Xiaodong Zhang, Ph.D.
Department of Radiation Physics, Division of Radiation Oncology
Present Title & Affiliation
Primary Appointment
Professor, Department of Radiation Physics, Division of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX
Associate Faculty Member (Joint appointment), The University of Texas Graduate School of Biomedical Sciences, Houston, TX
Dual/Joint/Adjunct Appointment
Professor, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, TX
Education & Training
Degree-Granting Education
| 2001 | Ohio University, Athens, Ohio, US, Physics, Ph.D |
| 2001 | Ohio University, Athens, Ohio, US, Electrical Engineering and Computer Science, M.S |
| 1994 | Chinese Academy of Science, Lanzhou, US, Nuclear Physics, M.S |
| 1991 | University of Science and Technology of China, Hefei, US, Physics, BS |
Postgraduate Training
| 2001-2001 | Post-Doctoral Fellow, Computational Material Physics, Physical Science Research Lab, Motorola Inc.,, Tempe, Arizona |
Licenses & Certifications
| 2008 | American Board of Radiology |
| 2004 | Medical Physicist License awarded by the Texas Medical Board |
Experience & Service
Faculty Academic Appointments
Associate Professor, Department of Radiation Physics - Patient Care, The University of Texas MD Anderson Cancer Center, Houston, TX, 2014 - 2021
Regular Faculty Member, The University of Texas Graduate School of Biomedical Sciences, Houston, TX, 2012 - 2017
Assistant Professor, Department of Radiation Physics - Patient Care, The University of Texas MD Anderson Cancer Center, Houston, TX, 2006 - 2014
Instructor, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, TX, 2003 - 2006
Programmer Analyst II, Department of Radiation Physics - Patient Care, The University of Texas MD Anderson Cancer Center, Houston, TX, 2002 - 2003
Senior Scientist, Physical Science Research Lab, Motorola Inc, Tempe, AZ, 2001 - 2002
Staff Research Member, Institute of Modern Physics, Chinese Academy of Science, Lanzhou, 1994 - 1996
Administrative Appointments/Responsibilities
Co-Leader, Department of Radiation Oncology, The Center of Radiation Oncology Research Technology Work Group, Houston, TX, 2013 - 2018
Other Professional Positions
Adjunct Assistant Professor, Department of Physics, Ohio University, Athens, OH, 2009 - 2014
Extramural Institutional Committee Activities
Committee Member, External Advisory Committee for Clinical Trials and Biomarker Research for Massachusetts General Hospital Federal Share of Proton Beam Program Income, The University of Texas MD Anderson Cancer Center, 2015 - 2020
Editorial Activities
Associate Editor, Journal of Applied Medical Physics, 2015 - Present
Academic Editor, Cancers, 2014 - 2015
Honors & Awards
| 2014 | Proton Therapy Center - Medical Director Appreciation Award, Proton Therapy Center of UT MD Anderson Cancer Center |
| 2011 | Manuscript (Zhang et al. Phys. Med. Biol., 56, 7725, 2011) featured on Medical Physics Web, December 22, 2011, and in article by Jude Dineley, “Bragg curve model ramps clinic efficiency” December 22, |
| 2011 | Manuscript selected as the feature article of Physics in Medicine and Biology (Zhang X et al. Phys. Med. Biol. 56:7725, 2011), Institute of Physics |
| 2009 | Manuscript (Zhang et al. Int. J. Radiat. Oncol. Biol. Phys.., 77, 357-366, 2010) featured on Medical Physics Web, Oct 2, 2009, and in article by Tami Freeman, “IMPT preferable for advanced lung cancer” Oct 2, |
| 2008 | Leadership Award for Special Contributions in Research, The University of Texas MD Anderson Cancer Center |
| 2008 | Ohio University Spirit Award, Ohio University |
| 2008 | Robert M. Chamberlain Distinguished Mentor Award Nomination, The University of Texas MD Anderson Cancer Center |
| 2001 - 2002 | Silver Quill Awards for technical publications in Motorola, Motorola |
| 2000 | Nato Travel Award to Participate, Nato workshop on properties and applications of amorphous materials, Sec, Czech Repub. June 25-July 7 |
| 1999 | Fellowship in Condensed Matter and Surface Science Program (CMSS) of Ohio University, Ohio University |
| 1999 - 2001 | Graduate Fellowship from Motorola Inc. to investigate the transport of atomic scale device, Motorola Inc |
Professional Memberships
Selected Presentations & Talks
Local Presentations
- 2016. Proton Dose Calculation Algorithms. Conference. The University of Texas MD Anderson Cancer Center. Houston, TX, US.
- 2016. Advanced Optimization for Scanning Beam (Robust Optimization and Robust Analysis). Conference. The University of Texas MD Anderson Cancer Center. Houston, TX, US.
- 2016. Recent Development in Intensity Modulated Proton Therapy. Conference. The University of Texas MD Anderson Cancer Center. Houston, TX, US.
- 2011. Automatic Treatment Planning for IMRT, VMAT and IMPT. Conference. Radiation Physics Department, UTMDACC. Houston, TX, US.
- 2010. mdaccAutoPlan system. Conference. Radiation Physics Department, UT MDACC. Houston, TX, US.
- 2008. Proton Dose Calculation System. Conference. Radiation Physics Department, UTMDACC. Houston, TX, US.
- 2006. Strategies to treating mobile tumor using protons. Conference. Radiation Oncology Department, UTMDACC. Houston, TX, US.
Regional Presentations
- 2020. Particel/Proton Therapy Research Platform. Conference. MD Anderson, UT Austion. Houston, (Virtual), TX, US.
- 2020. Develop NTCP model for proton therapy. Conference. Loma Linda Proton Therapy Center. Loma Linda, CA, US.
- 2010. IMPT, IMRT and VMAT treatment plan and robustness comparison for prostate cancer. Conference. Winter Institute of Medical Physics, CO, US.
- 2009. Using IMPT to reduce penumbra margin for prostate cancer. Conference. Winter Institute of Medical Physics, CO, US.
National Presentations
- 2025. Physics Data for Multi-center IMPT vs. IMRT OPC Trial. Conference. Winter Institute of Medical Physicis. Brekenridge, CO, US.
- 2024. TREATMENT PLAN CHARACTERISTICS FOR A PHASE III MULTI-INSTITUTIONAL RANDOMIZED TRIAL COMPARING IMPT AND IMRT FOR OROPHARYNGEAL CANCER. Conference. PTOCOG62. Singapore City, Sigapore, SG.
- 2023. An autoplan approach to generate the IMPT/VMAT plan comparison report for proton therapy financial clearance. Conference. PTCOG61. Madrid, Madrid, ES.
- 2019. On the IMPT treatment planning based on LET/RBE information. Invited. Loma Linda Proton Therapy Center. Loma Linda, CA, US.
- 2015. Robust Optimization in Proton Therapy. Invited. ASTRO: Proton User Meeting. San Antonio, TX, US.
- 2014. Experience on the IMPT treatment planning of the challenging cases. Invited. PTCOG-NA. Houston, TX, US.
- 2014. Multi-Center Validation of automatic planning approach. Invited. Global Academic Program of UT MD Anderson Cancer Center. Seoul.
- 2013. The clinical implementation of IMPT for lung cancer: the physics consideration. Invited. AAPM. Indianapolis, IN, US.
- 2013. Physics Lecture - Dose Calculation and Optimization. Conference. The University of Texas MD Anderson Cancer Center. Houston, TX, US.
- 2012. Automatic Treatment Planning for IMRT, VMAT and IMPT. Invited. 2012 AAPM Annual Meeting. Charlotte, SC, US.
- 2012. An Automated and Optimal Treatment Planning Workflow For Intensity Modulated Proton Therapy. Conference. PTCOG 51. Seoul.
- 2011. Significant Improvement of Plan Quality, Delivery Efficiency and Plan Consistency by VMAT Combined with Automated Inverse Planning Algorithm for Stereotactic Body Radiation Therapy in Centrally/superiorly Located Stage I Non-Small-Cell Lung Cancer. Conference. 2011 Joint AAPM/COMPT Meeting. Vancouver, US.
- 2009. Lung IMRT Plan Design: MOO versus conventional inverse planning approach. Invited. New Directions in Multicriteria Planning for Radiation Therapy. Boston, MA, US.
- 2007. Treatment plan evaluation based on Monte Carlo Method. Invited. MD Anderson and Rice University Second Symposium on Computation Medical Physics. Houston, TX, US.
- 2002. Theoretical study of Sr Induced Reconstructions of Si Surfaces. Invited. American Physical Society Meeting. Indianapolis, IN, US.
- 2001. Theoretical Study of steps on the SrTiO3 (001) surface. Invited. Material Research Society Meeting. Boston, MA, US.
- 2001. Towards a First principle simulation and current-voltage character of atomistic metal oxide semiconductor structures. Invited. Motorola Computational Material Science Workshop. Tempe, AZ, US.
- 2000. ab-initio simulation of photo-structural change in amorphous selenium. Invited. American Physical Society Meeting. Minneapolis, MN, US.
- 1999. Evidence for Valence Alternation and a New Structural model for amorphous Selenium. Invited. APS Centennial Meeting. Atlanta, GA, US.
- 1998. Evidence for Valence Alternation in Amorphous Selenium. Invited. American Physical Society, Ohio Section Spring Meeting. Muncie, IN, US.
International Presentations
- 2019. Motion Management in Intensity Modulated Proton Therapy of PTCH. Invited. Institute of Nuclear Physics Poland. Karakov, PL.
- 2019. Improvement of Treatment Planning with AI and Log File. Invited. Hitachi. Tokyo, JP.
- 2019. IMPT treatment planning based on LET/RBE. Invited. The MD Anderson Radiation Oncology / Gilbert H. Fletcher Society. Tianjin, CN.
- 2017. Application of Artificial Intelligence in Radiation Therapy. Invited. CSTRO. Beijing, CN.
- 2016. The Application of Artificial Intelligence of Radiotherapy. Invited. Chengde Int'l Conference. Chengde, CN.
- 2016. Recent Research Developments in Proton Therapy in Proton Therapy Center of Houston. Invited. Recent Research Developments in Proton Therapy in Proton Therapy Center of Houston. Tianjing, CN.
- 2016. The mdaccAutoplan System. Conference. The mdaccAutoplan System. Tianjing, CN.
- 2016. Application of Machine Learning in the QA of Radiotherapy. Invited. CAMS. Beijing, CN.
- 2015. Clinical Usage of Knowledge Based Treatment Planning. Invited. 2015 AAMP Meeting. Anaheim, US.
- 2014. Clinical process of treatment planning, motion management and quality assurance on implementing intensity modulated proton therapy. Invited. 53rd Annual Meeting of Particle Therapy Co-Operative Group. Shanghai, CN.
- 2013. Autoplan and its application in random trial comparing proton and photon therapy. Invited. Tianjing Cancer Institute. Tianjin, CN.
- 2012. Automatic Treatment Planning. Invited. Tianjin Cancer Institute. Tianjin, CN.
- 2012. IMPT Robust Optimization. Invited. Zhang X. Beijing, CN.
- 2012. Automatic Treatment Planning for IMRT, VMAT and IMPT. Invited. Zhang X. Tianjin, CN.
- 2011. Toward a Thorough Evaluation of IMPT Plan Sensitivity to Uncertainties: Revisit the Worst-Case Analysis with An Exhaustively Sampling Approach. Conference. 2011 Joint AAPM/COMPT Meeting. Vancouver, CA.
- 2011. Using Beam Angle Optimization to Improve Treatment Plan Quality of Intensity Modulated Proton Therapy (IMPT) for Prostate Cancer. Conference. 2011 Joint AAPM/COMPT Meeting. Vancouver, CA.
- 2010. How could fixed beam intensity modulated radiotherapy exceed SmartArc. Conference. 52nd Annual Meeting of American Association of Physicists in Medicine. Philadelphia, US.
- 2010. Inverse Beam Angle Optimization in IMRT for Lung Cancer Patients. Conference. 52nd Annual Meeting of American Association of Physicists in Medicine. Philadelphia, US.
- 2009. Evaluating 4D Interplay Effects for Proton Scanning Beams in Lung Cancers. Conference. 51st Annual Meeting of American Association of Physicists in Medicine. Anaheim, US.
- 2008. A Hybrid Inverse Planning Algorithm of IMPT Optimization. Conference. 50th Annual Meeting of American Association of Physicists in Medicine. Houston, US.
- 2007. The good and not-so-good of Proton Therapy. Conference. 49th Annual Meeting of American Association of Physicists in Medicine. Minneapolis, US.
- 2006. Proton Lung Stereotactic Body Radiotherapy Treatment Method. Conference. 48th Annual Meeting of American Association of Physicists in Medicine. Orlando, US.
- 2006. Implementation of the Varian Eclipse System for Proton Therapy Treatment Planning. Conference. 48th Annual Meeting of American Association of Physicists in Medicine. Orlando, US.
- 2006. Thoracic Proton Treatment Planning Strategies Based On the 4D CT Information. Conference. 48th Annual Meeting of American Association of Physicists on Medicine. Orlando, US.
- 2005. Proton Treatment Planning for Mobile Lung Tumors. Conference. 47th Annual Meeting of American Association of Physicists in Medicine. Seattle, US.
- 2004. A Sensitivity guided algorithm to automate determination of objective function parameters for IMRT. Invited. 46th Annual meeting of the American Association of Physicists in Medicine. Pittsburgh, US.
- 2003. Speed and Convergence Properties of the gradient algorithms for IMRT optimization. Invited. 45th Annual meeting of American Association of Physicists in Medicine. San Diego, US.
- 2002. First-principles study of electron transport through atomistic metal-oxide-semiconductor structures. Invited. 2002 International Conference on Computational Nanoscience and Nanotechnology, US.
Formal Peers
- 2020. Particle/Proton therapy translational research platform. Invited. Austin, TX, US.
- 2020. Particle/Proton therapy translational research platform. Invited. Austin, TX, US.
- 2019. Present and Future Technology of Proton Therapy in MD Anderson Cancer Center. Invited. Miami, FL, US.
- 2019. Present and Future Technology of Proton Therapy in MD Anderson Cancer Center. Invited. Boston, MA, US.
- 2016. Recent Research Developments in Proton Therapy in the Proton Therapy Center of Houston. Invited, CN.
- 2014. Understanding the OS of lung cancer based on MD Anderson's results. Invited. Beijing, CN.
- 2013. The challenges and opportunities of proton therapy for lung cancer. Invited. Houston, TX, US.
- 2013. Physicist's role in bringing the best radiotherapy to cancer patients. Invited. Suzhou, US.
- 2012. Automatic Treatment Planning. Invited. Austin, TX, US.
- 2012. Physics Lecture: Robustness of IMPT Plans. Visiting. Houston, TX, US.
- 2011. Automatic Treatment Planning for IMRT, VMAT and IMPT. Invited. Mobile, AL, US.
- 2011. Automation in Radiation Therapy. Invited. Lanzhou, Gansu, CN.
- 2011. Automation in Radiation Therapy. Invited. Beijing, CN.
- 2011. IMPT optimization research. Visiting. Houston, TX, US.
- 2011. mdaccAutoPlan system. Invited. Tianjin, Tianjin, CN.
- 2011. An efficient dose calculation strategy for intensity modulated proton therapy. Invited. San Diego, CA, US.
- 2010. Automatic Treatment Planning for IMRT and VMAT. Invited. Houston, TX, US.
- 2009. Proton therapy dose calculation and optimization. Visiting. Helsinki, FI.
- 2009. Research Topics in Intensity Modulated Proton Therapy. Invited. Houston, TX, US.
- 2008. Radiation Treatment Planning Based on 4D CT. Invited. Athens, OH, US.
- 2004. Seminar, Optimization algorithms in intensity modulated radiation therapy. Invited. Athens, OH, US.
- 2002. Seminar, Building the Si-SrTiO3-GaAs Stack from first principle. Invited. Piscataway, NJ, US.
- 2002. Seminar, First-principles study of electron transport through atomistic metal-oxide-semiconductor structures. Invited. Durham, NC, US.
- 2002. Seminar, Building the Si-SrTiO3-GaAs Stack from first principle. Invited. Golden, CO, US.
- 2001. Seminar, Theoretical Studies of Structural, Electronic and Optical Properties of Amorphous Selenium and g-GeSe2 Surface. Invited. Athens, OH, US.
Grant & Contract Support
| Date: | 2024 - Present |
| Title: | OPC SURVIVOR: Optimizing OroPharyngeal Cancer SURVIVORship - Project 3: OPC-RAD (PI, Frank) |
| Funding Source: | NIH |
| Role: | Co-I |
| ID: | 1P01CA285249-01A1Project 3: OPC-RAD |
| Date: | 2021 - 2025 |
| Title: | Collaborative Research: SCH: Falcon: Privacy-Preserving, Personalized and Scalable Federated Analysis and Learning for Cancer Diagnosis and Radiation Oncology |
| Funding Source: | National Science Foundation (NSF) |
| Role: | Co-PI |
| Date: | 2021 - 2026 |
| Title: | Risk prediction and longitudinal assessment of cardiotoxicity and functional capacity trajectory in NSCLC patients |
| Funding Source: | NIH/NCI |
| Role: | Co-I |
| Date: | 2020 - 2020 |
| Title: | Mitigate the Cardiac Toxicity for Lung Cancer Patients based on Multi-Scale Personalized NTCP Model |
| Funding Source: | MD Anderson - RADIATION ONCOLOGY STRATEGIC INITIATIVES |
| Role: | PI |
| Date: | 2020 - 2021 |
| Title: | Particle/Proton therapy translational research platform |
| Funding Source: | The Oden Institute for Computational Engineering and Sciences (Oden Institute), The University of Texas MD Anderson Cancer Center (MD Anderson), and Texas Advanced Computing Center (TACC) |
| Role: | Principal Investigator-MDACC |
| Date: | 2020 - 2021 |
| Title: | Clinical Potential of a Monte Carlo-Based Biological Dose Optimization System for Intensity-Modulated Particle Therapy |
| Funding Source: | MD Anderson Cancer Center |
| Role: | Co-I |
| ID: | Institutional Research Grant |
| Date: | 2016 - 2018 |
| Title: | Effects of HPV status and fraction numbers on the relative biological effectiveness of proton beam therapy in head and neck cancer models |
| Funding Source: | MD Anderson |
| Role: | Co-I |
| ID: | IRG |
| Date: | 2016 - 2017 |
| Title: | Combining DNA damage repair—targeted therapy with proton, carbon ion, or photon radiotherapy to improve outcomes in prostate cancer and head and neck cancer |
| Funding Source: | Sister Institution Network Fund-MDACC |
| Role: | Co-I |
| Date: | 2014 - 2015 |
| Title: | Optimization of Delivery Sequence (ODS) for Intensity Modulated Proton Therapy (IMPT) of Lunc Cancer Patients |
| Funding Source: | UTMDACC-The Center for Radiation Oncology Research (CROR) |
| Role: | Co-I |
| ID: | N/A |
| Date: | 2014 - 2019 |
| Title: | Improving the clinical effectiveness and understanding of the biophysical basis - Core B: Clinical & Research Support at MDACC |
| Funding Source: | NIH/NCI |
| Role: | Co-I |
| ID: | 2U19CA021239-35 |
| Date: | 2014 - 2017 |
| Title: | Philips Pinnacle3 Proton Planning for IMPT Beta version |
| Funding Source: | Philips Medical System |
| Role: | PI |
| Date: | 2014 - 2016 |
| Title: | Minimizing dose uncertainty for spot scanning proton beam of moving tumors by optimization |
| Funding Source: | Varian Medical Systems |
| Role: | Co-I |
| Date: | 2013 - 2016 |
| Title: | Intensity Modulated Proton Therapy Treatment Planning Optimization Under Uncertainty |
| Funding Source: | National Science Foundation (NSF) |
| Role: | Co-PI |
| Date: | 2013 - 2015 |
| Title: | Knowledge-Based Intensity Modulated Proton Therapy Treatment Planning |
| Funding Source: | Varian Medical System |
| Role: | PI |
| Date: | 2012 - 2014 |
| Title: | Using the mdaccAutoPlan system to improve radiotherapy plan quality while reducing cost |
| Funding Source: | Sister Institution Network Fund-MDACC |
| Role: | PI |
| Date: | 2012 - 2013 |
| Title: | Large-scale parallelized 4D worst-case robust optimization for intensity modulated proton therapy |
| Funding Source: | UTMDACC Institutional Research Grant |
| Role: | Co-PI |
| Date: | 2012 - 2013 |
| Title: | Intensity Modulated Proton Therapy |
| Funding Source: | Sister Institution Network Fund-MDACC and DKFZ |
| Role: | Co-I |
| Date: | 2012 - 2013 |
| Title: | Evaluate Pinnacle Proton Dose Engine |
| Funding Source: | Philips |
| Role: | PI |
| Date: | 2011 - 2014 |
| Title: | Next Generation Radiotherapy Treatment Planning with Dynamical Machine Learning (pending) |
| Funding Source: | Cancer Prevention & Research Institute of Texas (CPRIT) |
| Role: | PI |
| ID: | Pending |
| Date: | 2010 - 2015 |
| Title: | Getting the Most Out of Intensity Modulated Proton Therapy |
| Funding Source: | NIH/NCI |
| Role: | Co-PI |
| ID: | 2R01-CA074043-12 |
| Date: | 2009 - 2011 |
| Title: | Advanced optimization techniques in Intensity Modulated Proton Therapy |
| Funding Source: | Rice University |
| Role: | Co-PI |
| Date: | 2008 - 2014 |
| Title: | Optimizing Proton Radiation Therapy |
| Funding Source: | NIH/NCI |
| Role: | Co-I |
| ID: | 2-P01CA021239 |
| Date: | 2008 - Present |
| Title: | Startup Fund |
| Funding Source: | UT MDACC |
| Role: | PI |
| Date: | 2006 - Present |
| Title: | Computational Scientist |
| Funding Source: | Varian Medical System |
| Role: | PI |
| Date: | 2005 - 2009 |
| Title: | Online Image-guided IMRT for Inter-Fractional Changes |
| Funding Source: | NIH/NCI |
| Role: | Co-I |
| ID: | R01-CA-74043 |
| Title: | Optimizing the Biological Effectiveness of Intensity-Modulated Proton Therapy |
| Funding Source: | NIH/NCI |
| Role: | Co-I |
Selected Publications
Peer-Reviewed Articles
- Frank, SJ, Busse, PM, Lee, JJ, Rosenthal, D, Hernandez, M, Swanson, DM, Garden, AS, Gunn, GB, Patel, SH, Snider, JW, Ma, DJ, Molitoris, JK, Lee, N, Parvathaneni, U, McDonald, MW, Kalman, NS, Lin, A, Mohammed, N, Henson, CE, Hyde, C, Bajaj, GK, Katz, SR, Dagan, R, Morrison, WH, Reddy, JP, Fuller, C, Shah, SJ, Phan, J, Chronowski, G, Mayo, LL, Sturgis, EM, Ferrarotto, R, Zhu, XR, Zhang, X, Wang, L, Hutcheson, KA, El-Naggar, AK, Moreno, AC, Lee, A, Spiotto, MT, Gross, N, Lai, SY, Liao, JJ, Paly, JJ, Liao, Z, Foote, RL, Bates, JE, Chambers, MS, Chun, SG, Kaiser, A, Lester, SC, Lukens, JN, McGee, LA, Neben-Wittich, MA, Nguyen, Q, Routman, DM, Schlembach, PJ, Skinner, H, Soike, MH, Rwigema, JM, Wiederhold, LR, Blanchard, P, Choi, I, Koong, A, Langendijk, H, Mohan, R, Carlson, BJ, Mapps, A, Sarmiento, JG, Teferra, MY, Bosch, WR, Followill, DS, Taylor, PA, Fuentes, SY, Ning, M, Toumazis, I, Wogan, CF, De Gracia, B, Fink, K, Grippin, A, Ma, J, Pettersen, EA, Sareyeldin, RM, Cronin, C, Muise, S, Johnson, M, Pyfferoen, K, Tranby, BN, Leonard, J, Watkin, S, Eggleston, C, Barrow, B, Wolcott, J, Antonio, J, Brand, J, Cleverdon, A, Drake, M, Peters, E, Small, C, Clark, K, Holder, R. Proton versus photon radiotherapy for patients with oropharyngeal cancer in the USA. The Lancet 407(10524):174-184, 2026. e-Pub 2026. PMID: 41391462.
- Liao, L, Xu, T, Chen, M, Su, TS, Sahoo, N, Zhu, X, Frank, SJ, Nguyen, Q, Liao, Z, Zhang, X. Evaluation of organ-specific relative biological effectiveness of proton therapy using radiation-induced pneumonitis as an endpoint. Clinical and Translational Radiation Oncology 56, 2026. e-Pub 2026. PMID: 41445933.
- Moreno, AC, Sahli, A, Johnson, FM, Sun, X, Barbon, CE, Rinsurongkawong, W, Song, W, Luciani, FM, Liang, H, Li, J, Liu, W, Lee, JJ, Frank, SJ, Lai, SY, Fuller, C, Hutcheson, KA, Fuller, C, Lee, J, Frank, S, Mohamed, AS, Peterson, CB, McMillan, H, Ma, J, Brock, K, Wang, L, Chambers, MS, Williams, MD, Naser, M, He, R, Shete, S, Zhang, X, Whinsenant, M. Stiefel MD Anderson OroPharynx cancer (MDA-OPC) cohort. BMJ open 15(11), 2025. e-Pub 2025. PMID: 41290309.
- Xinru Chen MS, PhD XZ, Ting Xu MD, PhD RM, PhD RL, Mei Chen MS, Rachel C Maguire BS, PhD YZ, Efstratios Koutroumpakis MD, Nicolas L Palaskas MD, Anita Deswal MD, PhD AA, Niedzielski PhD JS, Shete PhD SS, Court PhD LE, PhD JY, Zhongxing Liao MD. Radiation doses to cardiac substructures predict elevation in high-sensitivity cardiac troponin T (hs-cTnT) levels in radiotherapy for lung cancer. International Journal of Radiation Oncology*Biology*Physics. e-Pub 2025.
- Liao, Li, Xu, Ting, Chen, Mei, Su, Ting-Shi, Sahoo, Narayan, Zhu, Xiaorong, Frank, Steven J, Nguyen, Quynh-Nhu, Liao, Zhongxing, Xiaodong. Evaluation of Organ-Specific Relative Biological Effectiveness of Proton Therapy Using Radiation-Induced Pneumonitis as an Endpoint. Radiother Oncology. e-Pub 2025.
- Chen, X, Ding, Y, Weng, JK, Wu, CC, Zhao, Y, Sobremonte, A, Mohammedsaid, M, Xu, Z, Zhang, X, Niedzielski, JS, Shete, S, Court, LE, Liao, Z, Wang, J, Subashi, ED, Lee, PP, Yang, J. Deep Learning-Based Cardiac Chamber Segmentation in Magnetic Resonance-Guided Adaptive Radiation Therapy. Advances in Radiation Oncology 10(9), 2025. e-Pub 2025. PMID: 40808698.
- Wang, H, Alsanea, FM, Rhee, DJ, Zhang, X, Liu, W, Yang, J, Wen, Z, Zhao, Y, Williamson, TD, Hunter, R, Balter, PA, Briere, TM, Zhu, XR, Lee, A, Moreno, AC, Reddy, JP, Garden, AS, Rosenthal, D, Gunn, GB, Phan, J. Advanced External Beam Stereotactic Radiotherapy for Skull Base Reirradiation. Cancers 17(3), 2025. e-Pub 2025. PMID: 39941906.
- Guan, F, Bronk, LF, Kerr, M, Li, Y, Braby, LA, Sobieski, M, Wang, X, Zhang, X, Stephan, C, Grosshans, DR, Mohan, R. Interpreting the biological effects of protons as a function of physical quantity. Scientific reports 14(1), 2024. e-Pub 2024. PMID: 39448656.
- Chen, X, Zhao, Y, Baroudi, H, El Basha, MD, Daniel, A, Gay, SS, Yu, C, Wang, H, Phan, J, Choi, S, Goodman, C, Zhang, X, Niedzielski, JS, Shete, S, Court, LE, Liao, Z, Löfman, F, Balter, PA, Yang, J. Comparison of Vendor-Pretrained and Custom-Trained Deep Learning Segmentation Models for Head-and-Neck, Breast, and Prostate Cancers. Diagnostics 14(24), 2024. e-Pub 2024. PMID: 39767212.
- Liang, D, Vazquez, I, Gronberg, M, Zhang, X, Zhu, XR, Frank, SJ, Court, LE, Martel, MK, Yang, M. Deep learning-based statistical robustness evaluation of intensity-modulated proton therapy for head and neck cancer. Physics in medicine and biology 69(19), 2024. e-Pub 2024. PMID: 39241803.
- Sosa, A, Rooney, MK, Thames, HD, Sanders, JW, Swanson, DM, Choi, S, Nguyen, Q, Mok, H, Kuban, DA, Ron Zhu, X, Shah, SJ, Mayo, LL, Hoffman, K, Tang, C, McGuire, SE, Sahoo, N, Zhang, X, Lee, AK, Pugh, T, Mahmood, U, Davis, JW, Chapin, BF, Corn, P, Kudchadker, R, Ausat, N, Frank, SJ. Proton therapy toxicity outcomes for localized prostate cancer. Clinical and Translational Radiation Oncology 48, 2024. e-Pub 2024. PMID: 39188999.
- Hu, W, Zhang, J, Zhou, D, Xia, S, Pu, Xx, Cao, JZ, Zou, M, Mao, Z, Song, QB, Zhang, X. A comparison study of artificial intelligence performance against physicians in benign-malignant classification of pulmonary nodules. Oncologie 26(4):581-586, 2024. e-Pub 2024.
- Corrigan, KL, Xu, T, Sasaki, Y, Lin, R, Chen, AB, Welsh, JW, Lin, SH, Chang, JY, Ning, MS, Gandhi, S, O'Reilly, MS, Gay, CM, Altan, M, Lu, C, Cascone, T, Koutroumpakis, E, Sheshadri, A, Zhang, X, Liao, L, Zhu, XR, Heymach, JV, Nguyen, Q, Liao, Z. Survival outcomes and toxicity of adjuvant immunotherapy after definitive concurrent chemotherapy with proton beam radiation therapy for patients with inoperable locally advanced non-small cell lung carcinoma. Radiotherapy and Oncology 193, 2024. e-Pub 2024. PMID: 38311031.
- Chen, X, Mumme, R, Corrigan, KL, Mukai-Sasaki, Y, Koutroumpakis, E, Palaskas, NL, Nguyen, C, Zhao, Y, Huang, K, Yu, C, Xu, T, Daniel, A, Balter, PA, Zhang, X, Niedzielski, JS, Shete, S, Deswal, A, Court, LE, Liao, Z, Yang, J. Deep learning–based automatic segmentation of cardiac substructures for lung cancers. Radiotherapy and Oncology 191, 2024. e-Pub 2024. PMID: 38122850.
- Wang X, van Rossum PS, Chu Y, Hobbs BP, Grassberger C, Hong TS, Liao Z, Yang J, Zhang X, Netherton T, Mohan R, Lin SH. Severe Lymphopenia During Chemoradiation Therapy for Esophageal Cancer: Comprehensive Analysis of Randomized Phase 2B Trial of Proton Beam Therapy Versus Intensity Modulated Radiation Therapy. International Journal of Radiation Oncology* Biology* Physics 118(2):363-377, 2024. e-Pub 2024.
- Wang, X, van Rossum, P, Chu, Y, Hobbs, BP, Grassberger, C, Hong, TS, Liao, Z, Yang, J, Zhang, X, Netherton, T, Mohan, R, Lin, SH. Severe Lymphopenia During Chemoradiation Therapy for Esophageal Cancer. International Journal of Radiation Oncology Biology Physics 118(2):368-377, 2024. e-Pub 2024. PMID: 37652304.
- Chen, X, Weng, JK, Sobremonte, A, Lee, B, Hughes, N, Mohammedsaid, M, Zhao, Y, Wang, X, Zhang, X, Niedzielski, JS, Shete, S, Court, LE, Liao, Z, Lee, PP, Yang, J. Case report. Frontiers in Oncology 14, 2024. e-Pub 2024. PMID: 39351356.
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- Li Y, Niemela P, Liao L, Jiang S, Li H, Poenisch F, Zhu XR, Siljamaki S, Vanderstraeten R, Sahoo N, Gillin M, Zhang X. Selective Robust Optimization: a New Intensity-Modulated Proton Therapy Optimization Strategy. Med Phys 42(8):4840-4847, 2015. e-Pub 2015. PMID: 26233211.
- Pan HY, Jiang S, Sutton J, Liao Z, Chance WW, Frank SJ, Zhu XR, Li H, Fontanilla HP, Zhang X, Gomez DR. Early experience with intensity modulated proton therapy for lung-intact mesothelioma: a case series. Pract Radiat Oncol 5(4):e345-53, 2015. e-Pub 2015. PMID: 25572666.
- Holliday EB, Garden AS, Rosenthal DI, Fuller C, Morrison WH, Gunn G, Phan J, Beadle BM, Zhu XR, Zhang X, Hanna E, Glisson BS, Hutcheson KA, El-Naggar AK, Hong J, Hung T, Uzel EK, Lewis G, Frank SJ. Proton Therapy Reduces Treatment-Related Toxicities for Patients with Nasopharyngeal Cancer: A Case-Match Control Study of Intensity-Modulated Proton Therapy and Intensity-Modulated Photon Therapy. International Journal of Particle Therapy 2(1):19-28, 2015. e-Pub 2015.
- Li H, Zhang X, Park P, Liu W, Chang J, Liao Z, Frank S, Li Y, Poenisch F, Mohan R, Gillin M, Zhu R. Robust optimization in intensity-modulated proton therapy to account for anatomy changes in lung cancer patients. Radiotherapy and Oncology 114(3):367-372, 2015. e-Pub 2015.
- Cao, W, Lim, GJ, Li, Y, Zhu, XR, Zhang, X. Improved Beam Angle Arrangement in Intensity Modulated Proton Therapy Treatment Planning for Localized Prostate Cancer. Cancers 7(2):574-584, 2015. e-Pub 2015.
- Mackin D, Zhu XR, Poenisch F, Li H, Sahoo N, Kerr M, Holmes C, Li Y, Lii M, Wu R, Suzuki K, Gillin MT, Frank SJ, Grosshans D, Zhang X. Spot-Scanning Proton Therapy Patient Specific Quality Assurance: Results from 309 Treatment Plans. International Journal of Particle Physics 1(3):711-720, 2014. e-Pub 2014.
- Chang JY, Li H, Zhu XR, Liao Z, Zhao L, Liu A, Li Y, Sahoo N, Poenisch F, Gomez DR, Wu R, Gillin M, Zhang X. Clinical implementation of intensity-modulated proton therapy for thoracic malignancies. Int J Radiat Oncol Biol Phys 90(4):809-818, 2014. e-Pub 2014. PMID: 25260491.
- Cao W, Lim G, Liao L, Li Y, Jiang S, Li X, Li H, Suzuki K, Zhu XR, Gomez D, Zhang X. Proton energy optimization and reduction for intensity-modulated proton therapy. Phys Med Biol 59(21):6341, 2014. e-Pub 2014. PMID: 25295881.
- Kardar L, Li Y, Li X, Li H, Cao W, Chang JY, Liao L, Zhu RX, Sahoo N, Gillin M, Liao Z, Komaki R, Cox JD, Lim G, Zhang X. Evaluation and mitigation of the interplay effects of intensity modulated proton therapy for lung cancer in a clinical setting. Pract Radiat Oncol 4(6):e259-68, 2014. e-Pub 2014. PMID: 25407877.
- Frank SJ, Cox JD, Gillin M, Mohan R, Garden AS, Rosenthal DI, Gunn GB, Weber RS, Kies MS, Lewin JS, Munsell MF, Palmer MB, Sahoo N, Zhang X, Liu W, Zhu XR. Multifield Optimization Intensity Modulated Proton Therapy for Head and Neck Tumors: A Translation to Practice. Int J Radiat Oncol Biol Phys 89(4):846-853, 2014. e-Pub 2014. PMID: 24867532.
- Du W, Cho SH, Zhang X, Hoffman KE, Kudchadker RJ. Quantification of beam complexity in intensity-modulated radiation therapy treatment plans. Med Phys 41(2):021716, 2014. e-Pub 2014. PMID: 24506607.
- Li Y, Kardar L, Li X, Li H, Cao W, Chang JY, Liao L, Zhu RX, Sahoo N, Gillin M, Liao Z, Komaki R, Cox JD, Lim G, Zhang X. On the interplay effects with proton scanning beams in stage III lung cancer. Med Phys 41(2):021721, 2014. e-Pub 2014. PMID: 24506612.
- Zhu XR, Poenisch F, Li H, Zhang X, Sahoo N, Wu RY, Li X, Lee AK, Chang EL, Choi S, Pugh T, Frank SJ, Gillin MT, Mahajan A, Grosshans DR. A single-field integrated boost treatment planning technique for spot scanning proton therapy. Radiat Oncol 9(1):202, 2014. e-Pub 2014. PMID: 25212571.
- Li H, Liu W, Park P, Matney J, Liao Z, Chang J, Zhang X, Li Y, Zhu RX. Evaluation of the systematic error in using 3D dose calculation in scanning beam proton therapy for lung cancer. J Appl Clin Med Phys 15(5):4810, 2014. e-Pub 2014. PMID: 25207565.
- Li H, Park P, Liu W, Matney J, Liao Z, Balter P, Li Y, Zhang X, Li X, Zhu XR. Patient-specific quantification of respiratory motion-induced dose uncertainty for step-and-shoot IMRT of lung cancer. Med Phys 40(12):121712, 2013. e-Pub 2013. PMID: 24320498.
- Mackin D, Li Y, Taylor MB, Kerr M, Holmes C, Sahoo N, Poenisch F, Li H, Lii J, Amos R, Wu R, Suzuki K, Gillin MT, Zhu XR, Zhang X. Improving spot-scanning proton therapy patient specific quality assurance with HPlusQA, a second-check dose calculation engine. Med Phys 40(12):121708, 2013. e-Pub 2013. PMID: 24320494.
- Wang X, Zhang X, Li X, Amos RA, Shaitelman SF, Hoffman K, Howell RM, Salehpour M, Zhang SX, Sun TL, Smith B, Tereffe W, Perkins GH, Buchholz TA, Strom EA, Woodward WA. Accelerated Partial-Breast Irradiation Using Intensity-Modulated Proton Radiotherapy: Do Uncertainties Outweigh Potential Benefits. The British Journal of Radiology 86(20130176), 2013. e-Pub 2013.
- Cao W, Lim G, Li X, Li Y, Zhu X, Zhang X. Incorporating deliverable monitor unit constraints into spot intensity optimization in IMPT treatment planning. Physics in Medicine and Biology 58(15):5113, 2013. e-Pub 2013.
- Li X, Quan EM, Li Y, Pan X, Zhou Y, Wang X, Du W, Kudchadker RJ, Johnson JL, Kuban DA, Lee AK, Zhang X. A fully automated method for CT-on-rails-guided online adaptive planning for prostate cancer intensity modulated radiation therapy. Int J Radiat Oncol Biol Phys 86(5):835-41, 2013. e-Pub 2013. PMID: 23726001.
- Quan EM, Liu W, Wu R, Li Y, Frank SJ, Zhang X, Zhu XR, Mohan R. Preliminary evaluation of multi-field and single-field optimization for the treatment planning of spot-scanning proton therapy of head and neck cancer. Med Phys 40(8):1709, 2013. e-Pub 2013. PMID: 23927306.
- Zhu XR, Poenisch F, Lii M, Sawakuchi G, Titt U, Bues M, Song X, Zhang X, Li Y, Ciangaru G, Li H, Taylor MB, Suzuki K, Mohan R, Gillin MT, Sahoo N. Commissioning dose computation models for spot scanning. Medical Physics 40:041723, 2013. e-Pub 2013.
- Li H, Sahoo N, Poenisch F, Suzuki K, Li Y, Li X, Zhang X, Lee AK, Gillin MT, Zhu XR. Use of treatment log files in spot scanning proton therapy as part of patient-specific quality assurance. Med Phys 40(2):021703, 2013. e-Pub 2013. PMID: 23387726.
- Li H, Li Y, Zhang X, Li X, Liu W, Gillin MT, Zhu XR. Dynamically accumulated dose and 4D accumulated dose for moving tumors. Medical Physics 39(12):7359, 2012. e-Pub 2012.
- Quan EM, Chang JY, Liao Z, Xia T, Yuan Z, Liu H, Li X, Wages C, Mohan R, Zhang X. Automated VMAT treatment planning for stage III lung cancer: how does it compare with IMRT?. Int. J. Radiat. Oncol., Biol., Phys 84(1):e69-e76, 2012. e-Pub 2012.
- Cao W, Lim G, Lee A, Li Y, Liu W, Ron Z, Zhang X. Uncertainty incorporated beam angle optimization for IMPT treatment planning. Medical Physics 39(8):5248, 2012. e-Pub 2012.
- Quan EM, Li X, Wang X, Kudchadker, R, Johnson J, Lee A, Kuban D, Zhang X. A comprehensive comparison of IMRT and VMAT plan quality for prostate cancer treatment. Int. J. Radiat. Oncol., Biol., Phys 83(4):1169-1178, 2012. e-Pub 2012.
- Liu W, Li Y, Cao W, Li X, Zhang X. Influence of robust optimization in intensity-modulated proton therapy with different dose delivery techniques. Medical Physics 39(6):3089, 2012. e-Pub 2012.
- Li Y, Zhu RX, Sahoo N, Anand A, Zhang X. Beyond Gaussians: a study of single spot modeling for scanning proton dose calculation. Phys Med Biol 57(4):983-997, 2012. e-Pub 2012. PMID: 22297324.
- Demkov AA, Seo H, Zhang X, Ramdani J. Using Zintl-Klemm intermetalics in oxide-semiconductor heteroepitaxy. Applied Physics Letter 100:07162, 2012. e-Pub 2012.
- Liu W, Zhang X, Li Y, Mohan R. Robust Optimization of Intensity Modulated Proton Therapy. Med Phys 39(2):1079, 2012. e-Pub 2012. PMID: 22320818.
- Zhang X, Liu W, Li Y, Li X, Quan M, Mohan R, Anand A, Sahoo N, Gillin M, Zhu XR. Parameterization of multiple Bragg curves for scanning proton beams using simultaneous fitting of multiple curves. Phys Med Biol 56(24):7725, 2011. e-Pub 2011. PMID: 22085829.
- Wang X, Amos RA, Zhang X, Taddei J, Woodward WA, Karen H, Yu TK, Tereffe W, Oh J, Perkins GH, Salehpour M, Zhang S, Sun TL, Gillin MT, Buchholz T, Strom EA. Potential Clinic Improvements of External Beam Accelerated Partial-Breast Irradiation (APBI) Using Multiple Proton Beam Configurations. Int. J. Radio. Oncol. Biol. Phys 80(5):1464-1472, 2011. e-Pub 2011.
- Register SP, Zhang X, Mohan R, Chang JY. Proton Stereotactic Body Radiation Therapy for Clinically Challenging Cases of Centrally and Superiorly Located Stage I Non-Small Cell Lung Cancer. Int J Radiat Oncol Biol Phys 80(4):1015-1022, 2011. e-Pub 2011. PMID: 20615629.
- Zhang X, Li X, Quan EM, Pan X, Li Y. A methodology for automatic intensity-modulated radiation treatment planning for lung cancer. Phys Med Biol 56(13):3873-3893, 2011. e-Pub 2011. PMID: 21654043.
- Cai B, Zhang X, Drabold D. Building Block Modeling Technique: Application to Tenary Chalcogenide Glasses, g-Ge2As4Se4 and g-AsGe0.8Se0.8. Physics Review B 83(0):092202, 2011. e-Pub 2011.
- Li Y, Zhang X, Mohan R. Efficient dose calculation strategy for intensity modulated proton therapy. Physics in Medicine and Biology 56:N71-84, 2011. e-Pub 2011.
- Li X, Wang X, Li Y, Zhang X. A 4D IMRT planning method using deformable image registration to improve normal tissue sparing with contemporary delivery techniques. Radiat Oncol 6(83):83, 2011. e-Pub 2011. PMID: 21771333.
- Zhu XR, Sahoo N, Zhang X, Robertson D, Li H, Choi S, Lee AK, Gillin MT. Intensity modulated proton therapy treatment planning using single-field optimization: The impact of monitor unit constraints on plan quality. Medical Physics 37(3):1210-1219, 2010. e-Pub 2010.
- Zhang, X, Li Y, Pan X, Li X, Mohan R, Komaki R, Cox JD, Chang JY. Reduced normal tissue dose and individualized radical radiotherapy by IMPT compared with IMRT in NSCLC. Int. J. Radiat. Oncol., Biol., Phys 77(2):357-366, 2010. e-Pub 2010.
- Torres M, Chang E, Mahajan A, Lege D, Riley B, Zhang X, Lii M, Kornguth D, Pelloski C, Woo S. Optimal treatment planning for skull base chordoma: Photons, Protons, or a combination of both. Int. J. Radiat. Oncol., Biol., Phys 74(4):1033-1039, 2009. e-Pub 2009.
- Pan X, Zhang X, Li Y, Mohan R, Liao Z. Impact of using different four-dimensional computed tomography data sets to design proton treatment plans for distal esophageal cancer. Int J Radiat Oncol Biol Phys 73(2):601-9, 2009. e-Pub 2009. PMID: 19147024.
- Hui Z, Zhang X, Starkschall G, Li Y, Mohan R, Komaki R, Cox JD, Chang JY. Effects of interfractional motion and anatomic changes on proton therapy dose distribution in lung cancer. Int J Radiat Oncol Biol Phys 72(5):1385-95, 2008. e-Pub 2008. PMID: 18486357.
- Demkov AA, Zhang XD. Theory of the Sr-induced reconstruction of the Si (001) surface. JOURNAL OF APPLIED PHYSICS 103(10):103710, 2008. e-Pub 2008.
- Li, Y, Zhang X, Lii M, Sahoo N, Zhu XR, Gillin M, and Mohan R. Incorporating partial shining in proton pencil beam dose calculation algorithm. Phys. Med. Biol 53(3):605-616, 2008. e-Pub 2008. PMID: 18199905.
- Wang X, Krishnan S, Zhang X, Dong L, Briere T, Crane CH, Gillin M, Mohan R, Beddar S. Proton radiotherapy for liver tumors: dosimetric advantages over photon plans. Medical Dosimetry 33(4):259-267, 2008. e-Pub 2008. PMID: 18973852.
- Zhang X, Zhao K, Guerrero T, Mcguire S, Yaremko B, Komaki R, Cox JD, Hui Z, Li Y, Newhauser W, Mohan R, Liao Z. 4D-based treatment planning for intensity-modulated radiation therapy and proton therapy for distal esophagus cancer. Int. J. Radiation Oncology Biol. Phys 72:278-287, 2008. e-Pub 2008.
- Li Y, Zhang X, Dong L, Mohan R. A novel patch field optimization algorithm using optimized grid filter for passively scattered proton beams. Phys. Med. Biol 52:N265-N275, 2007. e-Pub 2007.
- Zhang X, Dong L, Lee AK, Cox JD, Kuban DA, Zhu RX, Wang X, Li Y, Newhauser WD, Gillin M, Mohan R. Effect of anatomic motion on proton therapy dose distribution in prostate cancer treatment. Int J Radiat Oncol Biol Phys 67:620-629, 2007. e-Pub 2007. PMID: 17236979.
- Kang Y, Zhang X, Chang JY, Wang H, Wei X, Liao Z, Komaki R, Cox JD, Balter PA, Liu H, Zhu XR, Mohan R, Dong L. 4D Proton treatment planning strategy for mobile lung tumors. Int J Radiat Oncol Biol Phys 67:906-914, 2007. e-Pub 2007. PMID: 17293240.
- Chang J, Zhang X, Cox JD. Conformity index (CI) and radiation treatment of lung cancer. Int J Radiation Oncology Biol Phys 68:1272, 2007. e-Pub 2007.
- Newhauser W, Fontenot J, Zheng Y, Polf J, Titt U, Koch N, Zhang X, Mohan R. Monte Carlo simulations for configuring and testing an analytical proton dose-calculation algorithm. Phys. Med. Biol 52:4569-4584, 2007. e-Pub 2007.
- Chang JY, Zhang X, Wang X, Kang Y, Riley B, Bilton S, Mohan R, Komaki R, Cox JD. Significant reduction of normal tissue dose by proton radiotherapy compared with three-dimensional conformal or intensity-modulated radiation therapy in Stage I or Stage III non-small-cell lung cancer. Int J Radiat Oncol Biol Phys 65(4):1087-96, 2006. e-Pub 2006. PMID: 16682145.
- Liu HH, Jauregui M, Zhang X, Wang X, Dong L, Mohan R. Beam angle optimization and reduction for intensity-modulated radiation therapy of non-small-cell lung cancers. Int. J. Radiat. Oncol. Biol. Phys 65(2):561-572, 2006. e-Pub 2006. PMID: 16690438.
- Zhang X, Wang X, Dong L, Liu H, Mohan R. A sensitivity-guided algorithm for automated determination of IMRT objective function parameters. Med. Phys 33:2935-2944, 2006. e-Pub 2006. PMID: 16964872.
- Mohan R, Zhang X, Wang H, Kang Y, Wang XC, Liu H, Dong L. Use of deformed intensity distributions for on-line modification of image-guided IMRT to account for interfractional anatomic changes. Int J Radiat. Oncol. Biol. Phys 61:1258-1266, 2005. e-Pub 2005. PMID: 15752908.
- Wang X, Zhang X, Dong L, Liu H, Gillin M, Anand A, Ang K, Mohan R. Effective of non-coplanar IMRT planning using a parallelized multiresolution beam angle optimization method for paranasal sinus carcinoma. Int J Radiat. Oncol. Biol. Phys 63:549-601, 2005. e-Pub 2005.
- Wang X, Zhang X, Dong L, Liu H, Wu Q, Mohan R. Development of beam angle optimization for IMRT using accelerated exhaustive search strategy. Int J Radiat Oncol Biol Phys 60:1325-1137, 2004. e-Pub 2004. PMID: 15519806.
- Zhang X, Liu H, Wang X, Dong L, Wu Q, Mohan R. Speed and convergence properties of gradient algorithms for optimization of IMRT. Med. Phys 31:1141-1152, 2004. e-Pub 2004. PMID: 15191303.
- Fonseca L, Korkin A, Demkov AA, Zhang X, Knizhnik A. Atomistic calculation of leakage current through ultra-thin metal-oxide barriers. Microelectronic engineering 69:130-137, 2003. e-Pub 2003.
- Zhang X, Demkov AA. Theory of the atomic and electronic structure of the Si/SrTiO3 interface. Phys. Rev. B 68:125323, 2003. e-Pub 2003.
- Droopad R, Yu Z, Li H, Liang Y, Overgaard C, Demkov AA, Zhang X, Moore K, Eisenbeiser K, Hu M, Curless J, Finder J. Development of integrated hetero structures on silicon by MBE. J. Crystal Growth 251:638, 2003. e-Pub 2003.
- Hu XM, Li H, Liang Y, Wei Y, Yu Z, Marshall D, Edwards J, Droopad R, Zhang X, Demkov AA, Moore K, Kulik J. The interface of epitaxial SrTiO3 on silicon: in situ and ex situ studies. Appl. Phys. Lett 82:203, 2003. e-Pub 2003.
- Tisinger LH, Liu R, Kulik J, Zhang X, Ramdani J, Demkov AA. Ultraviolet-Raman studies of SrTiO3 ultrathin films on Si. Journal of Vacuum Science & Technology B 21(1):53-56, 2003. e-Pub 2003.
- Li H, Hu X, Wei Y, Yu Z, Zhang X, Droopad R, Demkov AA, Edwards J, Moore K, Ooms W, Kulik J, Fejes PJ. Two-dimensional growth of high-quality strontium titanate thin films on Si. J. Appl. Phys 93:4521, 2003. e-Pub 2003.
- Zhang X, Fonseca L, Demkov AA. The application of density functional, local orbitals, and scattering theory to quantum transport. Phys. Stat. Sol. B 233:70, 2002. e-Pub 2002.
- Taraskin SN, Fry PA, Zhang X, Drabold DA, Elliott SR. Spatial decay of the single-particle density matrix in tight-binding metals: Analytic results in two dimensions. Phys. Rev. B 66:233101, 2002. e-Pub 2002.
- Zhang X, Demkov A. Steps on the (001) SrTiO3 surface. J. of Vac, Sci. Tech. B 20:1664, 2002. e-Pub 2002.
- Zhang X, Fonseca L, Demkov AA. First principles study of electron transport through atomistic metal-oxide-semiconductor structures. In proceedings of the 2002 International Conference on Computational Nanoscience, ICCN 2002, M. Laudon and B.Romanowicz, Eds. Computational Publications):322, 2002. e-Pub 2002.
- Zhang X, Drabold D. Understanding light induced electron spin resonance by ab-inito molecular dynamic simulation. Int. J. Mod. Phys. B 24-25:3190, 2001. e-Pub 2001.
- Demkov AA, Zhang X, Loechelt H. Theoretical investigation of ultrathin gate dielectrics. VLSI Design 13:1-4, 2001. e-Pub 2001.
- Demkov AA, Zhang X, Drabold D. Towards a First principle simulation and current-voltage characteristic of atomistic metal-oxide-semiconductor structures. Phys. Rev. B 64:125306, 2001. e-Pub 2001.
- Zhang X, Drabold D. Properties of the density matrix from realistic calculations. Phys. Rev. B 63:233109, 2001. e-Pub 2001.
- Demkov AA, Liu R, Zhang X. Theoretical investigation of gate dielectrics. Proceedings of the 27th International symposium on Compound Semiconductors (IEEE) 27:155, 2000. e-Pub 2000.
- Zhang X, Drabold D. Structural and electronic properties of amorphous GeSe2 surfaces. Phys. Rev. B 62(23):15695-15701, 2000. e-Pub 2000.
- Wang Z, Wang XB, Wang XC, Zhang X. Spectra of halo nuclei. Communications in Theoretical Physics 33(1):81-86, 2000. e-Pub 2000.
- Demkov AA, Liu R, Zhang X, Loechelt H. Theoretical and experimental investigation of ultra-thin oxynitrides and the role of nitrogen at the Si-SiO2 interface. J. of Vac. Suf. Tech B18:2388, 2000. e-Pub 2000.
- Zhang X, Drabold D. ab-initio simulation of photo-structural change in amorphous selenium. Physical Review Letters 83(24):5042-5045, 1999. e-Pub 1999.
- Zhang X, Drabold D. Evidence for valence alternation and new model for amorphous Selenium. J. Non Crysal Solids 241:195, 1998. e-Pub 1998.
- Wang Z, Zhang X, Wang XC, Wang XB. Self-similar structure shell model. High Energy Physics and Nuclear Physics 22(4):333-340, 1998. e-Pub 1998.
- Ge L, Zhang X. Study of Reaction Induced by Radioactive Beams. Nuclear Physics Review 14:19-26, 1997. e-Pub 1997.
- Chen L, Ge L, Zhang X, Zhang F. Isospin equilibrium and non-equilibrium in Heavy Ion Collision at intermediate energies. J. Phys. G 23:211-218, 1997. e-Pub 1997.
- Wang Z, Zhang X, Wang XC, Wang XB. Structure of Light Nuclei on Neutron Drip line. Communications in Theoretical Physics 49:49-56, 1997. e-Pub 1997.
- Zhang X, Ge L. Study of -(11)Li-Induced Reactions via QMD Model. High Energy Physics and Nuclear Physics 20:270-276, 1996. e-Pub 1996.
- Chen L, Zhang X, Ge L. Isospin Effect on pre-equilibrium nucleon emission in Heavy Ion Collision. High Energy Physics and Nuclear Physics (in Chinese) 20:1091-1096, 1996. e-Pub 1996.
- Wang Z, Zhang X, Wang XC, Wang XB. Ground State Properties of Halo Nuclei. Z. Phys A 356:255, 1996. e-Pub 1996.
- Wang Z, Zhang X, Wang XC, Wang XB. Physical Mechanism of Neutron Halo on Drip Line Light Nuclei. Chin. Phys. Lett 12:705, 1995. e-Pub 1995.
- Wang Z, Zhang X, Wang XC, Wang XB. Structure of Halo Nuclei. Chin. J. of Nucl. Phys 17:137, 1995. e-Pub 1995.
- Zhang X, Ge L. Fluctuations and Emission of Intermediate Mass Fragments in HIC. High Energy Physics and Nuclear Physics (in Chinese) 19(10):945-951, 1995. e-Pub 1995.
- Ge L, Zhang X, Zhu Q. Intermittence in Heavy Collision at Intermediate and High Energies. High Energy Physics and Nuclear Physics (in Chinese) 18:428-432, 1994. e-Pub 1994.
- Zhang X, Ge L, Zhu Q. Intermittence in Heavy ion Collision at Intermediate and High Energies. Chinese J. of Nuclear Physics 16:308, 1994. e-Pub 1994.
- Zhu Q, Ge L, Zhang X. Isospin Effect in Heavy Ion Collision. High Energy Physics and Nuclear Physics (in Chinese) 18:853-857, 1994. e-Pub 1994.
Invited Articles
- Wang X, Woodward W, Zhang X, Taddei P. Proton Therapy for breast cancer, invited. Transactions of the American Nuclear Society 101:1085-1088, 2009. e-Pub 2009.
Review Articles
- Knäusl, B, Belotti, G, Bertholet, J, Daartz, J, Flampouri, S, Hoogeman, M, Knopf, A, Lin, H, Moerman, A, Paganelli, C, Ruciński, A, Schulte, R, Shimizu, S, Stützer, K, Zhang, X, Zhang, Y, Czerska, K. A review of the clinical introduction of 4D particle therapy research concepts. Physics and Imaging in Radiation Oncology 29, 2024. e-Pub 2024. PMID: 38298885.
- Zhu XR, Li Y, Mackin D, Li H, Poenisch F, Lee AK, Mahajan A, Frank SJ, Gillin MT, Sahoo N, Zhang X. Towards effective and efficient patient-specific quality assurance for spot scanning proton therapy. Cancers (Basel) 7(2):631-47, 2015. e-Pub 2015. PMID: 25867000.
Professional Educational Materials
- Zhang X, Demkov D. Theoretical study of Sr induced reconstruction of Si(001) surface (Motorola-ORNL CRADA report), 2002.
- Cai L, Juedes D, Zhang X. A local improvement schema for approximation algorithms with applications to multiple sequence alignment, used as the teaching manual for Prof. Cais Algorithm class, 2000.
Editorials
- Demkov AA, Zhang X, Allmen P. Preface:. Phys. Stat. Sol. B 233:3, 2002.
Abstracts
- Sahoo N, Zhu X, Zhang X, Poenisch F, Li H, Wu R, Lii M, Umfleet W, Gillin M, Mahajan A, Grosshans D. Analysis of the Impact of Range and Setup Uncertainties On the Dose to Brain Stem and Whole Brain in the Passively Scattered Proton Therapy Plans (SU-E-T-493) 41(6):340, 2014. e-Pub 2014.
- Jiang S, Liao L, Li Y, Wang X, Li H, Zhu X, Sahoo N, Gillin M, Hojo Y, Sun J, Chang J, Liao Z, Grosshans D, Frank S, Zhang X. A Novel Hybrid Planning Approach to Allow More Patients Benefited by the Intensity Modulated Proton Therapy (SU-E-P-06) 41(6):128, 2014. e-Pub 2014.
- Liao L, Jiang S, Li Y, Wang X, Li H, Zhu X, Sahoo N, Gillin M, Mahajan A, Grosshans D, Lim G, Zhang X. TH-C-BRD-12 Robust Intensity Modulated Proton Therapy Plan Can Eliminate Junction Shifts for Craniospinal Irradiation 41(6):84, 2014. e-Pub 2014.
- Li H, Li X, Zhu X. TH-C-BRD-07 Minimizing Dose Uncertainty for Spot Scanning Beam Proton Therapy of Moving Tumor with Optimization of Delivery Sequence 41(6):84, 2014. e-Pub 2014.
- Mackin D, Zhang X, Li Y, Li H, Wu R, Poenisch F, Suzuki K, Kerr M, Holmes C, Zhu X, Sahoo N, Gillin M. MO-F-16A-05 Spot-Scanning Proton Therapy Patient-Specific Quality Assurance: Our Methodology and Results From 295 Treatment Plans 41(6):61, 2014. e-Pub 2014.
- Du W, Cho S, Zhang X, Hoffman K, Kudchadker R. Decoding the Beam Complexity in Intensity-Modulated Radiation Therapy Plans (SU-E-T-353) 41(6):305, 2014. e-Pub 2014.
- Stoker J, Amos R, Li Y, Liu W, Park P, Sahoo N, Zhang X, Zhu X, Gillin AM. SU‐E‐T‐693: Comparison of Discrete Spot Scanning and Passive Scattering Craniospinal Proton Irradiation. Medical Physics 40(6):365, 2013. e-Pub 2013.
- Li H, Park P, Liu W, Matney J, Liao Z, Zhang X, Zhu AX. SU‐E‐T‐365: Respiratory Motion‐Induced Dose Uncertainty in Step‐And‐Shoot IMRT. Medical Physics 40(6):288, 2013. e-Pub 2013.
- Sahoo N, Dhanesar S, Poenisch F, Lii M, Li H, Zhang X, Amos R, Wu R, Gillin M, Zhu AX. SU‐E‐T‐04: Application of a Semi‐Empirical Formula to Determine Spread Out Bragg Peak Factors and Range Shifter Factors From Measured Depth Dose Curves for Passively Scattered Proton Beams. Medical Physics 40(6):203, 2013. e-Pub 2013.
- Cao W, Lim G, Li X, Li Y, Zhang AX. TU‐A‐108‐04: An Investigation of Optimizing Proton Energies in IMPT Treatment Planning. Medical Physics 40(6):420, 2013. e-Pub 2013.
- Liao L, Cai B, Li Y, Cao W, Lim G, Li H, Zhang AX. MO‐G‐137‐04: Using Molecular Dynamics Simulation Algorithm to Overcome the Local Minima of Gradient Methods in IMPT Treatment Plan Optimization. Medical Physics 40(6):413, 2013. e-Pub 2013.
- Taylor M, Liao Z, Bluett J, Kerr M, Li H, Sahoo N, Gillin M, Zhu X, Zhang AX. MO‐G‐137‐05: Improving Passive Scattering Proton Therapy Plan Quality by Optimizing Compensator Parameters. Medical Physics 40(6):416, 2013. e-Pub 2013.
- Wang X, Liao L, Wang H, Li H, Li Y, Li X, Quan M, Liao Z, Zhang AX. SU‐E‐T‐471: Potential of Using Simultaneous Integrated Boost (SIB) to Significantly Improve the Normal Tissue Sparing For Advanced Staged Non‐Small Cell Lung Cancer(NSCLC). Medical Physics 40(6):314, 2013. e-Pub 2013.
- Mackin D, Zhang X, Li Y, Taylor M, Kerr M, Holmes C, Sahoo N, Poenisch F, Li H, Lii M, Amos R, Wu R, Suzuki K, Gillin M, Zhu AX. SU‐E‐T‐157: Improving Spot Scanning Proton Therapy Patient‐Specific Quality Assurance Through Early Application of Second‐Check Dose Calculation Software. Medical Physics 40(6):240, 2013. e-Pub 2013.
- Zhang X, Li Y, Kardar L, Li H, Li X, Wang X, Cao W, Lim G, Liao Z, Cox J, Chang J, Sahoo N, Gillin M, Zhu XR. Evaluation and mitigate the interplay effects for IMPT treatment of lung cancers in a clinical setting. PTCOG 52, 2013. e-Pub 2013.
- Liu W, et al. Comparison of PTV plus PRV-Based Optimization and Robust Optimization in Intensity-Modulated Proton Therapy. Medical Physics 39(6):3849-3850, 2012. e-Pub 2012.
- Cao W, et al. An Investigation of the Impact of Spot Scanning on Plan Quality Using IMPT Optimization Incorporating Deliverable Monitor Unit Constraints. Medical Physics 39(6):3891-3891, 2012. e-Pub 2012.
- Liu W, et al. Effectiveness of Robust Optimization in Head and Neck IPT Dose Distributions. Medical Physics 39(6):3835-3835, 2012. e-Pub 2012.
- Quan E, et al. Improvement in Robustness and Delivery Efficiency of Intensity-Modulated Proton Therapy Using Single-Field Optimization with Energy Absorber. Medical Physis 39(6):3965-3965, 2012. e-Pub 2012.
- Quan E, Chang J, Liao Z, Xia T, Liu H, Li X, Balter P, Zhang X. Automated VMAT Treatment Planning for Stage III Lung Cancer: How Does It Compare with IMRT?”. Medical Physics 38(6):3671, 2011. e-Pub 2011.
- Wang X, Zhang X, Amos R, Salehpour, Zhang S, Sun T, Strom E, Buchholz T, Hoffman K, Woodward W. External Beam Accelerated Partial Breast Irradiation Using Intensity Modulated Proton Therapy (IMPT). Medical Physics 38(6):3669, 2011. e-Pub 2011.
- Cao W, Lim G, Li Y, Zhang X. Angle Optimization to Improve Treatment Plan Quality of Intensity Modulated Proton Therapy (IMPT) for Prostate Cancer. Medical Physics 38(6):3741, 2011. e-Pub 2011.
- Li X, Chang J, Liu W, Quan E, Balter P, Zhang X. Significant Improvement of Plan Quality, Delivery Efficiency and Plan Consistency by VMAT Combined with Automated Inverse Planning Algorithm for Stereotactic Body Radiation Therapy in Centrally/superiorly Located Stage I Non‐Small‐Cell Lung Cancer. Medical Physics 38(6):3866, 2011. e-Pub 2011.
- Liu W, Zhang X, Li Y, Mohan R. Benefits from Achilles' heel of intensity-modulated proton therapy via worst-case robust optimization. Medical Physics 38(6):3685, 2011. e-Pub 2011.
- Li Y, Liu W, Li X, Quan E, Zhang X. Toward a Thorough Evaluation of IMPT plan sensitivity to Uncertainties: Revisit the Worst-Case Analysis with an Exhaustively Sampling Approach. Medical Physics 38(6):3853, 2011. e-Pub 2011.
- Li Y, Zhang X, Mohan R. A Hybrid Inverse Planning Algorithm of IMPT Optimization. Medical Physics 35(6):2867, 2011. e-Pub 2011.
- Zhu X, Titt U, Bues M, Sahoo N, Ciangaru G, Sawakuchi G, Poenisch F, Lii M, Zhang X, Li Y, Arjomandy B, Suzuki K, Mohan R, Gillin M. Configuration and Validation of a Single Gaussian Dose Model for Scanning Proton Beams. Medical Physics 36(6):2666, 2011. e-Pub 2011.
- Li X, Quan E, Wang X, Li Y, Pan X, Zhang X. A Novel Fully Automated Re-Planning Method for CT-Guided Adaptive Planning in IMRT and SmartArc for Prostate Cancer. Medical Physics 37(6):3191, 2010. e-Pub 2010.
- Quan EM, Li X, Li Y, Wang X, Zhang X. How could fixed beam intensity modulated radiotherapy exceed SmartArc?. Medical Physics 37(6):3437, 2010. e-Pub 2010.
- Tsunashima Y, Vedam S, Dong L, Zhang X, Umezawa, Balter P, Mohan R. What is the Maximum Number of Beam Spot Deliverable Within One Gating Window for Synchrotron Based Scanning Proton Beam Therapy?. Medical Physics 37(6):3364, 2010. e-Pub 2010.
- Zhu X, Sahoo N, Zhang X, Robertson, Li H, Choi S, Lee A, Gillin M. The Impact of Monitor Unit Constraints on Plan Quality of IMRT Planning using Single Field Optimization. Medical Physics 37(06):3365, 2010. e-Pub 2010.
- Pan X, Zhang X, Li Y, Li X, Chang J, Zhu X, Mohan R. Inverse beam angle optimization in IMRT for lung cancer patients. Medical Physics 37(6):3341, 2010. e-Pub 2010.
- Li Y, Li X, Luo D, Quan E, Pan T, Sahoo N, Chang J, Mohan R, Zhang X. A Novel Inverse Planning Strategy for Dose Escalation with PET Image Guidance in RT of NSCLC. Medical Physics 37(06):3211, 2010. e-Pub 2010.
- Cao W, et al. IMRT vs. Passively Scattered Proton Therapy (PSPT) for Locally Advanced Non-small Cell Lung CA (LA NSCLC) Randomized Trial - Is there Equipoise?. Int'l Journal of Radiation Oncology Biology Physics 78(3):S201-S202, 2010. e-Pub 2010.
- Zhang X, et al. Improving Clinical Potential, Efficiency and Robustness of Planning and Delivery of IMPR for Skull-based Chordomas. Int'l Journal of Radiation Oncology Biology and Physics 78(3):S804-S804, 2010. e-Pub 2010.
- Zhang, Zhu X, Dong R, Li L, Trofimov Y, Delaney A, Mahajan T, Mohan A, R. Improving Clinical Potential, Efficiency and Robustness of Planning and Delivery of IMPT for Skull-based Chordomas. International Journal of Radiation Oncology Biology Physics 78(3):S804-S804, 2010. e-Pub 2010.
- Trofimov, Kang A, Unkelbach J, Adams J, Zhang J, Bortfeld X, Liebsch T, DeLaney N, T F. Evaluation of Dosimetric Gain and Uncertainties in Proton Therapy Delivery with Scanned Pencil Beam in Treatment of Base-of-skull and Spinal Tumors. International Journal of Radiation Oncology Biology Physics 78(3):S133-S134, 2010. e-Pub 2010.
- Mohan, Zhang R, Matney X, Bluett J, Dong J, Balter L, Engelsman P, Choi M, Komaki N, Liao R, Z. IMRT vs. Passively Scattered Proton Therapy (PSPT) for Locally Advanced Non-small Cell Lung CA (LA NSCLC) Randomized Trial - Is there Equipoise?. International Journal of Radiation Oncology Biology Physics 78(3):S201-S202, 2010. e-Pub 2010.
- Tsunashima Y, Vedam S, Dong L, Zhang X, Umezawa U, Smith A, Balter P, and Mohan R. Efficiency of Respiratory-Gated Synchrotron Based Scanning Beam Delivery of Proton Therapy for Lung. Medical Physics 36(6):2550, 2009. e-Pub 2009.
- Pan X, Li X, Li Y, Mohan R, Zhang X. Dose Painting by Numbers Using Single Photon Emission Computed Tomography with Intensity-Modulated Radiotherapy to Reduce Dose to Highly Functional Lung Region for Lung Cancer Patients. Medical Physics 36(6):2642, 2009. e-Pub 2009.
- Li Y, Zhang X, Li X, Pan X, Mohan R. Evaluating 4D Interplay Effects for Proton Scanning Beams in Lung Cancers. Medical Physics 36(6):2009, 2009. e-Pub 2009.
- Li X, Wang X, Li Y, Pan X, Mohan R, Zhang X. 4D IMRT Planning Method Using Deformable Image Registration for Lung Cancer. Medical Physics 36(6):2701, 2009. e-Pub 2009.
- Robertson D, Zhang X, Li Y, Lee A, Gillin M, Zhu X, Mohan R. Optimizing Spot Spacing and Margin for Intensity-Modulated Proton Therapy Planning. Medical Physics 36(6):2554, 2009. e-Pub 2009.
- Zhang X, Sahoo N, Sawakuchi, Lii M, Ciangaru G, Bues M, Pan X, Zhang X, Ding X, Titt U, Arjomandy B, Suzuki K, Mohan R, Gillin M. Configuration and Validation of a Double Gaussian Dose Model for Scanning Proton Beams. Medical Physics 36(6):2667, 2009. e-Pub 2009.
- Mirkovic D, Titt U, Sawakuchi G, Zhang X, Li Y, Mohan R. Monte Carlo Computation of the Effective Dose in Scanning Beam Proton Therapy. Medical Physics 36(6):2612, 2009. e-Pub 2009.
- Pan X, Zhang X, Li Y, Li X, Wang X, Mohan R. Automated Planning for Fast On‐Line CT‐Guided Adaptive Re‐Planning in IMRT for Prostate Cancer Patients. Medical Physics 36(6):2538, 2009. e-Pub 2009.
- Pan X, Zhang X, Li Y, Mohan R. The Study of Clinical Application of GEUD‐Based Optimization in IMRT Treatment Planning for Lung Cancer Patie. Medical Physics 35(6):2754, 2008. e-Pub 2008.
- Kang Y, Dong L, Vicic M, Zhang L, Zhang X, Mohan R. On-Line CT-Guided Adaptive Re-Planning Based On Deformed Original Dose Distributions. Medical Physics 35(6):2640, 2008. e-Pub 2008.
- Titt U, Zhang X, Li Y, Mirkovic, Sawakuchi G, Mohan R. Monte Carlo Study of Distal Edge Degradation in Proton Therapy Due to Heterogeneities. Proof of Principle with a Case Study. Medical Physics 35(6):2798, 2008. e-Pub 2008.
- Li Y, Li X, Pan X, Dong L, Mohan R, Zhang X. An N‐State 4D Convolution Dose Calculation Algorithm in Proton and Photon Therapy. Medical Physics 35(6):2751, 2008. e-Pub 2008.
- Zhang X, et al. Reduced normal tissue dose and individualized radical therapy by intensity modulated proton therapy compared with intensity modulated photon therapy in NSCLC. Int'l Journal of Radiation Oncology Biology Physics 72(1):S447-S447, 2008. e-Pub 2008.
- Newhauser W, et al. Monte arlo simulations for configuring and testing an analytical proton dose-calculation algorithm. Physics in Medicine and Biology 52(15):4569-4584, 2007. e-Pub 2007.
- Newhauser W. A Monto-Carlo based dose engine for proton radiotherapy treatment planning. Medical Physics 34(6):2406-2406, 2007. e-Pub 2007.
- Mohan R. Reducing uncertainties in proton therapy - Achieving "What you see is what you get". Medical PHysics 34(6):2552-2552, 2007. e-Pub 2007.
- Li Y, et al. Proton dose calculation incorporating respiratory motion. Medical Physics 34(6):2485-2485, 2007. e-Pub 2007.
- Pan X, Zhang X, Li Y, Mohan R. A robust proton treatment planning strategy to account the diaphragm motion for the esophagus cancer using 4D CT. Med. Phys 34(6):2409-2410, 2007. e-Pub 2007.
- Mohan R, Zhang X, Titt U, Zhu X, Dong L. Achieving what you see is what you get. Med. Phys 34(6):2552, 2007. e-Pub 2007.
- Li Y, Zhang X, Zhang M, Dong L, Mohan R. Proton dose calculation incorporating respiratory motion. Med. Phys 34(6):2485, 2007. e-Pub 2007.
- Li Y, Zhang X, Mohan R. Modeling partial shining in proton therapy. Med. Phys 34(6):2469, 2007. e-Pub 2007.
- Pan X, et al. A robust proton treatment planning strategy to account the diaphragm motion for the esophagus cancer using 4D CT 34(6):2409-2410, 2007. e-Pub 2007.
- Wu R, Zhang X, Amos R, Prado K, Lii M, Sahoo N, Gillin M, Zhu X. Evaluation of titanium metal imaging artifacts on proton dose calculation. Med. Phys 34(6):2452, 2007. e-Pub 2007.
- Newhauser WD, Fontenot J, Zheng Y, Taddei P, Mirkovic D, Titt U, Zhu X, Sahoo N, Schaffner B, Langenegger A, Koch N, Zhang X, Mohan R. A Monte-Carlo based dose engine for proton radiotherapy treatment planning. Med. Phys 34(6):2406, 2007. e-Pub 2007.
- Hui Z, et al. Effegts of inter-fraction anatoic changes on proton therapy dose distributions in lung cancer. Int'l Journal of Radiation Oncology Biology Physics 69(3):S190-S190, 2007. e-Pub 2007.
- Arjomandy B, Balter P, Zhang X, Chang J. Proton lung sterotactic body radiotherapy treatment method. Med. Phys 33(6):2297, 2006. e-Pub 2006.
- Newhauser WD, Zheng Y, Fontenot J, Koch N, Polf J, Schaffner B, Titt U, Zhang X, Zhu X, Mohan R. Implementation of the varian eclipse system for proton therapy treatment planning. Med. Phys 33(6):2284, 2006. e-Pub 2006.
- Zhang X, Chang J, Liao Z, Komaki R, Cox J, Amos R, Arjomandy B, Kang Y, Wang X, Liu H, Dong L, Mohan R. Thoracic proton treatment planning strategies based on the 4D CT information. Med. Phys 33(6):2269, 2006. e-Pub 2006.
- Li Y, Zhang X, Dong L, Mohan R. A novel patch field design using optimized grid filter for passively scattered proton beams. Med. Phys 33(6):2207, 2006. e-Pub 2006.
- Zhang X, et al. Thoracic proton treatment planning strategies based on the 4D-CT information. Medical Physics 33(6):2269-2269, 2006. e-Pub 2006.
- Newhauser W, et al. Implementation of the Varian eclipse system for proton therapy treatment planning 33(6):2284-2284, 2006. e-Pub 2006.
- Li Y, et al. A novel patch field design using optimized grid filter for passively scattered proton beams. Medical Physics 33(6):2207-2207, 2006. e-Pub 2006.
- Mohan R, Dong L, Zhang X. Recent advances in image-guided radiotherapy. Radiotherapy and Oncology 78:S27-S28, 2006. e-Pub 2006.
- Mohan R, Dong L, Zhang XD. Recent advances in image-guided radiotherapy. Radiotherapy and Oncology 78:S27-S28, 2006. e-Pub 2006.
- Kang Y, Zhang X, Wang H, Chang J, Liao R, Komaki R, cox J, Mohan R, Rosen I, Prado K, Balter P, Liu H, Dong L. Proton Treatment Planning for Mobile Lung Tumors. Med. Phys 32(6):2144, 2005. e-Pub 2005.
- Zhang X, Dong L, Zhu X, Zein R, Lim J, Wang X, Mohan R, Gillin M, Dong L. Software tools for transferring treatment plans between two planning systems, 2005. e-Pub 2005.
- Zhang X, Dong L, Lee A, Cox J, Zhu X, Wang X, Kang Y, Liu H, Mohan R. Impact of inter-fractional motion on the anatomy on prostate proton dose. Med. Phys 32(6):2029-2030, 2005. e-Pub 2005.
- Kang Y, et al. Proton treatment planning for mobile lung tumors. Medical Physics 32(6):2114-2114, 2005. e-Pub 2005.
- Zhang X, et al. Impact of inter-fractionalmotionof the anatomy on prostate proton dose. Medical Physics 32(6):2029-2030, 2005. e-Pub 2005.
- Chang J, et al. Significantly reduced normal tissue dose with proton radiotherapy compared with 3D-CT or IMRT in stage I or stage III non-small-cell lunc cancer. Int'l Journal of Radiation Oncology Biology Physics 63(2):S403-S403, 2005. e-Pub 2005.
- Wang X, Krishnan S, Zhang X, Beddar S, Wang H, Mohan R, Gillin M, Dong L. Treatment planning study using protons for liver patients. Int J Radiat. Oncol. Biol. Phys 63(2):S205-S206, 2005. e-Pub 2005.
- Chang JY, Zhang X, Wang X, Kang Y, Liao Z, Komaki R, Cox JD, Mohan R. Significantly reduced normal tissue dose with proton radiotherapy compared with 3D-CRT or IMRT in stage I or stage III non-small cell lung cancer. Int J Radiat Oncol Biol Phys 63(2):S403, 2005. e-Pub 2005.
- Wang X, et al. Treatment planning study using protons for liver patients. Int'l Journal of Radiation Oncology Biology Physics 63(2):S205-206, 2005. e-Pub 2005.
- Wang X, et al. Non-coplanar Beam angle optimization for Paranasal sinus IMRT using parallezised 'Multi-resolution" method. Medical Physics 31(6):1778-1778, 2004. e-Pub 2004.
- Zhang X, Wang X, Liu H, Dong L, Mohan R. A Sensitivity guided algorithm to automated determination of objective function parameters for IMRT. Med. Phys 31Su-DD-PDS:11682, 2004. e-Pub 2004.
- Zhang X, et al. A sensitivity guided algorithm to automated detterminationof objective function parameters for IMRT. Medical Physics 31(6):1714-1715, 2004. e-Pub 2004.
- Liu H, et al. Beam angle optimization and reduction for IMRT of thoracic cancers. Medical Physics 31(6):1866-1866, 2004. e-Pub 2004.
- Dong L, Liu H, Wang X, Zhang X, Tu S, Gillin M, Mohan R, Wu Q. The Effect of Photon Beam Energy On the Quality of IMRT Plans. Med. Phys 30PO-T-112:1485, 2004. e-Pub 2004.
- Liu H, Wang X, Dong L, Wu Q, Zhang X, Tu S, Mohan R. An Investigation of the Feasibility of Sparing Lung and Other Thoracic Organs Using IMRT for Treating Non-Small-Cell Lung Cancer. Med. Phys 30PO-T-110:1485, 2004. e-Pub 2004.
- Liu H, Jauregui M, Zhang X, Wang X, Dong L, Mohan R. Beam Angle Optimizaiton and Reduction for IMRT of Thoracic Cancers. Med. Phys 31(6):1866, 2004. e-Pub 2004.
- Mohan R, et al. Deforming intensity distributions to incorporate inter-fraction anatomic variations for image-guided IMRT. Int'l Journal of Radiation Oncology Biology Physics 60(1):S22-S227, 2004. e-Pub 2004.
- Mohan R, Zhang X, Wang X, Kang Y, Wang XC, Liu H, Dong L. Use of deformed intensity distributions for on-line modification of image-guided IMRT to account for inter-fractional anatomic changes. Int J Radiat. Oncol. Biol. Phys 60:S226-S227, 2004. e-Pub 2004.
- Liu H, et al. An investigation of the feasibility of sparing lung and other thoracic organs using IMRT for treating non-small-cell lung cancer. Medical Physics 30(6):1485-1485, 2003. e-Pub 2003.
- Wang X, et al. Use of exhaustive search, parallel-computing and dose approximaqtions to develop strategies for IMRT beam configuration optimization. Medical Physics 30(6):1373-1374, 2003. e-Pub 2003.
- Zhang X, et al. Acceleration of IMRT optimization process. Medical Physics 30(6):1385-1385, 2003. e-Pub 2003.
- Wang X, Zhang X, Dong L, Liu H, Tu S, Mohan R, Wu Q. Use of Exhaustive Search, Parallel-Computing and Dose Approximations to Develop Strategies for IMRT Beam Configuration Optimization. Med. Phys 30Mo-E20B-09:1373, 2003. e-Pub 2003.
- Zhang X, Wang X, Dong L, Liu H, Tu S, Mohan R. Acceleration of IMRT Optimization Process. Med. Phys 30Tu-C20B-05:1385, 2003. e-Pub 2003.
- Dong L, et al. The effect of photon beam energy on the quality of IMRT plans. Medical Physics 30(6):1485-1485, 2003. e-Pub 2003.
Book Chapters
- Drabold DA, Zhang X, Li J. First principles molecular dynamics and photostructural response in amorphous silicon and glassy chalcogenides. (cover of the book from this chapter). In: Photo-induced metastability in amorphous semiconductors. Wiley-VCH, 260-276, 2003.
- Drabold DA, Nakhmanson S, Zhang X. Electronic structure of amorphous insulators and photo structural effects in chalcogenide glasses, properties. In: Properties and applications of amorphous materials. Kluwer, 221-250, 2001.
Letters to the Editor
- Chang JY, Zhang X. In Reply to: Impact of contouring variations in evaluating planning approaches for stereotactic body. International Journal of Radiation Oncology Biology Physics.
Patents
- Zhang X, Pan X, Li X, Li Y, Quan E, Mohan R. AUTOMATED TREATMENT PLANNING FOR RADIATION THERAPY. Patent Number: US8986186B2.
Patient Reviews
CV information above last modified March 31, 2026