GI Cancers Symposium |
| 2018 - 2019 | Chief Medical Resident, Baylor College of Medicine |
| 2017 - 2018 | First Place Research Presentation, Texas SE Regional ACP Associate's Day |
| 2016 | Best Poster in Category, ESMO Congress |
| 2016 | Travel Grant, European Society of Medical Oncology |
Professional Memberships
Selected Presentations & Talks
Regional Presentations
- 2023. Early Onset Colorectal Cancer. Invited. Cancer Advocacy Group of Louisiana. New Orleans, LA, US.
Selected Publications
Peer-Reviewed Articles
- Lim, M, Grandhi, N, Shah, P, Raghav, KS, Serpas Higbie, V, Morelli, MP, Pedersen, KS, Kalyan, A, Salem, ME, Huey, RW, Shen, JY, Wang, H, Wang, H, Vinocha, A, Thomas, J, Wolff, RA, Overman, MJ. A retrospective analysis of taxane-based chemotherapy in small bowel adenocarcinoma. Oncologist 31(5), 2026. e-Pub 2026. PMID: 41871440.
- Pellatt, AJ, Bent, AH, Hornstein, N, Parseghian, C, Huey, RW, Raghav, KS, Morris, VK, Overman, MJ, Morelli, MP, Willis, JA, Le, PH, Shen, JY, Kee, BK, Eluri, M, Serpas Higbie, V, Alfaro-Munoz, KD, Aziz, KE, Kell, R, Sun, R, Kopetz, S, Dasari, NV. Phase II Trial of TAS-102 in Colorectal Cancer Patients With Circulating Tumor DNA-Defined Minimal Residual Disease After Adjuvant Therapy. JCO Precision Oncology 9, 2025. e-Pub 2025. PMID: 40669021.
- Shah, P, Raghav, KS, Serpas Higbie, V, Pedersen, KS, Kalyan, A, Salem, ME, Huey, RW, Shen, JY, Wang, H, Wang, H, Vinocha, A, Thomas, J, Wolff, RA, Overman, MJ. A retrospective analysis of taxane-based chemotherapy in small bowel adenocarcinoma (SBA). Journal of Clinical Oncology 43:e16479-e16479, 2025. e-Pub 2025.
- Grewal, K, Pant, S, Hu, I, Eluri, M, An, AW, Serpas Higbie, V, Huey, RW, Kasab, A, Javle, M, Lee, S. CLO25-099. Journal of the National Comprehensive Cancer Network : JNCCN 23(35), 2025. e-Pub 2025. PMID: 40154395.
- Yousef, M, Yousef, A, Chowdhury, S, Fanaeian, M, Knafl, M, Peterson, J, Zeineddine, MA, Alfaro, KD, Zeineddine, F, Goldstein, D, Hornstein, N, Dasari, NV, Huey, RW, Johnson, B, Serpas Higbie, V, Bent, AH, Kee, BK, Lee, MS, Morelli, MP, Morris, VK, Halperin, DM, Overman, MJ, Parseghian, C, Vilar Sanchez, E, Wolff, RA, Raghav, KS, White, MG, Uppal, A, Sun, R, Wang, W, Kopetz, S, Willis, JA, Shen, JY. Molecular, Socioeconomic, and Clinical Factors Affecting Racial and Ethnic Disparities in Colorectal Cancer Survival. JAMA Oncology 10(11), 2024. e-Pub 2024. PMID: 39264607.
- Beck, EJ, Sherry, AD, Florez, MA, Kouzy, R, Abi Jaoude, J, Lin, TA, Miller, AM, Passy, AH, Kupferman, GS, Patel, RR, Chino, F, Serpas Higbie, V, Parseghian, C, Overman, MJ, Minsky, B, Thomas, CR, Tang, C, Msaouel, P, Ludmir, EB. Secondary Endpoint Utilization and Publication Rate among Phase III Oncology Trials. Cancer Research Communications 4(8):2183-2188, 2024. e-Pub 2024. PMID: 39099199.
- Stemmer A, Margalit O, Serpas V, Strauss G, Thomas J, Shah P, Tau N, Levanon K, Shacham-Shmueli E, Kopetz S, Overman M, Boursi B. Immunotherapy in mismatch repair-deficient metastatic colorectal cancer - Outcome and novel predictive markers. Eur J Cancer 198:113495, 2024. e-Pub 2024. PMID: 38157568.
- Simmons, K, Thomas, J, Ludford, K, Willis, JA, Serpas Higbie, V, Raghav, KS, Johnson, B, Dasari, NV, Kee, BK, Parseghian, C, Lee, MS, Le, PH, Morelli, MP, Shen, JY, Bent, AH, Vilar Sanchez, E, Wolff, RA, Kopetz, S, Overman, MJ, Morris, VK. Sustained Disease Control in Immune Checkpoint Blockade Responders with Microsatellite Instability-high Colorectal Cancer after Treatment Termination. Cancer Research Communications 3(12):2510-2517, 2023. e-Pub 2023. PMID: 38085001.
- Gonzalez-Delgado, R, Munoz, NM, Carlos-Alcalde, W, Cho, MS, Lee, H, Jin, J, Serpas Higbie, V, Gorlova, OY, Sheth, RA, Afshar-Kharghan, V. Role of circulating mitochondria in venous thrombosis in glioblastoma. Journal of Thrombosis and Haemostasis 21(8):2202-2212, 2023. e-Pub 2023. PMID: 37178770.
- Serpas Higbie V, Rogers J, Hwang H, Qiao W, Xiao L, Dasari A, Mola-Rudd K, Morris VK, Wolff RA, Raghav K, Huey R, Parseghian C, Willis J, Kopetz S, Overman MJ, Johnson B. Antibiotic exposure does not impact immune checkpoint blockade response in MSI-H/dMMR metastatic colorectal cancer: a single center experience. Oncologist 27(11):952-957, 2022. e-Pub 2022. PMID: 35946836.
- Bhamidipati, D, Colina, A, Hwang, H, Wang, H, Katz, MH, Fournier, KF, Serpas Higbie, V, Thomas, J, Sun, R, Wolff, RA, Raghav, KS, Overman, MJ. Metastatic small bowel adenocarcinoma. ESMO Open 6(3), 2021. e-Pub 2021. PMID: 33940348.
- Bhamidipati D, Colina A, Hwang H, Wang H, Katz M, Fournier K, Serpas V, Thomas J, Sun R, Wolff RA, Raghav K, Overman MJ. Metastatic small bowel adenocarcinoma: role of metastasectomy and systemic chemotherapy. ESMO Open 6(3):100132, 2021. e-Pub 2021.
- Serpas VJ, Raghav KP, Halperin DM, Yao J, Overman MJ. Discrepancies in endpoints between clinical trial protocols and clinical trial registration in randomized trials in oncology. BMC Med Res Methodol 18(1):169, 2018. e-Pub 2018.
Abstracts
- Serpas V, Rogers J, Xiao L, Rola-Mudd K, Dasari A, Kee B, Overman M, Johnson B. Impact of antibiotic exposure on the efficacy of immune checkpoint blockade in MSI-H metastatic CRC. ASCO Gastrointestinal Cancer Symposium, San Francisco, CA, 2020. e-Pub 2020.
- Serpas V, Singh Raghav KP, Varadhachary GR, Wolff RA, Overman MJ. A retrospective study of anti-EGFR antibody therapy in small bowel adenocarcinoma. ASCO 2018 36, 2018. e-Pub 2018.
Patient Reviews
CV information above last modified July 22, 2026