Amy Spallone, M.D.
Department of Infectious Diseases, Infection Control, and Employee Health, Division of Internal Medicine
Present Title & Affiliation
Primary Appointment
Chief Infection Control Officer, Department of Ofc of Chief Operating Officer, Chief Quality Office, Division of Internal Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas
Chair Infection Control Committee, The University of Texas MD Anderson Cancer Center, Houston, Texas
Patient Quality Safety Officer, Department of Infectious Diseases, Infection Control and Employee Health, The University of Texas MD Anderson Cancer Center, Houston, TX
Assistant Professor, Department of Infectious Diseases, Infection Control and Employee Health, The University of Texas MD Anderson Cancer Center, Houston, TX
Dual/Joint/Adjunct Appointment
Assistant Professor, Department of Infectious Diseases, Infection Control and Employee Health, The University of Texas MD Anderson Cancer Center, Houston, Texas
Education & Training
Degree-Granting Education
| 2015 | Albany Medical College, Albany, New York, US, MD |
| 2010 | Cornell University, Ithaca, New York, US, BS in Biological Sciences |
| 2008 | Corning Community College, Corning, New York, US, Associate in Mathematics and Sciences |
Postgraduate Training
| 2024-2025 | FY25 LEADing Teams Core Cohort, The University of Texas MD Anderson Cancer Center, Houston, Texas |
| 2022-2022 | Clinical Safety and Effectiveness (CS&E) Cohort 33, The University of Texas MD Anderson Cancer Center, Houston, Texas |
| 2020-2021 | Infectious Diseases Advanced Research Fellowship, Baylor College of Medicine, Houston, Texas |
| 2019-2020 | Clinical Scientist Training Program Certificate of Added Qualification, Baylor College of Medicine Graduate School of Biomedical Sciences, Houston, Texas |
| 2018-2020 | Infectious Diseases Fellowship Program, Baylor College of Medicine, Houston, Texas |
| 2015-2018 | Internal Medicine Internship and Residency, Stony Brook University Hospital, Stony Brook, New York |
Licenses & Certifications
| 2025 | Adult Mental Health First Aid |
| 2023 | Arizona Medical Board |
| 2023 | Mississippi State Board of Medical Licensure |
| 2023 | Alabama Board of Medical Examiners |
| 2023 | Washington Medical Commission |
| 2023 | Oklahoma State Board of Medical Licensure & Supervision |
| 2023 | Louisiana Medical Board |
| 2023 | Tennessee Board of Medical Examiners |
| 2021 | Florida State Medical License |
| 2021 | Georgia Composite Medical Board |
| 2021 | Texas Medical Board |
| 2020 | American Board of Internal Medicine |
| 2018 | American Board of Internal Medicine |
Experience & Service
Administrative Appointments/Responsibilities
Incident Commander, Department of Institutional Emergency Management, The University of Texas MD Anderson Cancer Center, Houston, Texas, 2024 - Present
Chief Infection Control Officer, Department of Ofc of the Chief Operating Officer, Chief Quality Office, The University of Texas MD Anderson Cancer Center, Houston, Texas, 2023 - Present
Department Patient Safety Quality Officer, Department of Infectious Diseases, Infection Control and Employee Health, The University of Texas MD Anderson Cancer Center, Houston, Texas, 2023 - Present
Chief Infection Control Officer, ad interim, Department of Office of the Chief Operating Officer, The University of Texas MD Anderson Cancer Center, Houston, Texas, 2023 - 2023
Associate Chief Infection Control Officer, Department of Chief Quality Office, The University of Texas MD Anderson Cancer Center, Houston, Texas, 2021 - 2023
Institutional Committee Activities
Member, Clinical Operations Impact Review Committee (COIRC), 2025 - Present
Member, Division of Internal Medicine Wellness Committee, 2024 - Present
Chair, Infectious Diseases Engagement & Wellness Committee, 2024 - Present
Chair, Infection Control Leaders' Forum, 2023 - Present
Executive Sponsor, Antimicrobial Stewardship Committee, 2023 - Present
Voting Member, Travel Oversight Committee, 2023 - Present
Chair, Infection Control Committee (ICC), 2023 - Present
Voting Member, Clinical Core Leadership Team (CCLT), 2023 - Present
Voting Member, Executive Committee of the Medical Staff (ECMS), 2023 - Present
Voting Member, Institutional Survey Readiness Steering Committee (ISRSC), 2023 - Present
Vice Chair, Infection Control Committee (ICC), 2022 - 2023
Voting Member, Quality Assurance Performance Improvement (QAPI), 2022 - Present
Member, Infectious Diseases Engagement & Wellness Committee, 2022 - 2024
Voting Member, Institutional Patient Safety Committee (IPSC), 2022 - Present
Member, Antimicrobial Stewardship Committee, 2021 - 2023
Non-Voting Member, ESCMID Study Group for Respiratory Viruses (ESGREV), 2021 - Present
Member, Steering Committee for Stem Cell Transplantation and Cellular Therapy, Infectious Diseases, 2021 - Present
Member, Division of Internal Medicine Quality & Safety Council, 2021 - Present
Honors & Awards
| 2026 - Present | Distinguished Alumni Award, Corning Community College |
| 2025 - Present | “Stellar” Excellence Awards in the Excellence in Patient Care, Division of Internal Medicine |
| 2024 | Certificate of Appreciation and Excellence, MD Anderson Cancer Center, Chief Quality Office |
| 2022 | Clinical Safety & Effectiveness Program Certificate of Successful Completion, The University of Texas MD Anderson Cancer Center Clinical Safety & Effectiveness Program |
| 2020 - 2021 | Outstanding Graduating Fellow, Baylor College of Medicine |
| 2015 | The One-to-Watch Award, Corning Community College |
| 2014 | MD Trustee Scholarship, Morris Alpert Alumni Scholarship |
| 2010 | Brooks Family Award for Swedish 1220, Cornell University |
| 2010 | Cornell Center for Materials Research Microscopy Award in Biological Category; Brooks Family Award for Swedish 1220, Cornell University |
| 2008 | Institutional Honors with Distinction, State University of New York Chancellor’s Award for Student Excellence |
Professional Memberships
Selected Presentations & Talks
Local Presentations
- 2025. Institutional alignment with ASHRAE 170-2008 for survey readiness. Invited. Division of Surgery Continuous Quality Improvement Committee. Houston, Texas, US.
- 2025. Institutional alignment with ASHRAE 170-2008 for survey readiness. Invited. Division of Surgery Executive Committee. Houston, Texas, US.
- 2025. Institutional alignment with ASHRAE 170-2008 for survey readiness. Invited. Core Clinical Leadership Team. Houston, Texas, US.
- 2025. Infection Prevention & Control in a Comprehensive Cancer Center. Invited. Infection Prevention and Antimicrobial Stewardship Conference Series. Houston, Texas, US.
- 2025. Infection Control Updates on Measles. Invited. Clinical Enterprise Leaders Live. Houston, Texas, US.
- 2025. Update: Becton Dickinson (BD) BACTEC™ Blood Culture Bottle Critical Shortage. Invited. Core Clinical Leadership Team. Houston, Texas, US.
- 2025. Respiratory Viral Season Updates. Invited. Clinical Enterprise Leaders Live. Houston, Texas, US.
- 2024. Respiratory Viral Season Updates and Masking Protocols. Invited. Clinical Enterprise Leaders Live. Houston, Texas, US.
- 2024. COVID-19 Updates. Invited. Clinical Enterprise Leaders Live. Houston, Texas, US.
- 2024. Becton Dickinson (BD) BACTEC™ Blood Culture Bottle Critical Shortage. Invited. Core Clinical Leadership Team. Houston, Texas, US.
- 2024. Respiratory Virus Report and Updated COVID-19 Protocols. Invited. Clinical Enterprise Leaders Live. Houston, Texas, US.
- 2024. COVID-19 Perspectives and the Path Forward. Invited. President’s Advisory Council. Houston, Texas, US.
- 2024. Keynote Speaker: The What, Why, and How of Quality Improvement. Invited. MD Anderson 2024 Division of Pharmacy Quality and Research Celebration. Houston, Texas, US.
- 2024. COVID-19 Perspectives and the Path Forward. Invited. Core Clinical Leadership Team. Houston, Texas, US.
- 2024. Staying Alert: Update on Measles in the U.S. Invited. Clinical Enterprise Leaders Live. Houston, Texas, US.
- 2024. Infection Control Update – Respiratory Viral Season. Invited. Core Clinical Leadership Team. Houston, Texas, US.
- 2023. COVID-19 De-escalation Updates. Invited. Clinical Enterprise Leaders Live. Houston, Texas, US.
- 2023. COVID-19 Updates. Invited. Core Clinical Leadership Team. Houston, Texas, US.
- 2023. COVID-19 Updates & Infection Control Recommendations. Invited. Core Clinical Leadership Team. Houston, Texas, US.
- 2022. Monkeypox Global-to-Local Updates. Invited. Infection Control Committee. Houston, Texas, US.
- 2022. Monkeypox update. Invited. PA Senate Meeting. Houston, Texas, US.
- 2022. Institutional Monkeypox education. Invited. APRN Counsel Meeting. Houston, Texas, US.
- 2022. Monkeypox Outbreak 2022. Invited. ICT Grand Rounds. Houston, Texas, US.
- 2022. Institutional Monkeypox education. Invited. APP Managers/Supervisors Forum. Houston, Texas, US.
- 2022. Monkeypox update. Invited. Infectious Diseases Case Conference. Houston, Texas, US.
- 2022. Institutional Monkeypox education. Invited. Ambulatory Leaders Forum. Houston, Texas, US.
- 2022. Institutional Townhall and Q&A on Monkeypox. Invited. LGBTQ+ Community Townhall. Houston, Texas, US.
- 2022. Institutional Monkeypox Education. Invited. Acute Care Center/Clinical Decision Making Unit Staff Meeting. Houston, Texas, US.
- 2022. Monkeypox Updates. Invited. Infection Control Committee. Houston, Texas, US.
- 2022. Institutional Monkeypox Education. Invited. International Center. Houston, Texas, US.
- 2022. Monkeypox Outbreak 2022. Invited. LGBTQ+ Network Meeting. Houston, Texas, US.
- 2022. Monkeypox updates. Invited. Infection Control Committee. Houston, Texas, US.
National Presentations
- 2023. Post COVID-19 Implications: The Lasting Impact on a Comprehensive Cancer Center. Invited. Scripps MD Anderson Cancer Center’s 2023 Cancer Care Symposium. San Diego, CA, US.
- 2023. The COVID-19 Pandemic: The Impact on a Comprehensive Cancer Hospital. Invited. 2023 Cancer Network Speaker's Bureau, US.
International Presentations
- 2025. Measles in older adults - are they really protected?. Invited. How, when, what - should I vaccinate my elderly patient?. Basil, CH.
- 2025. The Re-emergence of Measles in the United States: A Call to Action in Cancer Medicine. Invited. Breaking the Chain: Stopping Measles Before It Reaches the Most Vulnerable/ICHS in Collaboration with ESGREV from ESCMID, US.
- 2023. Prevention of RVIs: Infection control, vaccines, monoclonals and antivirals. Invited. ESCMID Postgraduate Educational Course: Update on Infections in Immunocompromised Host. Basel, CH.
- 2022. Hospital-acquired COVID-19 and other respiratory viral infections during the pandemic: What we learned. Invited. ESGREV/ESCMID Webinar: The Interplay of Respiratory Viruses and COVID-19: Re-emergence of Respiratory Viral Seasonality and the New Normal After the Pandemic. Basel, CH.
- 2022. Taking a closer look: Clinical and histopathological characteristics of culture-positive versus culture-negative pulmonary mucormycosis. Invited. 10th Advances Against Aspergillosis and Mucormycosis. Manchest, GB.
Formal Peers
- 2025. Infection Control Updates. Houston, Texas, US.
- 2025. Measles: Identify, Isolate, and Inform. Houston, Texas, US.
- 2025. Infection Control: Don’t just think it through…think ahead!. Houston, Texas, US.
- 2025. Infection Control: Don’t just think it through…think ahead!. Houston, Texas, US.
- 2025. Stem Cell Therapy Quality Meeting: Infection Control Updates. Houston, Texas, US.
- 2025. Infection Control: Don’t just think it through…think ahead!. Houston, Texas, US.
- 2024. Stem Cell Therapy Quality Meeting: Infection Control Updates. Houston, Texas, US.
- 2024. Candida auris Screening and Monitoring in the ICU. Houston, Texas, US.
- 2024. Infection Control Updates. Houston, Texas, US.
- 2023. Stem Cell Therapy Quality Meeting: Infection Control Updates. Houston, Texas, US.
- 2023. Infection Control Updates. Houston, Texas, US.
- 2023. Stem Cell Therapy Quality Meeting: Infection Control Updates. Houston, Texas, US.
- 2023. Infection Control Updates. Houston, Texas, US.
- 2022. Monkeypox Outbreak and Updates. Invited. Houston, Texas, US.
- 2022. Infection Control Updates. Houston, Texas, US.
- 2018. Medically Significant Zoonosis of Cats and Dogs. Invited. Ithaca, NY, US.
- 2014. Post Travel Fever. Invited. Albany, NY, US.
Grant & Contract Support
| Date: | 2024 - Present |
| Title: | A Phase 2 Multiple Dose Study to Evaluate the Efficacy and Safety of PUL-042 Inhalation Solution in Reducing Lower Respiratory Tract Complications in Patients with Hematologic Malignancies and Recipients of Hematopoietic Stem Cell Transplantation (HSCT) with Documented Viral Infections with Parainfluenza Virus (PIV), Human Metapneumovirus (hMPV) or Respiratory Syncytial Virus (RSV) |
| Funding Source: | Pulmotech Inc |
| Role: | PI |
| ID: | 2024-1050-MDACC, PUL-042-207 |
| Date: | 2022 - 2025 |
| Title: | The impact of a Filtered Far ultraviolet-C handheld disinfection device on reducing healthcare environmental pathogens from high-touch surfaces in clinical working rooms |
| Funding Source: | FreeStyle, LLC |
| Role: | PI |
| ID: | 2022-0512-MDACC, AWD00006978 |
| Date: | 2020 - 2021 |
| Title: | Infection and Immunity NIH T32 AI055413 Training Grant |
| Funding Source: | NIH/NIAID |
| Role: | Postdoctoral Fellow |
| ID: | T32 AI055413 Training Grant |
Selected Publications
Peer-Reviewed Articles
- Yaghi L, Chemaly RF, Wilson-Dib R, Shropshire WC, Cantu S, Bhatti M, Chatterjee P, Jinadatha C, Spallone A. The efficacy of a filtered handheld far-ultraviolet disinfection device for decontamination of high-touch surfaces in healthcare settings: A genomic bacterial analysis. Infection Control & Hospital Epidemiology (ICHE), 2025. e-Pub 2025.
- Shafat, T, De-La-Rosa-Martinez, D, Khawaja, F, Jiang, Y, Spallone, A, Batista, MV, Ariza Heredia, E, Vilar-Compte, D, Ahmed, S, Becnel, M, Chemaly, RF. Outcomes and Risk Factors for Influenza and Respiratory Syncytial Virus Lower Respiratory Tract Infections and Mortality in Patients With Lymphoma or Multiple Myeloma. Open Forum Infectious Diseases 12(4), 2025. e-Pub 2025. PMID: 40177586.
- Daher, M, Khawaja, F, Spallone, A, Shigle, TL, Bhatti, MM, Vuong, NN, Ariza Heredia, E, Mulanovich, VE, Champlin, RE, Chemaly, RF. Real-World Experience With Maribavir for Treatment of Refractory or Resistant Cytomegalovirus Infection in Hematopoietic Cell Transplant Recipients and Hematologic Malignancy Patients. Transplant Infectious Disease 27(2), 2025. e-Pub 2025. PMID: 39826146.
- Wu, CT, Shropshire, W, Bhatti, MM, Cantu, S, Glover, I, Anand, SS, Liu, X, Kalia, A, Treangen, TJ, Chemaly, RF, Spallone, A, Shelburne, S. Rapid whole genome characterization of antimicrobial-resistant pathogens using long-read sequencing to identify potential healthcare transmission. Infection Control and Hospital Epidemiology 46(2):129-135, 2025. e-Pub 2025. PMID: 39727230.
- Lee YJ, Shafat T, Li Y, Shah GL, Spallone A, Obeid K, Djoverti V, Hammond SP, Young JH, Hill JA, Chemaly RF, Papanicolaou GA. Foscarnet Treatment for Human Herpes Simplex Virus Infection Resistant to Acyclovir after Hematopoietic Cell Transplantation. ASTCT 2025 31(2):S509, 2025. e-Pub 2025.
- Azuly, H, Shafat, T, Grupel, D, Porges, T, Abuhasira, R, Belkin, A, Deri, O, Oster, Y, Zahran, S, Horwitz, E, Horwitz, N, Khatib, H, Batista, MV, Cortez, AC, Brosh-Nissimov, T, Segman, Y, Ishay, L, Cohen, R, Atamna, A, Spallone, A, Chemaly, RF, Ramos, JC, Chowers, M, Rogozin, E, Oren, NC, Keske, Ş, Barchad, OW, Nesher, L, Nesher, L. Preventing Severe COVID-19 with Tixagevimab-Cilgavimab in Hematological Patients Treated with Anti-CD20 Monoclonal Antibodies. Infectious Diseases and Therapy 14(1):167-180, 2025. e-Pub 2025. PMID: 39652286.
- Khawaja, F, Ahmed, S, Iyer, S, Sassine, J, Handley, G, Prakash, R, Vanwierren, T, Jackson, J, Zubovskaia, A, Ramdial, JL, Rondon, G, Patel, K, Spallone, A, Ariza Heredia, E, Mulanovich, VE, Angelidakis, G, Jiang, Y, Chemaly, RF. Cytomegaloviral Infections in Recipients of Chimeric Antigen Receptor T-Cell Therapy. Open Forum Infectious Diseases 11(8), 2024. e-Pub 2024. PMID: 39086466.
- Febres-Aldana, A, Khawaja, F, Morado-Aramburo, O, Shigle, TL, Rondon, G, Sassine, J, Spallone, A, Srinivasan, K, Ramdial, JL, Alousi, AM, Champlin, RE, Chen, GL, Daher, M, Rezvani, K, Ariza Heredia, E, Shpall, E, Chemaly, RF. Mortality in recipients of allogeneic haematopoietic cell transplantation in the era of cytomegalovirus primary prophylaxis. Clinical Microbiology and Infection 30(6):803-809, 2024. e-Pub 2024. PMID: 38460821.
- Shafat, T, Grupel, D, Porges, T, Abuhasira, R, Belkin, A, Deri, O, Oster, Y, Zahran, S, Horwitz, E, Horwitz, N, Khatib, H, Batista, MV, Cortez, AC, Brosh-Nissimov, T, Segman, Y, Ishay, L, Cohen, R, Atamna, A, Spallone, A, Chemaly, RF, Ramos-Ramos, JC, Chowers, M, Rogozin, E, Oren, NC, Keske, Ş, Barchad, OW, Nesher, L. An international multicenter study comparing COVID-19 omicron outcomes in patients with hematological malignancies treated with obinutuzumab versus rituximab. Cancer medicine 13(3), 2024. e-Pub 2024. PMID: 38400683.
- Khawaja, F, Angelidakis, G, Feldman, A, Ravi, V, Woodman, E, Bhatti, MM, Ariza Heredia, E, Elhajj, P, Spallone, A, Jiang, Y, Chemaly, RF. COVID-19 in cancer patients: The impact of vaccination on outcomes early in the pandemic. Cancer medicine 12(24):22006-22022, 2023. e-Pub 2023. PMID: 38063366.
- Dib RW, Spallone A, Khawaja F, Chemaly RF. The Impact of the COVID-19 Pandemic on Hospital-Acquired Infections at A Comprehensive Cancer Center. American Journal of Infection Control 51(12):1302-1308, 2023. e-Pub 2023. PMID: 37804272.
- Khawaja F, Srinivasan K, Spallone A, Feldman A, Cantu S, Ariza-Heredia E, Dvordak T, Alousi A, Ahmed S, George M, Frenzel E, Bhatti M, Chemaly RF. Nosocomial COVID-19 at a comprehensive cancer center during the first year of the pandemic: Lessons learned. Am J Infect Control 51(5):506-513, 2023. e-Pub 2023. PMID: 35901993.
- Khawaja F, Prakash R, Sassine J, Handley G, VanWieren T, Angelidakis G, Iyer SP, Ramdial JL, Ahmed S, Nieto Y, Spallone A, Ariza-Heredia EJ, Chemaly R. Cytomegalovirus (CMV) Reactivation within in the First Year after Chimeric Antigen Receptor (CAR) T Cell Therapy: Experience from the First Two Years at a Major Cancer Center. Blood 140(1):7533-7535, 2022. e-Pub 2022.
- Spallone A, Alotaibi AS, Jiang Y, Daver N, Kontoyiannis DP. Infectious Complications Among Patients With AML Treated With Immune Checkpoint Inhibitors. Clin Lymphoma Myeloma Leuk 22(5):305-310, 2022. e-Pub 2022. PMID: 34810120.
- Spallone A, Moran CA, Wurster S, Axell-House DB, Kontoyiannis DP. Taking a Closer Look: Clinical and Histopathological Characteristics of Culture-Positive versus Culture-Negative Pulmonary Mucormycosis. J Fungi (Basel) 8(4), 2022. e-Pub 2022. PMID: 35448611.
- Spallone A, Hicklen RS, Kontoyiannis DP. Invasive Fungal Infections at Presentation of Untreated Hematologic Malignancies: Rare and Elusive. Open Forum Infect Dis 7(7):ofaa247, 2020. e-Pub 2020. PMID: 32704512.
- Malek AE, Taremi M, Spallone A, Alvarez-Cardona JJ, Kontoyiannis DP. Necrotizing soft tissue invasive aspergillosis in a cancer patient treated with immunosupressants due to checkpoint inhibitor-induced hepatitis. J Infect 80(2):232-254, 2020. e-Pub 2020. PMID: 31705917.
- Spallone A, Woroch L, Sweeney K, Seidman R, Marcos LA. The Burden of Neurocysticercosis at a Single New York Hospital. J Pathog 2020:8174240, 2020. e-Pub 2020. PMID: 32802516.
- Atkinson T, Mahatme S, Spallone A, Fundin J. The Preliminary Impact of Pain Management Integration into an HIV Specialty Clinic. The Scientific Pages of Anesthesia and Pain Management 1(1):7-12, 2017. e-Pub 2017.
- Spallone, A, Tobin, E, Chaturvedi, S, Qian, J. Central Nervous System Blastomycosis Without Travel to Known Endemic Area. Infectious Diseases in Clinical Practice 24(5):e30-e32, 2016. e-Pub 2016.
Invited Articles
- Ford, ES, Papanicolaou, GA, Dadwal, SS, Pergam, SA, Spallone, A. Frequently Asked Questions about Mpox (Formerly Monkeypox Disease) for Hematopoietic Cell Transplantation and Chimeric Antigen Receptor T Cell Recipients from the American Society for Transplantation and Cellular Therapy. Transplantation and Cellular Therapy 29(5):289-292, 2023. e-Pub 2023. PMID: 36746374.
- Spallone A, Schwartz IS. Emerging Fungal Infections. Infect Dis Clin North Am 35(2):261-277, 2021. e-Pub 2021. PMID: 34016278.
Review Articles
- Dib, RW, Ariza Heredia, E, Spallone, A, Chemaly, RF. Respiratory Viral Infections in Recipients of Cellular Therapies. Open Forum Infectious Diseases 10(4), 2023. e-Pub 2023. PMID: 37065990.
- Khawaja F, Daher M, Spallone A, Chemaly RF. COVID-19 Vaccination in Patients With Cancer and Recipients of Cellular Therapy. Oncology (Williston Park) 37(2):69-77, 2023. e-Pub 2023. PMID: 36862845.
- Khawaja F, Spallone A, Kotton CN, Chemaly RF. Cytomegalovirus infection in transplant recipients: Newly approved additions to our armamentarium. Clin Microbiol Infect 29(1):44-50, 2023. e-Pub 2023. PMID: 35843567.
- Spallone, A, Hemmersbach-Miller, M. The Great Masquerade: Donor-derived Infections with Uncommon Central Nervous System Pathogens. OBM Transplantation 5(2), 2021. e-Pub 2021.
- Amenta EM, Spallone A, Rodriguez-Barradas MC, El Sahly HM, Atmar RL, Kulkarni PA. Postacute COVID-19: An Overview and Approach to Classification. Open Forum Infect Dis 7(12):ofaa509, 2020. e-Pub 2020. PMID: 33403218.
- Spallone, A, Dhal, U, Woc-Colburn, L, Hemmersbach-Miller, M. Histoplasmosis in Liver Transplant Recipients: Case Reports and a Review of the Literature. OBM Transplantation 4(1), 2020. e-Pub 2020.
Professional Educational Materials
- Spallone A, Kontoyiannis DP. Skin lesions in a patient with acute myeloid leukemia presenting with febrile neutropenia, 2019.
Editorials
- Spallone A, Ariza-Heredia EJ, Chemaly RF. Acute and Latent Viral Infections in Immunocompromised Patients: A Tale of Brave Battles and Menacing Foes. Clin Microbiol Infect 28(10):1319-1320, 2022. PMID: 35724870.
Abstracts
- Shafat T, Khawaja F, Jackson J, Chemaly RF, Spallone A. Shifting Trend in Outcomes of Respiratory Viral Infections Among Hematopoietic Cell Transplant and Cellular Therapy Recipients during 2023-2024 Respiratory Viral Season. ASTCT 2025, 2025. e-Pub 2025.
- Makhoul J, Jetty S, Khawaja F, Patel K, Lee HC, Horowitz S, Spallone A, Ariza Heredia E, Chemaly RF. Cytomegalovirus Infections in Patients with Relapsed/Refractory Multiple Myeloma on Novel T-Cell Redirecting Therapy. IDWeek 2024 12, 2025. e-Pub 2025.
- Shafat T, LaCombe R, Yaghi L, Angelidakis G, Spallone A, Ariza Heredia E, Hanna GS, Khawaja F, Chemaly RF. Evaluation of a Meta-Virus Signature as a Diagnostic Tool to Predict the Severity of Respiratory Viral Infections in Hematopoietic Cell Transplant Recipients. IDWeek 2024 12, 2025. e-Pub 2025.
- Gaulin C, Chemaly RF, Jiang Y, Ramdial J, Ahmed S, Rondon G, Ariza Heredia E, Spallone A, Iyer S, Kebriaei P, Srour S, Shpall E, Nastoupil L, Khawaja F. Incidence and Risk Factors for Fungal Infection after CD19-targeted Chimeric Antigen Receptor T cell Therapy for Non-Hodgkin Lymphoma. IDWeek 2024 12(1), 2025. e-Pub 2025.
- Daher M, Khawaja F, Spallone A, Shigle TL, Ariza Heredia E, Bhatti MM, Chemaly RF. Real-World Experience with Maribavir for the Treatment of Cytomegalovirus Infection in Patients with Hematologic Malignancies. IDWeek 2024, 2025. e-Pub 2025.
- Angelidakis G, Shafat T, Yaghi L, Khawaja F, Pignataro Oshiro F, Kirsch JM, Ariza Heredia E, Batista M, Gollob KJ, Duerkop BA, Chemaly RF, Spallone A. Outcomes of respiratory viral infections in hematopoietic cell transplant recipients and patients with leukemia: a prospective study. IDWeek 2024 12, 2025. e-Pub 2025.
- Shafat T, Khawaja F, Angelidakis G, Yaghi L, Spallone A, Ariza Heredia E, Chemaly RF. Prognostic Value of the Immunodeficiency Scoring Index for Respiratory Viral Infections in Hematopoietic Cell Transplant Recipients. IDWeek 2024 12, 2025. e-Pub 2025.
- Shafat T, De-la-Rosa-Martinez D, Khawaja F, Jiang Y, Spallone A, Batista M, Ariza Heredia E, Vilar-Compte D, Chemaly RF. Risk Factors for Severe Influenza and Respiratory Syncytial Virus Infections in Patients with Lymphoma or Multiple Myeloma - A Seven-Year Retrospective Cohort Study. IDWeek 2024 12, 2025. e-Pub 2025.
- Jetty S, Makhoul J, Khawaja F, Lee HC, Patel K, Horowitz S, Ariza Heredia E, Spallone A, Chemaly RF. Infectious Complications in Patients with Relapsed/Refractory Multiple Myeloma Undergoing Novel Bispecific Antibody Therapy: A Myeloma-Infectious Disease Database Initiative. IDWeek 2024, 2025. e-Pub 2025.
- Kim Nguyen, Spallone A, Holly Ayers, Mymimilami Santos, Maryam Zaghian, Karim Samir Abdeldaem, Adriana Wechsler. Reducing Blood Culture Contamination in Adult Patients with Cancer Presenting to the Emergency Department. SHEA 2024, 2024. e-Pub 2024.
- Chin-Ting Wu, Spallone A, Sherry Cantu, Todd Treangen, William Shropshire, Micah Bhatti, Israel Glover, Xiaojun Liu, Samuel Shelburne, Awdhesh Kalia. Rapid Genomic Characterization of High-Risk, Antibiotic Resistant Pathogens Using Long-Read Sequencing to Identify Nosocomial Outbreaks. SHEA 2024, 2024. e-Pub 2024.
- Layale Yaghi, PhD, Rita Wilson-Dib, MD, Sherry Cantu, MPH, Piyali Chatterjee, PhD, Chetan Jinadatha, MD, PhD, Roy Chemaly, MD, Spallone A. The efficacy of a filtered handheld far-ultraviolet disinfection device in reducing environmental pathogens from high-touch clinical surfaces in healthcare setting. SHEA 2024, 2024. e-Pub 2024.
- Adina Feldman, Sherry Cantu, Hilary McMurry, Crystal Odom, Leila Nahavandi, Jane Powell, Spallone A. Improving Data Quality from a Hematology Unit Hand Hygiene Observation Program. SHEA 2024, 2024. e-Pub 2024.
- Sherry Cantu, Spallone A, Roy Chemaly, Jane Elizabeth Powell, Ha Bui, Nadeem Prasla. Automated Discontinuation of Isolation Precautions with the Use of Electronic Health Record Tools. SHEA 2024, 2024. e-Pub 2024.
- Feldman A, Bhatti M, Powell J, Chemaly RF, Spallone A. Prevalence of Candida auris Among High-Risk Patients at a Comprehensive Cancer Center. SHEA 2024, 2024. e-Pub 2024.
- Febres-Aldana AJ, Khawaja F, Spallone A, Srinivasan K, Shigle TL, Morado Aramburo O, Rondon G, Ramdial J, Shpall E, Ariza Heredia E, Chemaly RF, Sassine J. Duration of letermovir primary prophylaxis in hematopoietic cell transplant recipients at high risk for cytomegalovirus infections and impact on outcomes, Open Forum Infectious Diseases, Volume 10, Issue. IDWeek 2023, 2023. e-Pub 2023.
- Shafat T, Spallone A, Chemaly RF, Nesher L. International Multi-Center Study Comparing the Effect of Obinutuzumab or Rituximab Treatment in Hematological Patients on COVID-19 Outcomes During the Omicron Surge. IDWeek 2023, 2023. e-Pub 2023.
- Khawaja F, Sassine J, Handley G, Prakash R, Angelidakis G, Ahmed S, Ramdial JL, Nieto Y, Rondon G, Ariza-Heredia EJ, Spallone A, Iyer SP, Chemaly RF. Human Herpes Virus 6 Dnaemia within 1 Year of Chimeric Antigen Receptor T Cell Therapy. ASTCT 2023, 2023. e-Pub 2023.
- Morado Aramburo O, Spallone A, Khawaja F, Sassine J, Srinivasan K, Febres-Aldana AJ, Shigle TL, Rondon G, Ramdial J, Shpall E, Ariza-Heredia E, Chemaly RF. The Impact of Donor CMV Serostatus on Outcomes of CMV Infections in the Era of Letermovir. IDWeek 2022, 2022. e-Pub 2022.
- Wilson Dib R, Spallone A, Khawaja F, Roy F Chemaly. Characteristics of Hospital Onset SARS Cov-2 Infections Before and After the Emergence of The Highly Transmissible Variant B. 1.1. 529 In a Comprehensive Cancer Center. IDWeek 2022, 2022. e-Pub 2022.
- Bergin SP, Chemaly RF, Duttagupta R, Bigelow R, Dadwal SS, Hill JA, Lee YJ, Haidar G, Luk A, Drelick AC, Chin-Hong PV, Benamu E, Davis T, Wolf O, McClain MT, Maziarz EK, Madut D, Bedoya A, Gilstrap DL, Todd J, Barkauskas C, Puing A, Spallone A, McDowell BJ, Shariff D, Salsgiver E, Nanayakkara DD, Khawaja F, Papanicolaou G, Spagnoletti J, English M, Fung M, Russel P, Ibrahimi S, Pandey S, Adams S, Liang W, Nemirovich-Danchenko E, Mughar M, Dalai S, Cho Y, Ahmed AA, Hollemon D, Hong DK, Vaughn ML, Blauwkamp T, Vucetic Z, Romano R, Fowler VG, Holland TL. PICKUP: Pneumonia in the Immunocompromised - Use of the Karius Test for Detection of Undiagnosed Pathogens. IDWeek 2022 9(Supplemement 2), 2022. e-Pub 2022.
- Wilson Dib R, Spallone A, Khawaja F, Chemaly RF. The Impact of the COVID-19 Pandemic on Hospital-Acquired Infections at a Comprehensive Cancer Center. IDWeek 2022, 2022. e-Pub 2022.
- Srinivasan K, Spallone A, Khawaja F, Sassine J, Morado Aramburo O, Febres-Aldana AJ, Rondon G, Ramdial J, Shpall E, Ariza-Heredia E, Chemaly RF. The Impact of HHV-6 DNAemia on hematopoietic cell transplant (HCT) recipients at high risk for CMV reactivation in the era of Letermovir. InOpen Forum Infectious Diseases 2022 Dec 1 (Vol. 9, No. Supplement_2, pp. ofac492-1743). US: Oxford University Press. IDWeek 2022, 2022. e-Pub 2022.
- Daher M, Khawaja F, Angelidakis G, Rondon G, Spallone A, Ramdial J, Ariza-Heredia E, Shpal E, Chemaly RF. Predictive Value of the Immunodeficiency Scoring Index for COVID-19 Related Outcomes in Hematopoietic Transplant Recipients. IDWeek 2022, 2022. e-Pub 2022.
- Febres-Aldana A, Spallone A, Khawaja F, Chemaly RF. Long term hematopoietic cell transplant outcomes in patients at high risk for cytomegalovirus infections in the era of letermovir. InOpen Forum Infectious Diseases 2022 Dec 1 (Vol. 9, No. Supplement_2, pp. ofac492-112). US: Oxford University Press. IDWeek 2022, 2022. e-Pub 2022.
- Fareed Khawaja, Rishab Prakash, Joseph Sassine, Guy Handley, Tracy VanWieren, Georgios Angelidakis, Swaminathan P. Iyer, Jeremy L. Ramdial, Sairah Ahmedy, Yago Nieto, Ella J. Ariza-Heredia, Spallone A, Roy Chemaly. Cytomegalovirus (CMV) Reactivation within in the First Year after Chimeric Antigen Receptor (CAR) T Cell Therapy: Experience from the First Two Years at a Major Cancer Center. ASTCT 2022, 2022. e-Pub 2022.
- Spallone A, Khawaja F, Ariza-Heredia E, Papanicolaou GA, Boeckh MJ, Dadwal SS, Abidi MZ, Camargo JF, El Boghdadly Z, Shahid Z, Chemaly RF. Transplant Providers’ Perceptions of COVID-19 Vaccination in the Wake of a Global Pandemic. ASTCT 2022, 2022. e-Pub 2022.
- Khawaja F, Sassine J, Handley G, Iyer SP, Ramdial J, Ahmed S, Nieto Y, Spallone A, Ariza-Heredia EJ, Chemaly RF. Herpesviruses Infections in CAR T Cell Recipients. ASTCT 2022, 2022. e-Pub 2022.
- Sassine J, Khawaja F, Shank BR, Lovell A, Lee J, DiPippo A, Rausch CR, Spallone A, Ariza Heredia E, Chemaly RF. Clinically Significant CMV Infections in Patients with Lymphoma or Multiple Myeloma. IDWeek 2021, 2021. e-Pub 2021.
- Spallone A, Srinivasan K, Sassine J, Shigle TL, Handy V, Ramdial J, Khawaja F, Ariza Heredia E, Chemaly RF. The Impact of Clinically Significant CMV Infections on Other Viral Infections in the Era of Letermovir Primary Prophylaxis. IDWeek 2021, 2021. e-Pub 2021.
- Franklin A, Axell-House DB, Spallone A, Tarrand J, Kontoyiannis DP. Comparison of Initial CXR to CT in Patients (pts) with Hematologic Malignancy (HEM) and Documented Symptomatic Pulmonary Mucormycosis (PM). IDWeek 2021 8(1):S454,, 2021. e-Pub 2021.
- Khoo T, Spallone A, Lier A, Abul Y, Wellins A, Weinbaum F, Luft B, Marcos AL. Lyme Disease in Hispanics in Long Island, New York: A New Health Disparity in the U.S. IDWeek 2017 4(1):S308, 2017. e-Pub 2017.
- Khoo T, Fleischner Z, Spallone A, Chow R, Monteforte M, Marcos AL. Comparison of Fidaxomicin and Vancomycin for Recurrent Clostridium difficile Colitis. IDWeek 2017 4(1):S386, 2017. e-Pub 2017.
- Abul Y, Chow R, Spallone A, Luft B, Marcos LA. Epidemiology of Lyme Disease in Hispanics Admitted to a Tertiary Medical Center in Long Island. IDWeek 2016 3(1):1422, 2016. e-Pub 2016.
- Spallone A, Chow R, Marcos LA. Epidemiology of Neurocysticercosis at Stony Brook University Hospital, Long Island, New York. IDWeek 2016 3(1):584, 2016. e-Pub 2016.
- Daher M, Spallone A. Risk Factors and Outcomes of Resistant CMV Infections in Hematopoietic Cell Transplant Recipients: a 7-Year Review. IDWeek 2025.
- Sherry Cantu, MPH, Ha Bui,, Nadeem Prasla, Roy F Chemaly, MD, MPH,, Jane Powell, DNP, Spallone A. Automated Discontinuation of Isolation Precautions with the Use of Electronic Health Record Tools. 2024 Division of Internal Medicine Research Retreat & Poster Session.
- Adina Feldman, MPH,, Micah Bhatti, MD, PhD,, Jane Powell, DNP,, Roy Chemaly, MD, MPH, Spallone A. Prevalence of Candida auris Among High-Risk Patients at a Comprehensive Cancer Center. 2024 Division of Internal Medicine Research Retreat & Poster Session.
- Borjan J, Wu CT, Young A, Yaghi L, Bhatti MM, Vuong NN, Handley G, Spallone A, Shelburne S, Shropshire WC. A Preponderance of Ceftazidime-Avibactam Resistance in Escherichia coli Driven by NDM-5 β-lactamases at a Large US Cancer Center. 8th Annual TMC Antimicrobial Resistance Research and Stewardship Conference.
- Lee YJ, Shafat T, Li Y, Shah GL, Spallone A, Obeid K, Djoverti V, Hammond SP, Young JH, Hill JA, Chemaly RF, Papanicolaou GA. Burden of acyclovir resistant mucocutaneous human herpes simplex virus infection post hematopoietic cell transplantation: A multicenter US study. EBMT 2025.
- Makhoul J, Jetty S, Khawaja F, Patel K, Lee H, Sheeba T, Gesini L, Morales de Partovi C, Seif S, Horowitz S, Spallone A, Ariza Heredia A, Chemaly RF. Cytomegalovirus infections in patients with relapsed/refractory multiple myeloma on novel therapies. ECCMID 2025.
- Spallone A, Shafat T, Lopez V, Jackson J, Angelidakis G, Chemaly RF. Outcomes of Respiratory Syncytial Virus Infections among Cancer Patients During the Two Recent Respiratory Viral Seasons (2022-2024). ECCMID 2025.
- Feldman A, Cantu S, Powell J, Poths R, Handley G, Spallone A. Setting the Standard: Developing a High-Consequence Infectious Disease Preparedness Policy for a Comprehensive Cancer Hospital. SHEA 2025.
- Wu CT, Handley G, Shropshire W, Cantu S, Powell JE, Bhatti MM, Shelburne S, Spallone A. Using Oxford Nanopore Sequencing to Investigate Potential Plasmid Transmission of the blaNDM-5 Gene. SHEA 2025.
- Feldman A, Cantu S, Bhatti M, Powell J, Poths R, Handley G, Spallone A. Implementing a Candida auris Screening Program at a Comprehensive Cancer Center. SHEA 2025.
- Shafat T, Khawaja F, Jackson J, Chemaly RF, Spallone A. Shifting Trends in Respiratory Viral Infection Outcomes Among Patients with Hematology Malignancies During 2023-2024 Respiratory Viral Season. 5th Symposium on Infectious Diseases in the Immunocompromised Host.
- Borjan J, Bhatti MM, Vuong N, Handley G, Spallone A. Blood Culture Stewardship Efforts at a Comprehensive Cancer Center Reduced Isolation of Skin Flora Contaminants Without Compromising Patient Care. IDWeek 2025.
- Vuong NN, Spallone A. Characterization of Beta-lactam Allergies and Impact on Antibiotic Selection in the Immunocompromised Population at a Large Comprehensive Cancer Hospital. IDWeek 2025.
- Vuong NN, Chung J, Dai J, Borjan J, Dailey Garnes N, Spallone A, Handley G. Assessing Documented Beta-lactam Allergies at a Large Comprehensive Cancer Hospital. IDWeek 2025.
- Ohashi Y, Chemaly RF, Khawaja F, Daher M, Spallone A, Shafat T, Ariza-Heredia EJ, Handley G. Factors Associated with Human Herpesvirus 6 DNAemia Among Allogeneic Hematopoietic Cell Transplant Recipients in the Modern Era.
- Rita Wilson Dib, Adrienne Gonzales, Spallone A, Victor Mulanovich. Relapsing Pseudomonas aeruginoa bacteremia: Where did it come from?. ECCMID 2023.
- Spallone A, Rita Wilson Dib, MD, Fareed Khawaja, MBBS, Roy F Chemaly, MD, MPH. Hospital-acquired infections on the COVID-19 units at a comprehensive cancer centre. ECCMID 2023.
- Chin-Ting Wu, William Shropshire,, Micah M Bhatti,, Sherry Cantu,, Israel K Glover,, Xiaojun Liu,, Awdhesh Kalia,, Todd Treangen,, Samuel Shelburne, Spallone A. Rapid Genomic Characterization of High-Risk Pathogens Using Long-Read Sequencing to Identify Nosocomial Outbreaks. Nanopore Community Meeting.
- Chin-Ting Wu, William Shropshire, Micah M Bhatti, Sherry Cantu, Israel K Glover, Xiaojun Liu, Awdhesh Kalia, Todd Treangen, Samuel Shelburne, Spallone A. Rapid Genomic Characterization of High-Risk Pathogens Using Long-Read Sequencing to Identify Nosocomial Outbreaks. 7th Annual Texas Medical Center AMR & Stewardship Conference.
- Layale Yaghi, PhD, Rita Wilson-Dib, MD, Sherry Cantu, MPH, Piyali Chatterjee, PhD, Chetan Jinadatha, MD, PhD, Roy Chemaly, MD, MPH, Spallone A. The efficacy of a filtered handheld far-ultraviolet disinfection device in reducing environmental pathogens from high-touch clinical surfaces in healthcare setting. ICHS 2024.
- Layale Yaghi, PhD, Rita Wilson-Dib, MD, Sherry Cantu, MPH, Piyali Chatterjee, PhD, Chetan Jinadatha, MD, PhD, Roy Chemaly, MD, MPH, Spallone A. The efficacy of a filtered handheld far-ultraviolet disinfection device in reducing environmental pathogens from high-touch clinical surfaces in healthcare setting. ECCMID 2024.
- Chin-Ting Wu, William Shropshire,, Micah M Bhatti,, Sherry Cantu,, Israel K Glover,, Xiaojun Liu,, Awdhesh Kalia,, Todd Treangen,, Samuel Shelburne, Spallone A. Rapid Genomic Characterization of High-Risk Pathogens Using Long-Read Sequencing to Identify Nosocomial Outbreaks. The Division of Pathology and Laboratory Medicine DPLM Annual Research Day.
- Spallone A, Khawaja F, Ariza-Heredia E,, Papanicolaou GA,, Boeckh MJ,, Dadwal SS,, Abidi MZ,, Camargo JF,, El Boghdadly Z,, Shahid Z,, Chemaly RF. Transplant Providers’ Perceptions of COVID-19 Vaccination in the Wake of a Global Pandemic. ECCMID 2022.
- Spallone A, Rita Wilson Dib, MD, Fareed Khawaja, MBBS, Roy F Chemaly, MD, MPH. The impact of the COVID-19 pandemic on hospital-acquired infections at a comprehensive cancer center. ICHS 2022.
- Spallone A, Rita Wilson Dib, MD, Fareed Khawaja, MBBS, Roy F Chemaly, MD, MPH. Hospital onset SARS CoV-2 infections before and after the emergence of the highly transmissible variant B.1.1.529 in a comprehensive cancer center. ICHS 2022.
- Fareed Khawaja, Carmen Sadaka,, Samantha Trager,, Kerri Fernandes,, Ella J. Ariza-Heredia, Spallone A, Michelle Altrich,, Roy F. Chemaly. The use of a commercially available CMV T Cell Immunity Panel to Assess the Risk of CMV Infections in Hematopoietic Cell Transplant Recipients with Low Level CMV Viremia. ICHS 2022.
Book Chapters
- Franklin, A, Spallone, A, Chemaly, RF. Cytomegalovirus Diseases in Hematopoietic Cell Transplant Recipients. In: Pulmonary and Critical Care Considerations of Hematopoietic Stem Cell Transplantation. Springer International Publishing, 141-160, 2024.
- Amy Spallone, Daniel Musher. Haemophilus influenzae. In: Schlossberg's Clinical Infectious Disease. 3rd. Oxford University Press, 931-935, 2022.
- Spallone A, Woc-Colburn L. Mycoses. In: Case Files: Microbiology. 4th. McGraw-Hill.
Books (edited and written)
- Roy Chemaly, Steve Pergam, Spallone A. Infection Control in Immunocompromised Patients. Springer.
Patient Reviews
CV information above last modified August 17, 2025