Yejing Ge
Department of Cancer Biology, Division of Division of Discovery Science
Present Title & Affiliation
Primary Appointment
Assistant Professor, Department of Cancer Biology, Division of Basic Science Research, The University of Texas MD Anderson Cancer Center, Houston, TX
Education & Training
Degree-Granting Education
| 2012 | University of Illinois Urbana Champaign, Urbana-Champaign, IL, USA, PHD, Molecular, Cell and Development Biology |
| 2006 | Tsinghua University, Beijing, CHN, BS, Biological sciences |
Experience & Service
Academic Appointments
Post-doctoral Fellow, Division of Mammalian Cell Biology and Development, The Rockefeller University, New York, NY, 2013 - 2018
Honors & Awards
| 2018 | Invited Speaker. 30th Annual Usha Mahajani Symposium, Salk Institute for Biological Studies |
| 2018 | K01 Career Development Award, NIAMS, NIH |
| 2018 | American Association for Cancer Research NextGen Star Award, AACR |
| 2018 | Cancer Prevention Research Institute of Texas, First-time Recruitment Award, Cancer Prevention Research of Texas |
| 2017 | Patent. No. 62/481,257 “Methods and Compositions for Detection and Treatment of Cancer” |
| 2017 | Irene Diamond Fund/AFAR Postdoctoral Transition Award in Aging |
| 2016 | Invited speaker. Cambridge Healthtech Institute’s 14th Annual Discovery on Target, Boston |
| 2015 | Keystone Symposia Scholarship, oral presentation, ncRNAs and cancer, Keystone, Colorado |
| 2015 | Invited speaker. Stem cells of the skin: targets and cure for disease, Santander, Spain |
| 2015 | Robertson Therapeutic Development Fund, Proof-of-Concept Award, Rockefeller University |
| 2014 | Department of Defense Breast Cancer Research Program Postdoctoral Fellowship Award, DoD |
| 2013 | Women & Science Postdoctoral Fellowship, Rockefeller University |
| 2012 | Proctor & Gamble Graduate Research Award, University of Illinois at Urbana-Champaign |
| 2010 | Cold Spring Harbor Asia-RNA biology. Oral presentation, Suzhou |
| 2004 | Wu Zhande Scholarship for Excellent Academic Performance, Tsinghua University |
Professional Memberships
Selected Publications
Peer-Reviewed Articles
- Ellis SJ, Gomez NC, Levorse J, Mertz AF, Ge Y, Fuchs E. Distinct modes of cell competition shape mammalian tissue morphogenesis. Nature 569(7757):497-502, 2019. e-Pub 2019. PMID: 31092920.
- Ge Y, Fuchs E. Stretching the limits: from homeostasis to stem cell plasticity in wound healing and cancer. Nat Rev Genet 19(5):311-325, 2018. e-Pub 2018. PMID: 29479084.
- Adam RC, Yang H, Ge Y, Lien WH, Wang P, Zhao Y, Polak L, Levorse J, Baksh SC, Zheng D, Fuchs E. Temporal Layering of Signaling Effectors Drives Chromatin Remodeling during Hair Follicle Stem Cell Lineage Progression. Cell Stem Cell 22(3):398-413.e7, 2018. e-Pub 2018. PMID: 29337183.
- Zhang L, Ge Y, Fuchs E. miR-125b can enhance skin tumor initiation and promote malignant progression by repressing differentiation and prolonging cell survival. Genes Dev 28(22):2532-46, 2014. PMID: 25403182.
- Khanna N, Ge Y, Chen J. MicroRNA-146b promotes myogenic differentiation and modulates multiple gene targets in muscle cells. PLoS One 9(6):e100657, 2014. e-Pub 2014. PMID: 24956113.
- Ge Y, Waldemer RJ, Nalluri R, Nuzzi PD, Chen J. Flt3L is a novel regulator of skeletal myogenesis. J Cell Sci 126(Pt 15):3370-9, 2013. e-Pub 2013. PMID: 23704355.
- Ge Y, Waldemer RJ, Nalluri R, Nuzzi PD, Chen J. RNAi screen reveals potentially novel roles of cytokines in myoblast differentiation. PLoS One 8(7):e68068, 2013. e-Pub 2013. PMID: 23844157.
- Ge Y, Chen J. Mammalian target of rapamycin (mTOR) signaling network in skeletal myogenesis. J Biol Chem 287(52):43928-35, 2012. e-Pub 2012. PMID: 23115234.
- Ge Y, Yoon MS, Chen J. Raptor and Rheb negatively regulate skeletal myogenesis through suppression of insulin receptor substrate 1 (IRS1). J Biol Chem 286(41):35675-82, 2011. e-Pub 2011. PMID: 21852229.
- Ge Y, Chen J. MicroRNAs in skeletal myogenesis. Cell Cycle 10(3):441-8, 2011. e-Pub 2011. PMID: 21270519.
- Ge Y, Sun Y, Chen J. IGF-II is regulated by microRNA-125b in skeletal myogenesis. J Cell Biol 192(1):69-81, 2011. e-Pub 2011. PMID: 21200031.
- Goodman CA, Miu MH, Frey JW, Mabrey DM, Lincoln HC, Ge Y, Chen J, Hornberger TA. A phosphatidylinositol 3-kinase/protein kinase B-independent activation of mammalian target of rapamycin signaling is sufficient to induce skeletal muscle hypertrophy. Mol Biol Cell 21(18):3258-68, 2010. e-Pub 2010. PMID: 20668162.
- Sun Y, Ge Y, Drnevich J, Zhao Y, Band M, Chen J. Mammalian target of rapamycin regulates miRNA-1 and follistatin in skeletal myogenesis. J Cell Biol 189(7):1157-69, 2010. e-Pub 2010. PMID: 20566686.
- Ge Y, Wu AL, Warnes C, Liu J, Zhang C, Kawasome H, Terada N, Boppart MD, Schoenherr CJ, Chen J. mTOR regulates skeletal muscle regeneration in vivo through kinase-dependent and kinase-independent mechanisms. Am J Physiol Cell Physiol 297(6):C1434-44, 2009. e-Pub 2009. PMID: 19794149.
Grant & Contract Support
| Title: | Functional Interrogation of Stem Cell Lineage Infidelity in Cancer |
| Funding Source: | Cancer Prevention & Research Institute of Texas (CPRIT) |
| Role: | Principal Investigator |
| Title: | New Faculty Grant |
| Funding Source: | Cancer Center Support Grant (CCSG) |
| Role: | Principal Investigator |
Patient Reviews
CV information above last modified June 26, 2024