Meet Wayne Hofstetter, M.D.
Wayne L. Hofstetter, M.D.
Department of Thoracic and Cardiovascular Surgery, Division of Surgery
About Dr. Hofstetter
Wayne L. Hofstetter, M.D., is currently Professor in the Department of Thoracic and Cardiovascular Surgery and serves as Director of the Esophageal Surgery Program.
A graduate of the University of Southern California Medical School, Dr. Hofstetter focused on thoracic surgical disease, completing fellowships in esophageal and foregut surgeries at the University of Southern California, and then thoracic oncology at M. D. Anderson Cancer Center. Broadly trained as a cardiothoracic surgeon and thoracic oncologist at the Texas Heart Institute, he now devotes a great deal of his work to esophageal cancer and lung cancer. At M. D. Anderson, he formed a strong network of clinicians with specific interests in esophageal diseases. A multidisciplinary group emerged under his able leadership, and together, physicians from other specialties like Gastrointestinal Medical Oncology, Radiation Oncology, and Gastroenterology collaborate closely to treat esophageal cancer patients.
Dr. Hofstetter is a leading proponent of surgical and multidisciplinary approaches to esophageal cancer and minimally invasive approaches to lung cancer, bringing to the institution his unique clinical skills in MIS approaches to thoracic surgery.
Board certified both by the American Board of Surgery and the American Board of Thoracic Surgery, Dr. Hofstetter is nationally and internationally involved in a host of clinical and scientific endeavors with membership in several organizations, the Society for Surgery of the Alimentary Tract, the General Thoracic Surgical Club, the American Association for Thoracic Surgery, including the Society of Thoracic Surgeons, and the International Association for the Study of Lung Cancer. His research, which forms a vital part of his academic role, has led to numerous peer-reviewed publications, notably in such journals as the Journal of Thoracic and Cardiovascular Surgery, Annals of Thoracic Surgery, and Cancer.
Present Title & Affiliation
Primary Appointment
Deputy Chair, Department of Thoracic and Cardiovascular Surgery, Division of Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX
Professor, Department of Thoracic and Cardiovascular Surgery, Division of Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX
Director, Esophageal Surgery Program, Department of Thoracic and Cardiovascular Surgery - Research, The University of Texas MD Anderson Cancer Center, Houston, TX
Education & Training
Degree-Granting Education
| 1993 | University of Southern California Medical School, Los Angeles, CA, USA, MD, MD |
| 1989 | University of California at Davis, Davis, CA, USA, BA, Economics |
Postgraduate Training
| 2002-2002 | Fellow, Cardiovascular Surgery, Texas Heart Institute, Houston, TX |
| 2001-2001 | Fellow, Thoracic & Cardiovascular Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX |
| 2000-2000 | Fellow, Cardiovascular Surgery, Texas Heart Institute, Houston, TX |
| 1999-2000 | Fellow, Thoracic and Esophageal, USC University Hospital, Los Angeles, CA |
| 1996-1997 | Research Fellowship, LAC+USC, Department of Surgery,, Los Angeles, CA |
| 1994-1999 | Resident, General Surgery, LAC+USC Medical Center/USC University Hospital, Kenneth J. Norris Cancer Center, Los Angeles, CA |
| 1993-1994 | Intern, Surgery, The Los Angeles County + University of Southern California (LAC+USC) Medical Center, Los Angeles, CA |
Board Certifications
| 2002 | American Board of Thoracic Surgery |
| 2000 | American Board of Surgery |
Experience & Service
Academic Appointments
Associate Professor, Department of Thoracic and Cardiovascular Surgery, Division of Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX, 2007 - 2013
Assistant Professor, Department of Thoracic and Cardiovascular Surgery, Division of Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX, 2004 - 2007
Assistant Professor, Division of Departments of Thoracic Surgery and Surgical Oncology, David Geffen UCLA School of Medicine, Los Angeles, CA, 2002 - 2004
Instructor, LAC+USC County Hospital, Los Angeles, CA, 1999 - 2000
Junior Faculty, Kenneth Norris Jr. Cancer Center and USC University Hospital, Los Angeles, CA, 1999 - 2000
Institutional Committee Activities
Member, Credential Committee of the Medical Staff, 2010 - Present
Member, Faculty Senate, 2009 - Present
Member, VAT Committee, 2009 - Present
Member, Medical Practice Subcommittee, 2005 - 2008
Director, Esophageal Tumor Board, 2004 - Present
Honors & Awards
| 2014 | Best Doctors in America, MD Anderson Cancer Center Physicians |
| 2013 | Best Doctors in America, MD Anderson Cancer Center Physicians |
| 2011 | Dwight C. McGoon Award, Thoracic Surgery Resident's Association (TSRA) |
| 2010 | Dwight C. McGoon Award, Thoracic Surgery Residents Association (TSRA) |
| 2006 | The Surgery Chief Resident Teaching Award, The University of Texas Houston Medical School, Department of Surgery |
| 2005 | Robert Ginsberg Surgical Oncology Award, The Radiation Therapy Oncology Group |
Professional Memberships
Selected Publications
Peer-Reviewed Articles
- Harada K, Hwang H, Wang X, Abdelhakeem A, Iwatsuki M, Blum Murphy MA, Maru DM, Weston B, Lee JH, Rogers JE, Thomas I, Shanbhag N, Zhao M, Bhutani MS, Nguyen QN, Swisher SG, Ikoma N, Badgwell BD, Hofstetter WL, Ajani JA. Frequency and Implications of Paratracheal Lymph Node Metastases In Resectable Esophageal Or Gastroesophageal Junction Adenocarcinoma. Ann Surg 273(4):751-757, 2021. e-Pub 2019. PMID: 31188215.
- Harada K, Wu CC, Wang X, Mizrak Kaya D, Amlashi FG, Iwatsuki M, Blum Murphy MA, Maru DM, Weston B, Lee JH, Rogers JE, Thomas I, Shanbhag N, Bhutani MS, Hofstetter WL, Nguyen QN, Ajani JA. Total Lesion Glycolysis Assessment Identifies a Patient Fraction With A High Cure Rate Among Esohageal Adenocarcinoma Patients Treated With Definitive Chemoradiation. Ann Surg 272(2):311-318, 2020. e-Pub 2019. PMID: 32675544.
- Shewale JB, Correa AM, Brown EL, Leon-Novelo LG, Nyitray AG, Antonoff MB, Hofstetter WL, Mehran RJ, Rice DC, Walsh GL, Roth J, Vaporciyan AA, Swisher SG, Sepesi B. Time Trends of Perioperative Outcomes in Early-Stage Non-Small Cell Lung Cancer Resection Patients. Ann Thorac Surg 109(2):404-411, 2020. e-Pub 2019. PMID: 31539514.
- Nelson DB, Mitchell KG, Weston BR, Betancourt S, Maru D, Rice DC, Mehran RJ, Sepesi B, Antonoff MB, Walsh GL, Swisher SG, Roth JA, Vaporciyan AA, Blum M, Hofstetter WL. Should Endoscopic Mucosal Resection Be Attempted for cT2N0 Esophageal Cancer?. Dis Esophagus 32(10):1-6, 2019. e-Pub 2019. PMID: 30888418.
- Mitchell KG, Ikoma N, Nelson DB, Maru DM, Erasmus JJ, Weston BR, Vaporciyan AA, Antonoff MB, Mehran RJ, Rice DC, Roth JA, Swisher SG, Sepesi B, Walsh GL, Correa AM, Das P, Blum MA, Badgwell BD, Hofstetter WL. Mediastinal Nodal Involvement After Neoadjuvant Chemoradiation For Siewert II/III Adenocarcinoma. Ann Thorac Surg 108(3):845-851, 2019. e-Pub 2019. PMID: 31102632.
- Nelson DB, Mehran RJ, Mitchell KG, Rajaram R, Correa AM, Bassett RL, Antonoff MB, Hofstetter WL, Roth JA, Sepesi B, Swisher SG, Walsh GL, Vaporciyan AA, Rice DC. Robotic Assisted Lobectomy For Non-Small Cell Lung Cancer. Ann Thorac Surg 108(2):370-376, 2019. e-Pub 2019. PMID: 31004583.
- Nelson DB, Tayob N, Mitchell KG, Correa AM, Hofstetter WL, Sepesi B, Walsh GL, Vaporciyan AA, Swisher SG, Antonoff MB, Roth JA, Rice DC, Vauthey JN, Mehran RJ. Surgical Margins and Risk Of Local Recurrence After Wedge Resection Of Colorectal Pulmonary Metastases. J Thorac Cardiovasc Surg 157(4):1648-1655, 2019. e-Pub 2018. PMID: 30635188.
- Nelson DB, Rice DC, Mitchell KG, Tsao AS, Vaporciyan AA, Antonoff MB, Hofstetter WL, Walsh GL, Swisher SG, Roth JA, Gomez DR, Mehran RJ, Sepesi B. Defining The Role Of Adjuvant Radiotherapy For Malignant Pleural Mesothelioma; A Propensity-Matched Landmark Analysis Of the National Cancer Database. J Thorac Dis 11(4):1269-1278, 2019. PMID: 31179069.
- Luo W, Hofstetter WL, Tan D. Gastroesophageal Junction Paneth Cell Carcinoma With Extensive Cystic and Secretory Features - Case Report and Literature Review. Diagn Pathol 14(1):1, 2019. e-Pub 2019. PMID: 30621725.
- Hofstetter WL. Maximizing Response and Outcomes In Multimodality Therapy For Locally Advanced Esophageal Adenocarcinoma. J Thorac Cardiovasc Surg. e-Pub 2018.
- Kim MP, Correa AM, Hofstetter WL, Mehran RJ, Rice DC, Roth JA, Vaporciyan AA, Walsh GL, Erasmus JJ, Swisher SG. Occult Stage IIIA-N2 Patients Have Excellent Overall Survival With Initial Surgery. J Thorac Dis 10(12):6670-6676, 2018. PMID: 30746212.
- Rajaram R, Hofstetter WL. Mucosal Ablation Techniques for Barrett's Esophagus and Early Esophageal Cancer. Thorac Surg Clin 28(4):473-480, 2018. PMID: 30268293.
- Hofstetter WL. The Artificial Trachea: A Mission of Creativity, Perspiraction and Perseverance. J Thorac Cardiovasc Surg 156(3):1273-1274, 2018. e-Pub 2018. PMID: 29934005.
- Van Haren RM, Mehran RJ, Mena GE, Correa AM, Antonoff MB, Baker CM, Woodard TC, Hofstetter WL, Roth JA, Sepesi B, Swisher SG, Vaporciyan AA, Walsh GL, Rice DC. Enhanced Recovery Decreases Pulmonary and Cardiac Complications Following Thoracotomy for Lung Cancer. Ann Thorac Surg 106(1):272-279, 2018. e-Pub 2018. PMID: 29530770.
- Nelson DB, Godoy MCB, Benveniste MF, Shewale JB, Spicer JD, Mitchell KG, Hofstetter WL, Mehran RJ, Rice DC, Sepesi B, Walsh GL, Vaporciyan AA, Swisher SG, Roth JA, Antonoff MB. Clinicoradiographic Predictors Of Aggressive Biology In Lung Cancer With Ground Gladd Components. Ann Thorac Surg 106(1):235-241, 2018. e-Pub 2018. PMID: 29534957.
- Goense L, Merrell KW, Arnett AL, Hallemeier CL, Meijer GJ, Ruurda JP, Hofstetter WL, van Hillegersberg R, Lin SH. Validation of a Nomogram Predicting Survival After Trimodality Therapy for Esophageal Cancer. Ann Thorc Surg, 2018. e-Pub 2018.
- Ikoma N, Hofstetter WL, Estrella JS, Das P, Minsky BD, Fournier KF, Mansfield PF, Ajani JA, Badgwell BD. The ypT Category Does Not Impact Overall Survival In Node Negative Gastric Cancer. J Surg Oncol 117(8):1721-1728, 2018. e-Pub 2018. PMID: 29949666.
- Cascone T, Gold KA, Swisher SG, Liu DD, Fossella FV, Sepesi B, Pataer A, Weissferdt A, Kalhor N, Vaporciyan AA, Hofstetter WL, Wistuba II, Heymach JV, Kim ES, William WN Jr. Induction Cisplatin Docetaxel Followed by Surgery and Erlotinib in Non-Small Cell Lung Cancer. Ann Thorac Surg 105(2):418-424, 2018. e-Pub 2017. PMID: 29217088.
- Goltsov AA, Fang B, Pandita TK, Maru DM, Swisher SG, Hofstetter WL. HER2 Confers Resistance to Foretinib Inhibition of MET-Amplified Esophageal Adenocarcinoma Cells. Ann Thorc Surg 105(2):363-370, 2018. PMID: 29223420.
- Sepesi B, Ye Y, Mitchell KG, Zhang L, Gu J, Li L, Antonoff MB, Hofstetter WL, Rice DC, Mehran RJ, Walsh GL, Vaporciyan AA, Swisher SG, Roth JA, Wu X. Genetic Variants In Cytokine Signaling Pathways And Clinical Outcomes in Early-Stage Lung Cancer Patients Prognostic Value of PD-L1 mRNA Sequencing. J Thorac Cardiovasc Surg. e-Pub 2018. PMID: 29548588.
- Atay SM, Correa AM, Hofstetter WL, Mehran RJ, Rice DC, Roth JA, Sepesi B, Swisher SG, Vaporciyan AA, Walsh G, Antonoff MB. Perioperative Outcomes of Patients Undergoing Lobectomy on Clopidogrel. Ann Thorac Surg 104(6):1821-1828, 2017. e-Pub 2017.
- Betancourt Cuellar SL, Heller L, Palacio DP, Hofstetter WL, Marom EM. Intra and Extra-Thoracic Muscle Flaps and Chest Wall Reconstruction Following Resection of Thoracic Tumors. Semin Ultrasound CT MR 38(6):604-615, 2017. e-Pub 2017.
- Nelson DB, Rice DC, Niu J, Atay S, Vaporciyan AA, Antonoff M, Hofstetter WL, Walsh GL, Swisher SG, Roth JA, Tsao A, Gomez D, Giordano SH, Mehran RJ, Sepesi B. Long-Term Survival Outcomes Of Cancer-Directed Surgery For Malignant Pleural Mesothelioma: Propensity Score Matching Analysis. Clin Oncol 35(29):3354-3362, 2017. e-Pub 2017. PMID: 28817374.
- Bassuner JK, Rice DC, Antonoff MB, Correa AM, WalshGL, Vaporciyan AA, Garg N, Sepesi B, Swisher SG, Hofstetter WL, Roth JA, Mehran RJ. Polytetrafluoroethylene or Acellular Dermal Matrix for Diaphragmatic Reconstruction?. Ann Thorac Surg 103(6):1710-1714, 2017. e-Pub 2017. PMID: 28366460.
- Shimodaira Y, Slack RS, Harada K, Bhutani MS, Elimova E, Staerkel GA, Sneige N, Erasmus J, Shiozaki H, Charalampakis N, Planjery V, Kaya DM, Amlashi FG, Blum MA, Skinner HD, Minsky BD, Maru DM, Hofstetter WL, Swisher SG, Mares JE, Rogers JE, Lin QD, Ross WA, Weston B, Lee JH, Ajani JA. Utility of Endoscopic Ultrasound-guided Fine-needle Aspiration of Regional Lymph Nodes That Are Proximal To And Far From The Primary Distal Esophageal Carcinoma. Oncotarget 8(45):79356-79365, 2017. e-Pub 2017. PMID: 29108314.
- Tong Z, Chatterjee D, Deng D, Veeranki O, Mejia A, Ajani JA, Hofstetter WL, Lin S, Guha S, Kopetz S, Krishnan S, Maru D. Antitumor Effects of Cyclin Dependent Kinase 9 Inhibition in Esophageal Adenocarcinoma. Oncotarget 8(17):28696-28710, 2017. e-Pub 2017. PMID: 28404924.
- Swisher SG, Moughan J, Komaki RU, Ajani JA, Wu TT, Hofstetter WL, Konski AA, Willett CG. Final Results of NRG Oncology RTOG 0246: An Organ-Preserving Selective Resection Strategy in Esophageal Cancer Patients Treated with Definitive Chemoradiation. J Thorac Oncol 12(2):368-374, 2017. e-Pub 2016. PMID: 27729298.
- Rice TW, Ishwaran H, Kelsen DP, Hofstetter WL, Apperson-Hansen C, Blackstone EH, Worldwide Esophageal Cancer Collaboration Investigators. Recommendations for Neoadjuvant Pathologic Staging (ypTNM) of Cancer of The Esophagus and Esophagogastric Junction for the 8th Edition AJCC/UICC Staging Manuals. Dis Esophagus 29(8):906-912, 2016. PMID: 27905170.
- Rice TW, Lerut TE, Orringer MB, Chen LQ, Hofstetter WL, Smithers BM, Rusch VW, van Lanschot J, Chen KN, Davies AR, D'Journo XB, Kesler KA, Luketich JD, Ferguson MK, Räsänen JV, van Hillegersberg R, Fang W, Durand L, Allum WH, Cecconello I, Cerfolio RJ, Pera M, Griffin SM, Burger R, Liu JF, Allen MS, Law S, Watson TJ, Darling GE, Scott WJ, Duranceau A, Denlinger CE, Schipper PH, Ishwaran H, Apperson-Hansen C, DiPaola LM, Semple ME, Blackstone EH. Worldwide Esophageal Cancer Collaboration: neoadjuvant pathologic staging data. Dis Esophagus 29(7):715-723, 2016. PMID: 27731548.
- Wang J, Myles B, Wei C, Chang JY, Hofstetter WL, Ajani JA, Swisher SG, Cox JD, Komaki R, Liao Z, Lin SH. Obesity and outcomes in patients treated with chemoradiotherapy for esophageal carcinoma. Dis Esophagus 27(2):168-75, 2014. e-Pub 2013. PMID: 23621168.
- Francis AM, Sepesi B, Correa AM, Blum MA, Erasmus JJ, Lee JH, Maru DM, Mehran RJ, Rice DC, Roth JA, Vaporciyan AA, Walsh GL, Welsh JW, Swisher SG, Hofstetter WL, University of Texas MD Anderson Esophageal Cancer Group. The Influence of Histopathologic Tumor Vability on Long-term Survival and Recurrence Rates Following Neoadjuvant Therapy for Esophageal Adenocarcinoma. Ann Surg 258(3):500-7, 2013. PMID: 24022442.
- Cheedella NK, Suzuki A, Xiao L, Hofstetter WL, Maru DM, Taketa T, Sudo K, Blum MA, Lin SH, Welch J, Lee JH, Bhutani MS, Rice DC, Vaporciyan AA, Swisher SG, Ajani JA. Association between clinical complete response and pathological complete response after preoperative chemoradiation in patients with gastroesophageal cancer: analysis in a large cohort. Ann Oncol 24(5):1262-6, 2013. e-Pub 2012. PMID: 23247658.
- Taketa T, Xiao L, Sudo K, Suzuki A, Wadhwa R, Blum MA, Lee JH, Weston B, Bhutani MS, Skinner H, Komaki R, Maru DM, Rice DC, Swisher SG, Hofstetter WL, Ajani JA. Propensity-based matching between esophagogastric cancer patients who had surgery and who declined surgery after preoperative chemoradiation. Oncology 85(2):95-9, 2013. e-Pub 2013. PMID: 23860252.
- Wadhwa R, Taketa T, Correa AM, Sudo K, Campagna MC, Blum MA, Komaki R, Skinner H, Lee JH, Bhutani MS, Weston B, Maru DM, Rice DC, Swisher S, Hofstetter WL, Ajani JA. Incidence of brain metastases after trimodality therapy in patients with esophageal or gastroesophageal cancer: implications for screening and surveillance. Oncology 85(4):204-7, 2013. e-Pub 2013. PMID: 24051869.
- Hayashi Y, Xiao L, Suzuki A, Blum MA, Sabloff B, Taketa T, Maru DM, Welsh J, Lin SH, Weston B, Lee JH, Bhutani MS, Hofstetter WL, Swisher SG, Ajani JA. A nomogram associated with high probability of malignant nodes in the surgical specimen after trimodality therapy of patients with oesophageal cancer. Eur J Cancer 48(18):3396-404, 2012. e-Pub 2012. PMID: 22853875.
- Lin SH, Wang L, Myles B, Thall PF, Hofstetter WL, Swisher SG, Ajani JA, Cox JD, Komaki R, Liao Z. Propensity Score-based Comparison of Long-term Outcomes With 3-Dimensional Conformal Radiotherapy vs Intensity-Modulated Radiotherapy for Esophageal Cancer. Int J Radiat Oncol Biol Phys 84(5):1078-85, 2012. e-Pub 2012. PMID: 22867894.
- Blackmon SH, Stephens EH, Correa AM, Hofstetter W, Kim MP, Mehran RJ, Rice DC, Roth JA, Swisher SG, Walsh GL, Vaporciyan AA. Predictors of recurrent pulmonary metastases and survival after pulmonary metastasectomy for colorectal cancer. Ann Thorac Surg 94(6):1802-9, 2012. e-Pub 2012. PMID: 23063195.
- Sepesi B, Swisher SG, Walsh GL, Correa A, Mehran RJ, Rice D, Roth J, Vaporciyan A, Hofstetter WL. Omental reinforcement of the thoracic esophagogastric anastomosis: An analysis of leak and reintervention rates in patients undergoing planned and salvage esophagectomy. J Thorac Cardiovasc Surg 144(5):1146-51, 2012. e-Pub 2012. PMID: 22939861.
- Ajani JA, Correa AM, Hofstetter WL, Rice DC, Blum MA, Suzuki A, Taketa T, Welsh J, Lin SH, Lee JH, Bhutani MS, Ross WA, Maru DM, Macapinlac HA, Erasmus J, Komaki R, Mehran RJ, Vaporciyan AA, Swisher SG. Clinical parameters model for predicting pathologic complete response following preoperative chemoradiation in patients with esophageal cancer. Ann Oncol 23(10):2638-42, 2012. e-Pub 2012. PMID: 22831985.
- Marks JL, Hofstetter WL. Esophageal reconstruction with alternative conduits. Surg Clin North Am 92(5):1287-129, 2012. e-Pub 2012. PMID: 23026282.
- Thomas RM, Truty MJ, Nogueras-Gonzalez GM, Fleming JB, Vauthey JN, Pisters PW, Lee JE, Rice DC, Hofstetter WL, Wolff RA, Varadhachary GR, Wang H, Katz MH. Selective Reoperation for Locally Recurrent or Metastatic Pancreatic Ductal Adenocarcinoma Following Primary Pancreatic Resection. J Gastrointest Surg 16(9):1696-704, 2012. e-Pub 2012. PMID: 22644446.
- Lin SH, Komaki R, Liao Z, Wei C, Myles B, Guo X, Palmer M, Mohan R, Swisher SG, Hofstetter WL, Ajani JA, Cox JD. Proton Beam Therapy and Concurrent Chemotherapy for Esophageal Cancer. Int J Radiat Oncol Biol Phys 83(3):e345-51, 2012. e-Pub 2012. PMID: 22417808.
- Amini A, Xiao L, Allen PK, Suzuki A, Hayashi Y, Liao Z, Hofstetter W, Crane C, Komaki R, Bhutani MS, Lee JH, Ajani JA, Welsh J. Celiac node failure patterns after definitive chemoradiation for esophageal cancer in the modern era. Int J Radiat Oncol Biol Phys 83(2):e231-9, 2012. e-Pub 2012. PMID: 22436793.
- Hofstetter WL. Lymphadenectomy as a benchmark to surgical quality in esophagectomy: comment on "variation in lymph node examination after esophagectomy for cancer in the United States". Arch Surg 147(6):511-2, 2012. PMID: 22786537.
- Welsh J, Settle SH, Amini A, Xiao L, Suzuki A, Hayashi Y, Hofstetter W, Komaki R, Liao Z, Ajani JA. Failure patterns in patients with esophageal cancer treated with definitive chemoradiation. Cancer 118(10):2632-40, 2012. e-Pub 2011. PMID: 22565611.
- Harvin JA, Lahat G, Correa AM, Lee J, Maru D, Ajani J, Marom EM, Welsh J, Bhutani MS, Walsh G, Roth J, Mehran R, Vaporciyan A, Rice D, Swisher S, Hofstetter W. Neoadjuvant chemoradiotherapy followed by surgery for esophageal adenocarcinoma: significance of microscopically positive circumferential radial margins. J Thorac Cardiovasc Surg 143(2):412-20, 2012. e-Pub 2011. PMID: 22172216.
- Welsh J, Palmer MB, Ajani JA, Liao Z, Swisher SG, Hofstetter WL, Allen PK, Settle SH, Gomez D, Likhacheva A, Cox JD, Komaki R. Esophageal Cancer Dose Escalation using a Simultaneous Integrated Boost Technique. Int J Radiat Oncol Biol Phys 82(1):468-74, 2012. e-Pub 2010. PMID: 21123005.
- Suzuki A, Xiao L, Hayashi Y, Blum MA, Welsh JW, Lin SH, Lee JH, Bhutani MS, Weston B, Maru DM, Rice DC, Swisher SG, Hofstetter WL, Erasmus J, Ajani JA. Nomograms for Prognostication of Outcome in Patients with Esophageal and Gastroesophageal Carcinoma Undergoing Definitive Chemoradiotherapy. Oncology 82(2):108-113, 2012. e-Pub 2012. PMID: 22328056.
- Hofstetter W. "Current and Future Options for Treating Esophageal Cancer: A Paradigm Shift Toward Organ-Sparing Therapies". Tex Heart Inst J 39(Ms. No. THIJ-12-2841):846-7, 2012. PMID: 23304031.
- Taketa T, Correa AM, Suzuki A, Blum MA, Chien P, Lee JH, Welsh J, Lin SH, Maru DM, Erasmus JJ, Bhutani MS, Weston B, Rice DC, Vaporciyan AA, Hofstetter WL, Swisher SG, Ajani JA. Outcome of Trimodallity-Eligible Esophagogastric Cancer Patients Who Declined Surgery after Preoperative Chemoradiation. Oncology 85(5):300-304, 2012. e-Pub 2012. PMID: 22964903.
Invited Articles
- Hofstetter W. Invited commentary. Esophageal Leaks Repaired by Muscle Flaps. Ann Thorac Surg 88(3):973, 2009. PMID: 19699930.
- Leung KK, Maru D, Abraham S, Hofstetter WL, Mehran R, Anandasabapathy S. Optical EMR: confocal endomicroscopy-targeted EMR of focal high-grade dysplasia in Barrett's esophagus. Gastrointest Endosc 69(1):170-2, 2009. e-Pub 2008. PMID: 18582880.
- Rice D, Swisher S, Pisters K, Fossella F, Herbst R, Hofstetter W, Kies M, Komaki R, Lippman S, Mehran R, Roth J, Stewart D, Vaporciyan A, Walsh G, Cox J. Comment on "Treatment of non-small cell lung cancer stage IIIA: ACCP evidence-based clinical practice guidelines (2nd edition)". Chest 134(6):1349; author reply 1350, 2008. PMID: 19059972.
- Martin LW, Hofstetter W, Swisher SG, Roth JA. Management of intrathoracic leaks following esophagectomy. Adv Surg 40:173-190, 2006. PMID: 17163101.
Editorials
- Hofstetter WL. Invited commentary. Ann Thorac Surg 93(5):1681, 2012. PMID: 22541197.
- Bhutani MS, Hofstetter WL. Transesophageal EUS and EUS-FNA for lung cancer. Where do we go from here?. J Clin Gastroenterol 41(7):644-646, 2007. PMID: 17667046.
Abstracts
- Skinner HD, Xu E, Lee JH, Bhutani MS, Weston B, Suzuki A, Hofstetter WL, Komaki R, Ajani JA, Wu X. A validated miRNA expression profile for response to neoadjuvant therapy in esophageal cancer. 2013 ASCO Annual Meeting, 2013.
- Swisher S, Moughan J, Komaki R, Ajani JA, Wu TT, Hofstetter WL, Konski AA, Willett C. Final Results of RTOG 0246: A Phase II Study of Selective Surgical Resection for Locoreginally Advanced Esophageal Cancer Treated with a Paclitaxel Based Chemoradiation Regimen. ASCO 2013 GI Cancer Symposium, 2013.
- Marom EM, Moran CA, Piu P, Correa AM, Kim ES, Komaki R, Erasmus JJ, Hofstetter WL, Rice DC, Swisher SG. Computed Tomography Findings Predicting Invasiveness of Thymoma. 40th Congress of the International Society of Oncology and Biomarkers, October 13-17, 2012; Jerusalem, Israel, 2012.
Book Chapters
- Hofstetter WL. Multimodality Treatment for Potentially Resectable Esophageal Cancer. In: Shackelford’s Surgery of the Alimentary Tract. Eighth Edition. Elsevier, 382-390, 2018.
- Bruzzi J, Marom E, Hofstetter WL, McAleer M. Esophageal Cancer. In: Oncologic Imaging: A Multidisciplinary Approach. Saunders Elsevier, 2010.
- Kim JY, Hofstetter WL. Tumors of the Mediastinum and Chest Wall. In: Surg Clin North Am. 5. Saunders: Philadelphia, 1019-1040, 2010.
- Hofstetter WL. Salvage Esophagectomy for Persistent Disease After Definitive Chemoradiotherapy. In: Difficult Decisions in Thoracic Surgery, 2010.
Letters to the Editor
- Hofstetter WL, Swisher SG, and Ajani JA. The addition of induction chemotherapy to preoperative, concurrent chemoradiotherapy improves tumor response in patients with esophageal adenocarcinoma (Author reply to Correspondence). Cancer 109: 1449, 2007.
- Hofstetter WL, Ly P, Anthone G, Ortega AE, Vukasin P, and Beart RW Jr.. Prevalence and distribution of anorectal misdiagnoses. West J of Med 168: 549, 1998.
Grant & Contract Support
| Title: | Study of MAGE-A3 in Esophageal Adenocarcinoma |
| Funding Source: | GlaxoSmithKline |
| Role: | Principal Investigator |
| Title: | Clinical Study to Evaluate the Coldplay CryoBalloon Full and Swipe Ablation Systems for the Ablation of Human Esophageal Epithelium |
| Funding Source: | C2 Therapeutics |
| Role: | Principal Investigator |
| Title: | Ablation of Lung Lesions Using Microwave Energy (ALLUME) |
| Funding Source: | NeuWave Medical Inc |
| Role: | Principal Investigator |
Patient Reviews
CV information above last modified June 25, 2024