Benny Chang, PHD
Department of Emergency Medicine, Division of Internal Medicine
Present Title & Affiliation
Primary Appointment
Assistant Professor, Department of Section of Nephrology, Division of Internal Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas
Dual/Joint/Adjunct Appointment
Assistant Professor, Department of Section of Nephrology, The University of Texas MD Anderson Cancer Center, Houston, Texas
Education & Training
Degree-Granting Education
| 2013 | St. Thomas University, Houston, TX, US, Pastoral Studies, Masters of Art |
| 1995 | National Sun Yat-Sen University, Taiwan, TW, Masters of Science |
| 1995 | University of Texas-HSC-Houston, Houston, TX, US, PhD |
| 1982 | National College of Marine Science and Technology, Taiwan, TW, Marine Science and Technology, Bachlors of Science |
Postgraduate Training
| 1997-2000 | Research Fellowship, Baylor College of Medicine, Houston, Texas |
| 1996-1997 | Research Fellowship, Research Training in Pediatric Gastroenterology, Baylor College of Medicine, Houston, Texas |
| 1995-1996 | Postdoctoral Fellowship, Baylor College of Medicine, Houston, Texas |
Experience & Service
Faculty Academic Appointments
Assistant Professor, Department of Molecular and Cellular Oncology, Baylor College of Medicine, Houston, Texas, 2001 - 2019
Lecturer, Department of Aquaculture, National Kaohsiung Institute of Marine Technology, Taiwan, 1987
Other Professional Positions
Director, DNA Sequencing Core, Baylor College of Medicine, Houston, Texas, 2016
Director, Gene Vector Core, Baylor College of Medicine, Houston, Texas, 2015 - 2016
Associate Director, Gene Vector Core, Baylor College of Medicine, Houston, Texas, 2012 - 2015
Grant & Contract Support
| Date: | 2020 - 2025 |
| Title: | Role of Rho Kinases in Diabetic Nephropathy |
| Funding Source: | NIH/NIDDK |
| Role: | Co-PI |
| ID: | 1RO1DK078900-01A2 |
| Date: | 2016 - 2018 |
| Title: | , Lipid Droplets Control Their Own Existence |
| Funding Source: | American Heart Association |
| Role: | PI |
| ID: | 16GRNT30990040 |
| Date: | 2010 - 2014 |
| Title: | Role of Adipose Differentiation Related Protein (ADFP) in Hepatic Lipid /Droplet Biogenesis, Triacylglycerol Homeostasis and VLDL Secretion |
| Funding Source: | NIH/NIDDK |
| Role: | PI |
| ID: | 1RO1DK84495-01A2 |
| Date: | 2010 - 2015 |
| Title: | The role and mechanism of high glucose-induced PI-BMDCs and PI-BMDC-neuron cell fusion may lead to a fundamental change in our understanding of the pathogenesis of diabetic neuropathy |
| Funding Source: | NIH/NHLBI |
| Role: | Key |
| ID: | RO1 HL51586-17 |
| Date: | 2009 - 2014 |
| Title: | The effects of chronic Rho kinase inhibition on the progression of diabetic nephropathy |
| Funding Source: | NIH/NIDDK |
| Role: | Key |
| ID: | 1RO1DK078900-01A2 |
| Date: | 2005 - 2006 |
| Title: | Mechanism of Fatty Liver in MTP Deficiency: Crucial Role of ADRP |
| Funding Source: | Pfizer Pharmaceutical |
| Role: | PI |
| Date: | 2001 |
| Title: | ADRP and Its Role in Hepatic Steatosis |
| Funding Source: | NIH/NIDDK |
| Role: | PI |
| ID: | P30 DK56338 |
Selected Publications
Peer-Reviewed Articles
- Mise, K, Long, J, Galvan, D, Ye, Z, Fan, G, Sharma, R, Serysheva, I, Moore, TI, Jeter, CR, Anna Zal, M, Araki, M, Wada, J, Schumacker, PT, Chang, B, Danesh, FR. NDUFS4 regulates cristae remodeling in diabetic kidney disease. Nature communications 15(1), 2024. e-Pub 2024. PMID: 38438382.
- Chen, Z, Wang, S, Pottekat, A, Duffey, A, Jang, I, Chang, B, Cho, J, Finck, BN, Davidson, NO, Kaufman, RJ. Conditional hepatocyte ablation of PDIA1 uncovers indispensable roles in both APOB and MTTP folding to support VLDL secretion. Molecular Metabolism 80, 2024. e-Pub 2024. PMID: 38211723.
- Li, L, Long, J, Mise, K, Poungavrin, N, Lorenzi, PL, Mahmud, I, Tan, L, Saha, PK, Kanwar, YS, Chang, B, Danesh, FR. The transcription factor ChREBP links mitochondrial lipidomes to mitochondrial morphology and progression of diabetic kidney disease. Journal of Biological Chemistry 299(9), 2023. e-Pub 2023. PMID: 37611830.
- Li, L, Long, J, Mise, K, Poungavrin, N, Lorenzi, PL, Mahmud, I, Tan, L, Saha, PK, Kanwar, YS, Chang, B, Danesh, FR. The transcription factor ChREBP links mitochondrial lipidomes to mitochondrial morphology and progression of diabetic kidney disease. Journal of Biological Chemistry 299(9), 2023. e-Pub 2023. PMID: 37611830.
Other Articles
- Mise, K, Long, J, Galvan, D, Ye, Z, Fan, G, Sharma, R, Serysheva, I, Moore, T, Jeter, CR, Anna Zal, M, Araki, M, Wada, J, Schumacker, PT, Chang, B, Danesh, FR Correction to. Nature communications 15(1), 2024. PMID: 38589378.
Abstracts
- Mise K, Long J, Galvan DL, Ye Z, Fan G, Sharma R, Serysheva II, Moore TI, Jeter CR, Anna Zal M, Araki M, Wada J, Schumacker PT, Chang BH, Danesh FR. Publisher Correction: NDUFS4 regulates cristae remodeling in diabetic kidney disease. Nat Commun 15(1):3022, 2024. e-Pub 2024. PMID: 38589378.
- Mise K, Long J, Galvan DL, Ye Z, Fan G, Sharma R, Serysheva II, Moore TI, Jeter CR, Anna Zal M, Araki M, Wada J, Schumacker PT, Chang BH, Danesh FR. NDUFS4 regulates cristae remodeling in diabetic kidney disease. Nat Commun 15(1):1965, 2024. e-Pub 2024. PMID: 38438382.
- Chen Z, Wang S, Pottekat A, Duffey A, Jang I, Chang BH, Cho J, Finck BN, Davidson NO, Kaufman RJ. Conditional hepatocyte ablation of PDIA1 uncovers indispensable roles in both APOB and MTTP folding to support VLDL secretion. Mol Metab 80:101874, 2024. e-Pub 2024. PMID: 38211723.
- Li L, Long J, Mise K, Poungavrin N, Lorenzi PL, Mahmud I, Tan L, Saha PK, Kanwar YS, Chang BH, Danesh FR. The transcription factor ChREBP links mitochondrial lipidomes to mitochondrial morphology and progression of diabetic kidney disease. J Biol Chem 299(9):105185, 2023. e-Pub 2023. PMID: 37611830.
- Mise K, Long J, Galvan DL, Ye Z, Fan G, Serysheva II, Moore TI, Wada J, Schumacker PT, Chang BH, Danesh FR. NDUFS4 Regulates Cristae Remodeling in Diabetic Kidney Disease. Res Sq, 2023. e-Pub 2023. PMID: 37461606.
Patient Reviews
CV information above last modified March 26, 2026