Anudishi Tyagi, Ph.D, MSc., BSc.
Department of Leukemia, Division of Cancer Medicine
Present Title & Affiliation
Primary Appointment
Post Doctoral Fellow, Department of Leukemia - Research, Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas
Education & Training
Degree-Granting Education
| 2019 | All India Institute of Medical Sciences (AIIMS), Delhi, New Delhi, IN, Medical Oncology, Ph.D |
| 2011 | Choudhary Charan Singh University, Meerut, Uttar Pradesh, IN, Biotechnology, M.S |
| 2009 | Jammu University, Jammu, Jammu and Kashmir, IN, B.S |
Postgraduate Training
| 2017-2019 | Senior Research Fellow, All India Institute of Medical Sciences, Houston, New Delhi |
| 2017-2017 | Junior Research Fellow, All India Institute of Medical Sciences, Houston, New Delhi |
| 2016-2017 | Junior Research Fellow, All India Institute of Medical Sciences, Houston, New Delhi |
| 2013-2016 | Junior Research Fellow, All India Institute of Medical Sciences, Houston, New Delhi |
| 2013-2013 | Junior Research Fellow, All India Institute of Medical Sciences, New Delhi |
Honors & Awards
| 2023 | Kimberly Patterson Fellow Leukemia Award, MD Anderson Cancer Center |
| 2022 | ASH abstract Achievement Award, American Society of Hematology |
| 2020 - 2021 | ASH Abstract Achievement Award, American Society of Hematology |
| 2016 | Travel Grant, Indian Council of Medical Research |
Professional Memberships
Selected Publications
Peer-Reviewed Articles
- Eckstrom, A, Tyagi, A, Mahmood, S, Wong, L, Valamehr, B, Rao, A, Agrawal, A, Siddiqui, M, Battula, VL. FT538, iPSC-derived NK cells, enhance AML cell killing when combined with chemotherapy. Journal of Cellular and Molecular Medicine 29(1), 2025. e-Pub 2025. PMID: 39797701.
Other Articles
- Tyagi A, Jaggupilli A, Ly S, Yuan B, El-Dana F, Hegde VL, Anand V, Kumar B, Puppala M, Yin Z, C Wong ST, Mollard A, Vankayalapati H, Foulks JM, Warner SL, Daver N, Borthakur G, Battula V TP-0184 inhibits FLT3/ACVR1 to overcome FLT3 inhibitor resistance and hinder AML growth synergistically with venetoclax. Leukemia, 2024. PMID: 38007585.
- Tyagi A, Ly S, El-Dana F, Yuan B, Jaggupilli A, Grimm S, Konopleva M, Bühring H, Battula V Evidence supporting a role for the immune checkpoint protein B7-H3 in NK cell-mediated cytotoxicity against AML. Blood, 2022. PMID: 35231101.
- Pramanik R, Tyagi A, Agarwala S, Vishnubhatla S, Dhawan D, Bakhshi S Evaluation of vascular endothelial growth factor (VEGF) and thrombospondin-1 as biomarkers of metronomic chemotherapy in progressive pediatric solid malignancies. Indian Pediatrics, 2020. PMID: 32221052.
- Gaur V, Chaudhary S, Tyagi A, Agarwal S, Sharawat SK, Sarkar S, Singh H, Bakhshi S, Sharma P, Kumar S Dysregulation of miRNA expression and their prognostic significance in paediatric cytogenetically normal acute myeloid leukaemia. British Journal of Haematology, 2020. PMID: 32077100.
- Tyagi A, Pramanik R, Bakhshi R, Vishnubhatla S, Bakhshi S Genetic Landscape of Mitochondrial Regulatory Region in Pediatric Acute Myeloid Leukemia: Changes from Diagnosis to Relapse. Journal of Pediatric Genetics, 2019. PMID: 31687256.
- Tyagi A, Pramanik R, Bakhshi R, Singh A, Vishnubhatla S, Bakhshi S Expression of mitochondrial genes predicts survival in pediatric acute myeloid leukemia. International Journal of Hematology, 2019. PMID: 31119613.
- Tyagi A, Pramanik R, Vishnubhatla S, Bakhshi R, Bakhshi S Prognostic impact of mitochondrial DNA D-loop variations in pediatric acute myeloid leukemia. Oncotarget, 2019. PMID: 30863493.
- Tyagi A, Pramanik R, Bakhshi R, Vishnubhatla S, Bakhshi S Apoptosis: A biomarker of high‐risk phenotype in pediatric acute myeloid leukemia?. International Journal of Laboratory Hematology, 2019. PMID: 30383325.
- Tyagi A, Pramanik R, Chaudhary S, Chopra A, Bakhshi S Cytogenetic profiles of 472 Indian children with acute myeloid leukemia. Indian Pediatrics, 2018. PMID: 29978812.
- Tyagi A, Pramanik R, Tyagi A, Chopra A, Kumar A, Vishnubhatla S, Bakhshi S Myeloid sarcoma predicts superior outcome in pediatric AML; can cytogenetics solve the puzzle?. Clinical Lymphoma Myeloma and Leukemia, 2018. PMID: 29680411.
- Tyagi A, Pramanik R, Vishnubhatla S, Ali S, Bakhshi R, Chopra A, Singh A, Bakhshi S Pattern of mitochondrial D-loop variations and their relation with mitochondrial encoded genes in pediatric acute myeloid leukemia. Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis, 2018. PMID: 29883862.
Abstracts
- Tyagi A, Bakhshi S, Singh A, Chaudhary S, Dhawan D, Bakhshi R. High Mitochondrial Respiratory Chain Complex V is Associated with Inferior Survival in Acute Myeloid Leukemia: A Study of 57 Pediatric Patients. International Society of Pediatric and Oncology.
- Kumar A, Tyagi A, Pramanik R, Batra A, Chopra A, Bakhshi S. Characteristics and Outcome of Myeloid Sarcoma in Children at A Tertiary Care Centre from India: A Study of 126 Patients. International Society of Pediatric Oncology.
- Kumar A, Tyagi A, Pramanik R, Batra A, Chopra A, Bakhshi S. Differential expression of various miRNAs in pediatric cytogenetically normal acute myeloid leukemia (CN-AML). Annals of Oncology.
- Tyagi A, Yuan B, Ly S, El-Dana F, Kuruvilla V, Zhang Q, Zhou X, deCrombrugghe B, Konopleva M, Andreeff M, Battula VL. Osteoprogenitor Cells, but Not Mature Osteoblasts/Osteocytes that Support AML Growth in the Bone Marrow Microenvironment. Society of Hemtology and Oncology.
- Tyagi A, Yuan B, Ly S, El-Dana F, Kuruvilla VM, Zhang Q, Peterson CB, Zhou X, Decrombrugghe B, Andreeff M, Konopleva M, Amini B, Battula VL. AML Cells Alter Bone Homeostasis By Promoting the Formation of Immature Bone and Resorption of Mature Bone That Supports Leukemia Progression. American Society of Hematology.
- Tyagi A, Ly S, El-Dana F, Yuan B, Grimm S, Bühring H, Battula VL. Anti-B7-H3 Antibody (T-1A5) Blocks Immunomodulatory Function of B7-H3 and Enhances NK Cell-Mediated Cytotoxicity Against Acute Myeloid Leukemia Cells. American Society of Hematology.
- Tyagi A, Ly S, Yuan B, El-Dana F, Anand V, Jaggupilli A, Borthakur G, Foulks JM, Warner SL, Battula VL. Activin-like Kinase 2 (ALK2/ACVR1) Is a Resistance Factor and Therapeutic Vulnerability to FLT3 Inhibition in Acute Myeloid Leukemia. American Society of Hematology.
- Tyagi A, Ly S, Yuan B, El-Dana F, Jaggupilli A, Foulks J, Warner S, Battula V. Novel FLT3-ALK2 Dual Inhibitor TP-0184 Inhibits Leukemia Growth by Targeting Serine Biosynthesis in FLT3-ITD-Positive AML Cells. Society of hematology and Oncology.
- Tyagi A, Ly S, El-Dana F, Yuan B, Jaggupilli A, Grimm S, Bover L, Buhring H, Battula V. Novel Anti–B7-H3 Blocking Antibody Enhances NK Cell–Mediated Cytotoxicity and Improves Outcomes in AML-Bearing Mice. Society of Hematology and Oncology.
- Anand V, Tyagi A, Battula VL. Anti-B7-H3 Antibody (T-1A5) Blocks Immunomodulatory Function of B7-H3 and Enhances NK and T Cell–Mediated Cytotoxicity against Breast Cancer Cells. American Association of cancer Research.
- Eckstrom A, Tyagi A, Siddiqui M, Mahmood S, Wong L, Valamehr BB, Daver N, Battula VL. FT538, iPSC-Derived NK Cells Are Potent Inducers of Apoptosis in AML Cells and Their Effect Is Synergistic in Combination with Approved Therapeutic Strategies. American Association of cancer Research.
- Tyagi A, Siddiqui M, Kurth I, Takeda S, Eckstrom A, Borgman J, Maiti A, Battula VL. Targeting Myeloid Epithelial Tyrosine Kinase (MERTK) Receptor in Acute Myeloid Leukemia Using a Novel Antibody Drug Conjugate, Rgx-019-MMAE. American Association of Cancer Research.
Selected Presentations & Talks
International Presentations
- 2023. B7-H3 blockade in combination with natural killer cell activity enhancers including NKTR-255 and venetoclax synergistically induces cytotoxicity in B7-H3+ AML cells. Poster. American Association of Cancer Research, US.
- 2022. Novel Anti–B7-H3 Blocking Antibody Enhances NK Cell–Mediated Cytotoxicity and Improves Outcomes in AML-Bearing Mice. Poster. American Society of Hematology, US.
- 2022. Activin-like Kinase 2 (ALK2/ACVR1) Is a Resistance Factor and Therapeutic Vulnerability to FLT3 Inhibition in Acute Myeloid Leukemia. Invited. American Society of hematology, US.
- 2021. Anti-B7-H3 Antibody (T-1A5) Blocks Immunomodulatory Function of B7-H3 and Enhances NK Cell-Mediated Cytotoxicity Against Acute Myeloid Leukemia Cells. Poster. American Society of Hematology, US.
- 2020. AML Cells Alter Bone Homeostasis By Promoting the Formation of Immature Bone and Resorption of Mature Bone That Supports Leukemia Progression. Poster. American Society of Hematology, US.
- 2016. High Mitochondrial Respiratory Chain Complex V is Associated with Inferior Survival in Acute Myeloid Leukemia: A Study of 57 Pediatric Patients. Poster. International Society of pediatric Oncology, US.
Patient Reviews
CV information above last modified April 22, 2025