Andrew G Sikora, M.D., Ph.D.

Peer-Reviewed Articles

1. Gupta R, Rady PL, Sikora AG, Tyring SK. The role of human papillomavirus in the pathogenesis of sinonasal inverted papilloma: a narrative review. Rev Med Virol 31(3):e2178, 2021. e-Pub 2020. PMID: 33048407.
2. Gelbard A, Wanjalla C, Wootten CT, Drake WP, Lowery AS, Wheeler DA, Cardenas MF, Sikora AG, Pathak RR, McDonnell W, Mallal S, Pilkinton M. The Proximal Airway Is a Reservoir for Adaptive Immunologic Memory in Idiopathic Subglottic Stenosis. Laryngoscope 131(3):610-617, 2021. e-Pub 2020. PMID: 32603507.
3. Mazul AL, Hartman C, Kramer J, White DL, Royse K, Raychaudhury S, Sandulache V, Ahmed ST, Richardson P, Sikora AG, Chiao E. Incidence and survival for oropharynx and non-oropharynx head and neck cancers among veterans living with HIV. Cancer Med 9(24):9326-9335, 2020. e-Pub 2020. PMID: 33094910.
4. Uzunparmak B, Gao M, Lindemann A, Erikson K, Wang L, Lin E, Frank SJ, Gleber-Netto FO, Zhao M, Skinner HD, Newton J, Sikora AG, Myers JN, Pickering CR. Caspase 8 loss radiosensitizes head and neck squamous cell carcinoma to SMAC mimetic induced necroptosis. JCI Insight 5(23), 2020. e-Pub 2020. PMID: 33108350.
5. Mullany LK, Rohira AD, Leach JP, Kim JH, Monroe TO, Ortiz AR, Stork B, Gaber MW, Sarkar P, Sikora AG, Rosengart TK, York B, Song Y, Dacso CC, Lonard DM, Martin JF, O'Malley BW. A steroid receptor coactivator stimulator (MCB-613) attenuates adverse remodeling after myocardial infarction. Proc Natl Acad Sci U S A 117(49):31353-31364, 2020. e-Pub 2020. PMID: 33229578.
6. Vantaku V, Putluri V, Bader DA, Maity S, Ma J, Arnold JM, Rajapakshe K, Donepudi SR, von Rundstedt FC, Devarakonda V, Dubrulle J, Karanam B, McGuire SE, Stossi F, Jain AK, Coarfa C, Cao Q, Sikora AG, Villanueva H, Kavuri SM, Lotan Y, Sreekumar A, Putluri N. Epigenetic loss of AOX1 expression via EZH2 leads to metabolic deregulations and promotes bladder cancer progression. Oncogene 39(40):6265-6285, 2020. e-Pub 2019. PMID: 31383940.
7. Paez-Mayorga J, Capuani S, Hernandez N, Farina M, Chua CYX, Blanchard R, Sizovs A, Liu HC, Fraga DW, Niles JA, Salazar HF, Corradetti B, Sikora AG, Kloc M, Li XC, Gaber AO, Nichols JE, Grattoni A. Neovascularized implantable cell homing encapsulation platform with tunable local immunosuppressant delivery for allogeneic cell transplantation. Biomaterials 257:120232, 2020. e-Pub 2020. PMID: 32768727.
8. Vantaku V, Putluri V, Bader DA, Maity S, Ma J, Arnold JM, Rajapakshe K, Donepudi SR, von Rundstedt FC, Devarakonda V, Dubrulle J, Karanam B, McGuire SE, Stossi F, Jain AK, Coarfa C, Cao Q, Sikora AG, Villanueva H, Kavuri SM, Lotan Y, Sreekumar A, Putluri N. Correction: Epigenetic loss of AOX1 expression via EZH2 leads to metabolic deregulations and promotes bladder cancer progression. Oncogene 39(40):6387-6392, 2020. PMID: 32820250.
9. Elhalawani H, Mohamed ASR, Elgohari B, Lin TA, Sikora AG, Lai SY, Abusaif A, Phan J, Morrison WH, Gunn GB, Rosenthal DI, Garden AS, Fuller CD, Sandulache VC. Tobacco exposure as a major modifier of oncologic outcomes in human papillomavirus (HPV) associated oropharyngeal squamous cell carcinoma. BMC Cancer 20(1):912, 2020. e-Pub 2020. PMID: 32967643.
10. Ferrarotto R, Bell D, Rubin ML, Hutcheson KA, Johnson JM, Goepfert RP, Phan J, Elamin YY, Torman DK, Warneke CL, Hessel AC, Garden AS, Myers JN, Johnson FM, Lee JJ, Sikora AG, Gillison ML, Glisson BS, Gross ND. Impact of Neoadjuvant Durvalumab with or without Tremelimumab on CD8+ Tumor Lymphocyte Density, Safety, and Efficacy in Patients with Oropharynx Cancer: CIAO Trial Results. Clin Cancer Res 26(13):3211-3219, 2020. e-Pub 2020. PMID: 32269052.
11. Krupar R, Watermann C, Idel C, Ribbat-Idel J, Offermann A, Pasternack H, Kirfel J, Sikora AG, Perner S. In silico analysis reveals EP300 as a panCancer inhibitor of anti-tumor immune response via metabolic modulation. Sci Rep 10(1):9389, 2020. e-Pub 2020. PMID: 32523042.
12. Arnold JM, Gu F, Ambati CR, Rasaily U, Ramirez-Pena E, Joseph R, Manikkam M, San Martin R, Charles C, Pan Y, Chatterjee SS, Den Hollander P, Zhang W, Nagi C, Sikora AG, Rowley D, Putluri N, Zhang XH, Karanam B, Mani SA, Sreekumar A. UDP-glucose 6-dehydrogenase regulates hyaluronic acid production and promotes breast cancer progression. Oncogene 39(15):3089-3101, 2020. e-Pub 2019. PMID: 31308490.
13. Arnold JM, Gu F, Ambati CR, Rasaily U, Ramirez-Pena E, Joseph R, Manikkam M, Martin RS, Charles C, Pan Y, Chatterjee SS, Den Hollander P, Zhang W, Nagi C, Sikora AG, Rowley D, Putluri N, Zhang XH, Karanam B, Mani SA, Sreekumar A. Correction: UDP-glucose 6-dehydrogenase regulates hyaluronic acid production and promotes breast cancer progression. Oncogene 39(15):3226-3228, 2020. PMID: 32214199.
14. Frederick M, Skinner HD, Kazi SA, Sikora AG, Sandulache VC. High expression of oxidative phosphorylation genes predicts improved survival in squamous cell carcinomas of the head and neck and lung. Sci Rep 10(1):6380, 2020. e-Pub 2020. PMID: 32286489.
15. Sandulache VC, Lei YL, Heasley LE, Chang M, Amos CI, Sturgis EM, Graboyes E, Chiao EY, Rogus-Pulia N, Lewis J, Madabhushi A, Frederick MJ, Sabichi A, Ittmann M, Yarbrough WG, Chung CH, Ferrarotto R, Mai W, Skinner HD, Duvvuri U, Gerngross P, Sikora AG. Innovations in risk-stratification and treatment of Veterans with oropharynx cancer; roadmap of the 2019 Field Based Meeting. Oral Oncol 102:104440, 2020. e-Pub 2019. PMID: 31648864.
16. Kemnade JO, Elhalawani H, Castro P, Yu J, Lai S, Ittmann M, Mohamed ASR, Lai SY, Fuller CD, Sikora AG, Sandulache VC. CD8 infiltration is associated with disease control and tobacco exposure in intermediate-risk oropharyngeal cancer. Sci Rep 10(1):243, 2020. e-Pub 2020. PMID: 31937831.
17. Pham N, Ludwig MS, Wang M, Ebrahimpour A, Bonnen MD, Diwan AH, Kim SJ, Bryan J, Newton JM, Sikora AG, Donovan DT, Sandulache V, Ghebre YT. Topical Esomeprazole Mitigates Radiation-Induced Dermal Inflammation and Fibrosis. Radiat Res 192(5):473-482, 2019. e-Pub 2019. PMID: 31415221.
18. Montealegre JR, Varier I, Bracamontes CG, Dillon LM, Guillaud M, Sikora AG, Follen M, Adler-Storthz K, Scheurer ME. Racial/ethnic variation in the prevalence of vaccine-related human papillomavirus genotypes. Ethn Health 24(7):804-815, 2019. e-Pub 2017. PMID: 28870103.
19. Gelbard A, Anderson C, Berry LD, Amin MR, Benninger MS, Blumin JH, Bock JM, Bryson PC, Castellanos PF, Chen SC, Clary MS, Cohen SM, Crawley BK, Dailey SH, Daniero JJ, de Alarcon A, Donovan DT, Edell ES, Ekbom DC, Fernandes-Taylor S, Fink DS, Franco RA, Garrett CG, Guardiani EA, Hillel AT, Hoffman HT, Hogikyan ND, Howell RJ, Huang LC, Hussain LK, Johns MM, Kasperbauer JL, Khosla SM, Kinnard C, Kupfer RA, Langerman AJ, Lentz RJ, Lorenz RR, Lott DG, Lowery AS, Makani SS, Maldonado F, Mannion K, Matrka L, McWhorter AJ, Merati AL, Mori MC, Netterville JL, O'Dell K, Ongkasuwan J, Postma GN, Reder LS, Rohde SL, Richardson BE, Rickman OB, Rosen CA, Rutter MJ, Sandhu GS, Schindler JS, Schneider GT, Shah RN, Sikora AG, Sinard RJ, Smith ME, Smith LJ, Soliman AMS, Sveinsdóttir S, Van Daele DJ, Veivers D, Verma SP, Weinberger PM, Weissbrod PA, Wootten CT, Shyr Y, Francis DO. Comparative Treatment Outcomes for Patients With Idiopathic Subglottic Stenosis. JAMA Otolaryngol Head Neck Surg:1-10. e-Pub 2019. PMID: 31670805.
20. Harms A, Kansara S, Stach C, Richardson PA, Chen G, Lai S, Sikora AG, Parke R, Donovan D, Chiao E, Skinner H, Sandulache VC. Swallowing Function in Survivors of Oropharyngeal Cancer Is Associated With Advanced T Classification. Ann Otol Rhinol Laryngol 128(8):696-703, 2019. e-Pub 2019. PMID: 30913911.
21. Newton JM, Hanoteau A, Liu HC, Gaspero A, Parikh F, Gartrell-Corrado RD, Hart TD, Laoui D, Van Ginderachter JA, Dharmaraj N, Spanos WC, Saenger Y, Young S, Sikora AG. Immune microenvironment modulation unmasks therapeutic benefit of radiotherapy and checkpoint inhibition. J Immunother Cancer 7(1):216, 2019. e-Pub 2019. PMID: 31409394.
22. Vantaku V, Dong J, Ambati CR, Perera D, Donepudi SR, Amara CS, Putluri V, Ravi SS, Robertson MJ, Piyarathna DWB, Villanueva M, von Rundstedt FC, Karanam B, Ballester LY, Terris MK, Bollag RJ, Lerner SP, Apolo AB, Villanueva H, Lee M, Sikora AG, Lotan Y, Sreekumar A, Coarfa C, Putluri N. Multi-omics Integration Analysis Robustly Predicts High-Grade Patient Survival and Identifies CPT1B Effect on Fatty Acid Metabolism in Bladder Cancer. Clin Cancer Res 25(12):3689-3701, 2019. e-Pub 2019. PMID: 30846479.
23. Carrero I, Liu HC, Sikora AG, Milosavljevic A. Histoepigenetic analysis of HPV- and tobacco-associated head and neck cancer identifies both subtype-specific and common therapeutic targets despite divergent microenvironments. Oncogene 38(19):3551-3568, 2019. e-Pub 2019. PMID: 30655605.
24. Jung J, Cho KJ, Naji AK, Clemons KN, Wong CO, Villanueva M, Gregory S, Karagas NE, Tan L, Liang H, Rousseau MA, Tomasevich KM, Sikora AG, Levental I, van der Hoeven D, Zhou Y, Hancock JF, Venkatachalam K. HRAS-driven cancer cells are vulnerable to TRPML1 inhibition. EMBO Rep 20(4), 2019. e-Pub 2019. PMID: 30787043.
25. Badr H, Sobrero M, Chen J, Kotz T, Genden E, Sikora AG, Miles B. Associations between pre-, post-, and peri-operative variables and health resource use following surgery for head and neck cancer. Oral Oncol 90:102-108, 2019. e-Pub 2019. PMID: 30846167.
26. Piyarathna DWB, Balasubramanian A, Arnold JM, Lloyd SM, Karanam B, Castro P, Ittmann MM, Putluri N, Navone N, Jones JA, Yu W, Sandulache VC, Sikora AG, Michailidis G, Sreekumar A. ERR1 and PGC1α associated mitochondrial alterations correlate with pan-cancer disparity in African Americans. J Clin Invest 129(6):2351-2356, 2019. e-Pub 2019. PMID: 30920960.
27. Dharmaraj N, Piotrowski SL, Huang C, Newton JM, Golfman LS, Hanoteau A, Koshy ST, Li AW, Pulikkathara MX, Zhang B, Burks JK, Mooney DJ, Lei YL, Sikora AG, Young S. Anti-tumor immunity induced by ectopic expression of viral antigens is transient and limited by immune escape. Oncoimmunology 8(4):e1568809, 2019. e-Pub 2019. PMID: 30906661.
28. Hanoteau A, Newton JM, Krupar R, Huang C, Liu HC, Gaspero A, Gartrell RD, Saenger YM, Hart TD, Santegoets SJ, Laoui D, Spanos C, Parikh F, Jayaraman P, Zhang B, Van der Burg SH, Van Ginderachter JA, Melief CJM, Sikora AG. Tumor microenvironment modulation enhances immunologic benefit of chemoradiotherapy. J Immunother Cancer 7(1):10, 2019. e-Pub 2019. PMID: 30646957.
29. Krishna S, Ulrich P, Wilson E, Parikh F, Narang P, Yang S, Read AK, Kim-Schulze S, Park JG, Posner M, Wilson Sayres MA, Sikora A, Anderson KS. Human Papilloma Virus Specific Immunogenicity and Dysfunction of CD8+ T Cells in Head and Neck Cancer. Cancer Res 78(21):6159-6170, 2018. e-Pub 2018. PMID: 30154146.
30. Krupar R, Schreiber C, Offermann A, Lengerke C, Sikora AG, Thorns C, Perner S. In silico analysis of anti-leukemia immune response and immune evasion in acute myeloid leukemia. Leuk Lymphoma 59(10):2493-2496, 2018. e-Pub 2018. PMID: 29431550.
31. Farina M, Chua CYX, Ballerini A, Thekkedath U, Alexander JF, Rhudy JR, Torchio G, Fraga D, Pathak RR, Villanueva M, Shin CS, Niles JA, Sesana R, Demarchi D, Sikora AG, Acharya GS, Gaber AO, Nichols JE, Grattoni A. Transcutaneously refillable, 3D-printed biopolymeric encapsulation system for the transplantation of endocrine cells. Biomaterials 177:125-138, 2018. e-Pub 2018. PMID: 29886385.
32. Suk R, Mahale P, Sonawane K, Sikora AG, Chhatwal J, Schmeler KM, Sigel K, Cantor SB, Chiao EY, Deshmukh AA. Trends in Risks for Second Primary Cancers Associated With Index Human Papillomavirus-Associated Cancers. JAMA Netw Open 1(5):e181999, 2018. e-Pub 2018. PMID: 30646145.
33. Richardson PA, Kansara S, Chen GG, Sabichi A, Sikora AG, Parke RB, Donovan DT, Chiao E, Sandulache VC. Treatment Patterns in Veterans with Laryngeal and Oropharyngeal Cancer and Impact on Survival. Laryngoscope Investig Otolaryngol 3(4):275-282, 2018. e-Pub 2018. PMID: 30186958.
34. Patel RS, Mohr T, Hartman C, Stach C, Sikora AG, Zevallos JP, Sandulache VC. Tracheoesophageal Prosthesis Use Is Associated With Improved Overall Quality of Life in Veterans With Laryngeal Cancer. Ann Otol Rhinol Laryngol 127(7):421-428, 2018. e-Pub 2018. PMID: 29756480.
35. Newton JM, Hanoteau A, Sikora AG. Enrichment and Characterization of the Tumor Immune and Non-immune Microenvironments in Established Subcutaneous Murine Tumors. J Vis Exp(136), 2018. e-Pub 2018. PMID: 29939180.
36. Leach DG, Dharmaraj N, Piotrowski SL, Lopez-Silva TL, Lei YL, Sikora AG, Young S, Hartgerink JD. STINGel: Controlled release of a cyclic dinucleotide for enhanced cancer immunotherapy. Biomaterials 163:67-75, 2018. e-Pub 2018. PMID: 29454236.
37. Patro A, Guerrini CJ, Huang AT, Sikora AG. The Patient Who Continues to Smoke On-Treatment: An Ethical Dilemma. Otolaryngol Head Neck Surg 158(3):469-472, 2018. e-Pub 2018. PMID: 29337655.
38. Newton JM, Flores-Arredondo JH, Suki S, Ware MJ, Krzykawska-Serda M, Agha M, Law JJ, Sikora AG, Curley SA, Corr SJ. Non-Invasive Radiofrequency Field Treatment of 4T1 Breast Tumors Induces T-cell Dependent Inflammatory Response. Sci Rep 8(1):3474, 2018. e-Pub 2018. PMID: 29472563.
39. Krupar R, Hautmann MG, Pathak RR, Varier I, McLaren C, Gaag D, Hellerbrand C, Evert M, Laban S, Idel C, Sandulache V, Perner S, Bosserhoff AK, Sikora AG. Immunometabolic Determinants of Chemoradiotherapy Response and Survival in Head and Neck Squamous Cell Carcinoma. Am J Pathol 188(1):72-83, 2018. e-Pub 2017. PMID: 29107073.
40. Jayaraman P, Parikh F, Newton JM, Hanoteau A, Rivas C, Krupar R, Rajapakshe K, Pathak R, Kanthaswamy K, MacLaren C, Huang S, Coarfa C, Spanos C, Edwards DP, Parihar R, Sikora AG. TGF-β1 programmed myeloid-derived suppressor cells (MDSC) acquire immune-stimulating and tumor killing activity capable of rejecting established tumors in combination with radiotherapy. Oncoimmunology 7(10):e1490853, 2018. e-Pub 2018. PMID: 30288358.
41. San Martin R, Pathak R, Jain A, Jung SY, Hilsenbeck SG, Piña-Barba MC, Sikora AG, Pienta KJ, Rowley DR. Tenascin-C and Integrin α9 Mediate Interactions of Prostate Cancer with the Bone Microenvironment. Cancer Res 77(21):5977-5988, 2017. e-Pub 2017. PMID: 28916657.
42. Sonawane K, Suk R, Chiao EY, Chhatwal J, Qiu P, Wilkin T, Nyitray AG, Sikora AG, Deshmukh AA. Oral Human Papillomavirus Infection: Differences in Prevalence Between Sexes and Concordance With Genital Human Papillomavirus Infection, NHANES 2011 to 2014. Ann Intern Med 167(10):714-724, 2017. e-Pub 2017. PMID: 29049523.
43. Rosewell Shaw A, Porter CE, Watanabe N, Tanoue K, Sikora A, Gottschalk S, Brenner MK, Suzuki M. Adenovirotherapy Delivering Cytokine and Checkpoint Inhibitor Augments CAR T Cells against Metastatic Head and Neck Cancer. Mol Ther 25(11):2440-2451, 2017. e-Pub 2017. PMID: 28974431.
44. Chew EY, Hartman CM, Richardson PA, Zevallos JP, Sikora AG, Kramer JR, Chiao EY. Risk factors for oropharynx cancer in a cohort of HIV-infected veterans. Oral Oncol 68:60-66, 2017. e-Pub 2017. PMID: 28438295.
45. Laban S, Giebel G, Klümper N, Schröck A, Doescher J, Spagnoli G, Thierauf J, Theodoraki MN, Remark R, Gnjatic S, Krupar R, Sikora AG, Litjens G, Grabe N, Kristiansen G, Bootz F, Schuler PJ, Brunner C, Brägelmann J, Hoffmann TK, Perner S. MAGE expression in head and neck squamous cell carcinoma primary tumors, lymph node metastases and respective recurrences-implications for immunotherapy. Oncotarget 8(9):14719-14735, 2017. PMID: 28146422.
46. Nelson C, Lee J, Ko K, Sikora AG, Bonnen MD, Enkhbaatar P, Ghebre YT. Therapeutic Efficacy of Esomeprazole in Cotton Smoke-Induced Lung Injury Model. Front Pharmacol 8:16, 2017. e-Pub 2017. PMID: 28184197.
47. Deshmukh KS, Suk R, Chiao EY, Chhatwal J, Qui P, Wilkin T, Nyitray AG, Sikora AG, Deshmukh AA. Oral Human Papillomavirus Infection: Differences in Prevalence Between Sexes and Concordance with Genital Human Papillomavirus Infection: Differences in Prevalence Between Sexes and Concordance with Genital Human Papillomavirus Infection, NHANES 2011- 2014. Ann Internal Medicine 167(10):714-724, 2017.
48. Kass JI, Giraldez L, Gooding W, Choby G, Kim S, Miles B, Teng M, Sikora AG, Johnson JT, Myers EN, Duvvuri U, Genden EM, Ferris RL. Oncologic outcomes of surgically treated early-stage oropharyngeal squamous cell carcinoma. Head Neck 38(10):1467-71, 2016. e-Pub 2016. PMID: 27080244.
49. Ramer I, Varier I, Zhang D, Demicco EG, Posner MR, Misiukiewicz K, Genden EM, Miles BA, Teng MS, Sikora AG. Racial disparities in incidence of human papillomavirus-associated oropharyngeal cancer in an urban population. Cancer Epidemiol 44:91-95, 2016. e-Pub 2016. PMID: 27518158.
50. Varier I, Keeley BR, Krupar R, Patsias A, Dong J, Gupta N, Parasher AK, Genden EM, Miles BA, Teng M, Bakst RL, Gupta V, Misiukiewicz KJ, Chiao EY, Scheurer ME, Laban S, Zhang D, Ye F, Cui M, Demicco EG, Posner MR, Sikora AG. Clinical characteristics and outcomes of oropharyngeal carcinoma related to high-risk non-human papillomavirus16 viral subtypes. Head Neck 38(9):1330-7, 2016. e-Pub 2016. PMID: 27080140.
51. de Almeida JR, Moskowitz AJ, Miles BA, Goldstein DP, Teng MS, Sikora AG, Gupta V, Posner M, Genden EM. Cost-effectiveness of transoral robotic surgery versus (chemo)radiotherapy for early T classification oropharyngeal carcinoma: A cost-utility analysis. Head Neck 38(4):589-600, 2016. e-Pub 2015. PMID: 25488048.
52. Wang J, Peng L, Zhang R, Zheng Z, Chen C, Cheung KL, Cui M, Bian G, Xu F, Chiang D, Hu Y, Chen Y, Lu G, Yang J, Zhang H, Yang J, Zhu H, Chen SH, Liu K, Zhou MM, Sikora AG, Li L, Jiang B, Xiong H. 5-Fluorouracil targets thymidylate synthase in the selective suppression of TH17 cell differentiation. Oncotarget 7(15):19312-26, 2016. PMID: 27027355.
53. Stucken CL, de Almeida JR, Sikora AG, Tong CC, Genden EM. Impact of human papillomavirus and smoking on survival outcomes after transoral robotic surgery. Head Neck 38(3):380-6, 2016. e-Pub 2015. PMID: 25351893.
54. Parasher AK, Kidwai SM, Schorn VJ, Goljo E, Weinberg AD, Richards-Kortum R, Sikora AG, Iloreta AM, Govindaraj S, Miles BA. High-resolution microendoscope imaging of inverted papilloma and normal sinonasal mucosa: evaluation of interobserver concordance. Int Forum Allergy Rhinol 5(12):1136-40, 2015. e-Pub 2015. PMID: 26228817.
55. Miles BA, Patsias A, Quang T, Polydorides AD, Richards-Kortum R, Sikora AG. Operative margin control with high-resolution optical microendoscopy for head and neck squamous cell carcinoma. Laryngoscope 125(10):2308-16, 2015. e-Pub 2015. PMID: 26059758.
56. Rettig EM, Wentz A, Posner MR, Gross ND, Haddad RI, Gillison ML, Fakhry C, Quon H, Sikora AG, Stott WJ, Lorch JH, Gourin CG, Guo Y, Xiao W, Miles BA, Richmon JD, Andersen PE, Misiukiewicz KJ, Chung CH, Gerber JE, Rajan SD, D'Souza G. Prognostic Implication of Persistent Human Papillomavirus Type 16 DNA Detection in Oral Rinses for Human Papillomavirus-Related Oropharyngeal Carcinoma. JAMA Oncol 1(7):907-15, 2015. PMID: 26226294.
57. Li M, Pathak RR, Lopez-Rivera E, Friedman SL, Aguirre-Ghiso JA, Sikora AG. The In Ovo Chick Chorioallantoic Membrane (CAM) Assay as an Efficient Xenograft Model of Hepatocellular Carcinoma. J Vis Exp(104), 2015. e-Pub 2015. PMID: 26484588.
58. Lee H, Ruane D, Law K, Ho Y, Garg A, Rahman A, Esterházy D, Cheong C, Goljo E, Sikora AG, Mucida D, Chen BK, Govindraj S, Breton G, Mehandru S. Phenotype and function of nasal dendritic cells. Mucosal Immunol 8(5):1083-98, 2015. e-Pub 2015. PMID: 25669151.
59. Patsias A, Giraldez-Rodriguez L, Polydorides AD, Richards-Kortum R, Anandasabapathy S, Quang T, Sikora AG, Miles B. Feasibility of transoral robotic-assisted high-resolution microendoscopic imaging of oropharyngeal squamous cell carcinoma. Head Neck 37(8):E99-102, 2015. e-Pub 2015. PMID: 25327825.
60. Chen W, Ye F, Cui M, Sikora AG, Wang X, Wang P, Cui X, Guo X, Zhu W, Zhang DY. Protein marker profiling in different T classification in laryngeal squamous cell carcinoma. Head Neck 37(3):357-65, 2015. e-Pub 2014. PMID: 24753215.
61. Lu G, Zhang R, Geng S, Peng L, Jayaraman P, Chen C, Xu F, Yang J, Li Q, Zheng H, Shen K, Wang J, Liu X, Wang W, Zheng Z, Qi CF, Si C, He JC, Liu K, Lira SA, Sikora AG, Li L, Xiong H. Myeloid cell-derived inducible nitric oxide synthase suppresses M1 macrophage polarization. Nat Commun 6:6676, 2015. e-Pub 2015. PMID: 25813085.
62. Levovitz C, Chen D, Ivansson E, Gyllensten U, Finnigan JP, Alshawish S, Zhang W, Schadt EE, Posner MR, Genden EM, Boffetta P, Sikora AG. TGFβ receptor 1: an immune susceptibility gene in HPV-associated cancer. Cancer Res 74(23):6833-44, 2014. e-Pub 2014. PMID: 25273091.
63. Jayaraman P, Alfarano MG, Svider PF, Parikh F, Lu G, Kidwai S, Xiong H, Sikora AG. iNOS expression in CD4+ T cells limits Treg induction by repressing TGFβ1: combined iNOS inhibition and Treg depletion unmask endogenous antitumor immunity. Clin Cancer Res 20(24):6439-51, 2014. e-Pub 2014. PMID: 25278453.
64. Parikh F, Duluc D, Imai N, Clark A, Misiukiewicz K, Bonomi M, Gupta V, Patsias A, Parides M, Demicco EG, Zhang DY, Kim-Schulze S, Kao J, Gnjatic S, Oh S, Posner MR, Sikora AG. Chemoradiotherapy-induced upregulation of PD-1 antagonizes immunity to HPV-related oropharyngeal cancer. Cancer Res 74(24):7205-16, 2014. e-Pub 2014. PMID: 25320012.
65. Cheng J, Kleinberger AJ, Sikora A. Fusobacterium necrophorum in a pediatric retropharyngeal abscess: A case report and review of the literature. Ear Nose Throat J 93(12):E22-4, 2014. PMID: 25531849.
66. Badr H, Gupta V, Sikora A, Posner M. Psychological distress in patients and caregivers over the course of radiotherapy for head and neck cancer. Oral Oncol 50(10):1005-11, 2014. e-Pub 2014. PMID: 25091150.
67. Vila PM, Stucken CL, Morris LG, Posner MR, Genden EM, Boffetta P, Sikora AG. Reduced impact of nodal metastases as a prognostic factor for tonsil cancer in the HPV era. Eur Arch Otorhinolaryngol 271(9):2523-9, 2014. e-Pub 2013. PMID: 24190760.
68. Keeley BR, Islami F, Pourshams A, Poustchi H, Pak JS, Brennan P, Khademi H, Genden EM, Abnet CC, Dawsey SM, Boffetta P, Malekzadeh R, Sikora AG. Prediagnostic serum levels of inflammatory biomarkers are correlated with future development of lung and esophageal cancer. Cancer Sci 105(9):1205-11, 2014. e-Pub 2014. PMID: 25040886.
69. Megwalu UC, Sikora AG. Survival outcomes in advanced laryngeal cancer. JAMA Otolaryngol Head Neck Surg 140(9):855-60, 2014. PMID: 25144163.
70. Jiang N, Muhammad C, Ho Y, Del Signore AG, Sikora AG, Malkin BD. Prevalence of severe obstructive sleep apnea in pediatric adenotonsillectomy patients. Laryngoscope 124(8):1975-8, 2014. e-Pub 2014. PMID: 24668559.
71. de Almeida JR, Villanueva NL, Moskowitz AJ, Miles BA, Teng MS, Sikora A, Gupta V, Posner M, Genden EM. Preferences and utilities for health states after treatment for oropharyngeal cancer: transoral robotic surgery versus definitive (chemo)radiotherapy. Head Neck 36(7):923-33, 2014. e-Pub 2014. PMID: 23595774.
72. Bradley J, Jiang N, Levy L, Richards-Kortum R, Sikora A, Smouha E. High-resolution microendoscope images of middle ear cholesteatoma and surrounding tissue: evaluation of interobserver concordance. Otolaryngol Head Neck Surg 150(4):654-8, 2014. e-Pub 2014. PMID: 24415492.
73. Lopez-Rivera E, Jayaraman P, Parikh F, Davies MA, Ekmekcioglu S, Izadmehr S, Milton DR, Chipuk JE, Grimm EA, Estrada Y, Aguirre-Ghiso J, Sikora AG. Inducible nitric oxide synthase drives mTOR pathway activation and proliferation of human melanoma by reversible nitrosylation of TSC2. Cancer Res 74(4):1067-78, 2014. e-Pub 2014. PMID: 24398473.
74. Villanueva NL, de Almeida JR, Sikora AG, Miles BA, Genden EM. Transoral robotic surgery for the management of oropharyngeal minor salivary gland tumors. Head Neck 36(1):28-33, 2014. e-Pub 2013. PMID: 23554023.
75. Svider PF, Mady LJ, Husain Q, Sikora AG, Setzen M, Baredes S, Eloy JA. Geographic differences in academic promotion practices, fellowship training, and scholarly impact. Am J Otolaryngol 34(5):464-70, 2013. e-Pub 2013. PMID: 23702316.
76. Jang DW, Sikora AG, Leytin A. Thyroglossal duct cyst carcinoma: case report and review of the literature. Ear Nose Throat J 92(9):E12-4, 2013. PMID: 24057908.
77. Morris LG, Sikora AG, Tosteson TD, Davies L. The increasing incidence of thyroid cancer: the influence of access to care. Thyroid 23(7):885-91, 2013. e-Pub 2013. PMID: 23517343.
78. Jianjun Yang , Zhang R, Lu G, Shen Y, Peng L, Zhu C, Cui M, Wang W, Arnaboldi P, Tang M, Gupta M, Qi CF, Jayaraman P, Zhu H, Jiang B, Chen SH, He JC, Ting AT, Zhou MM, Kuchroo VK, Morse HC, Ozato K, Sikora AG, Xiong H. T cell–derived inducible nitric oxide synthase switches off Th17 cell differentiation. J Exp Med 210(7):1447-62, 2013. PMID: 23797094.
79. Jain KS, Sikora AG, Baxi SS, Morris LG. Synchronous cancers in patients with head and neck cancer: risks in the era of human papillomavirus-associated oropharyngeal cancer. Cancer 119(10):1832-7, 2013. e-Pub 2013. PMID: 23423883.
80. Levy LL, Jiang N, Smouha E, Richards-Kortum R, Sikora AG. Optical imaging with a high-resolution microendoscope to identify cholesteatoma of the middle ear. Laryngoscope 123(4):1016-20, 2013. e-Pub 2013. PMID: 23299781.
81. Anvekar RA, Asciolla JJ, Lopez-Rivera E, Floros KV, Izadmehr S, Elkholi R, Belbin G, Sikora AG, Chipuk JE. Sensitization to the mitochondrial pathway of apoptosis augments melanoma tumor cell responses to conventional chemotherapeutic regimens. Cell Death Dis 3:e420, 2012. e-Pub 2012. PMID: 23152056.
82. Vila PM, Park CW, Pierce MC, Goldstein GH, Levy L, Gurudutt VV, Polydorides AD, Godbold JH, Teng MS, Genden EM, Miles BA, Anandasabapathy S, Gillenwater AM, Richards-Kortum R, Sikora AG. Discrimination of benign and neoplastic mucosa with a high-resolution microendoscope (HRME) in head and neck cancer. Ann Surg Oncol 19(11):3534-9, 2012. e-Pub 2012. PMID: 22492225.
83. Jayaraman P, Parikh F, Lopez-Rivera E, Hailemichael Y, Clark A, Ma G, Cannan D, Ramacher M, Kato M, Overwijk WW, Chen SH, Umansky VY, Sikora AG. Tumor-expressed inducible nitric oxide synthase controls induction of functional myeloid-derived suppressor cells through modulation of vascular endothelial growth factor release. J Immunol 188(11):5365-76, 2012. e-Pub 2012. PMID: 22529296.
84. Tong CC, Lau KH, Rivera M, Cannan D, Aguirre-Ghiso J, Sikora AG, Gupta V, Forsythe K, Ko EC, Misiukiewicz K, Gurudutt V, Teng MS, Packer SH, Genden EM, Kao J. Prognostic significance of p16 in locoregionally advanced head and neck cancer treated with concurrent 5-fluorouracil, hydroxyurea, cetuximab and intensity-modulated radiation therapy. Oncol Rep 27(5):1580-6, 2012. e-Pub 2012. PMID: 22322320.
85. Levy LL, Vila PM, Park RW, Schwarz R, Polydorides AD, Teng MS, Gurudutt VV, Genden EM, Miles B, Anandasabapathy S, Gillenwater AM, Richards-Kortum R, Sikora AG. High-Resolution Optical Imaging of Benign and Malignant Mucosa in the Upper Aerodigestive Tract: An Atlas for Image-Guided Surgery. ISRN Minim Invasive Surg 2012, 2012. PMID: 23641314.
86. Jethanamest D, Vila PM, Sikora AG, Morris LG. Predictors of survival in mucosal melanoma of the head and neck. Ann Surg Oncol 18(10):2748-56, 2011. e-Pub 2011. PMID: 21476106.
87. Fu S, Rivera M, Ko EC, Sikora AG, Chen CT, Vu HL, Cannan D, Eisenstein S, Rosenstein BS, Aguirre-Ghiso J, Chen SH, Kao J. Combined Inhibition of Epidermal Growth Factor Receptor and Cyclooxygenase-2 as a Novel Approach to Enhance Radiotherapy. J Cell Sci Ther 1(2), 2011. PMID: 23483082.
88. Genden EM, Kotz T, Tong CC, Smith C, Sikora AG, Teng MS, Packer SH, Lawson WL, Kao J. Transoral robotic resection and reconstruction for head and neck cancer. Laryngoscope 121(8):1668-74, 2011. PMID: 21792953.
89. Morris LG, Sikora AG, Hayes RB, Patel SG, Ganly I. Anatomic sites at elevated risk of second primary cancer after an index head and neck cancer. Cancer Causes Control 22(5):671-9, 2011. e-Pub 2011. PMID: 21327458.
90. Morris LG, Sikora AG, Patel SG, Hayes RB, Ganly I. Second primary cancers after an index head and neck cancer: subsite-specific trends in the era of human papillomavirus-associated oropharyngeal cancer. J Clin Oncol 29(6):739-46, 2011. e-Pub 2010. PMID: 21189382.
91. Sikora AG, Morris LG, Sturgis EM. Bidirectional association of anogenital and oral cavity/pharyngeal carcinomas in men. Arch Otolaryngol Head Neck Surg 135(4):402-5, 2009. PMID: 19380365.
92. Morris LG, Sikora AG, Myssiorek D, DeLacure MD. The basis of racial differences in the incidence of thyroid cancer. Ann Surg Oncol 15(4):1169-76, 2008. e-Pub 2008. PMID: 18246401.
93. Liu C, Lou Y, Lizée G, Qin H, Liu S, Rabinovich B, Kim GJ, Wang YH, Ye Y, Sikora AG, Overwijk WW, Liu YJ, Wang G, Hwu P. Plasmacytoid dendritic cells induce NK cell-dependent, tumor antigen-specific T cell cross-priming and tumor regression in mice. J Clin Invest 118(3):1165-75, 2008. PMID: 18259609.
94. Sikora AG, Shnayder Y, Yee H, DeLacure MD. Oropharyngeal kaposi sarcoma in related persons negative for human immunodeficiency virus. Ann Otol Rhinol Laryngol 117(3):172-6, 2008. PMID: 18444476.
95. Morris LG, Miglietta MA, Sikora AG, Okun MN, Roland JT. Emergency parotidectomy for penetrating zone III neck trauma. Arch Surg 142(12):1206-8, 2007. PMID: 18086989.
96. Morris LG, Sikora AG, Kuriakose MA, DeLacure MD. Tamoxifen therapy for aggressive fibromatosis of the posterior triangle of the neck. Otolaryngol Head Neck Surg 136(4):674-6, 2007. PMID: 17418276.
97. Jethanamest D, Morris LG, Sikora AG, Kutler DI. Esthesioneuroblastoma: a population-based analysis of survival and prognostic factors. Arch Otolaryngol Head Neck Surg 133(3):276-80, 2007. PMID: 17372086.
98. Le BT, Setlur J, Sikora AG, Lee KC. Mycosis fungoides: a case of tonsil involvement. Arch Otolaryngol Head Neck Surg 132(7):794-6, 2006. PMID: 16847192.
99. Liebeskind A, Sikora AG, Komisar A, Slavit D, Fried K. Rates of malignancy in incidentally discovered thyroid nodules evaluated with sonography and fine-needle aspiration. J Ultrasound Med 24(5):629-34, 2005. PMID: 15840794.
100. Sikora AG, Toniolo P, DeLacure MD. The changing demographics of head and neck squamous cell carcinoma in the United States. Laryngoscope 114(11):1915-23, 2004. PMID: 15510014.
101. Kuriakose MA, Chen WT, He ZM, Sikora AG, Zhang P, Zhang ZY, Qiu WL, Hsu DF, McMunn-Coffran C, Brown SM, Elango EM, Delacure MD, Chen FA. Selection and validation of differentially expressed genes in head and neck cancer. Cell Mol Life Sci 61(11):1372-83, 2004. PMID: 15170515.
102. Sikora AG, Lee KC. Otolaryngologic manifestations of immunodeficiency. Otolaryngol Clin North Am 36(4):647-72, 2003. PMID: 14567058.
103. Sikora AG, Mulvihill M. Trends in mortality due to legal intervention in the United States, 1979 through 1997. Am J Public Health 92(5):841-3, 2002. PMID: 11988457.
104. Liu JS, John GR, Sikora A, Lee SC, Brosnan CF. Modulation of interleukin-1beta and tumor necrosis factor alpha signaling by P2 purinergic receptors in human fetal astrocytes. J Neurosci 20(14):5292-9, 2000. PMID: 10884313.
105. Sikora A, Fleischman AR. Physician participation in capital punishment: a question of professional integrity. J Urban Health 76(4):400-8, 1999. PMID: 10609590.
106. Sikora A, Liu J, Brosnan C, Buell G, Chessel I, Bloom BR. Cutting edge: purinergic signaling regulates radical-mediated bacterial killing mechanisms in macrophages through a P2X7-independent mechanism. J Immunol 163(2):558-61, 1999. PMID: 10395640.
107. Redlich CA, Rockwell S, Chung JS, Sikora AG, Kelley M, Mayne ST. Vitamin A inhibits radiation-induced pneumonitis in rats. J Nutr 128(10):1661-4, 1998. PMID: 9772133.

Books (edited and written)

1. Svider P, Chen S, Sikora A. Programming of Myeloid Dervied Suppressor Cells (MDSC): New Opportunities for Target Therapy in the Tumor Immunoenvironment. Ed(s) M Shurin, V Umansky, A Malyguine. Springer - Verlag.