Dragan Mirkovic, Ph.D.
Department of Radiation Physics, Division of Radiation Oncology
Present Title & Affiliation
Primary Appointment
Associate Professor, Department of Radiation Physics - Pt Care, Division of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Tx
Associate Member, Department of Medical Physics, The University of Texas Graduate School of Biomedical Sciences, Houston, TX
Dual/Joint/Adjunct Appointment
Associate Professor, Department of Radiation Physics - Patient Care, The University of Texas MD Anderson Cancer Center, Houston, TX
Associate Member, The University of Texas Graduate School of Biomedical Sciences, Houston, TX
Education & Training
Degree-Granting Education
| 1993 | State University of New York at Stony Brook, Stony Brook, New York, US, Ph.D. in Applied Mathematics |
| 1990 | University of Zagreb, Zagreb, HR, M.S. in Nuclear Engineering |
| 1983 | University of Zagreb, Zagreb, HR, BS in Nuclear Engineering |
Postgraduate Training
| 1993-1994 | Postdoctoral Fellowship, Applied Mathematics, State University of New York at Stony Brook, Stony Brook, New York |
Licenses & Certifications
| 2017 | Texas Medical Board |
| 2017 | American Board of Radiology |
| 2005 | Medical Physicist License awarded by the Texas Medical Board |
Experience & Service
Faculty Academic Appointments
Assistant Professor, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, TX, 2005 - 2018
Assistant Professor, Department of Dept. of Computer Science, University of Houston, Houston, TX, 2003 - 2005
Research Faculty, Department of Dept. of Computer Science, University of Houston, Houston, TX, 1998 - 2003
Assistant Professor, Department of Mathematics, Iowa State University, Ames, IA, 1994 - 1999
Postdoctoral Research Associate, Department of Applied Mathematics and Statistics, State University of New York at Stony Brook, Stony Brook, NY, 1993 - 1994
Research/Teaching Assistant, Department of Applied Mathematics and Statistics, State University of New York at Stony Brook, Stony Brook, NY, 1990 - 1993
Visiting Scientist, Department of Nuclear Energy, Brookhaven National Laboratory, Upton, NY, 1989 - 1990
Research Associate, Department of Nuclear Energy, University of Zagreb, Zagreb, 1984 - 1990
Honors & Awards
| 1990 - 1993 | Research Fellowship (Selective), State University of New York Stony Brook |
| 1989 - 1990 | IAEA Fellowship, Brookhaven National Laboratory |
Selected Presentations & Talks
Regional Presentations
- 2000. An Adaptive Software Library for Fast Fourier Transforms, International. Conference. An Adaptive Software Library for Fast Fourier Transforms, International. Sana Fe, NM, US.
- 1997. A Domain Decomposition Algorithm for Random Vibrations, Problems. Conference. A Domain Decomposition Algorithm for Random Vibrations, Problems. Boulder, CO, US.
- 1997. Numerical Solution of the Multidimensional Fokker-Planck Equation With. Conference. Numerical Solution of the Multidimensional Fokker-Planck Equation With. Stanford University, CA, US.
- 1996. A Domain Decomposition Method for the Fokker-Planck Equation. Conference. A Domain Decomposition Method for the Fokker-Planck Equation. Bergen, NO.
- 1996. N-Dimensional Finite Element Package, High Performance Computing. Conference. N-Dimensional Finite Element Package, High Performance Computing. New Orleans, LA, US.
- 1995. Preconditioning for Parallel Domain Decomposition in Mixed Finite Element. Conference. Preconditioning for Parallel Domain Decomposition in Mixed Finite Element. Charlotte, NC, US.
- 1995. Simulations of Porous Media Flow on Parallel Machines. Conference. Simulations of Porous Media Flow on Parallel Machines. Pula, HR.
- 1994. An Efficient Parallel Method for the Porous Media Flow Problem. Conference. An Efficient Parallel Method for the Porous Media Flow Problem. Stony Brook, NY, US.
- 1994. Parallel, Mixed Finite Element Approximation for the Porous Media Flow. Conference. Parallel, Mixed Finite Element Approximation for the Porous Media Flow. San Diego, CA, US.
- 1993. Domain Decomposition for the Front Tracking Reservoir Simulator. Conference. Domain Decomposition for the Front Tracking Reservoir Simulator. State College, PA, US.
- 1993. A Domain Decomposition Approach to Mixed Finte Element Solution of. Conference. A Domain Decomposition Approach to Mixed Finte Element Solution of. Rio de Janeiro, BR.
- 1990. Boron Flushing after BWR ATW. Conference. Boron Flushing after BWR ATW. Nashville, TN, US.
National Presentations
- 2014. Fast Four Dimensional Monte Carlo Dose Computations for Proton Therapy of Lung Cancer. Conference. Fast Four Dimensional Monte Carlo Dose Computations for Proton Therapy of Lung Cancer. Austin, TX, US.
- 2014. Hierarchical Particle Transport in Radiation Therapy. Conference. Hierarchical Particle Transport in Radiation Therapy. Houston, TX, US.
- 2013. Variable RBE and Incidence of Radiation Pneumonitis in Lung Patients Treated with Proton Therapy. Conference. Variable RBE and Incidence of Radiation Pneumonitis in Lung Patients Treated with Proton Therapy. Indianapolis, IN, US.
- 2013. The Impact of Tissue Heterogeneity on Particle Irradiation of the Lung. Conference. The Impact of Tissue Heterogeneity on Particle Irradiation of the Lung. Louisville, KY, US.
- 2010. Biological Effects of Variable RBE in Different Proton Therapy Delivery Modalities. Conference. Biological Effects of Variable RBE in Different Proton Therapy Delivery Modalities. Philadelphia, PA, US.
- 2010. Monte Carlo Computation of RBE-weighted Dose in Prostate Patients Treated with Scanned Proton Beams. Conference. Monte Carlo Computation of RBE-weighted Dose in Prostate Patients Treated with Scanned Proton Beams. Las Vegas, NV, US.
- 2010. Monte Carlo charged particle transport simulation on GPUs. Conference. Monte Carlo charged particle transport simulation on GPUs. Houston, TX, US.
- 2009. The M. D. Anderson experience in developing proton therapy software. Conference. The M. D. Anderson experience in developing proton therapy software. Naperville, IL, US.
- 2008. Comparison of treatment planning dose calculations with Monte Carlo calculations for passively scattered proton radiotherapy beams. Conference. PTCOG 47. Jacksonville, FL, US.
- 2008. Modeling of patient geometry for proton and neutron monte carlo dosimetry. Conference. ICRS-11. Pine Mountain, GA, US.
- 2002. Automatic Code Generation for FFT Algorithms. Conference. Automatic Code Generation for FFT Algorithms. Portland, OR, US.
- 2002. Automatic Code Generation for FFT Algorithms. Conference. IFIP WG 2.5 2002, Workshop on Mathematics of Mathematical Software. Portland, OR, US.
- 2001. Automatic Performance Tuning in UHFFT Library. Conference. ICCS 2001, Conference on Computational Science. San Francisco, CA, US.
- 1996. Numerical Method for a Free Boundary Value Problem Arising in Weak Shock Reflection. Conference. Regional AMS Meeting. Iowa City, IA, US.
- 1996. Finite Element Methods for Partial Differential Equations. Conference. Finite Element Methods for Partial Differential Equations. Ames, IA, US.
International Presentations
- 2024. Radiation Transport Problem in Proton Therapy of Cancer. Invited. Joint meeting of the NZMS/AustMS/AMS. Auckland, NZ.
- 2024. Understanding Radiation-Induced Brain Injury in Proton Therapy of Cancer. Invited. 16 Annual World Cancer Congress. Budapest, HU.
- 2019. Preparing for helium therapy. Conference. PTCOG58. Manchester, GB.
- 2019. Analysis of recurrences in proton therapy of non-small cell lung cancer. Conference. PTCOG58. Manchester, GB.
- 2019. Clinical Impact of Approximations in Analytical Dose Computations in Lung Patients Receiving Proton Therapy. Conference. 12th Annual World Cancer Congress. Osaka, JP.
Formal Peers
- 2012. Monte Carlo Methods in Proton Therapy. Invited. Houston, TX, US.
- 2011. Monte Carlo Methods in Proton Therapy. Invited. Chapel Hill, NC, US.
- 2008. Monte Carlo Computations in Proton Therapy. Invited. Atlanta, GA, US.
- 1997. Nonlinear Filtering for Multi-Models, Renaissance Technologies. Invited. Stony Brook, NY, US.
- 1997. Three dimensional grid generation. Visiting. Stony Brook, NY, US.
- 1996. Finite Element Approximation for the n-Dimensional Fokker-Planck Equation. Invited. Houston, TX, US.
- 1996. Multidimensional Finite Element Package. Invited. Stony Brook, NY, US.
- 1995. Parallel Elliptic Solvers for Reservoir Modeling. Invited. Stony Brook, NY, US.
- 1994. An Efficient Parallel Method for Numerical Simulation of Porous Media Flow. Invited. Ames, IA, US.
- 1993. A Domain Decomposition Approach to Mixed Finite Element Solution of Elliptic Problems. Invited. Ames, IA, US.
Grant & Contract Support
| Date: | 2019 - 2024 |
| Title: | Investigating Patient, Tumor, and Treatment Factors Underlying Sensitivity of Cancers and Normal Tissues to Proton vs Photon Radiation |
| Funding Source: | NIH/NCI |
| Role: | Co-I |
| ID: | FP6212 |
| Date: | 2019 - 2021 |
| Title: | Proton Therapy to Reduce Heart Damage for Lung Cancer Patients |
| Funding Source: | NIH/NCI |
| Role: | Collaborator |
| Date: | 2016 - 2019 |
| Title: | Understanding Biological and Physical Factors Affecting Response to Proton Therapy to Improve its Clinical Effectiveness |
| Funding Source: | Cancer Prevention & Research Institute of Texas (CPRIT) |
| Role: | PI |
| ID: | RP160232 |
| Date: | 2015 - 2018 |
| Title: | Moving proton therapy towards its full potential by using fast Monte Carlo techniquies |
| Funding Source: | Cancer Prevention & Research Institute of Texas (CPRIT) |
| Role: | Principal Investigator-MDACC |
| Date: | 2015 - 2016 |
| Title: | Advancing Linear Energy Transfer Models for Biologically Optimized Proton Therapy |
| Funding Source: | MDACC-IRG |
| Role: | Co-I |
| Date: | 2014 - 2015 |
| Title: | The future of particle therapy: Physics and biology of light ions |
| Funding Source: | UTMDACC - The Center for Radiation Oncology Research |
| Role: | Co-I |
| Date: | 2014 - 2019 |
| Title: | Improving the clinical effectiveness and understanding of the biophysical basis - Project 3: Assessing accuracy of proton therapy and understanding the impact of physical and biophysical factors on its outcomes |
| Funding Source: | NIH/NCI |
| Role: | Co-I |
| ID: | 2U19CA021239-35 |
| Date: | 2014 - 2019 |
| Title: | Improving the Clinical Effectiveness and Understanding of the Biophysical Basis of Proton Therapy: Core B - Clinical & Research Support at MDACC |
| Funding Source: | NIH/NCI |
| Role: | Co-I |
| ID: | 2U19CA021239 |
| Date: | 2014 - 2019 |
| Title: | Improving the Clinical Effectiveness and Understanding of the Biophysical Basis of Proton Therapy: Project 4 - Improving outcomes by optimally exploiting physical and biological characteristics of protons |
| Funding Source: | NIH/NCI |
| Role: | Co-I |
| ID: | 5U19CA021239 |
| Date: | 2014 - 2017 |
| Title: | Mapping Proton RBE Variability Using Automated Biology and Monte Carlo Techniques |
| Funding Source: | NIH/NCI |
| Role: | Co-I |
| ID: | 1R21CA187484-01 |
| Date: | 2013 - 2016 |
| Title: | The future of particle therapy: Physics and biology of light ions |
| Funding Source: | Sister Institution Network Fund Application |
| Role: | Co-I |
| Date: | 2012 - 2016 |
| Title: | Intensity Modulated Particle Therapy |
| Funding Source: | Sister Institution Network Fund |
| Role: | Co-I |
| ID: | SINF MDACC-DKFZ |
| Date: | 2011 - 2015 |
| Title: | In-Situ PET Imaging for Adaptive Proton Therapy |
| Funding Source: | Cancer Prevention & Research Institute of Texas (CPRIT) |
| Role: | Collaborator |
| ID: | RP120326 |
| Date: | 2008 - 2014 |
| Title: | Optimizing Proton Therapy - Core C: Statistics, Data Exchange, Management and Support |
| Funding Source: | NIH/NCI |
| Role: | Co-I |
| ID: | 5P01CA021239-34 |
| Date: | 2008 - 2014 |
| Title: | Optimizing Proton Therapy - Core B: Clinical and Computational Support |
| Funding Source: | NIH/NCI |
| Role: | Co-I |
| ID: | 5P01CA021239-34 |
| Date: | 2004 - 2006 |
| Title: | FFT library Development |
| Funding Source: | Intel Corporation |
| Role: | Co-I |
| Date: | 1999 - 2002 |
| Title: | Grid Application Development Software |
| Funding Source: | National Science Foundation (NSF) |
| Role: | Investigator |
| ID: | R36507-29200099 |
| Date: | 1999 - 2002 |
| Title: | Los Alamos Computer Science Institute |
| Funding Source: | Department of Energy (DOE) |
| Role: | Investigator |
| ID: | R71700K-29200099 |
| Date: | 1997 - 2002 |
| Title: | Scalable Scientific Software Libraries |
| Funding Source: | National Science Foundation (NSF) |
| Role: | Senior Investigator |
| ID: | 1557349-G002632 |
| Date: | 1996 - 1999 |
| Title: | Nonlinear Filtering Approaches to Multitarget Tracking |
| Funding Source: | ONR (Office of Naval Research |
| Role: | Co-I |
| ID: | N00014-96-1-0279 |
| Date: | 1996 - 1997 |
| Title: | ISU Startup Grant |
| Funding Source: | Iowa State University |
| Role: | PI |
Selected Publications
Peer-Reviewed Articles
- Moradi-Kurdestany J, Bartkoski DA, Tailor R, Mirkovic D, Harel Z, Bar-David A, Kleckner M, Borukhin S, Salehpour M. Dosimetry of a novel focused monoenergetic beam for radiotherapy. Phys Med Biol 67(7), 2022. e-Pub 2022. PMID: 35272282.
- Engeseth GM, He R, Mirkovic D, Yepes P, Mohamed ASR, Stieb S, Fuller CD, Wu R, Zhang X, Hysing LB, Pettersen HES, Stokkevåg CH, Mohan R, Frank SJ, Gunn GB. Mixed effect modelling of dose and Linear Energy Transfer correlations with brain image changes after intensity modulated proton therapy for skull base head and neck cancer. Int J Radiat Oncol Biol Phys 111(3):684-692, 2021. e-Pub 2021. PMID: 34153379.
- Bartkoski DA, Bar-David A, Kleckner M, Mirkovic D, Tailor R, Moradi-Kurdestany J, Borukhin S, Harel Z, Burshtein Z, Zuck A, Salehpour M. Analysis of a novel X-ray lens for converging beam radiotherapy. Sci Rep 11(1):19180, 2021. e-Pub 2021. PMID: 34584192.
- Skaarup M, Lundemann MJ, Darkner S, Jørgensen M, Marner L, Mirkovic D, Grosshans D, Peeler C, Mohan R, Vogelius IR, Appelt A. A framework for voxel-based assessment of biological effect after proton radiotherapy in pediatric brain cancer patients using multi-modal imaging. Med Phys 48(7):4110-4121, 2021. e-Pub 2021. PMID: 34021597.
- Lim TY, Mirkovic D, Wang X, Tailor R. Devices for dosimetric measurements and quality assurance of the Xstrahl 300 orthovoltage unit. J Appl Clin Med Phys 22(4):151-157, 2021. e-Pub 2021. PMID: 33733608.
- Christopherson KM, Gunther JR, Fang P, Peterson SL, Roach KE, Wong PF, Mirkovic D, Lim TY, Wang H, Wang XA, Wang C, Garcia J, Dabaja BS, Pinnix CC. Decreased heart dose with deep inspiration breath hold for the treatment of gastric lymphoma with IMRT. Clin Transl Radiat Oncol 24:79-82, 2020. e-Pub 2020. PMID: 32642563.
- Abolfath R, Peeler C, Mirkovic D, Mohan R, Grosshans D. A DNA damage multiscale model for NTCP in proton and hadron therapy. Med Phys 47(4):2005-2012, 2020. e-Pub 2020. PMID: 31955444.
- Kamal M, Peeler CR, Yepes P, Mohamed ASR, Blanchard P, Frank S, Chen L, Jethanandani A, Kuruvilla R, Greiner B, Harp J, Granberry R, Mehta V, Rock C, Hutcheson K, Cardenas C, Gunn GB, Fuller C, Mirkovic D. Radiation-Induced Hypothyroidism After Radical Intensity Modulated Radiation Therapy for Oropharyngeal Carcinoma. Adv Radiat Oncol 5(1):111-119, 2020. e-Pub 2020. PMID: 32051897.
- Yoder AK, Gunther JR, Milgrom SA, Pham M, Hancock D, McSpadden K, Garcia J, Mirkovic D, Dabaja BS, Pinnix CC. Rainbow IMRT and Volumetric Imaging for Anterior Mesenteric Targets. Pract Radiat Oncol 9(3):147-152, 2019. e-Pub 2019. PMID: 30708131.
- Yang P, Xu T, Gomez DR, Deng W, Wei X, Elhalawani H, Jin H, Guan F, Mirkovic D, Xu Y, Mohan R, Liao Z. Patterns of Local-Regional Failure After Intensity Modulated Radiation Therapy or Passive Scattering Proton Therapy With Concurrent Chemotherapy for Non-Small Cell Lung Cancer. Int J Radiat Oncol Biol Phys 103(1):123-131, 2019. e-Pub 2019. PMID: 30165127.
- Yoder AK, Gunther JR, Milgrom SA, Mirkovic D, Nastoupil L, Neelapu S, Fanale M, Fowler N, Westin J, Lee HJ, Rodriguez MA, Iyer SP, Fayad L, Nieto YL, Hosing C, Ahmed S, Medeiros LJ, Khoury JD, Garg N, Amini B, Dabaja BS, Pinnix CC. Hitting a Moving Target: Successful Management of Diffuse Large B-cell Lymphoma Involving the Mesentery With Volumetric Image-guided Intensity Modulated Radiation Therapy. Clin Lymphoma Myeloma Leuk 19(1):e51-e61, 2019. e-Pub 2019. PMID: 30360985.
- Yepes P, Adair A, Frank SJ, Grosshans DR, Liao Z, Liu A, Mirkovic D, Poenisch F, Titt U, Wang Q, Mohan R. Fixed- versus variable-RBE computations for Intensity Modulated Proton Therapy. Adv Radiat Oncol 4(1):156-167, 2019. e-Pub 2019. PMID: 30706024.
- Haas-Kogan D, Indelicato D, Paganetti H, Esiashvili N, Mahajan A, Yock T, Flampouri S, MacDonald S, Fouladi M, Stephen K, Kalapurakal J, Terezakis S, Kooy H, Grosshans D, Makrigiorgos M, Mishra K, Poussaint TY, Cohen K, Fitzgerald T, Gondi V, Liu A, Michalski J, Mirkovic D, Mohan R, Perkins S, Wong K, Vikram B, Buchsbaum J, Kun L. National Cancer Institute Workshop on Proton Therapy for Children: Considerations Regarding Brainstem Injury. Int J Radiat Oncol Biol Phys 101(1):152-168, 2018. e-Pub 2018. PMID: 29619963.
- Taleei R, Guan F, Peeler C, Bronk L, Patel D, Mirkovic D, Grosshans DR, Mohan R, Titt U. Erratum: "Monte Carlo simulations of 3 He ion physical characteristics in a water phantom and evaluation of radiobiological effectiveness" [Med. Phys. 43 (2), page range 761-776(2016)]. Med Phys 45(3):1301, 2018. e-Pub 2018. PMID: 29527699.
- Guan F, Peeler C, Bronk L, Geng C, Taleei R, Randeniya S, Ge S, Mirkovic D, Grosshans D, Mohan R, Titt U. Erratum: "Analysis of the track- and dose-averaged LET and LET spectra in proton therapy using the geant4 Monte Carlo code" [Med. Phys. 42 (11), page range 6234-6247(2015)]. Med Phys 45(3):1302, 2018. e-Pub 2018. PMID: 29527697.
- Yepes P, Adair A, Grosshans D, Mirkovic D, Poenisch F, Titt U, Wang Q, Mohan R. Comparison of Monte Carlo and analytical dose computations for intensity modulated proton therapy. Phys Med Biol 63(4):045003, 2018. e-Pub 2018. PMID: 29339570.
- Taddei PJ, Khater N, Youssef B, Howell RM, Jalbout W, Zhang R, Geara FB, Giebeler A, Mahajan A, Mirkovic D, Newhauser WD. Low- and middle-income countries can reduce risks of subsequent neoplasms by referring pediatric craniospinal cases to centralized proton treatment centers. Biomed Phys Eng Express 4(2), 2018. e-Pub 2018. PMID: 30038799.
- Niedzielski JS, Yang J, Mohan R, Titt U, Mirkovic D, Stingo F, Liao Z, Gomez DR, Martel MK, Briere TM, Court LE. Differences in Normal Tissue Response in the Esophagus Between Proton and Photon Radiation Therapy for Non-Small Cell Lung Cancer Using In Vivo Imaging Biomarkers. Int J Radiat Oncol Biol Phys 99(4):1013-1020, 2017. e-Pub 2017. PMID: 29063837.
- Peeler CR, Mirkovic D, Titt U, Blanchard P, Gunther JR, Mahajan A, Mohan R, Grosshans DR. Clinical evidence of variable proton biological effectiveness in pediatric patients treated for ependymoma. Radiother Oncol 121(3):395-401, 2016. e-Pub 2016. PMID: 27863964.
- Blanchard P, Wong AJ, Gunn GB, Garden AS, Mohamed AS, Rosenthal DI, Morrison WH, Skinner HD, Phan J, Beadle BM, Crutison J, Amin M, Mirkovic D, Zhang X, Zhu XR, Mohan R, Fuller CD, Frank SJ. Toward a Model-Based Strategy for Patient Selection for Proton Therapy-External Validation of Normal Tissue Complication Probability Models on a Head and Neck Proton Cohort. Int J Radiat Oncol Biol Phys 96(2S):S223, 2016. e-Pub 2016. PMID: 27675837.
- Huang JY, Followill DS, Howell RM, Liu X, Mirkovic D, Stingo FC, Kry SF. Approaches to reducing photon dose calculation errors near metal implants. Med Phys 43(9):5117, 2016. e-Pub 2016. PMID: 27587042.
- Yepes PP, Eley JG, Liu A, Mirkovic D, Randeniya S, Titt U, Mohan R. Validation of a track repeating algorithm for intensity modulated proton therapy: clinical cases study. Phys Med Biol 61(7):2633-2645, 2016. e-Pub 2016. PMID: 26961764.
- Taleei R, Guan F, Peeler C, Bronk L, Patel D, Mirkovic D, Grosshans DR, Mohan R, Titt U. Monte Carlo simulations of 3He ion physical characteristics in a water phantom and evaluation of radiobiological effectiveness. Med Phys 43(2):761-776, 2016. e-Pub 2016. PMID: 26843239.
- Guan F, Peeler C, Bronk L, Geng C, Taleei R, Randeniya S, Ge S, Mirkovic D, Grosshans D, Mohan R, Titt U. Analysis of the track- and dose-averaged LET and LET spectra in proton therapy using the geant4 Monte Carlo code. Med Phys 42(11):6234-6247, 2015. e-Pub 2015. PMID: 26520716.
- Titt U, Sell M, Unkelbach J, Bangert M, Mirkovic D, Oelfke U, Mohan R. Degradation of proton depth dose distributions attributable to microstructures in lung-equivalent material. Med Phys 42(11):6425-6432, 2015. e-Pub 2015. PMID: 26520732.
- Rechner LA, Eley JG, Howell RM, Zhang R, Mirkovic D, Newhauser WD. Risk-optimized proton therapy to minimize radiogenic second cancers. Phys Med Biol 60(10):3999-4013, 2015. e-Pub 2015. PMID: 25919133.
- Guan F, Bronk L, Titt U, Lin SH, Mirkovic D, Kerr MD, Zhu XR, Dinh J, Sobieski M, Stephan C, Peeler CR, Taleei R, Mohan R, Grosshans DR. Spatial mapping of the biologic effectiveness of scanned particle beams: towards biologically optimized particle therapy. Sci Rep 5:9850, 2015. e-Pub 2015. PMID: 25984967.
- Zhang R, Mirkovic D, Newhauser WD. Visualization of risk of radiogenic second cancer in the organs and tissues of the human body. Radiat Oncol 10(1):107, 2015. e-Pub 2015. PMID: 25927490.
- Huang JY, Kerns JR, Nute JL, Liu X, Balter PA, Stingo FC, Followill DS, Mirkovic D, Howell RM, Kry SF. An evaluation of three commercially available metal artifact reduction methods for CT imaging. Phys Med Biol 60(3):1047-1067, 2015. e-Pub 2015. PMID: 25585685.
- Shao Y, Sun X, Lou K, Zhu XR, Mirkovic D, Poenisch F, Grosshans D. In-beam PET imaging for on-line adaptive proton therapy: An initial phantom study. Phys Med Biol 59(13):3373-88, 2014. e-Pub 2014. PMID: 24874943.
- Perles LA, Mirkovic D, Anand A, Titt U, Mohan R. LET dependence of the response of EBT2 films in proton dosimetry modeled as a bimolecular chemical reaction. Phys Med Biol 58(23):8477-91, 2013. e-Pub 2013. PMID: 24240474.
- Huang JY, Eklund D, Childress NL, Howell RM, Mirkovic D, Followill DS, Kry SF. Investigation of various energy deposition kernel refinements for the convolution superposition method. Med Phys 40(12):121721, 2013. e-Pub 2013. PMID: 24320507.
- Newhauser WD, Rechner L, Mirkovic D, Yepes P, Koch NC, Titt U, Fontenot JD, Zhang R. Benchmark measurements and simulations of dose perturbations due to metallic spheres in proton beams. Radiat Meas 58:37-44, 2013. e-Pub 2013. PMID: 25147474.
- Zhang R, Fontenot JD, Mirkovic D, Hendricks JS, Newhauser WD. ADVANTAGES OF MCNPX-BASED LATTICE TALLY OVER MESH TALLY IN HIGH-SPEED MONTE CARLO DOSE RECONSTRUCTION FOR PROTON RADIOTHERAPY. Nucl Technol 183(1):101-106, 2013. e-Pub 2013. PMID: 25435594.
- Robertson D, Mirkovic D, Sahoo N, Beddar S. Quenching correction for volumetric scintillation dosimetry of proton beams. Phys Med Biol 58(2):261-273, 2013. e-Pub 2013. PMID: 23257200.
- Wang LL, Perles LA, Archambault L, Sahoo N, Mirkovic D, Beddar S. Determination of the quenching correction factors for plastic scintillation detectors in therapeutic high-energy proton beams. Phys Med Biol 57(23):7767-81, 2012. e-Pub 2012. PMID: 23128412.
- Mirkovic D, Titt U, Mohan R. SU-E-T-484: Potential Clinical Impact of Dosimetric Uncertainties in Proton Therapy. Med Phys 39(6Part17):3816, 2012. e-Pub 2012. PMID: 28517453.
- Titt U, Mirkovic D, Liu A, Mohan R. SU-E-T-435: Automatic Monte Carlo Dose Calculations of Proton Treatment Plans. Med Phys 39(6Part16):3805, 2012. e-Pub 2012. PMID: 28517181.
- Titt U, Mirkovic D, Perles L, Sell M, Peeler C, Liu A, Mohan R. SU-E-T-474: Monte Carlo Phase Space Production to Model Magnetically Scanned Proton Beams for IMPT. Med Phys 39(6Part17):3814, 2012. e-Pub 2012. PMID: 28517438.
- Sell M, Titt U, Perles L, Mirkovic D, Mohan R, Bangert M, Oelfke U. WE-E-BRB-02: Evaluation of Analytical Proton Dose Predictions with a Lung-Like Plastic Phantom. Med Phys 39(6Part27):3956, 2012. e-Pub 2012. PMID: 28520021.
- Perles LA, Mirkovic D, Sawakuchi GO, Titt U. Monte Carlo investigation of rebinning material density distributions of lung parenchyma phantoms in proton therapy. Nuclear Technology 175(1):22-26, 2011. e-Pub 2011.
- Yepes PP, Brannan T, Huang J, Mirkovic D, Newhauser WD, Taddei PJ, Titt U. Application of a Fast Proton Dose Calculation Algorithm to a Thorax Geometry. Radiat Meas 45(10):1367-1368, 2010. e-Pub 2010. PMID: 21544230.
- Taddei PJ, Mahajan A, Mirkovic D, Zhang R, Giebeler A, Kornguth D, Harvey M, Woo S, Newhauser WD. Predicted risks of second malignant neoplasm incidence and mortality due to secondary neutrons in a girl and boy receiving proton craniospinal irradiation. Physics in Medicine and Biology 55(23):7067-7080, 2010. e-Pub 2010. PMID: 21076189.
- Yepes PP, Mirkovic D, Taddei PJ. A GPU implementation of a track-repeating algorithm for proton radiotherapy dose calculations. Physics in Medicine and Biology 55(23):7107-7120, 2010. e-Pub 2010. PMID: 21076192.
- Taddei PJ, Howell RM, Krishnan S, Scarboro SB, Mirkovic D, Newhauser WD. Risk of second malignant neoplasm following proton versus intensity-modulated photon radiotherapies for hepatocellular carcinoma. Physics in Medicine and Biology 55(23):7055-7065, 2010. e-Pub 2010. PMID: 21076199.
- Titt U, Mirkovic D, Sawakuchi GO, Perles LA, Newhauser WD, Taddei PJ, Mohan R. Adjustment of the lateral and longitudinal size of scanned proton beam spots using a pre-absorber to optimize penumbrae and delivery efficiency. Physics in Medicine and Biology 55(23):7097-7106, 2010. e-Pub 2010. PMID: 21076194.
- Sawakuchi GO, Mirkovic D, Perles LA, Sahoo N, Zhu XR, Ciangaru G, Suzuki K, Gillin MT, Mohan R, Titt U. An MCNPX Monte Carlo model of a discrete spot scanning proton beam therapy nozzle. Medical Physics 37(9):4960-4970, 2010. e-Pub 2010. PMID: 20964215.
- Sawakuchi GO, Mirkovic D, Perles LA, Sahoo N, Zhu XR, Ciangaru G, Suzuki K, Gillin MT, Mohan R, Titt U. An MCNPX Monte Carlo model of a discrete spot scanning proton beam therapy nozzle. Med Phys 37(9):4960-70, 2010. e-Pub 2010. PMID: 20964215.
- Sawakuchi GO, Titt U, Mirkovic D, Ciangaru G, Zhu XR, Sahoo N, Gillin MT, Mohan R. Monte Carlo investigation of the low-dose envelope from scanned proton pencil beams. Physics in Medicine and Biology 55(3):711-721, 2010. e-Pub 2010. PMID: 20071752.
- Fontenot JD, Taddei P, Zheng Y, Mirkovic D, Newhauser WD. Ambient Dose Equivalent Versus Effective Dose for Quantifying Stray Radiation Exposures to a Patient Receiving Proton Therapy for Prostate Cancer. Nucl Technol 168(1):173-177, 2009. e-Pub 2009. PMID: 20844596.
- Taddei PJ, Mirkovic D, Fontenot JD, Giebeler A, Zheng Y, Titt U, Woo S, Newhauser WD. Reducing Stray Radiation Dose for a Pediatric Patient Receiving Proton Craniospinal Irradiation. Nuclear Technology 168(1):108-112, 2009. e-Pub 2009. PMID: 20865143.
- Newhauser WD, Fontenot JD, Mahajan A, Kornguth D, Stovall M, Zheng Y, Taddei PJ, Mirkovic D, Mohan R, Cox JD, Woo S. The risk of developing a second cancer after receiving craniospinal proton irradiation. Physics in Medicine and Biology 54(8):2277-2291, 2009. e-Pub 2009. PMID: 19305036.
- Taddei PJ, Mirkovic D, Fontenot JD, Giebeler A, Zheng Y, Kornguth D, Mohan R, Newhauser WD. Stray radiation dose and second cancer risk for a pediatric patient receiving craniospinal irradiation with proton beams. Phys Med Biol 54(8):2259-2275, 2009. e-Pub 2009. PMID: 19305045.
- Newhauser WD, Fontenot JD, Taddei PJ, Mirkovic D, Giebeler A, Zhang R, Mahajan A, Kornguth D, Stovall M, Yepes P, Woo S, Mohan R. Contemporary Proton Therapy Systems Adequately Protect Patients from Exposure to Stray Radiation. AIP Conf Proc 1099(1):450-455, 2009. e-Pub 2009. PMID: 20844607.
- Taddei PJ, Krishnan S, Mirkovic D, Yepes P, Newhauser WD. Effective Dose from Stray Radiation for a Patient Receiving Proton Therapy for Liver Cancer. AIP Conf Proc 1099:445-449, 2009. e-Pub 2009. PMID: 20865142.
- Ezhil M, Vedam S, Balter P, Choi B, Mirkovic D, Starkschall G, Chang JY. Determination of patient-specific internal gross tumor volumes for lung cancer using four-dimensional computed tomography. Radiation Oncology 4:4, 2009. e-Pub 2009. PMID: 19173738.
- Sawakuchi GO, Titt U, Mirkovic D, Mohan R. Density heterogeneities and the influence of multiple Coulomb and nuclear scatterings on the Bragg peak distal edge of proton therapy beams. Physics in Medicine and Biology 53(17):4605-4619, 2008. e-Pub 2008. PMID: 18678928.
- Newhauser WD, Giebeler A, Langen KM, Mirkovic D, Mohan R. Can megavoltage computed tomography reduce proton range uncertainties in treatment plans for patients with large metal implants?. Physics in Medicine and Biology 53(9):2327-2344, 2008. e-Pub 2008. PMID: 18421122.
- Yang XF, Zhang S, bMirkovic D, Zhang QE, Wang H. Different Processing Sites in the Generation of Tumor Antigen Epitopes and Viral Epitopes Suggest New Direction for Anti-Tumor Immunotherapy. Faseb Journal 22, 2008. e-Pub 2008.
- Taddei PJ, Fontenot JD, Zheng Y, Mirkovic D, Lee AK, Titt U, Newhauser WD. Reducing stray radiation dose to patients receiving passively scattered proton radiotherapy for prostate cancer. Physics in Medicine and Biology 53(8):2131-2147, 2008. e-Pub 2008. PMID: 18369278.
- Fontenot J, Taddei P, Zheng Y, Mirkovic D, Jordan T, Newhauser W. Equivalent dose and effective dose from stray radiation during passively scattered proton radiotherapy for prostate cancer. Physics in Medicine and Biology 53(6):1677-1688, 2008. e-Pub 2008. PMID: 18367796.
- Kurzak J, Mirkovic D, Pettitt BM, Johnsson SL. Automatic Generation of FFT for Translations of Multipole Expansions in Spherical Harmonics. International Journal of High Performance Computing Applications 22(2):219-230, 2008. e-Pub 2008. PMID: 19763233.
- Zheng Y, Fontenot J, Taddei P, Mirkovic D, Newhauser W. Monte Carlo simulations of neutron spectral fluence, radiation weighting factor and ambient dose equivalent for a passively scattered proton therapy unit. Physics in Medicine and Biology 53(1):187-201, 2008. e-Pub 2008. PMID: 18182696.
- Canic S, Tambaca J, Mikelic A, Hartley CJ, Mirkovic D, Chavez J, Rosenstrauch D. Blood flow through axially symmetric sections of compliant vessels: new effective closed models. Conf Proc IEEE Eng Med Biol Soc 5:3696-3699, 2007. e-Pub 2007. PMID: 17271096.
- Yang XF, Mirkovic D, Zhang S, Zhang QE, Yan Y, Xiong Z, Yang F, Chen IH, Li L, Wang H. Processing sites are different in the generation of HLA-A2.1-restricted, T cell reactive tumor antigen epitopes and viral epitopes. International Journal Immunopathology Pharmacology 19/4:853-70, 2006. e-Pub 2006. PMID: 17166407.
- Canic S, Ravi-Chandar K, Krajcer Z, Mirkovic D, Lapin S. Mathematical Model analysis of Wallstent and Aneurx: dynamic responses of bare-metal endoprosthesis compared with those of stent-graft. Tex Heart Inst J 32/4(4):502-6, 2005. e-Pub 2005. PMID: 16429893.
- Yang Y, Yang F, Xiong Z, Yan Y, Wang X, Nishino M, Mirkovic D, Nguyen J, Wang H, Yang X. An N-terminal region of translationally controlled tumor protein is required for its antiapoptotic activity. Oncogene 24:4778-4788, 2005. e-Pub 2005. PMID: 15870695.
- Mirkovic D, Johnson SL. Automatic performance tuning for fast fourier transforms. International Journal of High Performance Computing Applications 18/1:47-64, 2004. e-Pub 2004.
- Mirkovic D, Johnson SL. CODELAB: A developers' tool for efficient code generation and optimization. Lecture Notes in Computer Science 2657/4:729-738, 2003. e-Pub 2003.
- Mirkovic D, Johnsson SL. Automatic Performance Tuning in UHFFT Library. Lecture Notes in Computer Science 2073/1:71-80, 2001. e-Pub 2001.
- Canic S, Mirkovic D. A hyperbolic system of conservation laws arising in modeling endovascular treatment of abdominal aortic aneurysm. Hyperbolic Problems: Theory, numerics, applications 141:227-236, 2001. e-Pub 2001.
- Canic S, Mirkovic D. Numericdal study of riemann problems for the two-dimensional unsteady transonic small disturbance equation. SIAM Journal on Applied Mathematics 58:1365-1393, 1998. e-Pub 1998.
- Mirkovic D, Diamond DJ, Hsu CJ, Fitzpatrick R. The potential for catastrophic fuel damage during beyond-design-basis over pressurization accidents in a boiling water reactor. Nuclear Technology 93:158-165, 1991. e-Pub 1991.
- Mirkovic D, Diamond DJ. Effect of flusing of boron during a boiling water reactor anticipated transsient without scram. Nuclear Technology 95:162-174, 1991. e-Pub 1991.
- Diamond DJ, C-J H, Fitzpatrick, R, Mirkovic D. Reactivity accidents with the potential for catastrophic fuel damage. Nuclear Safety 31:311-317, 1990. e-Pub 1990.
- Mirkovic D, Diamond DJ. Boron Flusing during BWR ATWS. Trans of American Nuclear Society 61:222-223, 1990. e-Pub 1990.
Editorials
- Rumbaut RE, Mirkovic D. Magnetic therapy for edema in inflammation: a physiological assessment. Am J Physiol Heart Circ Physiol 294(1):19-20, 2008. PMID: 18032520.
Abstracts
- Wang HC, Rhee DJ, Gao S, Balter P, Phan J, Lee A, Thrower SL, LaNeave S, Ellison D, Schipull E, Hurtt R, Netherton T, Lim TY, Mirkovic D, Luo D, Wang C, Tailor RC, Wong PF, Wang X. Comparison of Flattening Filter Free (FFF) and Flattening Filter (FF) Photon Beam VMAT Plans for Head and Neck Stereotactic Radiotherapy. Medical Physics 50(6):e455, 2023. e-Pub 2023.
- Engeseth GM, He R, Mirkovic D, Yepes P, Stokkevag CH, Wahid KA, Adair A, Wu R, Zhang X, Mohamed AA, Fuller CD, Frank SJ, Mohan R, Gunn GB. NTCP model development and comparison for brain image changes after IMPT for head and neck cancer. Radiotherapy and Oncology 152:S87, 2020. e-Pub 2020.
- Mirkovic D, Bartkoski D, Tailor R, Moradi Kurdestany J, Salehpour M. Beam Modeling for a Novel Convergent X-Ray Treatment Machine. Medical Physics 47(6):58, 2020. e-Pub 2020.
- Mirkovic D, Engeseth G, Yepes P, Mohan R, Frank S, Adair A, Wang Q, Gunn GB. Voxel-Level Analysis of Brain Imaging Changes in Nasopharynx Patients Treated with Proton Therapy. Medical Physics 46(6):585, 2019. e-Pub 2019.
- Peeler C, Titt U, Mohan R, Liao Z, Mirkovic D. Tumor Control Probability for Non-Small Cell Lung Cancer Treated with Proton Therapy: Constant Versus Variable RBE-Weighted Dose. Medical Physics 46(6):587, 2019. e-Pub 2019.
- Titt U, Mirkovic D, Yepes P, Wang Q, Grosshans D, Bangert M, Wieser HP, Mohan R. Detailed Evaluation of Properties of Protons, Helium, and Carbon Ions for Application in a Pediatric Ion Therapy Center. Medical Physics 46(6):587, 2019. e-Pub 2019.
- Adair A, Wang Q, Yepes P, Lin S, Aldehaim M, Titt U, Mirkovic D, Mohan R. Examining the Influence of Variable RBE Models On Passive Scattering Proton Therapy Esophageal Cancer Patients by Means of the Fast Dose Calculator at The University of Texas MD Anderson Cancer Center. Medical Physics 46(6):546, 2019. e-Pub 2019.
- Kamal M, Peeler CR, Yepes P, Mohamed AS, Frank SJ, Chen L, Jethanandani A, Kuruvilla R, Greiner B, Harp J, Granberry R, Mehta VK, Rock C, Cardenas CE, Hutcheson KA, Gunn GB, Fuller CD, Mirkovic D. Radiation-Induced Hypothyroidism after Radical Intensity-Modulated Radiation Therapy for Oropharyngeal Carcinoma. International Journal of Radiation Oncology Biology Physics 102(3):S7 - S8, 2018. e-Pub 2018.
- Mirkovic D, Yepes P, Titt U, Peeler CR, Liao Z, Mohan R. Clinical Impact of Approximations in Analytical Dose Computations in Lung Patients Receiving Proton Therapy. Medical Physics 45(6), 2018. e-Pub 2018.
- Martin R, Williamson T, Yepes P, Poenisch F, Melkun M, Titt U, Mirkovic D, Beddar S, Mohan R, Holliday E, Sawakuchi G. Intensity Modulated Proton Therapy (IMPT) for Anal Canal Cancer. Medical Physics 45(6), 2018. e-Pub 2018.
- Yepes P, Adair A, Titt U, Mirkovic D, Wang Q, Poenisch F, Frank S, Liao Z, Mohan R. Fixed- Versus Variable-RBE Computations for Intensity-Modulated Proton Therapy. Medical Physics 45(6), 2018. e-Pub 2018.
- Branco D, Taylor P, Kry S, Mirkovic D, Followill D. Evaluation of Proton Therapy Dose Calculations in a Simple Geometrical Static Lung Phantom. Medical Physics 45(6), 2018. e-Pub 2018.
- Adair A, Wang Q, Yepes P, Titt U, Mirkovic D, Mohan R. Patient Based Validation and Improvement of the Laboratory Based Calibration of the Fast Dose Calculator for Passive Scattering Proton Therapy at The University of Texas MD Anderson Cancer Center. Medical Physics 45(6), 2018. e-Pub 2018.
- Martin R, Williamson T, Yepes P, Colbert L, Poenisch F, Mirkovic D, Titt U, Mohan R, Beddar S, Taniguchi C, Sawakuchi G. Hypofractionated Intensity Modulated Proton Therapy (IMPT) for Locally Advanced Pancreatic Cancer. Medical Physics 45(6), 2018. e-Pub 2018.
- Peeler CR, Grosshans DR, Mohan R, Tran K, McGovern S, Bishop A, Mirkovic D. Analysis of Radiation-Induced Visual Toxicity in Meningioma Treatment: Protons Vs. Photons. Medical Physics 45(6), 2018. e-Pub 2018.
- Adair A, Yepes P, Titt U, Mirkovic D, Mohan R. Commissioning of the Fast Dose Calculator for Passive Scattering Proton Therapy at The University of Texas MDAnderson Cancer Center. Medical Physics 44(6):3149, 2017. e-Pub 2017.
- Yepes P, Adair A, Liu A, Mirkovic D, Titt U, Wang Q, Mohan R. Retrospective Dosimetric Analysis of Large Cohorts of Patients, the Tool and First Results. Medical Physics 44(6):3122, 2017. e-Pub 2017.
- Branco D, Taylor P, Mirkovic D, Zhang X, Yepes P, Kry S, Sahoo N, Followill D. Evaluation of Proton Therapy Analytic Algorithm Distal Dose Calculation in Static Lung Phantom. Medical Physics 44(6):3045, 2017. e-Pub 2017.
- Titt U, Yang J, Mirkovic D, Yepes P, Liu A, Peeler CR, Mohan R. Monte Carlo Cumulative 4D and 5D Proton Dose Distribution Computations and Their Comparison with Analytical Dose Computation Model Predictions for Lung Cancer Patients. Medical Physics 44(6):3041, 2017. e-Pub 2017.
- Mirkovic D, Yang P, Belal Z, Titt U, Peeler CR, Liao Z, Mohan R. Analysis of Recurrences in Lung Patients Treated with Protons. Medical Physics 44(6):2848, 2017. e-Pub 2017.
- Court L, Niedzielski J, Titt U, Yang J, Mohan R, Mirkovic D, Stingo F, Gomez D, Liao Z, Martel M, Briere T, Court L. Analysis of Normal Tissue Response in the Esophagus Between IMRT and Proton Therapy Using Imaging Biomarkers. Medical Physics 44(6):2748, 2017. e-Pub 2017.
- Peeler CR, Titt U, Grosshans DR, Liao Z, Mohan R, Mirkovic D. Analysis of Differences in Tumor Control Probability Calculated From Monte Carlo and Treatment Planning System Dose Distributions for Proton Therapy. Medical Physics 44(6):2748, 2017. e-Pub 2017.
- Guan F, Bronk L, Kerr M, Wang X, Li Y, Peeler C, Sahoo N, Patel D, Mirkovic D, Titt U, Grosshans D, Mohan R. Investigation of LET Spectral Dependence of the Biological Effects of Therapeutic Protons, AAPM 2016 Washington, DC. Medical Physics 43(6):3843, 2016. e-Pub 2016. PMID: 28047702.
- Peeler C, Mirkovic D, Titt U, Grosshans D, Mohan R. Voxel-Level Analysis of Adverse Treatment Response in Pediatric Patients Treated for Ependymoma with Passive Scattering Proton Therapy, AAPM 2016 Washington, DC. Medical Physics 43(6):3828-3829, 2016. e-Pub 2016. PMID: 28048899.
- Yepes P, Titt U, Mirkovic D, Liu A, Frank S, Mohan R. Are the Approximations in Analytic Semi-Empirical Dose Calculation Algorithms for Intensity Modulated Proton Therapy for Complex Heterogeneities of Head and Neck Clinically Significant?, AAPM 2016 Washington, DC. Medical Physics 43(6):3496, 2016. e-Pub 2016. PMID: 28048730.
- Kim D, Titt U, Mirkovic D. Uptake Dose Response in Lung Correlates Linearly with Proton Therapy Dose, AAPM 2016 Washington, DC. Medical Physics 43(6):3491-3492, 2016. e-Pub 2016. PMID: 28048762.
- Titt U, Mirkovic D, Yepes P, Liu A, Peeler C, Randenyia S, Mohan R. 4D and 5D Proton Dose Evaluation with Monte Carlo, AAPM 2016 Washington, DC. Medical Physics 43(6):3489-3490, 2016. e-Pub 2016. PMID: 28046764.
- Mirkovic D, Titt U, Yepes P, Mohan R. Effects of Motion and Variable RBE in a Lung Patient Treated with Passively Scattered Protons, AAPM 2016 Washington, DC. Medical Physics 43(6):3336, 2016. e-Pub 2016. PMID: 28047696.
- Patel D, Bronk L, Guan F, Peeler C, Mirkovic D, Grosshans D, Jakel O, Abdollahi A, Titt U, Mohan R. Experimental Investigation of RBE for Lung Cancer Cell Lines as a Function of Dose and LET in Proton, Helium and Carbon Beams, AAPM 2016 Washington, DC. Medical Physics 43(6):3843-3844, 2016. e-Pub 2016. PMID: 28047053.
- Kerr M, Bronk L, Guan F, Patel D, Li Y, Wang X, Sahoo N, Peeler C, Titt U, Mirkovic D, Grosshans D, Mohan R. Spatial Mapping of Scanned Proton Biologic Effect Using the High-Throughput Technique, Continued, AAPM 2016 Washington, DC. Medical Physics 43(6):3888, 2016. e-Pub 2016. PMID: 28046268.
- Taleei R, Peeler C, Guan F, Patel D, Titt U, Mirkovic D, Grosshans D, Mohan R. Modeling Biological Response to Proton Irradiation and Evaluating Its Potential Clinical Consequences, AAPM 2015 Anaheim, California. Medical Physics 42(6):3461, 2015. e-Pub 2015. PMID: 26128210.
- Huang J, Followill D, Howell R, Liu X, Mirkovic D, Stingo F, Kry S. Dosimetric Impact of Implementing Metal Artifact Reduction Methods and Metal Energy Deposition Kernels for Photon Dose Calculations, AAPM 2015 Anaheim, California. Medical Physics 42(6):3409, 2015. e-Pub 2015. PMID: 26127995.
- Guan F, Titt U, Patel D, Bronk L, Taleei R, Peeler C, Mirkovic D, Grosshans D, Jakel O, Mohan R. Experimental Design for High-Throughput In-Vitro RBE Measurements Using Protons, Helium and Carbon Ions, AAPM 2015 Anaheim, California. Medical Physics 42(6):3675, 2015. e-Pub 2015. PMID: 26129285.
- Guan F, Bronk L, Kerr M, Titt U, Wang X, Taleei R, Peeler C, Patel D, Mirkovic D, Grosshans D, Mohan R. Quantifying the Biological Effects of Therapeutic Protons by LET Spectrum Analysis, AAPM 2015 Anaheim, California. Medical Physics 42(6):3616, 2015. e-Pub 2015. PMID: 26128964.
- Peeler C, Taleei R, Guan F, Bronk L, Patel D, Titt U, Mirkovic D, Stewart R, Grosshans D, Mohan R. Relative Biological Effectiveness of Double-Strand Break Induction for Modeling Cell Survival in Pristine Proton Beams of Different Dose-Averaged Linear Energy Transfers, AAPM 2015 Anaheim, California. Medical Physics 42(6):3529, 2015. e-Pub 2015. PMID: 26128495.
- Yepes P, Mirkovic D, Mohan R. Track Repeating Algorithm for Proton Therapy Applied to Intensity Modulated Proton Therapy for Head-And-Neck Patients, AAPM 2015 Anaheim, California. Medical Physics 42:3513, 2015. e-Pub 2015. PMID: 26128429.
- Mirkovic D, Peeler C, Grosshans D, Titt U, Taleei R, Mohan R. Modeling Relative Biological Effectiveness of Protons for Radiation Induced Brain Necrosis, AAPM 2015 Anaheim, California. Medical Physics 42(6):3461, 2015. e-Pub 2015. PMID: 26128212.
- Guan F, Bronk L, Kerr M, Titt U, Taleei R, Mirkovic D, Zhu X, Grosshans D, Mohan R. The Effect of Particle Tracking Step Size Limit On Monte Carlo-Computed LET Spectrum of Therapeutic Proton Beams, AAPM 2014 Austin, Texas. Medical Physics 41(6):534, 2014. e-Pub 2014.
- Huang J, Kerns J, Nute J, Liu X, Stingo F, Followill D, Mirkovic D, Howell R, Kry S. Evaluation of Three Commercial Metal Artifact Reduction Methods for CT Simulations in Radiation Therapy Treatment Planning, AAPM 2014 Austin, Texas. Medical Physics 41:498, 2014. e-Pub 2014.
- Mirkovic D, Yepes P, Titt U, Mohan R. Fast Four Dimensional Monte Carlo Dose Computations for Proton Therapy of Lung Cancer, AAPM 2014 Austin, Texas. Medical Physics 41:535, 2014. e-Pub 2014.
- Taleei R, Titt U, Peeler C, Guan F, Mirkovic D, Grosshans D, Mohan R. Modeling Physics Properties and Biologic Effects Induced by Proton and Helium Ions, AAPM 2014 Austin, Texas. Medical Physics 41(6):534, 2014. e-Pub 2014.
- Bronk L, Guan F, Kerr M, Dinh J, Titt U, Mirkovic D, Lin S, Mohan R, Grosshans D. High-Throughput Mapping of Proton Biologic Effect, AAPM 2014 Austin, Texas. Medical Physics 41(6):505, 2014. e-Pub 2014.
- Randeniya S, Mirkovic D, Titt U, Guan F, Mohan R. Importance of Energy Dependent Protons Per MU Calibration Factors in IMPT Dose Calculations Using Monte Carlo Technique, AAPM 2014 Austin, Texas. Medical Physics 41(6), 2014. e-Pub 2014.
- Titt U, Mirkovic D, Liu A, Anand A, Perles L, Ciangaru G, Mohan R. Commissioning of the MC2 Monte Carlo Dose Computation Engine, AAPM 2014 Austin, Texas. Medical Physics 41:362, 2014. e-Pub 2014.
- Peeler C, Taleei R, Guan F, Bronk L, Grosshans D, Mirkovic D, Titt U, Mohan R. Application of the Repair-Misrepair-Fixation RBE Model to Describe the Results of High Resolution Proton Irradiation Cell Survival Experiments, AAPM 2014 Austin, Texas. Medical Physics 41(6):232, 2014. e-Pub 2014.
- Lou K, Mirkovic D, Sun X, Zhu X, Poenisch F, Grosshans D, Clark J, Shao Y. Intra-Fraction Proton Beam-Range Verification with PET Imaging: Feasibility Studies with Monte Carlo Simulations and Statistical Modeling, AAPM 2014 Austin, Texas. Medical Physics 41:174, 2014. e-Pub 2014.
- Titt U, Guan F, Mirkovic D, Mohan R. On the Out-Of-Field-Doses Caused by Secondary Particles From Light Ion Beams in Charged Particle Therapy, AAPM 2013 Indianapolis, Indiana. Medical Physics 40(6):328, 2013. e-Pub 2013.
- Perles LA, Titt U, Mirkovic D, Mohan R. Modeling the Cell Inactivation Process for High LET Particles by Using the Law of Mass Action, AAPM 2013 Indianapolis, Indiana. Medical Physics 40(6):272, 2013. e-Pub 2013.
- Huang J, Eklund D, Childress N, Howell R, Mirkovic D, Kry S. Dosimetric Impact of Implementing Kernel Hardening and Material-Specific Kernels in the Convolution/Superposition Method, AAPM 2013 Indianapolis, Indiana. Medical Physics 40(6):333, 2013. e-Pub 2013.
- Shao Y, Sun X, Lou K, Zhu X, Mirkovic D, Poenisch F, Grosshans D. In-Beam PET Imaging with Depth-Of-Interaction Measurement for Accurate Proton Beam-Range Verification, AAPM 2013 Indianapolis, Indiana. Medical Physics 40(6):503, 2013. e-Pub 2013.
- Peeler C, Mirkovic D, Perles L, Titt U, Grosshans D, Mohan R. Comparison of Results for RBE-Weighted Dose From Two RBE Models for Proton Therapy Treatment Plans, AAPM 2013 Indianapolis, Indiana. Medical Physics 40(6):552, 2013. e-Pub 2013.
- Mirkovic D, Titt U, Peeler C, Perles L, Liao Z, Mohan R. Variable RBE and Incidence of Radiation Pneumonitis in Lung Patients Treated with Proton Therapy, AAPM 2013 Indianapolis, Indiana. Medical Physics 40(6):455, 2013. e-Pub 2013.
- Guan F, Mohan R, Dinh J, Kerr M, Perles L, Mirkovic D, Titt U, Zhu X, Gillin M, Meyn R, Lin S, Grosshans D. Experimental Design and Preliminary Results for High-Resolution and High-Throughput In-Vitro Measurements of Proton RBE, AAPM 2013 Indianapolis, Indiana. Medical Physics 40(6):552, 2013. e-Pub 2013.
- Taddei PJ, Khater N, Youssef B, Jalbout W, Howell RM, Mahajan A, Zhang R, Mirkovic D, Giebeler A, Geara FB, Newhauser WD. Equivalent Dose in Children Receiving Craniospinal Irradiation with Photons in a Developing Country Or with Protons in a Developed Country, AAPM 2013 Indianapolis, Indiana. Medical Physics 40(6):267, 2013. e-Pub 2013.
- Titt U, Mirkovic D, Mohan R. Three-Dimensional Energy Fluence Estimates for Future Treatment Planning Systems, AAPM 2013 Indianapolis, Indiana. Medical Physics 40:88, 2013. e-Pub 2013.
- Titt U, Liu A, Mirkovic D. Runtime Optimization for the Automatic Monte Carlo Dose Computation System MC2, AAPM 2013 Indianapolis, Indiana. Medical Physics 40:326, 2013. e-Pub 2013.
- Lou K, Mirkovic D, Sun XS, Zhu XR, Clark J, Shao YP. Monte Carlo Simulation Study of In-beam Intra-treatment PET Imaging for Adaptive Proton Therapy - 2013 60th IEEE Nuclear Science Symposium (NSS) / Medical Imaging Conference (MIC) / 20th International Workshop on Room-Temperature Semiconductor X-ray and Gamma-ray Detectors, Seoul, South Korea, 2013. e-Pub 2013.
- Mirkovic D, Peeler C, Grosshans D, Titt U, Mohan R. Is Constant RBE Accurate Enough for Determination of Biological Effects in Proton Therapy?. International Journal of Radiation Oncology Biology Physics 84(3), 2012. e-Pub 2012.
- Peeler C, Mirkovic D, Grosshans D, Titt U, Mohan R. Correlating Areas of Radiation Toxicity with Relative Biological Effectiveness-Weighted Dose Distributions in Proton Radiotherapy, AAPM 2012 Charlotte, North Carolina. Medical Physics 39(6):3994, 2012. e-Pub 2012.
- Sell M, Titt U, Perles L, Mirkovic D, Mohan R, Bangert M, Oelfke U. Evaluation of Analytical Proton Dose Predictions with a Lung-Like Plastic Phantom, AAPM 2012 Charlotte, North Carolina. Medical Physics 39(6):3956, 2012. e-Pub 2012.
- Perles L, Mirkovic D, Anand A, Titt U, Mohan R. Dose Response of EBT2 Film Modeled as a Bimolecular Reaction, AAPM 2012 Charlotte, North Carolina. Medical Physics 39(6):4009, 2012. e-Pub 2012.
- Mirkovic D, Titt U, Mohan R. Potential Clinical Impact of Dosimetric Uncertainties in Proton Therapy, AAPM 2012 Charlotte, North Carolina. Medical Physics 39:3816, 2012. e-Pub 2012.
- Titt U, Mirkovic D, Liu A, Mohan R. Automatic Monte Carlo Dose Calculations of Proton Treatment Plans, AAPM 2012 Charlotte, North Carolina. Medical Physics 39(6):3805, 2012. e-Pub 2012.
- Titt U, Mirkovic D, Perles L, Sell M, Peeler C, Liu A, Mohan R. Monte Carlo Phase Space Production to Model Magnetically Scanned Proton Beams for IMPT, AAPM 2012 Charlotte, North Carolina. Medical Physics 39(6):3814, 2012. e-Pub 2012.
- Robertson D, Mirkovic D, Beddar S. A Quenching Correction Method for Volumetric Scintillation Dosimetry of Proton Beams, AAPM 2012 Charlotte, North Carolina. Medical Physics 39:3886, 2012. e-Pub 2012.
- Mirkovic D, Titt U, Mohan R. Accuracy of Patient Dose Calculation in Proton Therapy of Lung Cancer: A Comparison of Monte Carlo and Pencil Beam Computations, AAPM 2011 Vancouver, Canada. Medical Physics 38:3642, 2011. e-Pub 2011.
- Wang L, Perles L, Archambault L, Sahoo N, Beddar S, Mirkovic D. Application of a Plastic Scintillation Detector in Measuring Depth-Dose Curves for Passive-Scattering Proton Beams, AAPM 2011 Vancouver, Canada. Medical Physics 38(6):3366, 2011. e-Pub 2011.
- Faught A, Mirkovic D. Implementation of a One Dimensional Analytical Model for Calculating Three Dimensional Linear Energy Transfer in Proton Radiotherapy, AAPM 2011 Vancouver, Canada. Medical Physics 38(6):3659, 2011. e-Pub 2011.
- Titt U, Mirkovic D, Anand A, Perles LA, Sawakuchi GO, Mohan R. On the Dependence of Scanned Proton Beam Dose Output Factors On the Field Size and the Accuracy of the Lateral Dose Profiles, AAPM 2011 Vancouver, Canada. Medical physics 38(6):3382, 2011. e-Pub 2011.
- Perles LA, Ibbott G, Blatnica A, Mirkovic D, Titt U, Gillin M, Mohan R. 3D Proton Dose Distributions in An Anthropomorphic Lung Phantom, Comparing Monte Carlo, Film, and TLD Measurements, AAPM 2011 Vancouver, Canada. Medical Physics 38(6):3780, 2011. e-Pub 2011.
- Yepes P, Mirkovic D, Keyes R, Panchal P. Online Monte-Carlo-Accurate Real-Time Proton Dose Calculator, AAPM 2011 Vancouver, Canada. Medical Physics 38(6):3650, 2011. e-Pub 2011.
- Randeniya SD, D Mirkovic D, Kry S, Titt U, Newhauser WD, Howell RM. Patient Specific Out-Of-Field Dose Calculation Tool for 6MV and 18MV: Development and Validation, AAPM 2011 Vancouver, Canada. Medical Physics 38(6):3736, 2011. e-Pub 2011.
- Robertson D, Mirkovic D, Mohan R, Beddar S. Voxelized Quenching Correction for Proton Pencil Beams in a Liquid Scintillator Detector, AAPM 2011 Vancouver, Canada. Medical Physics 38(6):3816, 2011. e-Pub 2011.
- Taddei PJ, Jalbout WT, Geara FB, Mirkovic D, Howell RM, Zhang R, Giebeler A, Mahajan A, Newhauser WD. Comparison of the Risk of Second Malignant Neoplasm in a Developed Country Versus a Developing Country for a 13-Year-Old Girl Receiving Craniospinal Irradiation, AAPM 2011 Vancouver, Canada. Medical Physics 38(6):3736, 2011. e-Pub 2011.
- Mohan R, Mirkovic D, Titt U, Song X, Zhu XR, Gillin MT. Experimental Assessment of the Accuracy of a Semi-Empirical Model and a Monte Carlo System for Proton Dose Calculations for Highly Inhomogeneous Media, AAPM 2011 Vancouver, Canada. Medical Physics 38(6):3648, 2011. e-Pub 2011.
- Randeniya S, Mirkovic D, Kry S, Titt U, Newhauser W, Howell R. Automated Photon Monte Carlo Linear Accelerator Model for Calculating In‐Field and Out‐Of‐Field Dose, AAPM 2010 Philadelphia, Pennsylvania. Medical Physics 37(6):3281, 2010. e-Pub 2010.
- Perles L, Sawakuchi G, Mirkovic D, Mohan R, Titt U. Monte Carlo Investigation and Measurements of Distal Edge Degradation in Lung Phantoms with Therapeutic Proton Beams, AAPM 2010 Philadelphia, Pennsylvania. Medical Physics 37(6):3145, 2010. e-Pub 2010.
- Rechner L, Mirkovic D, Fontenot J, Newhauser W. Modeling Multiple Coulomb Scattering in Therapeutic Proton Beams: A Comparison of Two Algorithms, AAPM 2010 Philadelphia, Pennsylvania. Medical Physics 37(6):3282, 2010. e-Pub 2010.
- Bednarz B, Mirkovic D, Titt U, Paganetti H. A Joint Research Investigation Comparing MCNPX and Geant4 Monte Carlo Codes to Reduce the Range Uncertainties in Proton Therapy, AAPM 2010 Philadelphia, Pennsylvania. Medical Physics 37(6):3286, 2010. e-Pub 2010.
- Titt U, Mirkovic D, Sawakuchi G, Perles L, Newhauser W, Taddei P, Mohan R. Adjustment of Lateral and Longitudinal Size of Scanned Proton‐Beam Spots Using a Pre‐Absorber, AAPM 2010 Philadelphia, Pennsylvania. Medical Physics 37(6):3353, 2010. e-Pub 2010.
- Mirkovic D, Titt U, Sawakuchi G, Mohan R. Biological Effects of Variable RBE in Different Proton Therapy Delivery Modalities, AAPM 2010 Philadelphia, Pennsylvania. Medical Physics 37:3365, 2010. e-Pub 2010.
- Perles LA, Mirkovic D, Sawakuchi GO, Titt U. 16th Biennial Topical Meeting of the American-Nuclear-Society (ANS) and Radiation Protection and Shielding Division (RPSD) 2010, Las Vegas, Nevada. Nuclear Technology 175(1(S1)), 2010. e-Pub 2010.
- Yepes PP, Brannan T, Huang J, Mirkovic D, Newhauser WD, Taddei PJ, Phillip J, Titt U. Application of a fast proton dose calculation algorithm to a thorax geometry - 11th Neutron and Ion Dosimetry Symposium 2009 Cape Town, South Africa. Radiation Measurements 45(10(S1)):1367-1368, 2009. e-Pub 2009.
- Taddei PJ, Mirkovic D, Fontenot JD, Giebeler A, Zheng Y, Titt U, Woo S, Newhauser WD. Reducing Stray Radiation Dose for a Pediatric Patient Receiving Proton Craniospinal Irradiation - 11th International Conference on Radiation Shielding / 15th Topical Meeting of the Radiation Protection and Shielding Division 2008 Pine Mount, Georgia. Nuclear Technology 168(1):108-112, 2009. e-Pub 2009.
- Fontenot JD, Taddei P, Zheng YS, Mirkovic D, Newhauser WD. Ambient Dose Equivalent versus Effective Dose for Quantifying Stray Radiation Exposures to a Patient Receiving Proton Therapy for Prostate Cancer - 11th International Conference on Radiation Shielding / 15th Topical Meeting of the Radiation Protection and Shielding Division 2008 PIne Mount, Georgia. Nuclear Technology 168(1):173-177, 2009. e-Pub 2009.
- Sawakuchi G, Titt U, Mirkovic D, Zhu X, Sahoo N, Bues M, Ciangaru G, Poenisch F, Suzuki K, Arjomandy B, Gillin M, Mohan R. Validation of An MCNPX Monte Carlo Model of a Discrete-Spot Scanning Beam Nozzle and Evaluation of the Beamlet Lateral Envelope of Low Doses, AAPM 2009 Anaheim, California. Medical Physics 36(6):2782-2783, 2009. e-Pub 2009.
- Harvey MC, Taddei PJ, Mirkovic D, Newhauser WD. Nuclear Model Evaluation of Uncertainties in Therapeutic Absorbed Dose and Secondary Neutron Production in Proton Radiotherapy using MCNPX, AAPM 2009 Anaheim, California. Medical Physics 36(6):2702, 2009. e-Pub 2009.
- Mirkovic D, Titt U, Sawakuchi GO, Zhang X, Li Y, Mohan R. Monte Carlo computation of the effective dose in scanning beam proton therapy, AAPM 2009 Anaheim, California. Medical Physics 36(6):2612, 2009. e-Pub 2009.
- Taddei PJ, Mirkovic D, Fontenot JD, Zheng Y, Kornguth D, Mohan R, Newhauser WD. Second Cancer Risk from Secondary Neutrons for a Boy who Received Proton Craniospinal Irradiation, AAPM 2009 Anaheim, California. Medical Physics 36(6):2628, 2009. e-Pub 2009.
- Sawakuch G, Titt U, Ciangaru G, Mirkovic D, Zhu X, Mohan R. The Causes of the Lateral Envelop of Low Doses in Scanning Proton Beamlets, AAPM 2009 Anaheim, California. Medical Physics 36(6):2620, 2009. e-Pub 2009.
- Yepes P, Randeniya S, Taddei PJ, Mirkovic D, Newhauser WD. Reducing the Simulation Time of a Prostate Cancer Clinical Setup by Two Orders of Magnitude, AAPM 2009 Anaheim, California. Medical Physics 36(6):2622, 2009. e-Pub 2009.
- Peng Y, Balter P, Mirkovic D, Vedam S. Real-time characterization of respiratory motion regularity during radiation therapy, AAPM 2009 Anaheim, California. Medical Physics 36(6):2503, 2009. e-Pub 2009.
- Taddei PJ, Krishnan S, Mirkovic D, Yepes P, Newhauser WD. Effective Dose from Stray Radiation for a Patient Receiving Proton Therapy for Liver Cancer - 20th International Conference on Application of Accelerators in Research and Industry 2008, Ft. Worth, Texas. Application of Accelerators in Research and Industry 1099:445-449, 2009. e-Pub 2009.
- Newhauser WD, Fontenot JD, Taddei PJ, Mirkovic D, Giebeler A, Zhang R, Mahajan A, Kornguth D, Stovall M, Yepes P, Woo S, Mohan R. Contemporary Proton Therapy Systems Adequately Protect Patients from Exposure to Stray Radiation - 20th International Conference on Application of Accelerators in Research and Industry 2008, Fort Worth, Texas. Application of Accelerators in REsearch and Industry 1099:450-455, 2009. e-Pub 2009.
- Titt U, Zhang X, Li Y, Mirkovic D, Sawakuchi G, Mohan R. Monte Carlo Study of Distal Edge Degradation in Proton Therapy Due to Heterogeneities. Proof of Principle with a Case Study, AAPM 2008 Houston, Texas. Medical Physics 35:2798, 2008. e-Pub 2008.
- Mirkovic D, Vedam S, Chang JY. Volumetric Analysis of Moving Structures in Radiation Treatment Planning, AAPM 2008 Houston, Texas. Medical Physics 35:2834, 2008. e-Pub 2008.
- Taddei PJ, Mirkovic D, Fontenot JD, Giebeler A, Zheng Y, Titt U, Woo S, Newhauser WD. Reducing Stray Radiation Dose for a Pediatric Patient Receiving Craniospinal Irradiation with Protons, AAPM 2008 Houston, Texas. Medical Physics 35(6), 2008. e-Pub 2008.
- Taddei P, Fontenot J, Zheng Y, Mirkovic D, Titt U, Newhauser W. Monte Carlo Investigation of Local Shielding to Reduce Stray Radiation Doses to Patients Receiving Proton Therapy, AAPM 2007 Minneapolis, Minnesota. Medical Physics 34(6):2471, 2007. e-Pub 2007.
- Newhauser W, Fontenot J, Zheng Y, Taddei P, Mirkovic D, Titt U, Zhu X, Sahoo N, Schaffner B, Langenegger A, Koch N, Zhang X, Mohan R. A Monte-Carlo Based Dose Engine for Proton Radiotherapy Treatment Planning. Medical Physics 34(6):2406, 2007. e-Pub 2007.
- Kang Y, Mirkovic D, Dong L. Sensitivity of Proton and Photon Plans to the Intra- and Inter-Fractional Changes in Patient's Anatomy, AAPM 2007 Minneapolis, Minnesota. Medical Physics 34:2390, 2007. e-Pub 2007.
- Newhauser W, Fontenot J, Zheng Y, Taddei P, Mirkovic D, Titt U, Zhu X, Sahoo N, Schaffner B, Langenegger A, Koch N, Zhang X, Mohan R. A Monte-Carlo Based Dose Engine for Proton Radiotherapy Treatment Planning, AAPM 2007 Minneapolis, Minnesota. Medical Physics 34:2406, 2007. e-Pub 2007.
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CV information above last modified March 26, 2026