Christopher J. Logothetis, M.D.
Department of Genitourinary Medical Oncology, Division of Cancer Medicine
Present Title & Affiliation
Primary Appointment
Professor, Department of Genitourinary Medical Oncology, Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX
Roy M. and Phyllis Gough Huffington Clinical Research in Urologic Oncology Distinguished Chair, Department of Genitourinary Medical Oncology, Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX
Director, Department of The David H. Koch Center for Applied Research of Genitourinary Cancers, The University of Texas MD Anderson Cancer Center, Houston, TX
Education & Training
Degree-Granting Education
1974 | University of Athens School of Medicine, Athens, GRC, MD, Medicine |
Postgraduate Training
1977-1979 | Fellow, The University of Texas MD Anderson Cancer Center, Houston, TX |
1975-1977 | Clinical Residency, Cook County Hospital, Chicago, IL |
1974-1975 | Clinical Internship, Cook County Hospital, Chicago, IL |
Board Certifications
1981 | Medical Oncology Subspecialty Board |
1978 | American Board of Internal Medicine |
Experience & Service
Academic Appointments
Chief, Section of Genitourinary Medical Oncology, Department of Genitourinary Medical Oncology, Division of Cancer Medicine, The University of Texas M. D. Anderson Cancer Center, Houston, TX, 1986 - 1993
Administrative Appointments/Responsibilities
Director, Department of Genitourinary Cancer Center, The University of Texas MD Anderson Cancer Center, Houston, TX, 2002 - 2015
Department Chair, Department of Genitourinary Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, 1993 - 2019
Other Appointments/Responsibilities
Expert Foreign Referee, Athens Medical School Review Committee, Athens, 2014 - Present
Institutional Committee Activities
Internal Advisory Board Member, MD Anderson Kidney SPORE, 2017 - Present
Internal Advisory Board Member, MD Anderson Breast Cancer SPORE, 2016 - Present
Internal Advisory Board Member, Brain Tumor SPORE, 2013 - Present
Member, Institutional Research Executive Committee (IREC), 2013 - Present
Member, Moon Shots Program Steering Committee, 2012 - Present
Chair, Epidemiology Chair Search Committee, 2007 - Present
Member, DoCM Advisory Committee, 1993 - Present
Member, DoCM Executive Council, 1993 - Present
Endowed Positions
Bessie McGoldrick Professorship in Clinical Cancer Research, Department of unknown, Division of Cancer Medicine, The University of Texas M. D. Anderson Cancer Center, Houston, TX, 1994 - 2002
Consultantships
Consultant, Janssen Pharmaceuticals, Philadelphia, PA, 2017 - 2017
Consultant, Churchill Pharmaceuticals, Dallas, TX, 2017 - 2017
Advisor, Sanofi US Services Inc, Boston, MA, 2016 - 2016
Advisor, Roswell Park Cancer Institute, Buffalo, NY, 2016 - 2016
Consultant, Global Medical Affairs Oncology (Bayer), Whippany, NJ, 2016 - 2016
Consultant, Northwestern Memorial Hospital, Chicago, IL, 2016 - 2016
Consultant, Arno Therapeutics, Santa Monica, CA, 2016 - 2016
Advisor, Sanofi US Services Inc, New Orleans, LA, 2016 - 2016
Consultant, Astellas Pharma US, Inc and Medivation, Inc, San Francisco, CA, 2016 - 2016
Advisor, Sanofi Oncology, Boston, MA, 2015 - 2015
Consultant, Churchill Pharmaceuticals, Chicago, IL, 2015 - 2015
Consultant, Astellas Medical Affairs, Americas and Medivation, Inc, Washington, DC, 2015 - 2015
Consultant, Clovis Oncology, Inc, Washington, DC, 2015 - 2015
Consultant, Moffitt Cancer Center, Tampa, FL, 2015 - 2015
Consultant, Astellas Scientific and Medical Affairs, Inc. and Medivation, Inc, Rosemont, IL, 2014 - 2014
Consultant, National Cancer Institute, Rockville, MD, 2014 - 2014
Consultant, Bayer Oncology, Whippany, NJ, 2014 - 2014
Consultant, Janssen Pharmaceutica NV, Lisbon, Portugal, 2014 - 2014
Consultant, Helsinn Healthcare SA, Switzerland, 2014 - 2014
Consultant, Millennium, The Takeda Oncology Company, Boston, MA, 2014 - 2014
Consultant, Novartis, Prague, Czech Republic, 2014 - 2014
Consultant, Bristol-Myers Squibb, Jersey City, NJ, 2014 - 2014
Honors & Awards
2021 | Prostate Cancer Medical Professional of the Year Award, Texas US TOO |
2019 | Mount Sinai Hospital Lifetime Achievement Award, Icahn School of Medicine |
2015 | The Finneran Family Prize in Translational Research, William B. Finneran |
2015 | Division of Cancer Medicine Hematology/Oncology Fellowship Program Distinguished Alumnus Award, The University of Texas MD Anderson Cancer Center |
2015 | Charles A. LeMaistre, M.D., Outstanding Achievement Award in Cancer, The University of Texas MD Anderson Cancer Center |
2014 | PCF-Special Challenge Award, Prostate Cancer Foundation |
2012 | Division of Cancer Medicine John Mendelsohn Lifetime Scientific Achievement Award, The University of Texas MD Anderson Cancer Center |
2011 | Director's Service Award, National Cancer Institute |
2011 | Challenge Award, Prostate Cancer Foundation |
2010 | Division of Cancer Medicine Hematology/Oncology Fellowship Program Teaching Department of the Year, The University of Texas MD Anderson Cancer Center |
2005 | Donald S. Coffey Prostate Cancer Foundation Physician/Scientist Award, Prostate Cancer Foundation |
1998 | The University Cancer Foundation Faculty Achievement Award in Patient Care, The University of Texas MD Anderson Cancer Center |
1993 | CaP CURE Award, The Prostate Cancer Foundation |
1992 | Excellence in Teaching Clinical Oncology Award, The University of Texas M. D. Anderson Cancer Center Medical Oncology Fellows |
1979 | Clifton D. Howe Fellowship Achievement Award, The University of Texas MD Anderson Cancer Center |
Professional Memberships
Selected Publications
Peer-Reviewed Articles
- Yu G, Corn PG, Mak CSL, Liang X, Zhang M, Troncoso P, Song JH, Lin SC, Song X, Liu J, Zhang J, Logothetis CJ, Melancon MP, Panaretakis T, Wang G, Lin SH. Prostate cancer-induced endothelial-cell-to-osteoblast transition drives immunosuppression in the bone-tumor microenvironment through Wnt pathway-induced M2 macrophage polarization. Proc Natl Acad Sci U S A 121(33):e2402903121, 2024. e-Pub 2024. PMID: 39102549.
- Fizazi K, Le Teuff G, Fléchon A, Pagliaro L, Mardiak J, Geoffrois L, Laguerre B, Chevreau C, Delva R, Rolland F, Theodore C, Roubaud G, Gravis G, Eymard JC, Cancel M, Juzyna B, Reckova M, Naoun N, Logothetis C, Culine S. Personalized Chemotherapy on the Basis of Tumor Marker Decline in Poor-Prognosis Germ-Cell Tumors: Updated Analysis of the GETUG-13 Phase III Trial. J Clin Oncol:JCO2301960. e-Pub 2024. PMID: 39167741.
- Aparicio AM, Tidwell RSS, Yadav SS, Chen JS, Zhang M, Liu J, Guo S, Pilié PG, Yu Y, Song X, Vundavilli H, Jindal S, Zhu K, Viscuse PV, Lebenthal JM, Hahn AW, Soundararajan R, Corn PG, Zurita-Saavedra A, Subudhi SK, Zhang J, Wang W, Huff C, Troncoso P, Allison JP, Sharma P, Logothetis CJ. A Modular Trial of Androgen Signaling Inhibitor Combinations Testing a Risk-Adapted Strategy in Patients with Metastatic Castration-Resistant Prostate Cancer. Clin Cancer Res 30(13):2751-2763, 2024. PMID: 38683200.
- Hahn AW, Tidwell RS, Pilie PG, Yu Y, Liu J, Surasi DS, Titus M, Zhang J, Venkatesh N, Panaretakis T, Gregg JR, Zurita AJ, Siddiqui BA, Corn PG, Subudhi SK, Msaouel P, Koutroumpakis E, Huff CD, Aparicio A, McQuade JL, Frigo DE, Logothetis CJ. Body composition as a determinant of the therapeutic index with androgen signaling inhibition. Prostate Cancer Prostatic Dis. e-Pub 2024. PMID: 39019979.
- Lin SC, Yu G, Corn PG, Damasco J, Lee YC, Song JH, Navone NM, Logothetis CJ, Melancon MP, Panaretakis T, Lin SH. Radium-223 Treatment Produces Prolonged Suppression of Resident Osteoblasts and Decreased Bone Mineral Density in Trabecular Bone in Osteoblast Reporter Mice. Cancers (Basel) 16(14), 2024. e-Pub 2024. PMID: 39061241.
- Koutroumpakis E, Patel R, Khadke S, Bedrosian A, Kumar A, Kong Y, Connell B, Upadhyay J, Dani SS, Hahn AW, Logothetis CJ, Al-Kindi S, Butler J, Nohria A, Ganatra S, Deswal A. Associations of SGLT-2i with Cardiorenal Outcomes Among Diabetics with Prostate Cancer on Hormone Therapy. Res Sq, 2024. e-Pub 2024. PMID: 39108488.
- Hahn AW, Manyam GC, Chapin BF, Zhang M, Yu Y, Pettaway CA, Chery L, Pisters LL, Ward JF, Gregg JR, Papadopoulos J, Kamat AM, Lozano M, Hoang A, Broom B, Wang X, Huff CD, Logothetis CJ, Troncoso P, Pilié PG, Davis JW. A phase II trial of apalutamide for intermediate-risk prostate cancer and molecular correlates. BJU Int. e-Pub 2024. PMID: 38837608.
- Beckham TH, Rooney MK, Cifter G, Bernard V, McAleer MF, De BS, Tom MC, Perni S, Wang C, Swanson T, Tatsui CE, Alvarez-Breckenridge C, North R, Rhines LD, Tang C, Logothetis C, Amini B, Li J, Yeboa DN, Ghia AJ. Stereotactic radiosurgery for prostate cancer spine metastases: local control and fracture risk using a simultaneous integrated boost approach. J Neurosurg Spine:1-9. e-Pub 2024. PMID: 38875722.
- Anselmino N, Labanca E, Shepherd PDA, Dong J, Yang J, Song X, Nandakumar S, Kundra R, Lee C, Schultz N, Zhang J, Araujo JC, Aparicio AM, Subudhi SK, Corn PG, Pisters LL, Ward JF, Davis JW, Vazquez ES, Gueron G, Logothetis CJ, Futreal A, Troncoso P, Chen Y, Navone NM. Integrative molecular analyses of the MD Anderson prostate cancer patient-derived xenograft (MDA PCa PDX) series. Clin Cancer Res 30(10):2272-2285, 2024. e-Pub 2024. PMID: 38488813.
- Abida W, Hahn AW, Shore N, Agarwal N, Sieber P, Smith MR, Dorff T, Monk P, Rettig M, Patel R, Page A, Duff M, Xu R, Wang J, Barkund S, Pankov A, Wang A, Junttila MR, Multani PS, Daemen A, Chow Maneval E, Logothetis CJ, Morris MJ. Phase 1 Study of ORIC-101, a Glucocorticoid Receptor Antagonist, in Combination with Enzalutamide in Patients with Metastatic Castration-Resistant Prostate Cancer Progressing on Enzalutamide. Clin Cancer Res 30(6):1111-1120, 2024. e-Pub 2024. PMID: 38226958.
- Paindelli C, Parietti V, Barrios S, Shepherd P, Pan T, Wang WL, Satcher RL, Logothetis CJ, Navone N, Campbell MT, Mikos AG, Dondossola E. Bone mimetic environments support engineering, propagation, and analysis of therapeutic response of patient-derived cells, ex vivo and in vivo. Acta Biomater. e-Pub 2024. PMID: 38387748.
- Logothetis CJ, Hahn AW. Challenging the Prevailing Therapeutic Dogma for Prostate Cancer: The Case for an Overlap Syndrome. Eur Urol 85(1):3-7, 2024. e-Pub 2023. PMID: 37210287.
- Sakellakis MJ, Hahn AW, Ramachandran S, Zhang M, Hoang A, Song JH, Liu J, Wang F, Basu HS, Sheperd P, Wang X, Frigo DE, Lin SH, Panaretakis T, Zhang J, Navone N, Troncoso P, Logothetis CJ, Titus MA. Characterization of prostate cancer adrenal metastases: dependence upon androgen receptor signaling and steroid hormones. Prostate Cancer Prostatic Dis 26(4):751-758, 2023. e-Pub 2022. PMID: 36100698.
- Alhalabi O, Wilson N, Xiao L, Lin Y, Khandelwal J, Moussa MJ, Msaouel P, Navai N, Gao J, Kamat AM, Pilie P, Shah AY, Goswami S, Matin S, Kovitz C, Holla V, Guo C, Czerniak B, Logothetis C, Corn PG, Dinney CPN, Campbell MT, Hansel DE, Tannir NM, Siefker-Radtke AO. Comparative Effectiveness Analysis of Treatment Strategies for Surgically Resectable Neuroendocrine Carcinoma of the Urinary Tract. Eur Urol Oncol 6(6):611-620, 2023. e-Pub 2023. PMID: 37833193.
- Wang A, Shen J, Rodriguez AA, Saunders EJ, Chen F, Janivara R, Darst BF, Sheng X, Xu Y, Chou AJ, Benlloch S, Dadaev T, Brook MN, Plym A, Sahimi A, Hoffman TJ, Takahashi A, Matsuda K, Momozawa Y, Fujita M, Laisk T, Figuerêdo J, Muir K, Ito S, Liu X, Biobank Japan Project, Uchio Y, Kubo M, Kamatani Y, Lophatananon A, Wan P, Andrews C, Lori A, Choudhury PP, Schleutker J, Tammela TLJ, Sipeky C, Auvinen A, Giles GG, Southey MC, MacInnis RJ, Cybulski C, Wokolorczyk D, Lubinski J, Rentsch CT, Cho K, Mcmahon BH, Neal DE, Donovan JL, Hamdy FC, Martin RM, Nordestgaard BG, Nielsen SF, Weischer M, Bojesen SE, Røder A, Stroomberg HV, Batra J, Chambers S, Horvath L, Clements JA, Tilly W, Risbridger GP, Gronberg H, Aly M, Szulkin R, Eklund M, Nordstrom T, Pashayan N, Dunning AM, Ghoussaini M, Travis RC, Key TJ, Riboli E, Park JY, Sellers TA, Lin HY, Albanes D, Weinstein S, Cook MB, Mucci LA, Giovannucci E, Lindstrom S, Kraft P, Hunter DJ, Penney KL, Turman C, Tangen CM, Goodman PJ, Thompson IM, Hamilton RJ, Fleshner NE, Finelli A, Parent MÉ, Stanford JL, Ostrander EA, Koutros S, Beane Freeman LE, Stampfer M, Wolk A, Håkansson N, Andriole GL, Hoover RN, Machiela MJ, Sørensen KD, Borre M, Blot WJ, Zheng W, Yeboah ED, Mensah JE, Lu YJ, Zhang HW, Feng N, Mao X, Wu Y, Zhao SC, Sun Z, Thibodeau SN, McDonnell SK, Schaid DJ, West CML, Barnett G, Maier C, Schnoeller T, Luedeke M, Kibel AS, Drake BF, Cussenot O, Cancel-Tassin G, Menegaux F, Truong T, Koudou YA, John EM, Grindedal EM, Maehle L, Khaw KT, Ingles SA, Stern MC, Vega A, Gómez-Caamaño A, Fachal L, Rosenstein BS, Kerns SL, Ostrer H, Teixeira MR, Paulo P, Brandão A, Watya S, Lubwama A, Bensen JT, Butler EN, Mohler JL, Taylor JA, Kogevinas M, Dierssen-Sotos T, Castaño-Vinyals G, Cannon-Albright L, Teerlink CC, Huff CD, Pilie P, Yu Y, Bohlender RJ, Gu J, Strom SS, Multigner L, Blanchet P, Brureau L, Kaneva R, Slavov C, Mitev V, Leach RJ, Brenner H, Chen X, Holleczek B, Schöttker B, Klein EA, Hsing AW, Kittles RA, Murphy AB, Logothetis. Characterizing prostate cancer risk through multi-ancestry genome-wide discovery of 187 novel risk variants. Nat Genet 55(12):2065-2074, 2023. e-Pub 2023. PMID: 37945903.
- Yu G, Corn PG, Mak CSL, Liang X, Zhang M, Troncoso P, Song JH, Lin SC, Song X, Liu J, Zhang J, Logothetis CJ, Melancon MP, Panaretakis T, Wang G, Lin SH. Prostate cancer-induced endothelial-to-osteoblast transition generates an immunosuppressive bone tumor microenvironment. bioRxiv, 2023. e-Pub 2023. PMID: 38076845.
- Gentile E, Hahn AW, Song JH, Hoang A, Shepherd PDA, Ramachandran S, Navone NM, Efstathiou E, Titus M, Corn PG, Lin SH, Logothetis CJ, Panaretakis T. Monitoring Glucocorticoid Receptor in Plasma-derived Extracellular Vesicles as a Marker of Resistance to Androgen Receptor Signaling Inhibition in Prostate Cancer. Cancer Res Commun 3(12):2531-2543, 2023. PMID: 37930121.
- Viscuse PV, Slack-Tidwell RS, Zhang M, Rohra P, Zhu K, San Lucas FA, Konnick E, Pilie PG, Siddiqui B, Logothetis CJ, Corn P, Subudhi SK, Pritchard CC, Soundararajan R, Aparicio A. Evaluation of the Aggressive-Variant Prostate Cancer Molecular Signature in Clinical Laboratory Improvement Amendments (CLIA) Environments. Cancers (Basel) 15(24), 2023. e-Pub 2023. PMID: 38136389.
- Logotheti S, Papadaki E, Zolota V, Logothetis C, Vrahatis AG, Soundararajan R, Tzelepi V. Lineage Plasticity and Stemness Phenotypes in Prostate Cancer: Harnessing the Power of Integrated "Omics" Approaches to Explore Measurable Metrics. Cancers (Basel) 15(17), 2023. e-Pub 2023. PMID: 37686633.
- Hahn AW, Thoman W, Koutroumpakis E, Abdulla A, Subudhi SK, Aparicio A, Basen-Enngquist K, Logothetis CJ, Gilchrist SC. Cardiometabolic healthcare for men with prostate cancer: an MD Anderson Cancer Center experience. Cardiooncology 9(1):33, 2023. e-Pub 2023. PMID: 37705024.
- Vardaki I, Özcan SS, Fonseca P, Lin SH, Logothetis CJ, Yachnin J, Ullen A, Panaretakis T. Transcriptomic analysis of plasma exosomes provides molecular information of response to cabazitaxel treatment in men with metastatic castration-resistant prostate cancer. Prostate 83(10):950-961, 2023. e-Pub 2023. PMID: 37074030.
- Darst BF, Shen J, Madduri RK, Rodriguez AA, Xiao Y, Sheng X, Saunders EJ, Dadaev T, Brook MN, Hoffmann TJ, Muir K, Wan P, Le Marchand L, Wilkens L, Wang Y, Schleutker J, MacInnis RJ, Cybulski C, Neal DE, Nordestgaard BG, Nielsen SF, Batra J, Clements JA, Cancer BioResource AP, Grönberg H, Pashayan N, Travis RC, Park JY, Albanes D, Weinstein S, Mucci LA, Hunter DJ, Penney KL, Tangen CM, Hamilton RJ, Parent MÉ, Stanford JL, Koutros S, Wolk A, Sørensen KD, Blot WJ, Yeboah ED, Mensah JE, Lu YJ, Schaid DJ, Thibodeau SN, West CM, Maier C, Kibel AS, Cancel-Tassin G, Menegaux F, John EM, Grindedal EM, Khaw KT, Ingles SA, Vega A, Rosenstein BS, Teixeira MR, NC-LA PCaP Investigators, Kogevinas M, Cannon-Albright L, Huff C, Multigner L, Kaneva R, Leach RJ, Brenner H, Hsing AW, Kittles RA, Murphy AB, Logothetis CJ, Neuhausen SL, Isaacs WB, Nemesure B, Hennis AJ, Carpten J, Pandha H, De Ruyck K, Xu J, Razack A, Teo SH, Canary PASS Investigators, Newcomb LF, Fowke JH, Neslund-Dudas C, Rybicki BA, Gamulin M, Usmani N, Claessens F, Gago-Dominguez M, Castelao JE, Townsend PA, Crawford DC, Petrovics G, Casey G, Roobol MJ, Hu JF, Berndt SI, Van Den Eeden SK, Easton DF, Chanock SJ, Cook MB, Wiklund F, Witte JS, Eeles RA, Kote-Jarai Z, Watya S, Gaziano JM, Justice AC, Conti DV, Haiman CA. Evaluating approaches for constructing polygenic risk scores for prostate cancer in men of African and European ancestry. Am J Hum Genet 110(7):1200-1206, 2023. e-Pub 2023. PMID: 37311464.
- Mourkioti I, Polyzou A, Veroutis D, Theocharous G, Lagopati N, Gentile E, Stravokefalou V, Thanos DF, Havaki S, Kletsas D, Panaretakis T, Logothetis CJ, Stellas D, Petty R, Blandino G, Papaspyropoulos A, Gorgoulis VG. A GATA2-CDC6 axis modulates androgen receptor blockade-induced senescence in prostate cancer. J Exp Clin Cancer Res 42(1):187, 2023. e-Pub 2023. PMID: 37507762.
- Gregg JR, Kim J, Logothetis C, Hanash S, Zhang X, Manyam G, Muir K, UKGPCS Collaborative Group, Giles GG, Stanford JL, Berndt SI, Kogevinas M, Brenner H, Eeles RA, PRACTICAL Consortium, Wei P, Daniel CR. Coffee Intake, Caffeine Metabolism Genotype, and Survival Among Men with Prostate Cancer. Eur Urol Oncol 6(3):282-288, 2023. e-Pub 2022. PMID: 35995710.
- Gillessen S, Bossi A, Davis ID, de Bono J, Fizazi K, James ND, Mottet N, Shore N, Small E, Smith M, Sweeney CJ, Tombal B, Antonarakis ES, Aparicio AM, Armstrong AJ, Attard G, Beer TM, Beltran H, Bjartell A, Blanchard P, Briganti A, Bristow RG, Bulbul M, Caffo O, Castellano D, Castro E, Cheng HH, Chi KN, Chowdhury S, Clarke CS, Clarke N, Daugaard G, De Santis M, Duran I, Eeles R, Efstathiou E, Efstathiou J, Ekeke ON, Evans CP, Fanti S, Feng FY, Fonteyne V, Fossati N, Frydenberg M, George D, Gleave M, Gravis G, Halabi S, Heinrich D, Herrmann K, Higano C, Hofman MS, Horvath LG, Hussain M, Jereczek-Fossa BA, Jones R, Kanesvaran R, Kellokumpu-Lehtinen PL, Khauli RB, Klotz L, Kramer G, Leibowitz R, Logothetis C, Mahal B, Maluf F, Mateo J, Matheson D, Mehra N, Merseburger A, Morgans AK, Morris MJ, Mrabti H, Mukherji D, Murphy DG, Murthy V, Nguyen PL, Oh WK, Ost P, O'Sullivan JM, Padhani AR, Pezaro CJ, Poon DMC, Pritchard CC, Rabah DM, Rathkopf D, Reiter RE, Rubin MA, Ryan CJ, Saad F, Sade JP, Sartor O, Scher HI, Sharifi N, Skoneczna I, Soule H, Spratt DE, Srinivas S, Sternberg CN, Steuber T, Suzuki H, Sydes MR, Taplin ME, Tilki D, Türkeri L, Turco F, Uemura H, Uemura H, Ürün Y, Vale CL, van Oort I, Vapiwala N, Walz J, Yamoah K, Ye D, Yu EY, Zapatero A, Zilli T, Omlin A. Management of patients with advanced prostate cancer-metastatic and/or castration-resistant prostate cancer: report of the Advanced Prostate Cancer Consensus Conference (APCCC) 2022. Eur J Cancer 185:178-215, 2023. e-Pub 2023. PMID: 37003085.
- Halabi S, Yang Q, Roy A, Luo B, Araujo JC, Logothetis C, Sternberg CN, Armstrong AJ, Carducci MA, Chi KN, de Bono JS, Petrylak DP, Fizazi K, Higano CS, Morris MJ, Rathkopf DE, Saad F, Ryan CJ, Small EJ, Kelly WK. External Validation of a Prognostic Model of Overall Survival in Men With Chemotherapy-Naïve Metastatic Castration-Resistant Prostate Cancer. J Clin Oncol 41(15):JCO2202661, 2023. e-Pub 2023. PMID: 37040594.
- Darst BF, Shen J, Madduri RK, Rodriguez AA, Xiao Y, Sheng X, Saunders EJ, Dadaev T, Brook MN, Hoffmann TJ, Muir K, Wan P, Le Marchand L, Wilkens L, Wang Y, Schleutker J, MacInnis RJ, Cybulski C, Neal DE, Nordestgaard BG, Nielsen SF, Batra J, Clements JA, Australian Prostate Cancer BioResource, Grönberg H, Pashayan N, Travis RC, Park JY, Albanes D, Weinstein S, Mucci LA, Hunter DJ, Penney KL, Tangen CM, Hamilton RJ, Parent MÉ, Stanford JL, Koutros S, Wolk A, Sørensen KD, Blot WJ, Yeboah ED, Mensah JE, Lu YJ, Schaid DJ, Thibodeau SN, West CM, Maier C, Kibel AS, Cancel-Tassin G, Menegaux F, John EM, Grindedal EM, Khaw KT, Ingles SA, Vega A, Rosenstein BS, Teixeira MR, NC-LA PCaP Investigators, Kogevinas M, Cannon-Albright L, Huff C, Multigner L, Kaneva R, Leach RJ, Brenner H, Hsing AW, Kittles RA, Murphy AB, Logothetis CJ, Neuhausen SL, Isaacs WB, Nemesure B, Hennis AJ, Carpten J, Pandha H, De Ruyck K, Xu J, Razack A, Teo SH, Canary PASS Investigators, Newcomb LF, Fowke JH, Neslund-Dudas C, Rybicki BA, Gamulin M, Usmani N, Claessens F, GagoDominguez M, Castelao JE, Townsend PA, Crawford DC, Petrovics G, Casey G, Roobol MJ, Hu JF, Berndt SI, Van Den Eeden SK, Easton DF, Chanock SJ, Cook MB, Wiklund F, Witte JS, Eeles RA, Kote-Jarai Z, Watya S, Gaziano JM, Justice AC, Conti DV, Haiman CA. Evaluating Approaches for Constructing Polygenic Risk Scores for Prostate Cancer in Men of African and European Ancestry. medRxiv, 2023. e-Pub 2023. PMID: 37292833.
- Gillessen S, Bossi A, Davis ID, de Bono J, Fizazi K, James ND, Mottet N, Shore N, Small E, Smith M, Sweeney C, Tombal B, Antonarakis ES, Aparicio AM, Armstrong AJ, Attard G, Beer TM, Beltran H, Bjartell A, Blanchard P, Briganti A, Bristow RG, Bulbul M, Caffo O, Castellano D, Castro E, Cheng HH, Chi KN, Chowdhury S, Clarke CS, Clarke N, Daugaard G, De Santis M, Duran I, Eeles R, Efstathiou E, Efstathiou J, Ngozi Ekeke O, Evans CP, Fanti S, Feng FY, Fonteyne V, Fossati N, Frydenberg M, George D, Gleave M, Gravis G, Halabi S, Heinrich D, Herrmann K, Higano C, Hofman MS, Horvath LG, Hussain M, Jereczek-Fossa BA, Jones R, Kanesvaran R, Kellokumpu-Lehtinen PL, Khauli RB, Klotz L, Kramer G, Leibowitz R, Logothetis CJ, Mahal BA, Maluf F, Mateo J, Matheson D, Mehra N, Merseburger A, Morgans AK, Morris MJ, Mrabti H, Mukherji D, Murphy DG, Murthy V, Nguyen PL, Oh WK, Ost P, O'Sullivan JM, Padhani AR, Pezaro C, Poon DMC, Pritchard CC, Rabah DM, Rathkopf D, Reiter RE, Rubin MA, Ryan CJ, Saad F, Pablo Sade J, Sartor OA, Scher HI, Sharifi N, Skoneczna I, Soule H, Spratt DE, Srinivas S, Sternberg CN, Steuber T, Suzuki H, Sydes MR, Taplin ME, Tilki D, Türkeri L, Turco F, Uemura H, Uemura H, Ürün Y, Vale CL, van Oort I, Vapiwala N, Walz J, Yamoah K, Ye D, Yu EY, Zapatero A, Zilli T, Omlin A. Management of Patients with Advanced Prostate Cancer. Part I: Intermediate-/High-risk and Locally Advanced Disease, Biochemical Relapse, and Side Effects of Hormonal Treatment: Report of the Advanced Prostate Cancer Consensus Conference 2022. Eur Urol 83(3):267-293, 2023. e-Pub 2022. PMID: 36494221.
- Siddiqui BA, Chapin BF, Jindal S, Duan F, Basu S, Yadav SS, Gu AD, Espejo AB, Kinder M, Pettaway CA, Ward JF, Tidwell RSS, Troncoso P, Corn PG, Logothetis CJ, Knoblauch R, Hutnick N, Gottardis M, Drake CG, Sharma P, Subudhi SK. Immune and pathologic responses in patients with localized prostate cancer who received daratumumab (anti-CD38) or edicotinib (CSF-1R inhibitor). J Immunother Cancer 11(3), 2023. PMID: 36948506.
- Lin SC, Yu G, Lee YC, Song JH, Song X, Zhang J, Panaretakis T, Logothetis CJ, Komatsu Y, Yu-Lee LY, Wang G, Lin SH. Endothelial-to-osteoblast transition in normal mouse bone development. iScience 26(2):105994, 2023. e-Pub 2023. PMID: 36798441.
- Mossa F, Robesti D, Sumankalai R, Corey E, Titus M, Kang Y, Zhang J, Briganti A, Montorsi F, Vellano CP, Marszalek JR, Frigo DE, Logothetis CJ, Gujral TS, Dondossola E. Subtype and site specific-induced metabolic vulnerabilities in prostate cancer. Mol Cancer Res 21(1):51-61, 2023. e-Pub 2022. PMID: 36112348.
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- Labanca E, Bizzotto J, Sanchis P, Anselmino N, Yang J, Shepherd PDA, Paez A, Antico-Arciuch V, Lage-Vickers S, Hoang AG, Tang X, Raso MG, Titus M, Efstathiou E, Cotignola J, Araujo J, Logothetis C, Vazquez E, Navone N, Gueron G. Prostate cancer castrate resistant progression usage of non-canonical androgen receptor signaling and ketone body fuel. Oncogene 40(44):6284-6298, 2021. e-Pub 2021. PMID: 34584218.
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- Zhu M, Peng R, Liang X, Lan Z, Tang M, Hou P, Song JH, Mak CSL, Park J, Zheng SE, Huang A, Ma X, Chen R, Chang Q, Logothetis CJ, Jain AK, Lin SH, Katayama H, Hanash S, Wang G. P4HA2-induced prolyl hydroxylation suppresses YAP1-mediated prostate cancer cell migration, invasion, and metastasis. Oncogene 40(41):6049-6056, 2021. e-Pub 2021. PMID: 34471235.
- Subudhi SK, Siddiqui BA, Aparicio AM, Yadav SS, Basu S, Chen H, Jindal S, Tidwell RSS, Varma A, Logothetis CJ, Allison JP, Corn PG, Sharma P. Combined CTLA-4 and PD-L1 blockade in patients with chemotherapy-naïve metastatic castration-resistant prostate cancer is associated with increased myeloid and neutrophil immune subsets in the bone microenvironment. J Immunother Cancer 9(10), 2021. PMID: 34663638.
- Salzillo TC, Mawoneke V, Weygand J, Shetty A, Gumin J, Zacharias NM, Gammon ST, Piwnica-Worms D, Fuller GN, Logothetis CJ, Lang FF, Bhattacharya PK. Measuring the Metabolic Evolution of Glioblastoma throughout Tumor Development, Regression, and Recurrence with Hyperpolarized Magnetic Resonance. Cells 10(10), 2021. e-Pub 2021. PMID: 34685601.
- Grypari IM, Logotheti S, Zolota V, Troncoso P, Efstathiou E, Bravou V, Melachrinou M, Logothetis C, Tzelepi V. The protein arginine methyltransferases (PRMTs) PRMT1 and CARM1 as candidate epigenetic drivers in prostate cancer progression. Medicine (Baltimore) 100(36):e27094, 2021. PMID: 34516499.
- Bruinsma SM, Nieboer D, Roobol MJ, Bangma CH, Verbeek JFM, Gnanapragasam V, Van Hemelrijck M, Frydenberg M, Lee LS, Valdagni R, Logothetis C, Steyerberg EW. Risk-Based Selection for Active Surveillance: Results of the Movember Foundation's Global Action Plan Prostate Cancer Active Surveillance (GAP3) Initiative. J Urol 206(1):62-68, 2021. e-Pub 2021. PMID: 33617330.
- Pan T, Lin SC, Lee YC, Yu G, Song JH, Pan J, Titus M, Satcher RL, Panaretakis T, Logothetis C, Yu-Lee LY, Lin SH. Statins reduce castration-induced bone marrow adiposity and prostate cancer progression in bone. Oncogene 40(27):4592-4603, 2021. e-Pub 2021. PMID: 34127814.
- Hussain A, Tripathi A, Pieczonka C, Cope D, McNatty A, Logothetis C, Guise T. Bone health effects of androgen-deprivation therapy and androgen receptor inhibitors in patients with nonmetastatic castration-resistant prostate cancer. Prostate Cancer Prostatic Dis 24(2):290-300, 2021. e-Pub 2020. PMID: 33028943.
- Karunamuni RA, Huynh-Le MP, Fan CC, Thompson W, Eeles RA, Kote-Jarai Z, Muir K, Lophatananon A, UKGPCS collaborators, Schleutker J, Pashayan N, Batra J, APCB BioResource (Australian Prostate Cancer BioResource), Grönberg H, Walsh EI, Turner EL, Lane A, Martin RM, Neal DE, Donovan JL, Hamdy FC, Nordestgaard BG, Tangen CM, MacInnis RJ, Wolk A, Albanes D, Haiman CA, Travis RC, Stanford JL, Mucci LA, West CML, Nielsen SF, Kibel AS, Wiklund F, Cussenot O, Berndt SI, Koutros S, Sørensen KD, Cybulski C, Grindedal EM, Park JY, Ingles SA, Maier C, Hamilton RJ, Rosenstein BS, Vega A, IMPACT Study Steering Committee and Collaborators, Kogevinas M, Penney KL, Teixeira MR, Brenner H, John EM, Kaneva R, Logothetis CJ, Neuhausen SL, Razack A, Newcomb LF, Canary PASS Investigators, Gamulin M, Usmani N, Claessens F, Gago-Dominguez M, Townsend PA, Roobol MJ, Zheng W, Profile Study Steering Committee, Mills IG, Andreassen OA, Dale AM, Seibert TM, PRACTICAL Consortium. Additional SNPs improve risk stratification of a polygenic hazard score for prostate cancer. Prostate Cancer Prostatic Dis 24(2):532-541, 2021. e-Pub 2021. PMID: 33420416.
- Vardaki I, Corn P, Gentile E, Song JH, Madan N, Hoang A, Parikh N, Guerra L, Lee YC, Lin SC, Yu G, Santos E, Melancon MP, Troncoso P, Navone N, Gallick GE, Efstathiou E, Subudhi SK, Lin SH, Logothetis CJ, Panaretakis T. Radium-223 Treatment Increases Immune Checkpoint Expression in Extracellular Vesicles from the Metastatic Prostate Cancer Bone Microenvironment. Clin Cancer Res 27(11):3253-3264, 2021. e-Pub 2021. PMID: 33753455.
- Yu G, Shen P, Lee YC, Pan J, Song JH, Pan T, Lin SC, Liang X, Wang G, Panaretakis T, Logothetis CJ, Gallick GE, Yu-Lee LY, Lin SH. Multiple pathways coordinating reprogramming of endothelial cells into osteoblasts by BMP4. iScience 24(4):102388, 2021. e-Pub 2021. PMID: 33981975.
- Gerdtsson AS, Setayesh SM, Malihi PD, Ruiz C, Carlsson A, Nevarez R, Matsumoto N, Gerdtsson E, Zurita A, Logothetis C, Corn PG, Aparicio AM, Hicks J, Kuhn P. Large Extracellular Vesicle Characterization and Association with Circulating Tumor Cells in Metastatic Castrate Resistant Prostate Cancer. Cancers (Basel) 13(5), 2021. e-Pub 2021. PMID: 33801459.
- Gregg JR, Surasi DS, Childs A, Moll N, Ward JF, Kim J, Daniel CR, Logothetis C, Bathala T, Davis JW. The Association of Peri-Prostatic Fat and Grade Group Progression in Men with Localized Prostate Cancer on Active Surveillance. J Urol 205(1):101097JU0000000000001321, 2021. e-Pub 2020. PMID: 32718204.
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- Conti DV, Darst BF, Moss LC, Saunders EJ, Sheng X, Chou A, Schumacher FR, Olama AAA, Benlloch S, Dadaev T, Brook MN, Sahimi A, Hoffmann TJ, Takahashi A, Matsuda K, Momozawa Y, Fujita M, Muir K, Lophatananon A, Wan P, Le Marchand L, Wilkens LR, Stevens VL, Gapstur SM, Carter BD, Schleutker J, Tammela TLJ, Sipeky C, Auvinen A, Giles GG, Southey MC, MacInnis RJ, Cybulski C, Wokolorczyk D, Lubinski J, Neal DE, Donovan JL, Hamdy FC, Martin RM, Nordestgaard BG, Nielsen SF, Weischer M, Bojesen SE, Røder MA, Iversen P, Batra J, Chambers S, Moya L, Horvath L, Clements JA, Tilley W, Risbridger GP, Gronberg H, Aly M, Szulkin R, Eklund M, Nordström T, Pashayan N, Dunning AM, Ghoussaini M, Travis RC, Key TJ, Riboli E, Park JY, Sellers TA, Lin HY, Albanes D, Weinstein SJ, Mucci LA, Giovannucci E, Lindstrom S, Kraft P, Hunter DJ, Penney KL, Turman C, Tangen CM, Goodman PJ, Thompson IM, Hamilton RJ, Fleshner NE, Finelli A, Parent MÉ, Stanford JL, Ostrander EA, Geybels MS, Koutros S, Freeman LEB, Stampfer M, Wolk A, Håkansson N, Andriole GL, Hoover RN, Machiela MJ, Sørensen KD, Borre M, Blot WJ, Zheng W, Yeboah ED, Mensah JE, Lu YJ, Zhang HW, Feng N, Mao X, Wu Y, Zhao SC, Sun Z, Thibodeau SN, McDonnell SK, Schaid DJ, West CML, Burnet N, Barnett G, Maier C, Schnoeller T, Luedeke M, Kibel AS, Drake BF, Cussenot O, Cancel-Tassin G, Menegaux F, Truong T, Koudou YA, John EM, Grindedal EM, Maehle L, Khaw KT, Ingles SA, Stern MC, Vega A, Gómez-Caamaño A, Fachal L, Rosenstein BS, Kerns SL, Ostrer H, Teixeira MR, Paulo P, Brandão A, Watya S, Lubwama A, Bensen JT, Fontham ETH, Mohler J, Taylor JA, Kogevinas M, Llorca J, Castaño-Vinyals G, Cannon-Albright L, Teerlink CC, Huff CD, Strom SS, Multigner L, Blanchet P, Brureau L, Kaneva R, Slavov C, Mitev V, Leach RJ, Weaver B, Brenner H, Cuk K, Holleczek B, Saum KU, Klein EA, Hsing AW, Kittles RA, Murphy AB, Logothetis CJ, Kim J, Neuhausen SL, Steele L, Ding YC, Isaacs WB, Nemesure B, Hennis AJM, Carpten J, Pandha H, Michael A, De Ruyck K, De Meer. Publisher Correction: Trans-ancestry genome-wide association meta-analysis of prostate cancer identifies new susceptibility loci and informs genetic risk prediction. Nat Genet. e-Pub 2021. PMID: 33473200.
- Han Y, Zhang M, Xu J, Li J, Xu Y, Thompson TC, Logothetis CJ, Sun D, Gu J. Genome-wide DNA methylation profiling of leukocytes identifies CpG methylation signatures of aggressive prostate cancer. Am J Cancer Res 11(3):968-978, 2021. e-Pub 2021. PMID: 33791167.
- Brandão A, Paulo P, Maia S, Pinheiro M, Peixoto A, Cardoso M, Silva MP, Santos C, Eeles RA, Kote-Jarai Z, Muir K, Ukgpcs Collaborators , Schleutker J, Wang Y, Pashayan N, Batra J, Apcb BioResource , Grönberg H, Neal DE, Nordestgaard BG, Tangen CM, Southey MC, Wolk A, Albanes D, Haiman CA, Travis RC, Stanford JL, Mucci LA, West CML, Nielsen SF, Kibel AS, Cussenot O, Berndt SI, Koutros S, Sørensen KD, Cybulski C, Grindedal EM, Park JY, Ingles SA, Maier C, Hamilton RJ, Rosenstein BS, Vega A, The Impact Study Steering Committee And Collaborators , Kogevinas M, Wiklund F, Penney KL, Brenner H, John EM, Kaneva R, Logothetis CJ, Neuhausen SL, Ruyck K, Razack A, Newcomb LF, Canary Pass Investigators , Lessel D, Usmani N, Claessens F, Gago-Dominguez M, Townsend PA, Roobol MJ, The Profile Study Steering Committee , The Practical Consortium , Teixeira MR. The CHEK2 Variant C.349A>G Is Associated with Prostate Cancer Risk and Carriers Share a Common Ancestor. Cancers (Basel) 12(11), 2020. e-Pub 2020. PMID: 33158149.
- Palanisamy N, Yang J, Shepherd PDA, Li-Ning-Tapia EM, Labanca E, Manyam GC, Ravoori MK, Kundra V, Araujo JC, Efstathiou E, Pisters LL, Wan X, Wang X, Vazquez ES, Aparicio AM, Carskadon SL, Tomlins SA, Kunju LP, Chinnaiyan AM, Broom BM, Logothetis CJ, Troncoso P, Navone NM. The MD Anderson Prostate Cancer Patient-derived Xenograft Series (MDA PCa PDX) Captures the Molecular Landscape of Prostate Cancer and Facilitates Marker-driven Therapy Development. Clin Cancer Res 26(18):4933-4946, 2020. e-Pub 2020. PMID: 32576626.
- Deng Y, Xie K, Logothetis CJ, Thompson TC, Kim J, Huang M, Chang DW, Gu J, Wu X, Ye Y. Genetic Variants in Epithelial Mesenchymal Transition Genes as Predictors of Clinical Outcomes in Localized Prostate Cancer. Carcinogenesis 41(8):1057-1064, 2020. e-Pub 2020. PMID: 32215555.
- Malihi PD, Graf RP, Rodriguez A, Ramesh N, Lee J, Sutton R, Jiles R, Ruiz Velasco C, Sei E, Kolatkar A, Logothetis C, Navin NE, Corn P, Aparicio AM, Dittamore R, Hicks J, Kuhn P, Zurita AJ. Single-cell circulating tumor cell analysis reveals genomic instability as a distinctive feature of aggressive prostate cancer. Clin Cancer Res 26(15):4143-4153, 2020. e-Pub 2020. PMID: 32341031.
- Fizazi K, Drake CG, Beer TM, Kwon ED, Scher HI, Gerritsen WR, Bossi A, den Eertwegh AJMV, Krainer M, Houede N, Santos R, Mahammedi H, Ng S, Danielli R, Franke FA, Sundar S, Agarwal N, Bergman AM, Ciuleanu TE, Korbenfeld E, Sengeløv L, Hansen S, McHenry MB, Chen A, Logothetis C, CA184-043, Investigators. Final Analysis of the Ipilimumab Versus Placebo Following Radiotherapy Phase III Trial in Postdocetaxel Metastatic Castration-resistant Prostate Cancer Identifies an Excess of Long-term Survivors. Eur Urol. e-Pub 2020. PMID: 32811715.
- Halabi S, Dutta S, Tangen CM, Rosenthal M, Petrylak DP, Thompson IM, Chi KN, De Bono JS, Araujo JC, Logothetis C, Eisenberger MA, Quinn DI, Fizazi K, Morris MJ, Higano CS, Tannock IF, Small EJ, Kelly WK. Clinical outcomes in men of diverse ethnic backgrounds with metastatic castration-resistant prostate cancer. Ann Oncol 31(7):930-941, 2020. e-Pub 2020. PMID: 32289380.
- Labanca E, Vazquez ES, Corn PG, Roberts JM, Wang F, Logothetis CJ, Navone NM. Fibroblast growth factors signaling in bone metastasis. Endocr Relat Cancer 27(7):R255-R265, 2020. PMID: 32369771.
- Ramesh N, Sei E, Tsai PC, Bai S, Zhao Y, Troncoso P, Corn PG, Logothetis C, Zurita AJ, Navin NE. Decoding the evolutionary response to prostate cancer therapy by plasma genome sequencing. Genome Biol 21(1):162, 2020. e-Pub 2020. PMID: 32631448.
- Xu J, Chang WS, Tsai CW, Bau DT, Davis JW, Thompson TC, Logothetis CJ, Gu J. Mitochondrial DNA copy number in peripheral blood leukocytes is associated with biochemical recurrence in prostate cancer patients in African Americans. Carcinogenesis 41(3):267-273, 2020. e-Pub 2019. PMID: 31408512.
- Yang G, Bondaruk J, Cogdell D, Wang Z, Lee S, Lee JG, Zhang S, Choi W, Wang Y, Liang Y, Wang G, Wang Y, Yao H, Dadhania V, Gao J, Logothetis C, Siefker-Radtke A, Kamat A, Dinney C, Theodorescu D, Kimmel M, Wei P, Guo CC, Weinstein JN, McConkey DJ, Czerniak B. Urothelial-to-Neural Plasticity Drives Progression to Small Cell Bladder Cancer. Science 23(6):101201. e-Pub 2020. PMID: 32521509.
- Gregg JR, Davis JW, Reichard C, Wang X, Achim M, Chapin BF, Pisters L, Pettaway C, Ward JF, Choi S, Nguyen QN, Kuban D, Babaian R, Troncoso P, Madsen LT, Logothetis C, Kim J. Determining Clinically Based Factors Associated With Reclassification in the Pre-MRI Era using a Large Prospective Active Surveillance Cohort. Urology 138:91-97, 2020. e-Pub 2019. PMID: 31899230.
- Gillessen S, Attard G, Beer TM, Beltran H, Bjartell A, Bossi A, Briganti A, Bristow RG, Chi KN, Clarke N, Davis ID, de Bono J, Drake CG, Duran I, Eeles R, Efstathiou E, Evans CP, Fanti S, Feng FY, Fizazi K, Frydenberg M, Gleave M, Halabi S, Heidenreich A, Heinrich D, Higano CTS, Hofman MS, Hussain M, James N, Kanesvaran R, Kantoff P, Khauli RB, Leibowitz R, Logothetis C, Maluf F, Millman R, Morgans AK, Morris MJ, Mottet N, Mrabti H, Murphy DG, Murthy V, Oh WK, Ost P, O'Sullivan JM, Padhani AR, Parker C, Poon DMC, Pritchard CC, Reiter RE, Roach M, Rubin M, Ryan CJ, Saad F, Sade JP, Sartor O, Scher HI, Shore N, Small E, Smith M, Soule H, Sternberg CN, Steuber T, Suzuki H, Sweeney C, Sydes MR, Taplin ME, Tombal B, Türkeri L, van Oort I, Zapatero A, Omlin A. Management of Patients with Advanced Prostate Cancer: Report of the Advanced Prostate Cancer Consensus Conference 2019. Eur Urol 77(4):508-547, 2020. e-Pub 2020. PMID: 32001144.
- Subudhi SK, Vence L, Zhao H, Blando J, Yadav SS, Xiong Q, Reuben A, Aparicio A, Corn PG, Chapin BF, Pisters LL, Troncoso P, Tidwell RS, Thall P, Wu CJ, Zhang J, Logothetis CL, Futreal A, Allison JP, Sharma P. Neoantigen responses, immune correlates, and favorable outcomes after ipilimumab treatment of patients with prostate cancer. Sci Transl Med 12(537), 2020. PMID: 32238575.
- Halabi S, Dutta S, Tangen CM, Rosenthal M, Petrylak DP, Thompson IM, Chi KN, De Bono JS, Araujo JC, Logothetis C, Eisenberger MA, Quinn DI, Fizazi K, Morris MJ, Higano CS, Tannock IF, Small EJ, Kelly WK. Comparative Survival of Asian and White Metastatic Castration-Resistant Prostate Cancer Men Treated With Docetaxel. JNCI Cancer Spectr 4(2):pkaa003, 2020. e-Pub 2020. PMID: 32368717.
- Corn PG, Zhang M, Nogueras-Gonzalez GM, Xiao L, Zurita AJ, Subudhi SK, Tu SM, Aparicio AM, Coarfa C, Rajapakshe K, Huang S, Navone NM, Lin SH, Wang G, Ramachandran S, Titus MA, Panaretakis T, Gallick GE, Efstathiou E, Troncoso P, Logothetis C. A Phase II Study of Cabozantinib and Androgen Ablation in Patients with Hormone-Naïve Metastatic Prostate Cancer. Clin Cancer Res 26(5):990-999, 2020. e-Pub 2020. PMID: 31941830.
- Boukovala M, Spetsieris N, Weldon JA, Tsikkinis A, Hoang A, Aparicio A, Tu SM, Araujo JC, Zurita AJ, Corn PG, Pagliaro L, Kim J, Wang J, Subudhi SK, Tannir NM, Logothetis CJ, Troncoso P, Wen S, Efstathiou E. A candidate androgen signalling signature predictive of response to abiraterone acetate in men with metastatic castration-resistant prostate cancer. Eur J Cancer 127:67-75, 2020. e-Pub 2020. PMID: 31986451.
- Efstathiou E, Titus M, Wen S, Troncoso P, Hoang A, Corn P, Prokhorova I, Araujo J, Dmuchowski C, Melhem-Bertrandt A, Patil S, Logothetis CJ. Enzalutamide in Combination with Abiraterone Acetate in Bone Metastatic Castration-resistant Prostate Cancer Patients. Eur Urol Oncol 3(1):119-127, 2020. e-Pub 2019. PMID: 31412017.
- Tang C, Hoffman KE, Allen PK, Gabel M, Schreiber D, Choi S, Chapin BF, Nguyen QN, Davis JW, Corn P, Logothetis C, Ward J, Frank SJ, Navai N, McGuire SE, Anscher M, Pisters L, Pettaway CA, Kumar R, Linson P, Tripuraneni P, Tomaszewski JJ, Patel AB, Augspurger M, Kuban DA. Contemporary prostate cancer treatment choices in multidisciplinary clinics referenced to national trends. Cancer 126(3):506-514, 2020. e-Pub 2019. PMID: 31742674.
- Xu J, Chang WS, Tsai CW, Bau DT, Xu Y, Davis JW, Thompson TC, Logothetis CJ, Gu J. Leukocyte telomere length is associated with aggressive prostate cancer in localized prostate cancer patients. EBioMedicine 52:102616, 2020. e-Pub 2020. PMID: 31981976.
- Tzelepi V, Logotheti S, Efstathiou E, Troncoso P, Aparicio A, Sakellakis M, Hoang A, Perimenis P, Melachrinou M, Logothetis C, Zolota V. Epigenetics and prostate cancer: defining the timing of DNA methyltransferase deregulation during prostate cancer progression. Pathology 52(2):218-227, 2020. e-Pub 2019. PMID: 31864524.
- Koinis F, Corn P, Parikh N, Song J, Vardaki I, Mourkioti I, Lin SH, Logothetis C, Panaretakis T, Gallick G. Resistance to MET/VEGFR2 Inhibition by Cabozantinib Is Mediated by YAP/TBX5-Dependent Induction of FGFR1 in Castration-Resistant Prostate Cancer. Cancers (Basel) 12(1), 2020. e-Pub 2020. PMID: 31963871.
- Gillessen S, Omlin A, Attard G, de Bono JS, Efstathiou E, Fizazi K, Halabi S, Nelson PS, Sartor O, Smith MR, Soule HR, Akaza H, Beer TM, Beltran H, Chinnaiyan AM, Daugaard G, Davis ID, De Santis M, Drake CG, Eeles RA, Fanti S, Gleave ME, Heidenreich A, Hussain M, James ND, Lecouvet FE, Logothetis CJ, Mastris K, Nilsson S, Oh WK, Olmos D, Padhani AR, Parker C, Rubin MA, Schalken JA, Scher HI, Sella A, Shore ND, Small EJ, Sternberg CN, Suzuki H, Sweeney CJ, Tannock IF, Tombal B. Management of patients with advanced prostate cancer: recommendations of the St Gallen Advanced Prostate Cancer Consensus Conference (APCCC) 2015. Ann Oncol 30(12):e3, 2019. PMID: 32041688.
- Dondossola E, Casarin S, Paindelli C, De-Juan-Pardo EM, Hutmacher DW, Logothetis CJ, Friedl P. Radium 223-Mediated Zonal Cytotoxicity of Prostate Cancer in Bone. J Natl Cancer Inst 111(10):1042-1050, 2019. PMID: 30657953.
- Efstathiou E, Davis JW, Pisters L, Li W, Wen S, McMullin RP, Gormley M, Ricci D, Titus M, Hoang A, Zurita AJ, Tran N, Peng W, Kheoh T, Molina A, Troncoso P, Logothetis CJ. Clinical and Biological Characterisation of Localised High-risk Prostate Cancer: Results of a Randomised Preoperative Study of a Luteinising Hormone-releasing Hormone Agonist with or Without Abiraterone Acetate plus Prednisone. Eur Urol 76(4):418-424, 2019. e-Pub 2019. PMID: 31176622.
- Corn PG, Heath EI, Zurita A, Ramesh N, Xiao L, Sei E, Li-Ning-Tapia E, Tu SM, Subudhi SK, Wang J, Wang X, Efstathiou E, Thompson TC, Troncoso P, Navin N, Logothetis CJ, Aparicio AM. Cabazitaxel plus carboplatin for the treatment of men with metastatic castration-resistant prostate cancers: a randomised, open-label, phase 1-2 trial. Lancet Oncol 20(10):1432-1443, 2019. e-Pub 2019. PMID: 31515154.
- Aparicio A, Thall P, Logothetis C. Radiotherapy for metastatic prostate cancer. Lancet 394(10201):829-830, 2019. PMID: 31498098.
- Sinha KM, Bagheri-Yarmand R, Lahiri S, Lu Y, Zhang M, Amra S, Rizvi Y, Wan X, Navone N, Ozpolat B, Logothetis C, Gagel RF, Huard J. Oncogenic and osteolytic functions of histone demethylase NO66 in castration-resistant prostate cancer. Oncogene 38(25):5038-5049, 2019. e-Pub 2019. PMID: 30858546.
- van der Kwast TH, Helleman J, Nieboer D, Bruinsma SM, Roobol MJ, Movember Foundation's Global Action Plan Prostate Cancer Active Surveillance (GAP3) Consortium, Trock B, Ehdaie B, Carroll P, Filson C, Kim J, Logothetis C, Morgan T, Klotz L, Pickles T, Hyndman E, Moore CM, Gnanapragasam V, Van Hemelrijck M, Dasgupta P, Bangma C, Roobol M, Villers A, Rannikko A, Valdagni R, Perry A, Hugosson J, Rubio-Briones J, Bjartell A, Hefermehl L, Shiong LL, Frydenberg M, Kakehi Y, Chung BH, van der Kwast T, Obbink H, van der Linden W, Hulsen T, de Jonge C, Kattan M, Xinge J, Muir K, Lophatananon A, Fahey M, Steyerberg E, Nieboer D, Zhang L, Guo W, Benfante N, Cowan J, Patil D, Tolosa E, Kim TK, Mamedov A, LaPointe V, Crump T, Kimberly-Duffell J, Santaolalla A, Nieboer D, Olivier JT, Rancati T, Ahlgren H, Mascarós J, Löfgren A, Lehmann K, Lin CH, Hirama H, Lee KS, Jenster G, Auvinen A, Bjartell A, Haider M, van Bochove K, Carter B, Gledhill S, Buzza M, Bangma C, Roobol M, Bruinsma S, Helleman J. Consistent Biopsy Quality and Gleason Grading Within the Global Active Surveillance Global Action Plan 3 Initiative: A Prerequisite for Future Studies. Eur Urol Oncol 2(3):333-336, 2019. e-Pub 2018. PMID: 31200849.
- Dutta P, Salzillo TC, Pudakalakatti S, Gammon ST, Kaipparettu BA, McAllister F, Wagner S, Frigo DE, Logothetis CJ, Zacharias NM, Bhattacharya PK. Assessing Therapeutic Efficacy in Real-time by Hyperpolarized Magnetic Resonance Metabolic Imaging. Cells 8(4), 2019. e-Pub 2019. PMID: 30978984.
- Paindelli C, Navone N, Logothetis CJ, Friedl P, Dondossola E. Engineered bone for probing organotypic growth and therapy response of prostate cancer tumoroids in vitro. Biomaterials 197:296-304, 2019. e-Pub 2019. PMID: 30682644.
- Zacharias N, Lee J, Ramachandran S, Shanmugavelandy S, McHenry J, Dutta P, Millward S, Gammon S, Efstathiou E, Troncoso P, Frigo DE, Piwnica-Worms D, Logothetis CJ, Maity SN, Titus MA, Bhattacharya P. Androgen Receptor Signaling in Castration-Resistant Prostate Cancer Alters Hyperpolarized Pyruvate to Lactate Conversion and Lactate Levels In Vivo. Mol Imaging Biol 21(1):86-94, 2019. e-Pub 2018. PMID: 29748904.
- Halabi S, Dutta S, Tangen CM, Rosenthal M, Petrylak DP, Thompson IM, Chi KN, Araujo JC, Logothetis C, Quinn DI, Fizazi K, Morris MJ, Eisenberger MA, George DJ, De Bono JS, Higano CS, Tannock IF, Small EJ, Kelly WK. Overall Survival of Black and White Men With Metastatic Castration-Resistant Prostate Cancer Treated With Docetaxel. J Clin Oncol 37(5):JCO1801279, 2019. e-Pub 2018. PMID: 30576268.
- Schumacher FR, Olama AAA, Berndt SI, Benlloch S, Ahmed M, Saunders EJ, Dadaev T, Leongamornlert D, Anokian E, Cieza-Borrella C, Goh C, Brook MN, Sheng X, Fachal L, Dennis J, Tyrer J, Muir K, Lophatananon A, Stevens VL, Gapstur SM, Carter BD, Tangen CM, Goodman PJ, Thompson IM, Batra J, Chambers S, Moya L, Clements J, Horvath L, Tilley W, Risbridger GP, Gronberg H, Aly M, Nordström T, Pharoah P, Pashayan N, Schleutker J, Tammela TLJ, Sipeky C, Auvinen A, Albanes D, Weinstein S, Wolk A, Håkansson N, West CML, Dunning AM, Burnet N, Mucci LA, Giovannucci E, Andriole GL, Cussenot O, Cancel-Tassin G, Koutros S, Beane Freeman LE, Sorensen KD, Orntoft TF, Borre M, Maehle L, Grindedal EM, Neal DE, Donovan JL, Hamdy FC, Martin RM, Travis RC, Key TJ, Hamilton RJ, Fleshner NE, Finelli A, Ingles SA, Stern MC, Rosenstein BS, Kerns SL, Ostrer H, Lu YJ, Zhang HW, Feng N, Mao X, Guo X, Wang G, Sun Z, Giles GG, Southey MC, MacInnis RJ, FitzGerald LM, Kibel AS, Drake BF, Vega A, Gómez-Caamaño A, Szulkin R, Eklund M, Kogevinas M, Llorca J, Castaño-Vinyals G, Penney KL, Stampfer M, Park JY, Sellers TA, Lin HY, Stanford JL, Cybulski C, Wokolorczyk D, Lubinski J, Ostrander EA, Geybels MS, Nordestgaard BG, Nielsen SF, Weischer M, Bisbjerg R, Røder MA, Iversen P, Brenner H, Cuk K, Holleczek B, Maier C, Luedeke M, Schnoeller T, Kim J, Logothetis CJ, John EM, Teixeira MR, Paulo P, Cardoso M, Neuhausen SL, Steele L, Ding YC, De Ruyck K, De Meerleer G, Ost P, Razack A, Lim J, Teo SH, Lin DW, Newcomb LF, Lessel D, Gamulin M, Kulis T, Kaneva R, Usmani N, Singhal S, Slavov C, Mitev V, Parliament M, Claessens F, Joniau S, Van den Broeck T, Larkin S, Townsend PA, Aukim-Hastie C, Gago-Dominguez M, Castelao JE, Martinez ME, Roobol MJ, Jenster G, van Schaik RHN, Menegaux F, Truong T, Koudou YA, Xu J, Khaw KT, Cannon-Albright L, Pandha H, Michael A, Thibodeau SN, McDonnell SK, Schaid DJ, Lindstrom S, Turman C, Ma J, Hunter DJ, Riboli E, Siddiq A, Canzian F, Kolonel LN, Le Marchand L, Hoover RN, Machiela. Author Correction: Association analyses of more than 140,000 men identify 63 new prostate cancer susceptibility loci. Nat Genet 51(2):363, 2019. e-Pub 2019. PMID: 30622367.
- Majewski T, Yao H, Bondaruk J, Chung W, Lee S, Lee JG, Zhang S, Cogdell D, Yang G, Choi W, Dinney C, Grossman HB, Logothetis C, Scherer SE, Guo CC, Zhang L, Wei P, Weinstein JN, Issa JP, Baggerly K, McConkey DJ, Czerniak B. Whole-Organ Genomic Characterization of Mucosal Field Effects Initiating Bladder Carcinogenesis. Cell Rep 26(8):2241-2256.e4, 2019. PMID: 30784602.
- Tosco L, Briganti A, D'amico AV, Eastham J, Eisenberger M, Gleave M, Haustermans K, Logothetis CJ, Saad F, Sweeney C, Taplin ME, Fizazi K. Systematic Review of Systemic Therapies and Therapeutic Combinations with Local Treatments for High-risk Localized Prostate Cancer. Eur Urol 75(1):44-60, 2019. e-Pub 2018. PMID: 30286948.
- Wang Q, Gregg JR, Gu J, Ye Y, Chang DW, Davis JW, Thompson TC, Kim J, Logothetis CJ, Wu X. Genetic associations of T cell cancer immune response with tumor aggressiveness in localized prostate cancer patients and disease reclassification in an active surveillance cohort. Oncoimmunology 8(1):e1483303, 2019. e-Pub 2018. PMID: 30546938.
- Dondossola E, Alexander S, Holzapfel BM, Filippini S, Starbuck MW, Hoffman RM, Navone N, De-Juan-Pardo EM, Logothetis CJ, Hutmacher DW, Friedl P. Intravital microscopy of osteolytic progression and therapy response of cancer lesions in the bone. Sci Transl Med 10(452), 2018. PMID: 30068572.
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- Logothetis C, Morris MJ, Den R, Coleman RE. Current perspectives on bone metastases in castrate-resistant prostate cancer. Cancer Metastasis Rev 37(1):189-196, 2018. PMID: 29380085.
- Zhang W, Liu B, Wu W, Li L, Broom BM, Basourakos SP, Korentzelos D, Luan Y, Wang J, Yang G, Park S, Azad AK, Cao X, Kim J, Corn PG, Logothetis CJ, Aparicio AM, Chinnaiyan AM, Navone N, Troncoso P, Thompson TC. Targeting the MYCN-PARP-DNA Damage Response Pathway in Neuroendocrine Prostate Cancer. Clin Cancer Res 24(3):696-707, 2018. e-Pub 2017. PMID: 29138344.
- Soundararajan R, Aparicio AM, Logothetis CJ, Mani SA, Maity SN. Function of Tumor Suppressors in Resistance to Antiandrogen Therapy and Luminal Epithelial Plasticity of Aggressive Variant Neuroendocrine Prostate Cancers. Front Oncol 8:69, 2018. e-Pub 2018. PMID: 29600194.
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- Lin SC, Lee YC, Yu G, Cheng CJ, Zhou X, Chu K, Murshed M, Le NT, Baseler L, Abe JI, Fujiwara K, deCrombrugghe B, Logothetis CJ, Gallick GE, Yu-Lee LY, Maity SN, Lin SH. Endothelial-to-Osteoblast Conversion Generates Osteoblastic Metastasis of Prostate Cancer. Dev Cell 41(5):467-480.e3, 2017. PMID: 28586644.
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- Gao J, Ward JF, Pettaway CA, Shi LZ, Subudhi SK, Vence LM, Zhao H, Chen J, Chen H, Efstathiou E, Troncoso P, Allison JP, Logothetis CJ, Wistuba II, Sepulveda MA, Sun J, Wargo J, Blando J, Sharma P. VISTA is an inhibitory immune checkpoint that is increased after ipilimumab therapy in patients with prostate cancer. Nat Med 23(5):551-555, 2017. e-Pub 2017. PMID: 28346412.
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- Aparicio A, Logothetis CJ. Reply to J.B. Aragon-Ching and D. Dalela et al. J Clin Oncol 35(8):917-918, 2017. e-Pub 2016. PMID: 27937088.
- Tu H, Gu J, Meng QH, Kim J, Strom S, Davis JW, He Y, Wagar EA, Thompson TC, Logothetis CJ, Wu X. Low serum testosterone is associated with tumor aggressiveness and poor prognosis in prostate cancer. Oncol Lett 13(3):1949-1957, 2017. e-Pub 2017. PMID: 28454349.
- Beer TM, Kwon ED, Drake CG, Fizazi K, Logothetis C, Gravis G, Ganju V, Polikoff J, Saad F, Humanski P, Piulats JM, Gonzalez Mella P, Ng SS, Jaeger D, Parnis FX, Franke FA, Puente J, Carvajal R, Sengeløv L, McHenry MB, Varma A, van den Eertwegh AJ, Gerritsen W. Randomized, Double-Blind, Phase III Trial of Ipilimumab Versus Placebo in Asymptomatic or Minimally Symptomatic Patients With Metastatic Chemotherapy-Naive Castration-Resistant Prostate Cancer. J Clin Oncol 35(1):40-47, 2017. e-Pub 2016. PMID: 28034081.
- Bilen MA, Hess KR, Campbell MT, Wang J, Broaddus RR, Karam JA, Ward JF, Wood CG, Choi SL, Rao P, Zhang M, Naing A, General R, Cauley DH, Lin SH, Logothetis CJ, Pisters LL, Tu SM. Intratumoral heterogeneity and chemoresistance in nonseminomatous germ cell tumor of the testis. Oncotarget 7(52):86280-86289, 2016. e-Pub 2016. PMID: 27861143.
- Shu X, Ye Y, Gu J, He Y, Davis JW, Thompson TC, Logothetis CJ, Kim J, Wu X. Genetic variants of the Wnt signaling pathway as predictors of aggressive disease and reclassification in men with early stage prostate cancer on active surveillance. Carcinogenesis 37(10):965-71, 2016. e-Pub 2016. PMID: 27515962.
- Kuhn P, Carlsson A, Luttgen MS, Dizon KK, Troncoso P, Corn P, Kolatkar A, Hicks JB, Logothetis C, Zurita AJ. Paired high-content analysis of prostate cancer cells in bone marrow and blood characterizes increased androgen receptor expression in tumor cell clusters. Clin Cancer Res. e-Pub 2016. PMID: 27702818.
- Maity SN, Titus MA, Gyftaki R, Wu G, Lu JF, Ramachandran S, Li-Ning-Tapia EM, Logothetis CJ, Araujo JC, Efstathiou E. Targeting of CYP17A1 Lyase by VT-464 Inhibits Adrenal and Intratumoral Androgen Biosynthesis and Tumor Growth of Castration Resistant Prostate Cancer. Sci Rep 6:35354, 2016. e-Pub 2016. PMID: 27748439.
- Subudhi SK, Aparicio A, Gao J, Zurita AJ, Araujo JC, Logothetis CJ, Tahir SA, Korivi BR, Slack RS, Vence L, Emerson RO, Yusko E, Vignali M, Robins HS, Sun J, Allison JP, Sharma P. Clonal expansion of CD8 T cells in the systemic circulation precedes development of ipilimumab-induced toxicities. Proc Natl Acad Sci U S A 113(42):11919-11924, 2016. e-Pub 2016. PMID: 27698113.
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- Davis JW, Ward JF, Pettaway CA, Wang X, Kuban D, Frank SJ, Lee AK, Pisters LL, Matin SF, Shah JB, Karam JA, Chapin BF, Papadopoulos JN, Achim M, Hoffman KE, Pugh TJ, Choi S, Troncoso P, Logothetis CJ, Kim J. Disease reclassification risk with stringent criteria and frequent monitoring in men with favourable-risk prostate cancer undergoing active surveillance. BJU Int 118(1):68-76, 2016. e-Pub 2015. PMID: 26059275.
- Tu SM, Bilen MA, Hess KR, Broaddus RR, Kopetz S, Wei C, Pagliaro LC, Karam JA, Ward JF, Wood CG, Rao P, Tu ZH, General R, Chen AH, Nieto YL, Yeung SC, Lin SH, Logothetis CJ, Pisters LL. Intratumoral heterogeneity: Role of differentiation in a potentially lethal phenotype of testicular cancer. Cancer 122(12):1836-43, 2016. e-Pub 2016. PMID: 27018785.
- Halabi S, Kelly WK, Ma H, Zhou H, Solomon NC, Fizazi K, Tangen CM, Rosenthal M, Petrylak DP, Hussain M, Vogelzang NJ, Thompson IM, Chi KN, de Bono J, Armstrong AJ, Eisenberger MA, Fandi A, Li S, Araujo JC, Logothetis CJ, Quinn DI, Morris MJ, Higano CS, Tannock IF, Small EJ. Meta-Analysis Evaluating the Impact of Site of Metastasis on Overall Survival in Men With Castration-Resistant Prostate Cancer. J Clin Oncol 34(14):1652-9, 2016. e-Pub 2016. PMID: 26951312.
- Kim J, Davis JW, Klein EA, Magi-Galluzzi C, Lotan Y, Ward JF, Pisters LL, Basler JW, Pettaway CA, Stephenson A, Li Ning Tapia EM, Efstathiou E, Wang X, Do KA, Lee JJ, Gorlov IP, Vornik LA, Hoque AM, Prokhorova IN, Parnes HL, Lippman SM, Thompson IM, Brown PH, Logothetis CJ, Troncoso P. Tissue Effects in a Randomized Controlled Trial of Short-term Finasteride in Early Prostate Cancer. EBioMedicine 7:85-93, 2016. e-Pub 2016. PMID: 27322462.
- Scher HI, Morris MJ, Stadler WM, Higano C, Basch E, Fizazi K, Antonarakis ES, Beer TM, Carducci MA, Chi KN, Corn PG, de Bono JS, Dreicer R, George DJ, Heath EI, Hussain M, Kelly WK, Liu G, Logothetis C, Nanus D, Stein MN, Rathkopf DE, Slovin SF, Ryan CJ, Sartor O, Small EJ, Smith MR, Sternberg CN, Taplin ME, Wilding G, Nelson PS, Schwartz LH, Halabi S, Kantoff PW, Armstrong AJ. Trial Design and Objectives for Castration-Resistant Prostate Cancer: Updated Recommendations From the Prostate Cancer Clinical Trials Working Group 3. J Clin Oncol 34(12):1402-18, 2016. e-Pub 2016. PMID: 26903579.
- Parker PA, Davis JW, Latini DM, Baum G, Wang X, Ward JF, Kuban D, Frank SJ, Lee AK, Logothetis CJ, Kim J. Relationship between illness uncertainty, anxiety, fear of progression and quality of life in men with favourable-risk prostate cancer undergoing active surveillance. BJU Int 117(3):469-77, 2016. e-Pub 2015. PMID: 25714186.
- Aparicio AM, Shen L, Tapia EL, Lu JF, Chen HC, Zhang J, Wu G, Wang X, Troncoso P, Corn P, Thompson TC, Broom B, Baggerly K, Maity SN, Logothetis CJ. Combined Tumor Suppressor Defects Characterize Clinically Defined Aggressive Variant Prostate Cancers. Clin Cancer Res 22(6):1520-30, 2016. e-Pub 2015. PMID: 26546618.
- Varkaris A, Corn PG, Parikh NU, Efstathiou E, Song JH, Lee YC, Aparicio A, Hoang AG, Gaur S, Thorpe L, Maity SN, Bar Eli M, Czerniak BA, Shao Y, Alauddin M, Lin SH, Logothetis CJ, Gallick GE. Integrating Murine and Clinical Trials with Cabozantinib to Understand Roles of MET and VEGFR2 as Targets for Growth Inhibition of Prostate Cancer. Clin Cancer Res 22(1):107-21, 2016. e-Pub 2015. PMID: 26272062.
- Wang G, Lu X, Dey P, Deng P, Wu CC, Jiang S, Fang Z, Zhao K, Konaparthi R, Hua S, Zhang J, Li-Ning-Tapia EM, Kapoor A, Wu CJ, Patel NB, Guo Z, Ramamoorthy V, Tieu TN, Heffernan T, Zhao D, Shang X, Khadka S, Hou P, Hu B, Jin EJ, Yao W, Pan X, Ding Z, Shi Y, Li L, Chang Q, Troncoso P, Logothetis CJ, McArthur MJ, Chin L, Wang YA, DePinho RA. Targeting YAP-Dependent MDSC Infiltration Impairs Tumor Progression. Cancer Discov 6(1):80-95, 2016. e-Pub 2015. PMID: 26701088.
- Qiao Y, Feng FY, Wang Y, Cao X, Han S, Wilder-Romans K, Navone NM, Logothetis C, Taichman RS, Keller ET, Palapattu GS, Alva AS, Smith DC, Tomlins SA, Chinnaiyan AM, Morgan TM. Mechanistic Support for Combined MET and AR Blockade in Castration-Resistant Prostate Cancer. Neoplasia 18(1):1-9, 2016. PMID: 26806347.
- Zhang T, Tseng C, Zhang Y, Sirin O, Corn PG, Li-Ning-Tapia EM, Troncoso P, Davis J, Pettaway C, Ward J, Frazier ML, Logothetis C, Kolonin MG. CXCL1 mediates obesity-associated adipose stromal cell trafficking and function in the tumour microenvironment. Nat Commun 7:11674, 2016. e-Pub 2016. PMID: 27241286.
- Dayyani F, Zurita AJ, Nogueras-González GM, Slack R, Millikan RE, Araujo JC, Gallick GE, Logothetis CJ, Corn PG. The combination of serum insulin, osteopontin, and hepatocyte growth factor predicts time to castration-resistant progression in androgen dependent metastatic prostate cancer- an exploratory study. BMC Cancer 16:721, 2016. e-Pub 2016. PMID: 27599544.
- Tu H, Gu J, Meng QH, Kim J, Davis JW, He Y, Wagar EA, Thompson TC, Logothetis CJ, Wu X. Mitochondrial DNA copy number in peripheral blood leukocytes and the aggressiveness of localized prostate cancer. Oncotarget 6(39):41988-96, 2015. PMID: 26515605.
- Lee YC, Lin SC, Yu G, Cheng CJ, Liu B, Liu HC, Hawke DH, Parikh NU, Varkaris A, Corn P, Logothetis C, Satcher RL, Yu-Lee LY, Gallick GE, Lin SH. Identification of Bone-Derived Factors Conferring De Novo Therapeutic Resistance in Metastatic Prostate Cancer. Cancer Res 75(22):4949-59, 2015. e-Pub 2015. PMID: 26530902.
- Gartrell BA, Coleman R, Efstathiou E, Fizazi K, Logothetis CJ, Smith MR, Sonpavde G, Sartor O, Saad F. Metastatic Prostate Cancer and the Bone: Significance and Therapeutic Options. Eur Urol 68(5):850-8, 2015. e-Pub 2015. PMID: 26153564.
- Saad F, Shore N, Van Poppel H, Rathkopf DE, Smith MR, de Bono JS, Logothetis CJ, de Souza P, Fizazi K, Mulders PF, Mainwaring P, Hainsworth JD, Beer TM, North S, Fradet Y, Griffin TA, De Porre P, Londhe A, Kheoh T, Small EJ, Scher HI, Molina A, Ryan CJ. Impact of bone-targeted therapies in chemotherapy-naïve metastatic castration-resistant prostate cancer patients treated with abiraterone acetate: post hoc analysis of study COU-AA-302. Eur Urol 68(4):570-7, 2015. e-Pub 2015. PMID: 25985882.
- Zurita AJ, Pisters LL, Wang X, Troncoso P, Dieringer P, Ward JF, Davis JW, Pettaway CA, Logothetis CJ, Pagliaro LC. Integrating chemohormonal therapy and surgery in known or suspected lymph node metastatic prostate cancer. Prostate Cancer Prostatic Dis 18(3):276-80, 2015. e-Pub 2015. PMID: 26171883.
- Salameh A, Lee AK, Cardó-Vila M, Nunes DN, Efstathiou E, Staquicini FI, Dobroff AS, Marchiò S, Navone NM, Hosoya H, Lauer RC, Wen S, Salmeron CC, Hoang A, Newsham I, Lima LA, Carraro DM, Oliviero S, Kolonin MG, Sidman RL, Do KA, Troncoso P, Logothetis CJ, Brentani RR, Calin GA, Cavenee WK, Dias-Neto E, Pasqualini R, Arap W. PRUNE2 is a human prostate cancer suppressor regulated by the intronic long noncoding RNA PCA3. Proc Natl Acad Sci U S A 112(27):8403-8, 2015. e-Pub 2015. PMID: 26080435.
- Pasqualini R, Millikan RE, Christianson DR, Cardó-Vila M, Driessen WH, Giordano RJ, Hajitou A, Hoang AG, Wen S, Barnhart KF, Baze WB, Marcott VD, Hawke DH, Do KA, Navone NM, Efstathiou E, Troncoso P, Lobb RR, Logothetis CJ, Arap W. Targeting the interleukin-11 receptor α in metastatic prostate cancer: A first-in-man study. Cancer 121(14):2411-21, 2015. e-Pub 2015. PMID: 25832466.
- Morris MJ, Molina A, Small EJ, de Bono JS, Logothetis CJ, Fizazi K, de Souza P, Kantoff PW, Higano CS, Li J, Kheoh T, Larson SM, Matheny SL, Naini V, Burzykowski T, Griffin TW, Scher HI, Ryan CJ. Radiographic Progression-Free Survival As a Response Biomarker in Metastatic Castration-Resistant Prostate Cancer: COU-AA-302 Results. J Clin Oncol 33(12):1356-63, 2015. e-Pub 2015. PMID: 25624432.
- Attard G, de Bono JS, Logothetis CJ, Fizazi K, Mukherjee SD, Joshua AM, Schrijvers D, van den Eertwegh AJ, Li W, Molina A, Griffin TW, Kheoh T, Ricci DS, Zelinsky K, Rathkopf DE, Scher HI, Ryan CJ. Improvements in Radiographic Progression-Free Survival Stratified by ERG Gene Status in Metastatic Castration-Resistant Prostate Cancer Patients Treated with Abiraterone Acetate. Clin Cancer Res 21(7):1621-7, 2015. e-Pub 2015. PMID: 25593303.
- Lee YC, Gajdosik MS, Josic D, Clifton JG, Logothetis C, Yu-Lee LY, Gallick GE, Maity SN, Lin SH. Secretome analysis of an osteogenic prostate tumor identifies complex signaling networks mediating cross-talk of cancer and stromal cells within the tumor microenvironment. Mol Cell Proteomics 14(3):471-83, 2015. e-Pub 2014. PMID: 25527621.
- Mandelin J, Cardó-Vila M, Driessen WH, Mathew P, Navone NM, Lin SH, Logothetis CJ, Rietz AC, Dobroff AS, Proneth B, Sidman RL, Pasqualini R, Arap W. Selection and identification of ligand peptides targeting a model of castrate-resistant osteogenic prostate cancer and their receptors. Proc Natl Acad Sci U S A 112(12):3776-81, 2015. e-Pub 2015. PMID: 25762070.
- Ryan CJ, Smith MR, Fizazi K, Saad F, Mulders PF, Sternberg CN, Miller K, Logothetis CJ, Shore ND, Small EJ, Carles J, Flaig TW, Taplin ME, Higano CS, de Souza P, de Bono JS, Griffin TW, De Porre P, Yu MK, Park YC, Li J, Kheoh T, Naini V, Molina A, Rathkopf DE, COU-AA-302 Investigators. Abiraterone acetate plus prednisone versus placebo plus prednisone in chemotherapy-naive men with metastatic castration-resistant prostate cancer (COU-AA-302): final overall survival analysis of a randomised, double-blind, placebo-controlled phase 3 study. Lancet Oncol 16(2):152-60, 2015. e-Pub 2015. PMID: 25601341.
- Mintz PJ, Rietz AC, Cardó-Vila M, Ozawa MG, Dondossola E, Do KA, Kim J, Troncoso P, Logothetis CJ, Sidman RL, Pasqualini R, Arap W. Discovery and horizontal follow-up of an autoantibody signature in human prostate cancer. Proc Natl Acad Sci U S A 112(8):2515-20, 2015. e-Pub 2015. PMID: 25675522.
- Efstathiou E, Titus M, Wen S, Hoang A, Karlou M, Ashe R, Tu SM, Aparicio A, Troncoso P, Mohler J, Logothetis CJ. Molecular Characterization of Enzalutamide-treated Bone Metastatic Castration-resistant Prostate Cancer. Eur Urol 67(1):53-60, 2015. e-Pub 2014. PMID: 24882673.
- Bilen MA, Johnson MM, Mathew P, Pagliaro LC, Araujo JC, Aparicio A, Corn PG, Tannir NM, Wong FC, Fisch MJ, Logothetis CJ, Tu SM. Randomized phase 2 study of bone-targeted therapy containing strontium-89 in advanced castrate-sensitive prostate cancer. Cancer 121(1):69-76, 2015. e-Pub 2014. PMID: 25155428.
- Fizazi K, Pagliaro L, Laplanche A, Fléchon A, Mardiak J, Geoffrois L, Kerbrat P, Chevreau C, Delva R, Rolland F, Theodore C, Roubaud G, Gravis G, Eymard JC, Malhaire JP, Linassier C, Habibian M, Martin AL, Journeau F, Reckova M, Logothetis C, Culine S. Personalised chemotherapy based on tumour marker decline in poor prognosis germ-cell tumours (GETUG 13): a phase 3, multicentre, randomised trial. Lancet Oncol 15(13):1442-50, 2014. e-Pub 2014. PMID: 25456363.
- Rathkopf DE, Smith MR, de Bono JS, Logothetis CJ, Shore ND, de Souza P, Fizazi K, Mulders PF, Mainwaring P, Hainsworth JD, Beer TM, North S, Fradet Y, Van Poppel H, Carles J, Flaig TW, Efstathiou E, Yu EY, Higano CS, Taplin ME, Griffin TW, Todd MB, Yu MK, Park YC, Kheoh T, Small EJ, Scher HI, Molina A, Ryan CJ, Saad F. Updated Interim Efficacy Analysis and Long-term Safety of Abiraterone Acetate in Metastatic Castration-resistant Prostate Cancer Patients Without Prior Chemotherapy (COU-AA-302). Eur Urol 66(5):815-25, 2014. e-Pub 2014. PMID: 24647231.
- Taplin ME, Montgomery B, Logothetis CJ, Bubley GJ, Richie JP, Dalkin BL, Sanda MG, Davis JW, Loda M, True LD, Troncoso P, Ye H, Lis RT, Marck BT, Matsumoto AM, Balk SP, Mostaghel EA, Penning TM, Nelson PS, Xie W, Jiang Z, Haqq CM, Tamae D, Tran N, Peng W, Kheoh T, Molina A, Kantoff PW. Intense Androgen-Deprivation Therapy With Abiraterone Acetate Plus Leuprolide Acetate in Patients With Localized High-Risk Prostate Cancer: Results of a Randomized Phase II Neoadjuvant Study. J Clin Oncol 32(33):3705-15, 2014. e-Pub 2014. PMID: 25311217.
- Smith MR, Sweeney CJ, Corn PG, Rathkopf DE, Smith DC, Hussain M, George DJ, Higano CS, Harzstark AL, Sartor AO, Vogelzang NJ, Gordon MS, de Bono JS, Haas NB, Logothetis CJ, Elfiky A, Scheffold C, Laird AD, Schimmoller F, Basch EM, Scher HI. Cabozantinib in Chemotherapy-Pretreated Metastatic Castration-Resistant Prostate Cancer: Results of a Phase II Nonrandomized Expansion Study. J Clin Oncol 32(30):3391-9, 2014. e-Pub 2014. PMID: 25225437.
- He Y, Gu J, Strom S, Logothetis CJ, Kim J, Wu X. The Prostate Cancer Susceptibility Variant rs2735839 Near KLK3 Gene Is Associated with Aggressive Prostate Cancer and Can Stratify Gleason Score 7 Patients. Clin Cancer Res 20(19):5133-9, 2014. PMID: 25274378.
- Bilen MA, Reyes A, Bhowmick D, Maa A, Bast R, Pisters LL, Lin SH, Logothetis CJ, Tu SM. Variant prostate carcinoma and elevated serum CA-125. Can J Urol 21(5):7442-8, 2014. PMID: 25347368.
- Wan X, Corn PG, Yang J, Palanisamy N, Starbuck MW, Efstathiou E, Tapia EM, Zurita AJ, Aparicio A, Ravoori MK, Vazquez ES, Robinson DR, Wu YM, Cao X, Iyer MK, McKeehan W, Kundra V, Wang F, Troncoso P, Chinnaiyan AM, Logothetis CJ, Navone NM. Prostate cancer cell-stromal cell crosstalk via FGFR1 mediates antitumor activity of dovitinib in bone metastases. Sci Transl Med 6(252):252ra122, 2014. PMID: 25186177.
- Madsen LT, Kuban DA, Choi S, Davis JW, Kim J, Lee AK, Domain D, Levy L, Pisters LL, Pettaway CA, Ward JF, Logothetis C, Hoffman KE. Impact of a clinical trial initiative on clinical trial enrollment in a multidisciplinary prostate cancer clinic. J Natl Compr Canc Netw 12(7):993-8, 2014. PMID: 24994920.
- Beltran H, Tomlins S, Aparicio A, Arora V, Rickman D, Ayala G, Huang J, True L, Gleave ME, Soule H, Logothetis C, Rubin MA. Aggressive variants of castration-resistant prostate cancer. Clin Cancer Res 20(11):2846-50, 2014. e-Pub 2014. PMID: 24727321.
- Kwon ED, Drake CG, Scher HI, Fizazi K, Bossi A, van den Eertwegh AJ, Krainer M, Houede N, Santos R, Mahammedi H, Ng S, Maio M, Franke FA, Sundar S, Agarwal N, Bergman AM, Ciuleanu TE, Korbenfeld E, Sengeløv L, Hansen S, Logothetis C, Beer TM, McHenry MB, Gagnier P, Liu D, Gerritsen WR, CA184-043 Investigators. Ipilimumab versus placebo after radiotherapy in patients with metastatic castration-resistant prostate cancer that had progressed after docetaxel chemotherapy (CA184-043): a multicentre, randomised, double-blind, phase 3 trial. Lancet Oncol 15(7):700-12, 2014. e-Pub 2014. PMID: 24831977.
- Prensner JR, Chen W, Iyer MK, Cao Q, Ma T, Han S, Sahu A, Malik R, Wilder-Romans K, Navone N, Logothetis CJ, Araujo JC, Pisters LL, Tewari AK, Canman CE, Knudsen KE, Kitabayashi N, Rubin MA, Demichelis F, Lawrence TS, Chinnaiyan AM, Feng FY. PCAT-1, a long noncoding RNA, regulates BRCA2 and controls homologous recombination in cancer. Cancer Res 74(6):1651-60, 2014. e-Pub 2014. PMID: 24473064.
- Gorlova O, Fedorov A, Logothetis C, Amos C, Gorlov I. Genes with a large intronic burden show greater evolutionary conservation on the protein level. BMC Evol Biol 14(1):50, 2014. e-Pub 2014. PMID: 24629165.
- Gorlov IP, Yang JY, Byun J, Logothetis C, Gorlova OY, Do KA, Amos C. How to get the most from microarray data: advice from reverse genomics. BMC Genomics 15(1):223, 2014. e-Pub 2014. PMID: 24656147.
- Araujo JC, Trudel GC, Saad F, Armstrong AJ, Yu EY, Bellmunt J, Wilding G, McCaffrey J, Serrano SV, Matveev VB, Efstathiou E, Oudard S, Morris MJ, Sizer B, Goebell PJ, Heidenreich A, de Bono JS, Begbie S, Hong JH, Richardet E, Gallardo E, Paliwal P, Durham S, Cheng S, Logothetis CJ. Docetaxel and dasatinib or placebo in men with metastatic castration-resistant prostate cancer (READY): a randomised, double-blind phase 3 trial. Lancet Oncol 14(13):1307-16, 2013. e-Pub 2013. PMID: 24211163.
- Arora VK, Schenkein E, Murali R, Subudhi SK, Wongvipat J, Balbas MD, Shah N, Cai L, Efstathiou E, Logothetis C, Zheng D, Sawyers CL. Glucocorticoid receptor confers resistance to antiandrogens by bypassing androgen receptor blockade. Cell 155(6):1309-22, 2013. PMID: 24315100.
- Harland S, Staffurth J, Molina A, Hao Y, Gagnon DD, Sternberg CN, Cella D, Fizazi K, Logothetis CJ, Kheoh T, Haqq CM, de Bono JS, Scher HI, COU-AA-301 Investigators. Effect of abiraterone acetate treatment on the quality of life of patients with metastatic castration-resistant prostate cancer after failure of docetaxel chemotherapy. Eur J Cancer 49(17):3648-57, 2013. e-Pub 2013. PMID: 23973186.
- Basch E, Autio K, Ryan CJ, Mulders P, Shore N, Kheoh T, Fizazi K, Logothetis CJ, Rathkopf D, Smith MR, Mainwaring PN, Hao Y, Griffin T, Li S, Meyers ML, Molina A, Cleeland C. Abiraterone acetate plus prednisone versus prednisone alone in chemotherapy-naive men with metastatic castration-resistant prostate cancer: patient-reported outcome results of a randomised phase 3 trial. Lancet Oncol 14(12):1193-9, 2013. e-Pub 2013. PMID: 24075621.
- Varkaris A, Gaur S, Parikh NU, Song JH, Dayyani F, Jin JK, Logothetis CJ, Gallick GE. Ligand-independent activation of MET through IGF-1/IGF-1R signaling. Int J Cancer 133(7):1536-46, 2013. e-Pub 2013. PMID: 23526299.
- Autio KA, Bennett AV, Jia X, Fruscione M, Beer TM, George DJ, Carducci MA, Logothetis CJ, Kane RC, Sit L, Rogak L, Morris MJ, Scher HI, Basch EM. Prevalence of pain and analgesic use in men with metastatic prostate cancer using a patient-reported outcome measure. J Oncol Pract 9(5):223-9, 2013. e-Pub 2013. PMID: 23943897.
- Logothetis CJ, Gallick GE, Maity SN, Kim J, Aparicio A, Efstathiou E, Lin SH. Molecular Classification of Prostate Cancer Progression: Foundation for Marker-Driven Treatment of Prostate Cancer. Cancer Discov 3(8):849-61, 2013. e-Pub 2013. PMID: 23811619.
- Chan CH, Morrow JK, Li CF, Gao Y, Jin G, Moten A, Stagg LJ, Ladbury JE, Cai Z, Xu D, Logothetis CJ, Hung MC, Zhang S, Lin HK. Pharmacological Inactivation of Skp2 SCF Ubiquitin Ligase Restricts Cancer Stem Cell Traits and Cancer Progression. Cell 154(3):556-68, 2013. PMID: 23911321.
- Aparicio AM, Harzstark AL, Corn PG, Wen S, Araujo JC, Tu SM, Pagliaro LC, Kim J, Millikan RE, Ryan C, Tannir NM, Zurita AJ, Mathew P, Arap W, Troncoso P, Thall PF, Logothetis CJ. Platinum-Based Chemotherapy for Variant Castrate-Resistant Prostate Cancer. Clin Cancer Res 19(13):3621-30, 2013. e-Pub 2013. PMID: 23649003.
- Dayyani F, Varkaris A, Araujo JC, Song JH, Chatterji T, Trudel GC, Logothetis CJ, Gallick GE. Increased serum insulin-like growth factor-1 levels are associated with prolonged response to dasatinib-based regimens in metastatic prostate cancer. Prostate 73(9):979-85, 2013. e-Pub 2013. PMID: 23371521.
- Lee YC, Jin JK, Cheng CJ, Huang CF, Song JH, Huang M, Brown WS, Zhang S, Yu-Lee LY, Yeh ET, McIntyre BW, Logothetis CJ, Gallick GE, Lin SH. Targeting Constitutively Activated β1 Integrin inhibits Prostate Cancer Metastasis. Mol Cancer Res 11(4):405-17, 2013. e-Pub 2013. PMID: 23339185.
- Smith DC, Smith MR, Sweeney C, Elfiky AA, Logothetis C, Corn PG, Vogelzang NJ, Small EJ, Harzstark AL, Gordon MS, Vaishampayan UN, Haas NB, Spira AI, Lara PN, Lin CC, Srinivas S, Sella A, Schöffski P, Scheffold C, Weitzman AL, Hussain M. Cabozantinib in Patients With Advanced Prostate Cancer: Results of a Phase II Randomized Discontinuation Trial. J Clin Oncol 31(4):412-9, 2013. e-Pub 2012. PMID: 23169517.
- Efstathiou E, Karlou M, Wen S, Hoang A, Pettaway CA, Pisters LL, Maity S, Troncoso P, Logothetis CJ. Integrated Hedgehog signaling is induced following castration in human and murine prostate cancers. Prostate 73(2):153-61, 2013. e-Pub 2012. PMID: 22753310.
- McGuire SE, Lee AK, Cerne JZ, Munsell MF, Levy LB, Kudchadker RJ, Choi SL, Nguyen QN, Hoffman KE, Pugh TJ, Frank SJ, Corn PG, Logothetis CJ, Kuban DA. PSA Response to Neoadjuvant Androgen Deprivation Therapy Is a Strong Independent Predictor of Survival in High-Risk Prostate Cancer in the Dose-Escalated Radiation Therapy Era. Int J Radiat Oncol Biol Phys 85(1):e39-46, 2013. e-Pub 2012. PMID: 23102837.
- Ryan CJ, Smith MR, de Bono JS, Molina A, Logothetis CJ, de Souza P, Fizazi K, Mainwaring P, Piulats JM, Ng S, Carles J, Mulders PF, Basch E, Small EJ, Saad F, Schrijvers D, Van Poppel H, Mukherjee SD, Suttmann H, Gerritsen WR, Flaig TW, George DJ, Yu EY, Efstathiou E, Pantuck A, Winquist E, Higano CS, Taplin ME, Park Y, Kheoh T, Griffin T, Scher HI, Rathkopf DE, COU-AA-302 Investigators. Abiraterone in metastatic prostate cancer without previous chemotherapy. N Engl J Med 368(2):138-48, 2013. e-Pub 2012. PMID: 23228172.
- Zhao H, Logothetis CJ, Gorlov IP, Zeng J, Dai J. Modified logistic regression models using gene coexpression and clinical features to predict prostate cancer progression. Comput Math Methods Med 2013:917502, 2013. e-Pub 2013. PMID: 24367394.
- Logothetis CJ, Basch E, Molina A, Fizazi K, North SA, Chi KN, Jones RJ, Goodman OB, Mainwaring PN, Sternberg CN, Efstathiou E, Gagnon DD, Rothman M, Hao Y, Liu CS, Kheoh TS, Haqq CM, Scher HI, de Bono JS. Effect of abiraterone acetate and prednisone compared with placebo and prednisone on pain control and skeletal-related events in patients with metastatic castration-resistant prostate cancer: exploratory analysis of data from the COU-AA-301 randomised trial. Lancet Oncol 13(12):1210-7, 2012. e-Pub 2012. PMID: 23142059.
- Karlou M, Lu JF, Wu G, Maity S, Tzelepi V, Navone NM, Hoang A, Logothetis CJ, Efstathiou E. Hedgehog signaling inhibition by the small molecule smoothened inhibitor GDC-0449 in the bone forming prostate cancer xenograft MDA PCa 118b. Prostate 72(15):1638-47, 2012. e-Pub 2012. PMID: 22457212.
- Fizazi K, Scher HI, Molina A, Logothetis CJ, Chi KN, Jones RJ, Staffurth JN, North S, Vogelzang NJ, Saad F, Mainwaring P, Harland S, Goodman OB, Sternberg CN, Li JH, Kheoh T, Haqq CM, de Bono JS, for the COU-AA-301 Investigators. Abiraterone acetate for treatment of metastatic castration-resistant prostate cancer: final overall survival analysis of the COU-AA-301 randomised, double-blind, placebo-controlled phase 3 study. Lancet Oncol 13(10):983-992, 2012. e-Pub 2012. PMID: 22995653.
- Som A, Tu SM, Liu J, Wang X, Qiao W, Logothetis C, Corn PG. Response in bone turnover markers during therapy predicts overall survival in patients with metastatic prostate cancer: analysis of three clinical trials. Br J Cancer 107(9):1547-53, 2012. e-Pub 2012. PMID: 23033003.
- Tu SM, Som A, Tu B, Logothetis CJ, Lee MH, Yeung SC. Effect of Paget's disease of bone (osteitis deformans) on the progression of prostate cancer bone metastasis. Br J Cancer 107(4):646-51, 2012. e-Pub 2012. PMID: 22805323.
- Gorlov IP, Byun J, Logothetis CJ. In silico functional profiling of individual prostate cancer tumors: many genes, few functions. Cancer Genomics Proteomics 9(3):109-14, 2012. PMID: 22593245.
- Gorlov IP, Byun J, Zhao H, Logothetis CJ, Gorlova OY. Beyond comparing means: the usefulness of analyzing interindividual variation in gene expression for identifying genes associated with cancer development. J Bioinform Comput Biol 10(2):1241013, 2012. PMID: 22809348.
- Zurita AJ, George DJ, Shore ND, Liu G, Wilding G, Hutson TE, Kozloff M, Mathew P, Harmon CS, Wang SL, Chen I, Chow Maneval E, Logothetis CJ. Sunitinib in combination with docetaxel and prednisone in chemotherapy-naive patients with metastatic, castration-resistant prostate cancer: a phase 1/2 clinical trial. Ann Oncol 23(3):688-94, 2012. e-Pub 2011. PMID: 21821830.
- Zurita AJ, George DJ, Shore ND, Liu G, Wilding G, Hutson TE, Kozloff M, Mathew P, Harmon CS, Wang SL, Chen I, Chow Maneval E, Logothetis CJ. Sunitinib in combination with docetaxel and prednisone in chemotherapy-naive patients with metastatic, castration-resistant prostate cancer: a phase 1/2 clinical trial. Ann Oncol 23(3):688-694, 2012. e-Pub 2019. PMID: 32018662.
- Ye X, Lee YC, Choueiri M, Chu K, Huang CF, Tsai WW, Kobayashi R, Logothetis CJ, Yu-Lee LY, Lin SH. Aberrant expression of katanin p60 in prostate cancer bone metastasis. Prostate 72(3):291-300, 2012. e-Pub 2011. PMID: 21681775.
- Efstathiou E, Titus M, Tsavachidou D, Tzelepi V, Wen S, Hoang A, Molina A, Chieffo N, Smith LA, Karlou M, Troncoso P, Logothetis CJ. Effects of Abiraterone Acetate on Androgen Signaling in Castrate-Resistant Prostate Cancer in Bone. J Clin Oncol 30(6):637-43, 2012. e-Pub 2011. PMID: 22184395.
- Tzelepi V, Zhang J, Lu JF, Kleb B, Wu G, Wan X, Hoang A, Efstathiou E, Sircar K, Navone NM, Troncoso P, Liang S, Logothetis CJ, Maity SN, Aparicio AM. Modeling a Lethal Prostate Cancer Variant with Small-Cell Carcinoma Features. Clin Cancer Res 18(3):666-77, 2012. e-Pub 2011. PMID: 22156612.
- Zurita AJ, Jonasch E, Wang X, Khajavi M, Yan S, Du DZ, Xu L, Herynk MH, McKee KS, Tran HT, Logothetis CJ, Tannir NM, Heymach JV. A cytokine and angiogenic factor (CAF) analysis in plasma for selection of sorafenib therapy in patients with metastatic renal cell carcinoma. Ann Oncol 23(1):46-52, 2012. e-Pub 2011. PMID: 21464158.
- Araujo JC, Mathew P, Armstrong AJ, Braud EL, Posadas E, Lonberg M, Gallick GE, Trudel GC, Paliwal P, Agrawal S, Logothetis CJ. Dasatinib combined with docetaxel for castration-resistant prostate cancer: Results from a phase 1-2 study. Cancer 118(1):63-71, 2012. e-Pub 2011. PMID: 21976132.
- Gorlov IP, Logothetis CJ, Fang S, Gorlova OY, Amos C. Building a statistical model for predicting cancer genes. PLoS One 7(11):e49175, 2012. e-Pub 2012. PMID: 23166609.
- Dayyani F, Parikh NU, Varkaris AS, Song JH, Moorthy S, Chatterji T, Maity SN, Wolfe AR, Carboni JM, Gottardis MM, Logothetis CJ, Gallick GE. Combined Inhibition of IGF-1R/IR and Src Family Kinases Enhances Antitumor Effects in Prostate Cancer by Decreasing Activated Survival Pathways. PLoS One 7(12):e51189, 2012. e-Pub 2012. PMID: 23300537.
- Zurita AJ, Jonasch E, Wang X, Khajavi M, Yan S, Du DZ, Xu L, Herynk MH, McKee KS, Tran HT, Logothetis CJ, Tannir NM, Heymach JV. A cytokine and angiogenic factor (CAF) analysis in plasma for selection of sorafenib therapy in patients with metastatic renal cell carcinoma. Ann Oncol 23(1):46-52, 2012. e-Pub 2019. PMID: 32018383.
- Varkaris A, Corn PG, Gaur S, Dayyani F, Logothetis CJ, Gallick GE. The role of HGF/c-Met signaling in prostate cancer progression and c-Met inhibitors in clinical trials. Expert Opin Investig Drugs 20(12):1677-84, 2011. e-Pub 2011. PMID: 22035268.
- Dayyani F, Gallick GE, Logothetis CJ, Corn PG. Novel Therapies for Metastatic Castrate-Resistant Prostate Cancer. J Natl Cancer Inst 103(22):1665-1675, 2011. e-Pub 2011. PMID: 21917607.
- Staquicini FI, Cardó-Vila M, Kolonin MG, Trepel M, Edwards JK, Nunes DN, Sergeeva A, Efstathiou E, Sun J, Almeida NF, Tu SM, Botz GH, Wallace MJ, O'Connell DJ, Krajewski S, Gershenwald JE, Molldrem JJ, Flamm AL, Koivunen E, Pentz RD, Dias-Neto E, Setubal JC, Cahill DJ, Troncoso P, Do KA, Logothetis CJ, Sidman RL, Pasqualini R, Arap W. Vascular ligand-receptor mapping by direct combinatorial selection in cancer patients. Proc Natl Acad Sci U S A 108(46):18637-18642, 2011. e-Pub 2011. PMID: 22049339.
- Roychowdhury S, Iyer MK, Robinson DR, Lonigro RJ, Wu YM, Cao X, Kalyana-Sundaram S, Sam L, Balbin OA, Quist MJ, Barrette T, Everett J, Siddiqui J, Kunju LP, Navone N, Araujo JC, Troncoso P, Logothetis CJ, Innis JW, Smith DC, Lao CD, Kim SY, Roberts JS, Gruber SB, Pienta KJ, Talpaz M, Chinnaiyan AM. Personalized oncology through integrative high-throughput sequencing: a pilot study. Sci Transl Med 3(111):111ra121, 2011. PMID: 22133722.
- Ryan CJ, Shah S, Efstathiou E, Smith MR, Taplin ME, Bubley GJ, Logothetis CJ, Kheoh T, Kilian C, Haqq CM, Molina A, Small EJ. Phase II Study of Abiraterone Acetate in Chemotherapy-Naive Metastatic Castration-Resistant Prostate Cancer Displaying Bone Flare Discordant with Serologic Response. Clin Cancer Res 17(14):4854-61, 2011. e-Pub 2011. PMID: 21632851.
- Tzelepi V, Efstathiou E, Wen S, Troncoso P, Karlou M, Pettaway CA, Pisters LL, Hoang A, Logothetis CJ, Pagliaro LC. Persistent, Biologically Meaningful Prostate Cancer After 1 Year of Androgen Ablation and Docetaxel Treatment. J Clin Oncol 29(18):2574-81, 2011. e-Pub 2011. PMID: 21606419.
- Aparicio A, Tzelepi V, Araujo JC, Guo CC, Liang S, Troncoso P, Logothetis CJ, Navone NM, Maity SN. Neuroendocrine prostate cancer xenografts with large-cell and small-cell features derived from a single patient's tumor: morphological, immunohistochemical, and gene expression profiles. Prostate 71(8):846-56, 2011. e-Pub 2010. PMID: 21456067.
- Tzelepi V, Karlou M, Wen S, Hoang A, Logothetis C, Troncoso P, Efstathiou E. Expression of hedgehog pathway components in prostate carcinoma microenvironment: shifting the balance towards autocrine signalling. Histopathology 58(7):1037-47, 2011. PMID: 21707705.
- de Bono JS, Logothetis CJ, Molina A, Fizazi K, North S, Chu L, Chi KN, Jones RJ, Goodman OB, Saad F, Staffurth JN, Mainwaring P, Harland S, Flaig TW, Hutson TE, Cheng T, Patterson H, Hainsworth JD, Ryan CJ, Sternberg CN, Ellard SL, Fléchon A, Saleh M, Scholz M, Efstathiou E, Zivi A, Bianchini D, Loriot Y, Chieffo N, Kheoh T, Haqq CM, Scher HI, COU-AA-301 Investigators. Abiraterone and increased survival in metastatic prostate cancer. N Engl J Med 364(21):1995-2005, 2011. PMID: 21612468.
- Fitzpatrick JM, Bellmunt J, Dreicer R, Fleshner NE, Logothetis CJ, Moul JW, Tombal B, Zlotta A. Maximizing outcomes in genitourinary cancers across the treatment continuum. BJU Int 107 Suppl 2:1-12, 2011. PMID: 21382149.
- Bracarda S, Logothetis C, Sternberg CN, Oudard S. Current and emerging treatment modalities for metastatic castration-resistant prostate cancer. BJU Int 107 Suppl 2:13-20, 2011. PMID: 21382150.
- Li J, Ding Z, Wang Z, Lu JF, Maity SN, Navone NM, Logothetis CJ, Mills GB, Kim J. Androgen regulation of 5α-reductase isoenzymes in prostate cancer: implications for prostate cancer prevention. PLoS One 6(12):e28840, 2011. e-Pub 2011. PMID: 22194926.
- Prantl L, Muehlberg F, Navone NM, Song YH, Vykoukal J, Logothetis CJ, Alt EU. Adipose tissue-derived stem cells promote prostate tumor growth. Prostate 70(15):1709-15, 2010. e-Pub 2010. PMID: 20564322.
- Araujo J, Logothetis C. Dasatinib: a potent SRC inhibitor in clinical development for the treatment of solid tumors. Cancer Treat Rev 36(6):492-500, 2010. e-Pub 2010. PMID: 20226597.
- Zhao H, Logothetis CJ, Gorlov IP. Usefulness of the top-scoring pairs of genes for prediction of prostate cancer progression. Prostate Cancer Prostatic Dis 13(3):252-9, 2010. e-Pub 2010. PMID: 20386565.
- Efstathiou E, Abrahams NA, Tibbs RF, Wang X, Pettaway CA, Pisters LL, Mathew PF, Do KA, Logothetis CJ, Troncoso P. Morphologic Characterization of Preoperatively Treated Prostate Cancer: Toward a Post-Therapy Histologic Classification. Eur Urol 57(6):1030-8, 2010. e-Pub 2009. PMID: 19853370.
- Huang CF, Lira C, Chu K, Bilen MA, Lee YC, Ye X, Kim SM, Ortiz A, Wu FL, Logothetis CJ, Yu-Lee LY, Lin SH. Cadherin-11 increases migration and invasion of prostate cancer cells and enhances their interaction with osteoblasts. Cancer Res 70(11):4580-9, 2010. e-Pub 2010. PMID: 20484040.
- Tu SM, Lin SH, Podoloff DA, Logothetis CJ. Multimodality Therapy: Bone-targeted Radioisotope Therapy of Prostate Cancer. Clin Adv Hematol Oncol 8(5):341-51, 2010. PMID: 20551894.
- Carthon BC, Wolchok JD, Yuan J, Kamat A, Ng Tang DS, Sun J, Ku G, Troncoso P, Logothetis CJ, Allison JP, Sharma P. Preoperative CTLA-4 blockade: tolerability and immune monitoring in the setting of a presurgical clinical trial. Clin Cancer Res 16(10):2861-71, 2010. e-Pub 2010. PMID: 20460488.
- Thompson TC, Tahir SA, Li L, Watanabe M, Naruishi K, Yang G, Kadmon D, Logothetis CJ, Troncoso P, Ren C, Goltsov A, Park S. The role of caveolin-1 in prostate cancer: clinical implications. Prostate Cancer Prostatic Dis 13(1):6-11, 2010. e-Pub 2009. PMID: 19581923.
- Efstathiou E, Logothetis CJ. A new therapy paradigm for prostate cancer founded on clinical observations. Clin Cancer Res 16(4):1100-7, 2010. e-Pub 2010. PMID: 20145177.
- Gorlov IP, Sircar K, Zhao H, Maity SN, Navone NM, Gorlova OY, Troncoso P, Pettaway CA, Byun JY, Logothetis CJ. Prioritizing genes associated with prostate cancer development. BMC Cancer 10:599, 2010. e-Pub 2010. PMID: 21044312.
- Byun J, Logothetis CJ, Gorlov IP. Housekeeping genes in prostate tumorigenesis. Int J Cancer 125(11):2603-8, 2009. PMID: 19551858.
- Araujo JC, Poblenz A, Corn P, Parikh NU, Starbuck MW, Thompson JT, Lee F, Logothetis CJ, Darnay BG. Dasatinib inhibits both osteoclast activation and prostate cancer PC-3 cell-induced osteoclast formation. Cancer Biol Ther 8(22):2151-7, 2009. e-Pub 2009. PMID: 19855158.
- Daliani DD, Tannir NM, Papandreou CN, Wang X, Swisher S, Wood CG, Swanson DA, Logothetis CJ, Jonasch E. Prospective assessment of systemic therapy followed by surgical removal of metastases in selected patients with renal cell carcinoma. BJU Int 104(4):456-60, 2009. e-Pub 2009. PMID: 19338544.
- Gorlov IP, Byun J, Gorlova OY, Aparicio AM, Efstathiou E, Logothetis CJ. Candidate pathways and genes for prostate cancer: a meta-analysis of gene expression data. BMC Med Genomics 2:48, 2009. PMID: 19653896.
- Tu SM, Mathew P, Wong FC, Jones D, Johnson MM, Logothetis CJ. Phase I Study of Concurrent Weekly Docetaxel and Repeated Samarium-153 Lexidronam in Patients With Castration-Resistant Metastatic Prostate Cancer. J Clin Oncol 27(20):3319-3324, 2009. e-Pub 2009. PMID: 19414670.
- Gnjatic S, Altorki NK, Tang DN, Tu SM, Kundra V, Ritter G, Old LJ, Logothetis CJ, Sharma P. NY-ESO-1 DNA Vaccine Induces T-Cell Responses That Are Suppressed by Regulatory T Cells. Clin Cancer Res 15(6):2130-9, 2009. e-Pub 2009. PMID: 19276258.
- Tsavachidou D, McDonnell TJ, Wen S, Wang X, Vakar-Lopez F, Pisters LL, Pettaway CA, Wood CG, Do KA, Thall PF, Stephens C, Efstathiou E, Taylor R, Menter DG, Troncoso P, Lippman SM, Logothetis CJ, Kim J. Selenium and vitamin E: cell type- and intervention-specific tissue effects in prostate cancer. J Natl Cancer Inst 101(5):306-20, 2009. e-Pub 2009. PMID: 19244175.
- Pataer A, Swisher SG, Roth JA, Logothetis CJ, Corn P. Inhibition of RNA-dependent protein kinase (PKR) leads to cancer cell death and increases chemosensitivity. Cancer Biol Ther 8(3):245-52, 2009. e-Pub 2009. PMID: 19106640.
- Chen H, Liakou CI, Kamat A, Pettaway C, Ward JF, Tang DN, Sun J, Jungbluth AA, Troncoso P, Logothetis C, Sharma P. Anti-CTLA-4 therapy results in higher CD4+ICOShi T cell frequency and IFN-gamma levels in both nonmalignant and malignant prostate tissues. Proc Natl Acad Sci U S A 106(8):2729-34, 2009. e-Pub 2009. PMID: 19202079.
- Gorlov IP, Gallick GE, Gorlova OY, Amos C, Logothetis CJ. GWAS meets microarray: are the results of genome-wide association studies and gene-expression profiling consistent? Prostate cancer as an example. PLoS One 4(8):e6511, 2009. PMID: 19652704.
- Morris MJ, Basch EM, Wilding G, Hussain M, Carducci MA, Higano C, Kantoff P, Oh WK, Small EJ, George D, Mathew P, Beer TM, Slovin SF, Ryan C, Logothetis C, Scher HI. Department of Defense prostate cancer clinical trials consortium: a new instrument for prostate cancer clinical research. Clin Genitourin Cancer 7(1):51-7, 2009. PMID: 19213669.
- Mathew P, Thall PF, Wen S, Bucana C, Jones D, Horne E, Oh WK, Morris MJ, Lee YC, Logothetis CJ, Lin SH, Fidler IJ. Dynamic change in phosphorylated platelet-derived growth factor receptor in peripheral blood leukocytes following docetaxel therapy predicts progression-free and overall survival in prostate cancer. Br J Cancer 99(9):1426-32, 2008. PMID: 18841158.
- Tsao CC, Teh BT, Jonasch E, Shreiber-Agus N, Efstathiou E, Hoang A, Czerniak B, Logothetis C, Corn PG. Inhibition of Mxi1 suppresses HIF-2alpha-dependent renal cancer tumorigenesis. Cancer Biol Ther 7(10):1619-27, 2008. e-Pub 2008. PMID: 19018165.
- Araujo J, Logothetis C. Targeting Src signaling in metastatic bone disease. Int J Cancer 124(1):1-6, 2008. PMID: 18942061.
- Liakou CI, Kamat A, Tang DN, Chen H, Sun J, Troncoso P, Logothetis C, Sharma P. CTLA-4 blockade increases IFNgamma-producing CD4+ICOShi cells to shift the ratio of effector to regulatory T cells in cancer patients. Proc Natl Acad Sci U S A 105(39):14987-92, 2008. PMID: 18818309.
- Chu K, Cheng CJ, Ye X, Lee YC, Zurita AJ, Chen DT, Yu-Lee LY, Zhang S, Yeh ET, Hu MC, Logothetis CJ, Lin SH. Cadherin-11 promotes the metastasis of prostate cancer cells to bone. Mol Cancer Res 6(8):1259-67, 2008. PMID: 18708358.
- Li ZG, Mathew P, Yang J, Starbuck MW, Zurita AJ, Liu J, Sikes C, Multani AS, Efstathiou E, Lopez A, Wang J, Fanning TV, Prieto VG, Kundra V, Vazquez ES, Troncoso P, Raymond AK, Logothetis CJ, Lin SH, Maity S, Navone NM. Androgen receptor-negative human prostate cancer cells induce osteogenesis in mice through FGF9-mediated mechanisms. J Clin Invest 118(8):2697-710, 2008. PMID: 18618013.
- Lin SH, Lee YC, Choueiri MB, Wen S, Mathew P, Ye X, Do KA, Navone NM, Kim J, Tu SM, Yu-Lee LY, Logothetis CJ. Soluble ErbB3 levels in bone marrow and plasma of men with prostate cancer. Clin Cancer Res 14(12):3729-36, 2008. PMID: 18559590.
- Lin SH, Cheng CJ, Lee YC, Ye X, Tsai WW, Kim J, Pasqualini R, Arap W, Navone NM, Tu SM, Hu M, Yu-Lee LY, Logothetis CJ. A 45-kDa ErbB3 secreted by prostate cancer cells promotes bone formation. Oncogene 27(39):5195-203, 2008. PMID: 18490922.
- Logothetis CJ, Navone NM, Lin SH. Understanding the biology of bone metastases: Key to the effective treatment of prostate cancer. Clin Cancer Res 14(6):1599-602, 2008. PMID: 18347159.
- McDonnell TJ, Chari NS, Cho-Vega JH, Troncoso P, Wang X, Bueso-Ramos CE, Coombes K, Brisbay S, Lopez R, Prendergast G, Logothetis C, Do KA. Biomarker expression patterns that correlate with high grade features in treatment naive, organ-confined prostate cancer. BMC Med Genomics 1:1, 2008. e-Pub 2008. PMID: 18237448.
- Thall PF, Wooten LH, Logothetis CJ, Millikan RE, Tannir NM. Bayesian and frequentist two-stage treatment strategies based on sequential failure times subject to interval censoring. Stat Med 26(26):4687-702, 2007. e-Pub 2007. PMID: 17427204.
- Mao S, Daliani DD, Wang X, Thall PF, Do KA, Perez CA, Brown MA, Bouchillon K, Carter CM, Logothetis CJ, Kim J. Employing the treatment-free interval of intermittent androgen ablation to screen candidate prostate cancer therapies. Prostate 67(15):1677-85, 2007. PMID: 17879948.
- Fizazi K, Le Maitre A, Hudes G, Berry WR, Kelly WK, Eymard JC, Logothetis CJ, Pignon JP, Michiels S, Meta-analysis of Estramustine in Prostate Cancer (MECaP) Trialists' Collaborative Group. Addition of estramustine to chemotherapy and survival of patients with castration-refractory prostate cancer: a meta-analysis of individual patient data. Lancet Oncol 8(11):994-1000, 2007. e-Pub 2007. PMID: 17942366.
- Thall PF, Logothetis C, Pagliaro LC, Wen S, Brown MA, Williams D, Millikan RE. Adaptive therapy for androgen-independent prostate cancer: a randomized selection trial of four regimens. J Natl Cancer Inst 99(21):1613-22, 2007. e-Pub 2007. PMID: 17971530.
- Mathew P, Thall PF, Bucana CD, Oh WK, Morris MJ, Jones DM, Johnson MM, Wen S, Pagliaro LC, Tannir NM, Tu SM, Meluch AA, Smith L, Cohen L, Kim SJ, Troncoso P, Fidler IJ, Logothetis CJ. Platelet-derived growth factor receptor inhibition and chemotherapy for castration-resistant prostate cancer with bone metastases. Clin Cancer Res 13(19):5816-24, 2007. PMID: 17908974.
- Li ZG, Yang J, Vazquez ES, Rose D, Vakar-Lopez F, Mathew P, Lopez A, Logothetis CJ, Lin SH, Navone NM. Low-density lipoprotein receptor-related protein 5 (LRP5) mediates the prostate cancer-induced formation of new bone. Oncogene 27(5):596-603, 2007. e-Pub 2007. PMID: 17700537.
- van Adelsberg J, Gann P, Ko AT, Damber JE, Logothetis C, Marberger M, Schmitz-Drager BJ, Tubaro A, Harms CJ, Roehrborn C. The VIOXX in prostate cancer prevention study: cardiovascular events observed in the rofecoxib 25 mg and placebo treatment groups. Curr Med Res Opin 23(9):2063-2070, 2007. e-Pub 2007. PMID: 17651539.
- Chen N, Ye XC, Chu K, Navone NM, Sage EH, Yu-Lee LY, Logothetis CJ, Lin SH. A Secreted Isoform of ErbB3 Promotes Osteonectin Expression in Bone and Enhances the Invasiveness of Prostate Cancer Cells. Cancer Res 67(14):6544-8, 2007. PMID: 17638862.
- Liakou CI, Narayanan S, Ng Tang D, Logothetis CJ, Sharma P. Focus on TILs: Prognostic significance of tumor infiltrating lymphocytes in human bladder cancer (Review). Cancer Immun 7:10 (Review), 2007. PMID: 17591743.
- Efstathiou E, Troncoso P, Wen S, Do KA, Pettaway CA, Pisters LL, McDonnell TJ, Logothetis CJ. Initial modulation of the tumor microenvironment accounts for thalidomide activity in prostate cancer. Clin Cancer Res 13(4):1224-31, 2007. PMID: 17317833.
- Tannir NM, Cohen L, Wang X, Thall P, Mathew PF, Jonasch E, Siefker-Radtke A, Pagliaro LC, Ng CS, Logothetis C. Improved tolerability and quality of life with maintained efficacy using twice-daily low-dose interferon-alpha-2b: results of a randomized phase II trial of low-dose versus intermediate-dose interferon-alpha-2b in patients with metastatic renal cell carcinoma. Cancer 107:2254-61, 2006. PMID: 17029276.
- Spurgers KB, Gold DL, Coombes KR, Bohnenstiehl NL, Mullins B, Meyn RE, Logothetis CJ, McDonnell TJ. Identification of Cell Cycle Regulatory Genes as Principal Targets of p53-mediated Transcriptional Repression. J Biol Chem 281(35):25134-42, 2006. PMID: 16798743.
- Mathew P, Logothetis CJ, Dieringer PY, Chen I, Pagliaro LC, Bekele BN, Zhou X, Daliani DD. Thalidomide/estramustine/paclitaxel in metastatic androgen-independent prostate cancer. Clin Genitourin Cancer 5(2):144-9, 2006. PMID: 17026803.
- Subbarayan V, Krieg P, Hsi LC, Kim J, Yang P, Sabichi AL, Llansa N, Mendoza G, Logothetis CJ, Newman RA, Lippman SM, Menter DG. 15-Lipoxygenase-2 gene regulation by its product 15-(S)-hydroxyeicosatetraenoic acid through a negative feedback mechanism that involves peroxisome proliferator-activated receptor gamma. Oncogene 25:6015-25, 2006. PMID: 16682954.
- Kim SJ, Uehara H, Yazici S, Busby JE, Nakamura T, He J, Maya M, Logothetis C, Mathew P, Wang X, Do KA, Fan D, Fidler IJ. Targeting platelet-derived growth factor receptor on endothelial cells of multidrug-resistant prostate cancer. J Natl Cancer Inst 98(11):783-93, 2006. PMID: 16757703.
- Wang J, Do KA, Wen S, Tsavachidis S, McDonnell TJ, Logothetis CJ, Coombes KR. Merging microarray data, robust feature selection, and predicting prognosis in prostate cancer. Cancer Inform 2:87-97, 2006. e-Pub 2007. PMID: 19458761.
- Leibovici D, Kamat AM, Pettaway CA, Pagliaro L, Rosser CJ, Logothetis C, Pisters LL. Cystoprostatectomy for effective palliation of symptomatic bladder invasion by prostate cancer. J Urol 174(6):2186-90, 2005. PMID: 16280761.
- Tu SM, Kim J, Pagliaro LC, Vakar-Lopez F, Wong FC, Wen S, General R, Podoloff DA, Lin SH, Logothetis CJ. Therapy tolerance in selected patients with androgen-independent prostate cancer following strontium-89 combined with chemotherapy. J Clin Oncol 23(31):7904-10, 2005. PMID: 16258090.
- Loberg RD, Logothetis CJ, Keller ET, Pienta KJ. Pathogenesis and treatment of prostate cancer bone metastases: targeting the lethal phenotype. J Clin Oncol 23(32):8232-41, 2005. PMID: 16278478.
- Strom SS, Wang X, Pettaway CA, Logothetis CJ, Yamamura Y, Do KA, Babaian RJ, Troncoso P. Obesity, weight gain, and risk of biochemical failure among prostate cancer patients following prostatectomy. Clin Cancer Res 11(19 Pt 1):6889-94, 2005. PMID: 16203779.
- Kim J, Yang P, Suraokar M, Sabichi AL, Llansa ND, Mendoza G, Subbarayan V, Logothetis CJ, Newman RA, Lippman SM, Menter DG. Suppression of prostate tumor cell growth by stromal cell prostaglandin D synthase-derived products. Cancer Res 65(14):6189-98, 2005. PMID: 16024620.
- Kim J, Sun P, Lam YW, Troncoso P, Sabichi AL, Babaian RJ, Pisters LL, Pettaway CA, Wood CG, Lippman SM, McDonnell TJ, Lieberman R, Logothetis C, Ho SM. Changes in serum proteomic patterns by presurgical alpha-tocopherol and L-selenomethionine supplementation in prostate cancer. Cancer Epidemiol Biomarkers Prev 14(7):1697-702, 2005. PMID: 16030104.
- Cho-Vega JH, Troncoso P, Do KA, Rago C, Wang X, Tsavachidis S, Medeiros LJ, Spurgers K, Logothetis C, McDonnell TJ. Combined laser capture microdissection and serial analysis of gene expression from human tissue samples. Mod Pathol 18(4):577-84, 2005. PMID: 15529182.
- Subbarayan V, Xu XC, Kim J, Yang P, Hoque A, Sabichi AL, Llansa N, Mendoza G, Logothetis CJ, Newman RA, Lippman SM, Menter DG. Inverse relationship between 15-lipoxygenase-2 and PPAR-gamma gene expression in normal epithelia compared with tumor epithelia. Neoplasia 7(3):280-93, 2005. PMID: 15799828.
- Wyatt RB, Sanchez-Ortiz RF, Wood CG, Ramirez E, Logothetis C, Pettaway CA. Prognostic factors for survival among Caucasian, African-American and Hispanic men with androgen-independent prostate cancer. J Natl Med Assoc 96(12):1587-93, 2004. PMID: 15622688.
- Subbarayan V, Sabichi AL, Kim J, Llansa N, Logothetis CJ, Lippman SM, Menter DG. Differential peroxisome proliferator-activated receptor-gamma isoform expression and agonist effects in normal and malignant prostate cells. Cancer Epidemiol Biomarkers Prev 13(11 Pt 1):1710-6, 2004. PMID: 15533897.
- Fizazi K, Culine S, Kramar A, Amato RJ, Bouzy J, Chen I, Droz JP, Logothetis CJ. Early predicted time to normalization of tumor markers predicts outcome in poor-prognosis nonseminomatous germ cell tumors. J Clin Oncol 22(19):3868-76, 2004. e-Pub 2004. PMID: 15302906.
- Assikis VJ, Do KA, Wen S, Wang X, Cho-Vega JH, Brisbay S, Lopez R, Logothetis CJ, Troncoso P, Papandreou CN, McDonnell TJ. Clinical and biomarker correlates of androgen-independent, locally aggressive prostate cancer with limited metastatic potential. Clin Cancer Res 10(20):6770-8, 2004. PMID: 15501953.
- Strom SS, Gu Y, Zhang H, Troncoso P, Babaian RJ, Pettaway CA, Shete S, Spitz MR, Logothetis CJ. Androgen receptor polymorphisms and risk of biochemical failure among prostatectomy patients. Prostate 60(4):343-51, 2004. PMID: 15264247.
- Fizazi K, Sikes CR, Kim J, Yang J, Martinez LA, Olive MC, Logothetis CJ, Navone NM. High efficacy of docetaxel with and without androgen deprivation and estramustine in preclinical models of advanced prostate cancer. Anticancer Res 24(5A):2897-903, 2004. PMID: 15517894.
- Papandreou CN, Logothetis CJ. Bortezomib as a potential treatment for prostate cancer. Cancer Res 64(15):5036-43, 2004. PMID: 15289299.
- Mathew P, Thall PF, Jones D, Perez C, Bucana C, Troncoso P, Kim SJ, Fidler IJ, Logothetis C. Platelet-derived growth factor receptor inhibitor imatinib mesylate and docetaxel: a modular phase I trial in androgen-independent prostate cancer. J Clin Oncol 22(16):3323-9, 2004. PMID: 15310776.
- Papandreou CN, Daliani DD, Nix D, Yang H, Madden T, Wang X, Pien CS, Millikan RE, Tu SM, Pagliaro L, Kim J, Adams J, Elliott P, Esseltine D, Petrusich A, Dieringer P, Perez C, Logothetis CJ. Phase I trial of the proteasome inhibitor bortezomib in patients with advanced solid tumors with observations in androgen-independent prostate cancer. J Clin Oncol 22(11):2108-21, 2004. PMID: 15169797.
- Salas TR, Kim J, Vakar-Lopez F, Sabichi AL, Troncoso P, Jenster G, Kikuchi A, Chen SY, Shemshedini L, Suraokar M, Logothetis CJ, DiGiovanni J, Lippman SM, Menter DG. Glycogen synthase kinase-3 beta is involved in the phosphorylation and suppression of androgen receptor activity. J Biol Chem 279(18):19191-200, 2004. e-Pub 2004. PMID: 14985354.
- Pisters LL, Pettaway CA, Troncoso P, McDonnell TJ, Stephens LC, Wood CG, Do KA, Brisbay SM, Wang X, Hossan EA, Evans RB, Soto C, Jacobson MG, Parker K, Merritt JA, Steiner MS, Logothetis CJ. Evidence that transfer of functional p53 protein results in increased apoptosis in prostate cancer. Clin Cancer Res 10(8):2587-93, 2004. PMID: 15102659.
- Mathew P, Fidler IJ, Logothetis CJ. Combination docetaxel and platelet-derived growth factor receptor inhibition with imatinib mesylate in prostate cancer. Semin Oncol 31:24-9, 2004. PMID: 15176001.
- Spurgers KB, Coombes KR, Meyn RE, Gold DL, Logothetis CJ, Johnson TJ, McDonnell TJ. A comprehensive assessment of p53-responsive genes following adenoviral-p53 gene transfer in Bcl-2-expressing prostate cancer cells. Oncogene 23(9):1712-23, 2004. PMID: 14647426.
- Scher HI, Eisenberger M, D'Amico AV, Halabi S, Small EJ, Morris M, Kattan MW, Roach M, Kantoff P, Pienta KJ, Carducci MA, Agus D, Slovin SF, Heller G, Kelly WK, Lange PH, Petrylak D, Berg W, Higano C, Wilding G, Moul JW, Partin AN, Logothetis C, Soule HR. Eligibility and outcomes reporting guidelines for clinical trials for patients in the state of a rising prostate-specific antigen: recommendations from the Prostate-Specific Antigen Working Group. J Clin Oncol 22(3):537-56, 2004. PMID: 14752077.
- Zurita AJ, Troncoso P, Cardo-Vila M, Logothetis CJ, Pasqualini R, Arap W. Combinatorial screenings in patients: the interleukin-11 receptor alpha as a candidate target in the progression of human prostate cancer. Cancer Res 64(2):435-9, 2004. PMID: 14744752.
- Siefker-Radtke AO, Walsh GL, Pisters LL, Shen Y, Swanson DA, Logothetis CJ, Millikan RE. Is there a role for surgery in the management of metastatic urothelial cancer? The M. D. Anderson experience. J Urol 171(1):145-8, 2004. PMID: 14665863.
- Williams S, Pettaway C, Song R, Papandreou C, Logothetis C, McConkey DJ. Differential effects of the proteasome inhibitor bortezomib on apoptosis and angiogenesis in human prostate tumor xenografts. Mol Cancer Ther 2(9):835-43, 2003. PMID: 14555702.
- Tu SM, Millikan RE, Pagliaro LC, Daliani D, Papandreou CN, Kim J, Chen DT, Williams DL, Logothetis CJ. Treatment of refractory urothelial carcinoma with alternating paclitaxel, methotrexate, cisplatin (TMP) and 5-fluorouracil, alpha-interferon, cisplatin (FAP). Urol Oncol 21(5):342-8, 2003. PMID: 14670540.
- Logothetis CJ. Foundation for the integration of biologically based therapy in the management of prostate cancer. Prostate 57(1):32-8, 2003. PMID: 12886521.
- Fizazi K, Yang J, Peleg S, Sikes CR, Kreimann EL, Daliani D, Olive M, Raymond KA, Janus TJ, Logothetis CJ, Karsenty G, Navone NM. Prostate cancer cells-osteoblast interaction shifts expression of growth/survival-related genes in prostate cancer and reduces expression of osteoprotegerin in osteoblasts. Clin Cancer Res 9(7):2587-97, 2003. PMID: 12855635.
- Pagliaro LC, Delpassand ES, Williams D, Millikan RE, Tu SM, Logothetis CJ. A Phase I/II study of strontium-89 combined with gemcitabine in the treatment of patients with androgen independent prostate carcinoma and bone metastases. Cancer 97(12):2988-94, 2003. PMID: 12784333.
- Bruckheimer EM, Spurgers K, Weigel NL, Logothetis C, McDonnell TJ. Regulation of Bcl-2 expression by dihydrotestosterone in hormone sensitive LNCaP-FGC prostate cancer cells. J Urol 169(4):1553-7, 2003. PMID: 12629413.
- Uehara H, Kim SJ, Karashima T, Shepherd DL, Fan D, Tsan R, Killion JJ, Logothetis C, Mathew P, Fidler IJ. Effects of blocking platelet-derived growth factor-receptor signaling in a mouse model of experimental prostate cancer bone metastases. J Natl Cancer Inst 95(6):458-70, 2003. PMID: 12644539.
- Millikan R, Thall PF, Lee SJ, Jones D, Cannon MW, Kuebler JP, Wade J, 3rd, Logothetis CJ. Randomized, multicenter, phase II trial of two multicomponent regimens in androgen-independent prostate cancer. J Clin Oncol 21(5):878-83, 2003. PMID: 12610188.
- Logothetis C, Tu SM, Navone N. Targeting prostate cancer bone metastases. Cancer 97(3):785-8, 2003. PMID: 12548576.
- Daliani DD, Assikis V, Tu SM, Papandreou CN, Pagliaro LC, Holtkamp T, Wang X, Thall PF, Logothetis CJ. Phase II trial of cyclophosphamide, vincristine, and dexamethasone in the treatment of androgen-independent prostate carcinoma. Cancer 97(3):561-7, 2003. PMID: 12548597.
- Pentz RD, Flamm AL, Pasqualini R, Logothetis CJ, Arap W. Revisiting ethical guidelines for research with terminal wean and brain-dead participants. Hastings Cent Rep 33(1):20-6, 2003. PMID: 12613384.
- Mintz PJ, Kim J, Do KA, Wang X, Zinner RG, Cristofanilli M, Arap MA, Hong WK, Troncoso P, Logothetis CJ, Pasqualini R, Arap W. Fingerprinting the circulating repertoire of antibodies from cancer patients. Nat Biotechnol 21(1):57-63, 2003. e-Pub 2002. PMID: 12496764.
- Kim J, Millikan RE, Smith TL, Tu SM, Pagliaro LC, Logothetis CJ. Treating refractory advanced or metastatic urothelial carcinoma with interleukin-2: a phase II study. Urol Oncol 21(1):21-6, 2003. PMID: 12684123.
- Volpert O, Luo W, Liu TJ, Estrera VT, Logothetis C, Lin SH. Inhibition of prostate tumor angiogenesis by the tumor suppressor CEACAM1. J Biol Chem 277(38):35696-702, 2002. PMID: 12122002.
- Pu YS, Do KA, Luo W, Logothetis CJ, Lin SH. Enhanced suppression of prostate tumor growth by combining C-CAM1 gene therapy and angiogenesis inhibitor TNP-470. Anticancer Drugs 13(7):743-9, 2002. PMID: 12187331.
- Martinez LA, Yang J, Vazquez ES, Rodriguez-Vargas Mdel C, Olive M, Hsieh JT, Logothetis CJ, Navone NM. p21 modulates threshold of apoptosis induced by DNA-damage and growth factor withdrawal in prostate cancer cells. Carcinogenesis 23(8):1289-96, 2002. PMID: 12151346.
- Logothetis CJ. Challenge of locally persistent prostate cancer: an unresolved clinical dilemma. J Clin Oncol 20(15):3187, 2002. PMID: 12149287.
- Papandreou CN, Daliani DD, Thall PF, Tu SM, Wang X, Reyes A, Troncoso P, Logothetis CJ. Results of a phase II study with doxorubicin, etoposide, and cisplatin in patients with fully characterized small-cell carcinoma of the prostate. J Clin Oncol 20(14):3072-80, 2002. PMID: 12118020.
- Pagliaro LC, Millikan RE, Tu SM, Williams D, Daliani D, Papandreou CN, Logothetis CJ. Cisplatin, gemcitabine, and ifosfamide as weekly therapy: a feasibility and phase II study of salvage treatment for advanced transitional-cell carcinoma. J Clin Oncol 20(13):2965-70, 2002. PMID: 12089226.
- Tu SM, Reyes A, Maa A, Bhowmick D, Pisters LL, Pettaway CA, Lin SH, Troncoso P, Logothetis CJ. Prostate carcinoma with testicular or penile metastases. Clinical, pathologic, and immunohistochemical features. Cancer 94(10):2610-7, 2002. PMID: 12173328.
- Fizazi K, Prow DM, Do KA, Wang X, Finn L, Kim J, Daliani D, Papandreou CN, Tu SM, Millikan RE, Pagliaro LC, Logothetis CJ, Amato RJ. Alternating dose-dense chemotherapy in patients with high volume disseminated non-seminomatous germ cell tumours. Br J Cancer 86(10):1555-60, 2002. PMID: 12085204.
- Siefker-Radtke AO, Millikan RE, Tu SM, Moore DF, Jr, Smith TL, Williams D, Logothetis CJ. Phase III trial of fluorouracil, interferon alpha-2b, and cisplatin versus methotrexate, vinblastine, doxorubicin, and cisplatin in metastatic or unresectable urothelial cancer. J Clin Oncol 20(5):1361-7, 2002. PMID: 11870180.
- Fizazi K, Martinez LA, Sikes CR, Johnston DA, Stephens LC, McDonnell TJ, Logothetis CJ, Trapman J, Pisters LL, Ordonez NG, Troncoso P, Navone NM. The association of p21((WAF-1/CIP1)) with progression to androgen-independent prostate cancer. Clin Cancer Res 8(3):775-81, 2002. PMID: 11895908.
- Plonowski A, Schally AV, Nagy A, Groot K, Krupa M, Navone NM, Logothetis C. Inhibition of in vivo proliferation of MDA-PCa-2b human prostate cancer by a targeted cytotoxic analog of luteinizing hormone-releasing hormone AN-207. Cancer Lett 176(1):57-63, 2002. PMID: 11790454.
- Arap W, Kolonin MG, Trepel M, Lahdenranta J, Cardo-Vila M, Giordano RJ, Mintz PJ, Ardelt PU, Yao VJ, Vidal CI, Chen L, Flamm A, Valtanen H, Weavind LM, Hicks ME, Pollock RE, Botz GH, Bucana CD, Koivunen E, Cahill D, Troncoso P, Baggerly KA, Pentz RD, Do KA, Logothetis CJ, Pasqualini R. Steps toward mapping the human vasculature by phage display. Nat Med 8(2):121-7, 2002. PMID: 11821895.
- Pu, Y-S, Do K-A, Luo W, Logothetis CJ, Lin S-H . Enhanced suppression of prostate tumor growth by combining C-CAM1 gene therapy and angiogenesis inhibitor TNP-470. Anti-Cancer Drugs 13:1-8, 2002.
- Fizazi K, Do KA, Wang X, Finn L, Logothetis CJ, Amato RJ. A 20% dose reduction of the original CISCA/VB regimen allows better tolerance and similar survival rate in disseminated testicular non-seminomatous germ-cell tumors: final results of a phase III randomized trial. Ann Oncol 13(1):125-34, 2002. PMID: 11863094.
- Coombes KR, Zhang L, Bueso-Ramos C, Brisbay S, Logothetis C, Roth J, Keating MJ, McDonnell TJ. TAD: a web interface and database for tissue microarrays. Appl Bioinformatics 1(3):155-8, 2002. PMID: 15130842.
- Newman RA, Yang J, Raymond M, Finlay V, Cabral F, Vourloumis D, Stephens LC, Troncoso P, Wu X, Logothetis CJ, Nicolaou KC, Navone NM. Antitumor efficacy of 26-fluoroepothilone B against human prostate cancer xenografts. Cancer Chemother Pharmacol 48(4):319-26, 2001. PMID: 11710633.
- Millikan R, Dinney C, Swanson D, Sweeney P, Ro JY, Smith TL, Williams D, Logothetis C. Integrated therapy for locally advanced bladder cancer: final report of a randomized trial of cystectomy plus adjuvant M-VAC versus cystectomy with both preoperative and postoperative M-VAC. J Clin Oncol 19(20):4005-13, 2001. PMID: 11600601.
- Honda T, Gjertsen BT, Spurgers KB, Briones F, Lee SJ, Hobbs ML, Meyn RE, Roth JA, Logothetis C, McDonnell TJ. Restoration of bax in prostate cancer suppresses tumor growth and augments therapeutic cell death induction. Anticancer Res 21(5):3141-6, 2001. PMID: 11848465.
- Fizazi K, Amato RJ, Beuzeboc P, Petit N, Bouhour D, Thiss A, Rebischung C, Chevreau C, Logothetis CJ, Droz JP. Germ cell tumors in patients infected by the human immunodeficiency virus. Cancer 92(6):1460-7, 2001. PMID: 11745223.
- Yang J, Fizazi K, Peleg S, Sikes CR, Raymond AK, Jamal N, Hu M, Olive M, Martinez LA, Wood CG, Logothetis CJ, Karsenty G, Navone NM. Prostate cancer cells induce osteoblast differentiation through a Cbfa1-dependent pathway. Cancer Res 61(14):5652-9, 2001. PMID: 11454720.
- Millikan RE, Plunkett WK, Smith TL, Williams DL, Logothetis CJ. Gemcitabine modulation of alkylator therapy: a phase I trial of escalating gemcitabine added to fixed doses of ifosfamide and doxorubicin. Cancer 92(1):194-9, 2001. PMID: 11443627.
- Millikan R, Baez L, Banerjee T, Wade J, Edwards K, Winn R, Smith TL, Logothetis C. Randomized phase 2 trial of ketoconazole and ketoconazole/doxorubicin in androgen independent prostate cancer. Urol Oncol 6(3):111-115, 2001. PMID: 11344001.
- Logothetis CJ, Wu KK, Finn LD, Daliani D, Figg W, Ghaddar H, Gutterman JU. Phase I trial of the angiogenesis inhibitor TNP-470 for progressive androgen-independent prostate cancer. Clin Cancer Res 7(5):1198-203, 2001. PMID: 11350884.
- Tu SM, Millikan RE, Mengistu B, Delpassand ES, Amato RJ, Pagliaro LC, Daliani D, Papandreou CN, Smith TL, Kim J, Podoloff DA, Logothetis CJ. Bone-targeted therapy for advanced androgen-independent carcinoma of the prostate: a randomised phase II trial. Lancet 357(9253):336-41, 2001. PMID: 11210994.
- Schumacher G, Bruckheimer EM, Beham AW, Honda T, Brisbay S, Roth JA, Logothetis C, McDonnell TJ. Molecular determinants of cell death induction following adenovirus-mediated gene transfer of wild-type p53 in prostate cancer cells. Int J Cancer 91(2):159-66, 2001. PMID: 11146439.
- Millikan, RE, Baez L, Banerjee T, Wade J, Edwards K, Winn R, Smith TL, Logothetis C. Randomized phase 2 trial of ketoconazole and ketoconazole /doxorubicin in androgen independent prostate cancer. . Urologic Oncology 6(3):111-115, 2001. PMID: 11344001.
- Pagliaro L, Daliani D, Amato R, Tu SM, Jones D, Smith T, Logothetis C, Millikan R. A Phase II trial of bryostatin-1 for patients with metastatic renal cell carcinoma. Cancer 89(3):615-8, 2000. PMID: 10931461.
- Ozen M, Hopwood VL, Balbay MD, Johnston DA, Babaian RJ, Logothetis CJ, von Eschenbach AC, Pathak S. Correlation of non-random chromosomal aberrations in lymphocytes of prostate cancer patients with specific clinical parameters. Int J Oncol 17(1):113-7, 2000. PMID: 10853027.
- Kim J, Palmer JL, Finn L, Hodges S, Bowes VV, Deftos L, Murphy G, Logothetis C. The pattern of serum markers in patients with androgen-independent adenocarcinoma of the prostate. Urol Oncol 5(3):97-103, 2000. PMID: 10765015.
- Pettaway CA, Pisters LL, Troncoso P, Slaton J, Finn L, Kamoi K, Logothetis CJ. Neoadjuvant chemotherapy and hormonal therapy followed by radical prostatectomy: feasibility and preliminary results. J Clin Oncol 18(5):1050-7, 2000. PMID: 10694556.
- Navone NM, Rodriquez-Vargas MC, Benedict WF, Troncoso P, McDonnell TJ, Zhou JH, Luthra R, Logothetis CJ. TabBO: a model reflecting common molecular features of androgen-independent prostate cancer. Clin Cancer Res 6(3):1190-7, 2000. PMID: 10741751.
- Lecrone V, Li W, Devoll RE, Logothetis C, Farach-Carson MC. Calcium signals in prostate cancer cells: specific activation by bone-matrix proteins. Cell Calcium 27(1):35-42, 2000. PMID: 10726209.
- Amato RJ, Millikan R, Daliani D, Wood L, Logothetis C, Pollack A. Cyclophosphamide and carboplatin and selective consolidation in advanced seminoma. Clin Cancer Res 6(1):72-7, 2000. PMID: 10656434.
- McCutcheon IE, Eng DY, Logothetis CJ. Brain metastasis from prostate carcinoma: antemortem recognition and outcome after treatment. Cancer 86(11):2301-11, 1999. PMID: 10590371.
- Pisters LL, Pettaway CA, Hossan E, Evans R, Steiner MS, Wood CG, Troncoso P, McDonnell TJ, Fenstenmacher MJ, Logothetis CJ. Intraprostatic AD-p53 gene therapy followed by radical prostatectomy: feasibility and preliminary results. Prostate Cancer Prostatic Dis 2(S3):S27, 1999. PMID: 12496806.
- Park DS, Prow DM, Amato RJ, Logothetis CJ. Management consideration in nonpulmonary visceral metastatic seminoma of testis. J Korean Med Sci 14(4):431-7, 1999. PMID: 10485624.
- Logothetis CJ. Introduction: a therapeutically relevant framework for the classification of human prostate cancer. Semin Oncol 26(4):369-74, 1999. PMID: 10482179.
- Luo W, Tapolsky M, Earley K, Wood CG, Wilson DR, Logothetis CJ, Lin SH. Tumor-suppressive activity of CD66a in prostate cancer. Cancer Gene Ther 6(4):313-21, 1999. PMID: 10419049.
- Park DS, Prow DM, Amato RJ, Ro JY, Logothetis CJ. Clinical characteristics of metachronous bilateral testicular tumors in the chemotherapeutic era. Yonsei Med J 40(2):137-43, 1999. PMID: 10333717.
- Horti J, Dixon SC, Logothetis CJ, Guo Y, Reed E, Figg WD. Increased transcriptional activity of prostate-specific antigen in the presence of TNP-470, an angiogenesis inhibitor. Br J Cancer 79(9):1588-93, 1999. PMID: 10188911.
- Amato RJ, Bui C, Logothetis CJ. Estramustine in combination with vinblastine and mitomycin-C for patients with progressive androgen independent adenocarcinoma of the prostate. Prostate Cancer Prostatic Dis 2(2):83-87, 1999. PMID: 12496843.
- Ozen M, Hopwood VL, Johnston DA, Babaian RJ, Logothetis CJ, von Eschenbach AC, Pathak S. Aneuploidy index in blood: a potential marker for early onset, androgen response, and metastasis in human prostate cancer. Urology 53(2):381-5, 1999. PMID: 9933059.
- Czerniak B, Chaturvedi V, Li L, Hodges S, Johnston D, Roy JY, Luthra R, Logothetis C, Von Eschenbach AC, Grossman HB, Benedict WF, Batsakis JG. Superimposed histologic and genetic mapping of chromosome 9 in progression of human urinary bladder neoplasia: implications for a genetic model of multistep urothelial carcinogenesis and early detection of urinary bladder cancer. Oncogene 18(5):1185-96, 1999. PMID: 10022124.
- Navone NM, Labate ME, Troncoso P, Pisters LL, Conti CJ, von Eschenbach AC, Logothetis CJ. p53 mutations in prostate cancer bone metastases suggest that selected p53 mutants in the primary site define foci with metastatic potential. J Urol 161(1):304-8, 1999. PMID: 10037428.
- Lin SH, Pu YS, Luo W, Wang Y, Logothetis CJ. Schedule-dependence of C-CAM1 adenovirus gene therapy in a prostate cancer model. Anticancer Res 19(1A):337-40, 1999. PMID: 10226564.
- Herrmann JL, Briones F, Jr, Brisbay S, Logothetis CJ, McDonnell TJ. Prostate carcinoma cell death resulting from inhibition of proteasome activity is independent of functional Bcl-2 and p53. Oncogene 17(22):2889-99, 1998. PMID: 9879995.
- Ozen M, Navone NM, Multani AS, Troncoso P, Logothetis CJ, Chung LW, von Eschenbach AC, Pathak S. Structural alterations of chromosome 5 in twelve human prostate cancer cell lines. Cancer Genet Cytogenet 106(2):105-9, 1998. PMID: 9797773.
- Logothetis CJ. Emerging strategies in the treatment of testis cancer. Curr Opin Urol 8(5):411-2, 1998. PMID: 17039021.
- Millikan RE, Logothetis CJ. Prospects for optimized clinical management of bladder cancer by application of phenotypic markers. J Natl Cancer Inst 90(14):1028-9, 1998. PMID: 9672249.
- Tu SM, Pagliaro LC, Banks ME, Amato RJ, Millikan RE, Bugazia NA, Madden T, Newman RA, Logothetis CJ. Phase I study of suramin combined with doxorubicin in the treatment of androgen-independent prostate cancer. Clin Cancer Res 4(5):1193-201, 1998. PMID: 9607577.
- Logothetis CJ. Biologic foundation of the therapy for advanced germ cell tumors. Semin Urol Oncol 16(2):62-4, 1998. PMID: 9649228.
- Moss, TJ, Logothetis CJ, Wood CG. Immunocytochemical (ICC) analysis: An attractive alternative to reverse transcriptase-polymerase chain reaction (RT-PCR) in molecular staging of prostate cancer (PCa). . J Urol 159(5):292, 1998.
- Navone NM, Olive M, Ozen M, Davis R, Troncoso P, Tu SM, Johnston D, Pollack A, Pathak S, von Eschenbach AC, Logothetis CJ. Establishment of two human prostate cancer cell lines derived from a single bone metastasis. Clin Cancer Res 3(12 Pt 1):2493-500, 1997. PMID: 9815652.
- Ellerhorst JA, Tu SM, Amato RJ, Finn L, Millikan RE, Pagliaro LC, Jackson A, Logothetis CJ. Phase II trial of alternating weekly chemohormonal therapy for patients with androgen-independent prostate cancer. Clin Cancer Res 3(12 Pt 1):2371-6, 1997. PMID: 9815636.
- Ellerhorst JA, Sella A, Amato RJ, Tu SM, Millikan RE, Finn LD, Banks M, Logothetis CJ. Phase II trial of 5-fluorouracil, interferon-alpha and continuous infusion interleukin-2 for patients with metastatic renal cell carcinoma. Cancer 80(11):2128-32, 1997. PMID: 9392335.
- Millikan R, Logothetis C. Update of the NCCN guidelines for treatment of prostate cancer. Oncology (Williston Park) 11(11A):180-93, 1997. PMID: 9430189.
- Hu SX, Ji W, Zhou Y, Logothetis C, Xu HJ. Development of an adenovirus vector with tetracycline-regulatable human tumor necrosis factor alpha gene expression. Cancer Res 57(16):3339-43, 1997. PMID: 9269991.
- Chaturvedi V, Li L, Hodges S, Johnston D, Ro JY, Logothetis C, von Eschenbach AC, Batsakis JG, Czerniak B. Superimposed histologic and genetic mapping of chromosome 17 alterations in human urinary bladder neoplasia. Oncogene 14(17):2059-70, 1997. PMID: 9160886.
- McDonnell TJ, Navone NM, Troncoso P, Pisters LL, Conti C, von Eschenbach AC, Brisbay S, Logothetis CJ. Expression of bcl-2 oncoprotein and p53 protein accumulation in bone marrow metastases of androgen independent prostate cancer. J Urol 157(2):569-74, 1997. PMID: 8996359.
- Sim SJ, Glassman AB, Ro JY, Lee JJ, Logothetis CJ, Liu FJ. Serum calcitonin in small cell carcinoma of the prostate. Ann Clin Lab Sci 26(6):487-95, 1996. PMID: 8908318.
- Tu SM, Delpassand ES, Jones D, Amato RJ, Ellerhorst J, Logothetis CJ. Strontium-89 combined with doxorubicin in the treatment of patients with androgen-independent prostate cancer. Urol Oncol 2(6):191-7, 1996. PMID: 21224168.
- Hutter RV, Montie JE, Busch C, Crignon DJ, Lieber M, Logothetis C, Ragde H, Reuter VE. Current prognostic factors and their relevance to staging. Cancer 78(2):369-71, 1996. PMID: 8674020.
- Logothetis C, Swanson D, Amato R, Banks M, Finn L, Ayala A, Ro J, Babaian R, Dinney C, Ellerhorst J, Hall C, von Eschenbach A. Optimal delivery of perioperative chemotherapy: preliminary results of a randomized, prospective, comparative trial of preoperative and postoperative chemotherapy for invasive bladder carcinoma. J Urol 155(4):1241-5, 1996. PMID: 8632540.
- Herrada J, Dieringer P, Logothetis CJ. Characterization of patients with androgen-independent prostatic carcinoma whose serum prostate specific antigen decreased following flutamide withdrawal. J Urol 155(2):620-3, 1996. PMID: 8558675.
- Logothetis CJ. Chemotherapy for invasive and metastatic bladder cancer. . Advances in Oncology 12(1):19-22, 1996.
- Hoosein, N, Abdul M, Logothetis CJ. Significance of neuroendocrine differentiation in prostatic carcinoma. The Cancer Journal 9(6):291-295, 1996.
- Amato, RJ, Ellerhorst J, Finn L, Logothetis CJ. Absence of anti-tumor activity with Prednisone in patients with progressive androgen-independent prostate carcinoma. Urologic Oncology 2(2):70-3, 1996. PMID: 21224139.
- Amato RJ, Ellerhorst J, Banks M, Logothetis CJ. Carboplatin and ifosfamide and selective consolidation in advanced seminoma. Eur J Cancer 31A(13):2223-8, 1995. PMID: 8652247.
- Tu SM, Hossan E, Amato R, Kilbourn R, Logothetis CJ. Paclitaxel, cisplatin and methotrexate combination chemotherapy is active in the treatment of refractory urothelial malignancies. J Urol 154(5):1719-22, 1995. PMID: 7563331.
- Amato R, Meyers C, Ellerhorst J, Finn L, Kilbourn R, Sella A, Logothetis C. A phase I trial of intermittent high-dose alpha-interferon and dexamethasone in metastatic renal cell carcinoma. Ann Oncol 6(9):911-4, 1995. PMID: 8624294.
- Logothetis CJ, Finn LD, Smith T, Kilbourn RG, Ellerhorst JA, Zukiwski AA, Sella A, Tu SM, Amato RJ. Escalated MVAC with or without recombinant human granulocyte-macrophage colony-stimulating factor for the initial treatment of advanced malignant urothelial tumors: results of a randomized trial. J Clin Oncol 13(9):2272-7, 1995. PMID: 7666085.
- Hoosein NM, Martin KJ, Abdul M, Logothetis CJ, Kaddurah-Daouk R. Antiproliferative effects of cyclocreatine on human prostatic carcinoma cells. Anticancer Res 15(4):1339-42, 1995. PMID: 7654018.
- Abdul M, Logothetis CJ, Hoosein NM. Growth-inhibitory effects of serotonin uptake inhibitors on human prostate carcinoma cell lines. J Urol 154(1):247-50, 1995. PMID: 7776439.
- Tu SM, Robinson ED, Amato RJ, Ellerhorst JA, Kilbourn RG, Logothetis CJ. A phase I study of FAP (5-Fluorouracil, α-interferon and cisplatin) combined with methotrexate for the treatment of advanced urothelial malignancies. Urol Oncol 1(4):156-60, 1995. PMID: 21224110.
- Amato RJ, Ellerhorst J, Bui C, Logothetis CJ. Estramustine and vinblastine for patients with progressive androgen-independent adenocarcinoma of the prostate. Urol Oncol 1(4):168-72, 1995. PMID: 21224113.
- Sternberg CN, Raghaven D, Ohi Y, Bajorin D, Herr H, Kato T, Kuroda M, Logothetis CH, Scher H, Splinter TA. Neoadjuvant and adjuvant chemotherapy in advanced disease--what are the effects on survival and prognosis?. Int J Urol 2(2):76-88, 1995. PMID: 7553308.
- Kilbourn RG, Fonseca GA, Griffith OW, Ewer M, Price K, Striegel A, Jones E, Logothetis CJ. NG-methyl-L-arginine, an inhibitor of nitric oxide synthase, reverses interleukin-2-induced hypotension. Crit Care Med 23(6):1018-24, 1995. PMID: 7774211.
- Daliani DD, Eisenberg PD, Weems J, Lord R, Fueger R, Logothetis CJ. The results of a phase II randomized trial comparing 5-fluorouracil and 5-fluorouracil plus alpha-interferon: observations on the design of clinical trials for androgen-independent prostate cancer. J Urol 153(5):1587-91, 1995. PMID: 7536271.
- Fornage BD, Logothetis CJ, Swanson DA, Ro JY. Bilateral testicular metastases from prostate carcinoma: gray-scale and color Doppler sonographic findings. J Ultrasound Med 14(3):247-9, 1995. PMID: 7760471.
- Sella A, Aggarwal BB, Kilbourn RG, Bui CA, Zukiwski AA, Logothetis CJ. Phase I study of tumor necrosis factor plus actinomycin D in patients with androgen-independent prostate cancer. Cancer Biother 10(3):225-35, 1995. PMID: 8547961.
- Nazario, A, Amato RJ, Hutchinson L, Bui C, Ellerhorst J, Logothetis CJ. Paclitaxel in extensively pretreated nonseminomatous germ cell tumors. Urologic Oncology 1(5):184-7, 1995. PMID: 21224115.
- Hsieh, JT, Wu HC, Wang Y, Song WT, Li W, Finn L, Logothetis CJ. Evidence for the existence of an organ-specific androgen-independent pathway of progression in patients with metastatic prostate cancer. Urologic Oncology 1(2):67-72, 1995. PMID: 21224094.
- Hoosein, N, Abdul M, McCabe R, Gero E, Deftos L, Banks M, Hodges S, Finn L, Logothetis CJ. Clinical significance of elevation in neuroendocrine factors and interleukin-6 in metastatic prostate cancer. Urologic Oncology 1(6):246-51, 1995. PMID: 21224126.
- Abdul, M, Hsieh J-T, Logothetis CJ, Hoosein NM. Secretion of prostate-specific antigen-suppressing activity by two human prostate carcinoma cell lines. Urologic Oncology 1(1):38-41, 1995. PMID: 21224088.
- Logothetis CJ, Hossan EA, Smith TL. SMS 201-995 in the treatment of refractory prostatic carcinoma. Anticancer Res 14(6B):2731-4, 1994. PMID: 7872709.
- Mitropoulos D, Dimopoulos MA, Kiroudi-Voulgari A, Zervas A, Dimopoulos C, Logothetis CJ. Neoadjuvant cisplatin and interferon-alpha 2B in the treatment and organ preservation of penile carcinoma. J Urol 152(4):1124-6, 1994. PMID: 8072080.
- Logothetis CJ, Hoosein NM, Hsieh JT. The clinical and biological study of androgen independent prostate cancer (AI PCa). Semin Oncol 21(5):620-9, 1994. PMID: 7524155.
- Crawford ED, Kozlowski JM, Debruyne FM, Fair WR, Logothetis CJ, Balmer C, Robinson RG, Porter AT, Kirk D. The use of strontium 89 for palliation of pain from bone metastases associated with hormone-refractory prostate cancer. Urology 44(4):481-5, 1994. PMID: 7524233.
- Ellerhorst JA, Kilbourn RG, Amato RJ, Zukiwski AA, Jones E, Logothetis CJ. Phase II trial of low dose gamma-interferon in metastatic renal cell carcinoma. J Urol 152(3):841-5, 1994. PMID: 8051732.
- Logothetis CJ, Hossan E, Recondo G, Sella A, Ellerhorst J, Kilbourn R, Zukiwski A, Amato R. 5-Fluorouracil and interferon-alpha in chemotherapy refractory bladder carcinoma: an effective regimen. Anticancer Res 14(3B):1265-9, 1994. PMID: 8067694.
- Abdul M, Anezinis PE, Logothetis CJ, Hoosein NM. Growth inhibition of human prostatic carcinoma cell lines by serotonin antagonists. Anticancer Res 14(3A):1215-20, 1994. PMID: 8074475.
- Sella A, Kilbourn R, Amato R, Bui C, Zukiwski AA, Ellerhorst J, Logothetis CJ. Phase II study of ketoconazole combined with weekly doxorubicin in patients with androgen-independent prostate cancer. J Clin Oncol 12(4):683-8, 1994. PMID: 7512126.
- Dimopoulos MA, Finn L, Logothetis CJ. Pattern of failure and survival of patients with metastatic urothelial tumors relapsing after cis-platinum-based chemotherapy. J Urol 151(3):598-600; discussion 600-1, 1994. PMID: 8308966.
- Sella A, Kilbourn RG, Gray I, Finn L, Zukiwski AA, Ellerhorst J, Amato RJ, Logothetis CJ. Phase I study of interleukin-2 combined with interferon-alpha and 5-fluorouracil in patients with metastatic renal cell cancer. Cancer Biother 9(2):103-11, 1994. PMID: 7812360.
- Hoosein NM, Logothetis CJ, Chung LW. Differential effects of peptide hormones bombesin, vasoactive intestinal polypeptide and somatostatin analog RC-160 on the invasive capacity of human prostatic carcinoma cells. J Urol 149(5):1209-13, 1993. PMID: 8097794.
- Dimopoulos MA, Logothetis CJ, Markowitz A, Sella A, Amato R, Ro J. Collecting duct carcinoma of the kidney. Br J Urol 71(4):388-91, 1993. PMID: 8499979.
- Sella A, Swanson DA, Ro JY, Putnam JB, Jr, Amato RJ, Markowitz AB, Logothetis CJ. Surgery following response to interferon-alpha-based therapy for residual renal cell carcinoma. J Urol 149(1):19-21; discussion 21-2, 1993. PMID: 8417208.
- McDonnell TJ, Troncoso P, Brisbay SM, Logothetis C, Chung LW, Hsieh JT, Tu SM, Campbell ML. Expression of the protooncogene bcl-2 in the prostate and its association with emergence of androgen-independent prostate cancer. Cancer Res 52(24):6940-4, 1992. PMID: 1458483.
- Logothetis CJ, Xu HJ, Ro JY, Hu SX, Sahin A, Ordonez N, Benedict WF. Altered expression of retinoblastoma protein and known prognostic variables in locally advanced bladder cancer. J Natl Cancer Inst 84(16):1256-61, 1992. PMID: 1640485.
- Sella A, Logothetis CJ, Fitz K, Dexeus FH, Amato R, Kilbourn R, Wallace S. Phase II study of interferon-alpha and chemotherapy (5-fluorouracil and mitomycin C) in metastatic renal cell cancer. J Urol 147(3):573-7, 1992. PMID: 1538431.
- Giralt SA, Dexeus F, Amato R, Sella A, Logothetis C. Hyperthyroidism in men with germ cell tumors and high levels of beta-human chorionic gonadotropin. Cancer 69(5):1286-90, 1992. PMID: 1371235.
- Amato RJ, Logothetis CJ, Hallinan R, Ro JY, Sella A, Dexeus FH. Chemotherapy for small cell carcinoma of prostatic origin. J Urol 147(3):935-7, 1992. PMID: 1311396.
- Wishnow KI, Levinson AK, Johnson DE, Tenney DM, Grignon DJ, Ro JY, Ayala AJ, Logothetis CJ, Swanson DA, Babaian RJ, et al. Stage B (P2/3A/N0) transitional cell carcinoma of bladder highly curable by radical cystectomy. Urology 39(1):12-6, 1992. PMID: 1728789.
- Sella, A, Amato RJ, Fitz K, Kilbourn RG, Logothetis, CJ. Interferon-alpha and 5-fluorouracil Combination Chemotherapy for Metastatic Renal Cell Cancer. Inter and Cyto 20, 1992. PMID: 1538431.
- Logothetis CJ. Chemotherapy resistant transitional cell carcinoma as a target for chemoprevention. J Cell Biochem Suppl 16I:128-31, 1992. PMID: 1305675.
- Grignon DJ, Ro JY, Ayala AG, Shum DT, Ordonez NG, Logothetis CJ, Johnson DE, Mackay B. Small cell carcinoma of the urinary bladder. A clinicopathologic analysis of 22 cases. Cancer 69(2):527-36, 1992. PMID: 1309435.
- Chung LW, Li W, Gleave ME, Hsieh JT, Wu HC, Sikes RA, Zhau HE, Bandyk MG, Logothetis CJ, Rubin JS, et al. Human prostate cancer model: roles of growth factors and extracellular matrices. J Cell Biochem Suppl 16H:99-105, 1992. PMID: 1289680.
- Dexeus FH, Logothetis CJ, Sella A, Amato R, Kilbourn R, Fitz K, Striegel A. Combination chemotherapy with methotrexate, bleomycin and cisplatin for advanced squamous cell carcinoma of the male genital tract. J Urol 146(5):1284-7, 1991. PMID: 1719241.
- Sella A, el Naggar A, Ro JY, Dexeus FH, Amato RJ, Lee JS, Finn L, Logothetis CJ. Evidence of malignant features in histologically mature teratoma. J Urol 146(4):1025-8, 1991. PMID: 1680200.
- Dimopoulos MA, Amato RJ, Logothetis CJ. Predictive factors for effective salvage therapy of nonseminomatous germ cell tumors of testis. Urology 38(4):351-4, 1991. PMID: 1661457.
- Logothetis CJ. Organ preservation in bladder carcinoma: a matter of selection. J Clin Oncol 9(9):1525-6, 1991. PMID: 1875215.
- Dexeus FH, Logothetis CJ, Sella A, Amato R, Kilbourn R, Ogden S, Striegel A, Kwan J, Newman RA. Circadian infusion of floxuridine in patients with metastatic renal cell carcinoma. J Urol 146(3):709-13, 1991. PMID: 1831513.
- Dexeus FH, Logothetis CJ, Sella A, Fitz K, Striegel A, Amato RJ, Liu FJ. Serum biomarkers in metastatic renal cell carcinoma. Urology 38(1):6-10, 1991. PMID: 1714107.
- Sella A, Logothetis CJ, Dexeus FH, Amato R, Finn L, Fitz K. Cisplatin combination chemotherapy for elderly patients with urothelial tumours. Br J Urol 67(6):603-7, 1991. PMID: 2070205.
- Logothetis CJ, Hossan E, Sella A, Dexeus FH, Amato RJ. Fluorouracil and recombinant human interferon alfa-2a in the treatment of metastatic chemotherapy-refractory urothelial tumors. J Natl Cancer Inst 83(4):285-8, 1991. PMID: 1994058.
- Dexeus FH, Kilbourn R, Chong C, Logothetis CJ, Sella A, Grignon D. Association of germ cell tumors and Hodgkin's disease. Urology 37(2):129-34, 1991. PMID: 1846990.
- Sella A, Logothetis CJ, Dexeus FH, Amato R. Chemotherapy immediately after surgery for patients with germ cell tumors. Urology 36(3):264-6, 1990. PMID: 2168105.
- Gutterman J, Vadhan-Raj S, Logothetis C, Anaissle E, Estey E, Talpaz M, Kurzrock R. Effects of granulocyte-macrophage colony-stimulating factor in iatrogenic myelosuppression, bone marrow failure, and regulation of host defense. Semin Hematol 27(3):15-24, 1990. PMID: 2198660.
- Logothetis CJ, Dexeus FH, Finn L, Sella A, Amato RJ, Ayala AG, Kilbourn RG. A prospective randomized trial comparing MVAC and CISCA chemotherapy for patients with metastatic urothelial tumors. J Clin Oncol 8(6):1050-5, 1990. PMID: 2189954.
- Logothetis CJ, Dexeus FH, Sella A, Amato RJ, Kilbourn RG, Finn L, Gutterman JU. Escalated therapy for refractory urothelial tumors: methotrexate-vinblastine-doxorubicin-cisplatin plus unglycosylated recombinant human granulocyte-macrophage colony-stimulating factor. J Natl Cancer Inst 82(8):667-72, 1990. PMID: 2181151.
- Logothetis CJ. The case for relevant staging of germ cell tumors. Cancer 65(3):709-17, 1990. PMID: 2154316.
- Dexeus FH, Logothetis CJ, Sella A, Fitz K, Amato R, Reuben JM, Dozier N. Phase II study of coumarin and cimetidine in patients with metastatic renal cell carcinoma. J Clin Oncol 8(2):325-9, 1990. PMID: 2137163.
- Logothetis CJ, Dexeus FH, Chong C, Sella A, Ogden S. The impact of chemotherapy on the survival of patients with metastatic urothelial tumors. Prog Clin Biol Res 350:107-14, 1990. PMID: 2201037.
- Logothetis CJ, Chong C, Dexeus FH, Sella A, Ogden S. Intensive chemotherapy for metastatic nonseminomatous germ cell tumors. Prog Clin Biol Res 350:301-7, 1990. PMID: 1696741.
- Dexeus FH, Logothetis CJ, Sella A, Finn L. Interferon alternating with chemotherapy for patients with metastatic renal cell carcinoma. Am J Clin Oncol 12(4):350-4, 1989. PMID: 2667326.
- Sella A, Dexeus FH, Chong C, Ro JY, Logothetis CJ. Radiation therapy-associated invasive bladder tumors. Urology 33(3):185-8, 1989. PMID: 2919477.
- Tetu B, Ro JY, Ayala AG, Ordonez NG, Logothetis CJ, von Eschenbach AC. Small cell carcinoma of prostate associated with myasthenic (Eaton-Lambert) syndrome. Urology 33(2):148-52, 1989. PMID: 2536972.
- Logothetis CJ, Dexeus FH, Chong C, Sella A, Ayala AG, Ro JY, Pilat S. Cisplatin, cyclophosphamide and doxorubicin chemotherapy for unresectable urothelial tumors: the M.D. Anderson experience. J Urol 141(1):33-7, 1989. PMID: 2908950.
- Dexeus FH, Shirkhoda A, Logothetis CJ, Chong C, Sella A, Ogden S, Swanson D. Clinical and radiological correlation of retroperitoneal metastasis from nonseminomatous testicular cancer treated with chemotherapy. Eur J Cancer Clin Oncol 25(1):35-43, 1989. PMID: 2920767.
- Shirkhoda A, Dexeus FH, Logothetis CJ. Clinical and radiologic staging of locally advanced and inoperable bladder carcinoma. J Comput Tomogr 12(4):298-302, 1988. PMID: 3197433.
- Logothetis CJ, Johnson DE, Chong C, Dexeus FH, Sella A, Ogden S, Smith T, Swanson DA, Babaian RJ, Wishnow KI, et al. Adjuvant cyclophosphamide, doxorubicin, and cisplatin chemotherapy for bladder cancer: an update. J Clin Oncol 6(10):1590-6, 1988. PMID: 3171626.
- Dunphy CH, Ayala AG, Swanson DA, Ro JY, Logothetis C. Clinical stage I nonseminomatous and mixed germ cell tumors of the testis. A clinicopathologic study of 93 patients on a surveillance protocol after orchiectomy alone. Cancer 62(6):1202-6, 1988. PMID: 2842034.
- Chong CD, Logothetis CJ, Savaraj N, Fritsche HA, Gietner AM, Samuels ML. The correlation of vinblastine pharmacokinetics to toxicity in testicular cancer patients. J Clin Pharmacol 28(8):714-8, 1988. PMID: 3216038.
- Dexeus FH, Logothetis CJ, Chong C, Sella A, Ogden S. Genetic abnormalities in men with germ cell tumors. J Urol 140(1):80-4, 1988. PMID: 2837589.
- Logothetis CJ, Johnson DE, Chong C, Dexeus FH, Ogden S, von Eschenbach A, Ayala A. Adjuvant chemotherapy of bladder cancer: a preliminary report. J Urol 139(6):1207-11, 1988. PMID: 3373589.
- Chong CD, Logothetis CJ, von Eschenbach AC, Ayala AG, Samuels ML. Successful treatment of pure endodermal sinus tumors in adult men. J Clin Oncol 6(2):303-7, 1988. PMID: 2448426.
- Floyd C, Ayala AG, Logothetis CJ, Silva EG. Spermatocytic seminoma with associated sarcoma of the testis. Cancer 61(2):409-14, 1988. PMID: 3334976.
- Logothetis CJ, Samuels ML, Ogden SL, Dexeus FH, Chong CD. Cyclophosphamide and sequential cisplatin for advanced seminoma: long-term followup in 52 patients. J Urol 138(4):789-94, 1987. PMID: 3656535.
- Sella A, Logothetis CJ, Ro JY, Swanson DA, Samuels ML. Sarcomatoid renal cell carcinoma. A treatable entity. Cancer 60(6):1313-8, 1987. PMID: 2441841.
- Logothetis CJ, Swanson DA, Dexeus F, Chong C, Ogden S, Ayala AG, von Eschenbach AC, Johnson DE, Samuels ML. Primary chemotherapy for clinical stage II nonseminomatous germ cell tumors of the testis: a follow-up of 50 patients. J Clin Oncol 5(6):906-11, 1987. PMID: 2438389.
- Tetu B, Ro JY, Ayala AG, Johnson DE, Logothetis CJ, Ordonez NG. Small cell carcinoma of the prostate. Part I. A clinicopathologic study of 20 cases. Cancer 59(10):1803-9, 1987. PMID: 3030528.
- Dexeus FH, Logothetis CJ, Samuels ML, Ayala AG, Hossan E. Complete responses in metastatic transitional cell carcinoma of the prostate with cisplatin regimens. J Urol 137(1):122-5, 1987. PMID: 3795354.
- Chong C, Logothetis CJ, von Eschenbach A, Ayala A, Samuels M. Orchiectomy in advanced germ cell cancer following intensive chemotherapy: a comparison of systemic to testicular response. J Urol 136(6):1221-3, 1986. PMID: 3022018.
- Dexeus FH, Logothetis C, Samuels ML, Hossan B. Phase II study of spirogermanium in metastatic prostate cancer. Cancer Treat Rep 70(9):1129-30, 1986. PMID: 3742495.
- Logothetis CJ, Samuels ML, Selig DE, Ogden S, Dexeus F, Swanson D, Johnson D, von Eschenbach A. Cyclic chemotherapy with cyclophosphamide, doxorubicin, and cisplatin plus vinblastine and bleomycin in advanced germinal tumors. Results with 100 patients. Am J Med 81(2):219-28, 1986. PMID: 2426944.
- Dexeus F, Logothetis C, Hossan E, Samuels ML. Carcinoembryonic antigen and beta-human chorionic gonadotropin as serum markers for advanced urothelial malignancies. J Urol 136(2):403-7, 1986. PMID: 2426474.
- Logothetis CJ, Samuels ML, Selig DE, Johnson DE, Swanson DA, von Eschenbach AC. Primary chemotherapy followed by a selective retroperitoneal lymphadenectomy in the management of clinical stage II testicular carcinoma: a preliminary report. J Urol 134(6):1127-30, 1985. PMID: 2414470.
- Logothetis CJ, Samuels ML, Ogden S, Dexeus FH, Swanson D, Johnson DE, von Eschenbach A. Cyclophosphamide, doxorubicin and cisplatin chemotherapy for patients with locally advanced urothelial tumors with or without nodal metastases. J Urol 134(3):460-4, 1985. PMID: 2993671.
- Logothetis CJ, Samuels ML, Ogden S. Chemotherapy for adenocarcinomas of bladder and urachal origin: 5-fluorouracil, doxorubicin, and mitomycin-C. Urology 26(3):252-5, 1985. PMID: 3929441.
- Dexeus F, Logothetis CJ, Samuels ML, Hossan E, von Eschenbach AC. Continuous infusion of vinblastine for advanced hormone-refractory prostate cancer. Cancer Treat Rep 69(7-8):885-6, 1985. PMID: 4016795.
- Logothetis CJ, Samuels ML, Selig DE, Dexeus FH, Johnson DE, Swanson DA, von Eschenbach AC. Chemotherapy of extragonadal germ cell tumors. J Clin Oncol 3(3):316-25, 1985. PMID: 2579212.
- Logothetis CJ, Samuels ML, Selig D, Swanson D, Johnson DE, von Eschenbach AC. Improved survival with cyclic chemotherapy for nonseminomatous germ cell tumors of the testis. J Clin Oncol 3(3):326-35, 1985. PMID: 2579213.
- Logothetis CJ, Newell GR, Samuels ML. Testicular cancer in homosexual men with cellular immune deficiency: report of 2 cases. J Urol 133(3):484-6, 1985. PMID: 2579253.
- Logothetis CJ, Samuels ML, Selig DE, Wallace S, Johnson DE. Combined intravenous and intra-arterial cyclophosphamide, doxorubicin, and cisplatin (CISCA) in the management of select patients with invasive urothelial tumors. Cancer Treat Rep 69(1):33-8, 1985. PMID: 2981619.
- Logothetis CJ. Perioperative chemotherapy for the management of primary local regional urothelial tumors. Prog Clin Biol Res 201:359-66, 1985. PMID: 3841594.
- Logothetis CJ. Preoperative chemotherapy in the treatment of germinal tumors. Prog Clin Biol Res 201:341-50, 1985. PMID: 2419920.
- Rusch VW, Logothetis C, Samuels M. Endodermal sinus tumor of the mediastinum. Report of apparent cure in two patients with extensive disease. Chest 86(5):745-7, 1984. PMID: 6207993.
- Logothetis CJ, Samuels ML. Surgery in the management of stage III germinal cell tumors. Observations on the M.D. Anderson Hospital experience, 1971-1979. Cancer Treat Rev 11(1):27-37, 1984. PMID: 6203643.
- Logothetis CJ, Samuels ML, Trindade A, Grant C, Gomez L, Ayala A. The prognostic significance of endodermal sinus tumor histology among patients treated for stage III nonseminomatous germ cell tumors of the testes. Cancer 53(1):122-8, 1984. PMID: 6317156.
- Logothetis CJ, Samuels ML, von Eschenbach AC, Trindade A, Ogden S, Grant C, Johnson DE. Doxorubicin, mitomycin-C, and 5-fluorouracil (DMF) in the treatment of metastatic hormonal refractory adenocarcinoma of the prostate, with a note on the staging of metastatic prostate cancer. J Clin Oncol 1(6):368-79, 1983. PMID: 6422006.
- Libshitz HI, Jing BS, Wallace S, Logothetis CJ. Sterilized metastases: a diagnostic and therapeutic dilemma. AJR Am J Roentgenol 140(1):15-9, 1983. PMID: 6600307.
- Bracken RB, Johnson DE, Frazier OH, Logothetis CJ, Trindade A, Samuels ML. The role of surgery following chemotherapy in stage III germ cell neoplasms. J Urol 129(1):39-43, 1983. PMID: 6298475.
- Logothetis CJ, Samuels ML, Trindade A, Johnson DE. The growing teratoma syndrome. Cancer 50(8):1629-35, 1982. PMID: 6288220.
- Logothetis CJ, Samuels ML, Wallace S, Chuang V, Trindade A, Grant C, Haynie TP, 3rd, Johnson DE. Management of pelvic complications of malignant urothelial tumors with combined intra-arterial and iv chemotherapy. Cancer Treat Rep 66(7):1501-7, 1982. PMID: 7046931.
- Logothetis CJ, von Eschenbach AC, Samuels ML, Trindade A, Johnson DE. Doxorubicin, mitomycin, and 5-FU (DMF) in the treatment of hormone-resistant stage D prostate cancer: a preliminary report. Cancer Treat Rep 66(1):57-63, 1982. PMID: 7053267.
- Logothetis CJ, Samuels ML, Trindade A. The management of brain metastases in germ cell tumors. Cancer 49(1):12-8, 1982. PMID: 6274499.
- Trindade A, Samuels ML, Logothetis CJ. Chemotherapy of carcinoma of renal pelvis: preliminary report. Urology 18(1):54-9, 1981. PMID: 6894814.
Invited Articles
- Gillessen S, Omlin A, Attard G, de Bono JS, Efstathiou E, Fizazi K, Halabi S, Nelson PS, Sartor O, Smith MR, Soule HR, Akaza H, Beer TM, Beltran H, Chinnaiyan AM, Daugaard G, Davis ID, De Santis M, Drake CG, Eeles RA, Fanti S, Gleave ME, Heidenreich A, Hussain M, James ND, Lecouvet FE, Logothetis CJ, Mastris K, Nilsson S, Oh WK, Olmos D, Padhani AR, Parker C, Rubin MA, Schalken JA, Scher HI, Sella A, Shore ND, Small EJ, Sternberg CN, Suzuki H, Sweeney CJ, Tannock IF, Tombal B. Management of patients with advanced prostate cancer: recommendations of the St Gallen Advanced Prostate Cancer Consensus Conference (APCCC) 2015. Ann Oncol 26(8):1589-604, 2015. e-Pub 2015. PMID: 26041764.
- Sharma P, Logothetis C. Prostate cancer: Combination of vaccine plus ipilimumab-safety and toxicity. Nat Rev Urol 9(6):302-3. e-Pub 2012. PMID: 22565371.
- Logothetis CJ, Efstathiou E, Manuguid F, Kirkpatrick P. Abiraterone acetate. Nat Rev Drug Discov 10(8):573-4, 2011. e-Pub 2011. PMID: 21804589.
- Logothetis CJ. When 'dueling technologies' are mistaken for progress. BJU Int 107(11):1699-700, 2011. PMID: 21592278.
- Efstathiou E, Logothetis CJ. Prostate cancer: Thalidomide for prostate cancer: is there progress?. Nat Rev Urol 6(5):248-50, 2009. PMID: 19424170.
- Millikan RE, Wen S, Pagliaro LC, Brown MA, Moomey B, Do KA, Logothetis CJ. Phase III trial of androgen ablation with or without three cycles of systemic chemotherapy for advanced prostate cancer. J Clin Oncol 26(36):5936-42, 2008. e-Pub 2008. PMID: 19029421.
- Efstathiou E, Logothetis CJ. Review of late complications of treatment and late relapse in testicular cancer. J Natl Compr Canc Netw 4(10):1059-70, 2006. PMID: 17112453.
- Motzer RJ, Bolger GB, Boston B, Carducci MA, Fishman M, Hancock SL, Hauke RJ, Hudes GR, Jonasch E, Kantoff P, Kuzel TM, Lange PH, Levine EG, Logothetis C, Margolin KA, Pohar K, Redman BG, Robertson CN, Samlowski WE, Sheinfeld J; National Comprehensive Cancer Network. Kidney cancer. Clinical practice guidelines in oncology. J Natl Compr Canc Netw 4(10):1072-81, 2006. PMID: 17112454.
- Logothetis CJ, Lin SH. Osteoblasts in prostate cancer metastasis to bone. Nat Rev Cancer 5(1):21-8, 2005. PMID: 15630412.
- Logothetis CJ. The case for a biologically based classification of prostate cancer. Semin Oncol 30(5):562-6, 2003. PMID: 14571406.
- Tu SM, Lin SH, Logothetis CJ. Stem-cell origin of metastasis and heterogeneity in solid tumours. Lancet Oncol 3(8):508-13, 2002. PMID: 12147437.
- Logothetis C, Millikan R. Docetaxel in the management of advanced or metastatic urothelial tract cancer. Oncology (Williston Park) 16(6 Suppl 6):107-11, 2002. PMID: 12108893.
- Logothetis CJ. A Framework for Rational and Accelerated Development of Therapy for Prostate Cancer. Principles and Practice of Oncology 16(6), 2002.
- Merritt JA, Roth JA, Logothetis CJ. Clinical evaluation of adenoviral-mediated p53 gene transfer: review of INGN 201 studies. Semin Oncol 28(5 Suppl 16):105-14, 2001. PMID: 11706402.
- Logothetis CJ. Docetaxel in the Treatment of Prostate Cancer: Opportunities for Combination Regimens and Challenges to Development. . Seminars in Oncology 28(4):Supplement N, 2001.
- Bahnson RR, Hanks GE, Huben RP, Kantoff P, Kozlowski JM, Kuettel M, Lange PH, Logothetis C, Pow-Sang JM, Roach M, 3rd, Sandler H, Scardino PT, Taylor RJ, Urban DA, Walsh PC, Wilson TG. NCCN Practice Guidelines for Prostate Cancer. Oncology (Williston Park) 14(11A):111-9, 2000. PMID: 11195405.
- Kim J, Logothetis CJ. Serologic tumor markers, clinical biology, and therapy of prostatic carcinoma. Urol Clin North Am 26(2):281-90, 1999. PMID: 10361551.
- Navone NM, Logothetis CJ, von Eschenbach AC, Troncoso P. Model systems of prostate cancer: uses and limitations. Cancer Metastasis Rev 17(4):361-71, 1998. PMID: 10453280.
- Gjertsen BT, Logothetis CJ, McDonnell TJ. Molecular regulation of cell death and therapeutic strategies for cell death induction in prostate carcinoma. Cancer Metastasis Rev 17(4):345-51, 1998. PMID: 10453278.
- Corral DA, Logothetis CJ. New approaches in the treatment of metastatic transitional-cell cancer of the bladder. World J Urol 15(2):139-43, 1997. PMID: 9144905.
- Baker LH, Hanks G, Gershenson D, Kantoff P, Lange P, Logothetis C, Sandler H, Walsh P. NCCN Prostate Cancer Practice Guidelines. The National Comprehensive Cancer Network. Oncology (Williston Park) 10(11 Suppl):265-88, 1996. PMID: 8953609.
- Tu, S, Jones D, Finn L, Amato R, Ellerhorst J, Kilbourn R, Logothetis CJ. Strontium-89 (Str-89) combined with adriamycin (Adr) in the treatment of patients (pts) with androgen-independent prostate carcinoma (AI PCa), 1995.
- Logothetis CJ. Chemotherapeutic approaches in advanced prostate cancer. Oncology (Supplement) 8(11):15-18, 1994.
- Logothetis CJ, Amato RJ. Management of Residual Mass Following Effective Therapy for Seminoma, 1993.
- Logothetis C. Treatment of chemotherapy-refractory metastatic urothelial tumors. Urol Clin North Am 19(4):775-7, 1992. PMID: 1441031.
- Logothetis C, Hoosein N. The inhibition of the paracrine progression of prostate cancer as an approach to early therapy of prostatic carcinoma. J Cell Biochem Suppl 16H:128-34, 1992. PMID: 1337763.
- Logothetis CJ. The role of chemotherapy in the management of urothelial tumors: Interpretation of the M. D. Anderson Cancer Center results. World Journal of Urology 6(3):163-166, 1988.
- Logothetis CJ. Choriocarcinoma syndrome. Cancer Bulletin 36(2):118-120, 1984.
- Logothetis CJ, Samuels M. Intra-arterial chemotherapy for malignant urothelial tumors. Cancer Bulletin 36(1):47-52, 1984.
- Logothetis CJ. The lymphoma that wasn’t. World Journal of Urology 2:73-75, 1984.
- Logothetis, CJ, von Eschenbach A, Samuels ML, Trindade A, Johnson DE. DMF regimen for hormone-refractory adenocarcinoma of the prostate - The first 42 patients. Cancer Bulletin 34(1):26-28, 1982.
- Logothetis CJ. CISCA Chemotherapy for bladder cancer. Cancer Bulletin 33(2):79-80, 1981.
Editorials
- Logothetis CJ, Aparicio A, Koinis F, Corn PG, Efstathiou E. Prostate Cancer: Quo Vadis?. Eur Urol 76(6):709-711, 2019. PMID: 31300238.
- Logothetis CJ. Prostate cancer bone metastases: not so systemic after all. Lancet Oncol 15(7):675-6, 2014. PMID: 24836275.
- Logothetis CJ. Treatment of castrate-resistant prostate cancer. J Urol 190(2):439-40, 2013. PMID: 23707438.
- Logothetis CJ. Re: intratumor heterogeneity and branched evolution revealed by multiregion sequencing. Eur Urol 64(1):170, 2013. PMID: 23746321.
- Logothetis CJ. Treatment of prostate cancer metastases: more than semantics. Lancet 379(9810):4-6, 2012. PMID: 22093188.
- Kim J, Amos CI, Logothetis C. 5α-Reductase inhibitors for prostate-cancer prevention. N Engl J Med 365(24):2340, 2011. PMID: 22168662.
- Aparicio A, Logothetis CJ, Maity SN. Understanding the lethal variant of prostate cancer: power of examining extremes. Cancer Discov 1(6):466-8, 2011. PMID: 22586648.
- Logothetis CJ, Siefker-Radtke A. Words of wisdom. Re: final results of sequential doxorubicin plus gemcitabine and ifosfamide, paclitaxel, and cisplatin chemotherapy in patients with metastatic or locally advanced transitional cell carcinoma of the urothelium. Eur Urol 57(4):728-9, 2010. PMID: 20965043.
- Efstathiou E, Kim J, Logothetis CJ. Informative clinical investigation: a demanding taskmaster. J Clin Oncol 27(30):4937-8, 2009. PMID: 19720892.
- Logothetis CJ, Millikan R. Chemotherapy for advanced prostate cancer: 25 years later. J Clin Oncol 26(15):2423-4, 2008. PMID: 18487561.
- Logothetis CJ, Schellhammer PF. High-grade prostate cancer and the prostate cancer prevention trial. Cancer Prev Res (Phila Pa) 1(3):151-2, 2008. PMID: 19138948.
- Fizazi K, Chen I, Logothetis CJ. Germ-cell tumor survivors: the price for cure. Ann Oncol 13(2):187-9, 2002. PMID: 11885993.
Abstracts
- Sumit Kumar Subudhi, Ana Aparicio, Patricia Troncoso, Jianhua Zhang, Curtis Gumbs, Chang-jiun Wu, Jianjun Gao, Luis M Vence, Jorge M Blando, Paul Gettys Corn, John C. Araujo, Amado J. Zurita, Ina N. Prokhorova, Michael Van Alstine, Christopher Logothetis, Andrew Futreal, James Patrick Allison, Padmanee Sharma. Linking tumor mutational load to clinical responses to ipilimumab (IPI) in men with advanced prostate cancer (PCa). ASCO, 2017.
- Jianjun Gao, John Francis Ward, Curtis Alvin Pettaway, Lewis Z Shi, Sumit Kumar Subudhi, Luis M Vence, Hao Zhao, Jianfeng Chen, Hong Chen, Eleni Efstathiou, Patricia Troncoso, James Patrick Allison, Christopher Logothetis, Ignacio Ivan Wistuba, Jennifer Ann Wargo, Jorge M Blando, Manuel A Sepulveda, Jing Jing Sun, Padmanee Sharma. Investigation of mechanisms of resistance to ipilimumab therapy with a pre-surgical trial in patients with high-risk, localized prostate cancer. ASCO, 2017.
- Ana Aparicio, Lianchun Xiao, Elsa Li Ning Tapia, Anh Hoang, Naveen Ramesh, Wenhui Wu, Haidee Chancoco, Elisabeth I. Heath, Eleni Efstathiou, Timothy C. Thompson, Patricia Troncoso, Bradley McIntosh Broom, Amado J. Zurita, Nicholas Navin, Christopher Logothetis, Paul Gettys Corn. The aggressive variant prostate carcinoma (AVPC) molecular signature (-MS) and platinum-sensitivity in castration resistant prostate cancer (CRPC). ASCO, 2017.
- Celestia S. Higano, Shawn H. Zimberg, Sabina Dizdarevic, Lauren Christine Harshman, John Logue, Sergio Baldari, Timothy Richardson, David M. Bottomley, Martin Schostak, Bertrand F. Tombal, Juan Pablo Sade, Kurt Miller, Christopher Logothetis, Joaquim Bellmunt, Matthew Raymond Smith, Fred Saad, Renate Muenz-Wollny, Yoriko De Sanctis, A. Oliver Sartor, Cora N. Sternberg. Patient (pt) characteristics and treatment patterns in the radium (Ra)-223 REASSURE observational study. ASCO, 2017.
- Efstathiou E, Tsikkinis A, Wen S, Li Ning Tapia E, Hoang A, Aparicio A, Tu S-M, Rangel G, Troncoso P, Corn P, Araujo J, Logothetis C. Abiraterone acetate (AA) followed by randomization to dasatinib (D) or sunitinib malate (S) in metastatic castrate resistant prostate cancer (mCRPC). ESMO, 2016.
- Paul Gettys Corn, Elsa Li Ning Tapia, Lianchun Xiao, Elisabeth I. Heath, Haidee Chancoco, Anh Hoang, Eleni Efstathiou, Timothy C. Thompson, Patricia Troncoso, Christopher Logothetis, Ana Aparicio. Confirmatory analysis to determine associations between platinum-sensitivity, molecular signature of combined tumor suppressor defects and aggressive variant prostate carcinomas (AVPC). ASCO, 2016.
- Spyridon P Basourakos, John W. Davis, Brian Francis Chapin, John Francis Ward, Curtis Alvin Pettaway, Louis L. Pisters, Mary F. Achim, Xuemei Wang, Seungtaek Choi, Deborah A. Kuban, Patricia Troncoso, Christopher Logothetis, Timothy C. Thompson, Jeri Kim. Plasma caveolin-1 to predict disease reclassification in men with early stage prostate cancer in active surveillance. ASCO, 2016.
- Sumit Kumar Subudhi, Ana Aparicio, Patricia Troncoso, Jianhua Zhang, Curtis Gumbs, Chang-jiun Wu, Luis M Vence, Christopher Logothetis, Andrew Futreal, James Patrick Allison, Padmanee Sharma. A feasibility study to determine T cell responses to neoantigens following treatment with ipilimumab in men with metastatic castration-resistant prostate carcinoma (mCRPC). ASCO, 2016.
- Amado J. Zurita, Anders Carlsson, Madelyn S. Luttgen, Kelly Bethel, Patricia Troncoso, Paul Gettys Corn, Anand Kolatkar, James B Hicks, Christopher Logothetis, Peter Kuhn. A clinically applicable strategy to concurrently profile prostate cancer (PCa) in circulation and bone using high-definition single cell analysis (HD-SCA). ASCO, 2016.
- Eleni Efstathiou, John W. Davis, Mark Anton Titus, Brian Francis Chapin, Amado J. Zurita, Sijin Wen, Elsa M. Li Ning Tapia, Anh Hoang, Paul Gettys Corn, Xuemei Wang, Francine Whittington, Patricia Troncoso, Christopher Logothetis. Neoadjuvant enzalutamide (ENZA) and abiraterone acetate (AA) plus leuprolide acetate (LHRHa) versus AA+ LHRHa in localized high-risk prostate cancer (LHRPC). ASCO, 2016.
- Karim Fizazi, Aude Flechon, Gwenael / Le Teuff, Jozef Mardiak, Lance C. Pagliaro, Lionnel Geoffrois, Pierre Kerbrat, Christine Chevreau, Remy Delva, Frederic Rolland, Christine Theodore, Guilhem Roubaud, Gwenaelle Gravis, Jean-Christophe Eymard, Jean-pierre Malhaire, Claude Linassier, Muriel Habibian, Maria Reckova, Christopher Logothetis, Stephane Culine. Mature results of the GETUG 13 phase III trial in poor-prognosis germ-cell tumors (GCT). ASCO, 2016.
- Ana Aparicio, Li Shen, Elsa Li Ning Tapia, Jing-Fang Lu, Hsiang-Chun Chen, Jiexin Zhang, Guanglin Wu, Xuemei Wang, Patricia Troncoso, Paul Gettys Corn, Timothy C. Thompson, Bradley McIntosh Broom, Keith A. Baggerly, Christopher Logothetis, Sankar N. Maity. Molecular characterization of clinically defined aggressive variant prostate cancer (AVPCa) in prospectively collected tissues and corresponding patient derived xenografts (PDX). ASCO, 2015.
- Eleni Efstathiou, Patricia Troncoso, Elsa Li Ning Tapia, John W. Davis, Mark Anton Titus, Anh Hoang, Ina N. Prokhorova, Sijin Wen, Christopher Logothetis. Effects of preoperative abiraterone acetate (AA) plus enzalutamide (E) and leuprolide acetate (LHRHa) versus AA and LHRHa in localized high-risk prostate cancer (LHRPC). ASCO, 2015.
- Paul Gettys Corn, Shi-Ming Tu, Amado J. Zurita, Sumit Kumar Subudhi, John C. Araujo, Jeri Kim, Eric Jonasch, Lance C. Pagliaro, Arlene O. Siefker-Radtke, Jennifer Wang, Xuemei Wang, Elisabeth I. Heath, Christopher Logothetis, Ana Aparicio. A multi-institutional randomized phase II study (NCT01505868) of cabazitaxel (CAB) plus or minus carboplatin (CARB) in men with metastatic castration-resistant prostate cancer (mCRPC). ASCO, 2015.
- Brian Francis Chapin, Sean Eric Mcguire, Xuemei Wang, Patricia Troncoso, John W. Davis, Neema Navai, Sumit Kumar Subudhi, Amado J. Zurita, John C. Araujo, Curtis Alvin Pettaway, Surena F. Matin, Louis L. Pisters, John Francis Ward, Shi-Ming Tu, Jennifer Wang, Ott Le, Christopher Logothetis, Ana Aparicio. A prospective, multicenter, randomized phase II trial of best systemic therapy (BST) or BST plus definitive treatment (Surgery or Radiation) of the primary tumor in metastatic prostate cancer. ASCO, 2015.
- Eleni Efstathiou, Weimin Li, Michael Gormley, Ryan McMullin, Deborah Sokol Ricci, John W. Davis, Elsa M. Li Ning Tapia, Patricia Troncoso, Mark Anton Titus, Anh Hoang, Sijin Wen, Amado J. Zurita, Namphuong Tran, Weimin Peng, Thian Kheoh, Arturo Molina, Christopher Logothetis. Biological heterogeneity in localized high-risk prostate cancer (LHRPC) from a study of neoadjuvant abiraterone acetate plus leuprolide acetate (LHRHa) versus LHRHa. ASCO, 2015.
- Sankar N. Maity, Guanglin Wu, Jing-Fang Lu, Anh Hoang, Yosef Landesman, Dilara McCauley, Robert Carlson, Tami Rashal, Sharon Shacham, Bradley McIntosh Broom, Keith A. Baggerly, Ana Aparicio, Eleni Efstathiou, John C. Araujo, Christopher Logothetis. Effect of selinexor (KPT-330), a novel oral selective inhibitor of nuclear export (SINE), on tumor suppressors and cell cycle proteins in prostate cancer cells and regression of castration-resistant patient-derived xenograft tumor growth. Genitourinary Cancers Symposium, 2015.
- Ana Aparicio, Li Shen, Elsa Li Ning Tapia, Jing-Fang Lu, Hsiang-Chun Chen, Jiexin Zhang, Guanglin Wu, Xuemei Wang, Patricia Troncoso, Bradley McIntosh Broom, Keith A. Baggerly, Christopher Logothetis, Sankar N. Maity. A comprehensive molecular characterization of aggressive variant prostate cancer (PC). Genitourinary Cancers Symposium, 2015.
- Charles J. Ryan, Matthew Raymond Smith, Karim Fizazi, Fred Saad, Cora N. Sternberg, Christopher Logothetis, Eric Jay Small, Joan Carles, Thomas W. Flaig, Mary-Ellen Taplin, Celestia S. Higano, Paul L. De Souza, Johann Sebastian De Bono, Thomas W. Griffin, Peter De Porre, Youn Choi Park, Jinhui Li, Thian San Kheoh, Arturo Molina, Dana E. Rathkopf. Impact of crossover and baseline prognostic factors on overall survival (OS) with abiraterone acetate (AA) in the COU-AA-302 final analysis. Genitourinary Cancers Symposium, 2015.
- Efstathiou E, Li Ning Tapia E, Aparicio A, Tu SM, Wen S, Hoang A, Pagliaro L, Harmon C, Troncoso P, Araujo JC, Logothetis C. Maximal Androgen Depletion with Abiraterone Acetate (AA) Followed By Randomization of Maximal Androgen Ablation With Molecular Targeted Therapies Dasatinib or Sunitinib Malate in Metastatic Castrate Resistant Prostate Cancer (MCRPC). Report on Candidate Predictive Androgen Signaling Signature. ESMO, 2014.
- Fizazi K, Drake CJ, Kwon ED, Bossi A, van den Eertwegh AJ, Scher HI, Beer TM, McHenry MB, Liu D, Gerritsen WR, Logothetis C. Updated Overall Survival (OS) From the Phase 3 Trial, CA184-043: Ipilimumab (IPI) vs Placebo (PBO) in Patients With Post-Docetaxel Metastatic Castration-Resistant Prostate Cancer (MCRPC). ESMO, 2014.
- Shore, Neal (Myrtle Beach, SC); Rathkopf, Dana; Smith, Matthew R.; de Bono, Johann S.; Logothetis, Christopher; de Souza, Paul; Fizazi, Karim; Mulders, Peter F.A.; Mainwaring, Paul; Hainsworth, John D.; Beer, Tomasz M.; North, Scott; Fradet, Yves; Griffin, Thomas; Park, Youn C.; Kheoh, Thian; Small, Eric J.; Scher, Howard I.; Molina, Arturo; Ryan, Charles J.. Efficacy and Long-term Safety Analysis of Study COU-AA-302: Abiraterone Acetate Plus Prednisone in Chemotherapy-naïve Metastatic Castration-resistant Prostate Cancer. AUA, 2014.
- Sankar Narayan Maity, Guanglin Wu, Jing-Fang Lu, Anh Hoang, Yosef Landesman, Dilara McCauley, Sharon Shacham, Michael G. Kauffman, Ana M. Aparicio, Eleni Efstathiou, John C. Araujo, Christopher J. Logothetis. Preclinical efficacy of the novel, oral Selective Inhibitor of Nuclear Export (SINE) Selinexor (KPT-330) on castration resistant prostate cancer. AACR, 2014.
- Jian Gu, Yonggang He, Sara S. Strom, Christopher J. Logothetis, Jeri Kim, Xifeng Wu. A genetic variant near KLK3 gene is associated with aggressive prostate cancer and can stratify Gleason score 7 patients. AACR, 2014.
- Eleonora Dondossola, Stephanie Alexander, Steve Alexander, Boris M. Holzapfel, Christopher J. Logothetis, Dietmar W. Hutmacher, Peter Fried. A humanized bone model for preclinical monitoring of prostate cancer lesions by intravital multiphoton microscopy. AACR, 2014.
- Eleni Efstathiou, Mark Anton Titus, Sijin Wen, Aileen SanMiguel, Anh Hoang, Angela De Haas-Amatsaleh, Frank Perabo, De Phung, Patricia Troncoso, Taoufik Ouatas, Christopher Logothetis. Enzalutamide (ENZA) in combination with abiraterone acetate (AA) in bone metastatic castration resistant prostate cancer (mCRPC). ASCO, 2014.
- Deborah Sokol Ricci, Weimin Li, Thomas W. Griffin, Michael Gormley, Erin Henitz, Charles J. Ryan, Johann Sebastian De Bono, Gerhardt Attard, Alfons JM van den Eertwegh, Dirk L. Schrijvers, John J. Gullo, Henrik Suttmann, Joan Carles, Jose Maria Piulats Rodriguez, Robert J. Jones, Christopher Logothetis, Dana E. Rathkopf, Howard I. Scher, Eleni Efstathiou. Predicting response to abiraterone acetate (AA): mRNA biomarker analysis of study COU-AA-302. ASCO, 2014.
- Mehmet Asim Bilen, Kenneth R. Hess, Ana Aparicio, Jeri Kim, Amado J. Zurita, Lance C. Pagliaro, John C. Araujo, Paul Gettys Corn, Bradley J. Atkinson, Nizar M. Tannir, Padmanee Sharma, Sue-Hwa Lin, Christopher Logothetis, Shi-Ming Tu. Sipuleucel-T cellular immunotherapy: Clinical predictors of survival in patients with castration-resistant prostate cancer (CRPC). ASCO, 2014.
- Shi-Ming Tu, Mehmet Asim Bilen, Zachary H. Tu, Raphael General, John Francis Ward, Louis L. Pisters, Rosale General, Adrienne H. Chen, Yago Nieto, Lance C. Pagliaro, S. J. Yeung, Christopher Logothetis, Sue-Hwa Lin, Ivan Gorlov. Nonseminomatous germ cell tumor of the testis: Prognostic factors for a lethal phenotype. Genitourinary Cancers Symposium, 2014.
- Yohann Loriot, Lance C. Pagliaro, Aude Flechon, Jozef Mardiak, Lionnel Geoffrois, Pierre Kerbrat, Christine Chevreau, Remy Delva, Frederic Rolland, Christine Theodore, Binh Bui, Gwenaelle Gravis, Jean-Christophe Eymard, Jean-pierre Malhaire, Claude Linassier, Muriel Habibian, Christopher Logothetis, Stephane Culine, Agnes Laplanche, Karim Fizazi. Patterns of relapse in poor-prognosis germ cell tumors in the GETUG 13 trial: Implications for assessment of brain progression. Genitourinary Cancers Symposium, 2014.
- Paul Gettys Corn, Shi-Ming Tu, Amado J. Zurita, John C. Araujo, Lance C. Pagliaro, Christopher Logothetis, Ana Aparicio. A randomized phase I/II study to examine the contribution of carboplatin to cabazitaxel for the treatment of men with metastatic castration-resistant prostate cancer (mCRPC) with and without anaplastic features. Genitourinary Cancers Symposium, 2014.
- Evan Y. Yu, Fred Saad, Anil Londhe, Neal D. Shore, Hendrik Van Poppel, Dana E. Rathkopf, Matthew R. Smith, Christopher Logothetis, Paul L. De Souza, Karim Fizazi, Peter F.A. Mulders, Paul N. Mainwaring, John D. Hainsworth, Tomasz M. Beer, Scott A. North, Eric Jay Small, Howard I. Scher, Thomas W. Griffin, Margaret K. Yu, Charles J. Ryan. Association of alkaline phosphatase (ALP) with clinical outcomes in chemotherapy-naive patients (pts) with metastatic castration-resistant prostate cancer (mCRPC): Results from COU-AA-302. Genitourinary Cancers Symposium, 2014.
- Patricia A. Parker, John W. Davis, David Latini, George Baum, Xuemei Wang, John Francis Ward, Deborah A. Kuban, Steven J. Frank, Andrew Lee, Christopher Logothetis, Jeri Kim. Associations between uncertainty, anxiety, and quality of life in men with favorable-risk prostate cancer on active surveillance: Two-and-a-half years' follow-up. Genitourinary Cancers Symposium, 2014.
- Tomasz M. Beer, Christopher Logothetis, Winald R. Gerritsen, Eugene D. Kwon, Howard I. Scher, Alberto Bossi, Alfons JM van den Eertwegh, Charles G. Drake, Brent McHenry, David Liu, Karim Fizazi. Characterization of immune-related adverse events (irAEs) in a phase 3 trial of ipilimumab (Ipi) versus placebo (Pbo) in post-docetaxel mCRPC. Genitourinary Cancers Symposium, 2014.
- Charles G. Drake, Eugene D. Kwon, Karim Fizazi, Alberto Bossi, Alfons JM van den Eertwegh, Christopher Logothetis, Howard I. Scher, Tomasz M. Beer, Brent McHenry, David Liu, Winald R. Gerritsen. Results of subset analyses on overall survival (OS) from study CA184-043: Ipilimumab (Ipi) versus placebo (Pbo) in post-docetaxel metastatic castration-resistant prostate cancer (mCRPC). Genitourinary Cancers Symposium, 2014.
- William R. Moore, Sankar N. Maity, Joel Robert Eisner, Edward P. Garvey, William J. Hoekstra, Mark Anton Titus, Christopher Logothetis, John C. Araujo, Eleni Efstathiou, Robert J. Schotzinger. The enzymology of the selective CYP17 lyase inhibitor, VT-464, and its effects in castration-resistant prostate cancer (CRPC) models. Genitourinary Cancers Symposium, 2014.
- Zurita AJ, Carlsson A, Luttgen MS, Bethel K, Logothetis CJ, Hicks J, Kuhn P,. High-Definition Single Cell Analysis (HD-SCA) of Prostate Cancer (PCa) Cells in Matched Bone Marrow and Blood from Patients. ESMO, 2014.
- Subudhi SK, Aparicio A, Zurita AJ, Araujo JC, Corn PG, Tu SM, Wang X, Harris DR, Winslow KA, Gao J, Logothetis CJ, Sharma P. Finite androgen deprivation therapy (ADT) plus ipilimumab (IPI) in men with hormon-naive metastatic prostate cancer (HN-MPCa). ESMO, 2014.
- Mehmet Asim Bilen, Sue-Hwa Lin, Rosale General, Lance C. Pagliaro, Christopher Logothetis, Ivan Gorlov, Shi-Ming Tu; Baylor College of Medicine, Houston, TX; The University of Texas MD Anderson Cancer Center, Houston, TX. Prediction of a potential lethal phenotype in testicular nonseminomatous germ cell tumor. ASCO, 2013.
- Farshid Dayyani, Graciela M. Nogueras-Gonzalez, Rebecca Slack, Randall E. Millikan, Amado J. Zurita, John C. Araujo, Gary E. Gallick, Christopher Logothetis, Paul Gettys Corn; The University of Texas MD Anderson Cancer Center, Houston, TX; Essentia Health Cancer Center (Duluth), Duluth, MN. Serum insulin to predict time to castration-resistant progression and overall survival in metastatic androgen-dependent prostate cancer (mADPCa). ASCO, 2013.
- Amado J. Zurita, Farideh Z. Bischoff, Ivan Gorlov, Julie Ann Mayer, Tony J. Pircher, Steve Mikolajczyk, Christopher Logothetis, Sue-Hwa Lin; The University of Texas MD Anderson Cancer Center, Houston, TX; Biocept Inc., San Diego, CA. Cadherin-11 (Cad11) for detection of epithelial-mesenchymal transition (EMT) in circulating prostate cancer (PCa) cells. ASCO, 2013.
- Tomasz M. Beer, Christopher Logothetis, Padmanee Sharma, Yohann Loriot, Karim Fizazi, Alberto Bossi, Eugene D. Kwon, Brent McHenry, Paul Gagnier, Winald R. Gerritsen; Oregon Health & Science University Knight Cancer Institute, Portland, OR; The University of Texas MD Anderson Cancer Center, Houston, TX; Institut Gustave Roussy, Villejuif, France; Mayo Clinic, Rochester, MN; Bristol-Myers Squibb, Wallingford, CT; Radboud University Nijmegen Medical Centre, Nijmegen, Netherlands. CA184-095: A randomized, double-blind, phase III trial to compare the efficacy of ipilimumab (Ipi) versus placebo in asymptomatic or minimally symptomatic patients (pts) with metastatic chemotherapy-naive castration-resistant prostate cancer (CRPC). ASCO, 2013.
- Jeri Kim, John Francis Ward, Curtis A. Pettaway, Xuemei Wang, Deborah A. Kuban, Steven J. Frank, Andrew Lee, Louis L. Pisters, Surena F. Matin, Jay Bakul Shah, Jose A. Karam, Brian Francis Chapin, John N. Papadopoulos, Mary F. Achim, Karen Elizabeth Hoffman, Thomas J. Pugh, Seungtaek Choi, Christopher Logothetis, Patricia Troncoso, John W. Davis; The University of Texas MD Anderson Cancer Center, Houston, TX. Risk of missing advanced stage or high grade tumors during active surveillance (AS) even in favorable-risk prostate cancer (PC). ASCO, 2013.
- Howard I. Scher, Matthew R. Smith, Christopher Sweeney, Paul Gettys Corn, Christopher Logothetis, Nicholas J. Vogelzang, David C. Smith, Maha Hussain, Daniel J. George, Johann Sebastian De Bono, Celestia S. Higano, Eric Jay Small, Jonathan Goldin, Matthew S. Brown, Dana T. Aftab, Mojtaba Noursalehi, Aaron Weitzman, Ethan M. Basch; Memorial Sloan-Kettering Cancer Center, New York, NY; Massachusetts General Hospital Cancer Center, Boston, MA; Dana-Farber Cancer Institute, Boston, MA; The University of Texas MD Anderson Cancer Center, Houston, TX; Comprehensive Cancer Centers of Nevada, The US Oncology Network, Las Vegas, NV; University of Michigan Comprehensive Cancer Center, Ann Arbor, MI; Duke Cancer Institute, Durham, NC; The Institute of Cancer Research, The Royal Marsden NHS Foundation Trust, Sutton, United Kingdom; Fred Hutchinson Cancer Research Center, Seattle, WA; University of California, San Francisco, San Francisco, CA; University of California, Los Angeles, Los Angeles, CA; Center for Computer Vision and Imaging Biomarkers, University of California, Los Angeles, CA; Exelixis, Inc, South San Francisco, CA. An exploratory analysis of bone scan lesion area (BSLA), circulating tumor cell (CTC) change, pain reduction, and overall survival (OS) in patients (pts) with castration-resistant prostate cancer (CRPC) treated with cabozantinib (cabo): Updated results of a phase II nonrandomized expansion (NRE) cohort. ASCO, 2013.
- Charles J. Ryan, Anil Londhe, Arturo Molina, Matthew R. Smith, Johann Sebastian De Bono, Peter Mulders, Dana E. Rathkopf, Fred Saad, Christopher Logothetis, Karim Fizazi, Howard I. Scher, Eric Jay Small, Shannon Matheny, Thian San Kheoh, Thomas W. Griffin; Helen Diller Family Comprehensive Cancer Center, University of California-San Francisco, San Francisco, CA; Janssen Research & Development, LLC, Raritan, NJ; Janssen Research & Development, LLC, Los Angeles, CA; Massachusetts General Hospital Cancer Center, Boston, MA; The Institute of Cancer Research, The Royal Marsden NHS Foundation Trust, Sutton, United Kingdom; Radboud University Medical Centre, Nijmegen, Netherlands; Memorial Sloan-Kettering Cancer Center, New York, NY; University of Montreal, Montreal, QC, Canada; The University of Texas MD Anderson Cancer Center, Houston, TX; Institut Gustave Roussy, University of Paris Sud, Villejuif, France. Relationship of baseline PSA and degree of PSA decline to radiographic progression-free survival (rPFS) in patients with chemotherapy-naive metastatic castration-resistant prostate cancer (mCRPC): Results from COU-AA-302. ASCO, 2013.
- Dana E. Rathkopf, Matthew R. Smith, Johann Sebastian De Bono, Christopher Logothetis, Neal Shore, Paul L. De Souza, Karim Fizazi, Peter Mulders, Paul N. Mainwaring, John D Hainsworth, Tomasz M. Beer, Scott A. North, Yves Fradet, Thomas W. Griffin, Youn Choi Park, Thian San Kheoh, Eric Jay Small, Howard I. Scher, Arturo Molina, Charles J. Ryan; Memorial Sloan-Kettering Cancer Center, New York, NY; Massachusetts General Hospital Cancer Center, Boston, MA; The Institute of Cancer Research, The Royal Marsden NHS Foundation Trust, Sutton, United Kingdom; The University of Texas MD Anderson Cancer Center, Houston, TX; Carolina Urologic Research Center, Myrtle Beach, SC; University of Western Sydney School of Medicine, Ingham Institute, Liverpool, Australia; Institut Gustave Roussy, University of Paris Sud, Villejuif, France; Radboud University Medical Centre, Nijmegen, Netherlands; Haematology and Oncology Clinics of Australia, Brisbane, Australia; Sarah Cannon Research Institute, Nashville, TN; Oregon Health & Science University Knight Cancer Institute, Portland, OR; Cross Cancer Institute, Edmonton, AB, Canada; Laval University, Québec, QC, Canada; Janssen Research & Development, LLC, Los Angeles, CA; Janssen Research & Development, LLC, Raritan, NJ; Helen Diller Family Comprehensive Cancer Center, University of California-San Francisco, San Francisco, CA. Long-term safety and efficacy analysis of abiraterone acetate (AA) plus prednisone (P) in metastatic castration-resistant prostate cancer (mCRPC) without prior chemotherapy (COU-AA-302). ASCO, 2013.
- Karim Fizazi, Lance C. Pagliaro, Aude Flechon, Jozef Mardiak, Lionnel Geoffrois, Pierre Kerbrat, Christine Chevreau, Remy Delva, Frederic Rolland, Christine Theodore, Guilhem Roubaud, Gwenaelle Gravis, Jean-Christophe Eymard, Jean-pierre Malhaire, Claude Linassier, Muriel Habibian, Florence Journeau, Christopher Logothetis, Stephane Culine, Agnes Laplanche. A phase III trial of personalized chemotherapy based on serum tumor marker decline in poor-prognosis germ-cell tumors: Results of GETUG 13. ASCO, 2013.
- Farshid Dayyani, Andreas Varkaris, John C. Araujo, Jian H. Song, Geralyn C. Trudel, Christopher Logothetis, Gary E. Gallick; The University of Texas MD Anderson Cancer Center, Houston, TX; Bristol-Myers Squibb, Montreal, QC, Canada. Serum insulin-like growth factor-1 levels in response to dasatinib-based regimens in bone-metastatic prostate cancer. Genitourninary Cancers Symposium, 2013.
- Paul G. Corn, Andreas Varkaris, Elsa M. Li Ning Tapia, John C. Araujo, Ana Aparicio, Shi-Ming Tu, Amado J. Zurita, Eleni Efstathiou, Wei Qiao, Sijin Wen, Gary E. Gallick, Christopher Logothetis; The University of Texas MD Anderson Cancer Center, Houston, TX; West Virginia University Health Science Center, Morgantown, WV. Modulation of soluble c-Met, bone turnover markers, angiogenic factors, and c-Met in men with mCRPC treated with cabozantinib. Genitourinary Cancers Symposium, 2013.
- John C. Araujo, Geralyn C. Trudel, Fred Saad, Andrew J. Armstrong, Evan Y. Yu, Joaquim Bellmunt, George Wilding, John McCaffrey, Sergio V. Serrano, Vsevolod Matveev, Eleni Efstathiou, Stephane Oudard, Michael J. Morris, Bruce Sizer, Peter J. Goebell, Johann Sebastian De Bono, Prashni Paliwal, Susan Durham, Shinta Cheng, Christopher Logothetis; Department of Genitourinary Medical Onology, University of Texas MD Anderson Cancer Center, Houston, TX; Bristol-Myers Squibb, Montreal, QC, Canada; Centre Hospitalier de l'Universite de Montreal, Montreal, QC, Canada; Duke Cancer Institute and the Duke Prostate Center, Division of Medical Oncology and Urology, Duke University, Durham, NC; University of Washington and Seattle Cancer Care Alliance, Seattle, WA; University Hospital del Mar-IMIM, Barcelona, Spain; University of Wisconsin Carbone Cancer Center, Madison, WI; Irish Clinical Oncology Research Group (ICORG), Dublin, Ireland; Hospital de Cancer de Barretos, Sao Paulo, Brazil; N.N. Blokhin Cancer Research Center, Moscow, Russia; Department of Clinical Therapeutics, The University of Athens, Athens, Greece; Department of Medical Oncology, Georges Pompidou European Hospital, Paris, France; Genitourinary Oncology Service, Memorial Sloan-Kettering Cancer Center, New York, NY; Essex County Hospital, Colchester, United Kingdom; Department of Urology, Friedrich-Alexander-Universitaet, Erlangen, Germany; Institute of Cancer Research/Royal Marsden Hospital, Sutton, United Kingdom; Bristol-Myers Squibb, Wallingford, CT; Bristol-Myers Squibb, Princeton, NJ. Overall survival (OS) and safety of dasatinib/docetaxel versus docetaxel in patients with metastatic castration-resistant prostate cancer (mCRPC): Results from the randomized phase III READY trial. Genitourinary Cancers Symposium, 2013.
- Dana E. Rathkopf, Matthew Raymond Smith, Johann Sebastian De Bono, Christopher Logothetis, Neal D. Shore, Paul L. De Souza, Karim Fizazi, Peter Mulders, Paul N. Mainwaring, John D. Hainsworth, Tomasz M. Beer, Scott A. North, Yves Fradet, Thomas W. Griffin, Youn Choi Park, Thian San Kheoh, Eric Jay Small, Howard I. Scher, Arturo Molina, Charles J. Ryan; Memorial Sloan-Kettering Cancer Center, New York, NY; Massachusetts General Hospital Cancer Center, Boston, MA; Institute of Cancer Research/Royal Marsden Hospital, Sutton, United Kingdom; The University of Texas MD Anderson Cancer Center, Houston, TX; Carolina Urologic Research Center, Myrtle Beach, SC; University of Western Sydney School of Medicine, Ingham Institute, Liverpool, Australia; Institut Gustave Roussy, Villejuif, France; Radboud University Medical Centre, Nijmegen, Netherlands; Haematology and Oncology Clinics of Australasia, Brisbane, Australia; Sarah Cannon Research Institute, Nashville, TN; Oregon Health and Science University, Knight Cancer Institute, Portland, OR; Cross Cancer Institute, Edmonton, AB, Canada; Laval University, Québec, QC, Canada; Janssen Research & Development, Los Angeles, CA; Janssen Research & Development, Raritan, NJ; Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, CA; University of California, San Francisco, San Francisco, CA. Updated interim analysis (IA) of COU-AA-302, a randomized phase III study of abiraterone acetate (AA) in patients (pts) with metastatic castration-resistant prostate cancer (mCRPC) without prior chemotherapy. Genitourninary Cancers Symposium, 2013.
- Ana M. Aparicio, Sankar Maity, Xuemei Wang, Anh G. Hoang, Eleni Efstathiou, Patricia Troncoso, Christopher J. Logothetis. A molecular characterization of the anaplastic prostate carcinomas. AACR, 2013.
- Ana M. Aparicio, Emily Gallichotte, Heather Cheng, Suk-Young Yoo, Sankar Maity, Christopher Logothetis, Muneesh Tewari. Circulating micro-RNAs can detect adaptive response to therapy and aggressive subset of prostate cancer. AACR, 2013.
- Nallasivam Palanisamy, Jun Yang, Xinhai Wan, John C. Araujo, Eleni Efstathiou, Louis Pisters, Ritu Bhalla, Scott Tomlins, Lakshmi P. Kunju, Arul Chinnaiyan, Christopher J. Logothetis, Patricia Troncoso, Nora M. Navone. Xenografts of human prostate cancer - a genetic profile analysis. AACR, 2013.
- Brittany N. Kleb, Marcos RH Estecio, Guanglin Wu, Jing-Fang Lu, Christopher J. Logothetis, Sankar Maity, Ana M. Aparicio. Mechanism of androgen receptor (AR) silencing in small cell prostate carcinoma. AACR, 2013.
- Xinhai Wan, Paul Corn, Jun Yang, Eleni Efstathiou, Elsa M. Li Ning Tapia, Fen Wang, Wallace McKeehan, Christopher Logothetis, Patricia Troncoso, Nora M. Navone. Fibroblast growth factor receptor blockade in prostate cancer bone metastases. AACR, 2013.
- Jeri Kim, John W. Davis, Eric A. Klein, Cristina Magi-Galluzzi, Yair Lotan, John F. Ward, Louis L. Pisters, Joseph W. Basler, Curtis A. Pettaway, Elsa M. Li Ning Tapia, Xuemei Wang, Kim-Anh Do, Jack Lee, Lana A. Vornik, Joe Tangrea, Howard L. Parnes, Scott M. Lippman, Ian M. Thompson, Powel H. Brown, Patricia Troncoso, Christopher J. Logothetis. A double-blind randomized controlled multisite trial evaluating tissue effects of preoperative finasteride in clinically organ-confined prostate cancer: Pathologic outcomes. AACR, 2013.
- Sankar N. Maity, Guanglin Wu, Jing-fang Lu, Joel R. Eisner, Stephen W. Rafferty, Robert J. Schotzinger, William R. Moore, Christopher J. Logothetis, John C. Araujo, Eleni Efstathiou. Efficacy of VT-464, a novel selective inhibitor of cytochrome P450 17,20-lyase, in castrate-resistant prostate cancer models. AACR, 2013.
- Jerome P. Richie; Robert B. Montgomery; Christopher J. Logothetis; Glenn J. Bubley; Bruce L. Dalkin; Martin G. Sanda; Massimo F. Loda; Rosina T. Lis; Lawrence D. True; Patricia Troncoso; Elizabeth M. Genega; Steven P. Balk; Elahe A. Mostaghel; Trevor M. Penning; Peter S. Nelson; Wanling Xie; Christopher M. Haqq; NamPhuong Tran; Weimin Peng; Daniel Tamae; Thian Kheoh; Arturo Molina; Philip W. Kantoff; Mary-Ellen Taplin. Effect of Neoadjuvant Abiraterone Acetate Plus Leuprolide Acetate on PSA, Pathologic Response, and Intraprostatic/Serum Androgen Levels in Localized High-Risk Prostate Cancer: Results of a Randomized Phase 2 Study. AUA, 2013.
- Neal Shore; Ethan Basch; Charles J. Ryan; Peter Mulders; Thian Kheoh; Karim Fizazi; Christopher J. Logothetis; Dana Rathkopf; Matthew R. Smith; Paul N. Mainwaring; Yanni Hao; Thomas Griffin; Susan Li; Michael L. Meyers; Arturo Molina; Charles Cleeland. The impact of abiraterone acetate therapy on patient-reported pain and functional status in chemotherapy-naïve patients with progressive, metastatic castration-resistant prostate cancer – results from an updated analysis. AUA, 2013.
- Fred Saad; Neal D Shore; Hendrik Van Poppel; Dana Rathkopf; Matthew R. Smith; Johann S. de Bono; Christopher Logothetis; Paul de Souza; Karim Fizazi; Peter FA Mulders; Paul Mainwaring; John D Hainsworth; Tomasz M Beer; Scott North; Yves Fradet; Tom Griffin; Thian Kheoh; Eric J Small; Howard I Scher; Arturo Molina; Charles J Ryan. Abiraterone acetate in metastatic castration-resistant prostate cancer patients without prior chemotherapy – Interim analysis of the COU-AA-302 phase 3 trial. AUA, 2013.
Book Chapters
- Logothetis CJ, Kim J, Davis JW, Chapin BF, Kuban D, Efstathiou E, Aparicio A. Neoplasms of the prostate. In: Holland-Frei Cancer Medicine 9th Edition. Ninth. Wiley-Blackwell, 1205-1235, 2017.
- Sanford RA, Abudayyeh A, Logothetis CJ, Tannir, NM. Urologic complications. In: Holland-Frei Cancer Medicine 9th Edition. Ninth. Wiley-Blackwell, 1755-1762, 2017.
- Bilen MA, Logothetis CJ, Corn PG. Chapter 37: Prostate Cancer. In: The MD Anderson Manual of Medical Oncology, Third Edition. Third. McGraw-Hill Education, 773-791, 2016.
- Logothetis CJ. Strategy for the application of therapy in prostate cancer. In: Adv Exp Med Biol, 193-9, 2008.
- Efstathiou E, Logothetis CJ. Clinical Challenges for Treatment and a Cure. In: The Biology and Treatment of Cancer. John Wiley & Sons, Inc, 155-67, 2008.
- Logothetis CJ, Assikis V, Sarriera JE. Urologic Complications. In: Holland-Frei Cancer Medicine 6th Editition. BC Decker Inc, 2003.
- Logothetis CJ, Moon C. Chapter 225-Endocrine Aspects of Prostate Cancer. In: Principles and Practice of Endocrinology and Metabolism, 2000.
- Logothetis CJ, Vogelzang NJ. Chapter 46B-Current Treatment and Investigative Approaches to the Management of Hormone-Refractory Prostate Cancer. In: Comprehensive Textbook of Genitourinary Oncology, 862-869, 1999.
- Hossan Eand Logothetis CJ. Chapter 10 - Management of hormone refractory disease. In: International Handbook of Prostate Cancer, 137-148, 1999.
- Scher HI, Logothetis CJ. Management of androgen-independent prostatic cancer. In: Principles and Practices of Genitourinary Oncology. Lippincott-Raven, 599-612, 1997.
- Logothetis CJ. Urological complications of malignancies and cancer therapy. In: Cancer Medicine 4th Edition. Williams and Wilkins, 3191-3196, 1997.
- Logothetis, CJ, Hoosein NM, Ro JY. Neuroendocrine progression of prostate cancer. In: Comprehensive Textbook of Genitourinary Oncology. Williams and Wilkins, 914-919, 1996.
- Denis L, Logothetis CJ. Urothelial cancer: The role of haematopoietic growth factors. In: Consultant Series - Urothelial Cancer. Gardiner-Caldwell Biotech, 1996.
- Amato RJ, Logothetis CJ. Chemotherapy for stage I and II testicular cancer. In: Comprehensive Textbook of Genitourinary Oncology. Williams and Wilkins, 1022-1027, 1996.
- Sella, A, Finn L, Amato R, Ellerhorst J, Zukiwski A, Kilbourn R, Logothetis CJ. Interferon- (IFN-) Combined with 5-Fluorouracil (5-FU) is an Active Regimen in Metastatic Renal Cell Cancer (RCC). In: Cancer Treatment: An Update. Springer-Verlag, 535-539, 1994.
- Amato, R, Finn L, Striegel A, Sella A, Ellerhorst J, Zukiwski A, Logothetis CJ. Salvage therapy in metastatic non-seminomatous germ cell tumour at the University of Texas M. D. Anderson Cancer Center. In: Germ Cell Tumours III, 271-272, 1994.
- Preti HA, Logothetis CJ. Testicular Cancer. In: Medical Oncology: A Comprehensive Review. PRR, Inc, 295-311, 1993.
- Logothetis CJ. The management of androgen-independent prostatic carcinoma. In: Prostate Diseases. W. B. Saunders Co, 364-3676, 1993.
- Dexeus F, Logothetis CJ. Penile carcinoma. In: Handbook of Chemotherapy in Clinical Oncology (2nd Edition). Scientific Communication International Ltd, 565-567, 1993.
- Sella, A, Amato RJ, Fitz K, Kilbourn RG, Logothetis CJ. Interferon-alpha and 5-fluorouracil combination chemotherapy for metastatic renal cell cancer. In: Interferons and Cytokines, 17-21, 1992.
- Kilbourn, RG, Owen-Schaub L, Griffith OW, Logothetis CJ. IL-2 mediated hypotension in the awake dog is reversed by inhibitors of nitric oxide formation. In: Second International Meeting - Biology of Nitric Oxide. Portland Press Ltd, 1991.
- Wallace, S, Charnsangavej C, Carrasco CH, Logothetis CJ. Intra-arterial chemotherapy of genitourinary tumors. In: Clinical Urography. W. B. Saunders Company, 3018-3026, 1990.
- Logothetis, CJ, Chong CD-K, Dexeus FH, Sella A, Ogden S. Intensive chemotherapy for metastatic nonseminomatous germ cell tumors. In: Uro-Oncology: Current Status and Future Trends. Alan R. Liss, Inc, 301-307, 1990.
- Logothetis, CJ, Dexeus FH, Chong CD-K, Sella A, Ogden S. The impact of chemotherapy on the survival of patients with metastatic urothelial tumors. In: Uro-Oncology: Current Status and Future Trends. Alan R. Liss, Inc, 107-114, 1990.
- von Eschenbach, AC, Johnson DE, Logothetis CJ. Prostate cancer: Commentary. In: Systemic Therapy for Genitourinary Cancers. Year Book Medical Publishers,, 251-254, 1989.
- Sella, A, Logothetis CJ, Dexeus FH, Amato RJ, Ogden S. Long-term cure rate in 154 testicular nonseminomatous germ cell tumor (NSGCTT) patients treated with aggressive chemotherapy. In: Proceedings of the 16th International Congress of Chemotherapy. June, 1989.
- Logothetis CJ, Ro JY. Germ cell tumors: Clinically relevant advances. In: Systemic Therapy for Genitourinary Cancers. Year Book Medical Publishers, 272-279, 1989.
- Logothetis, CJ, Johnson DE, von Eschenbach A. Germ cell tumors: Commentary. In: Systemic Therapy for Genitourinary Cancers. Year Book Medical Publishers, 380-384, 1989.
- Logothetis, CJ, Chong CDK, Ogden S. Long term follow-up of patients treated with cyclic CISCAII/VBIV at the University of Texas M. D. Anderson Cancer Center. In: Systemic Therapy for Genitourinary Cancers. Year Book Medical Publishers, 349-355, 1989.
- Logothetis, CJ, Swanson D, Ogden S. Primary chemotherapy for retroperitoneal nodal disease (clinical stage II). In: Systemic Therapy for Genitourinary Cancers. Year Book Medical Publishers, 326-330, 1989.
- Logothetis, CJ, Dexeus F, Chong C, Sella A, Finn L. Cytotoxic chemotherapy for hormone-refractory metastatic prostate cancer. In: Systemic Therapy for Genitourinary Cancers. Year Book Medical Publishers, 234-238, 1989.
- Logothetis CJ. Postoperative adjuvant CISCA chemotherapy for high risk invasive bladder cancer. In: Systemic Therapy for Genitourinary Cancers. Year Book Medical Publishers, 73-76, 1989.
- Logothetis CJ. CISCA chemotherapy for disseminated bladder carcinoma. In: Systemic Therapy for Genitourinary Cancers. Year Book Medical Publishers, 43-47, 1989.
- Johnson, DE, von Eschenbach A, Logothetis CJ. Renal cell carcinoma: Commentary. In: Systemic Therapy for Genitourinary Cancers. Year Book Medical Publishers, , 140-142, 1989.
- Johnson, DE, Logothetis CJ, von Eschenbach A. Urinary tract tumors: Commentary. In: Systemic Therapy for Genitourinary Cancers. Year Book Medical Publishers, 101-104, 1989.
- Dexeus, FH, Logothetis CJ, Sipahi H. Chemotherapy for advanced squamous carcinoma of the male external genital tract and urethra. In: Systemic Therapy for Genitourinary Cancers. Year Book Medical Publishers, 255-259, 1989.
- Chong C, Logothetis CJ. Chemotherapy for extragonadal germ cell tumors: The M. D. Anderson experience. In: Systemic Therapy for Genitourinary Cancers. Year Book Medical Publishers, 363-369, 1989.
- Chong CDK, Logothetis CJ. Cisplatin-based chemotherapy for metastatic pure seminoma. In: Systemic Therapy for Genitourinary Cancers. Year Book Medical Publishers, , 280-285, 1989.
- Chong C, Logothetis CJ. Treatment of advanced transitional cell carcinoma of the renal pelvis and ureter. In: Systemic Therapy for Genitourinary Cancers. Year Book Medical Publishers, 94-100, 1989.
- Swanson DA, Logothetis CJ. Primary chemotherapy for clinical stage II nonseminomatous testicular carcinoma. In: Advances in Urology. Year Book Medical Publishers, Inc, 129-144, 1988.
- Logothetis, CJ, Chong C, Dexeus FH, Sella A, Ogden S. Intensive chemotherapy for metastatic nonseminomatous germ cell tumors. In: Uro-Oncology: Current Status and Future Trends. Alan R. Liss, Inc, 301-307, 1988.
- Swanson DA, Logothetis CJ. Metastatic transitional cell carcinoma. In: Current Therapy in Genitourinary Surgery. B. C. Decker Inc, 69-73, 1987.
- Logothetis CJ. Testicular cancer. In: Cancer Update 87: Committee of Medical Oncology Fellows Board Review, M. D. Anderson Hospital and Tumor Institute, 1987.
- Logothetis, CJ, Johnson DE, Chong C, Dexeus FH, Ogden S, von Eschenbach AC, Ayala AG. Adjuvant CISCA for patients with high risk bladder cancer. In: Adjuvant Therapy of Cancer V. . Grune and Stratton, Inc, 565-570, 1987.
- Logothetis CJ. Vinblastine and bleomycin combination in the management of germ cell tumors (Part I); Prostatic carcinoma (Part II); Urothelial tumors (Part III). In: Cancer Chemotherapy by Infusion. Precept Press Inc, 353-367, 1987.
- Logothetis CJ. Testicular cancer and other tumors of the male genitourinary tract. In: Cancer Chemotherapy by Infusion. Precept Press Inc, 353-367, 1987.
- Logothetis CJ. Extragonadal germ cell tumors. In: Principles and Management of Testicular Cancer. Thieme Inc, 355-350, 1986.
- Johnson, DE, Logothetis CJ, Zagars GK, Smith DB. Special problems posed by cancer treatments. In: Ostomy Care and the Cancer Patient. Surgical and Clinical Considerations. Grune and Stratton, Inc, 121-131, 1986.
- Logothetis CJ. Perioperative chemotherapy for the management of primary local regional urothelial tumors. In: Primary Chemotherapy in Cancer Medicine. Alan R. Liss, Inc, 359-366, 1985.
- Logothetis CJ. Preoperative chemotherapy in the treatment of germinal tumors. In: Primary Chemotherapy in Cancer Medicine. Alan R. Liss, Inc, 341-350, 1985.
- Logothetis, CJ, von Eschenbach AC, Samuels ML, Trindade A, Johnson DE. Doxorubicin, mitomycin, and 5-FU (DMF) in the treatment of hormone-resistant stage D prostate cancer: A preliminary report. In: Year Book of Cancer, 134-136, 1983.
Letters to the Editor
- Logothetis CJ, Hahn AW. Reply to Richard J. Wassersug, Paul F. Schellhammer, and Erik Wibowo's Letter to the Editor re: Christoper J. Logothetis, Andrew W. Hahn. Challenging the Prevailing Therapeutic Dogma for Prostate Cancer: The Case for an Overlap Syndrome. Eur Urol 2024;85:3-7. Eur Urol 85: e175, 2024.
- Pagliaro LC, Tannir NM, Tu SM, Logothetis CJ. Management of Clinical Stage I Testicular Cancer: How Should We Define Success?. J Clin Oncol 33: 2321-2, 2015.
- Tu SM, Lin SH, Logothetis C. Re: A randomized, placebo-controlled trial of zoledronic acid in patients with hormone-refractory metastatic prostate carcinoma. J Natl Cancer Inst 95: 1174-5; author reply 1175, 2003.
- von Eschenbach AC, Logothetis CJ. Prostate Cancer. Cancer Bulletin 45: 379-380, 1993.
- Logothetis CJ, Amato RJ. Dose intensity in germ cell tumors: lessons learned?. J Natl Cancer Inst 84: 1686-7, 1992.
- Logothetis CJ. Neoadjuvant Chemotherapy in Invasive Bladder Cancer: Progress in Clinical and Biological Research. Journal of the National Cancer Institute 83: 786, 1991.
- Logothetis CJ. Organ Preservation in Bladder Carcinoma: A Matter of Selection. Journal of Clinical Oncology 9: 1525-1526, 1991.
- Sella A, Logothetis CJ, Dexeus FH, Amato R. Pulmonary air cyst associated with combination chemotherapy containing bleomycin. AJR Am J Roentgenol 153: 191, 1989.
- Logothetis CJ. Adjuvant chemotherapy for testicular cancer. N Engl J Med 319: 53, 1988.
- Logothetis CJ. Carcinoma-in-situ of the testis. Lancet 2: 977, 1987.
- Logothetis CJ. Have aggressive chemotherapy regimens improved results in advanced germ cell tumors. Eur J Cancer Clin Oncol 23: 1415-6, 1987.
- Logothetis CJ. Lhermittes sign following cisplatin therapy for a patient with CISCAII/VBIV (editorial). American Journal of Medicine 82: 575-576, 1987.
- Logothetis CJ, Samuels ML. Prognostic factors in disseminated germ cell tumors. J Clin Oncol 4: 1278-80, 1986.
- Logothetis CJ. Endodermal sinus tumors. Chest 88: 6-7, 1985.
- Logothetis CJ. Bladder cancer histology reported to influence response to treatment (editorial). Urology Times 1: 380, 1984.
Grant & Contract Support
Title: | MD Anderson Cancer Center Prostate Cancer SPORE Core A: Administrative Core |
Funding Source: | NIH/NCI |
Role: | Principal Investigator |
Title: | Osteocrines in Therapy Resistance of Prostate Cancer Bone Metastasis: Evaluation of Strategies to Overcome Therapy Resistance from Tumor-Educated Bone Environment |
Funding Source: | PCF-Janssen Special Challenge Award |
Role: | Co-Principal Investigator |
Title: | A Phase 3 Ct, Randomized, Double Blind, Placebo-Controlled Study of Abiraterone Acetate (CB7630) Plus Prednisone in Asymptomatic or Mildly Symptomatic Patients with Metastatic Castration-Resistant Prostate Cancer |
Funding Source: | Cougar Biotechnology |
Role: | Principal Investigator |
Title: | A Randomized, Open Label, Neoadjuvant Prostate Cancer Trial of Abiraterone Acetate Plus LHRHa Versus LHRHa Alone (COU-AA-203) |
Funding Source: | Cougar Biotechnology |
Role: | Principal Investigator |
Title: | An Open Label Study of Abiraterone Acetate in Subjects with Metastatic Castration-Resistant Prostate Cancer Who have Progressed After Taxane-Based Chemotherapy |
Funding Source: | Cougar Biotechnology/Johnson & Johnson |
Role: | Principal Investigator |
Title: | Cancer Center Support (CORE) Grant - Prostate Cancer Program |
Funding Source: | NIH/NCI |
Role: | Program Leader, Prostate Cancer Program |
Title: | Mechanisms of de Novo and Acquired Resistance to Therapeutic Treatment of Bone-Metastatic Prostate Cancer |
Funding Source: | Cancer Prevention & Research Institute of Texas (CPRIT) |
Role: | Collaborator |
Title: | Prostate Cancer Moon Shot: Integrated Plan for Reducing Mortality of Advanced Prostate Cancer |
Funding Source: | MD Anderson Moon Shot Program |
Role: | Co-Principal Investigator |
Title: | Regulation of Dormancy of Metastatic Prostate Cancer Cells by Bone Microenvironment |
Funding Source: | Cancer Prevention & Research Institute of Texas (CPRIT) |
Role: | Collaborator |
Title: | A Phase 2 Study Determining Safety and Tolerability of Enzalutamide (formerly MDV3100) in Combination with Abiraterone Acetate in Bone Metastatic Castration-Resistant Prostate Cancer Patients (9785-CL-0011) |
Funding Source: | Astellas Pharma US Inc |
Role: | Principal Investigator |
Title: | A Pre-Op Study to Assess the Effects of Abiraterone Acetate + LHRH Agonist and Abiraterone |
Funding Source: | Janssen Biotech, Inc |
Role: | Principal Investigator |
Title: | Expansion of Stanford Alexander Tissue Derivatives Laboratory |
Funding Source: | The Stanford and Joan Alexander Fam Fund |
Role: | Principal Investigator |
Title: | Identifying Markers for Early Prediction of Prostate Cancer Bone Metastases in Prostate Cancer from Analyses of the Tumor-Associated Microenvironments |
Funding Source: | Prostate Cancer Foundation |
Role: | Co-Principal Investigator |
Title: | Flagship 1: Optimizing Androgen Signaling Inhibition to Transition from a Treatment to Curative Paradigm |
Funding Source: | MD Anderson Moon Shot Program |
Role: | Co-Principal Investigator |
Title: | Flagship 2: Targeting the Immune and Non-Immune Tumor-Associated Microenvironments in Prostate Cancer |
Funding Source: | MD Anderson Moon Shot Program |
Role: | Co-Principal Investigator |
Title: | MD Anderson Cancer Center Prostate Cancer SPORE |
Funding Source: | NIH/NCI |
Role: | Multiple Principal Investigator; Clinical Co-Leader, Project 3 (0.60 CM); Administrative Core (1.20 CM); Co-Director, DRP (0.30 CM); Co-Director, CEP (0.30 CM) |
Title: | Standardized Quantitative Imaging Biomarkers for Co-Clinical Trials |
Funding Source: | NIH/NCI |
Role: | Co-Investigator |
Title: | Patient-Derived Models of Prostate Cancer for Personalized Medicine |
Funding Source: | NIH/NCI |
Role: | Co-Investigator |
Title: | Anti-Androgens Treatment Enhances Cytotoxicity of Oxidative-Phosphorylation Inhibitors Against Castration Resistant Prostate Cancer |
Funding Source: | Department of Defense (DOD) |
Role: | Principal Investigator |
Title: | Targeting m6A RNA epigenetics in treatment-emergent neuroendocrine prostate cancer |
Funding Source: | NIH/NCI |
Role: | Co-Investigator |
Title: | Prostate Cancer Moon Shot |
Funding Source: | MD Anderson Moon Shot |
Role: | Clinical Leader |
Title: | MD Anderson Cancer Center Prostate Cancer SPORE |
Funding Source: | NIH/NCI |
Role: | Co-Principal Investigator |
Title: | Statistical Methods for Genomic Analysis of Heterogeneous Tumors |
Funding Source: | NIH/NCI |
Role: | Co-Investigator |
Title: | Imaging Metabolic Reprogramming in Prostate Cancer |
Funding Source: | Cancer Prevention & Research Institute of Texas (CPRIT) |
Role: | Collaborator |
Title: | Mechanisms and Therapies Focused on Epigenomic Alterations in Therapy-Resistant Prostate Cancers |
Funding Source: | Cancer Prevention & Research Institute of Texas (CPRIT) |
Role: | Collaborator |
Title: | Drugging the Enzymes of the Ketogenic/Ketolytic Pathways for Castration-Resistant Prostate Cancer Therapy |
Funding Source: | Prostate Cancer Foundation |
Role: | Collaborator |
Title: | Targeting Prostate Tumor-induced Bone Formation and the Immunosuppressive Microenvironment to Improve the Efficacy of Immune Checkpoint Therapies |
Funding Source: | Prostate Cancer Foundation |
Role: | Co-Principal Investigator |
Title: | Imaging Metabolic Reprogramming in Prostate Cancer |
Funding Source: | Cancer Prevention & Research Institute of Texas (CPRIT) |
Role: | Co-Investigator |