Meet Yon Son Betty Kim, M.D., Ph.D.
Yon Son Betty Kim, MD, PhD, FRCSC, FAANS
Department of Neurosurgery, Division of Surgery
In the News
Study opens new avenue for immunotherapy drug development
Scientists develop novel mRNA delivery method using extracellular vesicles
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MD Anderson announces 2021 class of Andrew Sabin Family Fellows
Nanomedicine: Small particles with huge possibilities for cancer care
Present Title & Affiliation
Primary Appointment
Professor, Department of Neurosurgery, Division of Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX
Dual/Joint/Adjunct Appointment
Professor, Department of Neurosurgery, Division of Surgery, Baylor College of Medicine, Houston, TX
Research Interests
As a Physician Scientist, Dr. Kim’s laboratory takes a multidisciplinary approach to the research of solid tumors with a specific focus on malignant primary and metastatic brain tumors. Her work has been published in journals such as the New England Journal of Medicine, Nature, Nature Nanotechnology, Nature Biomedical Engineering, Nature Reviews Immunology and Nature Reviews Drug Discovery. Dr. Kim’s lab is interested in understanding the molecular cross-talk that occurs between tumor and stromal cells within the tumor immune-microenvironment, while also developing multiple patented therapeutic strategies to inhibit tumorigenesis. Her current research primarily focuses on finding new ways to promote immune recognition of glioma cells to boost the efficacies of cancer immunotherapies. Her group also pursues the identification of predictive and prognostic biomarkers for personalized medicine in the context of brain tumors.
Education & Training
Degree-Granting Education
2002 | McMaster University, Hamilton, CAN, MD, Faculty Medicine |
1998 | McGill University, Montreal, CAN, BSc (Hon), Anatomy and Cell Biology |
Postgraduate Training
2012-2013 | Clinical Fellowship, Skull Base Surgery, University of Texas MD Anderson Cancer Center, Houston, TX |
2011-2012 | Clinical Fellowship, Neurosurgical Oncology, University of Texas MD Anderson Cancer Center, Houston, TX |
2011-2012 | FRCSC, Neurologic Surgeon, Royal College of Surgeon, Canada |
2006-2009 | Clinician Investigator Program, Neurologic Surgery, University of Toronto, Toronto |
2005-2011 | Clinical Residency, Neurosurgery, University of Toronto, Toronto |
Board Certifications
2012 | Neurosurgery, Royal College of Physicians and Surgeons, Canada |
2002 | Medical Council of Canada/College of Surgeons of Ontario |
Experience & Service
Administrative Appointments/Responsibilities
Co-Director, Brain SPORE Animal Core, Department of Neurosurgery, University of Texas MD Anderson Cancer Center, Houston, TX, 2020 - Present
Other Appointments/Responsibilities
Board Member, Core Facility Oversight Board, UT MD Anderson, Houston, TN, 2022 - Present
Institutional Committee Activities
Member, Emerging Leader Workshop Committee, 2024 - Present
Member, Search Committee, Chairman of Plastic Surgery, 2023 - Present
Member, Core Facilities Oversight Board, 2022 - Present
Member, Gamma Knife Radiosurgery Review Panel, 2020 - Present
Member, Brain Metastasis Clinic, 2020 - Present
Member, Brain Tumor Program Tissue Utilization Committee, 2020 - Present
Co-Lead, Radiosurgery Review Committee, 2020 - Present
Honors & Awards
2023 | Regina Rogers Family Award, University of TX MD Anderson Cancer Center |
2021 | Sabin Family Foundation Fellowship Award, Sabin Family Foundation |
2016 | Forty Stars of Forty Under Florida - Florida Trend Magazine |
2012 | Detweiler Travelling Fellowship - Royal College of Physicians and Surgeons |
2010 | Sopman Humanitarian Award - University of Toronto |
2009 | National Research Award for Specialty Residents - Royal College of Physicians |
2009 | Mark Bernstein Award in Neurosurgery - University of Toronto, Toronto, Canada |
2009 | National Research Award - Canadian Federation of University Women, First place |
2009 | Top Gun American Association of Neurological Surgeons, 1st place |
2008 | Gallie-Bateman Research Award - Department of Surgery, University of Toronto |
2008 | Javenthey Soobiah Scholarship - University of Toronto School of Medicine |
2008 | Joseph M. West Family Memorial Scholarship - University of Toronto |
2008 | Post-Graduate Medicine Research Award - University of Toronto |
2008 | AANS/NREF Fellowship - American Association of Neurological Surgeons |
2008 | Restracomp Research Training Grant - Hospital for Sick Children, 1st place |
2008 | Thomas Morley Best Original Research - University of Toronto |
2008 | McKenzie Award - Canadian Neurological Sciences, Best neuroscience research |
2008 | Time Posters Fellowship - University of Toronto School of Medicine |
2008 | CIHR/Brain Star Award - Canadian Institutes of Health Research, Best research |
2005 | Heart and Stroke and Foundation of Canada - Medical Research Scholar Award |
2005 | Natural Sciences & Engineering Research Canada (NSERC) Grant |
2005 | Price Water House Research Excellence Award - University of Toronto |
2005 | Thomas L. Friedlich Award in Surgical Sciences Research - University of Toronto |
2005 | Charles F. Fell Scholarship - University of Toronto School of Medicine |
2005 | Joseph M. West Family Memorial Fund - University of Toronto |
2005 | Post-Graduate Medicine Research Award - University of Toronto |
2005 | Chisholm Memorial Research Fellowship |
Selected Publications
Peer-Reviewed Articles
- Wang Y, Schrank BR, Jiang W, Kim BYS. Learning what keeps nanomedicines in tumours. Nat Biomed Eng. e-Pub 2024. PMID: 39271934.
- Lee D, Huntoon K, Wang Y, Kang M, Lu Y, Jeong SD, Link TM, Gallup TD, Qie Y, Li X, Dong S, Schrank BR, Grippin AJ, Antony A, Ha J, Chang M, An Y, Wang L, Jiang D, Li J, Koong AC, Tainer JA, Jiang W, Kim BYS. Synthetic cationic helical polypeptides for the stimulation of antitumour innate immune pathways in antigen-presenting cells. Nat Biomed Eng. e-Pub 2024. PMID: 38641710.
- Wang Y, Deng W, Lee D, Yan L, Lu Y, Dong S, Huntoon K, Antony A, Li X, Ye R, Zhao Y, Zhao F, Schrank BR, Ha J, Kang M, Yang M, Gong P, Lorenzi PL, Tan L, Gallup TD, Tang SK, Yang Z, Li J, Sanford NN, Wang H, Kim BYS, Jiang W. Age-associated disparity in phagocytic clearance affects the efficacy of cancer nanotherapeutics. Nat Nanotechnol 19(2):255-263, 2024. e-Pub 2023. PMID: 37723279.
- Liu CC, Wang N, Chen Y, Inoue Y, Shue F, Ren Y, Wang M, Qiao W, Ikezu TC, Li Z, Zhao J, Martens Y, Doss SV, Rosenberg CL, Jeevaratnam S, Jia L, Raulin AC, Qi F, Zhu Y, Alnobani A, Knight J, Chen Y, Linares C, Kurti A, Fryer JD, Zhang B, Wu LJ, Kim BYS, Bu G. Cell-autonomous effects of APOE4 in restricting microglial response in brain homeostasis and Alzheimer's disease. Nat Immunol 24(11):1854-1866, 2023. e-Pub 2023. PMID: 37857825.
- Dong S, Liu X, Bi Y, Wang Y, Antony A, Lee D, Huntoon K, Jeong S, Ma Y, Li X, Deng W, Schrank BR, Grippin AJ, Ha J, Kang M, Chang M, Zhao Y, Sun R, Sun X, Yang J, Chen J, Tang SK, Lee LJ, Lee AS, Teng L, Wang S, Teng L, Kim BYS, Yang Z, Jiang W. Adaptive design of mRNA-loaded extracellular vesicles for targeted immunotherapy of cancer. Nat Commun 14(1):6610, 2023. e-Pub 2023. PMID: 37857647.
- Chiang CL, Ma Y, Hou YC, Pan J, Chen SY, Chien MH, Zhang ZX, Hsu WH, Wang X, Zhang J, Li H, Sun L, Fallen S, Lee I, Chen XY, Chu YS, Zhang C, Cheng TS, Jiang W, Kim BYS, Reategui E, Lee R, Yuan Y, Liu HC, Wang K, Hsiao M, Huang CF, Shan YS, Lee AS, James Lee L. Dual targeted extracellular vesicles regulate oncogenic genes in advanced pancreatic cancer. Nat Commun 14(1):6692, 2023. e-Pub 2023. PMID: 37872156.
- You Y, Tian Y, Yang Z, Shi J, Kwak KJ, Tong Y, Estania AP, Cao J, Hsu WH, Liu Y, Chiang CL, Schrank BR, Huntoon K, Lee D, Li Z, Zhao Y, Zhang H, Gallup TD, Ha J, Dong S, Li X, Wang Y, Lu WJ, Bahrani E, Lee LJ, Teng L, Jiang W, Lan F, Kim BYS, Lee AS. Intradermally delivered mRNA-encapsulating extracellular vesicles for collagen-replacement therapy. Nat Biomed Eng 7(7):887-900, 2023. e-Pub 2023. PMID: 36635419.
- Altan M, Wang Y, Song J, Welsh J, Tang C, Guha-Thakurta N, Blumenschein GR, Carter BW, Wefel JS, Ghia AJ, Yeboa DN, McAleer MF, Chung C, Woodhouse KD, McGovern SL, Wang C, Kim BYS, Weinberg JS, Briere TM, Elamin YY, Le X, Cascone T, Negrao MV, Skoulidis F, Ferrarotto R, Heymach JV, Li J. Nivolumab and ipilimumab with concurrent stereotactic radiosurgery for intracranial metastases from non-small cell lung cancer: analysis of the safety cohort for non-randomized, open-label, phase I/II trial. J Immunother Cancer 11(7), 2023. e-Pub 2023. PMID: 37402581.
- Huntoon K, Anderson SK, Ballman KV, Twohy E, Dooley K, Jiang W, An Y, Li J, von Roemeling C, Qie Y, Ross OA, Cerhan JH, Whitton AC, Greenspoon JN, Parney IF, Ashman JB, Bahary JP, Hadjipanayis C, Urbanic JJ, Farace E, Khuntia D, Laack NN, Brown PD, Roberge D, Kim BYS. Association of circulating markers with cognitive decline after radiation therapy for brain metastasis. Neuro Oncol 25(6):1123-1131, 2023. e-Pub 2022. PMID: 36472389.
- Oue H, Yamazaki Y, Qiao W, Yuanxin C, Ren Y, Kurti A, Shue F, Parsons TM, Perkerson RB, Kawatani K, Wang N, Starling SC, Roy B, Mosneag IE, Aikawa T, Holm ML, Liu CC, Inoue Y, Sullivan PM, Asmann YW, Kim BYS, Bu G, Kanekiyo T. LRP1 in vascular mural cells modulates cerebrovascular integrity and function in the presence of APOE4. JCI Insight 8(7), 2023. e-Pub 2023. PMID: 37036005.
- Lee DY, Huntoon K, Lux J, Kim BYS (Co-coresdponing), Jiang W. Engineering nanomaterial physical characteristics for cancer immunotherapy. Nature Reviews Bioengineering 1:499-517, 2023.
- Lu Y, Huntoon K, Lee D, Wang Y, Ha J, Qie Y, Li X, Schrank BR, Dong S, Gallup TD, Kang M, Zhao H, An Y, Yang Z, Li J, Kim BYS, Jiang W. Immunological conversion of solid tumours using a Bispecific nanobioconjugate for cancer immunotherapy. Nat Nanotechnol 17(12):1332-1341, 2022. e-Pub 2022. PMID: 36357792.
- Li X, Khorsandi S, Wang Y, Santelli J, Huntoon K, Nguyen N, Yang M, Lee D, Lu Y, Gao R, Kim BYS, de Gracia Lux C, Mattrey RF, Jiang W, Lux J. Cancer immunotherapy based on image-guided STING activation by nucleotide nanocomplex-decorated ultrasound microbubbles. Nat Nanotechnol 17(8):891-899, 2022. e-Pub 2022. PMID: 35637356.
- Liu CC, Zhao J, Fu Y, Inoue Y, Ren Y, Chen Y, Doss SV, Shue F, Jeevaratnam S, Bastea L, Wang N, Martens YA, Qiao W, Wang M, Zhao N, Jia L, Yamazaki Y, Yamazaki A, Rosenberg CL, Wang Z, Kong D, Li Z, Kuchenbecker LA, Trottier ZA, Felton L, Rogers J, Quicksall ZS, Linares C, Knight J, Chen Y, Kurti A, Kanekiyo T, Fryer JD, Asmann YW, Storz P, Wang X, Peng J, Zhang B, Kim BYS, Bu G. Peripheral apoE4 enhances Alzheimer’s pathology and impairs cognition by compromising cerebrovascular function. Nat Neurosci 25(8):1020-1033, 2022. e-Pub 2022. PMID: 35915180.
- Zamler DB, Shingu T, Kahn LM, Huntoon K, Kassab C, Ott M, Tomczak K, Liu J, Li Y, Lai I, Zorilla-Veloz R, Yee C, Rai K, Kim BYS, Watowich SS, Heimberger AB, Draetta GF, Hu J. Immune Landscape of a Genetically Engineered Murine Model of Glioma Compared with Human Glioma. JCI Insight 22(7):1-16, 2022. e-Pub 2022. PMID: 35653194.
- Hsieh RCE, Krishnan S, Wu RC, Boda AR, Liu A, Winkler M, Lea ST, Taniguchi C, Kim BYS, Chen J, Rudqvisst NP, Curran M. ATR-mediated CD47 and PD-L1 up-regulation restricts radiotherapy-induced immune priming and abscopal responses in colorectal cancer. Science Immunology 7(72), 2022. PMID: 35687697.
- Bishop AJ, Zheng J, Subramaniam A, Ghia AJ, Wang C, McGovern SL, Patel S, Guadagnolo BA, Mitra D, Farooqi A, Reardon MJ, Kim B, Guha-Thakurta N, Li J, Ravi V. Cardiac Angiosarcomas: Risk of Brain Metastasis and Hemorrhage Warrants Frequent Surveillance Imaging and Early Intervention. Am J Clin Oncol 45(6):258-263, 2022. e-Pub 2022. PMID: 35588225.
- Abdelfattah N, Kumar P, Wang C, Leu JS, Flynn WF, Gao R, Baskin DS, Pichumani K, Ijare OB, Wood SL, Powell SZ, Haviland DL, Parker Kerrigan BC, Lang FF, Prabhu SS, Huntoon KM, Jiang W, Kim BYS, George J, Yun K. Single-cell analysis of human glioma and immune cells identifies S100A4 as an immunotherapy target. Nat Commun 13(767):767, 2022. e-Pub 2022. PMID: 35140215.
- Yamazaki Y, Liu CC, Yamazaki A, Shue F, Martens YA, Chen Y, Qiao W, Kurti A, Oue H, Ren Y, Li Y, Aikawa T, Cherukuri Y, Fryer JD, Asmann YW, Kim BYS, Kanekiyo T, Bu G. Vascular ApoE4 Impairs Behavior by Modulating Gliovascular Function. Neuron 109(3):438-447.e6, 2021. e-Pub 2020. PMID: 33321072.
- Jiang W, Wang Y, Wargo JA, Lang FF, Kim BYS. Considerations for designing preclinical cancer immune nanomedicine studies. Nat Nanotechnol 16(1):6-15, 2021. e-Pub 2020. PMID: 33349682.
- Deng W, Wang Y, Liu X, Liu J, Wang L, Yang Z, Yang M, An Y, Tang C, Sanford NN, Kim BYS, Jiang W. Assessment of Trends in Second Primary Cancers in Patients with Metastatic Melanoma From 2005 to 2016. JAMA Netw Open 3(12):e2028627, 2020. e-Pub 2020. PMID: 33295975.
- von Roemeling CA, Wang Y, Qie Y, Yuan H, Zhao H, Liu X, Yang Z, Yang M, Deng W, Bruno KA, Chan CK, Lee AS, Rosenfeld SS, Yun K, Johnson AJ, Mitchell DA, Jiang W, Kim BYS. Therapeutic modulation of phagocytosis in glioblastoma can activate both innate and adaptive antitumour immunity. Nat Commun 11(1):1508, 2020. e-Pub 2020. PMID: 32198351.
- Yang Z, Shi J, Xie J, Wang Y, Sun J, Liu T, Zhao Y, Zhao X, Wang X, Ma Y, Malkoc V, Chiang C, Deng W, Chen Y, Fu Y, Kwak KJ, Fan Y, Kang C, Yin C, Rhee J, Bertani P, Otero J, Lu W, Yun K, Lee AS, Jiang W, Teng L, Kim BYS, Lee LJ. Large-scale generation of functional mRNA-encapsulating exosomes via cellular nanoporation. Nat Biomed Eng 4(1):69-83 (Journal Cover), 2020. e-Pub 2019. PMID: 31844155.
- Feng M, Jiang W, Kim BYS, Zhang CC, Fu YX, Weissman IL. Phagocytosis checkpoints as new targets for cancer immunotherapy. Nat Rev Cancer 19(10):568-586, 2019. e-Pub 2019. PMID: 31462760.
- Leong HS, Butler KS, Brinker CJ, Azzawi M, Conlan S, Dufés C, Owen A, Rannard S, Scott C, Chen C, Dobrovolskaia MA, Kozlov SV, Prina-Mello A, Schmid R, Wick P, Caputo F, Boisseau P, Crist RM, McNeil SE, Fadeel B, Tran L, Hansen SF, Hartmann NB, Clausen LPW, Skjolding LM, Baun A, Ågerstrand M, Gu Z, Lamprou DA, Hoskins C, Huang L, Song W, Cao H, Liu X, Jandt KD, Jiang W, Kim BYS, Wheeler KE, Chetwynd AJ, Lynch I, Moghimi SM, Nel A, Xia T, Weiss PS, Sarmento B, das Neves J, Santos HA, Santos L, Mitragotri S, Little S, Peer D, Amiji MM, Alonso MJ, Petri-Fink A, Balog S, Lee A, Drasler B, Rothen-Rutishauser B, Wilhelm S, Acar H, Harrison RG, Mao C, Mukherjee P, Ramesh R, McNally LR, Busatto S, Wolfram J, Bergese P, Ferrari M, Fang RH, Zhang L, Zheng J, Peng C, Du B, Yu M, Charron DM, Zheng G, Pastore C. On the issue of transparency and reproducibility in nanomedicine. Nat Nanotechnol 34(8):811, 2019. PMID: 31270452.
- Chen Y, Liu X, Yuan H, Yang Z, von Roemeling CA, Qie Y, Zhao H, Wang Y, Jiang W, Kim BYS. Therapeutic remodeling of the tumor microenvironment enhances nanoparticle delivery. Adv Sci (Weinh) 6(5):1802070, 2019. e-Pub 2019. PMID: 30886813.
- Liu Z, Jiang W, Nam J, Moon JJ, Kim BYS. Immunomodulating Nanomedicine for Cancer Therapy. Nano Letters 18(11):6655-6659, 2018. e-Pub 2018. PMID: 30185039.
- Ioannidis JPA, Kim BYS, Trounson A. How to design preclinical studies in nanomedicine and cell therapy to maximize the prospects of clinical translation. Nature Biomedical Engineering 2(11):797-809, 2018. e-Pub 2018. PMID: 30931172.
- Zheng X, Fang Z, Liu X, Deng S, Zhou P, Wang X, Zhang C, Yin R, Hu H, Chen X, Han Y, Zhao Y, Lin SH, Qin S, Wang X, Kim BY, Zhou P, Jiang W, Wu Q, Huang Y. Increased vessel perfusion predicts the efficacy of immune checkpoint blockade. Journal of Clinical Investigation 128(5):2104-2115, 2018. e-Pub 2018. PMID: 29664018.
- Huang Y, Kim BYS, Chan CK, Hahn SM, Weissman IL, Jiang W. Improving immune-vascular crosstalk for cancer immunotherapy. Nature Reviews Immunology 18(3):195-203, 2018. e-Pub 2018. PMID: 29332937.
- Yuan H, Jiang W, von Roemeling CA, Qie Y, Liu X, Chen Y, Wang Y, Wharen RE, Yun K, Bu G, Knutson KL, Kim BYS. Multivalent bispecific nanobioconjugate engager for targeted cancer immunotherapy. Nat Nanotechnol 12(8):763-769, 2017. e-Pub 2017. PMID: 28459470.
- Jiang W, Yuan H, Chan CK, von Roemeling CA, Yan Z, Weissman IL, Kim BYS. Lessons from Immuno-Oncology: A New Era for Cancer Nanomedicine. Nature Reviews Drug Discovery 16(6):369-370, 2017. e-Pub 2017. PMID: 28303024.
- Jiang W, von Roemeling C, Qie Y, Chen Y, Liu X, Chen J, Kim BYS. Designing nanomedicine for immuno-oncology. Nature Biomedical Engineering 1(0029):1, 2017. PMID: 28303024.
- Qie Y, Yuan H, von Roemeling CA, Chen Y, Liu X, Shih KD, Knight JA, Tun HW, Wharen RE, Jiang W, Kim BY. Surface modification of nanoparticles enables selective evasion of phagocytic clearance by distinct macrophage phenotypes. Scientific Report 6:26269, 2016. e-Pub 2016. PMID: 27197045.
- Jiang W, Chan CK, Weissman IL, Kim BYS (co-corresponding author), Hahn SM. Immunogenic Priming of Tumor Microenvironment. Trends in Cancer (Cell Press) 1(11), 2016. PMID: 28741502.
- Kim BY, Rutka JT, Chan WC. Nanomedicine. New England Journal of Medicine Cited 1300 times. 363(25):2434-43, 2010. PMID: 21158659.
- Kim BY, Jiang W, Oreopoulos J, Yip CM, Rutka JT, Chan WC. Biodegradable quantum dot nanocomposites enable live cell labeling and imaging of cytoplasmic targets. Nano Letters 8(11):3887-92, 2008. e-Pub 2008. PMID: 18816147.
- Jiang W, Kim BY, Rutka JT, Chan WC. Nanoparticle-mediated cellular response is size-dependent. Nature Nanotechnology. Featured in Nature Nanotechnology 15 Year Anniversary Issue on October 2021 as one of the most impactful nanomedicine study. Cited 3012 times. 3(3):145-50, 2008. e-Pub 2008. PMID: 18654486.
- Zhu S, Stavrovskaya IG, Drozda M, Kim BY, Ona V, Li M, Sarang S, Liu AS, Hartley DM, Wu DC, Gullans S, Ferrante RJ, Przedborski S, Kristal BS, Friedlander RM. Minocycline inhibits cytochrome c release and delays progression of amyotrophic lateral sclerosis in mice. Nature 417(6884):74-8, 2002. PMID: 11986668.
- Lee DY, Huntoon K, Wang Y, Lu Y, Qie Y, Li X, Dong S, Yang Z, Wang L, Li J, Koong A, Jiang W, Kim BYS. Synthetic cationic helical polypeptide as a multipotent innate immune sensor activator for cancer immunotherapy. Nature Biomedical Engineering.
Invited Articles
- Leong HS, Butler KS, Brinker CJ, Azzawi M, Conlan S, Dufès C, Owen A, Rannard S, Scott C, Chen C, Dobrovolskaia MA, Kozlov SV, Prina-Mello A, Schmid R, Wick P, Caputo F, Boisseau P, Crist RM, McNeil SE, Fadeel B, Tran L, Hansen SF, Hartmann NB, Clausen LPW, skjolding LM, Baun A, Ågerstrand M, Gu Z, Lamprou DA, Hoskins C, Huang L, Song W, Cao H, Liu X, Jandt KD, Jiang W, Kim BYS, Wheeler KE, Chetwynd AJ, Lynch I, Moghimi SM, Nel A, Xia T, Weiss PS, Sarmento B, das Neves J, Santos HA, Santos L, Mitragotri S, Little S, Peer D, Amiji MM, Alonso MJ, Petri-Fink A, Balog S, Lee A, Drasler B, Rothen-Rutishauser B, Wilhelm S, Acar H, Harrison R.G, Mao C, Mukherjee P, Ramesh R, McNally LR, Busatto S, Wolfram J, Bergese P, Ferrari M, Fang RH, Zhang L, Zheng J, Peng C, Du B, Yu M, Charron DM, Zheng G, Pastore C.. On the issue of transparency and reproducibility in nanomedicine. Nature Nanotechnology 14(7):629-635, 2019.
- Huntoon K, Jiang W, Kim BYS. Waking Immune-Resistant Tumors with NEDdlyation Truly is Divine. Journal of Clinical Investigation. PMID: 36787255.
Grant & Contract Support
Title: | SPORE in Brain Cancer – Animal Core |
Funding Source: | NIH/NCI |
Role: | Project Leader |
Title: | Therapeutic targeting of multiple glioblastoma phagocytosis checkpoints using a novel bispecific antibody |
Funding Source: | NIH/NINDS |
Role: | Co-Investigator |
Title: | S100a4 Mediated Immune Suppression in GBM |
Funding Source: | NIH/NINDS |
Role: | Co-Investigator |
Title: | Break Through Cancer Glioblastoma Team |
Funding Source: | Research Alliance between MIT, Dana Farber, MD Anderson, Memorial Sloan Kettering and Johns Hopkins University |
Role: | Co-Investigator |
Title: | Spatio-temporal activation of the STING pathway using acoustically responsive materials to promote anti-tumor response |
Funding Source: | NIH/NCI |
Role: | Co-Investigator |
Title: | Microbial-inspired STING Activation for Glioblastoma Immunotherapy |
Funding Source: | Uncle Kory Foundation |
Role: | Principal Investigator |
Title: | Microbial mediated STING Activation for Glioblastoma Immunotherapy |
Funding Source: | American Brain Tumor Association |
Role: | Mentor |
Title: | Glioblastoma immunotherapy with dual phagocytosis checkpoint blockade |
Funding Source: | American Cancer Association-Research Scholar Grant |
Role: | Co-Investigator |
Title: | Reversing aging-associated resistance to cancer immunotherapy |
Funding Source: | Cancer Prevention & Research Institute of Texas (CPRIT) |
Role: | Co-Principal Investigator |
Title: | In vivo chimeric antigen receptor macrophage (ChARMs) for cancer immunotherapy |
Funding Source: | Cancer Prevention & Research Institute of Texas (CPRIT) |
Role: | Co-Principal Investigator |
Title: | Engineering in vivo chimeric antigen receptor macrophages (CARMs) using mRNA-exosomes for cancer immunotherapy |
Funding Source: | NIH/NCI |
Role: | Co-Principal Investigator |
Patient Reviews
CV information above last modified November 20, 2024