Eduardo Yepez Guevara, MD, FACP
Department of Infectious Diseases, Infection Control, and Employee Health, Division of Internal Medicine
Present Title & Affiliation
Primary Appointment
Assistant Professor, Department of Infectious Diseases, Infection Control and Employee Health, Division of Internal Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX
Fellowship Program Associate Director, Department of Infectious Diseases, Infection Control and Employee Health, Division of Internal Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX
Education & Training
Degree-Granting Education
| 2006 | Universidad Nacional de Trujillo, Trujillo, PER, MD, Medicine |
Postgraduate Training
| 2018-2019 | Clinical Fellowship, Transplantation Infectious Diseases, The University of Texas Health Science Center at Houston, Houston, TX |
| 2016-2018 | Clinical Fellowship, Infectious Diseases, The University of Texas Health Science Center at Houston, Houston, TX |
| 2011-2013 | Clinical Residency, Internal Medicine, New York Medical College - Metropolitan Hospital, New York, NY |
| 2010-2011 | Clinical Internship, Internal Medicine, New York Medical College - Metropolitan Hospital, New York, NY |
| 2008-2010 | House Physician in Clinical Immunology, University of Miami - Jackson Memorial Hospital, Miami, FL |
Board Certifications
| 2018 | American Board of Internal Medicine - Infectious Disease |
| 2013 | American Board of Internal Medicine - Internal Medicine |
Experience & Service
Academic Appointments
Assistant Professor, Department of General Internal Medicine, Division of Internal Medicine, New York Medical College - Metropolitan Hospital, New York, NY, 2013 - 2016
Administrative Appointments/Responsibilities
Rotation Site Associate Director, Baylor and UTHSC Rotating Fellows, Houston, TX, 2022 - Present
Core Faculty- Infectious Disease Fellowship, Department of Infectious Diseases, Baylor College of Medicine Infectious Disease Fellowship, Houston, TX, 2022 - Present
Core Faculty- Infectious Disease Fellowship, Department of Infectious Diseases, University of Texas Health Science Center at Houston - MD Anderson Cancer Center, Houston, TX, 2022 - Present
Chief Clinical Fellow in Infectious Diseases, Department of Infectious Diseases, The University of Texas Health Science Center at Houston, Houston, TX, 2017 - 2018
Member, Clinical Competence Committee, Department of General Internal Medicine, New York Medical College - Metropolitan Hospital, New York, NY, 2013 - 2016
Chief Medical Resident, Department of General Internal Medicine, New York Medical College - Metropolitan Hospital, New York, NY, 2013 - 2013
Assistant Chief Medical Resident, Department of General Internal Medicine, New York Medical College - Metropolitan Hospital, New York, NY, 2012 - 2013
Other Appointments/Responsibilities
Attending Physician, New York Medical College - Metropolitan Hospital, New York, NY, 2013 - 2016
Institutional Committee Activities
Co-lead for the Educate the Educator working group, Division of Internal Medicine Education committee, 2022 - Present
Member, Pharmacy & Therapeutics Committee, 2021 - Present
Associate Medical Director, Antimicrobial Stewardship Team MDACC, 2020 - Present
Honors & Awards
| 2019 | Second Place Clinical Research - Poster Session Award, Division of Internal Medicine Research Retreat - MD Anderson Cancer Center |
| 2018 | Fellow Scholarship Award, Remington Winter Course in Infectious Diseases |
| 2017 | Trainee Travel Grant Award, IDSA |
| 2014 | Most Outstanding Clinical Preceptor, New York Medical College - Metropolitan Hospital |
| 2011 | Most Outstanding PGY1, New York Medical College - Metropolitan Hospital |
| 2010 | House Physician Award, University of Miami - Jackson Memorial Hospital |
Professional Memberships
Selected Publications
Peer-Reviewed Articles
- Yibirin M, Mustafayev K, Hosry J, Pundhir P, Klingen J, Yepez Guevara E, Granwehr BP, Kaseb A, Naing A, Patel S, Shah AY, Skoulidis F, Tawbi HA, Wang L, Miller E, Zhang HC, Zurita-Saavedra A, Torres HA. Immune Checkpoint Inhibitors Suppress Hepatitis C Virus Replication in Infected Patients with Solid Tumors. American Journal of Gastroenterology, 2023. e-Pub 2023. PMID: 37307533.
- Chiu CY, Mustafayev K, Lee HC, Manasanch EE, Yepez Guevara E, Torres HA. Effect of anti-CD38 monoclonal antibodies on hepatitis C virus replication in chronically infected patients with multiple myeloma: A prospective series. Leukemia and Lymphoma, 2023. e-Pub 2023.
- Dagher H, Chaftari AM, Subbiah IM, Malek AE, Jiang Y, Lamie P, Granwehr B, John T, Yepez E, Borjan J, Reyes-Gibby C, Flores M, Khawaja F, Pande M, Ali N, Rojo R, Karp DD, Chaftari P, Hachem R, Raad II. Long COVID in cancer patients: preponderance of symptoms in majority of patients over long time period. Elife. e-Pub 2023. PMID: 36748905.
- Ariel D. Szvalb MD, Eduardo Yepez Guevara MD, Elizabeth Euscher MD, Karen A. Nahmod MD PhD, Dimitrios P. Kontoyiannis MD. Acute Peritoneal Histoplasmosis Mimicking Ovarian Cancer and Review of the Literature on Histoplasma Peritonitis. Open Forum Infectious Diseases, 2023. e-Pub 2023.
- Issam I Raad Ray Hachem Nigo Masayuki Tarcila Datoguia Hiba Dagher Ying Jiang Vivek Subbiah Bilal Siddiqui Arnaud Bayle Robert Somer Ana Fernández Cruz Edward Gorak Arvinder Bhinder Mori Nobuyoshi Nelson Hamerschlak Samuel Shelanski Tomislav Dragovich Elise Vong Suha Fakhreddine Abi Hanna Pierre Roy F Chemaly Victor Mulanovich Javier Adachi Jovan Borjan Fareed Khawaja Bruno Granwehr Teny John Eduardo Yepez Harrys Torres Natraj Reddy Ammakkanavar Marcel Yibirin Cielito Reyes-Gibby Mala Pande Noman Ali Raniv Rojo Shahnoor Ali Rita Deeba Patrick Chaftari Takahiro Matsuo Kazuhiro Ishikawa Ryo Hasegawa Ramón Aguado-Noya Alvaro García Cristina Traseira Puchol Dong-Gun Lee Monica Slavin Benjamin Teh Cesar A Arias Data-Driven Determinants for COVID-19 Oncology Discovery Effort (D3CODE) Team Prof. Dimitrios P. Kontoyiannis Alexandre E Malek Anne-Marie Chaftari. International multicenter study comparing COVID-19 in patients with cancer to patients without cancer: impact of risk factors and treatment modalities on survivorship. eLife, 2023. e-Pub 2023.
- Denise Marie A. Francisco; Liangliang Zhang; Ying Jiang; Adilene Olvera; Javier Adachi; Eduardo Yepez Guevara; Samuel L. Aitken; Kevin W. Garey; Christine B. Peterson; Kim-Anh Do; Ryan Dillon; Engels N. Obi; Robert Jenq; Pablo C. Okhuysen. Risk Factors Associated with Severe Clostridioides difficile Infection in Patients with Cancer. Infectious Diseases and Therapy, 2022.
- Yibirin M, Hosry J, Yepez Guevara E, Granwehr BP, Jiang Y, Mustafayev K, Angelidakis G, Torres HA. High sustained virologic response rate after 8 weeks of direct-acting antivirals in cancer patients with chronic hepatitis C virus. Eur J Gastroenterol Hepatol 34(10):1098-1101, 2022. e-Pub 2022. PMID: 36062500.
- Yepez Guevara EA, Aitken SL, Olvera AV, Carlin L, Fernandes KE, Bhatti MM, Garey KW, Adachi J, Okhuysen PC. Clostridioides difficile infection in cancer and immunocompromised patients: Relevance of a two-step diagnostic algorithm and infecting ribotypes on clinical outcomes. Clin Infect Dis 72(10):e460-e465, 2021. e-Pub 2020. PMID: 32803229.
- MohammedSamannodi, Reza Vaghefi-Hosseini, Masayuki Nigo, Eduardo Yepez Guevara, Rodrigo Hasbun. Risk Classification for Respiratory Viral Infections in Adult Solid Organ Transplantation Recipients. Transplantation Proceedings, 2020. e-Pub 2020. PMID: 33272649.
- Galarreta CI, Yepez E, Velez C, Aita G. [Primary T cell lymphoma of the pancreas: clinical case report]. Rev Gastroenterol Peru 32(4):423-8, 2012. PMID: 23307095.
Abstracts
- Mustafayev K, Naing A, Thomas SK, Patel KK, Pemmaraju N, Daver NG, Jiang Y, Yepez Guevara E, Torres HA. Treatment of Chronic Hepatitis C Virus Infection To Increase Access To Cancer Clinical Trials In Patients With Hematologic Malignancies: A Prospective Observational Study. The Annual Meeting of American Society of Clinical Oncology (ASCO), 2023.
- Chiu CY, Mustafayev K, Lee HC, Manasanch EE, Yepez Guevara E. Samaniego F, Torres HA. Effect of anti-CD38 monoclonal antibodies on hepatitis C virus replication in chronically infected patients with multiple myeloma: A prospective series. 18th Global Hepatitis Summit 2023, 2023.
- Alexander Franklin, Teny John, Ying Jiang, Eduardo Yepez, Kelly McConn, Fareed Khawaja, Micah Bhatti, Roy Chemaly. Discordant COVID-19 PCR results from nasopharyngeal swab and bronchoalveolar lavage at a major cancer center. ECCMID 2022 Meeting, 2022.
- Hiba Dagher, MD, Alexandre Malek, MD, Anne-Marie Chaftari, MD, Ishwaria M Subbiah, MD, Ying Jiang, MS, Peter Lamie, DO, Bruno Granwehr, MD, Teny John, MD, Eduardo Yepez Guevara, MD, Jovan Borjan, PharmD, Cielito Reyes, DRPH, Mary Flores, AA, Fareed Khawaja, MBBS, Mala Pande, MPH, PHD, Norman Ali, MD, Raniv Rojo, Daniel D Karp, MD, Ray Y Hachem, MD, Issam I Raad, MD. Long COVID in Cancer Patients: Preponderance of Symptoms in Majority of Patients Over Long Time Period. Open Forum of Infectious Diseases, 2021. e-Pub 2021.
- Hachem R, Chaftari A, Masayuki N, et al. International Multicenter Study Comparing Cancer to Non-Cancer Patients with COVID-19: Impact of Risk Factors and Treatment Modalities on Outcome. Open Forum of Infectious Diseases, 2021. e-Pub 2021.
- Yibirin M, Yepez Guevara E, Granwehr BP, Pundhir P, Torres HA. Short duration of Direct Acting Antivirals in cancer patients with chronic hepatitis C virus infection. The Liver Meeting 2020, November 13-17, 2020, 2020.
- Yibirin M, Pundhir P, Yepez Guevara E, Granwehr BP, Kaseb A, Patel S, Naing A, Shah AY, Skoulidis F, Tawbi HA, Zhang HC, Wang L, Miller E, Torres HA. SAFETY OF IMMUNE CHECKPOINT INHIBITORS IN CANCER PATIENTS WITH CHRONIC HEPATITIS C INFECTION: A PROSPECTIVE OBSERVATIONAL STUDY. The Liver Meeting 2020, November 13-17, 2020, 2020.
- Denise Francisco, Adilene Olvera, Ying Jiang, Liangliang Zhang, Eduardo Yepez Guevara, Kevin W. Garey, Christine Peterson, Kim-Anh, Ryan Dillon, Engels N. Obi, Robert Jenq, Pablo C. Okhuysen. Metronidazole Exposure Prior to Clostridiodes difficile Infection (CDI) is a Risk Factor for Severe C. difficile Disease in Cancer Patients. Open Forum Infectious Diseases, 2020.
- Olvera A, Yepez Guevara E, Garey K, Dillon R, Okhuysen P. Fecal Biomarkers for Clostridioides difficile Infection in Cancer Patients. Open Forum Infectious Diseases 6(Suppl 2):S763-S764, 2019. e-Pub 2019.
- Francisco DM, Olvera A, Zhang L, Yepez Guevara E, Garey K, Peterson C, Do K, Dillon R, Jenq R, Okhuysen P. Fecal Collinsella Abundance is Negatively Associated with Toxin A/B Production in Cancer Patients with Clostridioides difficile. Open Forum Infectious Diseases 6(Suppl 2):S821–S822, 2019. e-Pub 2019.
- Yepez Guevara Eduardo, Aitken S, Carlin L, Fernandes K, Bhatti M, Garey K, Adachi J, Okhuysen P. Clinical outcomes, bacterial loads, and markers of intestinal inflammation in immunocompromised and cancer patients with diarrhea and Clostridioides difficile identified by nucleic acid amplification tests (NAAT) and toxin A/B by enzyme immunoassay (EIA). ECCMID 2019, 2019. e-Pub 2019.
- Yepez Guevara Eduardo, Yalamanchili Harika, Chao Andrew, Garey Kevin, Bhatti Micah, Aitken Samuel, Okhuysen Pablo. Relevance of Clostridium difficile ribotype 014-20 in cancer patients with diarrhea. ECCMID 2018, 2018. e-Pub 2018.
- Yalamanchili Harika, Chao Andrew, Yepez Guevara Eduardo, Aitken Samuel, Bhatti Micah, Okhuysen Pablo. Risk Factors and Clinical Outcomes of Cancer Patients with Clostridium difficile Associated Diarrhea Co-infected with a Second Enteropathogen. Open Forum Infectious Diseases 4(Suppl 1):S362–S363, 2017. e-Pub 2017.
- Chao Andrew, Yalamanchili Harika, Yepez Guevara Eduardo, Bhatti Micah, Aitken Samuel, Okhuysen Pablo. Line of Service – Specific Performance and Antibiotic Prescribing Habits Following Introduction of a Two-Step Diagnostic Approach Using NAAT Followed by Enzyme Immunoassay in Cancer Patients with Suspected Clostridium difficile Infection. Open Forum Infectious Diseases 4(Suppl 1):S394, 2017. e-Pub 2017.
- Yepez E, Yalamanchili H, Chao A, Garey K, Bhatti M, Aitken S, Okhuysen P. Ribotypes matter. Significance of Clostridium difficile ribotypes in Cancer patients with diarrhea. Open Forum Infectious Diseases 4(Suppl 1):S386–S387, 2017. e-Pub 2017.
Book Chapters
- Yepez Guevara Eduardo, Abdel Rahman Zaid, Daher May, Mulanovich Victor Eduardo. Management of infections in HCT recipients. In: Manual of Stem Cell Transplantation and Cellular Therapies for Hematologic Malignancies. 1. ELSEVIER, 2023.
- Yepez E, Banchs J, Tweardy D, Adachi J. Infectious Endocarditis in Cancer patients. In: Cancer and the Heart. 3. People’s Medical Publishing House: USA, 477-489, 2019.
Letters to the Editor
- Pooja Pundhir, Lilian Ruth Roach, Jalen R Bartek, Rebecca P Trask, Marcel Ybirin, Eduardo Yepez Guevara, Bruno Granwehr, Crystal R Swalwel, Harrys A. Torres. Nursing practice is associated with high risk for hepatitis C virus infection. Clinical Microbiology and Infection, 2021.