Christopher Young
Department of Neurosurgery, Division of Surgery
About Christopher Young
Christopher Young, MD PhD, is an assistant professor in the Department of Neurosurgery who specializes in conditions affecting blood vessels in the brain and spine. These include management of ischemic and hemorrhagic strokes, cerebral aneurysms, vascular malformations and subdural hematomas, as well as emerging cerebrovascular techniques for the treatment of brain and spinal tumors.
Dr. Young received his medical degree from the University of Cape Town. He obtained a PhD at the University of Oxford where he was a Rhodes Scholar and worked on molecular regulation of neural stem cells after ischemic stroke. He completed neurosurgery residency at the University of Washington and postgraduate fellowship in endovascular neurosurgery at the Johns Hopkins Hospital. A dual-trained cerebrovascular neurosurgeon, he offers both open surgical approaches and minimally invasive endovascular techniques to treat a variety of central nervous system disorders, with emphasis on treatments tailored to the needs of patients with cancer.
As a surgeon-scientist, Dr. Young is interested in novel endovascular indications for treatment of CNS disorders. His lab focuses on the molecular interface between the vasculature and the brain, as well as application of this knowledge for cerebrovascular diseases and neuro-oncology.
Present Title & Affiliation
Primary Appointment
Assistant Professor, Department of Neurosurgery, Division of Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX
Dual/Joint/Adjunct Appointment
Assistant Professor, Department of Neurosurgery, University of Texas Medical Branch, Houston, TX
Education & Training
Degree-Granting Education
| 2011 | University of Oxford, Oxford, GBR, PhD, Doctor of Philosophy |
| 2008 | University of Oxford, Oxford, GBR, MSc, Master of Science |
| 2005 | University of Cape Town, Cape Town, ZAF, MBChB, Bachelor of Medicine and Bachelor of Surgery |
Postgraduate Training
| 2022-2023 | Endovascular Neurosurgery Fellowship (Year 2), The Johns Hopkins Hospital, Baltimore, MD |
| 2021-2022 | Clinical Residency, Chief Resident, Neurologic Surgery, University of Washington, Seattle, WA |
| 2019-2020 | Endovascular Neurosurgery Fellowship (Enfolded Year 1), University of Washington, Seattle |
| 2015-2022 | Clinical Residency, Neurologic Surgery, University of Washington, Seattle, WA |
Honors & Awards
| 2023 | Gold Medal for Neuroanesthesia, University of Washington, Dept. of Anesthesia |
| 2019 | CV Section Robert J. Dempsey AANS Cerebrovascular Research Award, American Association of Neurologic Surgeons |
| 2019 | Cerebrovascular Research Grant, Bee Aneurysm Foundation |
| 2011 | Sherrington Prize, University of Oxford, Dept of Physiology, Anatomy and Genetics |
| 2010 | IBRO Student Research Award, Federation of European Neurosciences Societies |
| 2009 | MD/PhD Research Award, Days of Molecular Medicine Conference, Massachusetts General Hospital/Harvard Medical School |
| 2009 | Old Members' Graduate Travel Scholarship, University College, University of Oxford |
| 2007 | Rhodes Scholar, The Rhodes Trust/University of Oxford UK |
| 2000 | Academic Scholarship, University of Cape Town Medical School, SA |
Selected Publications
Peer-Reviewed Articles
- Young CC, Kan P, Chen SR, Lang FF. Endovascular surgical neuro-oncology: advancing a new subspecialty. J Neurooncol 170(1):31-40, 2024. e-Pub 2024. PMID: 39222190.
- Yang W, Lee RP, Hung AL, Young CC, Sattari SA, Urrutia V, Gailloud PE, Xu R, Caplan J, Gonzalez LF. Cost-Effectiveness of a Direct-Aspiration First-Pass Technique versus Stent Retriever in Mechanical Thrombectomy. World Neurosurg 183:e495-e501, 2024. e-Pub 2023. PMID: 38159607.
- Akiyama LF, Roberts EA, Shurtleff HA, Barry D, Saneto RP, Novotny EJ, Young CC, Warner MH, Hauptman JS, Ojemann JG, Marashly A. Clinical outcomes of pediatric hemispherectomy following unsuccessful subhemispheric resection for refractory epilepsy: a case review study. J Neurosurg Pediatr 32(3):358-365, 2023. e-Pub 2023. PMID: 37310054.
- King D, Adidharma L, Peng H, Moe K, Li Y, Yang Z, Young C, Ferreria M, Humphreys I, Abuzeid WM, Hannaford B, Bly RA. Automatic summarization of endoscopic skull base surgical videos through object detection and hidden Markov modeling. Comput Med Imaging Graph 108:102248, 2023. e-Pub 2023. PMID: 37315397.
- Eaton JC, Meyer RM, Lim DH, Greil ME, Williams JR, Young CC, Barber JK, Temkin NR, Bonow RH, Chesnut RM. Acute Extra-Arachnoid Subdural Hematomas in Patients 50 Years and Older: When Subdurals Act Like Epidurals. World Neurosurg. e-Pub 2023. PMID: 37683917.
- Srinivas T, Ran K, Nair SK, Hung A, Young CC, Tamargo RJ, Huang J, Marsh E, Hillis A, Yedavalli V, Urrutia V, Gailloud P, Caplan JM, Gonzalez LF, Xu R. Racial disparities in functional outcomes following mechanical thrombectomy in a cohort of patients with ischemic stroke. J Neurointerv Surg. e-Pub 2023. PMID: 37532451.
- Sattari SA, Antar A, Sattari AR, Feghali J, Hung A, Lee RP, Yang W, Kim JE, Johnson E, Young CC, Xu R, Caplan JM, Huang J, Tamargo RJ, Gonzalez LF. Endovascular Thrombectomy versus Endovascular Thrombectomy Preceded by Intravenous Thrombolysis: A Systematic Review and Meta-Analysis. World Neurosurg 177:39-58. e-Pub 2023. PMID: 37201784.
- Young CC, Bass DI, Cruz MJ, Carroll K, Vanent KN, Lee C, Sen RD, Feroze AH, Williams JR, Levy S, McCray D, Kelly CM, Barber J, Kim LJ, Levitt MR. Clopidogrel hyper-response increases peripheral hemorrhagic complications without increasing intracranial complications in endovascular aneurysm treatments requiring dual antiplatelet therapy. J Clin Neurosci 105:66-72, 2022. e-Pub 2022. PMID: 36113244.
- Shenoy VS, Young CC, Miller CA, Ghodke BV, Sekhar LN. Microsurgical Clipping and Intracranial A4 to A4 Rescue Bypass for a Complex Anterior Communicating Artery Aneurysm Previously Treated With Endovascular Coiling: 2-Dimensional Video. Oper Neurosurg (Hagerstown) 23(2):e125, 2022. e-Pub 2022. PMID: 35838469.
- McAvoy M, Lee G, Boop S, Greil ME, Durler KA, Young CC, Craft L, Chesnut RM, Wahlster S. Fixed, Dilated, and Conversing-Unreactive Pupil With Preserved Consciousness Indicating Acutely Rising Intracranial Pressure due to Traumatic Intraparenchymal Contusions: Case Report and Review of the Literature. Neurohospitalist 12(2):355-360, 2022. e-Pub 2021. PMID: 35419147.
- Bass DI, Young CC, Park MS, Cruz MJ, Carroll KT, Vanent KN, Lee C, Sen RD, Angiolillo DJ, Cattaneo M, Kim LJ, Levitt MR. Severe, Intolerable Fatigue Associated with Hyperresponse to Clopidogrel. World Neurosurg 156:e374-e380, 2021. e-Pub 2021. PMID: 34563718.
- Soares LC, Al-Dalahmah O, Hillis J, Young CC, Asbed I, Sakaguchi M, O'Neill E, Szele FG. Novel Galectin-3 Roles in Neurogenesis, Inflammation and Neurological Diseases. Cells 10(11), 2021. e-Pub 2021. PMID: 34831271.
- Williams JR, Nieblas-Bedolla E, Feroze A, Young C, Temkin NR, Giacino JT, Okonkwo DO, Manley GT, Barber J, Durfy S, Markowitz AJ, Yuh EL, Mukherjee P, Mac Donald CL, and The Transforming Research and Clinical Knowledge in Traumatic Brain Injury (TRACK-TBI) Investigators. Prognostic Value of Hemorrhagic Brainstem Injury on Early Computed Tomography: A TRACK-TBI Study. Neurocrit Care 35(2):335-346, 2021. e-Pub 2021. PMID: 34309784.
- Shurtleff HA, Roberts EA, Young CC, Barry D, Warner MH, Saneto RP, Buckley R, Firman T, Poliakov AV, Ellenbogen RG, Hauptman JS, Ojemann JG, Marashly A. Pediatric hemispherectomy outcome: Adaptive functioning, intelligence, and memory. Epilepsy Behav 124:108298. e-Pub 2021. PMID: 34537627.
- Williams JR, Meyer MR, Ricard JA, Sen R, Young CC, Feroze AH, Greil ME, Barros G, Durfy S, Hanak B, Morton RP, Temkin NR, Barber JK, Mac Donald CL, Chesnut RM. Re-examining decompressive craniectomy medial margin distance from midline as a metric for calculating the risk of post-traumatic hydrocephalus. J Clin Neurosci 87:125-131, 2021. e-Pub 2021. PMID: 33863519.
- Lu VM, Chen SH, Young CC, Starke RM. Nature, content and shifts over time of the most impactful unruptured intracranial aneurysms articles: a bibliometric analysis. J Neurointerv Surg 13(2):177-181, 2021. e-Pub 2020. PMID: 32606102.
- Lu VM, Carlstrom LP, Perry A, Graffeo CS, Domingo RA, Young CC, Meyer FB. Prognostic significance of subdural hygroma for post-traumatic hydrocephalus after decompressive craniectomy in the traumatic brain injury setting: a systematic review and meta-analysis. Neurosurg Rev 44(1):129-138, 2021. e-Pub 2019. PMID: 31845199.
- Aljuboori ZS, Young CC, Srinivasan VM, Kellogg RT, Quon JL, Alshareef MA, Chen SH, Ivan M, Grant GA, McEvoy SD, Davanzo JR, Majid S, Durfy S, Levitt MR, Sieg EP, Ellenbogen RG, Nauta HJ. Early Effects of COVID-19 Pandemic on Neurosurgical Training in the United States: A Case Volume Analysis of 8 Programs. World Neurosurg 145:e202-e208, 2021. e-Pub 2020. PMID: 33065350.
- Li Y, Chen SH, Spiotta AM, Jabbour P, Levitt MR, Kan P, Griessenauer CJ, Arthur AS, Osbun JW, Park MS, Chalouhi N, Sweid A, Wolfe SQ, Fargen KM, Dumont AS, Dumont TM, Brunet MC, Sur S, Luther E, Strickland A, Yavagal DR, Peterson EC, Schirmer CM, Goren O, Dalal S, Weiner G, Rosengart A, Raper D, Chen CJ, Amenta P, Scullen T, Kelly CM, Young C, Nahhas M, Almallouhi E, Gunasekaran A, Pai S, Lanzino G, Brinjikji W, Abbasi M, Dornbos Iii D, Goyal N, Peterson J, El-Ghanem MH, Starke RM. Lower complication rates associated with transradial versus transfemoral flow diverting stent placement. J Neurointerv Surg 13(1):91-95, 2021. e-Pub 2020. PMID: 32487766.
- Almallouhi E, Al Kasab S, Sattur MG, Lena J, Jabbour PM, Sweid A, Chalouhi N, Gooch MR, Starke RM, Peterson EC, Yavagal DR, Chen SH, Li Y, Gross BA, Tonetti DA, Zussman BM, Stone JG, Jadhav AP, Jankowitz BT, Young CC, Lim DH, Levitt MR, Osbun JW, Spiotta AM. Incorporation of transradial approach in neuroendovascular procedures: defining benchmarks for rates of complications and conversion to femoral access. J Neurointerv Surg 12(11):1122-1126, 2020. e-Pub 2020. PMID: 32217626.
- Young CC, Hofstetter CP. Traumatic Fetal Subdural Hematoma and Unstable Maternal Spine Fracture. World Neurosurg 142:368-370, 2020. e-Pub 2020. PMID: 32683009.
- Lu VM, Young CC, Chen SH, O'Connor KP, Silva MA, Starke RM. Presenting NIHSS predicts 90-day functional outcome after mechanical thrombectomy for basilar artery occlusion: A systematic review and meta-analysis. Clin Neurol Neurosurg 197:106199, 2020. e-Pub 2020. PMID: 32916397.
- Srinivasan VM, Hadley CC, Prablek M, LoPresti M, Chen SH, Peterson EC, Sweid A, Jabbour P, Young C, Levitt M, Osbun JW, Burkhardt JK, Johnson J, Kan P. Feasibility and safety of transradial access for pediatric neurointerventions. J Neurointerv Surg 12(9):893-896, 2020. e-Pub 2020. PMID: 32241922.
- Walker M, Young CC, Levitt MR, Saal-Zapata G. Multiple Sclerosis in Patients with Intracranial Aneurysms: Coincidence or Correlation?. Clin Neurol Neurosurg 195:105864, 2020. e-Pub 2020. PMID: 32361026.
- Young CC, Williams JR, Feroze AH, McGrath M, Ravanpay AC, Ellenbogen RG, Ojemann JG, Hauptman JS. Pediatric functional hemispherectomy: operative techniques and complication avoidance. Neurosurg Focus 48(4):E9, 2020. PMID: 32234987.
- Williams JR, Young CC, Vitanza NA, McGrath M, Feroze AH, Browd SR, Hauptman JS. Progress in diffuse intrinsic pontine glioma: advocating for stereotactic biopsy in the standard of care. Neurosurg Focus 48(1):E4, 2020. PMID: 31896081.
- Feroze AH, McGrath M, Williams JR, Young CC, Ene CI, Buckley RT, Cole BL, Ojemann JG, Hauptman JS. Laser interstitial thermal therapy for pediatric atypical teratoid/rhabdoid tumor: case report. Neurosurg Focus 48(1):E11, 2020. PMID: 31896085.
- Young CC, Bonow RH, Barros G, Mossa-Basha M, Kim LJ, Levitt MR. Magnetic resonance vessel wall imaging in cerebrovascular diseases. Neurosurg Focus 47(6):E4, 2019. e-Pub 2019. PMID: 31846249.
- Bonow RH, Young CC, Bass DI, Moore A, Levitt MR. Transcranial Doppler ultrasonography in neurological surgery and neurocritical care. Neurosurg Focus 47(6):E2, 2019. PMID: 31786564.
- Chu JK, Feroze AH, Collins K, McGrath LB, Young CC, Williams JR, Browd SR. Variation in hospital charges in patients with external ventricular drains: comparison between the intensive care and surgical floor settings. J Neurosurg Pediatr 24(1):29-34, 2019. PMID: 31003227.
- Young CC, Ellenbogen RG, Hauptman JS. Acute traumatic presentation of Chiari I malformation with central cord syndrome and presyrinx in an infant. Surg Neurol Int 10:253, 2019. e-Pub 2019. PMID: 31893154.
- Young CC, Morton RP, Ghodke BV, Levitt MR. Retrograde 3D rotational venography (3DRV) for venous sinus stent placement in idiopathic intracranial hypertension. J Neurointerv Surg 10(8):777-779, 2018. e-Pub 2017. PMID: 29175828.
- Young CC, Hanak BW, Patel AP, Sekhar LN. Rapid Intraoperative in Situ Synthetic Cranioplasty. World Neurosurg 112:161-165, 2018. e-Pub 2018. PMID: 29409926.
- Losey P, Young C, Krimholtz E, Bordet R, Anthony DC. The role of hemorrhage following spinal-cord injury. Brain Res 1569:9-18, 2014. e-Pub 2014. PMID: 24792308.
- Young CC, Al-Dalahmah O, Lewis NJ, Brooks KJ, Jenkins MM, Poirier F, Buchan AM, Szele FG. Blocked angiogenesis in Galectin-3 null mice does not alter cellular and behavioral recovery after middle cerebral artery occlusion stroke. Neurobiol Dis 63:155-64, 2014. e-Pub 2013. PMID: 24269916.
- Young CC, van der Harg JM, Lewis NJ, Brooks KJ, Buchan AM, Szele FG. Ependymal ciliary dysfunction and reactive astrocytosis in a reorganized subventricular zone after stroke. Cereb Cortex 23(3):647-59, 2013. e-Pub 2012. PMID: 22414771.
- Comte I, Kim Y, Young CC, van der Harg JM, Hockberger P, Bolam PJ, Poirier F, Szele FG. Galectin-3 maintains cell motility from the subventricular zone to the olfactory bulb. J Cell Sci 124(Pt 14):2438-47, 2011. e-Pub 2011. PMID: 21693585.
- Young CC, Brooks KJ, Buchan AM, Szele FG. Cellular and molecular determinants of stroke-induced changes in subventricular zone cell migration. Antioxid Redox Signal 14(10):1877-88, 2011. e-Pub 2010. PMID: 20673127.
Book Chapters
- Bass DI, Young CC, Sen RD, Levitt MR. Transarterial Embolization. In: Cerebral Dural Arteriovenous Fistulas (Chapter 5). 1st. Elsevier: New York, 2021.
- Abecassis IJ, Young CC, Sen RD, Kelly CM, Levitt MR. Radiation-Induced Stenosis (Ch. 8). In: Carotid Artery Disease. Springer, 113-123, 2020.
- Young, C. C., & Ko, A. L.. Dorsal root entry zone lesioning for brachial plexus avulsion pain (Ch. 11). In: Functional Neurosurgery and Neuromodulation. Elsevier, 77-84, 2018.
- IJ Abecassis, CC Young MR Levitt, LJ Kim. Complication Avoidance and Management of Endovascular Treatments (Ch. 27). In: Intracranial Aneurysms. Elsevier: New York, 431-460, 2018.
- Young CC, Chiarelli PA, Hofstetter CP. Injuries to the Cervical Spine (Ch. 29). In: Neurological Surgery. 4. Elsevier: New York, 2018.
- Young CC, Smith TR, Bi WL, Dunn IF, Laws ER.. Historical Aspects (Ch. 1). In: Chordomas: Technologies, Techniques, and Treatment Strategies. Thieme Publishers: New York, 2016.
- Ruo-Li Chen, Joyce S. Balami, Christopher Young, Shih-Hwa Chiou, Yueh Chien, Liang-Kung Chen, Francis Szele, Alastair M. Buchan. Stem Cell Therapy for Ischaemic Stroke in the Elderly (Ch. 4). In: Advances in Medicine and Biology. Nova Science, 125-144, 2012.
Patient Reviews
CV information above last modified November 20, 2024