Anastasios Maniakas, M.D., Ph.D., FRCSC
Department of Head and Neck Surgery, Division of Surgery
About Dr. Anastasios Maniakas
Anastasios Maniakas, M.D., PhD., is an Assistant Professor in the Department of Head and Neck Surgery at The University of Texas MD Anderson Cancer Center. Dr. Maniakas received his undergraduate, master’s, and doctoral degrees from McGill University, and his medical doctorate from the University of Montreal. He completed his residency at the University of Montreal followed by a fellowship in head and neck surgical oncology at The University of Texas MD Anderson Cancer Center. His clinical expertise is in head and neck cancers, with an emphasis on thyroid and parathyroid disease, oral cavity cancer, skin cancers, and salivary gland neoplasms. Dr. Maniakas’ research interests focus on translational research, with the goal to identify and develop novel head and neck cancer treatments and lead pre-clinical and multi-phase clinical trials.
Present Title & Affiliation
Primary Appointment
Assistant Professor, Department of Head and Neck Surgery, Division of Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX
Education & Training
Degree-Granting Education
| 2022 | McGill University, Montreal, CAN, PHD, Experimental Surgery |
| 2018 | McGill University, Montreal, CAN, MSc, Experimental Surgery |
| 2013 | University of Montreal, Montreal, CAN, MD, Medical Doctorate |
| 2009 | McGill University, Montreal, CAN, BSc, Microbiology & Immunology, Minor in Classical Studies |
Postgraduate Training
| 2019-2020 | Research Fellowship, Head and Neck Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX |
| 2018-2019 | Clinical Fellowship, Head and Neck Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX |
| 2014-2015 | Global Clinical Scholars Research Training Program, Harvard Medical School, Boston, MA |
| 2013-2018 | Clinical Residency, Otolaryngology - Head & Neck Surgery, University of Montreal, Montreal |
Board Certifications
| 2020 | Royal College of Physicians and Surgeons of Canada |
Experience & Service
Academic Appointments
Assistant Professor, Department of Surgery, Division of Otolaryngology-Head and Neck Surgery, University of Montreal - Hopital Maisonneuve-Rosemont, Montreal, 2020 - 2021
Honors & Awards
| 2019 | CIHR Vanier CGS Doctoral Award, Canadian Institutes of Health Research |
| 2018 | Daniel-Tasse Award Department of Surgery, University of Montreal |
| 2018 | Junior Fellowship Award, European Rhinologic Society |
| 2017 | Detweiler Fellowship Award, Royal College of Canada |
| 2015 | Harvard Medical School - Distinction, Harvard Medical School |
| 2015 | Frederick Banting and Charles Best CGS-M, Canadian Institutes of Health Research |
| 2015 | Master's Degree Award, FRQS |
| 2009 | McGill University Academy of Athens Prize, McGill University |
Professional Memberships
Selected Publications
Peer-Reviewed Articles
- Lampasona G, Berdugo J, Noujaim J, Gologan O, Maniakas A.. Locoregionally Advanced, BRAF V600L-Positive, Mucosal Melanoma of the Hypopharynx Treated With a Combination of BRAF and MEK Inhibitors. Journal of Clinical Oncology - Precision Oncology, 2022. PMID: 35709404.
- Maniakas A, Zafereo M, Cabanillas ME.. Anaplastic Thyroid Cancer: New Horizons and Challenges. Updates in Thyroidology - Endocrinology and Metabolism Clinics of North America 51(2):391-401, 2022. PMID: 35662448.
- Zagury-Orly I, Khaouam N, Noujaim J, Desrosiers MY, Maniakas A. The Effect of Radiation and Chemoradiation Therapy on the Head and Neck Mucosal Microbiome: A Review. Front Oncol 11:5068, 2021. e-Pub 2021. PMID: 34926301.
- Maniakas A, Henderson YC, Hei H, Peng S, Chen Y, Jiang Y, Ji S, Cardenas M, Chiu Y, Bell D, Williams MD, Hofmann MC, Scherer SE, Wheeler DA, Busaidy NL, Dadu R, Wang JR, Cabanillas ME, Zafereo M, Johnson FM, Lai SY. Novel Anaplastic Thyroid Cancer PDXs and Cell Lines: Expanding Preclinical Models of Genetic Diversity. J Clin Endocrinol Metab 106(11):e4652-e4665, 2021. PMID: 34147031.
- Henderson YC, Mohamed ASR, Maniakas A, Chen Y, Powell RT, Peng S, Cardenas M, Williams MD, Bell D, Zafereo ME, Wang RJ, Scherer SE, Wheeler DA, Cabanillas ME, Hofmann MC, Johnson FM, Stephan CC, Sandulache V, Lai SY. A High-throughput Approach to Identify Effective Systemic Agents for the Treatment of Anaplastic Thyroid Carcinoma. J Clin Endocrinol Metab 106(10):2962-2978, 2021. PMID: 34120183.
- Chen Y, Maniakas A, Tan L, Cui M, Le X, Niedzielski JS, Michel KA, Harlan CJ, Lu W, Henderson YC, Mohamed ASR, Lorenzi PL, Putluri N, Bankson JA, Sandulache VC, Lai SY. Development of a rational strategy for integration of lactate dehydrogenase A suppression into therapeutic algorithms for head and neck cancer. Br J Cancer 124(10):1670-1679, 2021. e-Pub 2021. PMID: 33742144.
- Maniakas A, Asmar MH, Renteria AE, Nayan S, Alromaih S, Endam LM, Sampalis JS, Desrosiers M. Azithromycin in high-risk, refractory chronic rhinosinusitus after endoscopic sinus surgery and corticosteroid irrigations: a double-blind, randomized, placebo-controlled trial. Int Forum Allergy Rhinol 11(4):747-754, 2021. e-Pub 2020. PMID: 32929891.
- Srivastava A, Maniakas A, Myers J, Chambers MS, Cardoso R. Reconstruction of intraoral oncologic surgical defects with Integra® bilayer wound matrix. Clin Case Rep 9(1):213-219, 2021. e-Pub 2020. PMID: 33489162.
- Maniakas A, Dadu R, Busaidy NL, Wang JR, Ferrarotto R, Lu C, Williams MD, Gunn GB, Hofmann MC, Cote G, Sperling J, Gross ND, Sturgis EM, Goepfert RP, Lai SY, Cabanillas ME, Zafereo M. Evaluation of Overall Survival in Patients With Anaplastic Thyroid Carcinoma, 2000-2019. JAMA Oncol 6(9):1397-1404, 2020. PMID: 32761153.
- Maniakas A, Jozaghi Y, Zafereo ME, Sturgis EM, Su SY, Gillenwater AM, Gidley PW, Lewis CM, Diaz E, Goepfert RP, Kupferman ME, Gross ND, Hessel AC, Pytynia KB, Nader ME, Wang JR, Lango MN, Kiong KL, Guo T, Zhao X, Yao CMKL, Appelbaum E, Alpard J, Garcia JA, Terry S, Flynn JE, Bauer S, Fournier D, Burgess CG, Wideman C, Johnston M, You C, De Luna R, Joseph L, Diersing J, Prescott K, Heiberger K, Mugartegui L, Rodriguez J, Zendehdel S, Sellers J, Friddell RA, Thomas A, Khanjae SJ, Schwarzlose KB, Chambers MS, Hofstede TM, Cardoso RC, Wesson RA, Won A, Otun AO, Gombos DS, Al-Zubidi N, Hutcheson KA, Gunn GB, Rosenthal DI, Gillison ML, Ferrarotto R, Weber RS, Hanna EY, Myers JN, Lai SY. Head and neck surgical oncology in the time of a pandemic: Subsite-specific triage guidelines during the COVID-19 pandemic. Head Neck 42(6):1194-1201, 2020. PMID: 32342541.
- Zahedi A, Bondaz L, Rajaraman M, Leslie WD, Jefford C, Young JE, Pathak KA, Bureau Y, Rachinsky I, Badreddine M, De Brabandere S, Fong H, Maniakas A, Van Uum S. Risk for Thyroid Cancer Recurrence Is Higher in Men Than in Women Independent of Disease Stage at Presentation. Thyroid 30(6):871-877, 2020. e-Pub 2019. PMID: 31524071.
- Yang N, Boudoux C, De Montigny E, Maniakas A, Gologan O, Madore WJ, Khullar S, Guertin L, Christopoulos A, Bissada E, Ayad T. Rapid head and neck tissue identification in thyroid and parathyroid surgery using optical coherence tomography. Head Neck 41(12):4171-4180, 2019. e-Pub 2019. PMID: 31571306.
- Maniakas A, Davies L, Zafereo ME. Thyroid Disease Around the World. Otolaryngol Clin North Am 51(3):631-642, 2018. e-Pub 2018. PMID: 29548512.
- Maniakas A, Christopoulos A, Bissada E, Guertin L, Olivier MJ, Malaise J, Ayad T. Perioperative practices in thyroid surgery: An international survey. Head Neck 39(7):1296-1305, 2017. e-Pub 2017. PMID: 28493562.
- Maniakas A, Moubayed SP, Ayad T, Guertin L, Nguyen-Tan PF, Gologan O, Soulieres D, Christopoulos A. North-American survey on HPV-DNA and p16 testing for head and neck squamous cell carcinoma. Oral Oncol 50(10):942-6, 2014. e-Pub 2014. PMID: 25096827.
- Saliba J, Payne RJ, Varshney R, Sela E, Maniakas A, Rahme E, Mlynarek A, Caglar D, Hier MP, Tamilia M. Sentinel Lymph Node Biopsy Status Correlates with Postoperative Stimulated Thyroglobulin Levels in Low-risk Papillary Thyroid Cancer Patients. Endocr Pract 20(5):399-404, 2014. PMID: 24325994.
- Maniakas A, Forest VI, Jozaghi Y, Saliba J, Hier MP, Mlynarek A, Tamilia M, Payne RJ. Tumor classification in well-differentiated thyroid carcinoma and sentinel lymph node biopsy outcomes: a direct correlation. Thyroid 24(4):671-4, 2014. e-Pub 2014. PMID: 24199963.
Book Chapters
- Maniakas A, Davies L, Zafereo M.. Thyroid Disease around the world. In: Global Health in Otolaryngology: Otolaryngologic Clinics of North America. Elsevier, 2018.
- Maniakas A, Christopoulos A. Cancer of the cervical esophagus. In: Eugene Myers Operative Otolaryngology - Head and Neck Surgery. 3. Elsevier, 2017.