Elavarasan Subramani, Ph.D.
Department of Cancer Systems Imaging, Division of Diagnostic Imaging
Present Title & Affiliation
Primary Appointment
Instructor, Department of Cancer Systems Imaging, Division of Diagnostic Imaging, The University of Texas MD Anderson Cancer Center, Houston, TX
Education & Training
Degree-Granting Education
| 2017 | Indian Institute of Technology Kharagpur, Kharagpur, IN, Medical Science and Technology, Ph.D |
Experience & Service
Faculty Academic Appointments
Research Investigator, Department of Cancer Systems Imaging, The University of Texas MD Anderson Cancer Center, Houston, TX, 2022 - 2023
Postdoctoral Scholar, Department of Cancer Systems Imaging, The University of Texas MD Anderson Cancer Center, Houston, TX, 2020 - 2022
Postdoctoral Scholar, Department of Radiology and Biomedical Imaging, The University of California San Franscisco, San Francisco, CA, 2017 - 2020
Institutional Committee Activities
Committee Member, CSI Faculty Recruitment Committee, 2024 - Present
Honors & Awards
| 2020 | Summa Cum Laude Merit Award, International Society for Magnetic Resonance in Medicine |
| 2018 - 2020 | Trainee (Educational) Stipend, International Society for Magnetic Resonance in Medicine |
| 2017 | Teaching Assistantship, Indian Institute of Technology Kharagpur |
| 2015 - 2016 | Senior Research Fellowship, Indian Institute of Technology Kharagpur |
| 2014 | Shastri Student Internship Project grant, Shastri Indo-Canadian Institute with the support of Foreign Affairs, Trade and Development, Canada |
| 2011 - 2014 | Senior Research Fellowship, Indian Council for Medical Research_IIT Kharagpur |
| 2010 - 2011 | Junior Research Fellow, Indian Institute of Technology Kharagpur |
Selected Presentations & Talks
National Presentations
- 2024. Single cell analysis reveals treatment response-associated plastic cell state and lineage switching in aggressive variant prostate cancer. Poster. AACR annual meeting. San Diego, California, US.
Grant & Contract Support
| Date: | 2024 - 2026 |
| Title: | Impact of serine restriction-mediated sphingolipid metabolism in RB-deficient aggressive prostate cancer |
| Funding Source: | NIH/NCI |
| Role: | PI |
| ID: | GRANT14002561 |
| Date: | 2024 - 2029 |
| Title: | Effects of Arginine Depletion Combined with Platinum-Taxane Chemotherapy in Aggressive Variant Prostate Cancers (AVPC) |
| Funding Source: | NIH/NCI |
| Role: | Co-I |
| ID: | R01CA283402-01A1 |
| Date: | 2024 - Present |
| Title: | Evaluation of [18F] FSPG as a biomarker of glutathione-regulated redox homeostasis and sensitivity to ferroptosis inducers in advanced prostate cancer |
| Funding Source: | MDACC |
| Role: | Co-I |
| Date: | 2023 - 2024 |
| Title: | RB as a regulator of serine and one-carbon metabolism in aggressive prostate cancer |
| Funding Source: | Prostate Cancer Foundation |
| Role: | PI |
| ID: | FP00019248 |
| Title: | Non-invasive imaging of glutathione metabolism to guide therapy for RB-deficient advanced prostate cancer |
| Funding Source: | NIH/NCI |
| Role: | PI |
| ID: | GRANT14177547 |
Selected Publications
Peer-Reviewed Articles
- Awad D, Cao PHA, Pulliam TL, Spradlin M, Subramani E, Tellman TV, Ribeiro CF, Muzzioli R, Jewell BE, Pakula H, Ackroyd JJ, Murray MM, Han JJ, Leng M, Jain A, Piyarathna B, Liu J, Song X, Zhang J, Klekers AR, Drake JM, Ittmann MM, Coarfa C, Piwnica-Worms D, Farach-Carson MC, Loda M, S Eberlin L, Frigo DE. Adipose triglyceride lipase is a therapeutic target in advanced prostate cancer that promotes metabolic plasticity. Cancer Res, 2024. e-Pub 2023. PMID: 38038968.
- Dasgupta S, Subramani E, Mitra I, Bhattacharya A, Sherpa DD, Joshi M, Chakraborty P, Ray CD, Chaudhury K. Discovery of novel metabolic signatures for early identification of women at risk of developing gestational hypertension. Metabolomics 19(5):50, 2023. e-Pub 2023. PMID: 37154845.
- Ghosh P, Bag S, Parveen S, Subramani E, Chaudhury K, Dasgupta S. Nanoencapsulation as a Promising Platform for the Delivery of the Morin-Cu(II) Complex: Antibacterial and Anticancer Potential. ACS Omega 7(9):7931-7944, 2022. e-Pub 2022. PMID: 35284762.
- Subramani E, Frigo DE. Mitochondria in Metabolic Syndrome, Reproduction and Transgenerational Inheritance-Ongoing Debates and Emerging Links. Endocrinology 162(1), 2021. e-Pub 2021. PMID: 33275660.
- Batsios G, Taglang C, Cao P, Gillespie AM, Najac C, Subramani E, Wilson DM, Flavell RR, Larson PEZ, Ronen SM, Viswanath P. Imaging 6-Phosphogluconolactonase Activity in Brain Tumors In Vivo Using Hyperpolarized δ-[1-13C]gluconolactone. Front Oncol 11:589570, 2021. e-Pub 2021. PMID: 33937017.
- Subramani E, Radoul M, Najac C, Batsios G, Molloy AR, Hong D, Gillespie AM, Santos RD, Viswanath P, Costello JF, Pieper RO, Ronen SM. Glutamate Is a Noninvasive Metabolic Biomarker of IDH1-Mutant Glioma Response to Temozolomide Treatment. Cancer Res 80(22):5098-5108, 2020. e-Pub 2020. PMID: 32958546.
- Rameshbabu AP, Bankoti K, Datta S, Subramani E, Apoorva A, Ghosh P, Jana S, Manchikanti P, Roy S, Chaudhury K, Dhara S. Bioinspired 3D porous human placental derived extracellular matrix/silk fibroin sponges for accelerated bone regeneration. Mater Sci Eng C Mater Biol Appl 113:110990, 2020. e-Pub 2020. PMID: 32487403.
- Batsios G, Najac C, Cao P, Viswanath P, Subramani E, Saito Y, Gillespie AM, Yoshihara HAI, Larson P, Sando S, Ronen SM. In vivo detection of γ-glutamyl-transferase up-regulation in glioma using hyperpolarized γ-glutamyl-[1-13C]glycine. Sci Rep 10(1):6244, 2020. e-Pub 2020. PMID: 32277103.
- Dutta M, Singh B, Joshi M, Das D, Subramani E, Maan M, Jana SK, Sharma U, Das S, Dasgupta S, Ray CD, Chakravarty B, Chaudhury K. Author Correction: Metabolomics reveals perturbations in endometrium and serum of minimal and mild endometriosis. Sci Rep 10(1):2790, 2020. e-Pub 2020. PMID: 32051518.
- Molloy AR, Najac C, Viswanath P, Lakhani A, Subramani E, Batsios G, Radoul M, Gillespie AM, Pieper RO, Ronen SM. MR-detectable metabolic biomarkers of response to mutant IDH inhibition in low-grade glioma. Theranostics 10(19):8757-8770, 2020. e-Pub 2020. PMID: 32754276.
- Batsios G, Viswanath P, Subramani E, Najac C, Gillespie AM, Santos RD, Molloy AR, Pieper RO, Ronen SM. PI3K/mTOR inhibition of IDH1 mutant glioma leads to reduced 2HG production that is associated with increased survival. Sci Rep 9(1):10521, 2019. e-Pub 2019. PMID: 31324855.
- Ghosh N, Choudhury P, Subramani E, Saha D, Sengupta S, Joshi M, Banerjee R, Roychowdhury S, Bhattacharyya P, Chaudhury K. Metabolomic signatures of asthma-COPD overlap (ACO) are different from asthma and COPD. Metabolomics 15(6):87, 2019. e-Pub 2019. PMID: 31165288.
- Najac C, Radoul M, Le Page LM, Batsios G, Subramani E, Viswanath P, Gillespie AM, Ronen SM. In vivo investigation of hyperpolarized [1,3-13C2]acetoacetate as a metabolic probe in normal brain and in glioma. Sci Rep 9(1):3402, 2019. e-Pub 2019. PMID: 30833594.
- Rameshbabu AP, Datta S, Bankoti K, Subramani E, Chaudhury K, Lalzawmliana V, Nandi SK, Dhara S. Polycaprolactone nanofibers functionalized with placental derived extracellular matrix for stimulating wound healing activity. J Mater Chem B 6(42):6767-6780, 2018. e-Pub 2018. PMID: 32254693.
- Rameshbabu AP, Bankoti K, Datta S, Subramani E, Apoorva A, Ghosh P, Maity PP, Manchikanti P, Chaudhury K, Dhara S. Silk Sponges Ornamented with a Placenta-Derived Extracellular Matrix Augment Full-Thickness Cutaneous Wound Healing by Stimulating Neovascularization and Cellular Migration. ACS Appl Mater Interfaces 10(20):16977-16991, 2018. e-Pub 2018. PMID: 29718653.
- Dutta M, Singh B, Joshi M, Das D, Subramani E, Maan M, Jana SK, Sharma U, Das S, Dasgupta S, Ray CD, Chakravarty B, Chaudhury K. Metabolomics reveals perturbations in endometrium and serum of minimal and mild endometriosis. Sci Rep 8(1):6466, 2018. e-Pub 2018. PMID: 29691425.
- Subramani E, Rameshbabu AP, Jothiramajayam M, Subramanian B, Chakravorty D, Bose G, Joshi M, Ray CD, Lodh I, Chattopadhyay R, Saha S, Mukherjee A, Dhara S, Chakravarty B, Chaudhury K. Mycobacterial heat shock protein 65 mediated metabolic shift in decidualization of human endometrial stromal cells. Sci Rep 7(1):3942, 2017. e-Pub 2017. PMID: 28638075.
- Ghosh P, Bag S, Roy AS, Subramani E, Chaudhury K, Dasgupta S. Solubility enhancement of morin and epicatechin through encapsulation in albumin based nanoparticulate system and their anticancer activity against the MDA-MB-468 breast cancer cell line. RSC Advances 6:101415, 2016. e-Pub 2016.
- Subramani E, Jothiramajayam M, Dutta M, Chakravorty D, Joshi M, Srivastava S, Mukherjee A, Ray C, Chakravarty B, Chaudhury K. NMR-based metabonomics for understanding the influence of dormant female genital tuberculosis on metabolism of the human endometrium. Human Reproduction(31(4)):854-65, 2016. e-Pub 2016. PMID: 26851602.
- Subramani E, Dutta M, Jothiramajayam M, Joshi M, Srivastava S, Mukherjee A, DattaRay C, Chakravarty B, Chaudhury K. Identification of serum metabolic markers for diagnosis of women with dormant genital tuberculosis. Metabolomics 12:99, 2016. e-Pub 2016.
- Subramani E, Madogwe E, Ray CD, Dutta SK, Chakravarty B, Bordignon V, Duggavathi R, Chaudhury K. Dysregulated leukemia inhibitory factor and its receptor regulated signal transducers and activators of transcription 3 pathway: a possible cause for repeated implantation failure in women with dormant genital tuberculosis?. Fertil Steril 105(4):1076-1084.e5, 2016. e-Pub 2016. PMID: 26776907.
- Rameshbabu AP, Ghosh P, Subramani E, Bankoti K, Kapat K, Datta S, Maity PP, Subramanian B, Roy S, Chaudhury K, Dhara S. Investigating the potential of human placenta-derived extracellular matrix sponges coupled with amniotic membrane-derived stem cells for osteochondral tissue engineering. J Mater Chem B 4(4):613-625, 2016. e-Pub 2016. PMID: 32262943.
- Dutta M, Subramani E, Taunk K, Gajbhiye A, Seal S, Pendharkar N, Dhali S, Ray CD, Lodh I, Chakravarty B, Dasgupta S, Rapole S, Chaudhury K. Mass spectrometry and bioinformatics analysis data. Data Brief 2:21-5, 2015. e-Pub 2015. PMID: 26217699.
- Dutta M, Subramani E, Taunk K, Gajbhiye A, Seal S, Pendharkar N, Dhali S, Ray CD, Lodh I, Chakravarty B, Dasgupta S, Rapole S, Chaudhury K. Investigation of serum proteome alterations in human endometriosis. J Proteomics 114:182-96, 2015. e-Pub 2015. PMID: 25449831.
- Subramani E, Basu H, Thangaraju S, Dandekar S, Mathur D, Chaudhury K. Rotational dynamics of optically trapped human spermatozoa. ScientificWorldJournal 2014:154367, 2014. e-Pub 2014. PMID: 24600321.
- Banerjee P, Ghosh S, Dutta M, Subramani E, Khalpada J, Roychoudhury S, Chakravarty B, Chaudhury K. Identification of key contributory factors responsible for vascular dysfunction in idiopathic recurrent spontaneous miscarriage. PLoS One 8(11):e80940, 2013. e-Pub 2013. PMID: 24260517.
Review Articles
- Cao PHA, Dominic A, Lujan FE, Senthilkumar S, Bhattacharya PK, Frigo DE, Subramani E. Unlocking ferroptosis in prostate cancer - the road to novel therapies and imaging markers. Nat Rev Urol, 2024. e-Pub 2024. PMID: 38627553.
- Singh A, Subramani E, Datta Ray C, Rapole S, Chaudhury K. Proteomic-driven biomarker discovery in gestational diabetes mellitus: a review. J Proteomics 127(Pt A):44-9, 2015. e-Pub 2015. PMID: 26216595.
- Thangaraju S, Subramani E, Chakravarty B, Chaudhury K. Therapeutic targeting of the TNF superfamily: a promising treatment for advanced endometrial adenocarcinoma. Gynecol Oncol 127(2):426-32, 2012. e-Pub 2012. PMID: 22885470.
Editorials
- Trajkovic-Arsic M, Subramani E. Is metabolism the magic bullet for targeted cancer therapy?. BMC Cancer 23(1):484, 2023. PMID: 37254076.
- Subramani E, Dominic A, Bhattacharya PK, Frigo DE, Bederman I, Vaziri-Gohar A. Editorial: Metabolic regulation under oxidative stress in cancer. Front Oncol 13:1286086, 2023. PMID: 37771445.
Book Chapters
- Subramani E, Banerjee P, Dattaray C, Chakrabarty D, Chakravarty B, Chaudhury K. Microscopic imaging of the endometrium for assessment of uterine receptivity in women with latent genital tuberculosis. In: Current microscopy contributions to advances in science and technology. Formatex Research Center, 186-190, 2012.
Patient Reviews
CV information above last modified July 31, 2025