Amy C Moreno, MD
Department of Radiation Oncology, Division of Radiation Oncology
About Dr. Amy C Moreno
Dr. Amy Moreno is an Assistant Professor in the Department of Radiation Oncology. She obtained her medical degree at Yale University where she was recognized as a Farr Scholar for her excellence in research. She then completed her residency training at the University of Texas MD Anderson Cancer Center prior to being appointed as faculty in the Head and Neck Service.
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Dr. Moreno specializes in the management of head and neck cancers with a growing interest in expanding the clinical applications of proton therapy and using highly advanced image-guided techniques such as stereotactic body radiation therapy (SBRT) for the treatment of skull base tumors or recurrent cancers in the re-irradiation setting.
Her research interests are focused on clinical informatics or the improvement of electronic data capture, information retrieval and exchange, and enhancement of clinical knowledge application in our clinics. She is currently in the process of obtaining ABPM board subspecialty certification in Clinical informatics and is involved in multiple departmental committees that focus on the enhancement of existing or developing health information technologies. Her long-term goal is to develop applications and oncology-specific clinical decision support systems that integrate electronically captured patient reported outcomes to improve the quality, efficacy, and efficiency of multidisciplinary cancer care.
Present Title & Affiliation
Primary Appointment
Assistant Professor, Department of Radiation Oncology, Division of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX
Residency Site Director, Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX
Education & Training
Degree-Granting Education
| 2014 | Yale University, New Haven, CT, USA, MD, Doctor of Medicine |
| 2009 | Rice University, Houston, TX, USA, BA, Biochemistry and Cellular Biology |
Postgraduate Training
| 2015-2019 | Clinical Residency, Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX |
| 2014-2015 | Clinical Internship, Internal Medicine, University of California-Irvine, Irvine, CA |
Experience & Service
Administrative Appointments/Responsibilities
Oropharynx Clinical Database Section Lead, Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, 2020 - 2021
Oropharynx Program Leader, The University of Texas MD Anderson Cancer Center, Houston, TX, 2020 - 2020
Stiefel Data Governance Committee Member, The University of Texas MD Anderson Cancer Center, Houston, TX, 2020 - Present
EPIC Development Officer, Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, 2018 - 2020
EPIC Integration Liaison, Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, 2018 - 2020
Institutional Committee Activities
Project 3 Co-Lead, MD Anderson-Varian Alliance, 2019 - Present
Co-Leader, Radiation Oncology Automation Group, 2019 - Present
Member, MDACC Radiation Oncology Annual Program Evaluation Committee, 2018 - 2019
HN Clinical workflow Co-Lead, MDA-RayCare Alliance, 2018 - 2020
Member, Clinical Informatics Committee, 2018 - Present
Member, MD Anderson OnBoarding Task Force Committee, 2016 - 2019
Honors & Awards
| 2019 | Neuosoft Certificate Scholarship |
| 2018 | 2018 National Comprehensive Cancer Network Fellows Program |
| 2014 | Cum Laude, Yale University School of Medicine |
| 2013 | William U Gardener Memorial Student Research Fellowship |
| 2012 | Yale School of Medicine Medical Student Research Fellowship, Yale School of Medicine |
| 2012 | NIH-NCRR-TL1 Medical Student Research Fellowship, NIH |
| 2011 | Yale University Seton Elm Ivy Award, Yale University |
| 2010 | NIH-NHLBI Medical Student Research Fellowship, NIH |
| 2009 | Cum Laude, Rice University |
Professional Memberships
Selected Publications
Peer-Reviewed Articles
- van Dijk LV, Frank SJ, Yuan Y, Gunn GB, Moreno AC, Mohamed ASR, Preston KE, Qing Y, Spiotto MT, Morrison WH, Lee A, Phan J, Garden AS, Rosenthal DI, Langendijk JA, Fuller CD. Proton Image-guided Radiation Assignment for Therapeutic Escalation via Selection of locally advanced head and neck cancer patients [PIRATES]: A Phase I safety and feasibility trial of MRI-guided adaptive particle radiotherapy. Clin Transl Radiat Oncol 32:35-40, 2022. e-Pub 2021. PMID: 34841093.
- Amit M, Liu C, Mansour J, Gleber-Netto FO, Tam S, Baruch EN, Aashiq M, El-Naggar AK, Moreno AC, Rosenthal DI, Glisson BS, Ferrarotto R, Wong MK, Tsai K, Flores ER, Migden MR, Silverman DA, Li G, Khanna A, Goepfert RP, Nagarajan P, Weber RS, Myers JN, Gross ND. Elective neck dissection versus observation in patients with head and neck cutaneous squamous cell carcinoma. Cancer 127(23):4413-4420, 2021. e-Pub 2021. PMID: 34358340.
- Diao K, Nguyen TP, Moreno AC, Reddy JP, Garden AS, Wang CH, Tung S, Wang C, Wang XA, Rosenthal DI, Fuller CD, Gunn GB, Frank SJ, Morrison WH, Shah SJ, Lee A, Spiotto MT, Su SY, Ferrarotto R, Phan J. Stereotactic body ablative radiotherapy for reirradiation of small volume head and neck cancers is associated with prolonged survival: A large, single-institution, modern cohort study. Head Neck 43(11):3331-3344, 2021. e-Pub 2021. PMID: 34269492.
- Lovin BD, Hernandez M, Elms H, Choi JS, Lindquist NR, Moreno AC, Nader ME, Gidley PW. Temporal Bone Osteoradionecrosis: An 18-year, Single-Institution Experience. Laryngoscope 131(11):2578-2585, 2021. e-Pub 2021. PMID: 34287898.
- Guo TW, Saiyed F, Yao CMKL, Kiong KL, Martinez J, Sacks R, Lee JJ, Moreno AC, Frank SJ, Rosenthal DI, Glisson BS, Ferrarotto R, Mott FE, Johnson FM, Myers JN. Outcomes of patients with oropharyngeal squamous cell carcinoma treated with induction chemotherapy followed by concurrent chemoradiation compared with those treated with concurrent chemoradiation. Cancer 127(16):2916-2925, 2021. e-Pub 2021. PMID: 33873251.
- van Dijk LV, Mohamed ASR, Ferrarotto R, McCoy LA, Sharafi CS, Jones E, Steele K, Moreno AC, Lai SY, Garden AS, Myers JN, Rosenthal DI, Fuller CD, Hutcheson KA, for MD Anderson Symptom Working Group. The impact of induction and/or concurrent chemoradiotherapy on acute and late patient-reported symptoms in oropharyngeal cancer: Application of a mixed-model analysis of a prospective observational cohort registry. Cancer 127(14):2453-2464, 2021. e-Pub 2021. PMID: 33788956.
- Taku N, Wang L, Garden AS, Rosenthal DI, Gunn GB, Morrison WH, Fuller CD, Phan J, Reddy JP, Moreno AC, Spiotto MT, Chronowski G, Shah SJ, Mayo LL, Gross ND, Ferrarotto R, Zhu XR, Zhang X, Frank SJ. Proton Therapy for HPV-Associated Oropharyngeal Cancers of the Head and Neck: a De-Intensification Strategy. Curr Treat Options Oncol 22(6):54, 2021. e-Pub 2021. PMID: 34086150.
- Amit M, Liu C, Gleber-Netto FO, Kini S, Tam S, Benov A, Aashiq M, El-Naggar AK, Moreno AC, Rosenthal DI, Glisson BS, Ferrarotto R, Wong MK, Migden MR, Baruch EN, Li G, Khanna A, Goepfert RP, Nagarajan P, Weber RS, Myers JN, Gross ND. Inclusion of extranodal extension in the lymph node classification of cutaneous squamous cell carcinoma of the head and neck. Cancer 127(8):1238-1245, 2021. e-Pub 2020. PMID: 33320343.
- Rasing MJA, Peters M, Moreno AC, Hofman EFN, Herder GJM, Welvaart PWN, Schramel FMNH, Lodeweges JE, Lin SH, Verhoeff JJC, van Rossum PSN. Predicting incomplete resection in non-small cell lung cancer preoperatively: a validated nomogram. Ann Thorac Surg 111(3):1052-1058, 2021. e-Pub 2020. PMID: 32739254.
- Amit M, Liu C, Netto Gleber FO, Kini S, Tam S, Benov A, Aashiq M, El-Naggar AK, Moreno AC, Rosenthal DI, Glisson BS, Ferrarotto R, Wong MK, Migden MR, Li G, Khanna A, Goepfert RP, Nagarajan P, Weber RS, Myers JN, Gross ND. Integrating depth of invasion in T classification improves the prognostic performance of the American Joint Committee on Cancer primary tumor staging system for cutaneous squamous cell carcinoma of the head and neck. Eur J Cancer 144:169-177, 2021. e-Pub 2020. PMID: 33352413.
- Christopherson KM, Moreno AC, Elgohari B, Gross N, Ferrarotto R, Mohamed ASR, Gunn GB, Goepfert RP, Mott FE, Shah SJ, David Fuller C, Reddy JP, Frank SJ, Morrison WH, Phan J, Rosenthal DI, Garden AS. Outcomes after salvage for HPV-positive recurrent oropharyngeal cancer treated with primary radiation. Oral Oncol 113:105125, 2021. e-Pub 2020. PMID: 33360375.
- Wilke C, Takiar V, Wang H, Moreno AC, Tung SS, Quinlan-Davidson SR, Garden AS, Rosenthal DI, Fuller CD, Gunn GB, Reddy JP, Morrison WH, Wang C, Zhao G, Hutcheson KA, Phan J. Defining the dose-volume criteria for laryngeal sparing in locally advanced oropharyngeal cancer utilizing split-field IMRT, whole-field IMRT and VMAT. J Appl Clin Med Phys 22(1):37-44, 2021. e-Pub 2020. PMID: 33277960.
- Zhu LL, Martin RM, Gunther JR, Wong PF, Hancock D, Moreno AC, Dabaja BS, Pinnix CC. Daily computed tomography image guidance: dosimetric advantages outweigh low-dose radiation exposure for treatment of mediastinal lymphoma. Radiother Oncol 152:14-18, 2020. e-Pub 2020. PMID: 32593645.
- Bagley AF, Garden AS, Reddy JP, Moreno AC, Frank SJ, Rosenthal DI, Morrison WH, Gunn GB, Fuller CD, Shah SJ, Ferrarotto R, Sturgis EM, Gross ND, Phan J. Highly conformal reirradiation in patients with prior oropharyngeal radiation: Clinical efficacy and toxicity outcomes. Head Neck 42(11):3326-3335, 2020. e-Pub 2020. PMID: 32776401.
- Moreno AC, Gunther JR, Milgrom S, Fuller CD, Williamson T, Liu A, Wu R, Zhu XR, Dabaja BS, Pinnix CC. Effect of Deep Inspiration Breath Hold on Normal Tissue Sparing With Intensity Modulated Radiation Therapy Versus Proton Therapy for Mediastinal Lymphoma. Adv Radiat Oncol 5(6):1255-1266, 2020. e-Pub 2020. PMID: 33305086.
- Grant SR, Williamson TD, Stieb S, Shah SJ, David Fuller C, Rosenthal DI, Frank SJ, Garden AS, Morrison WH, Phan J, Moreno AC, Reddy JP, Cardoso RC, Liu AY, Wu RY, Gunn GB. A Dosimetric Comparison of Oral Cavity Sparing in the Unilateral Treatment of Early Stage Tonsil Cancer: IMRT, IMPT, and Tongue-Deviating Oral Stents. Adv Radiat Oncol 5(6):1359-1363, 2020. e-Pub 2020. PMID: 33305099.
- Moreno AC, Lin SH. Authors' Reply to Yajing Du's Letter to the Editor on "Biologically Effective Dose in Stereotactic Body Radiotherapy and Survival for Patients With Early-Stage NSCLC". J Thorac Oncol 15(10):e166-e168, 2020. PMID: 32981605.
- Mesko S, Wang H, Tung S, Wang C, Pasalic D, Ning MS, Pezzi TA, Moreno AC, Reddy JP, Garden AS, Rosenthal DI, Gunn GB, Frank SJ, Fuller CD, Morrison W, Su SY, Hanna E, Phan J. Stereotactic Ablative Radiotherapy (SABR) for skull base malignancies: a systematic analysis of set-up and positioning accuracy. Pract Radiat Oncol 10(5):363-371, 2020. e-Pub 2020. PMID: 32240823.
- Jiang W, Verma V, Haque W, Moreno AC, Koshy M, Butler EB, Teh BS. Post-treatment mortality after definitive chemoradiotherapy versus resection for esophageal cancer. Dis Esophagus 33(4), 2020. PMID: 31504359.
- Moreno AC, Fellman B, Hobbs BP, Liao Z, Gomez DR, Chen A, Hahn SM, Chang JY, Lin SH. Biologically Effective Dose in Stereotactic Body Radiotherapy and Survival for Patients with Early-Stage Non-Small Cell Lung Cancer. J Thorac Oncol 15(1):101-109, 2020. e-Pub 2019. PMID: 31479748.
- Mesko S, Wang H, Tung S, Wang C, Pasalic D, Chapman BV, Moreno AC, Reddy JP, Garden AS, Rosenthal DI, Gunn GB, Frank SJ, Fuller CD, Morrison W, Phan J. Estimating PTV margins in head and neck stereotactic ablative radiation therapy (SABR) through target site analysis of positioning and intrafractional accuracy. Int J Radiat Oncol Biol Phys 106(1):185-193, 2020. e-Pub 2019. PMID: 31580928.
- Cushman TR, Shaaban SG, Moreno AC, Lin C, Verma V. Management of Unresectable T4b Esophageal Cancer: Practice Patterns and Outcomes From the National Cancer Data Base. Am J Clin Oncol 42(2):154-159, 2019. PMID: 30499838.
- Moreno AC, Zhang N, Verma V, Giordano SH, Lin SH. Treatment disparities affect outcomes for patients with stage I esophageal cancer: a national cancer data base analysis. J Gastrointest Oncol 10(1):74-84, 2019. PMID: 30788162.
- Moreno AC, Lin SH. The optimal treatment approaches for stage I small cell lung cancer. Transl Lung Cancer Res 8(1):88-96, 2019. PMID: 30788238.
- Moreno AC, Frank SJ, Garden AS, Rosenthal DI, Fuller CD, Gunn GB, Reddy JP, Morrison WH, Williamson TD, Holliday EB, Phan J, Blanchard P. Intensity modulated proton therapy (IMPT) - The future of IMRT for head and neck cancer. Oral Oncol 88:66-74, 2019. e-Pub 2018. PMID: 30616799.
- Fang P, Musall BC, Son JB, Moreno AC, Hobbs BP, Carter BW, Fellman BM, Mawlawi O, Ma J, Lin SH. Multimodal Imaging of Pathologic Response to Chemoradiation in Esophageal Cancer. Int J Radiat Oncol Biol Phys 102(4):996-1001, 2018. e-Pub 2018. PMID: 29685377.
- Matuszak MM, Fuller CD, Yock TI, Hess CB, McNutt T, Jolly S, Gabriel P, Mayo CS, Thor M, Caissie A, Rao A, Owen D, Smith W, Palta J, Kapoor R, Hayman J, Waddle M, Rosenstein B, Miller R, Choi S, Moreno AC, Herman J, Feng M. Performance/outcomes data and physician process challenges for practical big data efforts in radiation oncology. Med Phys 45(10):e811-e819, 2018. e-Pub 2018. PMID: 30229946.
- Moreno AC, Haque W, Verma V, Fang P, Lin SH. Concurrent Versus Sequential Chemoradiation Therapy in Completely Resected Pathologic N2 Non-Small Cell Lung Cancer: Propensity-Matched Analysis of the National Cancer Data Base. Ann Surg Oncol 25(5):1245-1253, 2018. e-Pub 2018. PMID: 29484562.
- Verma V, Surkar SM, Moreno AC, Lin C, Simone CB. Practice patterns and outcomes of chemoradiotherapy versus radiotherapy alone for older patients with nasopharyngeal cancer. Cancer Med 7(5):1604-1611, 2018. e-Pub 2018. PMID: 29603669.
- Verma V, Moreno AC, Haque W, Fang P, Lin SH. Sequential Versus Concurrent Chemoradiation Therapy by Surgical Margin Status in Resected Non-Small Cell Lung Cancer. J Natl Compr Canc Netw 16(5):508-516, 2018. PMID: 29752325.
- Corso CD, Park HS, Moreno AC, Kim AW, Yu JB, Husain ZA, Decker RH. Stage I Lung SBRT Clinical Practice Patterns. Am J Clin Oncol 40(4):358-361, 2017. PMID: 25503436.
- Moreno AC, Shaitelman SF, Buchholz TA. A clinical perspective on regional nodal irradiation for breast cancer. Breast 34 Suppl 1:S85-S90, 2017. e-Pub 2017. PMID: 28690104.
- Moreno AC, Verma V, Hofstetter WL, Lin SH. Patterns of Care and Treatment Outcomes of Elderly Patients with Stage I Esophageal Cancer: Analysis of the National Cancer Data Base. J Thorac Oncol 12(7):1152-1160, 2017. e-Pub 2017. PMID: 28455149.
- Moreno AC, Lin YH, Bedrosian I, Shen Y, Stauder MC, Smith BD, Buchholz TA, Babiera GV, Woodward WA, Shaitelman SF. Use of regional nodal irradiation and its association with survival for women with high-risk, early stage breast cancer: A National Cancer Database analysis. Adv Radiat Oncol 2(3):291-300, 2017. e-Pub 2017. PMID: 29114595.
- Xu C, Xi M, Moreno A, Shiraishi Y, Hobbs BP, Huang M, Komaki R, Lin SH. Definitive Chemoradiation Therapy for Esophageal Cancer in the Elderly: Clinical Outcomes for Patients Exceeding 80 Years Old. Int J Radiat Oncol Biol Phys 98(4):811-819, 2017. e-Pub 2017. PMID: 28602412.
- Verma V, Moreno AC, Lin SH. Advances in Radiotherapy Management of Esophageal Cancer. J Clin Med 5(10), 2016. e-Pub 2016. PMID: 27775643.
- Liu J, Hancock JG, Moreno AC, Wang Z, Boffa DJ, Detterbeck FC, Kim AW. Evaluating the fate of patients who undergo resections of very large, node-negative lung cancers using the National Cancer DataBase. Eur J Cardiothorac Surg 49(2):596-601, 2016. e-Pub 2015. PMID: 25890936.
- Hancock JG, Rosen JE, Antonicelli A, Moreno A, Kim AW, Detterbeck FC, Boffa DJ. Impact of adjuvant treatment for microscopic residual disease after non-small cell lung cancer surgery. Ann Thorac Surg 99(2):406-13, 2015. e-Pub 2014. PMID: 25528723.
- Boffa DJ, Hancock JG, Yao X, Goldberg S, Rosen JE, Kim AW, Moreno A, Detterbeck FC. Now or later: evaluating the importance of chemotherapy timing in resectable stage III (N2) lung cancer in the National Cancer Database. Ann Thorac Surg 99(1):200-8, 2015. e-Pub 2014. PMID: 25440272.
- Hancock J, Rosen J, Moreno A, Kim AW, Detterbeck FC, Boffa DJ. Management of clinical stage IIIA primary lung cancers in the National Cancer Database. Ann Thorac Surg 98(2):424-32; discussion 432, 2014. e-Pub 2014. PMID: 24929895.
- Moreno AC, Morgensztern D, Boffa DJ, Decker RH, Yu JB, Detterbeck FC, Wang Z, Rose MG, Kim AW. Treating locally advanced disease: an analysis of very large, hilar lymph node positive non-small cell lung cancer using the National Cancer Data Base. Ann Thorac Surg 97(4):1149-55, 2014. e-Pub 2014. PMID: 24582051.
- Moreno AC, Morgensztern D, Yu JB, Boffa DJ, Decker RH, Detterbeck FC, Kim AW. Impact of preoperative radiation on survival of patients with T3N0 >7-cm non-small cell lung cancers treated with anatomic resection using the Surveillance, Epidemiology, and End Results database. J Surg Res 184(1):10-8, 2013. e-Pub 2013. PMID: 23583079.
- Moreno AC, Akcakanat A, Munsell MF, Soni A, Yao JC, Meric-Bernstam F. Antitumor activity of rapamycin and octreotide as single agents or in combination in neuroendocrine tumors. Endocr Relat Cancer 15(1):257-66, 2008. PMID: 18310292.
- Kim E, Bitterman DS, Kann BH, Mak RH, Moreno AC, Upadhyay VA, Warner JL, Zhang HM. Hidden in Plain Sight: Clinical Informaticians are the Oncology Subspecialists You Did Not Know You Needed. Clin Oncol (R Coll Radiol). e-Pub 2021. PMID: 34887151.
- Barbon CEA, Yao CMK, Peterson CB, Moreno AC, Goepfert RP, Johnson FM, Chronowski GM, Fuller CD, Gross ND, Hutcheson KA. Swallowing After Primary TORS and Unilateral or Bilateral Radiation for Low- to Intermediate-Risk Tonsil Cancer. Otolaryngol Head Neck Surg:1945998211059967. e-Pub 2021. PMID: 34784256.
- Grant SR, Hutcheson KA, Ye R, Garden AS, Morrison WH, Rosenthal DI, Gunn BG, Fuller CD, Phan J, Reddy JP, Moreno AC, Lewin JS, Sturgis EM, Ferrarotto R, Frank SJ. Prospective longitudinal patient-reported outcomes of swallowing following intensity modulated proton therapy for oropharyngeal cancer. Radiother Oncol 148:133-139. e-Pub 2020. PMID: 32361662.
Book Chapters
- Moreno AC. Breast Cancer. In: Pocket Radiation Oncology. Wolters Kluwer, 2019.
- Moreno AC, Kudchadker RJ, Wang J, Frank S. MRI Image-Guided LDR Brachytherapy for Prostate Cancer. In: Handbook of Image-Guided Brachytherapy. Springer, 2017.