
Ajay Sheshadri, MD, MSCI
Department of Pulmonary Medicine, Division of Internal Medicine
Present Title & Affiliation
Primary Appointment
Associate Professor, Department of Pulmonary Medicine, Division of Internal Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX
Education & Training
Degree-Granting Education
2014 | Washington University School of Medicine, St. Louis, Missouri, US, M.S. in Clinical Investigation |
2007 | University of Texas Southwestern Medical Center, Dallas, Texas, US, MD |
2003 | Rice University, Houston, Texas, US, BA in Biochemistry |
Postgraduate Training
2013-2014 | Postdoctoral Research Fellowship (Mentored Training Program in Clinical Investigation), Mentored Training Program in Clinical Investigation, Washington University School of Medicine, St. Louis, Missouri |
2010-2013 | Fellowship, Pulmonary and Critical Care Medicine, Washington University School of Medicine, St. Louis, Missouri |
2007-2010 | Clinical Residency, Internal Medicine, University of Texas Southwestern Medical Center, St. Louis, Missouri |
Board Certifications
2014 | ABIM, Critical Care Medicine |
2013 | ABIM, Pulmonary Diseases |
2010 | ABIM, Internal Medicine |
Experience & Service
Academic Appointments
Assistant Professor, Department of Pulmonary Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, 2015 - 2021
Instructor, Washington University School of Medicine, St. Louis, MO, 2015 - 2015
Other Appointments/Responsibilities
Staff Physician, John Cochrane Veterans Affairs Medical Center, St. Louis, MO, 2015 - 2015
Institutional Committee Activities
Member, Resource Oversight Committee ( ROC), 2025 - Present
Co-Chair, DoIM Research Education Subcommittee, 2025 - Present
Member, Mid Career Faculty Committee, 2022 - Present
Member, Credentials Committee of the Medical Staff, 2022 - 2025
Member, Data Literacy Advisory Committee, 2022 - 2023
Member, Clinical Research, Division of Internal Medicine Research Committee, 2021 - Present
Member, IOTOX Working Group, 2019 - Present
Member, Faculty Academic Referee Committee, 2017 - 2020
Honors & Awards
2024 | DoIM Research Excellence, MD Anderson Cancer Center |
2023 | Best Research Mentor, Baylor College of Medicine |
2020 | MDA Teaching Excellence Award, McGovern Medical School |
2013 | AsthmaNet Clinical Skills Development Core Scholarship |
2013 | Outstanding Abstract, American Thoracic Society 2013 International Conference |
2005 | Outstanding Poster, Spring Research Symposium, University of Texas Southwestern Medical Center |
2002 | Predoctoral Scholar, Integrative Graduate and Research Traineeship, Rice University |
2001 | Predoctoral Scholar, Summer Medical and Research Training Program, Baylor College of Medicine |
2000 | Louis J. Walsh Scholarship in Engineering, Rice University |
Professional Memberships
Selected Publications
Peer-Reviewed Articles
- Simbaqueba Clavijo, CA, Odaro, OE, Gandhi, A, Koom-Dadzie, K, Musaelyan, A, Dickson, KB, Chua, R, Bhise, VR, Amoateng, MD, Tomy, S, Leal Alviarez, DJ, Phyu, EM, Bogdanich, I, Andersen, C, Sheshadri, A, Palaskas, NL, Halm, J, Manzano, JM. Immunotherapy-Related Adverse Events and Clinical Outcomes in Adult Solid-Tumor Patients Admitted to an Onco-Hospitalist Medicine Service. Cancers 17(3), 2025. e-Pub 2025. PMID: 39941771.
- Altan, M, Li, R, Li, Z, Chen, R, Sheshadri, A, Tran, HT, Little, L, Baguley, J, Sinson, JC, Vokes, N, Gandhi, S, Antonoff, MB, Swisher, SG, Lizee, GA, Reuben, A, Heymach, JV, Zhang, J. High peripheral T cell diversity is associated with lower risk of toxicity and superior response to dual immune checkpoint inhibitor therapy in patients with metastatic NSCLC. Journal for immunotherapy of cancer 12(12), 2024. e-Pub 2024. PMID: 39721752.
- Shojaee, S, Pannu, JK, Yarmus, L, Fantin, A, MacRosty, C, Bassett Jr, R, Debiane, LG, DePew, ZS, Faiz, S, Jimenez, C, Avasarala, SK, Vakil, E, DeMaio, A, Bashoura, L, Keshava, K, Ferguson, T, Adachi, R, Eapen, GA, Ost, D, Bashour, S, Khan, A, Shannon, VR, Sheshadri, A, Casal, RF, Evans, S, Pew, K, Castaldo, N, Balachandran, D, Patruno, V, Lentz, RJ, Pai, C, Maldonado, F, Roller, L, Ma, J, Zaveri, JS, Los, J, Vaquero, L, Ordonez, E, Yermakhanova, G, Akulian, J, Burks, C, Almario, RR, Sauve, M, Pettee, J, Noor, L, Arain, MH, Grosu, HB. Gravity- vs Wall Suction-Driven Large-Volume Thoracentesis. Chest 166(6):1573-1582, 2024. e-Pub 2024. PMID: 39029784.
- Soto-Lanza, F, Glick, L, Chan, C, Zhong, L, Wilson, NR, Faiz, S, Gandhi, S, Naing, A, Heymach, JV, Shannon, VR, Franco Vega, M, Liao, Z, Lin, SH, Palaskas, NL, Wu, J, Shroff, G, Altan, M, Sheshadri, A. Long-Term Clinical, Radiological, and Mortality Outcomes Following Pneumonitis in Nonsmall Cell Lung Cancer Patients Receiving Immune Checkpoint Inhibitors. Clinical Lung Cancer 25(7):624-633.e2, 2024. e-Pub 2024. PMID: 39183094.
- Walder, JR, Faiz, S, Tummala, S, Weathers, S, Palaskas, NL, Buni, M, Sheshadri, A, Bashoura, L. Diaphragmatic Myopathy Associated with Dual Immune Checkpoint Inhibitors in a Patient with Renal Cell Carcinoma. Journal of Immunotherapy and Precision Oncology 7(4):304-307, 2024. e-Pub 2024. PMID: 39553443.
- Desai, A, Subbiah, V, Roy-Chowdhuri, S, Sheshadri, A, Deshmukh, S, Peters, S. Association of Antibody–Drug Conjugate (ADC) Target Expression and Interstitial Lung Disease (ILD) in Non-Small-Cell Lung Cancer (NSCLC). Cancers 16(22), 2024. e-Pub 2024. PMID: 39594708.
- Sharifi, H, Bertini, CD, Alkhunaizi, M, Hernandez, M, Musa, Z, Borges, C, Turk, I, Bashoura, L, Dickey, BF, Cheng, GS, Yanik, G, Galban, CJ, Guo, HH, Godoy, M, Reinhardt, JM, Hoffman, E, Castro, M, Rondon, G, Alousi, AM, Champlin, RE, Shpall, E, Lu, Y, Peterson, S, Datta, K, Nicolls, MR, Hsu, JL, Sheshadri, A. CT strain metrics allow for earlier diagnosis of bronchiolitis obliterans syndrome after hematopoietic cell transplant. Blood Advances 8(19):5156-5165, 2024. e-Pub 2024. PMID: 39163616.
- Shanthikumar, S, Gower, WA, Srinivasan, S, Rayment, J, Robinson, PD, Bracken, J, Stone, A, Das, S, Barochia, A, Charbek, E, Tamae-Kakazu, M, Reardon, EE, Abts, M, Blinman, T, Calvo, C, Cheng, PC, Cole, TS, Cooke, KR, Davies, SM, De, A, Gross, J, Mechinaud, F, Sheshadri, A, Siddaiah, R, Teusink-Cross, A, Towe, CT, Walkup, LL, Yanik, G, Bergeron, A, Casey, A, Deterding, RR, Liptzin, DR, Schultz, KR, Iyer, NP, Goldfarb, S. Detection of Bronchiolitis Obliterans Syndrome after Pediatric Hematopoietic Stem Cell Transplantation An Official American Thoracic Society Clinical Practice Guideline. American journal of respiratory and critical care medicine 210(3):262-280, 2024. e-Pub 2024. PMID: 38889365.
- Corrigan, KL, Xu, T, Sasaki, Y, Lin, R, Chen, AB, Welsh, JW, Lin, SH, Chang, JY, Ning, MS, Gandhi, S, O'Reilly, MS, Gay, CM, Altan, M, Lu, C, Cascone, T, Koutroumpakis, E, Sheshadri, A, Zhang, X, Liao, L, Zhu, XR, Heymach, JV, Nguyen, Q, Liao, Z. Survival outcomes and toxicity of adjuvant immunotherapy after definitive concurrent chemotherapy with proton beam radiation therapy for patients with inoperable locally advanced non-small cell lung carcinoma. Radiotherapy and Oncology 193, 2024. e-Pub 2024. PMID: 38311031.
- Salehjahromi M, Karpinets TV, Sujit SJ, Qayati M, Chen P, Aminu M, Saad MB, Bandyopahyay R, Hong L, Sheshadri A, Lin J, Antonoff MB, Sepesi B, Ostrin EJ, Toumazis L, Hang P, Cheng C, Cascone T, Vokes N, Behrens C, Siewerdsen J, Hazle J, Chang J, Zhang J, Lu Y, B Godoy MC, Chung C, Jaffray D, Wistuba I, Lee J, Vaporciyan A, Gibbons D, Gladish G, Heymach J, Wu CC, Zhang J, Wu J. Synthetic PET from CT improves diagnosis and prognosis for lung cancer: Proof of concept. Cell Reports Medicine, 2024. PMID: 38471502.
- Dickey, JS, Dickey, BF, Alousi, AM, Champlin, RE, Sheshadri, A. Early and rapid development of bronchiolitis obliterans syndrome after allogeneic hematopoietic cell transplantation. Respiratory Medicine Case Reports 49, 2024. e-Pub 2024. PMID: 38745870.
- Shatila, M, Eshaghi, F, Thomas, A, Kuang, AG, Shah, JS, Zhao, B, Naz, S, Sun, M, Fayle, S, Jin, J, Abudayyeh, A, Sheshadri, A, Palaskas, NL, Franco Vega, M, Gaeta, MS, Thomas, AS, Zhang, HC, Wang, Y. Practice Changes in Checkpoint Inhibitor-Induced Immune-Related Adverse Event Management at a Tertiary Care Center. Cancers 16(2), 2024. e-Pub 2024. PMID: 38254858.
- Altan M, Li QZ, Wang Q, Vokes NI, Sheshadri A, Gao J, Zhu C, Tran HT, Gandhi S, Antonoff MB, Swisher S, Wang J, Byers LA, Abdel-Wahab N, Franco-Vega MC, Wang Y, Lee JJ, Zhang J, Heymach JV. Distinct Patterns of Auto Reactive Antibodies Associated with Organ-Specific Immune-Related Adverse Events. Front Immunol 14:1322818, 2023. e-Pub 2023. PMID: 38152395.
- Balachandran DD, Bashoura L, Sheshadri A, Manzullo E, Faiz SA. The Impact of Immunotherapy on Sleep and Circadian Rhythms in Patients with Cancer. Front Oncol 13:1295267, 2023. e-Pub 2023. PMID: 38090501.
- Alexander Franklin, Teny M John, Fareed Khawaja, Ying Jiang, Eduardo Yepez, Jitesh Ahuja, Saadia A Faiz, Lara Bashoura, Ajay Sheshadri, Vickie R Shannon, Diwakar D Balachandran, Kelly McConn. Utility of Bronchoalveolar Lavage for the Diagnosis and Management of COVID-19 in Cancer Patients. Journal of Infectious Disease 228(11):1549-1558, 2023. e-Pub 2023. PMID: 37983000.
- Altan M, Soto F, Zhong LL, Akhmedzhanov FO, Wilson NR, Zarifa A, Albittar AA, Yang V, Lewis J, Rinsurongkawong W, Jack Lee J, Rinsurongkawong V, Zhang J, Gibbons DL, Vaporciyan AA, Jennings K, Khawaja F, Faiz SA, Shannon VR, Shroff G, Godoy MCB, Daver NG, Gandhi S, Mendoza TR, Naing A, Daniel-MacDougall C, Heymach JV, Sheshadri A. Incidence and Risk Factors for Pneumonitis Associated With Checkpoint Inhibitors in Advanced Non-Small Cell Lung Cancer: A Single Center Experience. Oncologist 28(11):e1065-e1074, 2023. e-Pub 2023. PMID: 37156009.
- Wang S, Niroula S, Hoffman A, Khorrami M, Khorrami M, Yuan F, Gasser GN, Choi S, Liu B, Li J, Metersky ML, Vincent M, Crum CP, Boucher RC, Karmouty-Quintana H, Huang HJ, Sheshadri A, Dickey BF, Parekh KR, Engelhardt JF, McKeon FD, Xian W. Inflammatory Activity of Epithelial Stem Cell Variants from Cystic Fibrosis Lung Is Not Resolved by CFTR Modulators. Am J Respir Crit Care Med 208(9):930-943, 2023. e-Pub 2023. PMID: 37695863.
- Ebinama U, Sheshadri A, Anand K, Swaminathan I. Pulmonary Immune-Related Adverse Events of PD1 versus PDL-1 Checkpoint Inhibitors: a retrospective review of pharmacovigilance. J Immunother Precis Oncol 6(4):177-184, 2023. e-Pub 2023. PMID: 38143955.
- Altan M, Soto F, Xu T, Wilson N, Franco-Vega MC, Simbaqueba Clavijo CA, Shannon VR, Faiz SA, Gandhi S, Lin SH, Lopez P, Zhong L, Akhmedzhanov F, Godoy MCB, Shroff GS, Wu J, Khawaja F, Kim ST, Naing A, Heymach JV, Daniel-Macdougall C, Liao Z, Sheshadri A. Pneumonitis After Concurrent Chemoradiation and Immune Checkpoint Inhibition in Patients with Locally Advanced Non-small Cell Lung Cancer. Clin Oncol (R Coll Radiol) 35(10):630-639, 2023. e-Pub 2023. PMID: 37507279.
- Noh S, Bertini C, Mira-Avendano I, Kaous M, Patel B, Faiz SA, Shannon VR, Balachandran DD, Bashoura L, Adachi R, Evans SE, Dickey B, Wu C, Shroff GS, Manzano JG, Granwehr B, Holloway S, Dickson K, Mohammed A, Muthu M, Song H, Team D, Chung C, Wu J, Lee L, Jiang Y, Khawaja F, Sheshadri A. Interstitial lung abnormalities after hospitalization for COVID-19 in patients with cancer: a prospective cohort study. Cancer Med 12(17):17753-17765, 2023. e-Pub 2023. PMID: 37592894.
- Al-Tashi Q, Saad MB, Sheshadri A, Wu CC, Chang JY, Al-Lazikani B, Gibbons C, Vokes NI, Zhang J, Lee JJ, Heymach JV, Jaffray D, Mirjalili S, Wu J. SwarmDeepSurv: Swarm Intelligence Advances Deep Survival Network for Prognostic Radiomics Signatures in Four Solid Cancers. Patterns (N Y) 4(8):100777, 2023. e-Pub 2023. PMID: 37602223.
- Greenhawt M, Dribin TE, Abrams EM, Shaker M, Chu DK, Golden DBK, Akin C, Anagnostou A, ALMuhizi F, Alqurashi W, Arkwright P, Baldwin JL, Banerji A, Bégin P, Ben-Shoshan M, Bernstein J, Bingemann TA, Bindslev-Jensen C, Blumenthal K, Byrne A, Cahill J, Cameron S, Campbell D, Campbell R, Cavender M, Chan ES, Chinthrajah S, Comberiati P, Eastman JJ, Ellis AK, Fleischer DM, Fox A, Frischmeyer-Guerrerio PA, Gagnon R, Garvey LH, Grayson MH, Isabwe GAC, Hartog N, Hendron D, Horner CC, Hourihane JO, Iglesia E, Kan M, Kaplan B, Katelaris CH, Kim H, Kelso JM, Khan DA, Lang D, Ledford D, Levin M, Lieberman JA, Loh R, Mack DP, Mazer B, Mody K, Mosnaim G, Munblit D, Mustafa SS, Nanda A, Nathan R, Oppenheimer J, Otani IM, Park M, Pawankar R, Perrett KP, Peter J, Phillips EJ, Picard M, Pitlick M, Ramsey A, Rasmussen TH, Rathkopf MM, Reddy H, Robertson K, Rodriguez Del Rio P, Sample S, Sheshadri A, Sheik J, Sindher SB, Spergel JM, Stone CA, Stukus D, Tang MLK, Tracy JM, Turner PJ, Vander Leek TK, Wallace DV, Wang J, Wasserman S, Weldon D, Wolfson AR, Worm M, Yacoub MR. Updated guidance regarding the risk of allergic reactions to COVID-19 vaccines and recommended evaluation and management: A GRADE assessment and international consensus approach. J Allergy Clin Immunol 152(2):309-325, 2023. e-Pub 2023. PMID: 37295474.
- Ostrin EJ, Rider NL, Alousi AM, Irajizad E, Li L, Peng Q, Kim ST, Bashoura L, Arain MH, Noor LZ, Patel N, Mehta R, Popat UR, Hosing C, Jenq RR, Rondon G, Hanash SM, Paczesny S, Shpall EJ, Champlin RE, Dickey BF, Sheshadri A. A nasal inflammatory cytokine signature is associated with early graft-versus-host disease of the lung after allogeneic hematopoietic cell transplantation: proof of concept. Immunohorizons 7(6):421-430, 2023. e-Pub 2023. PMID: 37289498.
- Williams LA, Whisenant MS, Mendoza TR, Peek AE, Malveaux D, Griffin DK, Ponce DA, Granwehr BP, Sheshadri A, Hutcheson KA, Ali SM, Peterson SK, Heymach JV, Cleeland CS, Subbiah IM. Measuring symptom burden in patients with cancer during a pandemic: The MD Anderson Symptom Inventory for COVID-19 (MDASI-COVID). J Patient Rep Outcomes 7(1):48, 2023. e-Pub 2023. PMID: 37237077.
- Wang S, Rao W, Hoffman A, Lin J, Li J, Lin T, Liew AA, Vincent M, Mertens TCJ, Karmouty-Quintana H, Crum CP, Metersky ML, Schwartz DA, Davies PJA, Stephan C, Jyothula SSK, Sheshadri A, Suarez EE, Huang HJ, Engelhardt JF, Dickey BF, Parekh KR, McKeon FD, Xian W. Cloning a Pro-fibrotic Stem Cell Variant in Idiopathic Pulmonary Fibrosis. Sci Transl Med 15(693):eabp9528, 2023. e-Pub 2023. PMID: 37099633.
- Al-Tashi Q, Saad MB, Muneer A, Qureshi R, Mirjalili S, Sheshadri A, Le X, Vokes NI, Zhang J, Wu J. Machine Learning Models for the Identification of Prognostic and Predictive Cancer Biomarkers: A Systematic Review. Int J Mol Sci 24(9), 2023. e-Pub 2023. PMID: 37175487.
- Alkhunaizi M, Patel B, Bueno L, Bhan N, Ahmed T, Arain MH, Saliba R, Rondon G, Dickey BF, Bashoura L, Ost DE, Li L, Wang S, Shpall E, Champlin RE, Mehta R, Popat UR, Hosing C, Alousi AM, Sheshadri A. Risk Factors for Bronchiolitis Obliterans Syndrome after Initial Detection of Pulmonary Impairment after Hematopoietic Cell Transplantation. Transplant Cell Ther 29(3):204.e1-204.e7, 2023. e-Pub 2023. PMID: 36503180.
- Aminu M, Daver N, Godoy MCB, Shroff G, Wu C, Torre-Sada LF, Goizueta A, Shannon VR, Faiz SA, Altan M, Garcia-Manero G, Kantarjian H, Ravandi-Kashani F, Kadia T, Konopleva M, DiNardo C, Pierce S, Naing A, Kim ST, Kontoyiannis DP, Khawaja F, Chung C, Wu J, Sheshadri A. Heterogenous lung inflammation CT patterns distinguish pneumonia and immune checkpoint inhibitor pneumonitis and complement blood biomarkers in acute myeloid leukemia: Proof of concept. Front Immunol 14:1249511, 2023. e-Pub 2023. PMID: 37841255.
- Aminu M, Yadav D, Hong L, Young E, Edelkamp P, Saad M, Salehjahromi M, Chen P, Sujit SJ, Chen MM, Sabloff B, Gladish G, de Groot PM, Godoy MCB, Cascone T, Vokes NI, Zhang J, Brock KK, Daver N, Woodman SE, Tawbi HA, Sheshadri A, Lee JJ, Jaffray D, Team D, Wu CC, Chung C, Wu J. Habitat Imaging Biomarkers for Diagnosis and Prognosis in Cancer Patients Infected with COVID-19. Cancers (Basel) 15(1), 2022. e-Pub 2022. PMID: 36612278.
- Xu T, Wu L, Gandhi S, Jing W, Nguyen QN, Chen A, Chang JY, Nurieva R, Sheshadri A, Altan M, Lee PP, Lin SH, Liao Z. Treatment-related pulmonary adverse events induced by chemoradiation and Durvalumab affect survival in locally advanced non-small cell lung cancer. Radiother Oncol 176:149-156, 2022. e-Pub 2022. PMID: 36209942.
- Mendoza TR, Hong DS, Peterson CB, Stephen B, Dumbrava E, Pant S, Tsimberidou AM, Yap TA, Sheshadri A, Altan M, George G, Castillo L, Rodriguez E, Gong J, Subbiah V, Janku F, Fu S, Piha-Paul SA, Ahnert JR, Karp DD, Cleeland C, Meric-Bernstam F, Naing A. Patient-Reported Symptom Burden in Patients with Rare Cancers Receiving Pembrolizumab in a Phase II Clinical Trial. Sci Rep 12(1):14367, 2022. e-Pub 2022. PMID: 35999229.
- Trivedi AP, Hall C, Goss CW, Lew D, Krings JG, McGregor MC, Samant M, Sieren JP, Li H, Schechtman KB, Schirm J, McEleney S, Peterson S, Moore WC, Bleecker ER, Meyers DA, Israel E, Washko GR, Levy BD, Leader JK, Wenzel SE, Fahy JV, Schiebler ML, Fain SB, Jarjour NN, Mauger DT, Reinhardt JM, Newell JD, Hoffman EA, Castro M, Sheshadri A, Program (SARP) NSAR. Quantitative CT Characteristics of Cluster Phenotypes in the Severe Asthma Research Program Cohorts. Radiology 304(2):450-459, 2022. e-Pub 2022. PMID: 35471111.
- Sheshadri A, Goizueta AA, Shannon VR, London D, Garcia-Manero G, Kantarjian HM, Ravandi-Kashani F, Kadia TM, Konopleva MY, DiNardo CD, Pierce S, Zarifa A, Albittar AA, Zhong LL, Akhmedzhanov FO, Arain MH, Alfayez M, Alotaibi A, Altan M, Naing A, Mendoza TR, Godoy MCB, Shroff G, Kim ST, Faiz SA, Kontoyiannis DP, Khawaja F, Jennings K, Daver NG. Pneumonitis after immune checkpoint inhibitor therapies in patients with acute myeloid leukemia: a retrospective cohort study. Cancer 128(14):2736-2745, 2022. e-Pub 2022. PMID: 35452134.
- Sheshadri A, Sacks NC, Healey BE, Raza S, Boerner G, Huang HJ. Lung Function Monitoring After Lung Transplantation and Allogeneic Hematopoietic Stem Cell Transplantation. Clin Ther 44(5):755-765.e6, 2022. e-Pub 2022. PMID: 35513911.
- Sheshadri A, Sacks NC, Huang HJ, Cyr P, Healey B, Boerner G. NIPC after lung transplant. Journal of Medical Economics, 2022. e-Pub 2022.
- Sacks NC, Healey BE, Raza S, Cyr PL, Boerner G, Sheshadri A. The Economic Burden of NIPC and BOS Following allogeneic HSCT in Patients with Commercial Insurance in the United States. Blood Adv 6(5):1566-1576, 2022. e-Pub 2022. PMID: 34807973.
- Sheshadri A, Makhnoon S, Alousi AM, Bashoura L, Andrade R, Miller CJ, Stolar KR, Arain MH, Noor L, Balagani A, Jain A, Blanco D, Ortiz A, Taylor MS, Stenzler A, Mehta R, Popat UR, Hosing C, Ost DE, Champlin RE, Dickey BF, Peterson SK. Home-based spirometry telemonitoring after allogeneic hematopoietic cell transplantation: a mixed methods evaluation of acceptability and usability. JMIR Form Res 6(2):e29393, 2022. e-Pub 2022. PMID: 35129455.
- Trivedi A, Hall C, Goss C, Lew D, Krings J, McGregor M, Samant M, Sieren J, Li H, Schechtman K, Schirm J, McEleney S, Peterson S, Moore W, Bleecker E, Meyers D, Israel E, Washko G, Levy B, Leader J, Wenzel S, Fahy J, Schiebler M, Fain S, Jarjour N, Mauger D, Reinhardt J, Newell J, Hoffman E, Castro M, Sheshadri A. Quantitative Computed Tomographic Characteristics of Cluster Phenotypes in the Severe Asthma Research Program Cohorts. Radiology, 2022. e-Pub 2022.
- Shroff GS, Strange CD, Ahuja J, Altan M, Sheshadri A, Unlu E, Truong MT, Vlahos I. Imaging of Immune Checkpoint Inhibitor Immunotherapy for Non-Small Cell Lung Cancer. Radiographics 42(7):1956-1974, 2022. e-Pub 2022. PMID: 36240075.
- Sheshadri A, Sacks NC, Healey B, Cyr P, Boerner G, Huang HJ. The healthcare resource utilization and costs of chronic lung allograft dysfunction following lung transplantation in patients with commercial insurance in the United States. J Med Econ 25(1):650-659, 2022. e-Pub 2022. PMID: 35502563.
- Patel B, Sheshadri A, Faiz SA. Cavitary Lesions in a Hematopoietic Stem Cell Transplant Patient. Arch Bronconeumol 57(12):768, 2021. e-Pub 2020. PMID: 32576396.
- Wolff D, Radojcic V, Lafyatis R, Cinar R, Rosenstein RK, Cowen EW, Cheng GS, Sheshadri A, Bergeron A, Williams KM, Todd JL, Teshima T, Cuvelier GDE, Holler E, McCurdy SR, Jenq RR, Hanash AM, Jacobsohn D, Santomasso BD, Jain S, Ogawa Y, Steven P, Luo ZK, Dietrich-Ntoukas T, Saban D, Bilic E, Penack O, Griffith LM, Cowden M, Martin PJ, Greinix HT, Sarantopoulos S, Socie G, Blazar BR, Pidala J, Kitko CL, Couriel DR, Cutler C, Schultz KR, Pavletic SZ, Lee SJ, Paczesny S. National Institutes of Health Consensus Development Project on Criteria for Clinical Trials in Chronic Graft-versus-Host Disease: IV. The 2020 Highly morbid forms report. Transplant Cell Ther 27(10):817-835, 2021. e-Pub 2021. PMID: 34217703.
- Krings JG, Goss CW, Lew D, Samant M, McGregor MC, Boomer J, Bacharier LB, Sheshadri A, Hall C, Brownell J, Schechtman KB, Peterson S, McEleney S, Mauger DT, Fahy JV, Fain SB, Denlinger LC, Israel E, Washko G, Hoffman E, Wenzel SE, Castro M, Heart N, Lung, Program Investigators ABISAR. Quantitative CT metrics are associated with longitudinal lung function decline and future asthma exacerbations: results from SARP-3. J Allergy Clin Immunol 148(3):752-762, 2021. e-Pub 2021. PMID: 33577895.
- Turner J, He Q, Baker K, Chung L, Lazarevic-Fogelquist A, Bethune D, Hubbard J, Guerriero M, Sheshadri A, Syrjala KL, Martin PJ, Boeckh M, Lee SJ, Gooley T, Flowers ME, Cheng GS. Home Spirometry Telemonitoring for Early Detection of Bronchiolitis Obliterans Syndrome in Patients with Chronic Graft Versus Host Disease. Transplant Cell Ther 27(7):616.e1-616.e6, 2021. e-Pub 2021. PMID: 33781975.
- Sheshadri A, Keus L, Blanco D, Lei X, Kellner C, Shannon VR, Balachandran DD, Jimenez CA, Bashoura L, Faiz SA. Pulmonary function testing in patients with tracheostomies: feasibility and technical considerations. Lung 199(3):307-310, 2021. e-Pub 2021. PMID: 33779802.
- Evans SE, Jennerich AL, Azar MM, Cao B, Crothers K, Dickson RP, Herold S, Jain S, Madhavan A, Metersky ML, Myers LC, Oren E, Restrepo MI, Semret M, Sheshadri A, Wunderink RG, Dela Cruz CS. Nucleic Acid-based Testing for Noninfluenza Viral Pathogens in Adults with Suspected Community-acquired Pneumonia. An Official American Thoracic Society Clinical Practice Guideline. Am J Respir Crit Care Med 203(9):1070-1087, 2021. e-Pub 2021. PMID: 33929301.
- Sheshadri A, Saliba R, Patel B, Ahmed T, Bueno LC, Arain MH, Mehta RS, Popat UR, Hosing CM, Rondon G, Bashoura L, Dickey BF, Champlin RE, Alousi AM. Azithromycin may increase hematologic relapse rates in matched unrelated donor hematopoietic cell transplant recipients who receive anti-thymocyte globulin, but not in most other recipients. Bone Marrow Transplant 56(3):745-748, 2021. e-Pub 2020. PMID: 33009515.
- Sagar AES, Landaeta MF, Adrianza AM, Aldana GL, Pozo L, Armas-Villalba A, Toquica CC, Larson AJ, Vial MR, Grosu HB, Ost DE, Eapen GA, Sheshadri A, Morice RC, Shannon VR, Bashoura L, Balachandran DD, Almeida FA, Uzbeck MH, Casal RF, Faiz SA, Jimenez CA. Complications following symptom limited thoracentesis using suction. Eur Respir J 56(5), 2020. e-Pub 2020. PMID: 32499336.
- Sheshadri A, Alousi A, Bashoura L, Stolar K, Baghaie S, Arain MH, Noor L, Balagani A, Jain A, Blanco D, Ortiz A, Peterson SK, Langhals R, Taylor M, Stenzler A, Mehta RS, Popat UR, Hosing C, Rondon G, Shen F, Li L, Cheng GS, Ost DE, Champlin RE, Dickey BF. Feasibility and Reliability of Home-based Spirometry Telemonitoring in Allogeneic Hematopoietic Cell Transplant Recipients. Ann Am Thorac Soc 17(10):1329-1333, 2020. e-Pub 2020. PMID: 32614241.
- Mendoza T, Sheshadri A, Altan M, Hess K, George G, Stephen B, Castillo L, Rodriguez E, Gong J, Peterson C, Rodon Ahnert J, Fu S, Piha-Paul SA, Pant S, Dumbrava E, Yap TA, Janku F, Tsimberidou AM, Subbiah V, Karp DD, Zarifa A, McQuinn LM, Cleeland C, Hong DS, Naing A. Evaluating the psychometric properties of the Immunotherapy module of the MD Anderson Symptom Inventory. J Immunother Cancer 8(2), 2020. e-Pub 2020. PMID: 33097611.
- Bailey M, Eapen G, Ost D, Casal RF, Jimenez C, Datar S, Molina S, Bashoura L, Faiz SA, Balachandran DD, Shannon VR, Sheshadri A, Grosu HB. Routine Microbiologic Studies of Pleural Fluid Specimens in Cancer Patients. Am J Med 133(2):240-244, 2020. e-Pub 2020. PMID: 31401163.
- Grosu HB, Lu W, Ost DE, Vial MR, Hernandez M, Ghosh N, Noor L, Hasan AM, Bashoura L, Faiz S, Balachandran D, Casal R, Eapen G, Shannon V, Sheshadri A, Tang X, Rahman N, Wistuba II. Pleural Fluid Cytokine Levels at Baseline and Over Time are Associated With Time to IPC Removal: An Exploratory Study. J Bronchology Interv Pulmonol 27(1):4-13, 2020. e-Pub 2020. PMID: 31373905.
- Grosu H, Lu W, Ost D, Vial M, Hernandez M, Ghosh N, Noor L, Arain M, Bashoura L, Faiz S, Balachandran D, Casal R, Eapen G, Shannon V, Sheshadri A, Tang X, Wistuba I. A Longitudinal Assessment of Pleural Fluid Cytokines in Patients with Malignant Pleural Effusions Treated with an Indwelling Pleural Catheter: Can We Predict Pleurodesis?. J Bronchology Interv Pulmonol 27(1):4-13, 2020. e-Pub 2020. PMID: 31373905.
- Jose R, Dickey B, Sheshadri A. Airway Diseases in Hematologic malignancies. Clinical Pulmonary Medicine, 2020. e-Pub 2020.
- Kim ST, Sheshadri A, Shannon V, Kontoyiannis DP, Kantarjian H, Garcia-Manero G, Ravandi F, Im JS, Boddu P, Bashoura L, Balachandran DD, Evans SE, Faiz S, Ruiz Vazquez W, Divenko M, Mathur R, Tippen SP, Gumbs C, Neelapu SS, Naing A, Wang L, Diab A, Futreal A, Nurieva R, Daver N. Distinct Immunophenotypes of T Cells in Bronchoalveolar Lavage Fluid From Leukemia Patients With Immune Checkpoint Inhibitors-Related Pulmonary Complications. Front Immunol 11:590494, 2020. e-Pub 2020. PMID: 33552049.
- Sheshadri A, Karimipour M, Vakil E, Bashoura L, Godoy M, Arain MH, Evans SE, Dickey BF, Ost DE, Chemaly RF, Faiz SA. Refinement of estimates of mortality risk using the Radiologic Severity Index in hematologic malignancy patients with respiratory syncytial virus infection. Transpl Infect Dis 21(4):e13105, 2019. e-Pub 2019. PMID: 31081570.
- Sheshadri A, Chemaly RF, Alousi AM, Shah PK, Rondon G, Bashoura L, Kmeid J, Azzi J, Blanco DW, Kaous M, Dickey BF, Champlin RE, Shah DP. Pulmonary impairment following respiratory viral infections is associated with high mortality in allogeneic hematopoietic cell transplant recipients. Biol Blood Marrow Transplant 25(4):800-809, 2019. e-Pub 2019. PMID: 30521974.
- Sheshadri A, Godoy M, Erasmus JJ, Gruschkus S, Hasan A, Evans SE, Barreda-Garcia J, Chemaly RF, Dickey B, Ost D. Progression of the Radiologic Severity Index is associated with increased mortality and healthcare resource utilisation in acute leukaemia patients with pneumonia. BMJ Open Respir Res 6(1):e000471, 2019. e-Pub 2019. PMID: 31921429.
- Debiane L, Reitzel R, Rosenblatt J, Gagea M, Chavez MA, Adachi R, Grosu HB, Sheshadri A, Hill LR, Raad I, Ost DE. A Design-Based Stereologic Method to Quantify the Tissue Changes Associated with a Novel Drug-Eluting Tracheobronchial Stent. Respiration 98(1):1-10, 2019. e-Pub 2019. PMID: 30799409.
- Lai K, Shannon VR, Balachandran D, Sheshadri A, Bashoura L, Faiz SA. Role of Infliximab in Immune Check Point Inhibitor Induced Pneumonitis. American Journal of Respiratory and Critical Care Medicine 199, 2019. e-Pub 2019.
- Vakil E, Sheshadri A, Faiz SA, Shah DP, Zhu Y, Li L, Kmeid J, Azzi J, Balagani A, Bashoura L, Ariza-Heredia E, Chemaly RF. Risk factors for mortality after respiratory syncytial virus lower respiratory tract infection in adults with hematologic malignancies. Transpl Infect Dis 20(6):e12994, 2018. e-Pub 2018. PMID: 30195271.
- Patel S, Leavey A, Sheshadri A, Kumar P, Kandikuppa S, Tarsi J, Mukhopadhyay K, Johnson P, Balakrishnan K, Schechtman KB, Castro M, Yadama G, Biswas P. Associations between Household Air Pollution and Reduced Lung Function in Women and Children in Rural Southern India. Journal of Applied Tocicology 38(11):1405-1415, 2018. e-Pub 2018. PMID: 30047157.
- Fujii T, Colen RR, Bilen MA, Hess KR, Hajjar J, Suarez-Almazor ME, Alshawa A, Hong DS, Tsimberidou A, Janku F, Gong J, Stephen B, Subbiah V, Piha-Paul SA, Fu S, Sharma P, Mendoza T, Patel A, Thirumurthi S, Sheshadri A, Meric-Bernstam F, Naing A. Incidence of immune-related adverse events and its association with treatment outcomes: the MD Anderson Cancer Center experience. Invest New Drugs 36(4):638-646, 2018. e-Pub 2018. PMID: 29159766.
- Colen RR, Fujii T, Bilen MA, Kotrotsou A, Abrol S, Hess KR, Hajjar J, Suarez-Almazor ME, Alshawa A, Hong DS, Giniebra-Camejo D, Stephen B, Subbiah V, Sheshadri A, Mendoza T, Fu S, Sharma P, Meric-Bernstam F, Naing A. Radiomics to predict immunotherapy-induced pneumonitis: proof of concept. Invest New Drugs 36(4):601-607, 2018. e-Pub 2018. PMID: 29075985.
- Ontiveros N, Eapen-John D, Osorio N, Song J, Li L, Sheshadri A, Tiang X, Ghosh N, Vaporciyan A, Correa A, Walsh G, Grosu HB, Ost DE. Predicting post-operative lung function following lobectomy: a new method to adjust for inherent selection bias. Respiration 96(5):434-445, 2018. e-Pub 2018. PMID: 30257257.
- Sheshadri A, Shah DP, Godoy M, Erasmus JJ, Song J, Li L, Evans SE, Chemaly RF, Dickey BF, Ost DE. Progression of the Radiologic Severity Index Predicts Mortality in Patients with Parainfluenza Virus-Associated Lower Respiratory Infections. PLoS One 13(5):e0197418, 2018. e-Pub 2018. PMID: 29771962.
- Sheshadri A, Rodriguez A, Chen R, Kozlowski J, Burgdorf D, Koch T, Tarsi J, Schutz R, Wilson B, Schechtman K, Leader JK, Hoffman EA, Castro M, Fain SB, Gierada DS. Effect of Reducing Field of View on Multidetector Quantitative Computed Tomography Parameters of Airway Wall Thickness in Asthma. Journal of Computer Assisted Tomography 39(4):584-90, 2015. e-Pub 2015. PMID: 25938213.
- Thomen RP, Sheshadri A, Quirk JD, Kozlowski J, Ellison HD, Szczesniak RD, Castro M, Woods JC. Regional ventilation changes in severe asthma after bronchial thermoplasty with (3)He MR imaging and CT. Radiology 274(1):250-9, 2015. e-Pub 2015. PMID: 25144646.
- Witt CA, Sheshadri A, Carlstrom L, Tarsi J, Kozlowski J, Wilson B, Gierada DS, Hoffman E, Fain SB, Cook-Granroth J, Sajol G, Sierra O, Giri T, O'Neill M, Zheng J, Schechtman KB, Bacharier LB, Jarjour N, Busse W, Castro M, Program (SARP) NSAR. Longitudinal changes in airway remodeling and air trapping in severe asthma. Academic Radiology 21(8):986-93, 2014. e-Pub 2014. PMID: 25018070.
- Castro M, King TS, Kunselman SJ, Cabana MD, Denlinger L, Holguin F, Kazani SD, Moore WC, Moy J, Sorkness CA, Avila P, Bacharier LB, Bleecker E, Boushey HA, Chmiel J, Fitzpatrick AM, Gentile D, Hundal M, Israel E, Kraft M, Krishnan JA, LaForce C, Lazarus SC, Lemanske R, Lugogo N, Martin RJ, Mauger DT, Naureckas E, Peters SP, Phipatanakul W, Que LG, Sheshadri A, Smith L, Solway J, Sullivan-Vedder L, Sumino K, Wechsler ME, Wenzel S, White SR, Sutherland ER, Heart N, Lung, Institute’s AsthmaNet AB. Effect of vitamin D3 supplementation on asthma treatment failures in adults with symptomatic asthma and lower vitamin D levels: the VIDA randomized clinical trial. Journal of the American Medical Association 311(20):2083-91, 2014. e-Pub 2014. PMID: 24838406.
- Valley T, Sheshadri A, Hoopman T. A young man with empyema: a report of isolated fusobacterial disease. Infect Dis Clin Pract 19(6):e31-e32, 2011. e-Pub 2011.
- Sheshadri A, Rajaram R, Baugh A, Castro M, Correa A, Soto F, Daniel-MacDougall C, Evans S, Dickey B, Vaporciyan A, Ost D. Prediction of pulmonary complications after lobectomy in non-small cell lung cancer using race-neutral and race-specific normative pulmonary function equations. Annals.
- Sheshadri A, Sacks N, Healey B, Cyr P, Boerner G, Huang H. The Economic Burden of Bronchiolitis Obliterans Syndrome Following Lung Transplantation in Patients with Commercial Insurance in the United States. JSHLT.
- Cheng G, Crothers K, Alberti S, Bergeron A, Boeckh M, Chien J, Cilloniz C, Cohen K, Dean N, Dela Cruz C, Dickson R, Greninger A, Hage C, Hohl T, Holland S, Keane J, Metersky M, Tarrand J, Jones B, Miller R, Puel A, Ramirez J, Restropo M, Sheshadri A, Staitieh B, Winthrop K, Wunderink R, Evans S. Immunocompromised host pneumonia definitions and diagnostic criteria. An American Thoracic Society Workshop Report.
Invited Articles
- Sheshadri A, Scott E Evans. Respiratory Syncytial Virus Vaccination in the Adult Pulmonary Patient. ELSEVIER 166(5):963-974, 2024. e-Pub 2024. PMID: 38885895.
- Girish S. Shroff MD, Sheshadri A, Mehmet Altan MD, Mylene T. Truong MD, Lauren T. Erasmus, Ioannis Vlahos MBBS. Drug-induced Lung Disease in the Oncology Patient: From Cytotoxic Agents to Immunotherapy. Clinics in Chest Medicine 45(2):325-337, 2024. PMID: 38816091.
- Sheshadri A, Maanasi Samant MD, James G. Krings MD, MSCI, Daphne Lew PhD, MPH, Charles W. Goss PhD, Tammy Koch RN, Mary Clare McGregor MD, Jonathan Boomer PhD, Chase S. Hall MD, Ken B. Schechtman PhD, Samuel Peterson MS, Serpil Erzurum MD, Zachary DePew MD, Lee E. Morrow MD, D. Kyle Hogarth MD, Richard Tejedor MD, Jennifer Trevor MD, Michael E. Wechsler MD, Afshin Sam MD, Xiaosong Shi MS, Mario Castro MD, MPH. Use of Quantitative CT Imaging to Identify Bronchial Thermoplasty Responders. Chest 165(4):775-784, 2023. e-Pub 2023. PMID: 38123124.
- Azhar M, Abrencillo R, Gandhi S, Altan M, Sheshadri A. Immunotherapy-related pneumonitis and the synergic impact of thoracic radiation and preexisting interstitial lung disease. Curr Opin Pulm Med 29(4):248-255, 2023. e-Pub 2023. PMID: 37170920.
- Bertini CD, Khawaja F, Sheshadri A. Coronavirus Disease-2019 in the Immunocompromised Host. Clin Chest Med 44(2):395-406, 2023. e-Pub 2023. PMID: 37085228.
- )Shroff G, Sheshadri A Altan M, Truong M, Erasmus L, Vlahos I. Drug-Induced Lung Disease in the Oncology Patient: from cytotoxic agents to immunotherapy. Clinics in Thoracic Imaging 2023, 2023. e-Pub 2023.
- Jain A, Shannon V, Sheshadri A. Pneumonitis after precision oncology therapies: a concise review. Journal of Immunotherapy and Precision Oncology 1(1):26-37, 2018. e-Pub 2018.
- Sheshadri A, McKenzie M, Castro M. Critical Review of Bronchial Thermoplasty: Where Should It Fit in Asthma Therapy?. Curr Allergy and Asthma Rep 14(11):470, 2014. e-Pub 2014. PMID: 25189294.
- Sheshadri A, Castro M, Chen A. Bronchial thermoplasty: a novel therapy for severe asthma. Clin Chest Med 34(3):437-444, 2013. e-Pub 2013. PMID: 23993815.
- Sheshadri A, Chang Li, Saadia A. Faiz, Megan B. Osborn, MD MHPE, Ajay Sheshadri, Monica Wattana. Immune Checkpoint Inhibitor Associated Pneumonitis: A Narrative Review.
Other Articles
- Sheshadri A White-202408-846OC.R2 - Race-Specific vs Race-Neutral Pulmonary Function Predicted Values in Operable Lung Cancer Patients. Annals of the American Thoracic Society.
- Bertini, CD, Khawaja, F, Sheshadri, A Coronavirus Disease-2019 in the Immunocompromised Host. Rheumatic Disease Clinics of North America 51(1):123-138, 2025. PMID: 39550101.
- Sheshadri A, ma531@stanford.edu, Sharifi, Husham, Chen, Guang-Shing Restrictive Ventilatory Defects Following Hematopoietic Stem Cell Transplant Are Associated With Increased Mortality Transplantation and Cellular Therapy. ASTCT.
- Chan, KL, Faiz, S, Altan, M, Sheshadri, A Updates in Drug-Related Pneumonitis Due to Targeted Oncologic Therapies. Journal of Immunotherapy and Precision Oncology 7(4):272-282, 2024. PMID: 39524467.
- Sheshadri A, Aakash Desai, Vivek Subbiah, Sinchita Roy-Chowdhuri, Sameer Deshmukh, Solange Peters Association of Antibody Drug Conjugates (ADC) Target Expression and Interstitial Lung Disease (ILD) in Non-Small Cell Lung Cancer (NSCLC):. MDPI.
- Auld, SC, Sheshadri, A, Alexander-Brett, J, Aschner, Y, Barczak, AK, Basil, MC, Cohen, K, Dela Cruz, CS, McGroder, C, Restrepo, MI, Ridge, KM, Schnapp, LM, Traber, K, Wunderink, RG, Zhang, D, Ziady, A, Attia, EF, Carter, J, Chalmers, JD, Crothers, K, Feldman, C, Jones, BE, Kaminski, N, Keane, J, Lewinsohn, DM, Metersky, ML, Mizgerd, JP, Morris, A, Ramirez, JA, Samarasinghe, AE, Staitieh, B, Stek, C, Sun, J, Evans, S Postinfectious Pulmonary Complications. Annals of the American Thoracic Society 21(9):1219-1237, 2024. PMID: 39051991.
- Sheshadri A, Bashoura Lara, Saddia Faiz, Walder Jeremy Diaphragmatic Myopathy Associated with Dual Immune Checkpoint Inhibitors in a Patient with Renal Cell Carcinoma. Journal of Immunotherapy and Precision Oncology.
- Sheshadri A, Sujit SJ, Aminu M, Karpinets TV, Chen P, Saad MB, Salehjahromi M, Boom JD, Qayati M, George JM, Allen H, Antonoff MB, Hong L, Hu X, Heeke S, Tran HT, Le X, Elamin YY, Altan M, Vokes NI, Lin J, Zhang J, Lu Y, Behrens C, Godoy MCB, Wu CC, Chang JY, Chung C, Jaffray DA, Wistuba II, Lee JJ, Vaporciyan AA, Gibbons DL, Heymach J, Zhang J, Cascone T, Wu J Enhancing NSCLC recurrence prediction with PET/CT habitat imaging, ctDNA, and integrative radiogenomics-blood insights. Nat Commun 15(1):3152, 2024. PMID: 38605064.
- Bertini, CD, Khawaja, F, Sheshadri, A Coronavirus Disease-2019 in the Immunocompromised Host. Infectious Disease Clinics of North America 38(1):213-228, 2024. PMID: 38280765.
- Keam, S, Turner, N, Grande Kugeratski, F, Rico, R, Colunga-Minutti, JG, Poojary, R, Alekseev, S, Patel, A, Li, YJ, Sheshadri, A, Loghin, ME, Woodman, K, Aaroe, AE, Hamidi, S, Iyer, PC, Palaskas, NL, Wang, Y, Nurieva, R Toxicity in the era of immune checkpoint inhibitor therapy. Frontiers in immunology 15, 2024. PMID: 39247203.
- Soto F, Torre-Sada LF, Mott FE, Kim ST, Nurieva R, Shannon VR, Faiz SA, Casal RF, Altan M, Lin J, Sheshadri A Sarcoidosis and Airway Disease After Immune Checkpoint Inhibitor Therapy: Case Study and Review of the Literature. J Immunother Precis Oncol 6(2):111-116, 2023. PMID: 37214206.
- Balagani A, Arain M, Sheshadri A Case report: Bronchiolitis obliterans after combination immunotherapy with pembrolizumab and ipilimumab. J Immunother Precis Oncol 1(1):49-52, 2018.
- Sheshadri A High peripheral T cell diversity is associated with lower risk of toxicity and superior response to dual immune checkpoint inhibitor therapy in patients with metastatic NSCLC.
Editorials
- Sheshadri A, Huang HJ, Bashoura L, Alousi AM, Alkhunaizi M, Sharifi H, Hsu JL. Graft-versus-host disease may cause pulmonary restriction, but not all restriction is graft-versus-host disease. Blood Adv 6(17):4984-4986, 2022. PMID: 35793452.
- Sheshadri A. Quantitative lung imaging in hematopoietic cell transplant recipients: a window into the physiology of bronchiolitis obliterans. Chest 158(3):852-853, 2020. PMID: 32892879.
- Sumino K, Sheshadri A, Castro M. Calcium channel blocker reduces airway remodeling. Or does it?. Am J Respir Crit Care Med 191(8):876-83, 2015. PMID: 25876196.
- Sheshadri A, Hoffman EA, Castro M. Can computed tomography help us identify asthmatic phenotypes?. J Allergy Clin Immunol 133(3):739-40, 2014. PMID: 24472625.
Abstracts
- Sheshadri A, Carlos Ignacio Rodríguez Reyna, Erick Torres Luna, Saadia Faiz MD, Lara Bashoura MD, Nathan Box MD. Nocardia empyema in an immunocompromised host: A case report. ELSEVIER, 2025. e-Pub 2025.
- Sheshadri A, C.Mollings Puentes, Y.M Sasaki, S. Koutroumpakis, A. Deswal, Q.N. Nguyen, D.Qian, J.Bronk, S. Gandhi, 1 T Cascone, M. Altan, A.B. Chen, Z. Liao, T. Xu, X. Le. CCI as a Predictive Tool of Treatment Tolerance and Outcomes in Elderly NSCLC Patients Treated with Concurrent Proton or Photon Chemoradiation followed by Immunotherapy. e-Pub 2025.
- Sheshadri A, Muhammad Aminu, Lingzhi Hong, Natalie Vokes, Stephanie T Schmidt, Maliazurina Saad, Bo Zhu, Xiuning Le, Cascone Tina, Bo Wang, David Jaffray, Andy Futreal, J Jack Lee, Lauren A Byers, Don Gibbons, John Heymach, Ken Chen, Chao Cheng, Jianjun Zhang, Jia Wu. Joint multi-omics discriminant analysis with consistent representation learning using PANDA. Research Square, 2024. PMID: 38798352.
- Sheshadri A, Ravi Rajaram, Aaron Baugh, Mario Castro, Arlene M Correa, Felipe Soto, Carrie R Daniel, Liang Li, Scott E Evans, Burton F Dickey, Ara A Vaporciyan, David E Ost. Association of Preoperative Lung Function with Complications after Lobectomy Using Race-Neutral and Race-Specific Normative Equations. Annals of the American Thoracic Society 21(1):38-46, 2024. e-Pub 2023. PMID: 37796618.
- Sheshadri A, Sung-Yeon Cho, Sebastian Wurster, Takahiro Matsuo, Dimitrios P. Kontoyiannis. Cellular Composition of Bronchoalveolar Lavage Fluid in Patients with Hematologic Malig-nancies and Invasive Pulmonary Aspergillosis: Significant Associations with Peripheral Blood Cell Counts. e-Pub 2024.
- Minshall ME, Kemp DR, Hofstetter E, Boerner G, McGrain J, Siddiqui SJ, Levine DJ, Sheshadri A. The Comparative Humanistic Burden of Bronchiolitis Obliterans Syndrome (BOS) on Patients Undergoing Lung Transplant (LTX) or Allogeneic Hematopoietic Stem Cell Transplantation (allo-HSCT) in the United States. American Journal of Respiratory and Critical Care Medicine:207:A4854, 2023. e-Pub 2023.
- Ebinama U, Sheshadri A, Ahmed S, Lee HJ, Liu M, Iyer SP. Risk of Pneumonitis with Immune Checkpoint Inhibitors in Hodgkin’s Lymphoma and Other Hematologic Malignancies: A Retrospective Review from Pharmacovigilance. American Society of Hematology, 2022. e-Pub 2022.
- Altan M, Sheshadri A. Auto reactive antibodies as predictive markers for immune checkpoint induced pneumonitis, 2022. e-Pub 2022.
- Alkhunaizi MA, Saliba R, Patel B, Arain M, Mehta R, Popat U, Hosing C, Rondon G, Bashoura L, Bhan N, Dickey B, Champlin R, Alousi A, Sheshadri A. Restrictive Lung Impairment After Hematopoietic Stem Cell Transplant: Etiology and Impact. American Thoracic Society 2022, 2022. e-Pub 2022.
- Mendoza TR, Hong D, Naing A, Hess KR, Sheshadri A, Altan M, Stephen BA, Cleeland C. Evaluating the psychometric properties of the immunotherapy module of the MD Anderson Symptom Inventory (MDASI-Immunotherapy). Joint Statistical Meetings 2019, 2019. e-Pub 2019.
- Sheshadri A, Godoy M, Erasmus J, Arain M, Evans S, Barreda-Garcia J, Chemaly R, Dickey B, Ost D. Progression of the Radiologic Severity Index is associated with increased mortality in patients with acute leukemia who develop pneumonia after induction chemotherapy. American Journal of Respiratory and Critical Care Medicine 199, 2019. e-Pub 2019.
- Sang K, Shannon V, Sheshadri A, Kantarjian H, Garcia-Manero G, Ravandi F, Naing A, Sharma P, Im J, Ruiz Vasquez W, Diab A, Kontoyiannis D, Futreal A, Daver N. Immunophenotypic Analysis of T Cells from Leukemia Patients with Immune Checkpoint Inhibitor-Associated Respiratory Complications. American College of Rheumatology, 2018. e-Pub 2018.
- Sood S, Sajol G, Goss C, Sheshadri A, Comhair A, Erzurum S, Hall C, Weaver R, Schutz R, Kozlowski J, Castro M. Longitudinal evaluation of airway remodeling in asthma over time by airway biopsy. American Journal of Respiratory and Critical Care Medicine 197, 2018. e-Pub 2018.
- Sheshadri A, Balagani A, Alousi A, Bashoura L, Stolar K, Arain M, Noor L, Blanco D, Ortiz A, Goodwin N, Chen M, Li L, Hess K, Chemaly R, Ost D, Peterson S, Champlin R, Dickey B. Feasibility and Validity of a Home-based Spirometry Program after Hematopoietic Stem Cell Transplantation for the Early Detection of Pulmonary Impairment. American Journal of Respiratory and Critical Care Medicine 197, 2018. e-Pub 2018.
- Kim S, Shannon V, Sheshadri A, Kantarjian H, Garcia-Manero G, Im J, Ravandi F, Naing A, Sharma P, Kontoyiannis D, Futreal A, Daver N. Th1/17 Cells are Expanded in Bronchial Alveolar Lavage (BAL) Fluid from Leukemia Patients with Checkpoint Inhibitor-Induced Pneumonitis. Blood 130:3588, 2017. e-Pub 2017.
- Trivedi A, Sheshadri A, Goss C, Sieren J, Escher M, Schutz R, Li H, Schechtman K, Moore W, Bleecker E, Hoffman E, Castro M. The Use Of CT To Characterize Cluster Phenotypes In The Severe Asthma Research Program. American Journal of Respiratory and Critical Care Medicine 195, 2017. e-Pub 2017.
- Hall C, Trivedi AP, Sheshadri A, Boomer J, Yin Declue H, Sajol G, Goss C, Kozlowski J, Gierada D, Sieren JP, Escher M, Schutz R, Li H, Schechtman KB, Moore WC, Bleecker ER, Hofman EA, Castro M, Program (SARP) OBOTNSAR. Airway Remodeling Measured by Targeted Biopsies in Severe Asthma. American Journal of Respiratory and Critical Care Medicine 195, 2017. e-Pub 2017.
- Sheshadri A, Kmeid J, Azzi J, Kaous M, Blanco D, Bashoura L, Rondon G, Alousi A, Dickey B, Chemaly R, Shah D. Pulmonary Function Decline after Respiratory Viral Infection Predicts Mortality after Hematopoetic Cell Transplantation. American Thoracic Society, 2017. e-Pub 2017.
- Sheshadri A, Jiao J, Carlstrom L, Sieren JP, Escher M, Sajol G, Yin-Declue H, Tarsi J, Schutz R, Wilson B, Li H, Schechtman K, Moore WC, Bleecker ER, Hoffman EA, Castro M. MDCT Characteristics of Pre-Specified Asthmatic Cluster Phenotypes in the Severe Asthma Research Program. American Journal of Respiratory and Critical Care Medicine, 2015. e-Pub 2015.
- Sarikonda K, Sheshadri A, Koch T, Kozlowski J, Wilson B, Schechtman K, Chen A, Castro M. Predictors of Bronchial Thermoplasty Response in Patients with Severe Refractory Asthma. American Journal of Respiratory and Critical Care Medicine, 2014. e-Pub 2014.
- Sheshadri A, Rodriguez A, Chen R, Kozlowski J, Burgdorf D, Koch T, Tarsi J, Sajol G, Yin-Declue H, Wilson B, Schechtman K, Castro M, Fain S, Gierada D. Reducing Field of View in Multi-Detector Quantitative Computed Tomography Improves Accuracy of Measures of Airway Wall Remodeling. American Journal of Respiratory and Critical Care Medicine, 2014. e-Pub 2014.
- Sheshadri A, Thomen R, Kozlowski J, Gierada D, Tarsi J, Koch T, Burgdorf D, Sajol G, Yin-DeClue H, Wilson B, Schechtman K, Quirk J, Castro M, Woods J. Ventilation defects with hyperpolarized helium MRI in severe asthma before and after bronchial thermoplasty. American Journal of Respiratory and Critical Care Medicine 187, 2013. e-Pub 2013.
- Thomen R, Sheshadri A, Kozlowski J, Quirk J, Chang Y, Castro M, Woods J. Ventilation Quantification Bronchopulmonary Segments in Severe Asthma Using 3He MRI and High Resolution CT. American Journal of Respiratory and Critical Care Medicine 187, 2013. e-Pub 2013.
- Sheshadri A, Witt C, Gierada D, Kozlowski J, Hoffman EA, Cook-Granroth J, Fain SB, Busse WW, Zheng J, Wilson B, Schechtman K, Castro M. Predictors of Airway Remodeling and Decline in Lung Function in Severe Asthma. American Journal of Respiratory and Critical Care Medicine 185, 2012. e-Pub 2012.
- Sheshadri A, Mineo C, Yuhanna IS, Shaul PW. Inhibition of HDL-mediated eNOSactivation by the SR-BI inhibitor glyburide, 2005. e-Pub 2005.
- Sheshadri A. The Use Of Cardiopulmonary Exercise Testing In The Pre-operative Evaluation Of Lobectomy Patients Within The Veterans Health Administration.
- Lanza F, Wilson N, Zhong L, Franco-Vega M, Simbaqueba C, Khawaja F, Shannon V, Liao Z, Ghandi S, Xu T, Sheshadri A, Altan M. ESMO PACIFIC #5607 Pneumonitis after chemoradiation and consolidation durvalumab for locally advanced non-small cell lung cancer: a single center experience.
- Gordon N, Kleinerman ES, Sheshadri A, Blanco DW, Yedururi S, Morani A, Gill JB, Harrison DJ, Herzog CE, Livingston JA, Benjamin RS, Mireles ME, Kawedia J, Daw NC. A Phase I Trial of Aerosol Gemcitabine for the Treatment of Patients with Solid Tumors and Lung Metastases. Journal of Clinical Oncology 38(15).
- Glick L, Iliescu C, Koutroumpakis E, Altan M, Deswal A, Sheshadri A, Palaskas N. Factors associated with One Year Survival among Patients who Develop Immune Checkpoint Inhibitor Myocarditis. CHEST.
- Xian W, Mckeon F, Huang H, Safdar Z, Vincent M, Boucher R, Dickey B, Engelhardt J, Crum C, Karmouty-Quintana H, Sheshadri A, Parekh K, Schwartz D, Metersky M, Wechsler M. The Spectrum And Pathogenicity Of Clonogenic Basal Cells In Lung Disease. ATS 2024.
- Sharifi H, Bertini CD, Alkhunaizi MA, Hernandez M, Turk I, Bashoura L, Dickey B, Cheng G, Yanik G, Galban C, Godoy M, Guo HH, Reinhardt J, Hoffman E, Castro M, Alousi AM, Champlin RE, Shpall EJ, Rondon, G, Peterson S, Datta K, McEleney S, Hsu JL, Sheshadri A. Distinguishing Early Bronchiolitis Syndrome After Hematopoietic Cell Transplantation Using Novel Lung Strain Metrics from Chest CT Scans. CHEST.
- George GC, Mendoza TR, Naing A, Hong D, Cleeland C, Sheshadri A, Hess KR, Altan M, Stephen BA, Castillo L, Rodriguez E, Yap TA, Janku F, Fu S, Pant S, Subbiah V, Piha-Paul SA, Karp DD, Meric-Bernstam F. Patient-Reported Symptom Burden in Patients with Rare Cancers Receiving Pembrolizumab in a Phase II Clinical Trial.
- Sheshadri A, Carson Tyler Moss, Joe L. Hsu, Mayur Ramesh, Gail M. Gauvreau, Jane Tumer, MyLinh Duong, Rick Nettles, Jason Chien, Ella Neqrou, Fafa Boateng, Dimitri Talantov, Guang-Shing Cheng. The burden of community-acquired respiratory viral infections in high-risk immunocompromised patients post the COVID-19 pandemic.
- Glick L, Soto F, Wilson NR, Zhong LL, Akhmedzanov FO, Xu F, Franco-Vega MC, Clavijo S, Shannon VR, Faiz SA, Gandhi S, Naing A, Heymach JV, Palaskas N, Altan M, Sheshadri A. Factors Associated with One Year Survival among Patients with Non-Small Cell Lung Cancer who Develop Immune Checkpoint Inhibitor Pneumonitis. CHEST.
- Sheshadri A. Bronchiolitis Obliterans Syndrome after Lung Transplantation: Economic Burden by CLAD Stage. International Society for Heart and Lung Transplantation.
- Sheshadri A, Husham Sharifi, Zayan Musa, Carson Tyler Moss, Alex Bell, Christian O’Donnell, Carlos Hernandez Borges, Efthymia Iliana Matthaiou, Laura Johnston, Craig Galban, Gregory Yanik, Guang-Shing Cheng, Joe L. Hsu. STOP BOS abstract for ATS 2025.
Book Chapters
- Farooq S, Faiz S, Shannon V, Altan M, Sheshadri A. Infliximab for the treatment of steroid-dependent immune checkpoint inhibitor pneumonitis. In: Challenging Cases in Immunotherapy Related Organ Toxicities. Springer, 2024.
- Farooq S, Faiz S, Shannon V, Altan M, Sheshadri A. In: Challenging Cases in Immunotherapy Related Organ Toxicities. Springer, 2024.
- Farooq S, Faiz S, Shannon V, Altan M, Sheshadri A. In: Challenging Cases in Immunotherapy Related Organ Toxicities. Springer, 2024.
- Alkhunaizi, M, José, RJ, Sheshadri, A. Pretransplant Pulmonary Evaluation, 63-79, 2023.
- Mehta, RS, Sheshadri, A, Alousi, AM. An Overview of Graft-Versus-Host Disease, 17-44, 2023.
- )Bhandari B, Sheshadri A, Evans S. Respiratory infections in cancer patients. In: Principles and Practices of Cancer Infectious Disease. Springer, 2023.
- Verma, D, Faiz, S, Shannon, VR, Sheshadri, A, Altan, M. Pulmonology (Lung), 275-299, 2022.
- Altan M, Zhong L, Shannon VR, Sheshadri A. Pulmonary Toxicities of Immunotherapy. In: Immunotherapy. 4th. Springer, 357-375, 2021.
- Zhong L, Altan M, Shannon VR, Sheshadri A. Immune-related Adverse Events: Pneumonitis. In: Adv Exp Med Biol, 255-269, 2020.
- Aslam W, Sheshadri A, Lamb C. Chapter 12: Bronchial Thermoplasty. In: Practical Guide to Interventional Pulmonology. 1. Elsevier, 2020.
- Jain A, Shannon VR, Sheshadri A. Immune-related Adverse Events: Pneumonitis. In: Adv Exp Med Biol. 2nd, 131-149, 2018.
- Sarikonda K, Sheshadri A, Castro M. Asthma. In: The Washington Manual of Outpatient Medicine. 2nd. Lippincott, Williams & Wilkins, 2015.
- Sheshadri A, Castro M. Asthma. In: The Washington Manual of Medical Therapeutics. 34th ed. Lippincott, Williams & Wilkins, 2013.
- Atkinson J, Senior R, Sheshadri A, Castro M. Obstructive Lung Disease. In: The Washington Manual of Medical Therapeutics. 34th ed. Lippincott, Williams & Wilkins, 2013.
- Verma D, Faiz SA, Shannon VR, Altan M, Sheshadri A. Pulmonary toxicities after immune checkpoint inhibitor therapies. In: Managing Immunotherapy Related Organ Toxicities: A practical guide. Springer.
- S Farooq, SA Faiz, VR Shannon, Sheshadri A. Pneumonitis and COVID-19 Pneumonia Post Immune Checkpoint Inhibitor Therapy. In: Challenging Cases in Immunotherapy Related Organ Toxicities. SPRINGER NATURE.
- S Farooq, SA Faiz, VR Shannon, Sheshadri A. Immune Checkpoint Inhibitor Associated Pneumonitis in a Patient with Interstitial Lung Abnormalities. In: Challenging Cases in Immunotherapy Related Organ Toxicities. SPRINGER NATURE.
- Mir M, Soto F, Amezcua Gomez PA, Del Rio Arroyo R, Gan Q, Stewart J, Adachi R, Balachandran D, Bashoura L, Casal RF, Dickey DF, Eapen G, Evans S, Grosu H, Jimenez C, Lin J, Ost DE, Sabath BF, Shannon VR, Naing A, Wu J, Suresh K, Altan M, Faiz S, Sheshadri A. Bronchoalveolar lavage (BAL) lymphocytosis as a predictive marker of Immune checkpoint inhibitor (ICI) Pneumonitis – a retrospective analysis. In: Chest.
- S Farooq, SA Faiz, VR Shannon, Sheshadri A. Immune Checkpoint Inhibitor Therapy Induced Relapsing Pneumonitis. In: Challenging Cases in Immunotherapy Related Organ Toxicities. SPRINGER NATURE.
- Shannon V, Eapen G, Jimenez C, Grosu H, Morice RC, Bashoura L, Sheshadri A, Evans S, Adachi R, Kroll M, Faiz S, Balachandran D, Pravinkumar S, Dickey B. Respiratory Complication. In: Cancer Medicine. 10.
Selected Presentations & Talks
Local Presentations
- 2024. Immune Checkpoint Inhibitor Pneumonitis: New Insights, New Directions. Invited. Frontiers in Critical Care Multidisciplinary Research Sessions. Houston, Texas, US.
- Understanding the pathobiology of ICI pneumonitis. 2025 ID Grand Rounds. Houston, TX, US.
Regional Presentations
- 2024. Bronchiolitis Obliterans after Hematopoietic Cell Transplantation. Invited. MRI BOS meeting. Charlottesville, Virginia, US.
National Presentations
- 2025. Pulmonary Toxicities Associated with Immune Checkpoint Inhibitors and CAR-T. ATS Pediatric Assembly Pulmonary Complication in Childhood Cancer Webinar. New York, NY, Texas, US.
- 2024. ICI Pneumonitis: Second Line Treatment and Future Directions. Invited. 2024 MSK Pulmo-Oncology Symposium. New York, NY, Texas, US.
Formal Peers
- 2023. Launching a Hyperpolarized 129Xe Program. Invited. Launching a Hyperpolarized 129Xe Program. Miami, FL, US.
- 2021. Pneumonitis after Immunotherapy in Non-Small Cell Lung Cancer: Navigating Scylla and Charybdis. Invited. Pneumonitis after Immunotherapy in Non-Small Cell Lung Cancer: Navigating Scylla and Charybdis, US.
- 2019. Immunotherapy for treatment of Non-Small Cell Lung Cancer. Invited. Immunotherapy for treatment of Non-Small Cell Lung Cancer. Houston, TX, US.
- 2019. A Roadmap to Obliterating Bronchiolitis after Hematopoietic Cell Transplantation. Invited. A Roadmap to Obliterating Bronchiolitis after Hematopoietic Cell Transplantation. Houston, TX, US.
- 2019. A Roadmap to Obliterating Bronchiolitis after Hematopoietic Cell Transplantation. Invited. A Roadmap to Obliterating Bronchiolitis after Hematopoietic Cell Transplantation. Kansas City, KS, US.
- 2019. Primer on PFTs & Bronchilitis Obliterans after Hematopoeitic Cell Transplantation. Invited. Primer on PFTs & Bronchilitis Obliterans after Hematopoeitic Cell Transplantation. Houston, TX, US.
- 2019. Bronchiolitis Obliterans Syndrome after Hematopoietic Cell Transplantation. Invited. Bronchiolitis Obliterans Syndrome after Hematopoietic Cell Transplantation. Houston, TX, US.
- 2019. Quantitative Imaging of Pneumonia and Bronchiolitis. Invited. Quantitative Imaging of Pneumonia and Bronchiolitis. Grand Rapids, IA, US.
- 2018. Mentorship. Invited. Mentorship. Houston, TX, US.
- 2017. Mentorship. Invited. Mentorship. Houston, TX, US.
- 2016. Severe Asthma: Phenotypes and New Therapies. Invited. Severe Asthma: Phenotypes and New Therapies. Houston, TX, US.
Grant & Contract Support
Date: | 2023 - Present |
Title: | University of Michigan (PRM BoS) |
Funding Source: | NIH/NCI |
Role: | Co-PI |
Date: | 2023 - Present |
Title: | University of Kansas (ALA XeMRI) |
Funding Source: | NIH/NCI |
Role: | Co-PI |
Date: | 2021 - 2026 |
Title: | Longitudinal Impact of Respiratory Viruses and Lung Infections on Bronchiolitis Obliterans Syndrome in Allogeneic Hematopoietic Cell Transplant Recipients |
Funding Source: | NIH/NHLBI |
Role: | Co-I |
Date: | 2020 - 2024 |
Title: | Predictive biomarkers for pneumonitis after chemoradiotherapy and immunotherapy |
Funding Source: | Gateway for Cancer Research |
Role: | Co-PI |
ID: | G-20-400 |
Date: | 2019 - 2020 |
Title: | Mark-III 129Xe Polarizer System |
Funding Source: | NIH |
Role: | Scientific Advisor & Major User |
ID: | PAR-18-600 |
Date: | 2016 - 2022 |
Title: | Predictors of Response in Bronchiolitis Obliterans after Hematopoietic Transplantation |
Funding Source: | NIH/NCI |
Role: | PI |
ID: | K23-AI117024-01 |
Date: | 2012 - 2014 |
Title: | Washington University Institute of Clinical and Translational Sciences |
Funding Source: | NIH/NCATS |
Role: | Research Fellow |
ID: | UL1 TR000448 |
Date: | 2012 - 2014 |
Title: | Principles in Pulmonary Training Grant |
Funding Source: | NIH/NHLBI |
Role: | Research Fellow |
ID: | T32HL007317-34 |
Title: | Parametric Response Mapping (PRM) for the detection of chronic lung injury in hematopoietic cell transplant recipients |
Funding Source: | NIH/NHLBI |
Role: | Co-I |
Patient Reviews
CV information above last modified April 10, 2025