Di (Andy) Ai, MD, PhD
Department of Anatomical Pathology, Division of Pathology-Lab Medicine Div
About Dr. Di Ai
In addition to my clinical practice in pathology, I have a strong interest in research, with experience spanning basic, translational, and clinical domains. My basic science research focused on the WNT signaling pathway in developmental biology and mouse genetics, utilizing genetically engineered mouse models. In translational research, I investigated the role of platelet-derived growth factor receptors (PDGFR) in maintaining cardiac function under mechanical stress. My clinical research experience includes identifying a novel diagnostic immunohistochemical marker (TRPS1) in breast cancer, studying chromosome 3 abnormalities in patients with chronic myeloid leukemia, and contributing to large-scale clinical trials such as POISE-II (NCT00860925).
I am a breast pathology fellowship–trained pathologist currently practicing at the University of Texas MD Anderson Cancer Center. We evaluate more than three thousand breast resection specimens annually, the majority of which are estrogen receptor (ER) and/or progesterone receptor (PR) positive. Immunohistochemical analysis for biomarkers such as ER and PR is routinely performed on all malignancies, and tumor profiling via molecular testing guides clinical management, particularly in ER-positive, Human Epidermal Growth Factor Receptor 2 (HER2)-negative disease. Leveraging access to well-annotated breast tumor specimens, my current translational research centers on gene regulation and dysregulated signaling pathways across distinct breast cancer subtypes, including ER-positive, HER2-positive, and triple-negative breast cancer.
Present Title & Affiliation
Primary Appointment
Assistant Professor, Department of Anatomical Pathology, Division of Pathology and Laboratory Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas
Dual/Joint/Adjunct Appointment
Assistant Professor, Department of Anatomic Pathology, The University of Texas MD Anderson Cancer Center, Houston, Texas
Education & Training
Degree-Granting Education
| 2007 | Texas A&M Health Science Center, Houston, Texas, US, Medical Science, PhD |
| 1999 | Nanjing Medical University, Nanjing, Jiangsu, CN, Clinical Medicine, MD |
Postgraduate Training
| 2020-2021 | Breast Pathology Fellowship, The University of Texas MD Anderson Cancer Center; Houston, Texas |
| 2019-2020 | Oncologic Surgical Pathology Fellowship, The University of Texas MD Anderson Cancer Center; Houston, Texas |
| 2015-2019 | Pathology Residency, Baylor Scott & White Medical Center, Temple, Texas |
| 2012-2014 | Clinical Research Fellow, The University of Texas MD Anderson Cancer Center, Houston, Texas |
| 2007-2010 | Postdoctoral Research Fellow, The University of Texas MD Anderson Cancer Center, Houston, Texas |
| 1999-2001 | Internal Medicine Residency, Jiangsu Province Hospital, Nanjing, Jiangsu |
Licenses & Certifications
| 2023 | Texas Medical Board |
| 2021 | Georgia Composite Medical Board |
| 2021 | American Board of Pathology |
Experience & Service
Faculty Academic Appointments
Assistant Professor, Department of Pathology and Laboratory Medicine, The University of Texas Health Science Center at Houston, Houston, Texas, 2023 - 2025
Assistant Professor, Department of Pathology and Laboratory Medicine, Emory University, Atlanta, Geogia, 2021 - 2023
Intramural Institutional Committee Activities
Committee Member, Medical School Admissions Committee, McGovern Medical School at UTHealth Houston, 2024 - 2027
Committee Member, Conflict of Interest and Commitment Office Committee, Emory University, 2022 - 2023
Extramural Institutional Committee Activities
Board Member, Board of Directors, Chinese American Pathologists Association (CAPA), 2026 - 2028
Committee Member, Membership Committee, Society of Chinese Bioscientists in America (SCBA), 2026 - 2028
Associate Director, Breast Pathology Subcommittee, Chinese American Pathologists Association (CAPA), 2026 - 2027
Associate Director, IT and Website Subcommittee, Chinese American Pathologists Association (CAPA), 2026 - 2027
Director, Immunohistochemistry Subcommittee, Chinese American Pathologists Association (CAPA), 2024 - 2025
Director, IT and Website Subcommittee, Chinese American Pathologists Association (CAPA), 2023 - 2024
Associate Director, IT and Website Subcommittee, Chinese American Pathologists Association (CAPA), 2022 - 2023
Committee Member, Georgia Association of Pathology, Georgia Association of Pathology, 2021 - 2023
Associate Director, Membership and Operation Subcommittee, Chinese American Pathologists Association (CAPA), 2021 - 2022
Editorial Activities
Associate Editor, Clinical Pathology & Research Journal, 2023 - Present
Honors & Awards
| 2024 | Service Award, Chinese American Pathologists Association (CAPA); Baltimore, MD |
| 2017 | Travel Award, Baylor Scott & White Medical Center; Temple, TX |
| 2017 | TSP Educational Foundation Scholarship, Texas Society of Pathologists (TSP); Temple, TX |
| 2016 | Travel Award, Baylor Scott & White Medical Center; Temple, TX |
| 2016 | The Highest Ranked Breast Pathology Abstract Award (Clinical Science), International Society of Breast Pathology; Seattle, WA |
| 2010 | 100 Young Scientists in the World Travel Award, The 1st São Paulo School of Translational Sciences Conference at A.C. Camargo Cancer Center; São Paulo, Brazil |
| 2009 | Trainee Excellence Award, The University of Texas MD Anderson Cancer Center; Houston, TX |
| 2008 | Travel Award, Mitochondrial Biology in Cardiovascular Health and Diseases Conference; Baltimore, MD |
| 1999 | Outstanding Intern Award, Jiangsu Province Hospital; Nanjing, Jiangsu, China |
| 1998 | The 1st Class Scholarship, Nanjing Medical University; Nanjing, Jiangsu, China |
| 1998 | Magna Cum Laude Graduate, Nanjing Medical University; Nanjing, Jiangsu, China |
| 1995 | The 1st Class Scholarship, Nanjing Medical University; Nanjing, Jiangsu, China |
Professional Memberships
Selected Presentations & Talks
Local Presentations
- 2026. Predictive Modeling in Oncology Using EHR and Genomic Data. Invited. Faculty-led program titled “Health Informatics: Global Perspectives”. Houston, Texas, US.
- 2025. Papillary Lesions of the Breast. Invited. Resident Education Meeting. Houston, Texas, US.
- 2025. Deciphering the Genetic Landscape of Invasive Mammary Paget Disease Using Spatial Transcriptomics. Invited. Spatial Proteomics and Transcriptomics Collaborative Workshop. Houston, Texas, US.
- 2023. Reassessing Histopathology of Breast Cancer Cases with Pathologic Complete Response after Neoadjuvant Chemotherapy. Invited. Interview Meeting. Houston, Texas, US.
National Presentations
- 2026. Invasive Lobular Carcinoma: Core Concepts and Emerging Updates. Invited. Pathology Online Education Meetings, US.
- 2022. Recommendations for Pathologic Evaluation of Breast Specimens after Neoadjuvant Therapy and Reassessing Histopathology of Breast Cases with Pathologic Complete Response. Invited. Interview Presentation. Houston, Texas, US.
- 2020. TRPS1: a highly sensitive and specific marker for breast carcinoma. Invited. Interview Presentation. Atlanta, Georgia, US.
International Presentations
- 2025. Loss of Kdm3a Suppresses Skin Basaloid Carcinoma Development in Trp53R172H Mice. Invited. Asian Society of Dermatology Annual Meeting. Bangkok, TH.
- 2024. Testing IMP3 as a Surrogate Immunohistochemical Marker for Thyroid Nodules with THADA Fusion in Both Cytological and Surgical Specimens. Invited. Grand Round. Nanjing, CN.
- 2023. Artificial Intelligence (AI) in Medicine - Perspective from Pathology. Invited. Grand Round. Nanjing, CN.
- 2013. Canonical Wnt Signaling Functions in Second Cardiac Lineage Development. Invited. Grand Round. Haikou, CN.
- 2013. What We Learn from Clinical Trials in Perioperative Medicine. Invited. Grand Round. Haikou, CN.
- 2010. Canonical Wnt Signaling Functions in Second Cardiac Lineage Development. Invited. The 1st São Paulo School of Translational Sciences Conference. São Paulo, BR.
Grant & Contract Support
| Date: | 2026 - 2029 |
| Title: | Investigating how tRNA modifications rewires mRNA translation in breast cancers |
| Funding Source: | US DOD |
| Role: | Co-I |
| Date: | 2026 - 2027 |
| Title: | Targeting of Sstr2 expressing cancer stem cells in triple negative breast cancer |
| Funding Source: | US DOD |
| Role: | Co-I |
| Date: | 2025 - 2025 |
| Title: | Investigating how deregulated tRNA modifications leads to translational reprogramming in cancer |
| Funding Source: | Cancer Prevention & Research Institute of Texas (CPRIT) |
| Role: | PI |
| ID: | RP260225 |
| Date: | 2023 - 2028 |
| Title: | Lactation on Breast Tumorigenesis |
| Funding Source: | NIH/NCI |
| Role: | Co-I |
| ID: | R01 CA2715801A1 |
| Date: | 2008 - 2010 |
| Title: | The platelet-derived growth factor receptor (PDGFR) as an essential component of cardiomyocytes response to stress |
| Funding Source: | American Heart Association (AHA) |
| Role: | PI |
| ID: | 0825014F |
Selected Publications
Peer-Reviewed Articles
- Li, XX, Haw, Y, Liu, Y, Iqbal, J, Ahmed, SS, Guo, H, Wei, S, Yasmeen, S, Ye, J, Hou, Y, Eshraghi, R, Zhang, H, Ai, D, Zhang, G, Nayak, A, Farahani, SJ, Rosa, M, Zhan, H, Buttars, P, Bakkar, R, Schnitt, S, Brogi, E, Allison, K, Collins, LC, Sahin, A, Siziopikou, KP, Chen, YY, Khoury, T. An Agreement Study of Stromal Cellularity, Stromal Cell Atypia, and Tumor Border of Phyllodes Tumors of the Breast. Mod Pathol, 2026. e-Pub 2026. PMID: 42705611.
- Podany P, Zhan H, Colón-Cartagena L, Ai D, Du J, Krishnamurti U, Liang Y. Histomorphologic analysis and clinical correlation of atypical apocrine lesions in breast pathology. Hum Pathol 175, 2026. e-Pub 2026. PMID: 42176994.
- Ai, D, Zhang, Y, Viswanathan, K, Zhang, J, Magliocca, KR, Steward-Tharp, SM, Hsiao, WY, Shi, Q. Testing insulin-like growth factor messenger RNA–binding protein 3 as a surrogate immunohistochemical marker for indeterminate thyroid nodules with THADA fusion in both cytologic and surgical specimens. Cancer Cytopathol 134(3), 2026. e-Pub 2026. PMID: 41748276.
- Korie U, Ai D, Podany P, Zhang H, Zhan HY, Kahila M, Colon-Cartagena L, Wei S, Sun H, Du J, Krishnamurti U, Liang Y. Interobserver Agreement and Histologic Analysis of Atypical Ductal Hyperplasia Bordering on Ductal Carcinoma In Situ, a Multi-institutional Study. Am J Surg Pathol, 2025. e-Pub 2025. PMID: 40994034.
- Podany P, Zhan H, Ai D, Krishnamurti U, Liang Y. Estrogen Receptor Conversion in Bone, Liver and Lung Metastases from Breast Cancer. Pathol Res Pract, 2025. e-Pub 2025. PMID: 40967162.
- Ai D, Ewaz AM, Smaalen KV, Li XX. High Upgrade Rate to Invasive Carcinoma Makes Subclassification of Papillary Carcinoma of the Breast in Core Needle Biopsy Unnecessary. J Clin Pathol 78(11):748-752, 2025. e-Pub 2025. PMID: 40908108.
- Anh Nguyen TT, Zhang J, Iqbal J, Ahmed SS, Liu Y, Yang L, Zhang G, Ning B, Guo H, Wei S, Hou Y, Agarwal I, Yasmeen S, Khoury T, Ai D, Deng H, Liu Y, Peng L, Chen YY, Siziopikou KP, Li X. Proposing New Criteria for Classification of Benign Fibroepithelial Lesions Based on Clinicopathologic Evaluations of 507 Cases with Clinical Outcome. Mod Pathol 38(10):100812, 2025. e-Pub 2025. PMID: 40516609.
- Ai D, Arrey EN, Postlewait LM, Gao Y, Li X. The prevalence and clinical significance of residual occult breast cancer after neoadjuvant chemotherapy: reassessing surgical pathology in cases initially described as pathological complete response. Histopathology 86(7):1112-1120, 2025. e-Pub 2025. PMID: 39904575.
- Assaye T, Abunimer L, Calisi N, Ai D. Breast Hemangioma Diagnosed in a Male Patient: A Case Report. Cureus 17(2):e78390, 2025. e-Pub 2025. PMID: 40046370.
- Turashvili G, Gao Y, Ai D, Ewaz AM, Gjeorgjievski SG, Wang Q, Nguyen TTA, Zhang C, Li X. Low interobserver agreement among subspecialised breast pathologists in evaluating HER2-low breast cancer. J Clin Pathol 77(12):815-821, 2024. e-Pub 2024. PMID: 37714693.
- Rehman, AU, Rolle, NA, Ghleilib, I, Ai, D. Adenoid cystic carcinoma in situ of the breast - A case report. Hum Pathol Rep 37, 2024. e-Pub 2024.
- Ai D, Turashvili G, Gjeorgjievski SG, Wang Q, Ewaz AM, Gao Y, Nguyen T, Zhang C, Li X. Subspecialized breast pathologists have suboptimal interobserver agreement in Ki-67 evaluation using 20% as the cutoff. Breast Cancer Res Treat 204(2):415-422, 2024. e-Pub 2024. PMID: 38157098.
- Liao Y, Xiang Y, Zhao Z, Ai D. Bayesian mixed-effect higher-order hidden Markov models with applications to predictive healthcare using electronic health records. IISE Trans 57(2):186-198, 2024. e-Pub 2024.
- Turashvili G, Gjeorgjievski SG, Wang Q, Ewaz A, Ai D, Li X, Badve SS. Intraoperative assessment of axillary sentinel lymph nodes by telepathology. Breast Cancer Res Treat 202(3):423-434, 2023. e-Pub 2023. PMID: 37688667.
- Zhao HC, Ni P, Zhao Q, Liang X, Ai, D, Erhardt S, Wang J, Li Y, Wang JX. Identifying the serious clinical outcomes of adverse reactions to drugs by a multi-task deep learning framework. Commun Biol 6(1):870, 2023. e-Pub 2023. PMID: 37620651.
- Hu S, Alpert L, M Cates JM, Gonzalez RS, Graham R, Goldblum JR, Bakhshwin A, Shetty S, Wang HL, Lollie T, Ma C, Siddique A, Karamchandani DM, Chen F, Yantiss RK, Hissong E, Chatterjee D, Chopra S, Chen W, Vazzano J, Wang W, Ai D, Lin J, Zheng L, Davis JL, Brinkerhoff B, Breitbarth A, Yang M, Madahian S, Panarelli N, Kuan K, Pomper J, Longacre T, Raghavan S, Misdraji J, Cui M, Yang Z, Savant D, Harpaz N, Chen X, Resnick M, Wu EY, Klimstra D, Shia J, Vyas M, Kakar S, Choi W, Robert ME, Li H, Lee M, Clark I, Li Y, Cao W, Chang Q, Bronner MP, Dong Z, Zhang W, Buehler D, Swanson PE, Mantilla JG, Bellizzi AM, Feely M, Cooper HS, Nagarathinam R, Pai R, Hammer S, Hosseini M, Hu J, Westerhoff M, Cheng J, Agostini-Vulaj D, Lauwers G, Ghayouri M, Pezhouh MK, Zeng J, Xia R, Yin F, Zhang T, Gao Z, Demko N, Chen HH, Yu S, Hart J. Gastrointestinal stromal tumors (GISTs) arising in uncommon locations: clinicopathologic features and risk assessment of esophageal, colonic, and appendiceal GISTs. Mod Pathol 4(35):554-563, 2022. e-Pub 2022. PMID: 34702994.
- Zheng M, Erhardt S, Ai D, Wang J. Bmp Signaling Regulates Hand1 in a Dose-Dependent Manner during Heart Development. Int J Mol Sci 22(18), 2021. e-Pub 2021. PMID: 34576009.
- Ai D, Yao J, Yang F, Huo L, Chen H, Lu W, Soto LMS, Jiang M, Raso MG, Wang S, Bell D, Liu J, Wang H, Tan D, Torres-Cabala C, Gan Q, Wu Y, Albarracin C, Hung MC, Meric-Bernstam F, Wistuba II, Prieto VG, Sahin AA, Ding Q. TRPS1: a highly sensitive and specific marker for breast carcinoma, especially for triple-negative breast cancer. Mod Pathol 34(4):710-719, 2021. e-Pub 2021. PMID: 33011748.
- Ai D, Zreik RT, Harris FS, Hill G, Shan Y. Primary epithelioid angiosarcoma of the temporal bone with initial presentation of otalgia. Proc (Bayl Univ Med Cent) 31(1):84-87, 2017. e-Pub 2017. PMID: 29686564.
- Cata JP, Ramirez MF, Velasquez JF, Ai D, Popat KU, Gottumukkala V, Black DM, Lewis VO, Vauthey JN. Lidocaine Stimulates the Function of Natural Killer Cells in Different Experimental Settings. Anticancer Res 37(9):4727-4732, 2017. e-Pub 2017. PMID: 28870891.
- Konda P, Ai D, Guerra CE, Rodriguez-Restrepo A, Mehran RJ, Rice D, Hofstetter W, Heir J, Kwater P, Gottumukkala V, Hernandez M, Cata JP. Identification of Risk Factors Associated With Postoperative Acute Kidney Injury After Esophagectomy for Esophageal Cancer. J Cardiothorac Vasc Anesth 31(2):474-481, 2017. e-Pub 2017. PMID: 27720491.
- Ai D, Cortes JE, Lin P, Khoury JD, Ai D, Tang Z, Tang G, Jorgensen JL, Medeiros JL, Hu S. Impact of trisomy 8 on treatment response and survival of patients with chronic myelogenous leukemia in the era of tyrosine kinase inhibitors. Leukemia 29(11):2263-6, 2015. e-Pub 2015. PMID: 25931274.
- Ai D, Liu W, Lu G, Patel KP, Chen Z. Extramedullary blast crisis as initial presentation in chronic myeloid leukemia with the e1a2 BCR-ABL1 transcript: A case report. Mol Clin Oncol 3(6):1319-1322, 2015. e-Pub 2015. PMID: 26807241.
- Wang, W, Cortes, JE, Lin, P, Beaty, MW, Ai, D, Amin, HM, Ok, CY, Kantarjian, HM, Medeiros, LJ, Hu, S. Clinical and prognostic significance of 3q26.2 and other chromosome 3 abnormalities in CML in the era of tyrosine kinase inhibitors=. Blood, 2015. e-Pub 2015. PMID: 26243778.
- Velásquez FJ, Ramírez MF, Ai D, Lewis V, Cata JP. Impaired Immune Function in Patients Undergoing Surgery for Bone Cancer. Anticancer Res 35(10):5361-6, 2015. e-Pub 2015. PMID: 26408709.
- Ai D, Lasala J, Mehran JR, Xu G, Banchs J, Cata JP. Preoperative Echocardiographic Parameters of Diastolic Dysfunction Did Not Provide a Predictive Value for Postoperative Atrial Fibrillation in Lung and Esophageal Cancer Surgery. J Cardiothorac Vasc Anesth 29(5):1127-30, 2015. e-Pub 2015. PMID: 25976602.
- Wang W, Tang G, Cortes JE, Liu H, Ai D, Yin CC, Li S, Khoury JD, Bueso-Ramos C, Medeiros LJ, Hu S. Chromosomal rearrangement involving 11q23 locus in chronic myelogenous leukemia: a rare phenomenon frequently associated with disease progression and poor prognosis. J Hematol Oncol 8:32, 2015. e-Pub 2015. PMID: 25888368.
- Ai, D, Xu, G, Feng, L, Yu, J, Banchs, J, Vaporciyan, AA, Cata, JP. Dexmedetomidine does not reduce atrial fibrillation after lung cancer surgery. J Cardiothorac Vasc anesth, 2015. e-Pub 2015. PMID: 25440618.
- Ai D, Xu G, Feng L, Yu J, Banchs J, Vaporciyan AA, Cata JP. Dexmedetomidine does not reduce atrial fibrillation after lung cancer surgery. International Anesthesia Research Society 29(2):396-401, 2015. e-Pub 2015. PMID: 25440618.
- Ramirez MF, Ai D, Bauer M, Vauthey JN, Gottumukkala V, Kee S, Shon D, Truty M, Kuerer HM, Kurz A, Hernandez M, Cata JP. Innate immune function after breast, lung, and colorectal cancer surgery. J Surg Res 194(1):185-93, 2015. e-Pub 2015. PMID: 25475022.
- Ai D, Feng L, Yu J, Mehran R, Hoffstetter W, Lasala J, Cata JP. Dexmedetomidine does not reduce atrial fibrillation after esophageal cancer surgery. International Anesthesia Research Society 29(2):396-401, 2014. e-Pub 2014. PMID: 25440618.
- Zhang J, Chintalgattu V, Shih T, Ai D, Xia Y, Khakoo AY. MicroRNA-9 is an activation-induced regulator of PDGFR-beta expression in cardiomyocytes. J Mol Cell Cardiol 51(3):337-46, 2011. e-Pub 2011. PMID: 21684288.
- Chintalgattu, V, Ai, D, Langley, RR, Zhang, J, Bankson, JA, Shih, TL, Reddy, AK, Coombes, KR, Daher, IN, Rati, S, Patel, SS, Pocius, JS, Taffet, GE, Buja, LM, Entman, ML, Khakoo, AY. Cardiomyocyte PDGFR-beta signaling is an essential component of the mouse cardiac response to load-induced stress. J Clin invest 120(2):472-84, 2010. e-Pub 2010. PMID: 20071776.
- Chintalgattu V, Ai D, Langley RR, Zhang J, Bankson JA, Shih TL, Reddy AK, Coombes KR, Daher IN, Pati S, Patel SS, Pocius JS, Taffet GE, Buja LM, Entman ML, Khakoo AY. Cardiomyocyte PDGFR-beta signaling is an essential component of the mouse cardiac response to load-induced stress. Mitochondrial Biology in Cardiovascular Health and Diseases Conference 120(2):472-84, 2008. e-Pub 2008.
- Weng J, Luo J, Cheng X, Jin C, Zhou X, Qu J, Tu L, Ai D, Li D, Wang J, Martin JF, Amendt BA, Liu M. Deletion of G protein-coupled receptor 48 leads to ocular anterior segment dysgenesis (ASD) through down-regulation of Pitx2. Proc Natl Acad Sci U S A 105(16):6081-6, 2008. e-Pub 2008. PMID: 18424556.
- Ai D, Wang J, Amen M, Lu MF, Amendt BA, Martin JF. Nuclear factor 1 and T-cell factor/LEF recognition elements regulate Pitx2 transcription in pituitary development. Mol Cell Biol 27(16):5765-75, 2007. e-Pub 2007. PMID: 17562863.
- Ai, D, Xueyao Fu, Wang, J, Lu, MF, Chen, L, Baldini, A, Klein, WH, Martin, JF. Canonical Wnt signaling functions in second heart field to promote right ventricular growth. Proc Natl Acad Sci USA, 2007. e-Pub 2007. PMID: 17519332.
- Dong F, Sun X, Liu W, Ai D, Klysik E, Lu MF, Hadley J, Antoni L, Chen L, Baldini A, Francis-West P, Martin JF. Pitx2 promotes development of splanchnic mesoderm-derived branchiomeric muscle. Development 133(24):4891-9, 2006. e-Pub 2006. PMID: 17107996.
- Ai, D, Liu, W, Ma, L, Dong FY, Lu, MF, Wang, DG, Verzi, MP, Cai, CL, Gage, PJ, Evans, S, Black, BL, Brown, NA, Martin, JF. Pitx2 regulates cardiac left-right asymmetry by patterning second cardiac lineage-derived myocardium. Dev biol 296(2):437-49, 2006. e-Pub 2006. PMID: 16836994.
Review Articles
- Yi QY, Zhang J, Ai D. Antimicrobial Effects of Essential Oils on Pseudomonas Aeruginosa. J Pathol Res Rev Rep 4(4):1-6, 2022. e-Pub 2022.
- Ai D, Sweeney K, Li X. Short review of malignant adenomyoepithelioma of the breast. Hum Pathol Rep 27, 2022. e-Pub 2022.
- Chen Z, Ai D. Cardiotoxicity associated with targeted cancer therapies. Mol Clin Oncol 4(5):675-681, 2016. e-Pub 2016. PMID: 27123262.
- Ai D, Banchs J, Owusu-Agyemang P, Cata JP. Chemotherapy-induced cardiovascular toxicity: beyond anthracyclines. Minerva Anestesiol, 2014. e-Pub 2014. PMID: 24122036.
Abstracts
- Ai D, Wu Y, Resetkova E. Reporting Morphologic Subtypes of Invasive Lobular Carcinoma (ILC) on Core Needle Biopsy (CNB). 38th European Congress of Pathology. e-Pub 2026.
- Xu H, Petersen S, Saluja K, Liang Y, Sun H, Zhou X, Guo T, Ai D. Distinct Developmental Origins of Invasive Mammary Paget Disease and Invasive Ductal Carcinoma Uncovered by Spatial Transcriptomics. United States and Canadian Academy of Pathology Annual Meeting, 2026. e-Pub 2026.
- Raval P, Ding Q, Singh P, Alrohaibani A, Sun H, Ai D, Wanis K, Zhao M, Chen H, Valero V, Mac Gregor MC, Sahin A. HER2 Status Conversion in Residual Breast Carcinoma After Neoadjuvant HER2-Targeted Therapy in Patients with HER2-Positive Breast Cancer. United States and Canadian Academy of Pathology Annual Meeting, 2026. e-Pub 2026.
- Perera N, Zhan H, Ai D, Du J, Krishnamurti U, Liang Y. Can Histologic Features of Flat Epithelial Atypia Distinguish Cases with and without Co-Existing Ductal Carcinoma In Situ (DCIS)?. United States and Canadian Academy of Pathology Annual Meeting, 2026. e-Pub 2026.
- Salehiazar S, Moideen P, Zhan H, Ai D, Krishnamurti U, Liang Y. Estimating Breast Tumor Size from Histologic Section Involvement: A Correlative Study with Imaging and Gross Pathology. United States and Canadian Academy of Pathology Annual Meeting, 2026. e-Pub 2026.
- Al-Refai R, Perrier A, Ding Q, Huang X, Sun H, Ai D, Hunt K, Aysegul Sahin HL. Clinicopathologic Features and Outcomes of Phyllodes Tumors in Women Under 40 Years: A Single-Institution Cohort of 286 Cases. United States and Canadian Academy of Pathology Annual Meeting, 2026. e-Pub 2026.
- Li XX, Haw Y, Liu Y, Iqbal J, Ahmed SS, Guo H, Wei S, Yasmeen S, Ye J, Hou YJ, Eshraghi R, Zhang H, Ai D, Zhang G, Nayak A, Farahani SJ, Marilin R, Zhan HY, Buttars P, Bakkar R, Schnitt S, Brogi E, Allison K, Collins LC, Sahin A, Siziopikou KP, Chen YY, Khoury T. An Agreement Study of Stromal Cellularity and Stromal Cell Atypia, and Tumor Border of Fibroepithelial Lesions of the Breast. United States and Canadian Academy of Pathology Annual Meeting, 2026. e-Pub 2026.
- Xu H, Raval P, Peterson S, Saluja K, Liang YX, Sun H, Zhou X, Guo TH, Ai D. Distinct Developmental Origins of Invasive Mammary Paget Disease and Invasive Ductal Carcinoma Uncovered by Spatial Transcriptomics. Texas Society of Pathologists, 2026. e-Pub 2026.
- Xu A, Zhao R, Xu J, Cho WC, Lee D, Ai D. Loss of Kdm3a Suppresses Basaloid Carcinoma Development in p53-R172H Mice. Asian Society of Dermatopathology 2025, 2025. e-Pub 2025.
- Xu A, Zhao RY, Xu JM, Cho WC, Lee DF, Ai D. Loss of Kdm3a Suppresses Basaloid Carcinoma Development in p53-R172H Mice. The 14th Asia Pacific International Academy of Pathology Congress, 2025. e-Pub 2025.
- Rehman AU, Tandon N, Guo TH, Ai D. Bilateral mixed fibroadenoma and tubular adenoma, a rare case report. The American Society for Clinical Pathology, 2025. e-Pub 2025.
- Nguyen T, Zhang J, Iqbal J, Liu Y, Yang LL, Zhang G, Guo H, Wei S, Hou Y, Agarwal I, Siziopikou KP, Yasmeen S, Thaer K, Ai D, Deng HY, Liu Y, Peng LM, Chen YY, Li X. Clinicopathologic evaluations of 500 cellular fibroadenoma, benign and borderline phyllodes tumors indicate the current classification may not have clinical implications. United States and Canadian Academy of Pathology Annual Meeting, 2025. e-Pub 2025.
- Gite S, Amin S, Tanwar P, Saluja L, Mahmoud E, Liu J, Ai D. Sinonasal Squamous Cell Carcinoma with DEK::AFF2 Fusion: A Rare Entity Mimicking Benign Sinonasal Papilloma, Posing a Diagnostic Conundrum. Texas Society of Pathologists, 2025. e-Pub 2025.
- Tanwar P, Ai D, Ogbureke KVigneswaran N, Covinsky M. Adenoid Ameloblastoma or a hybrid cystic ameloblastoma-adenomatoid odontogenic tumor?: a case report. Texas Society of Pathologists, 2025. e-Pub 2025.
- Ur Rehman A, Tandon N, Guo T, Ai D. Bilateral mixed fibroadenoma and tubular adenoma, a rare case report. Texas Society of Pathologists, 2025. e-Pub 2025.
- Ali M, Lubin D, Viswanathan K, Ai D, Shi Q. Reclassification of Thyroid Neoplasms with Aid of Genetic Alterations and Their Surrogate Markers. ASC 72nd Annual Scientific Meeting, 2024. e-Pub 2024.
- Naik UK, Khalid MH, Li R, Saluja K, Ai D. A Rare Presentation of Primary Amyloidosis with Osseous Metaplasia involving Bilateral Breasts, Radiologically Mimicking as Fibroepithelial Neoplasm. Texas Society of Pathologists Summer Retreat and Young Physician Conference, 2024. e-Pub 2024.
- Erem AS, Ai D, Birdsong GG, Wolner Z, Bellizzi AM, Douglas P. Utility of Immunohistochemistry in the Diagnosis of Porocarcinoma and Other Cutaneous Neoplasms. United States and Canadian Academy of Pathology Annual Meeting, 2024. e-Pub 2024.
- Ai D, Visvanathan K, Hsiao WY, Steward-Tharp S, Zhang JL, Magliocca K, Shi QY. IMP3 as a Surrogate Immunohistochemical Marker for Thyroid Nodules with THADA Fusion in Cytological and Surgical Specimens. United States and Canadian Academy of Pathology Annual Meeting, 2024. e-Pub 2024.
- Ai D, Postlewait LM, Gao Y, Li XX. Occult Carcinoma in Deeper Sections of HER2 Positive Breast Cancer Cases with Pathologic Complete Response after Neoadjuvant Therapy is not Associated with Worse Outcomes. United States and Canadian Academy of Pathology Annual Meeting, 2024. e-Pub 2024.
- Mahdi Z, Liu XY, Ai D, Shi QY. Cytology-Histology Correlation for Indeterminate Thyroid Nodules Harboring PAX8 or NTRK Gene Fusions. United States and Canadian Academy of Pathology Annual Meeting, 2023. e-Pub 2023.
- Mahdi Z, Steward-Tharp SM, Ai D, Lubin D, Shi, QY, Saeed F, Viswanathan K, Magliocca KR. Sclerosis, Ossification, Tyrosine crystals: Unusual and Rare Histopathological Features in Salivary Adenoid Cystic Carcinoma. United States and Canadian Academy of Pathology Annual Meeting, 2023. e-Pub 2023.
- Dent EA, Chen J, Ai D, Lee JH, Nguyen T, Turashvili G, Li X. Atypical Ductal Hyperplasia of the Breast: Morphologic Variables Have a Limited Value in Predicting Upgrade Rate in Subsequent Surgical Specimens. United States and Canadian Academy of Pathology Annual Meeting, 2023. e-Pub 2023.
- Ai D, Postlewait LM, Gao Y, Li X. Reassessing Histopathology of Breast Cancer Cases with Pathologic Complete Response after Neoadjuvant Therapy. United States and Canadian Academy of Pathology Annual Meeting, 2023. e-Pub 2023.
- Li X, Gao Y, Ai D, Ewaz AM, Gjorgova Gjeorgjievski S, Wang Q, Nguyen T, Zhang C, Turashvili G. Subspecialized Breast Pathologists have Moderate Interobserver Agreement in Ki-67 Evaluation Using 20% as the Cutoff. United States and Canadian Academy of Pathology Annual Meeting, 2023. e-Pub 2023.
- Turashvili G, Gjorgova Gjeorgjievski S, Wang Q, Ewaz AM, Ai D, Li X, Badve SS. Intraoperative Assessment of Axillary Sentinel Lymph Nodes by Telepathology. United States and Canadian Academy of Pathology Annual Meeting, 2023. e-Pub 2023.
- Steward-Tharp S, Ponnatt TS, Magliocca K, Lubin D, Mahdi Z, Saeed F, Viswanathan K, Ai D, Shi QY. Surveying for Therapeutic Targets in Poorly Differentiated Carcinoma in the Sinonasal Tract: Immunohistochemical assessment of IDH2, SSTR2A, and CXCR4 in Tumors with Neuroendocrine Features. United States and Canadian Academy of Pathology Annual Meeting, 2022. e-Pub 2022.
- Ai D, Sweeny K, Chen H, Alberracin C. ER-/PR+ Breast Cancer Cases Across Two FDA-Approved Platforms: Incidence and Clinicopathologic Correlates. United States and Canadian Academy of Pathology Annual Meeting, 2021. e-Pub 2021.
- Ai D, Francois J, Wang J, Rao A. Canonical WNT and HIPPO Pathways in Triple Negative Breast Cancer. The College of American Pathologists Annual Meeting, 2018. e-Pub 2018.
- Jebakumar D, Ai D, Guillory B, He J, Walker K, Rao A. Gene Expression Analysis of Immune Response in Triple Negative Breast Carcinomas among Different Ethnic Groups. United States and Canadian Academy of Pathology Annual Meeting, 2017. e-Pub 2017.
- Ai D, Jebakumar D, McCormick-Baw C, Zhou S, Wu EX, Baker J, Liu L, Rao A. PITX2 Expression is Elevated in a Progressive Manner in Breast Papilloma and Triple-negative Breast Carcinoma. United States and Canadian Academy of Pathology Annual Meeting, 2017. e-Pub 2017.
- Ai D, Leng B, Walker K, Hendrickson S, Werlang-Perurena A, Rao A. A high-throughput methodology identifies GATA-3 expression is closely associated with ER IHC level in invasive ductal carcinoma. United States and Canadian Academy of Pathology Annual Meeting, 2016. e-Pub 2016.
- Ai D, Lasala J, Banchs J, Cata J. Echocardiography Did Not Provide A Predictive Value For Postoperative Atrial Fibrillation In Lung And Esophageal Cancer Surgery. Society of Cardiovascular Anesthesiologists Annual Meeting, 2015. e-Pub 2015.
- Rich A, Ai D, Wang W, You J, Yin CC, Bueso-Ramos CE, Medeiros JL, Hu SM. Pediatric chronic myelogenous leukemia in tyrosine kinase inhibitor era. The United States and Canadian Academy of Pathology. e-Pub 2015.
- Wang W, Ai D, Tang GL, Liu H, Bueso-Ramos CE, Medeiros JL, Hu SM. Balanced 11q23/MLL rearrangement in chronic myelogenous leukemia. United States and Canadian Academy of Pathology Annual Meeting, 2015. e-Pub 2015.
- Ai D, Fu X, Wang J, Lu MF, Chen L, Baldini A, Klein WH, Martin JF. Canonical Wnt signaling functions in second heart field to promote right ventricular growth. The 1st São Paulo School of Translational Sciences, 2010. e-Pub 2010.
- Ai D, Fu X, Wang J, Lu MF, Chen L, Baldini A, Klein WH, Martin JF. Canonical Wnt signaling functions in second heart field to promote right ventricular growth. The 13th Annual Weinstein Cardiovascular Conference, 2007. e-Pub 2007. PMID: 17519332.
- Ai D, Fu X, Wang J, Lu MF, Chen L, Baldini A, Klein WH, Martin JF. Canonical Wnt signaling functions in second heart field to promote right ventricular growth. Cardiovascular Research Institute Annual Conference, 2006. e-Pub 2006. PMID: 17519332.
- Ai D, Liu W, Ma L, Dong F, Lu MF, Wang D, Verzi MP, Cai C, Gage PJ, Evans S, Black BL, Brown NA, Martin JF. Pitx2 regulates cardiac left-right asymmetry by patterning second cardiac lineage-derived myocardium. The 12th Annual Weinstein Cardiovascular Conference, 2005. e-Pub 2005. PMID: 16836994.
Book Chapters
- Shan Y, Wu HW, Zhang DR, Ai D, Zreik R, Huang H. Soft Tissue Tumors, Molecular Diagnosis and Pathology. In: Advances in Soft Tissue Tumors, 2022.
- Ai D, Cata JP. Atrial Fibrillation After Surgery. In: General Surgery: Principles, Practice and Postoperative Complications, 2014.
Web Publications
- Kakarala B, Reisenbichler ES, Ai D. Breast Sarcoma, 2026.
- Javadi T, Ai D. Benign breast implant related changes, 2023.
- Ai D, Ding QQ. TRPS1, 2022.
Patient Reviews
CV information above last modified September 21, 2026