Di Zhao, Ph.D.
Department of Experimental Radiation Oncology, Division of Radiation Oncology
About Dr. Di Zhao
Dr. Di Zhao earned her Ph.D. in Biochemistry and Molecular Biology from Fudan University in Shanghai, China, with a major research focus on cancer metabolism ( Zhao et al. Cancer Cell 2013, and Zhao et al. J Clin. Invest . 2014 ). Then, Dr. Zhao started her postdoctoral training under Dr. Ronald DePinho at the University of Texas MD Anderson Cancer Center in the Department of Cancer Biology. Her highly productive postdoctoral research focused on prostate cancer genetics and biology ( Zhao et al. Nature 2017, and Zhao et al. Cancer Discovery 2020 ). In 2019, Dr. Zhao started her independent laboratory in the Department of Experimental Radiation Oncology at MD Anderson. Her research focuses on functional cancer genomics, with a special interest in advanced prostate cancer. Combining state-of-the-art genetically engineered mouse modeling systems and single-cell multi-omics, her team has successfully characterized several genetic determinants that drive prostate cancer progression, tumor microenvironment remodeling, and resistance to therapies. Some of these studies have been recently published in high-profile journals, in which Dr. Zhao is the corresponding author ( Shi et al. Sci Transl Med 2023; Li et al. Cancer Res 2022 ). Dr. Zhao has been awarded a variety of fellowships and awards, including NIH/NCI Pathway to Independence Award (K99/R00) (2018), CPRIT Recruitment of First-Time Tenure-Track Faculty Award (2019), NIH NCI R01 (2023), Prostate Cancer Foundation Challenge Award (2023), DoD Prostate Cancer Research Program Idea Development Award (2024), and among others.
Present Title & Affiliation
Primary Appointment
Assistant Professor, Department of Experimental Radiation Oncology, Division of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX
Dual/Joint/Adjunct Appointment
Assistant Professor, Department of Experimental Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX
Research Interests
Over the past decade, large-scale cancer genome studies have uncovered emerging genetic alterations in malignancies. Research in my laboratory focuses on functional cancer genomics, with a special interest in advanced prostate cancer. Combining the state-of-the-art mouse modeling systems and single-cell multi-omics, we aim to 1) characterize the genetic determinants that drive prostate cancer development, metastatic progression, and therapy resistance; 2) determine the impact of cancer genome on the tumor immune microenvironment and responsiveness to immunotherapies; 3) develop biomarker-driven therapies and combinatorial strategies for personalized cancer medicine.
Education & Training
Degree-Granting Education
| 2014 | Fudan University, Shanghai, CN, Biochemistry & Molecular Biology, Ph.D |
| 2009 | Zhejiang University, Hangzhou, CN, Biotechnology, BS |
Postgraduate Training
| 2016-2019 | Odyssey Fellow, Prostate Cancer Biology, UT MD Anderson Cancer Center, Houston, Texas |
| 2014-2019 | Postdoctoral Fellowship, Prostate Cancer Biology, UT MD Anderson Cancer Center, Houston, Texas |
Experience & Service
Institutional Committee Activities
Chair, Javier Leo's advisory committee, 2023 - Present
Member, GSBS Scholarship and Fellowship Committee, 2023 - 2026
Member, Zhouyihan (Aileen) Li's advisory committee, 2023 - Present
Chair, Odyssey Program Committee, 2022 - 2023
Member, CPRIT Graduate Scholar Review Committee, 2022 - 2024
Member, Mary E. Fuentes's advisory committee, 2022 - 2023
Member, Odyssey Program Committee, 2020 - 2023
Member, Xiaojie Yang's advisory committee, 2020 - 2023
Member, ROSI Scientific Review Committee, 2020 - 2023
Honors & Awards
| Ray Wu Prize, Ray Wu Memorial Foundation | |
| Odyssey Fellowship, UT MD Anderson Cancer Center | |
| The Lupe C. Garcia Fellowship in Cancer Research, UT MD Anderson Cancer Center | |
| Prostate Cancer Foundation Young Investigator Award, Prostate Cancer Foundation | |
| NCI Pathway to Independence Award (K99/R00), NIH | |
| FY18 Postdoctoral Travel Awards, UT MD Anderson Cancer Center | |
| UT System Rising STARs Award, University of Texas | |
| CPRIT Recruitment of First-Time Tenure-Track Faculty Award, CPRIT | |
| Prostate Cancer SPORE Career Enhancement Program Award, MDACC | |
| Prostate Cancer Foundation Challenge Award, Prostate Cancer Foundation | |
| Faculty Scholar Award, UT MD Anderson Cancer Center | |
| Serican Academy of Urology Rising Star Award, Serican Academy of Urology | |
| DoD Prostate Cancer Research Program Idea Development Award, DoD | |
| AACR Annual Meeting 2025 NextGen Star, AACR |
Selected Publications
Peer-Reviewed Articles
- Teng H, Hang Q, Zheng C, Yan Y, Zhao Y, Deng Y, Nie L, Wu W, Sheldon M, Yu Z, Shi W, Gao J, Meng C, Martinez C, Zhang J, Yao F, Sun Y, Zhao D, Chen J, Gan B, Meng T, Ma L. In vivo CRISPR activation screen identifies a driver and therapeutic vulnerability of bone metastasis. Science Translational Medicine None(None):None. e-Pub 2024. PMID: None.
- Meng C, Lin K, Shi W, Teng H, DeBruine A, Wang Y, Chen F, Leo J, Zhang J, Van V, Maldonado K, Gan B, Ma L, Lu Y, Zhao D. Histone Methyltransferase ASH1L Primes Metastases and Metabolic Reprogramming of Macrophages in the Bone Niche. Nature Communications None(None):None. e-Pub 2024. PMID: None.
- Chen F, Li H, Wang Y, Tang X, Lin K, Li Q, Meng C, Shi W, Leo J, Liang X, Zhang J, Van V, Mahmud I, Wei B, Lorenzi P, Raso M, Aparicio A, Lu Y, Frigo D, Gan B, Zhao D. CHD1 Loss Hijacks SREBP2-mediated Cholesterol Biosynthesis to Fuel SPOP-deficient Prostate Cancer and Confers Resistance to Castration. Nature Cancer None(None):None. e-Pub 2024. PMID: None.
- Shi W, Wang Y, Zhao Y, Kim JJ, Li H, Meng C, Chen F, Zhang J, Mak DH, Van V, Leo J, St Croix B, Aparicio A, Zhao D. Immune Checkpoint B7-H3 is a Therapeutic Vulnerability in Prostate Cancer Harboring PTEN and TP53 Deficiencies. Sci Transl Med 15(695):eadf6724, 2023. e-Pub 2023. PMID: 37163614.
- Li H, Wang Y, Lin K, Venkadakrishnan VB, Bakht M, Shi W, Meng C, Zhang J, Tremble K, Liang X, Song JH, Feng X, Van V, Deng P, Burks JK, Aparicio A, Keyomarsi K, Chen J, Lu Y, Beltran H, Zhao D. CHD1 promotes sensitivity to Aurora kinase inhibitors by suppressing interaction of AURKA with its coactivator TPX2. Cancer Res 82(17):3088-3101, 2022. e-Pub 2022. PMID: 35771632.
- Wang Y, Abe J, Chau K, Wang Y, Vu H, Velatooru L, Gulraiz F, Imanishi M, Samanthapudi V, Nguyen M, Ko K, Lee L, Thomas T, Olmsted-Davis E, Kotla S, Fujiwara K, Cooke J, Zhao D, Evans S, Le N. MAGI1 inhibits interferon signaling to promote influenza A infection. Frontiers in Cardiovascular Medicine 9, 2022. e-Pub 2022. PMID: 36082118.
- Lee R, Li J, Li J, Wu CJ, Jiang S, Hsu WH, Chakravarti D, Chen P, LaBella KA, Li J, Spring DJ, Zhao D, Wang YA, DePinho RA. Synthetic Essentiality of Tryptophan 2, 3-dioxygenase 2 in APC-Mutated Colorectal Cancer. Cancer Discov 12(7):1702-1717, 2022. e-Pub 2022. PMID: 35537038.
- Deng Y, Xia X, Zhao Y, Zhao Z, Martinez C, Yin W, Yao J, Hang Q, Wu W, Zhang J, Yu Y, Xia W, Yao F, Zhao D, Sun Y, Ying H, Hung MC, Ma L. Glucocorticoid receptor regulates PD-L1 and MHC-I in pancreatic cancer cells to promote immune evasion and immunotherapy resistance. Nat Commun 12(1):7041, 2021. e-Pub 2021. PMID: 34873175.
- Chakravarti D, Hu B, Mao X, Rashid A, Li J, Li J, Liao WT, Whitley EM, Dey P, Hou P, LaBella KA, Chang A, Wang G, Spring DJ, Deng P, Zhao D, Liang X, Lan Z, Lin Y, Sarkar S, Terranova C, Deribe YL, Blutt SE, Okhuysen P, Zhang J, Vilar E, Nielsen OH, Dupont A, Younes M, Patel KR, Shroyer NF, Rai K, Estes MK, Wang YA, Bertuch AA, DePinho RA. Telomere dysfunction activates YAP1 to drive tissue inflammation. Nat Commun 11(1):4766, 2020. e-Pub 2020. PMID: 32958778.
- Zhao D, Cai L, Lu X, Liang X, Li J, Chen P, Ittmann M, Shang X, Jiang S, Li H, Meng C, Flores I, Song JH, Horner JW, Lan Z, Wu CJ, Li J, Chang Q, Chen KC, Wang G, Deng P, Spring DJ, Wang YA, DePinho RA. Chromatin Regulator, CHD1, Remodels the Immunosuppressive Tumor Microenvironment in PTEN-Deficient Prostate Cancer. Cancer Discovery 10(9):None, 2020. e-Pub 2020. PMID: 32385075.
- Chen P, Zhao D, Li J, Liang X, Li J, Chang A, Henry VK, Lan Z, Spring DJ, Rao G, Wang YA, DePinho RA. Symbiotic Macrophage-Glioma Cell Interactions Reveal Synthetic Lethality in PTEN-Null Glioma. Cancer Cell 35(6):868-884.e6, 2019. e-Pub 2019. PMID: 31185211.
- Liao W, Overman MJ, Boutin AT, Shang X, Zhao D, Dey P, Li J, Wang G, Lan Z, Li J, Tang M, Jiang S, Ma X, Chen P, Katkhuda R, Korphaisarn K, Chakravarti D, Chang A, Spring DJ, Chang Q, Zhang J, Maru DM, Maeda DY, Zebala JA, Kopetz S, Wang YA, DePinho RA. KRAS-IRF2 Axis Drives Immune Suppression and Immune Therapy Resistance in Colorectal Cancer. Cancer Cell 35(4):559-572.e7, 2019. e-Pub 2019. PMID: 30905761.
- Lu X, Pan X, Wu CJ, Zhao D, Feng S, Zang Y, Lee R, Khadka S, Amin SB, Jin EJ, Shang X, Deng P, Luo Y, Morgenlander WR, Weinrich J, Lu X, Jiang S, Chang Q, Navone NM, Troncoso P, DePinho RA, Wang YA. An In Vivo Screen Identifies PYGO2 as a Driver for Metastatic Prostate Cancer. Cancer Res 78(14):3823-3833, 2018. e-Pub 2018. PMID: 29769196.
- Zhao D, Lu X, Wang G, Lan Z, Liao W, Li J, Liang X, Chen JR, Shah S, Shang X, Tang M, Deng P, Dey P, Chakravarti D, Chen P, Spring DJ, Navone NM, Troncoso P, Zhang J, Wang YA, DePinho RA. Synthetic essentiality of chromatin remodelling factor CHD1 in PTEN-deficient cancer. Nature 542(7642):484-488, 2017. e-Pub 2017. PMID: 28166537.
- Dey P, Baddour J, Muller F, Wu CC, Wang H, Liao WT, Lan Z, Chen A, Gutschner T, Kang Y, Fleming J, Satani N, Zhao D, Achreja A, Yang L, Lee J, Chang E, Genovese G, Viale A, Ying H, Draetta G, Maitra A, Wang YA, Nagrath D, DePinho RA. Genomic deletion of malic enzyme 2 confers collateral lethality in pancreatic cancer. Nature 542(7639):119-123, 2017. e-Pub 2017. PMID: 28099419.
- Wang G, Lu X, Dey P, Deng P, Wu CC, Jiang S, Fang Z, Zhao K, Konaparthi R, Hua S, Zhang J, Li-Ning-Tapia EM, Kapoor A, Wu CJ, Patel NB, Guo Z, Ramamoorthy V, Tieu TN, Heffernan T, Zhao D, Shang X, Khadka S, Hou P, Hu B, Jin EJ, Yao W, Pan X, Ding Z, Shi Y, Li L, Chang Q, Troncoso P, Logothetis CJ, McArthur MJ, Chin L, Wang YA, DePinho RA. Targeting YAP-Dependent MDSC Infiltration Impairs Tumor Progression. Cancer Discov 6(1):80-95, 2016. e-Pub 2016. PMID: 26701088.
- Zhao D, Mo Y, Li MT, Zou SW, Cheng ZL, Sun YP, Xiong Y, Guan KL, Lei QY. NOTCH-induced aldehyde dehydrogenase 1A1 deacetylation promotes breast cancer stem cells. J Clin Invest 124(12):5453-65, 2014. e-Pub 2014. PMID: 25384215.
- Lv L, Xu YP, Zhao D, Li FL, Wang W, Sasaki N, Jiang Y, Zhou X, Li TT, Guan KL, Lei QY, Xiong Y. Mitogenic and oncogenic stimulation of K433 acetylation promotes PKM2 protein kinase activity and nuclear localization. Mol Cell 52(3):340-52, 2013. e-Pub 2013. PMID: 24120661.
- Zhao D, Xiong Y, Lei QY, Guan KL. LDH-A acetylation: implication in cancer. Oncotarget 4(6):802-3, 2013. e-Pub 2013. PMID: 23868819.
- Zhao D, Zou SW, Liu Y, Zhou X, Mo Y, Wang P, Xu YH, Dong B, Xiong Y, Lei QY, Guan KL. Lysine-5 acetylation negatively regulates lactate dehydrogenase A and is decreased in pancreatic cancer. Cancer Cell 23(4):464-76, 2013. e-Pub 2013. PMID: 23523103.
- Lv L, Li D, Zhao D, Lin R, Chu Y, Zhang H, Zha Z, Liu Y, Li Z, Xu Y, Wang G, Huang Y, Xiong Y, Guan KL, Lei QY. Acetylation targets the M2 isoform of pyruvate kinase for degradation through chaperone-mediated autophagy and promotes tumor growth. Mol Cell 42(6):719-30, 2011. e-Pub 2011. PMID: 21700219.
- Liu CY, Zha ZY, Zhou X, Zhang H, Huang W, Zhao D, Li T, Chan SW, Lim CJ, Hong W, Zhao S, Xiong Y, Lei QY, Guan KL. The hippo tumor pathway promotes TAZ degradation by phosphorylating a phosphodegron and recruiting the SCFbeta-TrCP E3 ligase. J Biol Chem 285(48):37159-69, 2010. e-Pub 2010. PMID: 20858893.
- Chen F, Li H, Wang Y, Tang X, Lin K, Li Q, Meng C, Shi W, Leo J, Liang X, Zhang J, Van V, Mahmud I, Wei B, Lorenzi P, Raso M, Aparicio A, Lu Y, Frigo D, Gan B, Zhao Di. CHD1 loss reprograms SREBP2-driven cholesterol synthesis to fuel androgen-responsive growth and castration resistance in SPOP-mutated prostate tumors. Nature Cancer None(None):None. PMID: None.
Other Articles
- Li H, Gigi L, Zhao D CHD1, a multifaceted epigenetic remodeler in prostate cancer. Front Oncol 13:1123362, 2023. PMID: 36776288.
- Chen, F, Zhong, Z, Zhang, C, Lu, Y, Chan, YT, Wang, N, Zhao, D, Feng, Y Potential Focal Adhesion Kinase Inhibitors in Management of Cancer. International journal of molecular sciences 23(21), 2022. PMID: 36362132.
- Miyahira AK, Zarif JC, Coombs CC, Flavell RR, Russo JW, Zaidi S, Zhao D, Zhao SG, Pienta KJ, Soule HR Prostate cancer research in the 21st century; report from the 2021 Coffey-Holden prostate cancer academy meeting. Prostate 82(2):169-181, 2022. PMID: 34734426.
- Wang G, Zhao D, Spring DJ, DePinho RA Genetics and biology of prostate cancer. Genes Dev 32(17-18):1105-1140, 2018. PMID: 30181359.
- Zhao D, DePinho RA Synthetic essentiality: Targeting tumor suppressor deficiencies in cancer. Bioessays 39(8), 2017. PMID: 28675450.
Editorials
- Mengzhe, G, Shanshan, X, Zhao, D, Shihua, W. Editorial. Frontiers in Endocrinology 13, 2023. PMID: 36866167.
Selected Presentations & Talks
Local Presentations
- 2024. Novel Strategies Targeting Tumor Suppressor Defects in Advanced Prostate Cancer. Invited. Junior Faculty Brainstorm Luncheon. Houston, Texas, US.
- 2024. CHD1, a Multifaceted Epigenetic Remodeler in Prostate Cancer. Invited. GU Gallick meeting. Houston, Texas, US.
- 2023. Targeting B7-H3 in Advanced Prostate Cancer. Invited. GU CCSG Retreat. Houston, Texas, US.
- 2023. Novel Strategies Targeting B7-H3 in Advanced Prostate Cancer. Invited. Gallick Lab Weekly Seminar. Houston, TX, US.
- 2023. Functional Genomics of Prostate Cancer. Invited. MDA Research Townhall Meeting. Houston, TX, US.
- 2022. Targeting B7-H3 in Advanced Prostate Cancer. Invited. Annual Melvin L. Samuels Lectureship. Houston, TX, US.
- 2021. Targeting PTEN and TP53 deficiencies in Advanced Prostate Cancer. Invited. Prostate Cancer Moonshot Meeting. Houston, TX, US.
- 2021. Targeting PTEN and TP53 deficiencies in Advanced Prostate Cancer. Invited. GU Gallick Lab Weekly Seminar. Houston, TX, US.
- 2021. CHD1 in Prostate Cancer. Invited. Translational Research Day. Houston, TX, US.
- 2021. How to apply for CPRIT and other career development awards. Invited. PDAEC CPRIT Seminar. Houston, TX, US.
- 2019. Synthetic Essentiality of CHD1 in Prostate Cancer. Invited. MD Anderson Prostate Cancer Moon Shot Seminar. Houston, TX, US.
- 2018. Synthetic Essentiality of CHD1 in PTEN-deficient Prostate Cancer. Invited. MD Anderson Prostate Cancer Moonshot Seminar. Houston, TX, US.
- 2017. Synthetic Essentiality of CHD1 in PTEN-deficient Prostate Cancer. Invited. Genomic Medicine 1st Annual Science Day. Houston, TX, US.
- 2017. Synthetic Essentiality of CHD1 in PTEN-deficient Prostate Cancer. Invited. Prostate Cancer Moon Shoot Symposium. Houston, TX, US.
National Presentations
- 2024. Identify Genetic Determinants Of Immunotherapy Targeting B7-H3. Poster. Nature Conference-Cancer Immunotherapy. Boston, MA, US.
- 2024. Novel Strategies Targeting Tumor Suppressor Defects in Advanced Prostate Cancer. Invited. PCF Young Investigator Seminar. Zoom, US.
- 2024. Novel Strategies Targeting Tumor Suppressor Defects in Advanced Prostate Cancer. Invited. Invited Visit. Lexington, Kentucky, US.
- 2023. B7-H3 is a Therapeutic Vulnerability in Prostate Cancer Harboring PTEN and TP53 Defects. Poster. 38th SITC Annual Meeting. San Diego, CA, US.
- 2023. Novel Strategies Targeting B7-H3 in Advanced Prostate Cancer. Invited. 8th International Conference on Cancer Research and Drug Development. Boston, MA, US.
- 2023. B7-H3 is a Therapeutic Vulnerability in Prostate Cancer Harboring PTEN and TP53 Defects. Poster. 30th PCF Annual Scientific Retreat. Carlsbad, California, US.
- 2023. Novel Strategies Targeting Tumor Suppressor Defects in Advanced Prostate Cancer. Invited. ACACR Summer Seminar. Zoom, US.
- 2023. Novel Immunotherapy Strategies Targeting PTEN and TP53 defects in Advanced Prostate Cancer. Poster. AACR Advances in Prostate Cancer Research Conference. Denver, CO, US.
- 2022. Novel Immunotherapy Strategies Targeting PTEN and TP53 Defects in Advanced Prostate Cancer. Invited. 13th CBIS Annual meeting. Las Vegas, NV, US.
- 2022. Novel Strategies Targeting Immune Checkpoint B7-H3 in Advanced Prostate Cancer. Poster. 37th SITC Annual Meeting. Boston, MA, US.
- 2022. CHD1 promotes sensitivity to Aurora kinase inhibitors in cancers. Poster. 29th PCF Annual Scientific Retreat. San Diego, CA, US.
- 2022. Novel Strategies Targeting Immune Checkpoint B7-H3 in Advanced Prostate Cancer. Poster. AACR Tumor Immunology and Immunotherapy. Boston, MA, US.
- 2022. CHD1 promotes sensitivity to Aurora kinase inhibitors in cancers. Poster. AACR Special Conference on Cancer Epigenomics. Washington, DC, DC, US.
- 2022. Novel Strategies Targeting Immune Checkpoint B7-H3 in Advanced Prostate Cancer. Invited. 7th International Conference on Cancer Research and Drug Development. Baltimore, MD, US.
- 2020. Synthetic Essentiality in Cancer. Invited. Invited talk. Zoom, US.
- 2019. Chromatin Regulator, CHD1, Remodels Immunosuppressive Tumor Microenvironment in PTEN-Deficient Prostate Cancer. Poster. 26th PCF Annual Scientific Retreat. San Diego, CA, US.
- 2019. Synthetic Essentiality of CHD1 in Prostate Cancer. Invited. NIH Rising Star Lecture Series. Bethesda, MD, US.
- 2019. Synthetic Essentiality of CHD1 in PTEN-deficient Prostate Cancer. Poster. 2019 AACR Annual Meeting. Atlanta, GA, US.
- 2019. The role of epigenetic factor CHD1 in the tumor microenvironment remodeling. Invited. 5th SITC Annual Meeting-Young Investigators’ Forum. Houston, TX, US.
- 2019. Synthetic Essentiality of CHD1 in PTEN-deficient Prostate Cancer. Invited. Invited visit. Chapel Hill, NC, US.
- 2019. Synthetic Essentiality of CHD1 in PTEN-deficient Prostate Cancer. Invited. Invited visit. Chicago, IL, US.
- 2018. Synthetic Essentiality of CHD1 in PTEN-deficient Prostate Cancer. Invited. Invited visit. Seattle, WA, US.
- 2018. Synthetic Essentiality of CHD1 in PTEN-deficient Prostate Cancer. Invited. 25th PCF Annual Scientific Retreat. Carlsbad, CA, US.
- 2018. Synthetic Essentiality of CHD1 in PTEN-deficient Prostate Cancer. Invited. PCF Coffey-Holden Meeting. Los Angeles, CA, US.
- 2018. Synthetic Essentiality of CHD1 in PTEN-deficient Prostate Cancer. Poster. 2018 AACR Annual Meeting. Chicago, IL, US.
- 2017. Synthetic Essentiality of CHD1 in PTEN-deficient Prostate Cancer. Poster. 24th PCF Annual Scientific Retreat. Washington, D.C, DC, US.
International Presentations
- 2024. Identify Genetic Determinants of Immunotherapy Targeting B7-H3. Invited. 2024 International Conference on Life Sciences. Guiyang, CN.
- 2024. How to build a team for grant application as a young investigator. Invited. Women’s Forum of SAU Annual Meeting. Banff, CA.
- 2024. CHD1, a Multifaceted Epigenetic Remodeler in Prostate Cancer. Invited. SAU Annual meeting. Banff, CA.
- 2023. Novel Strategies Targeting Tumor Suppressor Defects in Advanced Prostate Cancer. Invited. Internaltional Molecular Medicine Forum. Zoom, US.
- 2023. Novel Strategies Targeting Tumor Suppressor Defects in Advanced Prostate Cancer. Invited. SAU Annual meeting. Cancun, MX.
- 2023. Novel strategies targeting immune checkpoint B7-H3 in advanced prostate cancer. Poster. CRI-ENCI-AACR International Cancer Immunotherapy Conference. Milano, US.
- 2023. Anticipating Patient Selection Strategies for B7-H3 ADCs in Prostate Cancer. Invited. Daiichi Sankyo-PCF Antibody-Drug Conjugate Scientific Working Group Meeting. Zoom, US.
- 2018. Synthetic Essentiality of CHD1 in Prostate Cancer. Invited. 12th CBIS Biennial Meeting. Shenzhen, CN.
Grant & Contract Support
| Title: | Novel Epigenetic Determinant in Metastatic Prostate Cancer |
| Funding Source: | DoD |
| Role: | PI |
| Title: | Determine the Role of Histone Methyltransferase ASH1L in Metastatic Prostate Cancer |
| Funding Source: | NIH/NCI |
| Role: | PI |
| Title: | Novel Oncogenic Substrate of SPOP Reveals Therapeutic Vulnerability in Metastatic Cancers |
| Funding Source: | UT MD Anderson Cancer Center |
| Role: | PI |
| Title: | Targeting B7-H3 in Aggressive Variant Prostate Cancer |
| Funding Source: | Prostate Cancer Foundation |
| Role: | PI |
| Title: | Novel Approaches Targeting B7-H3 in Castration-resistant Prostate Cancer |
| Funding Source: | NIH/NCI |
| Role: | PI |
| Title: | Explore Novel Therapeutic Targets for Advanced Prostate Cancer Harboring PTEN Loss |
| Funding Source: | Cancer Prevention & Research Institute of Texas (CPRIT) |
| Role: | PI |
| Title: | Determine the Resistance to CDK4/6 Inhibitors in CHD1 Deficient Prostate Cancer |
| Funding Source: | MD Anderson PCa SPORE CEP Award |
| Role: | PI |
| Title: | Novel Oncogenic Substrate of SPOP Reveals Therapeutic Vulnerability in Metastatic Cancers |
| Funding Source: | UT MD Anderson Cancer Center |
| Role: | PI |
| Title: | Novel Therapeutic Approaches Targeting Tumor Suppressor Deficiencies in Prostate Cancer |
| Funding Source: | NIH/NCI |
| Role: | PI |
| Title: | Identification of Novel Function of SPOP Mutations in Prostate Cancer |
| Funding Source: | Prostate Cancer Foundation |
| Role: | PI |
Patient Reviews
CV information above last modified February 20, 2025