Wei Wang, M.D., Ph.D.
Department of Hematopathology, Division of Pathology-Lab Medicine Div
Present Title & Affiliation
Primary Appointment
Assistant Professor, Department of Hematopathology, Division of Pathology/Lab Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX
Education & Training
Degree-Granting Education
| 2007 | Wake Forest University School of Medicine, Winston-Salem, NC, USA, PHD, Cancer Biology |
| 2001 | Shandong University School of Medicine, Jinan, CHN, MS, Human Anatomy, Histology and Embryology |
| 1998 | Shandong University School of Medicine, Jinan, CHN, MD, Medicine |
Postgraduate Training
| 2014-2016 | Hematopathology Fellow, The University of Texas MD Anderson Cancer Center, Houston, TX |
| 2010-2014 | Clinical Residency, Wake Forest University Baptist Medical Center, Winston-Salem, NC |
| 2007-2010 | Postdoctoral Research Fellow, Wake Forest University Baptist Medical Center, Winston-Salem, NC |
Board Certifications
| 2015 | The American Board of Pathology, Pathology - Hematology |
| 2014 | The American Board of Pathology, Pathology - Anatomic and Clinical |
Experience & Service
Academic Appointments
Fellow, Department of Hematopathology, Division of Pathology/Lab Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, 2014 - 2016
Pathology Resident, Department of Pathology, Wake Forest University Baptist Medical Center, Winston Salem, NC, 2010 - 2014
Postdoctoral Research Fellow, Department of Cancer Biology, Wake Forest University School of Medicine, Winston Salem, NC, 2007 - 2010
Honors & Awards
| 2016 | The Kimberly Patterson Endowed Fellowship in Leukemia Research Award, The University of Texas MD Anderson Cancer Center |
| 2016 | Platform Presentation / 1st Place, Texas Society of Pathologists, 95th Annual Meeting |
| 1993 | Medical Student Scholarship, Shandong University School of Medicine |
Selected Publications
Peer-Reviewed Articles
- Quesada AE, Medeiros LJ, Desai PA, Lin P, Westin JR, Hawsawi HM, Wei P, Tang G, Seegmiller AC, Reddy NM, Yin CC, Wang W, Xu J, Miranda RN, Zuo Z, Li S. Increased MYC copy number is an independent prognostic factor in patients with diffuse large B-cell lymphoma. Mod Pathol. e-Pub 2017. PMID: 28776574.
- Pina-Oviedo S, Wang W, Vicknair E, Manning JT, Medeiros LJ. Follicular lymphoma with hyaline-vascular Castleman disease-like follicles and CD20 positive follicular dendritic cells. Pathology 49(5):544-547, 2017. e-Pub 2017. PMID: 28689633.
- Wang W, Wang S, Medeiros LJ, Khoury JD. Response to Dr. Bain's comment on our review article: Pure Erythroid Leukemia. Am J Hematol. e-Pub 2017. PMID: 28707397.
- Montenegro-Garreaud X, Miranda RN, Reynolds A, Tang G, Wang SA, Yabe M, Wang W, Fang L, Bueso-Ramos CE, Lin P, Medeiros LJ, Lu X. Myeloproliferative neoplasms with t(8;22)(p11.2;q11.2)/BCR-FGFR1: a meta-analysis of 20 cases shows cytogenetic progression with B-lymphoid blast phase. Hum Pathol 65:147-156, 2017. e-Pub 2017. PMID: 28551329.
- Gong Z, Medeiros LJ, Cortes JE, Zheng L, Khoury JD, Wang W, Tang G, Loghavi S, Luthra R, Yang W, Kantarjian HM, Hu S. Clinical and prognostic significance of e1a2 BCR-ABL1 transcript subtype in chronic myeloid leukemia. Blood Cancer J 7(7):e583, 2017. e-Pub 2017. PMID: 28708130.
- Salem A, Loghavi S, Tang G, Huh YO, Jabbour EJ, Kantarjian H, Wang W, Hu S, Luthra R, Medeiros LJ, Khoury JD. Myeloid neoplasms with concurrent BCR-ABL1 and CBFB rearrangements: A series of 10 cases of a clinically aggressive neoplasm. Am J Hematol. e-Pub 2017. PMID: 28253536.
- Wang W, Wang SA, Medeiros LJ, Khoury JD. Pure erythroid leukemia. Am J Hematol 92(3):292-296, 2017. e-Pub 2017. PMID: 28006859.
- Chen Z, Medeiros LJ, Kantajian HM, Zheng L, Gong Z, Patel KP, Xiong H, Wang W, Cortes JE, Hu S. Differential depth of treatment response required for optimal outcome in patients with blast phase versus chronic phase of chronic myeloid leukemia. Blood Cancer J 7(2):e521, 2017. e-Pub 2017. PMID: 28157214.
- Gong Z, Zheng L, Tang Z, Chen Z, Wang W, Bai S, Tang G, Jeffrey Medeiros L, Hu S. Role of complexity of variant Philadelphia chromosome in chronic myeloid leukemia in the era of tyrosine kinase inhibitor therapy. Ann Hematol. e-Pub 2016. PMID: 27915425.
- Wang W, Chen Z, Hu Z, Yin CC, Li S, Bai S, Bueso-Ramos CE, Medeiros LJ, Hu S. Clinical significance of trisomy 8 that emerges during therapy in chronic myeloid leukemia. Blood Cancer J 6(11):e490, 2016. e-Pub 2016. PMID: 27813536.
- Gong Z, Xie W, Wang W, Chen Z, Xu J, Yuan J, Zhou Y, Wang D, Medeiros LJ, Hu S. T-lymphoid or T/myeloid blast phase of chronic myeloid leukemia in the era of tyrosine kinase inhibitor therapy: a report of 14 cases. Int J Lab Hematol. e-Pub 2016. PMID: 27863007.
- Hu Z, Medeiros LJ, Chen Z, Chen W, Li S, Konoplev SN, Lu X, Pham LV, Young KH, Wang W, Hu S. Mantle Cell Lymphoma With MYC Rearrangement: A Report of 17 Patients. Am J Surg Pathol. e-Pub 2016. PMID: 27776009.
- Hu Z, Sun Y, Wang W, Medeiros LJ, Kanagal-Shamanna R. Refractory Hairy Cell Leukemia-Variant. Am J Hematol. e-Pub 2016. PMID: 27727469.
- Chen Z, Shao C, Wang W, Zuo Z, Mou X, Hu SJ, DiGiuseppe JA, Zu Y, Medeiros LJ, Hu S. Cytogenetic landscape and impact in blast phase of chronic myeloid leukemia in the era of tyrosine kinase inhibitor therapy. Leukemia. e-Pub 2016. PMID: 27560111.
- Quesada AE, Huh YO, Wang W, Medeiros LJ, Thakral B. Anaplastic lymphoma kinase (ALK)-positive large B-cell lymphoma in a patient treated with azathioprine for ulcerative colitis. Pathology 48(5):513-5, 2016. e-Pub 2016. PMID: 27311871.
- Miao Y, Hu S, Lu X, D SL, Wang W, Medeiros LJ, Lin P. Double-hit Follicular Lymphoma with MYC and BCL2 Translocations: A Study of 7 Cases with a Review of Literature. Hum Pathol. e-Pub 2016. PMID: 27544800.
- Jain P, Verstovsek S, Wang W, Loghavi S, Torres HA, Estrov Z, Patel KP, Pemmaraju N. DNMT3A, TET2, and JAK2 mutations in polycythemia vera following long-term remission of secondary acute myeloid leukemia. Leuk Lymphoma 57(8):1969-73, 2016. e-Pub 2015. PMID: 26700872.
- Chen Z, Cortes JE, Jorgensen JL, Wang W, Yin CC, You MJ, Jabbour E, Kantarjian HM, Medeiros LJ, Hu S. Differential impact of additional chromosomal abnormalities in myeloid vs lymphoid blast phase of chronic myelogenous leukemia in the era of tyrosine kinase inhibitor therapy. Leukemia 30(7):1606-9, 2016. e-Pub 2016. PMID: 26837843.
- Wang W, Cortes JE, Tang G, Khoury JD, Wang S, Bueso-Ramos CE, DiGiuseppe JA, Chen Z, Kantarjian HM, Medeiros LJ, Hu S. Risk stratification of chromosomal abnormalities in chronic myelogenous leukemia in the era of tyrosine kinase inhibitor therapy. Blood 127(22):2742-50, 2016. e-Pub 2016. PMID: 27006386.
- Masarova L, Wang W, Newberry KJ, Kantarjian H, Verstovsek S. Complete hematologic, histomorphologic, cytogenetic, and molecular remission in a patient with JAK2- and IDH2-positive myelofibrosis. Blood. e-Pub 2016. PMID: 27325105.
- Wang W, Tang G, Kadia T, Lu X, Li Y, Huang L, Montenegro-Garreaud X, Miranda RN, Wang SA. Cytogenetic Evolution Associated With Disease Progression in Hematopoietic Neoplasms With t(8;22)(p11;q11)/BCR-FGFR1 Rearrangement. J Natl Compr Canc Netw 14(6):708-11, 2016. PMID: 27283163.
- Fang L, Hu Y, Wang W, Hu S, Zhang LI, Wang R. Development of multiple malignancies following long-term glucocorticoid therapy in a patient with leukocytoclastic vasculitis: A case report. Mol Clin Oncol 4(6):929-932, 2016. e-Pub 2016. PMID: 27284425.
- Chen Z, Wang W, Cortes JE, Liu E, Miranda RN, Zhao C, Yuan J, Lu X, Yang W, Ameri MD, Kantarjian HM, Medeiros LJ, Hu S. Differential clinical and prognostic impact of myeloid sarcoma vs medullary myeloid blast phase of chronic myelogenous leukemia in the era of tyrosine kinase inhibitor therapy. Blood Cancer J 6:e418, 2016. e-Pub 2016. PMID: 27152845.
- Wang W, Ali S, Tang Z, Miranda RN, Yang S, Medeiros LJ, Hu S. Constitutional pericentric inversion of chromosome 9 has no impact on survival in chronic myelogenous leukemia. Ann Hematol 95(4):657-9, 2016. e-Pub 2016. PMID: 26758271.
- Khandakar B, Wang W, Li S. Primary splenic red pulp diffuse large B-cell lymphoma with anaplastic features. Stem Cell Investig 3:9, 2016. e-Pub 2016. PMID: 27358901.
- Tang Z, Medeiros LJ, Yin CC, Wang W, Lu X, Young KH, Khoury JD, Tang G. Sex chromosome loss after allogeneic hematopoietic stem cell transplant in patients with hematologic neoplasms: a diagnostic dilemma for clinical cytogeneticists. Mol Cytogenet 9:62, 2016. e-Pub 2016. PMID: 27508005.
- Chen Z, Wang W, Verstovsek S, Cortes JE, Medeiros LJ, Hu S. Chronic myelogenous leukemia in patients with MPL or JAK2 mutation-positive myeloproliferative neoplasm. Int J Lab Hematol 37(6):e150-2, 2015. e-Pub 2015. PMID: 26086872.
- Liu H, Wang W, Tang G, Yin CC, Muzzafar T, Medeiros LJ, Hu S. Lymphomatous variant of hairy cell leukaemia: a distinctive presentation mimicking low-grade B-cell lymphoma. Histopathology 67(5):740-5, 2015. e-Pub 2015. PMID: 25809821.
- Wang W, Cortes JE, Lin P, Khoury JD, Ai D, Tang Z, Tang G, Jorgensen JL, Medeiros LJ, Hu S. Impact of trisomy 8 on treatment response and survival of patients with chronic myelogenous leukemia in the era of tyrosine kinase inhibitors. Leukemia 29(11):2263-6, 2015. e-Pub 2015. PMID: 25931274.
- Zhou X, Zhang J, Yun H, Shi R, Wang Y, Wang W, Lagercrantz SB, Mu K. Alterations of biomarker profiles after neoadjuvant chemotherapy in breast cancer: tumor heterogeneity should be taken into consideration. Oncotarget 6(34):36894-902, 2015. PMID: 26384297.
- Wang W, Cortes JE, Lin P, Beaty MW, Ai D, Amin HM, McDonnell TJ, Ok CY, Kantarjian HM, Medeiros LJ, Hu S. Clinical and prognostic significance of 3q26.2 and other chromosome 3 abnormalities in CML in the era of tyrosine kinase inhibitors. Blood 126(14):1699-706, 2015. e-Pub 2015. PMID: 26243778.
- Wang W, Xie W, Hu S. Cup-like blasts in B-lymphoblastic leukaemia. Br J Haematol 170(5):596, 2015. e-Pub 2015. PMID: 26132718.
- Chen Z, Wang W, Rich A, Tang G, Hu S. Myeloid sarcoma as the initial presentation of chronic myelogenous leukemia, medullary chronic phase in era of tyrosine kinase inhibitors: A report of 11 cases. Am J Hematol 90(8):E146-8, 2015. e-Pub 2015. PMID: 25960187.
- Wang W, Hu S, Lu X, Young KH, Medeiros LJ. Triple-hit B-cell Lymphoma With MYC, BCL2, and BCL6 Translocations/Rearrangements: Clinicopathologic Features of 11 Cases. Am J Surg Pathol 39(8):1132-9, 2015. PMID: 25828391.
- Wang W, Hu S. Neoplastic plasma cells mimic mature neutrophils in plasma cell myeloma with t(11;14)(q13;q32). Blood 125(18):2875, 2015. PMID: 26120642.
- Wang W, Tang G, Cortes JE, Liu H, Ai D, Yin CC, Li S, Khoury JD, Bueso-Ramos C, Medeiros LJ, Hu S. Chromosomal rearrangement involving 11q23 locus in chronic myelogenous leukemia: a rare phenomenon frequently associated with disease progression and poor prognosis. J Hematol Oncol 8:32, 2015. e-Pub 2015. PMID: 25888368.
- Jaitly V, Wang W, Hu S. Philadelphia chromosome-negative acute myeloid leukemia with 11q23/MLL translocation in a patient with chronic myelogenous leukemia. Stem Cell Investig 2:13, 2015. e-Pub 2015. PMID: 27358881.
- Wang W, Deng Z, Hatcher H, Miller LD, Di X, Tesfay L, Sui G, D'Agostino RB, Torti FM, Torti SV. IRP2 regulates breast tumor growth. Cancer Res 74(2):497-507, 2014. e-Pub 2013. PMID: 24285726.
- Wang W, Grier DD, Woo J, Ward M, Sui G, Torti SV, Torti FM, Beaty MW. Ferritin H is a novel marker of early erythroid precursors and macrophages. Histopathology 62(6):931-40, 2013. PMID: 23611361.
- Wang W, Pardee TS, Beaty MW. Subcutaneous panniculitis-like T-cell lymphoma with mesenteric involvement. Journal of Hematopathology 6(3):155-159, 2012.
- Wan M, Huang W, Kute TE, Miller LD, Zhang Q, Hatcher H, Wang J, Stovall DB, Russell GB, Cao PD, Deng Z, Wang W, Zhang Q, Lei M, Torti SV, Akman SA, Sui G. Yin Yang 1 plays an essential role in breast cancer and negatively regulates p27. Am J Pathol 180(5):2120-33, 2012. e-Pub 2012. PMID: 22440256.
- Han J, Seaman WE, Di X, Wang W, Willingham M, Torti FM, Torti SV. Iron uptake mediated by binding of H-ferritin to the TIM-2 receptor in mouse cells. PLoS One 6(8):e23800, 2011. e-Pub 2011. PMID: 21886823.
- Pinnix ZK, Miller LD, Wang W, D'Agostino R, Kute T, Willingham MC, Hatcher H, Tesfay L, Sui G, Di X, Torti SV, Torti FM. Ferroportin and iron regulation in breast cancer progression and prognosis. Sci Transl Med 2(43):43ra56, 2010. PMID: 20686179.
- Wang W, Di X, Torti SV, Torti FM. Ferritin H induction by histone deacetylase inhibitors. Biochem Pharmacol 80(3):316-24, 2010. e-Pub 2010. PMID: 20385107.
- Wang W, Knovich MA, Coffman LG, Torti FM, Torti SV. Serum ferritin: Past, present and future. Biochim Biophys Acta 1800(8):760-9, 2010. e-Pub 2010. PMID: 20304033.
- Jiao Y, Wilkinson J, Di X, Wang W, Hatcher H, Kock ND, D'Agostino R, Knovich MA, Torti FM, Torti SV. Curcumin, a cancer chemopreventive and chemotherapeutic agent, is a biologically active iron chelator. Blood 113(2):462-9, 2009. e-Pub 2008. PMID: 18815282.
- Zhang F, Wang W, Tsuji Y, Torti SV, Torti FM. Post-transcriptional modulation of iron homeostasis during p53-dependent growth arrest. J Biol Chem 283(49):33911-8, 2008. e-Pub 2008. PMID: 18819919.
- dos Santos CO, Dore LC, Valentine E, Shelat SG, Hardison RC, Ghosh M, Wang W, Eisenstein RS, Costa FF, Weiss MJ. An iron responsive element-like stem-loop regulates alpha-hemoglobin-stabilizing protein mRNA. J Biol Chem 283(40):26956-64, 2008. e-Pub 2008. PMID: 18676996.
- Blish KR, Wang W, Willingham MC, Du W, Birse CE, Krishnan SR, Brown JC, Hawkins GA, Garvin AJ, D'Agostino RB, Torti FM, Torti SV. A human bone morphogenetic protein antagonist is down-regulated in renal cancer. Mol Biol Cell 19(2):457-64, 2008. e-Pub 2007. PMID: 18032587.
- Wang W, Di X, D'Agostino RB, Torti SV, Torti FM. Excess capacity of the iron regulatory protein system. J Biol Chem 282(34):24650-9, 2007. e-Pub 2007. PMID: 17604281.
- Jiao Y, Wilkinson J, Christine Pietsch E, Buss JL, Wang W, Planalp R, Torti FM, Torti SV. Iron chelation in the biological activity of curcumin. Free Radic Biol Med 40(7):1152-60, 2006. PMID: 16545682.
Patient Reviews
CV information above last modified August 25, 2023