Alberto Diaz De Leon, M.D.
Department of Abdominal Imaging, Division of Diagnostic Imaging
Present Title & Affiliation
Primary Appointment
Director of MRI, Department of Abdominal Imaging, Division of Diagnostic Imaging, The University of Texas MD Anderson Cancer Center, Houston, Texas
Associate Professor, Department of Abdominal Imaging, Division of Diagnostic Imaging, The University of Texas MD Anderson Cancer Center, Houston, TX
Education & Training
Degree-Granting Education
| 2010 | The University of Texas Southwestern Medical Center, Dallas, Texas, US, Doctor of Medicine |
| 2005 | Texas A&M University, College Station, Texas, US, Molecular and Cell Biology, Bachelor of Science |
Postgraduate Training
| 2015-2016 | Fellow, Magnetic Resonance Imaging, The University of Texas Southwestern School, Dallas, Texas |
| 2010-2015 | Resident, Radiology, The University of Texas Southwestern Medical Center, Dallas, Texas |
Experience & Service
Academic Appointments
Assistant Professor, The University of Texas Southwestern Medical School, Dallas, Texas, 2016 - 2022
Assistant Instructor, The University of Texas Southwestern Medical School, Dallas, Texas, 2015 - 2016
Honors & Awards
| 2010 - Present | Doris Duke Physician Scientist Research Fellowship, Doris Duke Foundation |
Selected Publications
Peer-Reviewed Articles
- Recchimuzzi DZ, Diaz de Leon A, Pedrosa I, Travalini D, Latin H, Goldberg K, Meng X, Begovic J, Rayan J, Roehrborn CG, Rofsky NM, Costa DN. Direct MRI-guided In-Bore Targeted Biopsy of the Prostate: A Step-by-Step How To and Lessons Learned. Radiographics 44(2):e230142, 2024. e-Pub 2024. PMID: 38175803.
- Costa DN, Meng X, Tverye A, Bagrodia A, Recchimuzzi DZ, Xi Y, Arraj P, Shah RB, Subramanian N, Diaz de Leon A, Roehrborn CG, Rofsky NM, Chen H, Pedrosa I. Preoperative multiparametric prostate magnetic resonance imaging structured report informs risk for positive apical surgical margins during radical prostatectomy. J Comput Assist Tomogr. e-Pub 2022. PMID: 35995580.
- Hannan R, Mohamad O, Diaz de Leon A, Manna S, Pop LM, Zhang Z, Mannala S, Christie A, Christley S, Monson N, Ishihara D, Hsu EJ, Ahn C, Kapur P, Chen M, Arriaga Y, Courtney K, Cantarel B, Wakeland EK, Fu YX, Pedrosa I, Cowell L, Wang T, Margulis V, Choy H, Timmerman RD, Brugarolas J. Outcome and Immune Correlates of a Phase II Trial of High-Dose Interleukin-2 and Stereotactic Ablative Radiotherapy for Metastatic Renal Cell Carcinoma. Clin Cancer Res 27(24):6716-6725, 2021. e-Pub 2021. PMID: 34551906.
- Desai S, Jia L, Diaz de Leon A, Costa DN. Rare prostate cancer mimic on multiparametric MRI: Cowper's gland hyperplasia. Urol Case Rep 38:101675, 2021. e-Pub 2021. PMID: 33898268.
- Costa DN, Cai Q, Xi Y, Recchimuzzi DZ, Subramanian N, Bagrodia A, Rofsky NM, Roehrborn CG, Hornberger B, Shah RB, Goldberg K, Diaz de Leon A, Pedrosa I. Gleason Grade Group Concordance between Preoperative Targeted Biopsy and Radical Prostatectomy Histopathologic Analysis: A Comparison Between In-Bore MRI-guided and MRI-Transrectal US Fusion Prostate Biopsies. Radiol Imaging Cancer 3(2):e200123, 2021. e-Pub 2021. PMID: 33817652.
- Subramanian N, Recchimuzzi DZ, Xi Y, Diaz de Leon A, Chen H, Xie D, Goldberg K, Rofsky NM, Pedrosa I, Costa DN. Impact of the Number of Cores on the Prostate Cancer Detection Rate in Men Undergoing in-Bore Magnetic Resonance Imaging-Guided Targeted Biopsies. J Comput Assist Tomogr 45(2):203-209, 2021. e-Pub 2021. PMID: 33273160.
- Courtney KD, Ma Y, Diaz de Leon A, Christie A, Xie Z, Woolford L, Singla N, Joyce A, Hill H, Madhuranthakam AJ, Yuan Q, Xi Y, Zhang Y, Chang J, Fatunde O, Arriaga Y, Frankel AE, Kalva S, Zhang S, McKenzie T, Reig Torras O, Figlin RA, Rini BI, McKay RM, Kapur P, Wang T, Pedrosa I, Brugarolas J. HIF-2 Complex Dissociation, Target Inhibition, and Acquired Resistance with PT2385, a First-in-Class HIF-2 Inhibitor, in Patients with Clear Cell Renal Cell Carcinoma. Clin Cancer Res 26(4):793-803, 2020. e-Pub 2020. PMID: 31727677.
- Yokoo T, Singal AG, Diaz de Leon A, Ananthakrishnan L, Fetzer DT, Pedrosa I, Khatri G. Prevalence and clinical significance of discordant LI-RADS® observations on multiphase contrast-enhanced MRI in patients with cirrhosis. Abdom Radiol (NY) 45(1):177-187, 2020. e-Pub 2020. PMID: 31342103.
- Pirasteh A, Johnson B, Dimitrov IE, Costa DN, Diaz de Leon A, Xi Y, Madhuranthakam AJ, Pedrosa I. Turbo Spin-Echo Diffusion-Weighted Imaging in Prostate Magnetic Resonance Imaging of Men With Pelvic Hardware. J Comput Assist Tomogr 44(4):519-526, 2020. e-Pub 2020. PMID: 32697522.
- Diaz de Leon A, Davenport MS, Silverman SG, Schieda N, Cadeddu JA, Pedrosa I. Role of Virtual Biopsy in the Management of Renal Masses. AJR Am J Roentgenol 212(6):1234-1243, 2019. e-Pub 2019. PMID: 30995092.
- Freifeld Y, Diaz de Leon A, Xi Y, Pedrosa I, Roehrborn CG, Lotan Y, Francis F, Costa DN. Diagnostic performance of prospectively assigned likert scale scores to determine extraprostatic extension and seminal vesicle invasion With multiparametric MRI of the prostate. AJR Am J Roentgenol 212(3):576-581, 2019. e-Pub 2019. PMID: 30589381.
- Diaz de Leon A, Pirasteh A, Costa DN, Kapur P, Hammers H, Brugarolas J, Pedrosa I. Current Challenges in Diagnosis and Assessment of the Response of Locally Advanced and Metastatic Renal Cell Carcinoma. Radiographics 39(4):998-1016, 2019. e-Pub 2019. PMID: 31199711.
- Diaz de Leon A, Costa DN, Francis F, Pedrosa I. Case 258: Granulomatous Prostatitis. Radiology 289(1):267-271, 2018. e-Pub 2018. PMID: 30230997.
- Diaz de Leon A, Leyendecker JR, Otero-Muinelo S, Grewal H, Xi Y, Francis F, Pedrosa I, Costa DN. Reproducibility of Index Lesion Size and Mean Apparent Diffusion Coefficient Values Measured by Prostate Multiparametric MRI: Correlation With Whole-Mount Sectioning of Specimens. AJR Am J Roentgenol 211(4):783-788, 2018. e-Pub 2018. PMID: 30160988.
- Diaz de Leon A, Costa DN, Francis F, Pedrosa I. Case 258. Radiology 287(3):1070-1072, 2018. e-Pub 2018. PMID: 29782240.
- Kay FU, Canvasser NE, Xi Y, Pinho DF, Costa DN, Diaz de Leon A, Khatri G, Leyendecker JR, Yokoo T, Lay AH, Kavoussi N, Koseoglu E, Cadeddu JA, Pedrosa I. Diagnostic Performance and Interreader Agreement of a Standardized MR Imaging Approach in the Prediction of Small Renal Mass Histology. Radiology 287(2):543-553, 2018. e-Pub 2018. PMID: 29390196.
- Mohamad O, Diaz de Leon A, Schroeder S, Leiker A, Christie A, Zhang-Velten E, Trivedi L, Khan S, Desai NB, Laine A, Albuquerque K, Iyengar P, Arriaga Y, Courtney K, Gerber DE, Hammers H, Choy H, Timmerman R, Brugarolas J, Hannan R. Safety and efficacy of concurrent immune checkpoint inhibitors and hypofractionated body radiotherapy. Oncoimmunology 7(7):e1440168, 2018. e-Pub 2018. PMID: 29900043.
- Diaz de Leon A, Pedrosa I. Imaging and screening of kidney cancer. Radiol Clin North Am 55(6):1235-1250, 2017. e-Pub 2017. PMID: 28991563.
- Diaz de Leon A, Costa D, Pedrosa I. Role of Multiparametric MR Imaging in Malignancies of the Urogenital Tract. Magn Reson Imaging Clin N Am 24(1):187-204, 2016. e-Pub 2016. PMID: 26613881.
- Diaz de Leon A, Cronkhite JT, Yilmaz C, Brewington C, Wang R, Xing C, Hsia CCW, Garcia CK. Subclinical lung disease, macrocytosis, and premature graying in kindreds with telomerase (TERT) mutations. Chest 140(3):753-763, 2011. e-Pub 2011. PMID: 21349926.
- Yilmaz C, Watharkar SS, Diaz de Leon A, Garcia CK, Patel NC, Jordan KG, Hsia CC. Quantification of regional interstitial lung disease from CT-derived fractional tissue volume: a lung tissue research consortium study. Acad Radiol 18(8):1014-23, 2011. e-Pub 2011. PMID: 21596593.
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CV information above last modified June 27, 2025