Byron Lee, MD, PhD
Department of Urology, Division of Surgery
About Byron Lee
Byron Lee, MD, PhD is an Associate Professor in the Department of Urology at The University of Texas MD Anderson Cancer Center. He attended medical and graduate school at Johns Hopkins School of Medicine, where he developed an interest in urologic cancer research with a focus on cancer epigenetics. After finishing urology residency at Cleveland Clinic, he spent one year at Stanford University as a postdoctoral fellow before completing urologic oncology fellowship training at Memorial Sloan Kettering Cancer Center. He returned to Cleveland Clinic as a staff surgeon-scientist before joining the faculty at MD Anderson.
In addition to performing endoscopic and robotic surgery for bladder cancer patients, Dr. Lee leads a basic and translational research laboratory that focuses on examining the biologic effects of chromatin modifier gene mutations on the urothelium and tumor microenvironment. He has successfully competed for a Kimmel Scholar Award from the Sidney Kimmel Foundation, a Young Investigator Award from the Bladder Cancer Advocacy Network, a K08 career development award from the National Cancer Institute, and a multi-PI U01 from the National Institute of Diabetes and Digestive Kidney Diseases that seeks to generate a single cell transcriptome and regulatory map of the human ureter and bladder. His long-term career goal is to improve the lives of bladder cancer patients through excellent surgical care and impactful research.
Present Title & Affiliation
Primary Appointment
Associate Professor, Department of Urology, Division of Surgery, The University of Texas MD Anderson Cancer Center, Houston, Texas
Dual/Joint/Adjunct Appointment
Associate Professor, Department of Urology, The University of Texas MD Anderson Cancer Center, Houston, Texas
Education & Training
Degree-Granting Education
| 2007 | Johns Hopkins University School of Medicine, Baltimore, Maryland, US, Ph.D. in Cellular and Molecular Medicine |
| 2007 | Johns Hopkins University School of Medicine, Baltimore, Maryland, US, M.D |
| 1998 | Johns Hopkins University, Baltimore, Maryland, US, B.A. in Biology with General Honors |
Postgraduate Training
| 2014-2016 | Clinical Fellowship, Urologic Oncology, Memorial Sloan Kettering Cancer Center, New York, New York |
| 2013-2014 | Postdoctoral Fellowship, Stanford University School of Medicine, Stanford, California |
| 2008-2013 | Residency, Urology, Cleveland Clinic Glickman Urological & Kidney Institute, Cleveland, Ohio |
| 2007-2008 | Internship, General Surgery, Cleveland Clinic, Cleveland, Ohio |
Board Certifications
| 2019 | American Board of Urology |
Experience & Service
Other Appointments/Responsibilities
Regular Member, Genetics and Epigenetics Program, UT Graduate School of Biomedical Sciences at Houston, Houston, TX, 2023 - Present
Institutional Committee Activities
Member, Division of Surgery Basic/Translational Research Committee, 2023 - Present
Honors & Awards
| 2020 | Early-Career Investigators Showcase, American Urological Association |
| 2017 | Bladder Cancer Advocacy Network Young Investigator Award, Bladder Cancer Advocacy Network |
| 2017 | Kimmel Scholars Award, Sidney Kimmel Foundation |
| 2016 | Chairman’s Award for Excellence in Basic Science, Memorial Sloan Kettering Cancer Center |
| 2013 | William E. Lower Memorial Award, Cleveland Clinic |
| 2012 | Outstanding Laparoendoscopic Resident Award, Society of Laparoendoscopic Surgeons |
| 1998 | Golden Key International Honor Society |
| 1998 | Phi Beta Kappa |
Professional Memberships
Selected Publications
Peer-Reviewed Articles
- Mokkapati S, Manyam G, Steinmetz AR, Tholomier C, Martini A, Choi W, Czerniak B, Lee BH, Dinney CP, McConkey DJ. Molecular profiling of bladder cancer xenografts defines relevant molecular subtypes and provides a resource for biomarker discovery. Transl Oncol 52:102269, 2025. e-Pub 2025. PMID: 39808845.
- Santo B, Fink EE, Krylova AE, Lin YC, Eltemamy M, Wee A, Wessely O, Lee BH, Ting AH. Exploring the utility of snRNA-seq in profiling human bladder tissue: A comprehensive comparison with scRNA-seq. iScience 28(1):111628, 2025. e-Pub 2025. PMID: 39850354.
- Ramanujan S, Orji P, Chiu A, Kumar SS, Jevnikar W, Cox B, Montague D, Almassi N, Lee B, Bena J, Morrison S, Chehroudi AC, Bajic P, De S. Benign Prostatic Hyperplasia Knowledge Deficits Among Male Urology Patients. Urology, 2025. e-Pub 2025. PMID: 39824366.
- Moussa, MJ, Tabet, GC, Siefker-Radtke, AO, Xiao, L, Wilson, NR, Gao, J, Logothetis, CJ, Grivas, PD, Lee, B, Shah, AY, Msaouel, P, Li, R, Clemente, LC, Zhao, J, Tannir, NM, Kamat, A, Hansel, DE, Guo, CC, Campbell, M, Alhalabi, O. Histopathologic Progression and Metastatic Relapse Outcomes in Small Cell Neuroendocrine Carcinomas of the Urinary Tract. Cancer medicine 14(2), 2025. e-Pub 2025. PMID: 39831734.
- Moussa MJ, Tabet GC, Siefker-Radtke AO, Xiao L, Wilson NR, Gao J, Logothetis CJ, Grivas P, Lee B, Shah AY, Msaouel P, Li R, Clemente LC, Zhao J, Tannir NM, Kamat AM, Hansel DE, Guo CC, Campbell MT, Alhalabi O. Histopathologic Progression and Metastatic Relapse Outcomes in Small Cell Neuroendocrine Carcinomas of the Urinary Tract. Cancer Med 14(2):e70594, 2025. e-Pub 2025. PMID: 39831734.
- Campbell, R, Wood, A, Michael, PD, Shin, D, Pramod, N, Haywood, S, Eltemamy, M, Weight, C, Haber, GP, Lee, B, Myles, J, McKenney, J, Nguyen, JK, Williamson, SR, Przybycin, CG, Alaghehbandan, R, Almassi, N. Impact of pathologic re-review on grade, clinical stage, and risk stratification for patients with nonmuscle invasive bladder cancer. Urologic Oncology: Seminars and Original Investigations 42(11):372.e21-372.e27, 2024. e-Pub 2024. PMID: 38880703.
- Carriere P, Alhalabi O, Gao J, Mohamad O, Campbell MT, Shah A, Goswami S, Bree K, Lee B, Navai N, Mok H, Mayo L, Guo C, Nguyen Q, McGuire S, Park R, Shah S, Hoffman K, Frank S, Tang C, Choi S, Kamat A, Hassanzadeh C. Bladder-preserving radiation therapy for patients with locally advanced and node-positive bladder cancer. Clin Transl Radiat Oncol 49:100866, 2024. e-Pub 2024. PMID: 39403573.
- Myers AA, Fang AM, Moussa MJ, Hwang H, Wilson NR, Campbell MT, Msaouel P, Lee BH, Guo CC, Zhang M, Zhao J, Siefker-Radtke AO, Kamat AM, Alhalabi O. Impact of systemic therapy on clinical T1 small-cell neuroendocrine carcinoma of the bladder. ESMO Open 9(11):103964, 2024. e-Pub 2024. PMID: 39471563.
- Plumber SA, Tate T, Al-Ahmadie H, Chen X, Choi W, Basar M, Lu C, Viny A, Batourina E, Li J, Gretarsson K, Alija B, Molotkov A, Wiessner G, Lee BHL, McKiernan J, McConkey DJ, Dinney C, Czerniak B, Mendelsohn CL. Rosiglitazone and trametinib exhibit potent anti-tumor activity in a mouse model of muscle invasive bladder cancer. Nat Commun 15(1):6538, 2024. e-Pub 2024. PMID: 39095358.
- Myers AA, Tan WS, Grajales V, Hwang H, Bree KK, Navai N, Lee BH, Dinney CPN, Kamat AM. Challenging the Paradigm of "BCG-unresponsive" Bladder Cancer: Does Additional Bacillus Calmette-Guerin Have an Effect?. Eur Urol 86(4):366-368, 2024. e-Pub 2024. PMID: 38879371.
- Knorr J, Lone Z, Werneburg G, Adler A, Agudelo J, Suryavanshi M, Campbell RA, Ericson K, Qiu H, Bajic P, Haber GP, Weight CJ, Ahern PP, Almassi N, Miller AW, Lee BH. An exploratory study investigating the impact of the bladder tumor microbiome on Bacillus Calmette Guerin (BCG) response in non-muscle invasive bladder cancer. Urologic Oncology: Seminars and Original Investigations 42(9):291.e1-291.e11, 2024. e-Pub 2024. PMID: 38664180.
- Campbell, R, Khanna, A, Boorjian, SA, Knorr, JM, Cox, R, Nicholas, M, Cheville, JC, Sharma, V, Murthy, PB, Tarrell, R, Thapa, P, Tollefson, MK, Thompson, RH, Frank, I, Karnes, RJ, Haber, GP, Lee, BH. Impact of Neoadjuvant Chemotherapy on Pathologic Downstaging in Patients With Variant Histology Undergoing Radical Cystectomy. Clinical Genitourinary Cancer 22(2):157-163.e1, 2024. e-Pub 2024. PMID: 38008690.
- Steinmetz AR, Pierce M, Martini A, Tholomier C, Manyam G, Chen Y, Sood A, Duplisea JJ, Johnson BA, Czerniak BA, Lee BH, Jagannath C, Yla-Herttuala S, Parker NR, McConkey DJ, Dinney CP, Mokkapati S. Single-cell RNA sequencing analysis identifies acute changes in the tumor microenvironment induced by interferon alpha gene therapy in a murine bladder cancer model. Front Immunol 15:1387229, 2024. e-Pub 2024. PMID: 39559365.
- Lone, Z, Benidir, T, Wood, A, Campbell, RA, Alaghehbandan, R, Li, J, Haber, GP, Eltemamy, M, Haywood, SC, Weight, CJ, Lee, BH, Almassi, N. Oncologic outcomes of intravesical therapy in the management of nonmuscle invasive bladder cancer with variant histology. Urologic Oncology: Seminars and Original Investigations 42(3):71.e1-71.e7, 2023. PMID: 38135626.
- Contieri, R, Hensley, PJ, Tan, WS, Grajales, V, Bree, KK, Nogueras Gonzalez, G, Lee, B, Navai, N, Dinney, CP, Kamat, A. Oncological Outcomes for Patients with European Association of Urology Very High-risk Non-muscle-Invasive Bladder Cancer Treated with Bacillus Calmette-Guérin or Early Radical Cystectomy. European Urology Oncology 6(6):590-596, 2023. e-Pub 2023. PMID: 37558542.
- Miller, BT, Ellis, RC, Walsh, RM, Joyce, D, Simon, R, Almassi, N, Lee, B, DeBernardo, RL, Steele, SR, Haywood, S, Beffa, L, Tu, C, Rosen, MJ. Physiologic tension of the abdominal wall. Surgical endoscopy 37(12):9347-9350, 2023. e-Pub 2023. PMID: 37640951.
- Qiu, H, Makarov, V, Bolzenius, JK, Halstead, A, Parker, Y, Wang, A, Iyer, GV, Wise, H, Kim, D, Thayaparan, V, Lindner, D, Haber, GP, Ting, AH, Ren, B, Chan, TA, Arora, V, Solit, DB, Lee, BH. KDM6A Loss Triggers an Epigenetic Switch That Disrupts Urothelial Differentiation and Drives Cell Proliferation in Bladder Cancer. Cancer Research 83(6):814-829, 2023. e-Pub 2023. PMID: 36638328.
- Fink, EE, Sona, S, Lee, BH, Ting, AH. Processing and cryopreservation of human ureter tissues for single-cell and spatial transcriptomics assays. STAR Protocols 3(4), 2022. e-Pub 2022. PMID: 36595885.
- Benidir, T, Lone, Z, Zhang, A, Nowacki, AS, Munoz-Lopez, C, Hegde, P, Fung, K, Fajnzylber, J, Abouassaly, R, Berglund, RK, Klein, EA, Eltemamy, M, Kaouk, JH, Weight, C, Almassi, N, Pascal-Haber, G, Lee, BH. Comparing Pathologic and Survival Outcomes Between Primary and Secondary Muscle Invasive Bladder Cancer When Treated by Radical Cystectomy With or Without Neoadjuvant Chemotherapy. Urology 168:137-142, 2022. e-Pub 2022. PMID: 35772481.
- Lone, Z, Zhang, A, Benidir, T, Corrigan, D, Munoz-Lopez, C, Hegde, P, Fung, K, Fajnzylber, J, Campbell, R, Ramkumar, R, Murthy, PB, Eltemamy, M, Kaouk, JH, Pascal-Haber, G, Almassi, N, Weight, C, Lee, BH. The role of enhanced recovery after surgery protocols in the development of acute kidney injury following radical cystectomy. Urologic Oncology: Seminars and Original Investigations 40(10):453.e1-453.e7, 2022. e-Pub 2022. PMID: 35953395.
- Fink, EE, Sona, S, Tran, U, Desprez, PE, Bradley, M, Qiu, H, Eltemamy, M, Wee, A, Wolkov, M, Nicolas, MM, Min, B, Haber, GP, Wessely, O, Lee, BH, Ting, AH. Single-cell and spatial mapping Identify cell types and signaling networks in the human ureter. Developmental cell 57(15):1899-1916.e6, 2022. e-Pub 2022. PMID: 35914526.
- Knorr, JM, Campbell, R, Cockrum, J, Dalton, JE, Murthy, PB, Berglund, RK, Cullen, J, Weight, C, Almassi, N, Abouassaly, R, Kaouk, JH, Haber, GP, Lee, BH. Neighborhood Socioeconomic Disadvantage Associated With Increased 90-Day Mortality Following Radical Cystectomy. Urology 163:177-184, 2022. e-Pub 2022. PMID: 34974027.
- Lone, Z, Campbell, R, Corrigan, D, Ramkumar, R, Hegde, P, Rahmy, A, Murthy, PB, Haber, GP, Almassi, N, Lee, BH. Ability of the surgical Apgar score to predict acute kidney injury following radical cystectomy. Urologic Oncology: Seminars and Original Investigations 40(5):194.e1-194.e6, 2022. e-Pub 2022. PMID: 34654645.
- Khanna, A, Miest, T, Sharma, V, Campbell, R, Hensley, PJ, Thapa, P, Zganjar, A, Tollefson, MK, Thompson, RH, Frank, I, Karnes, RJ, Murthy, PB, Haber, GP, Navai, N, Kamat, A, Dinney, CP, Lee, BH, Boorjian, SA. Role of Lymphadenectomy during Radical Cystectomy for Nonmuscle-Invasive Bladder Cancer. Journal of Urology 207(3):551-558, 2022. e-Pub 2022. PMID: 34694143.
- Miest, T, Khanna, A, Sharma, V, Hensley, PJ, Campbell, R, Thapa, P, Zganjar, A, Tollefson, MK, Thompson, RH, Frank, I, Karnes, RJ, Potretzke, AM, Matin, S, Murthy, PB, Haber, GP, Lee, BH, Boorjian, SA. Development and Validation of a Risk-Adapted Scoring Model for Metachronous Upper Tract Urothelial Carcinoma following Radical Cystectomy. Journal of Urology 207(2):284-292, 2022. e-Pub 2022. PMID: 34547921.
- Murthy, PB, Lone, Z, Corrigan, D, Campbell, R, Munoz-Lopez, C, Caveney, M, Gerber, D, Ericson, K, Thomas, LJ, Zhang, JH, Kaouk, JH, Weight, C, Berglund, RK, Haber, GP, Lee, BH. Survival outcomes following radical cystectomy in patients with prior pelvic radiation for prostate cancer. Urologic Oncology: Seminars and Original Investigations 40(1):10.e13-10.e19, 2022. e-Pub 2022. PMID: 34400070.
- Werneburg, GT, Keslar, KS, Gotwald, P, Doolittle, J, Vij, SC, Lee, BH, Shoskes, DA. Neuroinflammatory gene expression analysis reveals potential novel mediators and treatment targets in interstitial cystitis with Hunner lesions. Translational Andrology and Urology 10(11):4100-4109, 2021. e-Pub 2021. PMID: 34984176.
- Murthy, PB, Lone, Z, Munoz-Lopez, C, Ericson, JK, Thomas, LJ, Caveney, M, Gerber, D, Khanna, A, Abouassaly, R, Haber, GP, Lee, BH. Comparison of Oncologic Outcomes Following Open and Robotic-assisted Radical Cystectomy with both Extracorporeal and Intracorporeal Urinary Diversion. Urology 154:184-190, 2021. e-Pub 2021. PMID: 33891929.
- Lone, Z, Murthy, PB, Zhang, JH, Ericson, K, Thomas, LJ, Khanna, A, Haber, GP, Lee, BH. Comparison of renal function after open radical cystectomy, extracorporeal robot assisted radical cystectomy, and intracorporeal robot assisted radical cystectomy. Urologic Oncology: Seminars and Original Investigations 39(5):301.e1-301.e9, 2021. e-Pub 2021. PMID: 33036904.
- Knorr, JM, Ericson, K, Zhang, JH, Murthy, PB, Nowacki, AS, Munoz-Lopez, C, Thomas, LJ, Haber, GP, Lee, BH. Comparison of Major Complications at 30 and 90 Days Following Radical Cystectomy. Urology 148:192-197, 2021. e-Pub 2021. PMID: 32888983.
- Fallah, J, Díaz-Montero, CM, Rayman, P, Wei, W, Finke, JH, Kim, JS, Pavicic, PG, Lamenza, M, Dann, P, Company, D, Stephenson, AJ, Campbell, S, Haber, GP, Lee, BH, Mian, OY, Gilligan, TD, Garcia, JA, Rini, BI, Ornstein, MC, Grivas, PD. Myeloid-Derived Suppressor Cells in Nonmetastatic Urothelial Carcinoma of Bladder Is Associated With Pathologic Complete Response and Overall Survival. Clinical Genitourinary Cancer 18(6):500-508, 2020. e-Pub 2020. PMID: 32340875.
- Ericson, K, Thomas, LJ, Zhang, JH, Knorr, JM, Khanna, A, Crane, A, Zampini, A, Murthy, PB, Berglund, RK, Haber, GP, Lee, BH. Uretero-Enteric Anastomotic Stricture Following Radical Cystectomy. Urology 144:130-135, 2020. e-Pub 2020. PMID: 32653565.
- Khanna, A, Zampini, A, Crane, A, Ericson, K, Murthy, PB, Fascelli, M, Faris, A, Haber, GP, Lee, BH. Reducing Readmissions Following Radical Cystectomy. Urology 141:114-118, 2020. e-Pub 2020. PMID: 32272122.
- Nanavaty, V, Abrash, EW, Hong, C, Park, S, Fink, EE, Li, Z, Sweet, TJ, Bhasin, JM, Singuri, S, Lee, BH, Hwang, TH, Ting, AH. DNA Methylation Regulates Alternative Polyadenylation via CTCF and the Cohesin Complex. Molecular cell 78(4):752-764.e6, 2020. e-Pub 2020. PMID: 32333838.
- Sheng, IY, Díaz-Montero, CM, Rayman, P, Wei, W, Finke, JH, Kim, JS, Pavicic, PG, Lamenza, M, Company, D, Stephenson, AJ, Campbell, S, Haber, GP, Lee, BH, Mian, OY, Gilligan, TD, Rini, BI, Garcia, JA, Grivas, PD, Ornstein, MC. Blood Myeloid-Derived Suppressor Cells Correlate with Neutrophil-to-Lymphocyte Ratio and Overall Survival in Metastatic Urothelial Carcinoma. Targeted oncology 15(2):211-220, 2020. e-Pub 2020. PMID: 32207064.
- Zhang, JH, Ericson, K, Thomas, LJ, Knorr, JM, Khanna, A, Crane, A, Mittal, R, Zampini, A, Fascelli, M, Murthy, PB, Haber, GP, Lee, BH. Large Single Institution Comparison of Perioperative Outcomes and Complications of Open Radical Cystectomy, Intracorporeal Robot-Assisted Radical Cystectomy and Robotic Extracorporeal Approach. Journal of Urology 203(3):512-521, 2020. e-Pub 2020. PMID: 31580189.
- Khanna, A, Saarela, O, Lawson, K, Finelli, A, Haber, GP, Lee, BH, Abouassaly, R. Hospital quality metrics for radical cystectomy: disease specific and correlated to mortality outcomes. Journal of Urology 202(3):490-497, 2019. e-Pub 2019. PMID: 31009290.
- Koshkin, VS, Garcia, JA, Reynolds, JP, Elson, P, Magi-Galluzzi, C, McKenney, J, Isse, K, Bishop, E, Saunders, LR, Balyimez, A, Rashid, S, Hu, M, Stephenson, AJ, Fergany, A, Lee, BH, Haber, GP, Dowlati, A, Gilligan, TD, Ornstein, MC, Rini, BI, Abazeed, ME, Mian, OY, Grivas, PD. Transcriptomic and protein analysis of small-cell bladder cancer (SCBC) Identifies prognostic biomarkers and DLL3 as a relevant therapeutic target. Clinical Cancer Research 25(1):210-221, 2019. e-Pub 2019. PMID: 30327311.
- Almassi, N, Gao, T, Lee, BH, Stein, RJ, Haber, GP, Ornstein, MC, Rini, BI, Gilligan, TD, Garcia, JA, Stephenson, AJ, Grivas, PD. Impact of Neoadjuvant Chemotherapy on Pathologic Response in Patients With Upper Tract Urothelial Carcinoma Undergoing Extirpative Surgery. Clinical Genitourinary Cancer 16(6):e1237-e1242, 2018. e-Pub 2018. PMID: 30217764.
- Parsai, S, Cherian, S, Berglund, RK, Lee, BH, Kolar, M, Nagle-Hernan, N, Wilkinson, A, Ciezki, J. Principles and practice of high-dose rate penile brachytherapy: planning and delivery techniques. Practical radiation oncology 8(6):e386-e391, 2018. e-Pub 2018. PMID: 29890234.
- Emamekhoo, H, Dhillon, P, Gopalakrishnan, D, Elson, P, Stephenson, AJ, Magi-Galluzzi, C, McKenney, J, Harper, H, Haber, GP, Kaouk, JH, Lee, BH, Fergany, A, Berglund, RK, Gong, MC, Stein, RJ, Krishnamurthi, V, Gilligan, TD, Ornstein, MC, Rini, BI, Garcia, JA, Grivas, PD. Prognostic Factors and Risk Stratification in Invasive Upper Tract Urothelial Carcinoma. Clinical Genitourinary Cancer 16(4):e751-e760, 2018. e-Pub 2018. PMID: 29551583.
- Isharwal, S, Huang, HY, Nanjangud, GJ, Audenet, F, Chen, YB, Gopalan, A, Fine, S, Tickoo, S, Lee, BH, Iyer, G, Chadalavada, K, Rosenberg, JE, Bajorin, D, Herr, HW, Donat, MS, Dalbagni, G, Bochner, BH, Solit, DB, Reuter, V, Al Ahmadie, H. Intratumoral heterogeneity of ERBB2 amplification and HER2 expression in micropapillary urothelial carcinoma. Human Pathology 77:63-69, 2018. e-Pub 2018. PMID: 29601842.
- Zabor, EC, Furberg, H, Lee, BH, Campbell, S, Lane, BR, Thompson, RH, Antonio, EC, Noyes, SL, Zaid, H, Jaimes, EA, Russo, P. Long-Term Renal Function Recovery following Radical Nephrectomy for Kidney Cancer. Journal of Urology 199(4):921-926, 2018. e-Pub 2018. PMID: 29066363.
- Zahoor, H, Elson, P, Stephenson, AJ, Haber, GP, Kaouk, JH, Fergany, A, Lee, BH, Koshkin, VS, Ornstein, MC, Gilligan, TD, Garcia, JA, Rini, BI, Grivas, PD. Patient Characteristics, Treatment Patterns and Prognostic Factors in Squamous Cell Bladder Cancer. Clinical Genitourinary Cancer 16(2):e437-e442, 2018. e-Pub 2018. PMID: 29154041.
- Lee, BH, Zabor, EC, Tennenbaum, D, Furberg, H, Benfante, N, Coleman, JA, Jaimes, EA, Russo, P. Renal function recovery after radical nephroureterectomy for upper tract urothelial carcinoma. World journal of urology 36(2):257-263, 2018. e-Pub 2018. PMID: 29209771.
- Bagrodia, A, Sukhu, R, Winer, AG, Levy, E, Vacchio, M, Lee, BH, Pietzak, E, Donahue, TF, Cha, EK, Iyer, G, Sjoberg, D, Vickers, A, Rosenberg, JE, Bajorin, D, Dalbagni, G, Bochner, BH. Incidence and Effect of Thromboembolic Events in Radical Cystectomy Patients Undergoing Preoperative Chemotherapy for Muscle-invasive Bladder Cancer. Clinical Genitourinary Cancer 16(1):e113-e120, 2018. e-Pub 2018. PMID: 28866245.
- Lee, BH, Feifer, A, Feuerstein, MA, Benfante, N, Kou, L, Yu, C, Kattan, MW, Russo, P. Validation of a Postoperative Nomogram Predicting Recurrence in Patients with Conventional Clear Cell Renal Cell Carcinoma. European Urology Focus 4(1):100-105, 2018. e-Pub 2018. PMID: 28753780.
- Bagrodia, A, Lee, BH, Lee, W, Cha, EK, Sfakianos, JP, Iyer, G, Pietzak, E, Gao, SP, Zabor, EC, Ostrovnaya, I, Kaffenberger, S, Syed, A, Arcila, ME, Chaganti, RS, Kundra, R, Eng, J, Hreiki, J, Vacic, V, Arora, K, Oschwald, D, Berger, MF, Bajorin, D, Bains, MS, Schultz, N, Reuter, V, Sheinfeld, J, Bosl, GJ, Al Ahmadie, H, Solit, DB, Feldman, DR. Genetic determinants of cisplatin resistance in patients with advanced germ cell tumors. Journal of Clinical Oncology 34(33):4000-4007, 2016. e-Pub 2016. PMID: 27646943.
- Bagrodia, A, Cha, EK, Sfakianos, JP, Zabor, EC, Bochner, BH, Al-Ahmadie, HA, Solit, DB, Coleman, JA, Iyer, G, Scott, SN, Shah, R, Ostrovnaya, I, Lee, B, Desai, NB, Ren, Q, Rosenberg, JE, Dalbagni, G, Bajorin, DF, Reuter, VE, Berger, MF, Collaborators. Genomic Biomarkers for the Prediction of Stage and Prognosis of Upper Tract Urothelial Carcinoma. Journal of Urology 195(6):1684-1689, 2016. e-Pub 2016. PMID: 26778714.
- Al Ahmadie, H, Iyer, G, Lee, BH, Scott, SN, Mehra, R, Bagrodia, A, Jordan, EJ, Gao, SP, Ramirez, R, Cha, EK, Desai, NB, Zabor, EC, Ostrovnaya, I, Gopalan, A, Chen, YB, Fine, S, Tickoo, S, Gandhi, A, Hreiki, J, Viale, A, Arcila, ME, Dalbagni, G, Rosenberg, JE, Bochner, BH, Bajorin, D, Berger, MF, Reuter, V, Taylor, BS, Solit, DB. Frequent somatic CDH1 loss-of-function mutations in plasmacytoid variant bladder cancer. Nature Genetics 48(4):356-358, 2016. e-Pub 2016. PMID: 26901067.
- Chang, MT, Asthana, S, Gao, SP, Lee, BH, Chapman, JS, Kandoth, C, Gao, J, Socci, ND, Solit, DB, Olshen, A, Schultz, N, Taylor, BS. Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. Nature biotechnology 34(2):155-163, 2016. e-Pub 2016. PMID: 26619011.
- Zabor, EC, Furberg, H, Mashni, J, Lee, BH, Jaimes, EA, Russo, P. Factors associated with recovery of renal function following radical nephrectomy for kidney neoplasms. Clinical Journal of the American Society of Nephrology 11(1):101-107, 2016. e-Pub 2016. PMID: 26500248.
- Lee, BH, Kibel, AS, Ciezki, J, Klein, EA, Reddy, C, Yu, C, Kattan, MW, Stephenson, AJ. Are biochemical recurrence outcomes similar after radical prostatectomy and radiation therapy? Analysis of prostate cancer-specific mortality by nomogram-predicted risks of biochemical recurrence. European urology 67(2):204-209, 2015. e-Pub 2015. PMID: 25294696.
- Bhasin, JM, Lee, BH, Matkin, L, Taylor, MG, Hu, B, Xu, Y, Magi-Galluzzi, C, Klein, EA, Ting, AH. Methylome-wide Sequencing Detects DNA Hypermethylation Distinguishing Indolent from Aggressive Prostate Cancer. Cell Reports 13(10):2135-2146, 2015. e-Pub 2015. PMID: 26628371.
- Lee, BH, Taylor, MG, Robinet, P, Smith, JD, Schweitzer, J, Sehayek, E, Falzarano, S, Magi-Galluzzi, C, Klein, EA, Ting, AH. Dysregulation of cholesterol homeostasis in human prostate cancer through loss of ABCA1. Cancer Research 73(3):1211-1218, 2013. e-Pub 2013. PMID: 23233737.
- Diaz, EC, Susan, S, Patel, NS, Lee, BH, Cabelin, M, Aron, M, Stein, RJ. Laparoscopic-assisted vesicocalicostomy for severe pelvi-ureteral stricture disease. Journal of the Society of Laparoendoscopic Surgeons 17(3):468-470, 2013. e-Pub 2013. PMID: 24018089.
- Long, JA, Lee, BH, Eyraud, R, Autorino, R, Hillyer, S, Stein, RJ, Kaouk, JH, Haber, GP. Robotic partial nephrectomy: imperative vs. elective indications. Urology 80(4):833-837, 2012. e-Pub 2012. PMID: 23021664.
- Long, JA, Lee, BH, Guillotreau, J, Autorino, R, Laydner, H, Yakoubi, R, Rizkala, E, Stein, RJ, Kaouk, JH, Haber, GP. Real-time robotic transrectal ultrasound navigation during robotic radical prostatectomy: initial clinical experience. Urology 80(3):608-613, 2012. e-Pub 2012. PMID: 22925237.
- Simmons, MN, Hillyer, S, Lee, BH, Fergany, A, Kaouk, JH, Campbell, S. Diameter-axial-polar nephrometry: integration and optimization of R.E.N.A.L. and centrality index scoring systems. Journal of Urology 188(2):384-390, 2012. e-Pub 2012. PMID: 22698624.
- Simmons, MN, Hillyer, S, Lee, BH, Fergany, A, Kaouk, JH, Campbell, S. Nephrometry score is associated with volume loss and functional recovery after partial nephrectomy. Journal of Urology 188(1):39-44, 2012. e-Pub 2012. PMID: 22578726.
- Long, JA, Yakoubi, R, Lee, BH, Guillotreau, J, Autorino, R, Laydner, H, Eyraud, R, Stein, RJ, Kaouk, JH, Haber, GP. Robotic versus laparoscopic partial nephrectomy for complex tumors: comparison of perioperative outcomes. European urology 61(6):1257-1262, 2012. e-Pub 2012. PMID: 22464543.
- Simmons, MN, Hillyer, S, Lee, BH, Fergany, A, Kaouk, JH, Campbell, S. Functional recovery after partial nephrectomy: effects of volume loss and ischemic injury. Journal of Urology 187(5):1667-1673, 2012. e-Pub 2012. PMID: 22425124.
- Xu, Y, Hu, B, Choi, AJ, Gopalan, B, Lee, BH, Kalady, MF, Church, J, Ting, AH. Unique DNA methylome profiles in CpG island methylator phenotype colon cancers. Genome research 22(2):283-291, 2012. e-Pub 2012. PMID: 21990380.
- Diaz, EC, Susan, S, Patel, NS, Lee, BH, Cabelin, M, Aron, M, Stein, RJ. Laparoscopic-assisted vesicocalicostomy for severe pelvi-ureteral stricture disease. Journal of the Society of Laparoendoscopic Surgeons 16(1):163-165, 2012. e-Pub 2012. PMID: 22906348.
- Patel, AR, Lee, BH, Campbell, S, Zhou, M, Fergany, A. Bilateral synchronous sporadic renal tumors: pathologic concordance and clinical implications. Urology 78(5):1095-1099, 2011. e-Pub 2011. PMID: 21937095.
- Lee, BH, Hernandez, AV, Zaytoun, O, Berglund, RK, Gong, MC, Jones, JS. Utility of percent free prostate-specific antigen in repeat prostate biopsy. Urology 78(2):386-391, 2011. e-Pub 2011. PMID: 21683989.
- Lee, BH, Moussa, AS, Li, J, Fareed, K, Jones, JS. Percentage of free prostate-specific antigen: implications in modern extended scheme prostate biopsy. Urology 77(4):899-903, 2011. e-Pub 2011. PMID: 21146865.
- Lin, J, Haffner, MC, Zhang, Y, Lee, BH, Brennen, WN, Britton, J, Kachhap, S, Shim, JS, Liu, JO, Nelson, WG, Yegnasubramanian, S, Carducci, M. Disulfiram is a DNA demethylating agent and inhibits prostate cancer cell growth. Prostate 71(4):333-343, 2011. e-Pub 2011. PMID: 20809552.
- Yan, H, Choi, AJ, Lee, BH, Ting, AH. Identification and functional analysis of epigenetically silenced micrornas in colorectal cancer cells. PLoS one 6(6), 2011. e-Pub 2011. PMID: 21698188.
- Serre, D, Lee, BH, Ting, AH. MBD-isolated genome sequencing provides a high-throughput and comprehensive survey of DNA methylation in the human genome. Nucleic acids research 38(2):391-399, 2009. e-Pub 2009. PMID: 19906696.
- Ting, AH, Suzuki, H, Cope, L, Schuebel, KE, Lee, BH, Toyota, M, Imai, K, Shinomura, Y, Tokino, T, Baylin, SB. A requirement for DICER to maintain full promoter CpG island hypermethylation in human cancer cells. Cancer Research 68(8):2570-2575, 2008. e-Pub 2008. PMID: 18413723.
- Nelson, WG, Yegnasubramanian, S, Agoston, AT, Bastian, PJ, Lee, BH, Nakayama, M, DeMarzo, AM. Abnormal DNA methylation, epigenetics, and prostate cancer. Frontiers in Bioscience 12(11):4254-4266, 2007. e-Pub 2007. PMID: 17485372.
- Lee, BH, Yegnasubramanian, S, Lin, X, Nelson, WG. Procainamide is a specific inhibitor of DNA methyltransferase 1. Journal of Biological Chemistry 280(49):40749-40756, 2005. e-Pub 2005. PMID: 16230360.
- Lin, X, Tascilar, M, Lee, WH, Vles, WJ, Lee, BH, Veeraswamy, R, Asgari, K, Freije, D, Van Rees, B, Gage, W, Bova, GS, Isaacs, W, Brooks, JD, DeWeese, TL, DeMarzo, AM, Nelson, WG. GSTP1 CpG island hypermethylation is responsible for the absence of GSTP1 expression in human prostate cancer cells. American Journal of Pathology 159(5):1815-1826, 2001. e-Pub 2001. PMID: 11696442.
Other Articles
- Lotan Y, Agarwal P, Black P, Dickstein R, Kamat AM, Lee B, Narayan VM, Porten S, Psutka SP, Smith AK, Svatek RS, Williams SB, Woldu S Standardization of the evaluation and surveillance of patients with BCG unresponsive high grade non-muscle invasive bladder cancer clinical trials. Urologic Oncology: Seminars and Original Investigations, 2024. PMID: 38307803.
- Campbell, R, Lee, BH Editorial Comment. Urology 171:139, 2023. PMID: 36610777.
- Knorr, JM, Campbell, R, Cockrum, J, Dalton, JE, Murthy, PB, Berglund, RK, Cullen, J, Weight, C, Almassi, N, Abouassaly, R, Kaouk, JH, Haber, GP, Lee, BH AUTHOR REPLY. Urology 163:184, 2022. PMID: 35636850.
- Janssen, GW, Ramkumar, R, Lee, BH, van der Heijden, AG Orthotopic urinary diversions after radical cystectomy for bladder cancer. Current opinion in urology 31(6):580-585, 2021. PMID: 34175877.
- Lee, BH EDITORIAL COMMENT. Urology 156:108-109, 2021. PMID: 34758551.
- Murthy, PB, Campbell, R, Lee, BH Intracorporeal Urinary Diversion in Robotic Radical Cystectomy. Urologic Clinics of North America 48(1):51-70, 2021. PMID: 33218594.
- Murthy, PB, Bryk, DJ, Lee, BH, Haber, GP Robotic radical cystectomy with intracorporeal urinary diversion. Translational Andrology and Urology 9(2):942-948, 2020. PMID: 32420210.
- Lee, BH EDITORIAL COMMENT. Urology 133:161-162, 2019. PMID: 31706415.
- Lee, BH Commentary on: "Comprehensive molecular characterization of papillary renal-cell carcinoma." Cancer Genome Atlas Research Network.: N Engl J Med. 2016 Jan 14;374(2):135-45. Urologic Oncology: Seminars and Original Investigations 35(9):578-579, 2017. PMID: 28780132.
- Lee, BH Commentary on: "Clonal evolution of chemotherapy-resistant urothelial carcinoma." Faltas BM, Prandi D, Tagawa ST, Molina AM, Nanus DM, Sternberg C, Rosenberg J, Mosquera JM, Robinson B, Elemento O, Sboner A, Beltran H, Demichelis F, Rubin MA.: Nat Genet. 2016 Oct 17. http://dx.doi.org/10.1038/ng.3692. Urologic Oncology: Seminars and Original Investigations 35(9):577-578, 2017. PMID: 28780131.
- Lee, BH Commentary on: "Inherited DNA-repair gene mutations in men with metastatic prostate cancer." Pritchard CC, Mateo J, Walsh MF, De Sarkar N, Abida W, Beltran H, Garofalo A, Gulati R, Carreira S, Eeles R, Elemento O, Rubin MA, Robinson D, Lonigro R, Hussain M, Chinnaiyan A, Vinson J, Filipenko J, Garraway L, Taplin ME, AlDubayan S, Han GC, Beightol M, Morrissey C, Nghiem B, Cheng HH, Montgomery B, Walsh T, Casadei S, Berger M, Zhang L, Zehir A, Vijai J, Scher HI, Sawyers C, Schultz N, Kantoff PW, Solit D, Robson M, Van Allen EM, Offit K, de Bono J, Nelson PS. N Engl J Med. 2016 Aug 4;375(5):443-53. Urologic Oncology: Seminars and Original Investigations 35(9):575-576, 2017. PMID: 28789927.
- Lee, BH Commentary on: "Redirecting abiraterone metabolism to fine-tune prostate cancer anti-androgen therapy." Li Z, Alyamani M, Li J, Rogacki K, Abazeed M, Upadhyay SK, Balk SP, Taplin ME, Auchus RJ, Sharifi N. Nature. 2016 May 25;533(7604):547-51. Urologic Oncology: Seminars and Original Investigations 35(9):576, 2017. PMID: 28789926.
- Lee, BH Commentary on: "An integrated metabolic atlas of clear cell renal cell carcinoma." Hakimi AA, Reznik E, Lee CH, Creighton CJ, Brannon AR, Luna A, Aksoy BA, Liu EM, Shen R, Lee W, Chen Y, Stirdivant SM, Russo P, Chen YB, Tickoo SK, Reuter VE, Cheng EH, Sander C, Hsieh JJ.: Cancer Cell. 2016 Jan 11;29(1):104-16. Urologic Oncology: Seminars and Original Investigations 35(9):579-580, 2017. PMID: 28789930.
- Lee, BH Commentary on: "Comprehensive transcriptional analysis of early-stage urothelial carcinoma." Hedegaard J, Lamy P, Nordentoft I, Algaba F, Høyer S, Ulhøi BP, Vang S, Reinert T, Hermann GG, Mogensen K, Thomsen MB, Nielsen MM, Marquez M, Segersten U, Aine M, Höglund M, Birkenkamp-Demtröder K, Fristrup N, Borre M, Hartmann A, Stöhr R, Wach S, Keck B, Seitz AK, Nawroth R, Maurer T, Tulic C, Simic T, Junker K, Horstmann M, Harving N, Petersen AC, Calle ML, Steyerberg EW, Beukers W, van Kessel KE, Jensen JB, Pedersen JS, Malmström PU, Malats N, Real FX, Zwarthoff EC, Ørntoft TF, Dyrskjøt L. Cancer Cell. 2016 Jul 11;30(1):27-42. Urologic Oncology: Seminars and Original Investigations 35(9):576-577, 2017. PMID: 28789929.
- Lee, BH, Iyer, G, Al Ahmadie, H Editorial Comment. Urology 102:147, 2017. PMID: 28034532.
- Patel, AR, Lee, BH, Campbell, S, Fergany, A, Zhou, M Reply. Urology 78(5):1099-1100, 2011.
Editorials
- Ting AH, Lee BH. 5mC: what goes on must come off. Nat Rev Mol Cell Biol 23(5):306, 2022. PMID: 35217851.
Book Chapters
- Lee BH, Carroll PR, Klein EA. Changing Landscape of Prostate Cancer Favoring Low-Risk Prostate Cancer: Implications for Active Surveillance Versus Focal Therapy. In: Imaging and Focal Therapy of Early Prostate Cancer. 1. Humana Press, 17-36, 2012.
- Campbell SC, Lee BH. Management of Small Renal Masses: Donating Kidneys to Your Local Pathologist is Not Advised. In: Emerging Cancer Therapeutics. 1. Demos Medical Publishing, 57-72, 2011.
Letters to the Editor
- Nunez-Rodriguez E, Lee BH, Cata JP. Understanding regional anesthesia's impact on non-muscle invasive bladder cancer oncological outcomes. Reg Anesth Pain Med, 2025.
- Zhang, JH, Ericson, K, Thomas, LJ, Knorr, JM, Khanna, A, Crane, A, Mittal, R, Zampini, A, Fascelli, M, Murthy, PB, Haber, GP, Lee, BH. Reply by Authors. Journal of Urology 203: 521, 2020.
Patient Reviews
CV information above last modified May 07, 2025