Emil Schueler, Ph.D, DABR

Peer-Reviewed Articles

1. Palmiero, A, Liu, K, Colnot, J, Chopra, N, Neill, D, Connell, L, Velasquez, B, Koong, A, Lin, SH, Balter, PA, Tailor, RC, Robert, C, Germond, JF, Gonçalves Jorge, P, Geyer, R, Beddar, S, Moeckli, R, Schüler, E. On the acceptance, commissioning, and quality assurance of electron FLASH units. Medical physics 52(2):1207-1223, 2025. e-Pub 2025. PMID: 39462477.
2. Liu K, Titt U, Esplen N, Connell L, Konradsson E, Yang M, Wang X, Takaoka T, Li Z, Koong AC, Mitra D, Mohan R, Loo BW, Lin SH, Schüler E. Discordance in acute gastrointestinal toxicity between synchrotron-based proton and linac-based electron ultra-high dose rate irradiation. Int J Radiat Oncol Biol Phys, 2025. e-Pub 2025.
3. Liu, K, Holmes, SM, Khan, AU, Hooten, B, DeWerd, LA, Schüler, E, Beddar, S. Development of novel ionization chambers for reference dosimetry in electron flash radiotherapy. Medical physics 51(12):9275-9289, 2024. e-Pub 2024. PMID: 39311014.
4. Wang, J, Melemenidis, S, Manjappa, R, Viswanathan, V, Ashraf, RM, Levy, K, Skinner, L, Soto, L, Chow, S, Lau, B, Ko, RB, Graves, E, Yu, AS, Bush, K, Surucu, M, Rankin, EB, Loo, BW, Schüler, E, Maxim, PG. Dosimetric calibration of anatomy-specific ultra-high dose rate electron irradiation platform for preclinical FLASH radiobiology experiments. Medical physics 51(12):9166-9178, 2024. e-Pub 2024. PMID: 39331834.
5. Liu K, Waldrop T, Aguilar E, Mims N, Neill D, Delahoussaye A, Li Z, Swanson D, Lin SH, Koong AC, Taniguchi CM, Loo BW Jr, Mitra D, Schüler E. Redefining FLASH Radiation Therapy: The Impact of Mean Dose Rate and Dose Per Pulse in the Gastrointestinal Tract. Int J Radiat Oncol Biol Phys, 2024. e-Pub 2024. PMID: 39424078.
6. Ashraf, MR, Melemenidis, S, Liu, K, Grilj, V, Jansen, J, Velasquez, B, Connell, L, Schulz, JB, Bailat, C, Libed, A, Manjappa, R, Dutt, S, Soto, L, Lau, B, Garza, A, Larsen, W, Skinner, L, Yu, AS, Surucu, M, Graves, E, Maxim, PG, Kry, SF, Vozenin, MC, Schüler, E, Loo, BW. Multi-Institutional Audit of FLASH and Conventional Dosimetry With a 3D Printed Anatomically Realistic Mouse Phantom. International Journal of Radiation Oncology Biology Physics 120(1):287-300, 2024. e-Pub 2024. PMID: 38493902.
7. Ytterbrink, C, Shubbar, E, Parris, TZ, Langen, B, Druid, M, Schüler, E, Strand, SE, Åkerström, B, Gram, M, Helou, K, Forssell-Aronsson, E. Effects of Recombinant α1-Microglobulin on Early Proteomic Response in Risk Organs after Exposure to 177Lu-Octreotate. International journal of molecular sciences 25(13), 2024. e-Pub 2024. PMID: 39000587.
8. Liu K, Holmes S, Schüler E, Beddar S. A Comprehensive Investigation of the Performance of a Commercial Scintillator System for Applications in Electron FLASH radiotherapy. Med Phys 51(6):4504-4512, 2024. e-Pub 2024. PMID: 38507253.
9. Chang E, Wong FCL, Chasen BA, Erwin WD, Das P, Holliday EB, Koong AC, Ludmir EB, Minsky BD, Noticewala SS, Smith GL, Taniguchi CM, Rodriguez MJ, Beddar S, Martin-Paulpeter RM, Niedzielski JS, Sawakuchi GO, Schüler E, Perles LA, Xiao L, Szklaruk J, Park PC, Dasari AN, Kaseb AO, Kee BK, Lee SS, Overman MJ, Willis JA, Wolff RA, Tzeng CD, Vauthey JN, Koay EJ. Phase I trial of single-photon emission computed tomography-guided liver-directed radiotherapy for patients with low functional liver volume. JNCI Cancer Spectr 8(3), 2024. e-Pub 2024. PMID: 38730548.
10. Baikalov A, Tho D, Liu K, Bartzsch S, Beddar S, Schüler E. Characterization of a novel time-resolved, real-time scintillation dosimetry system for ultra-high dose rate radiation therapy applications. Int J Radiat Oncol Biol Phys, 2024. e-Pub 2024.
11. Ko RB, Abelson JA, Fleischmann D, Louie JD, Hwang GL, Sze DY, Schüler E, Kielar KN, Maxim PG, Le QT, Hara WH, Diehn M, Kothary N. Pulmonary interstitial lymphography: A prospective trial with potential impact on stereotactic ablative radiotherapy planning for early-stage lung cancer. Radiother Oncol 191, 2024. e-Pub 2024. PMID: 38163486.
12. Liu, K, Holmes, SM, Hooten, B, Schüler, E, Beddar, S. Evaluation of ion chamber response for applications in electron FLASH radiotherapy. Med Phys 51(1):494-508, 2024. e-Pub 2024. PMID: 37696271.
13. Liu K, Velasquez B, Schüler E. Technical note: High-dose and ultra-high dose rate (UHDR) evaluation of Al2O3:C optically stimulated luminescent dosimeter nanoDots and powdered LiF:Mg,Ti thermoluminescent dosimeters for radiation therapy applications. Med Phys 51(3):2311-2319, 2023. e-Pub 2023. PMID: 7991111.
14. Liu, K, Jorge, PG, Tailor, RC, Moeckli, R, Schüler, E. Comprehensive evaluation and new recommendations in the use of Gafchromic EBT3 film. Med Phys 50(11):7252-7262, 2023. e-Pub 2023. PMID: 37403570.
15. No, HJ, Wu, Y, Dworkin, ML, Manjappa, R, Skinner, L, Ashraf, MR, Lau, B, Melemenidis, S, Viswanathan, V, Yu, AS, Surucu, M, Schüler, E, Graves, E, Maxim, PG, Loo, BW. Clinical Linear Accelerator-Based Electron FLASH. Int J Radiat Oncol Biol Phys 117(2):482-492, 2023. e-Pub 2023. PMID: 37105403.
16. Abolfath R, Baikalov A, Fraile A, Bartzsch S, Schüler E, Mohan R. A stochastic reaction-diffusion modeling investigation of FLASH ultra-high dose rate response in different tissues. Front. Phys, 2023. e-Pub 2023.
17. Liu, L, Shen, L, Yang, Y, Schüler, E, Zhao, W, Wetzstein, G, Xing, L. Modeling linear accelerator (Linac) beam data by implicit neural representation learning for commissioning and quality assurance applications. Med Phys 50(5):3137-3147, 2023. e-Pub 2023. PMID: 36621812.
18. Valdés Zayas, A, Kumari, N, Liu, K, Neill, D, Delahoussaye, AM, Gonçalves Jorge, P, Geyer, R, Lin, SH, Bailat, C, Bochud, F, Moeckli, R, Koong, A, Bourhis, J, Taniguchi, C, Herrera, FG, Schüler, E. Independent Reproduction of the FLASH Effect on the Gastrointestinal Tract. Cancers 15(7), 2023. e-Pub 2023. PMID: 37046782.
19. Liu, K, Palmiero, A, Chopra, N, Velasquez, B, Li, Z, Beddar, S, Schüler, E. Dual beam-current transformer design for monitoring and reporting of electron ultra-high dose rate (FLASH) beam parameters. J Appl Clin Med Phys 24(2), 2023. e-Pub 2023. PMID: 36601691.
20. Baikalov, A, Abolfath, RM, Schüler, E, Mohan, R, Wilkens, JJ, Bartzsch, S. Intertrack interaction at ultra-high dose rates and its role in the FLASH effect. Front. Phys 11, 2023. e-Pub 2023.
21. Jorge, PG, Melemenidis, S, Grilj, V, Buchillier, T, Manjappa, R, Viswanathan, V, Gondré, M, Vozenin, MC, Germond, JF, Bochud, F, Moeckli, R, Limoli, C, Skinner, L, No, HJ, Wu, YF, Surucu, M, Yu, AS, Lau, B, Wang, J, Schüler, E, Bush, K, Graves, E, Maxim, PG, Loo, BW, Bailat, C. Design and validation of a dosimetric comparison scheme tailored for ultra-high dose-rate electron beams to support multicenter FLASH preclinical studies. Radiother Oncol 175:203-209, 2022. e-Pub 2022. PMID: 36030934.
22. Thrower, SL, Prajapati, S, Holmes, SM, Schüler, E, Beddar, S. Characterization of the Plastic Scintillator Detector System Exradin W2 in a High Dose Rate Flattening-Filter-Free Photon Beam. Sensors 22(18), 2022. e-Pub 2022. PMID: 36146135.
23. Yang, M, Wang, X, Guan, F, Titt, U, Iga, K, Jiang, D, Takaoka, T, Tootake, S, Katayose, T, Umezawa, M, Schüler, E, Frank, SJ, Lin, SH, Sahoo, N, Koong, A, Mohan, R, Zhu, XR. Adaptation and dosimetric commissioning of a synchrotron-based proton beamline for FLASH experiments. Phys Med Biol 67(16), 2022. e-Pub 2022. PMID: 35853442.
24. Zhao, W, Yang, Y, Xing, L, Chuang, CF, Schüler, E. Mitigating the uncertainty in small field dosimetry by leveraging machine learning strategies. Phys Med Biol 67(15), 2022. e-Pub 2022. PMID: 35803256.
25. Titt U, Yang M, Wang X, Iga K, Fredette N, Schüler E, Lin SH, Zhu XR, Sahoo N, Koong AC, Zhang X, Mohan R. Design and validation of a synchrotron proton beam line for FLASH radiotherapy preclinical research experiments. Med Phys 49(1):497-509, 2022. e-Pub 2022. PMID: 34800037.
26. Kim YE, Gwak SH, Hong BJ, Oh JM, Choi HS, Kim MS, Oh D, Lartey FM, Rafat M, Schüler E, Kim HS, von Eyben R, Weissman IL, Koch CJ, Maxim PG, Loo BW, Ahn GO. Effects of Ultra-high doserate FLASH Irradiation on the Tumor Microenvironment in Lewis Lung Carcinoma: Role of Myosin Light Chain. Int J Radiat Oncol Biol Phys 109(5):1440-1453, 2021. e-Pub 2021. PMID: 33186615.
27. Turner BE, Schüler E, Chang SD, Harsh GR, Soltys SG. Intracranial Autograft Fat Placement to Separate the Optic Chiasm from Tumor to Improve Stereotactic Radiotherapy Dosimetry. World Neurosurg. World Neurosurgery 146:80-84, 2021. e-Pub 2021. PMID: 33130141.
28. Levy K, Natarajan S, Wang J, Chow S, Eggold JT, Loo PE, Manjappa R, Melemenidis S, Lartey FM, Schüler E, Skinner L, Rafat M, Ko R, Kim A, H Al-Rawi D, von Eyben R, Dorigo O, Casey KM, Graves EE, Bush K, Yu AS, Koong AC, Maxim PG, Loo BW, Rankin EB. Abdominal FLASH irradiation reduces radiation-induced gastrointestinal toxicity for the treatment of ovarian cancer in mice. Sci Rep 10(1):21600, 2020. e-Pub 2020. PMID: 33303827.
29. Schüler E, Mallozzi R, Levy J, Hristov D. Technical Note: Extended field-of-view (FOV) MRI distortion determination through multi-positional phantom imaging. J Appl Clin Med Phys 21(11):322-332, 2020. e-Pub 2020. PMID: 33073909.
30. Zhao W, Patil I, Han B, Yang Y, Xing L, Schüler E. Beam data modeling of linear accelerators (linacs) through machine learning and its potential applications in fast and robust linac commissioning and quality assurance. Radiother Oncol(153):122-129, 2020. e-Pub 2020. PMID: 33039427.
31. Kim AS, Melemenidis S, Gustavsson AK, Abid D, Wu Y, Liu F, Hristov D, Schüler E. Increased local tumor control through nanoparticle-mediated, radiation-triggered release of nitrite, an important precursor for reactive nitrogen species. Phys Med Biol 65(19):195003, 2020. e-Pub 2020. PMID: 32721936.
32. Gao P, Cheng K, Schüler E, Jia M, Zhao W, Xing L. Restarted primal-dual Newton conjugate gradient method for enhanced spatial resolution of reconstructed cone-beam x-ray luminescence computed tomography images. Phys Med Biol 65(13):135008, 2020. e-Pub 2020. PMID: 32268318.
33. Schüler E, Lo A, Chuang CF, Soltys SG, Pollom EL, Wang L. Clinical impact of the VOLO optimizer on treatment plan quality and clinical treatment efficiency for CyberKnife. J Appl Clin Med Phys 21(5):38-47, 2020. e-Pub 2020. PMID: 32212374.
34. Andersson CK, Shubbar E, Schüler E, Åkerström B, Gram M, Forssell-Aronsson EB. Recombinant α1-Microglobulin Is a Potential Kidney Protector in 177Lu-Octreotate Treatment of Neuroendocrine Tumors. J Nucl Med 60(11):1600-1604, 2019. e-Pub 2019. PMID: 30926650.
35. Simmons DA, Lartey FM, Schüler E, Rafat M, King G, Kim A, Ko R, Semaan S, Gonzalez S, Jenkins M, Pradhan P, Shih Z, Wang J, von Eyben R, Graves EE, Maxim PG, Longo FM, Loo BW. Reduced cognitive deficits after FLASH irradiation of whole mouse brain are associated with less hippocampal dendritic spine loss and neuroinflammation. Radiother Oncol 139:4-10, 2019. e-Pub 2019. PMID: 31253467.
36. Schüler E, Wang L, Loo BW, Maxim PG. Conical beam geometry intensity-modulated radiation therapy. Phys Med Biol 64(12):125014, 2019. e-Pub 2019. PMID: 31125980.
37. Spetz J, Rudqvist N, Langen B, Parris TZ, Dalmo J, Schüler E, Wängberg B, Nilsson O, Helou K, Forssell-Aronsson E. Time-dependent transcriptional response of GOT1 human small intestine neuroendocrine tumor after 177Lu[Lu]-octreotate therapy. Nucl Med Biol 60:11-18, 2018. e-Pub 2018. PMID: 29502008.
38. Schüler E, Eriksson K, Hynning E, Hancock SL, Hiniker SM, Bazalova-Carter M, Wong T, Le QT, Loo BW, Maxim PG. Very high-energy electron (VHEE) beams in radiation therapy; Treatment plan comparison between VHEE, VMAT, and PPBS. Med Phys 44(6):2544-2555, 2017. e-Pub 2017. PMID: 28339108.
39. Rudqvist N, Spetz J, Schüler E, Parris TZ, Langen B, Helou K, Forssell-Aronsson E. Transcriptional response to 131I exposure of rat thyroid gland. PLoS One 12(2):e0171797, 2017. e-Pub 2017. PMID: 28222107.
40. Schüler E, Trovati S, King G, Lartey F, Rafat M, Villegas M, Praxel AJ, Loo BW, Maxim PG. Experimental Platform for Ultra-high Dose Rate FLASH Irradiation of Small Animals Using a Clinical Linear Accelerator. Int J Radiat Oncol Biol Phys 97(1):195-203, 2017. e-Pub 2017. PMID: 27816362.
41. MaierEmail A, Westphal S, Geimer T, Maxim PG, King G, Schüler E, Fahrig R, Loo B. Fast Pose Verification for High-Speed Radiation Therapy. Bildverarbeitung für die Medizin:104 - 109, 2017. e-Pub 2017.
42. Rudqvist N, Spetz J, Schüler E, Langen B, Parris TZ, Helou K, Forssell-Aronsson E. Gene expression signature in mouse thyroid tissue after (131)I and (211)At exposure. EJNMMI Res 5(1):59, 2015. e-Pub 2015. PMID: 26492889.
43. Schüler E, Larsson M, Parris TZ, Johansson ME, Helou K, Forssell-Aronsson E. Potential Biomarkers for Radiation-Induced Renal Toxicity following 177Lu-Octreotate Administration in Mice. PLoS One 10(8):e0136204, 2015. e-Pub 2015. PMID: 26287527.
44. Schüler E, Österlund A, Forssell-Aronsson E. The amount of injected 177Lu-octreotate strongly influences biodistribution and dosimetry in C57BL/6N mice. Acta Oncol 55(1):68-76, 2015. e-Pub 2015. PMID: 25813472.
45. Rudqvist N, Schüler E, Parris TZ, Langen B, Helou K, Forssell-Aronsson E. Dose-specific transcriptional responses in thyroid tissue in mice after (131)I administration. Nucl Med Biol 42(3):263-8, 2015. e-Pub 2015. PMID: 25496975.
46. Langen B, Rudqvist N, Parris TZ, Schüler E, Helou K, Spetz J, Forssell-Aronsson E. Transcriptional response in normal mouse tissues after i.v. 211At administration - response related to absorbed dose, dose rate, and time. EJNMMI Res(5):1, 2015. e-Pub 2015. PMID: 25853007.
47. Rudqvist N, Spetz J, Schüler E, Parris TZ, Langen B, Helou K, Forssell-Aronsson E. Transcriptional Response in Mouse Thyroid Tissue after (211) At Administration: Effects of Absorbed Dose, Initial Dose-Rate and Time after Administration. PLoS One 10(7):e0131686, 2015. e-Pub 2015. PMID: 26177204.
48. Schüler E, Rudqvist N, Parris TZ, Langen B, Spetz J, Helou K, Forssell-Aronsson E. Time- and dose rate-related effects of internal (177)Lu exposure on gene expression in mouse kidney tissue. Nucl Med Biol 41(10):825-32, 2014. e-Pub 2014. PMID: 25156037.
49. Schüler E, Rudqvist N, Parris TZ, Langen B, Helou K, Forssell-Aronsson E. Transcriptional response of kidney tissue after 177Lu-octreotate administration in mice. Nucl Med Biol 41(3):238-47, 2014. e-Pub 2014. PMID: 24434014.
50. Schüler E, Parris TZ, Helou K, Forssell-Aronsson E. Distinct microRNA expression profiles in mouse renal cortical tissue after 177Lu-octreotate administration. PLoS One 9(11):e112645, 2014. e-Pub 2014. PMID: 25386939.
51. Schüler E, Gustavsson AK, Hertenberger S, Sattler K. Solar photocatalytic and electrokinetic studies of TiO2/Ag Nanoparticle suspensions. Solar Energy 96:220-226, 2013. e-Pub 2013.
52. Langen B, Rudqvist N, Parris TZ, Schüler E, Helou K, Forssell-Aronsson E. Comparative analysis of transcriptional gene regulation indicates similar physiologic response in mouse tissues at low absorbed doses from intravenously administered 211At. J Nucl Med 54(6):990-8, 2013. e-Pub 2013. PMID: 23658216.
53. Rudqvist N, Parris TZ, Schüler E, Helou K, Forssell-Aronsson E. Transcriptional response of BALB/c mouse thyroids following in vivo astatine-211 exposure reveals distinct gene expression profiles. EJNMMI Res 2(1):32, 2012. e-Pub 2012. PMID: 22697397.
54. Schüler E, Parris TZ, Rudqvist N, Helou K, Forssell-Aronsson E. Effects of internal low-dose irradiation from 131I on gene expression in normal tissues in Balb/c mice. EJNMMI Res 1(1):29, 2011. e-Pub 2011. PMID: 22214497.

Other Articles

1. Tobias Böhlen, T, Psoroulas, S, Aylward, JD, Beddar, S, Douralis, A, Delpon, G, Garibaldi, C, Gasparini, A, Schüler, E, Stephan, F, Moeckli, R, Subiel, A Recording and reporting of ultra-high dose rate “FLASH” delivery for preclinical and clinical settings. Radiotherapy and Oncology 200, 2024. PMID: 39245070.
2. Loo, BW, Verginadis, II, Sørensen, BS, Mascia, AE, Perentesis, JP, Koong, A, Schüler, E, Rankin, EB, Maxim, PG, Limoli, C, Vozenin, MC Navigating the Critical Translational Questions for Implementing FLASH in the Clinic. Seminars in radiation oncology 34(3):351-364, 2024. PMID: 38880544.
3. Zou, W, Zhang, R, Schüler, E, Taylor, PA, Mascia, AE, Diffenderfer, ES, Zhao, T, Ayan, AS, Sharma, M, Yu, SJ, Lu, W, Bosch, WR, Tsien, C, Surucu, M, Pollard-Larkin, JM, Schuemann, J, Moros, EG, Bazalova-Carter, M, Gladstone, DJ, Li, H, Simone, C, Petersson, K, Kry, SF, Maity, A, Loo, BW, Dong, L, Maxim, PG, Xiao, Y, Buchsbaum, J Framework for Quality Assurance of Ultrahigh Dose Rate Clinical Trials Investigating FLASH Effects and Current Technology Gaps. Int J Radiat Oncol Biol Phys 116(5):1202-1217, 2023. PMID: 37121362.
4. Okoro CM, Schüler E, Taniguchi CM The Therapeutic Potential of FLASH-RT for Pancreatic Cancer. Cancers (Basel) 14(5), 2022. PMID: 35267474.
5. Schüler E, Acharya M, Montay-Gruel P, Loo BW, Vozenin MC, Maxim PG Ultra-high dose rate electron beams and the FLASH effect: From preclinical evidence to a new radiotherapy paradigm. Med Phys 49(3):2082-2095, 2022. PMID: 34997969.
6. Wu Y, No HJ, Breitkreutz DY, Mascia AE, Moeckli R, Bourhis J, Schüler E, Maxim PG, Loo BW Technological Basis for Clinical Trials in FLASH Radiation Therapy: A Review. Applied Radiation Oncology 10(2):6-14, 2021.
7. Forssell-Aronsson, E, Schüler, E, Ahlman, H Advances in the diagnostic imaging of pheochromocytomas. Reports in Med Imaging 4:19-27, 2011.

Abstracts

1. Xu Q, Toesca D, Vitzthum L, Jamalian A, Schüler E, Alkim E, Baclay J, Chang DT, Gevaert O, Fisher Jr GA, Itakura H. Clinic-radiographic predictors of overall survival in stage II-III pancreatic cancer. American Society of Clinical Oncology (ASCO).
2. Emil Schüler, Parris T.Z., Rudqvist N, Helou K, Forssell-Aronsson E. Effects on gene expression in normal mouse tissues following low dose 131I irradiation. International Congress of Radiation Research.
3. Rudqvist N, Parris TZ, Schüler E, Helou K, Forssell-Aronsson E. In vivo astatine-211 exposure reveals distinct absorbed dose-dependent gene expression profiles in mouse thyroid tissue. 14th International Congress of Radiation Research.
4. Schüler E, Parris TZ, Rudqvist N, Helou K, Forssell-Aronsson E. Effects of low dose 131I irradiation on gene expression in normal mouse tissues. European association of nuclear medicine.
5. Rudqvist N, Parris TZ, Schüler E, Helou K, Forssell-Aronsson E. Transcriptional response of mouse thyroids following in vivo Astatine-211 exposure reveals distinct gene expression profiles. 24th Annual Congress on European Association of Nuclear Medicine.
6. Rudqvist N, Parris TZ, Schüler E, Helou K, Forssell-Aronsson E. The transcriptional response to in vivo astatine-211 exposure of mouse thyroids reveals distinct absorbed dose-dependent profiles. From Dosimetry to Biological Effect: Radiobiology as Guide to Clinical Practice in Nuclear Medicine.
7. Schüler E, Parris TZ, Rudqvist N, Helou K, Forssell-Aronsson E. Global transcriptional response on mouse kidney following internal irradiation with 177Lu-octreotate. Nuclear medicine discoveries.
8. Schüler E, Parris TZ, Rudqvist N, Helou K, Forssell-Aronsson E. Biological effects on normal tissues following low dose 131I irradiation; microarray and gene expression analysis. Nuclear medicine discoveries.
9. Rudqvist N, Parris TZ, Schüler E, Helou K, Forssell-Aronsson E. In Vivo Iodine-131 Exposure Reveals Distinct Absorbed Dose-dependent Gene Expression Profiles in Mouse Thyroid Tissue. From Dosimetry to Biological Effect: Radiobiology as Guide to Clinical Practice in Nuclear Medicine.
10. Schüler E, Rudqvist N, Parris TZ, Helou K, Forssell-Aronsson E. Distinct gene expression response in kidney tissue after injection with 177Lu-octreotat. Society of Nuclear Medicine.
11. Schüler E, Rudqvist N, Parris TZ, Langen B, Helou K, Forssell-Aronsson E. Dose-rate related effects on gene expression in kidney tissue after intravenous injection of 177LuCl3 in mouse. European Association of Nuclear Medicine.
12. Larsson M, Schüler E, Parris TZ, Rudqvist N, Helou K, Ahlman H, Forssell-Aronsson E. Kidney toxicity in mice treated with 177Lu-[DOTA0, Tyr3]-octreotate. European Association of Nuclear Medicine.
13. Rudqvist N, Schüler E, Parris TZ, Langen B, Helou K, Forssell-Aronsson E. 211At exposure of Balb/c mice in vivo resulted in distinct biological effects on thyroid at 1, 6 hours and 7 days after injection. Radiation Research Society.
14. Langen B, Rudqvist N, Parris TZ, Schüler E, Helou K, Forssell-Aronsson E. I.V. administration of astatine-211 results in tissue-specific transcriptional gene regulation at low absorbed doses in mouse. European Association of Nuclear Medicine.
15. Schüler E, Rudqvist N, Parris TZ, Langen B, Helou K, Forssell-Aronsson E. Biological effects of 177Lu-octreotate therapy in mouse: in vivo normal kidney tissue response evaluated with gene expression microarray. Radiation Research Society.
16. Rudqvist N, Schüler E, Parriz TZ, Langen B, Helou K, Forssell-Aronsson E. Balb/c Mice Thyroids Revealed Distinct Effects On Gene Expression At 1, 6 Hours And 7 Days After Injection Of Exposure To Astatine-211. European Association of Nuclear Medicine.
17. Langen B, Rudqvist N, Parris TZ, Schüler E, Helou K, Forssell-Aronsson E. Transcriptional gene regulation in abdominal organs and the lung after i.v. injection of 211At in mouse. Radiation Research Society.
18. Langen B, Rudqvist N, Parris TZ, Schüler E, Helou K, Forssell-Aronsson E. Similarities and differences in transcriptional responses between mouse tissues after i.v. injection of 211At. The 1st Joint BioCARE, StratCan and UCan Cancer Research Meeting.
19. Langen B, Rudqvist N, Parris TZ, Schüler E, Helou K, Forssell-Aronsson E. Relevance of systemic physiological aspects for radionuclide exposure. Systems Biology Meeting.
20. Rudqvist N, Langen B, Schüler E, Parris TZ, Helou K, Forssell-Aronsson E. Radiation-induced transcriptional response in kidneys, liver, lungs, spleen and thyroid in mice exposed to 211At. Radiobiology Applied to Oncology.
21. Forssell-Aronsson E, Rudqvist N, Langen B, Parris TZ, Schüler E, Helou K. Transcriptional effects on normal tissues after administration of 211At in mice. 8th International Symposium of Targeted Alpha Therapy.
22. Langen B, Rudqvist N, Parriz TZ, Schüler E, Helou K, Forssell-Aronsson E. Short-term study of transcriptional regulation following low-dose astatine-211 exposure in mouse. Society of Nuclear Medicine and Molecular Imaging.
23. Langen B, Rudqvist N, Parriz TZ, Schüler E, Spetz J, Helou K Forssell-Aronsson E. Early transcriptional regulation following low-activity 211At exposure in mouse and related systemic physiological aspects. SWE-RAYS.
24. Rudqvist N, Langen B, Schüler E, Parris TZ, Helou K, Forssell-Aronsson E. Radiation-induced transcriptional response in mouse thyroid and systemic effects on liver, lungs, kidney, and spleen. SWE-RAYS.
25. Schüler E, Rudqvist N, Parris TZ, Langen B, Helou K, Forssell-Aronsson E. Dose-rate effects in radionuclide therapy: global transcriptional regulation in kidney tissue in vivo after 177LuCl3 administration. SWE-RAYS.
26. Rudqvist N, Langen B, Schüler E, Parris TZ, Helou K, Forssell-Aronsson E. Radiation-induced transcriptional response in kidneys, liver, lungs, spleen, and thyroid in mice exposed to 211At. Radiation Research Society (RRS).
27. Schüler E, Rudqvist N, Parris TZ, Langen B, Helou K, Forssell-Aronsson E. Dose-rate effects in radionuclide therapy: global transcriptional regulation in kidney tissue in vivo after 177LuCl3 administration. Radiation Research society (RRS).
28. Forssell-Aronsson E, Rudqvist N, Langen B, Parriz TZ, Schüler E, Helou K. Transcriptional effects on normal tissues after administration of 211At in mice. Fifth International MELODI Workshop.
29. Forssell-Aronsson E, Rudqvist N, Langen B, Parriz TZ, Schüler E, Helou K. Radiobiologiska effekter på thyroidea efter exponering för 211At och 131I. Strålsäkerhetsmyndighetens forskningsdagar.
30. Schüler E, Larsson M, Parris TZ, Helou K, Forssell-Aronsson E. Kidney toxicity profiles after 177Lu-octreotate administration. SWE-RAYS.
31. Schüler E, Parris TZ, Helou K, Forssell-Aronsson E. Micro-RNA signature of 177Lu-octreotate treatment effects in renal cortical tissue. Cancerfondens planeringsgrupp för radionuklidterapi.
32. Rudqvist N, Langen B, Schüler E, Parris TZ, Helou K, Forssell-Aronsson E. Radiation-induced transcriptional response in thyroid tissue change with time in mice exposed to 211At. Cancerfondens planeringsgrupp för radionuklidterap.
33. Rudqvist N, Spetz J, Parris TZ, Langen B, Schüler E, Helou K, Forssell-Aronsson E. Relationship between transcriptional regulation profiles of 27 genes commonly regulated in mice after 131I and 211At exposure. SWE-RAYS.
34. Rudqvist N, Parris TZ, Langen B, Schüler E, Spetz J, Helou K, Forssell-Aronsson E. Genetic signatures detected in thyroid tissue in mice after 131I and 211At exposure. Radiation Research Society.
35. Schüler E, Larsson M, Parris TZ, Helou K, Forssell-Aronsson E. Radiation-induced renal toxicity from 177Lu-octreotate: long term effects and biomarker development. Radiation Research Society.
36. Rudqvist N, Spetz J, Parris TZ, Langen B, Schüler E, Helou K, Forssell-Aronsson E. Transcriptional relationships and biological functions of 27 genes commonly regulated in thyroid tissue in mice after 131I and 211At. European Association of Nuclear Medicine.
37. Schüler E, Larsson M, Parris TZ, Helou K, Forssell-Aronsson E. 177Lu-octreotate therapy and renal toxicity: novel biomarkers predicting absorbed dose. European Association of Nuclear Medicine.
38. Larsson M, Österlund A, Schüler E, Forssell-Aronsson E. Kidney protection in normal mice injected with 111In-octreotide using lysine and DMSA. European Association of Nuclear Medicine.
39. Schüler E, Larsson M, Parris TZ, Johansson ME, Helou K, Forssell-Aronsson E. 177Lu-octreotate therapy: transcriptional, functional, and morphological evaluation at late time-points in mouse kidney. Cancerfondens planeringsgrupp för radionuklidterapi.
40. Spetz J, Langen B, Parris TZ, Schüler E, Swanpalmer J, Wangberg B, Nilsson O, Helou K, Forssell-Aronsson E. Transcriptomic effects on GOT2 tumors in nude mice – comparison between 177Lu-octreotate and external beam therapy. Cancerfondens planeringsgrupp för radionuklidterapi.
41. Rudqvist N, Spetz J, Parris TZ, Schüler E, Langen B, Helou K, Forssell-Aronsson E. Radiation induced transcriptional response in thyroid tissue change with time in mice exposed to 211At. Cancerfondens planeringsgrupp för radionuklidterapi.
42. Rudqvist N, Spetz J, Schüler E, Parris TZ, Langen B, Helou K, Forssell-Aronsson E. Identification of Dbp as a candidate biomarker gene of low-level 131I exposure that affects thyroid function. 15th International Congress of Radiation Research.
43. Schüler E, Dalmo J, Larsson M, Parris TZ, Helou K, Forssell-Aronsson E. Proteomic response of kidney cortex after 177Lu-octreotate administration: correlation with functional and morphological effects. 15th International Congress of Radiation Research.
44. Schüler E, Larsson M, Parris TZ, Johansson M, Helou K, Forssell-Aronsson E. Long-term renal effects following 177Lu-octreotate therapy: novel biomarkers predicting absorbed dose. 15th International Congress of Radiation Research.
45. Schüler E, Parris TZ, Helou K, Forssell-Aronsson E. MicroRNA signature of 177Lu-octreotate treatment effects in renal cortical tissue. 15th International Congress of Radiation Research.
46. Romiani A, Spetz J, Schüler E, Forssell-Aronsson E. Binding and internalization of 177Lu-octreotate in two neuroblastoma cell lines and initial biodistribution studies in animals. The Swedish Cancer Society’s planning group for Oncological Radiotherapy.
47. Schüler E, Trovati S, King G, Lartey L, Rafat M, Loo Jr BW, Maxim PG. FLASH irradiation improves the therapeutic index following GI tract irradiation. American Association for Physicists in Medicine (AAPM).
48. Schüler E, Eriksson K, Hynning E, Loo Jr BW, Maxim PG. Evaluation of very high-energy electron (VHEE) beams in comparison to VMAT and PBS treatment plans. American Association for Physicists in Medicine (AAPM).
49. Trovati S, Borchard P, King G, Limborg C, Loo Jr BW, Maxim PG, McCormick D, Nicolas L, Schüler E, Tantawi S, Wang J, Wang L. Validation of a novel therapeutic X-ray array source and collimation system. American Association for Physicists in Medicine (AAPM).
50. Schüler E, Trovati S, King G, Lartey F, Rafat M, Loo Jr BW, Maxim PG. Decreased normal tissue toxicity in the Gi tract in mice irradiated with FLASH vs conventional dose rates. Radiation Research Society.
51. Lartey F, Simmons D, Schüler E, Rafat M, King G, Pradhan P, Jenkins M, Semaan S, Graves E, Maxim PG, Loo Jr BW. FLASH, a new paradigm in radiotherapy – Implications for cognitive behavior and neuroinflammation. Radiation Research Society.
52. Loo Jr BW, Schüler E, Lartey F, Rafat M, King G, Trovati S, Koong AC, Maxim PG. Delivery of Ultra-Rapid Flash Radiation Therapy and Demonstration of Normal Tissue Sparing After Abdominal Irradiation of Mice. ARS 99th Annual Meeting.
53. Trovati S, Schüler E, King G, Hynning E, Loo Jr BW, Maxim PG. A Method for the Generation of Treatment Plans for a Novel X-Ray Target and Collimation System (SPHINX). American Association for Physicists in Medicine (AAPM).
54. Schüler E, Loo Jr BW, Maxim PG. Conical Beam Geometry in Radiation Therapy. American Association for Physicists in Medicine (AAPM).
55. Ross J, Schüler E, Ko R, Bush K, Maxim P, Gensheimer M, Jr B, Diehn AM. Radiologic Quantification and Predictors of Lung Fibrosis After Stereotactic Ablative Radiotherapy (SABR). American Society for Radiation Oncology (ASTRO).
56. Schüler E, Mallozi R, Hristov D. MRI distortion visualization in radiation therapy. American Association for Physicists in Medicine (AAPM),.
57. Schüler E, Wang L, Loo Jr BW, Maxim PG. Feasibility of a novel conical beam arrangement in radiation therapy. American Association for Physicists in Medicine (AAPM),.
58. Andersson C, Shubbar E, Schüler E, Åkerström B, Gram M, Forssell-Aronsson E. The protective antioxidant rA1M allows full antitumor effects of 177Lu-octreotate treatment in PDX neuroendocrine tumor models. Gothenburg Cancer Meeting.
59. Levy K, Rafat M, Schüler E, Eggold JT, Wang J, Casey K, Koong A, Maxim P, Loo BW, Rankin E. Preclinical Testing of Ultra-rapid FLASH Total Abdominal Irradiation Demonstrates Survival Benefit and Decreased Gastrointestinal Toxicity Compared to Conventional External Beam Radiation. American Society of Clinical Oncology (ASCO).
60. Itakura H, Ikeda D, Okamoto S, Chen ST, Rister B, Gude D, Mattonen S, Alkim E, Todderud J, Schüler E, Rubin D, Sledge Jr GW, Kurian A. Radiomics Features Identify Three Distinct Subtypes of Triple-Negative Breast Cancers. American Society of Clinical Oncology (ASCO).
61. Schüler E, Lo A, Chuang C, Soltys S, Wang L. The Stanford experience with Precision 2.0 and the VOLO optimizer. American Association for Physicists in Medicine (AAPM).
62. Schüler E, Mallozi R, Levy J, Gerdes J, Hristov D. Extended Field-of-View (FOV) MRI distortion determination through combining multi-positional phantom imaging. American Association for Physicists in Medicine (AAPM).
63. Schüler E, Zhao W, Patil I, Han B, Yang Y, Xing L. Machine learning modeling of beam data of multiple linear accelerators (LINACs) from different institutions and its practical application in fast and robust LINAC commissioning. American Association for Physicists in Medicine (AAPM).
64. Zhao W, Schüler E, Patil I, Han B, Yang Y, Xing L. Harnessing the power of machine learning for accurate and efficient linear accelerator beam data commissioning. American Society for Radiation Oncology (ASTRO).
65. Ross JB, Merriott DJ, Alhumaid S, Schüler E, Ko R, Bush K, Maxim P G, Gensheimer MF, Loo Jr BW, and Diehn M. Influence of Dose and Fractionation on Radiologic Lung Fibrosis After Stereotactic Ablative Radiotherapy (SABR). American Society for Radiation Oncology (ASTRO).
66. Cheng K, Schüler E, Dai X, Zhao W, Sivasubramanian K, Jia M, Xing L. Radiation Activatable Radiosensitizers for Image Guided and Enhanced Radiation Therapy against Head and Neck Cancer. American Society for Radiation Oncology (ASTRO).
67. Andersson C, Shubbar E, Schüler E, Åkerström B, Gram M, Forssell-Aronsson E. rA1M, a kidney protector during PRRT?. European Radiation Protection Week 2019.
68. Shumail M, Nantista C D, J Wang J, Manjappa R, Li Z, Bowden G B, Wang J, Tantawi S G, Schüler E, Bush K, Yu A S, Loo B W, Maxim P G. Design of a PHASER Linac System and Target for Monochromatic and High Average Power Radiation for Rapid and Precise Radiotherapy. American Nuclear Society. International Topical Meeting on Nuclear Applications of Accelerators.
69. Zhao W, Chuang C, Yang Y, Xing L, Schüler E. Leveraging Machine Learning Strategies for Reduced Uncertainty in Small Field Dosimetry. American Association for Physicists in Medicine.
70. Vasudevan V, Huang C, Simiele E, Yu L, Xing L, Schüler E. Combining Monte Carlo with a Generative Adversarial Network to Predict High-Resolution Low-Noise Dose Distributions. American Association of Physicists in Medicine.
71. Schüler E, Kim AS, Melemenidis S, Gustavsson AK, Abid D, Wu Y, Liu F, Hristov D. Increased Local Tumor Control Through Nanoparticle-Mediated, Radiation-Triggered Release of Nitrate, An Important Precursor for Reactive Nitrogen Species. American Association of Physicists in Medicine.
72. Schüler E, Chuang C, Yang Y, Xing L, Zhao W. Mitigating the uncertainty in small field dosimetry for stereotactic body radiation therapy by leveraging machine learning strategies. American Association for Radiation Oncology.
73. Vasudevan V, Huang C, Simiele E, Yu L, Xing L, Schüler E. Combining Monte Carlo with Deep Learning: Predicting high-resolution, low-noise dose distributions using a Generative Adversarial Network for fast and precise Monte Carlo Simulations. American Association for Radiation Oncology.
74. Ross J B, Merriott D J, Alhumaid S, Schüler E, Ko R, Bush K, Maxim P G, Gensheimer M F, Loo Jr B W, Diehn M. Pre-Treatment Lung FGD-PET Uptake is Correlated with Radiologic Lung Fibrosis after Stereotactic Ablative Radiotherapy (SABR). American Association for Radiation Oncology.
75. Schüler E, Kim AS, Melemenidis S, Gustavsson AK, Abid D, Wu Y, Liu F, Hristov D. Nanoparticle-mediated radiation-triggered release of nitrate, precursor of reactive nitrogen species, improves local tumor control. American Association for Radiation Oncology.
76. Andersson C, Shubbar E, Paris T, Langen B, Larson M, Schüler E, Olsson BM, Strand SE, Åkerström B, Gram M, Helou K, Forssell-Aronsson E. Early response in expression of radiation related proteins in mouse kidney after injection of 177Lu-octreotate with or without recombinant α1-microglobulin. The Swedish Cancer Foundation’s Annual meeting – Oncological Nuclear Radiation Therapy.
77. Thrower S, Holmes S, Prajapati S, Schüler E, Beddar S. Output Constancy of the W2 Scintillator in Flattening Filter Free Fields in a Medical Linac. American Association for Physicists in Medicine.
78. Johnson D, Titt U, Yang M, Wang X, Fujimoto T, Fredette N, Lin S, Zhu X, Iga K, Sahoo N, Koong A, Zhang X, Mohan R, Taniguchi C, Schüler E. Feasibility of a synchrotron-based proton FLASH irradiation platform for preclinical studies. Radiation Research Society.
79. No HJ, Wu YF, Skinner R, Lau B, Melemenidis S, Yu SJ, Surucu M, Schüler E, Bush K, Graves EE, PGMaxim, BWLoo. Feasibility of Clinically Practical Ultra-High Dose Rate (FLASH) Radiation Delivery by a Reversible Configuration of a Standard Clinical-Use Linear Accelerator. American Association for Radiation Oncology.
80. Wu YF, No HJ, Manjappa R, Skinner L, Yu SJ, Lau B, Surucu M, Schüler E, Bush K, Graves EE, Maxim PG, Loo BW. Validation of a Novel Cone-Less Set-up for Electron FLASH Radiation Delivery on a Clinical-Use Linear Accelerator. American Association for Radiation Oncology.
81. Schüler E, Fredette N, Chopra N, Darne C, Beddar S. Commissioning of the FLASH Mobetron system at MD Anderson Cancer Center. FRPT.
82. Bronk JK, Bronk LF, Singh S, Guan F, Wang X, Zhu R, Schüler E, Jiang D, Mohan R, Koong AC, Lang F, Grosshans DR. Radio-protective effects of ultra-high dose rate proton radiation (FLASH-RT) in a human induced pluripotent stem cell-derived cerebral organoid model. American Radium Society.
83. Liu K, Chopra N, Beddar S, Schüler E. Characterization of Orthochromic Film Dosimeter for Radiotherapy. South-West Chapter of the American Association for Physicists in Medicine (SWAAPM).
84. Liu K, Jorge PG, Moeckli R, Schüler E. Comprehensive Evaluation in the use of Gafchromic EBT3 film in high-dose radiation therapy. South-West Chapter of the American Association for Physicists in Medicine (SWAAPM).
85. Palmiero A, Glick A, Liu K, Chopra N, Beddar S, Schüler E. Commissioning of the FLASH Mobetron system at MDACC. South-West Chapter of the American Association for Physicists in Medicine (SWAAPM).
86. Palmiero A, Glick A, Liu K, Chopra N, Neill D, Massia S, Beddar S, Schüler E. Stability of the FLASH Mobetron system: an early MDACC Experience. South-West Chapter of the American Association for Physicists in Medicine (SWAAPM).
87. Liu K, Glick A, Palmiero A, Chopra N, Beddar S, Schüler E. Toroidal Detectors for Output and Energy Monitoring of Pulsed FLASH Irradiations. South-West Chapter of the American Association for Physicists in Medicine (SWAAPM).
88. Palmiero A, Glick A, Liu K, Chopra N, Neill D, Massia S, Schüler E, Beddar S. Stability of the FLASH Mobetron System. American Association for Physicists in Medicine (AAPM).
89. Liu K, Jorge P, Moeckli R, Schüler E. Comprehensive Evaluation in the Use of Gafchromic EBT3 Film for High-Dose Radiation Therapy. American Association for Physicists in Medicine (AAPM).
90. Chopra N, Liu K, Beddar S, Schüler E. Novel Radiochromic Film Dosimeter for Radiotherapy Applications. American Association for Physicists in Medicine (AAPM).
91. Schüler E, Palmiero A, Glick A, Liu K, Chopra N, Neill D, Massia S, Beddar S. Commissioning of the FLASH Mobetron System. American Association for Physicists in Medicine (AAPM).
92. Liu K, Glick A, Palmiero A, Chopra N, Beddar S, Schüler E. Utilization of Toroids for Output and Energy Monitoring of Pulsed Electron FLASH Beams. American Association for Physicists in Medicine (AAPM).
93. Bronk J, Bronk L, Singh S, Guan F, Wang X, Zhu X, Schüler E, Jiang D, Mohan R, Koong A, Lang F, Grosshans D. Enhanced radiation-sparing effects of ultra-high dose rate proton radiation (FLASH-RT) in a human induced pluripotent stem cell-derived cerebral organoid. ASTRO Annual Meeting.
94. Neill D, Delacerda J, Delahousaye A, Liu K, Pagel M, Taniguchi C, Schüler E. Imaging the in vivo oxygen levels to predict normal tissue sparing response following ultra-high dose rate FLASH irradiation. Radiation Research Society (RRS) Annual Meetin.
95. No H, Wu Y, Dworkin M, Ashraf MR, Manjappa R, Skinner L, Lau B, Melemenidis S, Viswanathan V, Yu A, Surucu M, Schüler E, Graves E, Maxim P, Loo B. Clinical LINAC-based electron FLASH: Pathway for practical translation to trials of FLASH radiotherapy. ASTRO Annual Meeting.
96. Ashraf MR, Melemenidis S, Skinner L, Manjappa R, Viswanathan V, Dutt S, Soto L, Yu A, Lau B, Surucu M, Graves T, Maxim P, Schüler E, Loo B. Development of a 3D-Printed Mouse Phantom for a Multi-Institutional Dosimetric Comparison Between FLASH and CONV irradiation. Radiation Research Society (RRS) Annual Meeting.
97. Wu Y, No H, Dworkin M, Manjappa R, Ashraf MR, Skinner L, Lau B, Melemenidis S, Viswanathan V, Yu A, Surucu M, Schüler E, Graves E, Maxim P, Loo B. Assessing Clinical Feasibility of a LINAC-based Electron FLASH Radiotherapy System Using an Anthropomorphic Phantom Under Realistic Clinical Conditions. ASTRO Annual Meeting.
98. Delahoussaye AM, Neill D, Liu K, Zang J, Taniguchi CM, Schüler E. Comparative normal tissue sparing between proton and electron beam after FLASH irradiation. Radiation Research Society (RRS) Annual Meeting.
99. Liu K, Neill D, Delahoussaye AM, Taniguchi C, Schüler E. Exploring the optimization potential of the FLASH effect through beam parameter manipulation. Radiation Research Society (RRS) Annual Meeting.
100. Baikalov A, Schüler E, Abolfath R, Mohan R, Wilkens J, Bartzsch S. Investigation of the FLASH Effect Mechanism with Radiochemical Assays. Radiation Research Society (RRS) Annual Meeting.
101. Liu K, Holmes S, Beddar S, Schüler E. Characterization of commercially available ionization chambers in FLASH Radiation therapy. FLASH Radiotherapy and Particle Therapy (FRPT) annual conference.
102. Connell L, Surry E, Beddar S, Young R, Schüler E. A methodology on determining FLASH radiation shielding requirements. FLASH Radiotherapy and Particle Therapy (FRPT) annual conference.
103. Wu Y, No H, Dworkin M, Manjappa R, Ashraf MR, Skinner L, Lau B, Melemenidis S, Viswanathan V, Yu A, Surucu M, Schüler E, Graves E, Maxim P, Loo B. Assessing Clinical Feasibility of a Cone-less Set-up for Electron FLASH Radiotherapy on a Clinical-use Linear Accelerator. FLASH Radiotherapy and Particle Therapy (FRPT) annual conference.
104. Liu K, Palmiero A, Chopra N, Beddar S, Schüler E. Dual beam current transformer design for real-time dose monitoring of electron FLASH beam parameters. FLASH Radiotherapy and Particle Therapy (FRPT) annual conference.
105. Palmiero A, Liu K, Chopra N, Connell L, Velasquez B, Neill D, Beddar S, Schüler E. Commissioning of the FLASH Mobetron System: an MDACC experience. FLASH Radiotherapy and Particle Therapy (FRPT) annual conference.
106. Baikalov A, Schüler E, Abolfath R, Mohan R, Wilkens J, Bartzsch S. Experimental validation of an analytical model of interspur interactions as a radiochemical mechanism of the FLASH effect. FLASH Radiotherapy and Particle Therapy (FRPT) annual conference.
107. Liu K, Holmes S, Schüler E, Beddar S. Characterization of the Exradin W2 in FLASH Radiation therapy. FLASH Radiotherapy and Particle Therapy (FRPT) annual conference.
108. Taniguchi CM, Neill D, Delahousaye A, Liu K, Schüler E. Comparative normal tissue sparing between proton and electron beam after FLASH irradiation. FLASH Radiotherapy and Particle Therapy (FRPT) annual conference.
109. Kumari N, Neill D, Delacerda J, Delahousaye A, Liu K, Pagel M, Taniguchi CM, Schüler E. Studying the role of in vivo oxygen levels to predict normal tissue sparing following ultra-high dose rate FLASH irradiation. FLASH Radiotherapy and Particle Therapy (FRPT) annual conference.
110. Palmiero A, Schüler E, Connell L, Velasquez B, Liu K, Chopra N, Neill D, Beddar S. Short- and long-term Stability of the Mobetron FLASH System. FLASH Radiotherapy and Particle Therapy (FRPT) annual conference.
111. Abolfath R, Baikalov A, Afshordi N, Schüler E, Mohan R, Bartzsch S. The effect of non-ionizing excitations on the diffusion of ion species and inter-track correlations at FLASH ultra-high dose rate radiotherapy. FLASH Radiotherapy and Particle Therapy (FRPT) annual conference.
112. Chopra N, Liu K, Beddar S, Schüler E. Characterization of a novel Orthochromic Film for FLASH. FLASH Radiotherapy and Particle Therapy (FRPT) annual conference.
113. Velasquez B, Liu K, Chopra N, Beddar S, Schüler E. Characterization of Luminescent Based Dosimeters for Ultra-High Dose Rate (FLASH) electron beams. FLASH Radiotherapy and Particle Therapy (FRPT) annual conference.
114. Liu K, Palmiero A, Chopra N, Beddar S, Schüler E. Electron Ultra-High Dose-Rate (FLASH) beam monitoring and control through beam current transformers. ESTRO.
115. Liu K, Holmes S, Schüler E, Beddar S. Characterization of the Exradin W2 in FLASH Radiation Therapy. ESTRO.
116. Palmiero AN, Abana CO, Liu K, Green MM, Li Z, Harris L, Mayor S, Samuel KQ, Younkin RA, Moore EJ, Norton W, Swain J, Fowlkes N, Koong A, Woodward WA, Taniguchi C, Beddar S, Mitra D, Lin SH, Schüler E. Single- Fraction Electron FLASH: Subacute Cutaneous Toxicity Analysis via Swine Models. AAPM annual meeting.
117. Bronk LF, Singh S, Bronk J, Liu K, Guan F, Mohan R, Koong AC, Lang F, Schüler E, Grosshans D. The Effects of Flash Radiation in an Advanced Model of Normal Human Brain Tissue. AAPM annual meeting.
118. Ashraf MR, Melemenidis S, Liu K, Velasquez BD, Skinner L, Yu AS, Surucu M, Graves EE, Maxim PG, Schüler E, Loo BW. Multi-Institutional Verification and End-to-End Testing of Flash and Conventional Dose Distributions Under Varying Setup Conditions Using a 3D Printed Mouse Phantom. AAPM annual meeting.
119. Liu K, Holmes S, Schüler E, Beddar S. Feasibility of using Exradin W2 in its current configuration for FLASH Beamlines. AAPM annual meeting.
120. Lopez-Hernandez A, Baikalov A, Liu K, Schüler E. Characterization of a novel solid core Faraday Collector in electron FLASH beamlines. AAPM annual meeting.
121. Palmiero AN, Abana CO, Velasquez B, Liu K, Beddar S, Mitra D, Lin SH, Schüler E. Clinical Workflow Implementation of Electron FLASH Radiation Therapy via Swine Models. AAPM annual meeting.
122. Liu K, Holmes S, Schüler E, Beddar S. How ion chamber design influences their response in ultra-high dose-rate beamlines. AAPM annual meeting.
123. West NA, Connell L, Liu K, Baikalov A, Velasquez B, Wang E, Mims N, Aguilar E, Neill D, Delahoussaye A, Mitra D, Schüler E. Hypo-fractionated ultra-high dose rate (FLASH) radiation therapy reduces skin toxicity and leg contracture in mouse model. AAPM annual meeting.
124. Liu K, Velasquez B, Schüler E. The dose-rate independence and usability of Al2O3:C OSLDs and LiF:Mg,Ti TLDs in FLASH Beamlines. AAPM annual meeting.
125. Connell L, Young R, Schüler E. Pulse-by-Pulse Beam Symmetry Monitoring in a Ultra-High Dose Rate (FLASH) Linear Accelerator through the Internal Ion Chamber. AAPM annual meeting.
126. Insley B, Bartkoski D, Fru LC, Tailor R, Schüler E, Kry S, Salehpour M. Monte Carlo Energy and Volume Correction Factor Calculation for Plane-Parallel Ion Chamber in a Convergent Monoenergetic Photon Beam. AAPM annual meeting.
127. Lim R, Connell L, Coupey N, Nguyen C, Schüler E. Pulse-by-pulse control system for accurate dose and dose per pulse delivery on ultra-high dose rate (FLASH) - capable Linear Accelerators. AAPM annual meeting.
128. Liu K, Velasquez B, Schüler E. Investigation in the signal regeneration of high-dose OSLDs annealed under various conditions. AAPM annual meeting.
129. Liu K, Green MM, Mims NP, Aguilar EA, Delahoussaye AM, Neill DW, Fowlkes NW, Taniguchi CM, Schüler E. Examining the acute and long-term response of normal tissue irradiated in FLASH and CONV RT. International Congress for Radiation Research (ICRR).
130. Abana CO, Palmiero AN, Velasquez B, Liu K, Beddar S, Mitra D, Schüler E, Lin SH. Feasibility and Clinical Implementation of Electron FLASH Radiation Therapy in the Yorkshire Swine Model. ASTRO.
131. Ashraf MR, Melemenidis S, Liu K, Velasquez BD, Skinner L, Yu AS, Surucu M, Graves EE, Maxim PG, Schüler E, Loo BW. Anatomically realistic 3D Printed Mouse Phantom for Multi-Institutional Benchmarking of FLASH and CONV Irradiation. ASTRO.
132. Abana CO, Palmiero AN, Liu K, Green MM, Li Z, Harris L, Mayor S, Samuel KQ, Younkin RA, Moore EJ, Norton W, Swain J, Fowlkes N, Koong A, Woodward WA, Taniguchi C, Beddar S, Mitra D, Schüler E, Lin SH. Subcutaneous Toxicity with Single-Fraction Electron FLASH RT in Yorkshire Swine. ASTRO.
133. Perles LA, Niedzielski JS, Sawakuchi GO, Paulpeter RM, Schüler E, Taniguchi CM, Ludmir E, Das P, Koong AC, Koay E, Beddar S. Assessment of the stability of the spatial bio-distribution of NBTXR3 injections for Locally Advanced or Borderline-Resectable Pancreatic Ductal Adenocarcinoma patients undergoing Radiation Therapy treatment. ASTRO.
134. Chang E, Wong FC, Erwin WD, Das P, Holliday EB, Koong AC, Ludmir EB, Minsky BD, Noticewala SS, Smith GL, Taniguchi CM, Beddar S, Martin Paulpeter RM, Niedzielski JS, Perles LA, Sawakuchi GO, Schüler E, Park P, Kaseb AO, Lee SS, Tzeng CD, Vauthey J, Koay E. Phase 1 Trial of Liver-Directed Ablative Radiotherapy for Patients with Low Functional Liver Volume. ASTRO.
135. Palmiero AN, Abana CO, Liu K, Green MM, Li Z, Harris L, Younkin RA, Mayor S, Samuel KQ, R Garrow KK, Moore EJ, Fowlkes N, Swain J, Norton W, Koong AC, Woodward WA, Taniguchi C, Beddar S, Mitra D, Schüler E, Lin SH. Clinical workflow implementation of electron FLASH radiation therapy via swine models. FLASH Radiotherapy and Particle Therapy (FRPT).
136. Saenz FR, Velazquez B, Schüler E, T Spiotto AM. Rescue of radiation induced lymphocyte depletion by FLASH radiotherapy. FLASH Radiotherapy and Particle Therapy (FRPT).
137. Liu K, Green MM, Mims NP, Aguilar EA, Delahoussaye AM, Neill D, Fowlkes NW, Taniguchi CM, Schüler E. Investigating Acute and Long-Term Gastrointestinal and Hematological Toxicity in electron FLASH and CONV RT: A Comparative Analysis. FLASH Radiotherapy and Particle Therapy (FRPT).
138. Abana CO, Palmiero AN, Liu K, Green MM, Li Z, Harris L, Younkin RA, Mayor S, Samuel KQ, R Garrow KK, Moore EJ, Fowlkes N, Swain J, Norton W, Koong AC, Woodward WA, Taniguchi C, Beddar S, Mitra D, Schüler E, Lin SH. Cutaneous Tissue Microenvironment Effects After Single- and fractionated Dose Electron FLASH-RT in Yorkshire Swine. FLASH Radiotherapy and Particle Therapy (FRPT).
139. Soda T, Connell L, Liu K, Velasquez B, Wang E, Mims N, Aguilar E, Neill D, Delahoussaye A, Baikalov A, Schüler E, Mitra D. Hypofractionated FLASH radiation therapy reduces skin and soft tissue toxicity in a murine model. FLASH Radiotherapy and Particle Therapy (FRPT).
140. Tao R, Liu K, Neill D, Velasquez B, Mims N, Schüler E, Lin SH. Thoracic FLASH radiotherapy reduces damage to normal lungs and hearts and significantly spares peripheral blood lymphocytes through reduction of lymphocyte apoptosis. FLASH Radiotherapy and Particle Therapy (FRPT).
141. Baikalov A, Lopez-Hernandez A, Liu K, Bartzsch S, Schüler E. Characterization of a novel, highly time-resolved detector at ultra-high dose rates. FLASH Radiotherapy and Particle Therapy (FRPT).
142. Tao R, Liu K, Neill D, Velasquez B, Mims N, Schüler E, Lin SH. Thoracic FLASH radiotherapy reduce damage to normal lungs and heart and significantly spares peripheral blood lymphocytes through reduction of lymphocyte apoptosis. FLASH Radiotherapy and Particle Therapy (FRPT).
143. Xu Q, Toesca D, Schüler E, Jamalian A, Alkim E, Chang DT, Fisher Jr GA, Vitzthum L, Gevaert O, Itakura H. Predicting rapid progression and overall survival in stage II-III pancreatic cancer using a CT-based radiomic signature. ASCO Gastrointestinal Cancers Symposium.
144. Xu Q, Alkim E, Chang D, Fisher G, Jamalian A, Schüler E, Toesca D, Vitzthum L, Gevaert O, Itakura H. Predicting Rapid Progression and Overall Survival in Stage II-III Pancreatic Cancer Using a CT-based Radiomic Signature. 2024 ASCO Gastrointestinal Cancers Symposium.
145. Liu K, Titt U, Esplen N, Connell L, Konradsson E, Yang M, Wang X, Takaoka T, Li Z, Koong AC, Mitra D, Mohan R, Loo BW, MD, Lin SH, Schüler E. Discordance in acute gastrointestinal toxicity between synchrotron-based proton and linac-based electron ultra-high dose rate irradiation. ESTRO.
146. Liu K, Kahn A, Holmes S, Dewerd L, Beddar S, Schüler E. Development of next-generation ion chambers for reference dosimetry in FLASH. ESTRO.
147. Scott H, Taylor P, Alvarez P, Schüler E, Kry S. The status of the Imaging and Radiation Oncology Core’s –credentialling program for FLASH radiotherapy. Council on Ionizing Radiation Measurements & Standards (CIRMS) Annual Meeting.
148. Itakura H, Xu Q, Toesca D, Vitzthum L, Jamalian A, Schüler E, Alkim E, Baclay J, Chang DT, Fisher Jr GA. Clinical determinants of survival in patients with stage II-III pancreatic cancer. American Society of Clinical Oncology.
149. Liu K, Waldrop T, Aguilar E, Mims NP, Neill D, Delahoussaye AM, Taniguchi C, Mitra D, Schüler E. The FLASH Effect is dependent on Dose per Pulse and not Mean Dose Rate for Gastrointestinal Irradiations. ESTRO.
150. Hu Z, Meyer H, Schüler E, Mohan R, Titt U. Conformal Proton FLASH Radiotherapy for Pediatric Osteosarcoma with a Mini-SOBP Scanning Strategy. AAPM annual meeting.
151. Liu K, Holmes S, Khan AU, Hooten B, Dewerd L, Schüler E, Beddar S. Development of novel parallel plate ion chambers for reference dosimetry applications in electron FLASH Radiotherapy. AAPM annual meeting.
152. Kim Y, Meyer H, Lopez A, Baikalov A, Schüler E, Mohan R. An investigation of the proton dose rate effect under various cellular conditions and beam parameters using Monte Carlo simulations. AAPM annual meeting.
153. Meyer H, Wang L, Jiang D, Titt U, Schüler E, Mohan R. Design of Parallel Opposed Ramp Fields for in-Vivo Uniform Proton LET Experiments. AAPM annual meeting.
154. Melemenidis S, Ashraf MR, Chen D, Liu K, Velasquez BD, Connell L, Katila N, Dutt S, Schüler E, Loo BW. Multi-Institutional Dosimetry Protocol for Standardize Dosimetry across Two Research Facilities for Preclinical Radiobiological Experiments. AAPM annual meeting.
155. Caggiano EG, Valasquez B, Taniguchi CM, Schüler AE. FLASH compared to conventional radiation therapy differentially impacts mitochondrial DNA damage in pancreatic cancer. Radiation Research Society Annual Meeting.
156. Liu K, Waldrop T, Aguilar E, Mims NP, Neill D, Delahoussaye AM, Taniguchi C, Mitra D, Schüler E. The impact of dose per pulse and mean dose rate on the magnitude of radiation induced gastrointestinal toxicity under FLASH conditions. Radiation Research Society Annual Meeting.
157. Liu K, Titt U, Yang M, Zhu R, Wang X, Hu Z, Aguilar E, Mims N, Neill D, Esplen N, Konradsson E, Connell L, Iga K, Takaoka T, Koong A, Lin S, Mohan R, Schüler E. Synchrotron-based Proton FLASH irradiation induces greater acute gastrointestinal toxicity compared to conventional dose rate proton and electron FLASH irradiation. Radiation Research Society Annual Meeting.
158. Waldrop T, Murley G, Velasquez B, Neill D, Delahoussaye A, Schuler W, La Cerda JD, Pagel M, Schüler E. Local oxygen tension is a key player in the FLASH effect. Radiation Research Society Annual Meeting.
159. Liu K, Holmes S, Kahn A, Hooten B, Dewerd L, Schüler E, Beddar S. Development of next-generation ion chambers for reference dosimetry in FLASH. Radiation Research Society Annual Meeting.
160. Lopez A, Baikalov A, Esplen N, Bartzsch S, Schüler E. Experimental Platform to Characterize the Radiation Chemistry of FLASH-RT. adiation Research Society Annual Meeting.
161. Baikalov A, Wang E, Bartzsch S, Schüler E. Automated Workflow for Histological Structure Enumeration, a Proof-of-Principle study in Colonic Crypt Counting. Radiation Research Society Annual Meeting.
162. Caggiano EG, Valasquez B, Taniguchi CM, Schüler E. FLASH compared to conventional dose rate irradiation differentially impacts mitochondrial DNA damage in pancreatic cancer. FLASH Radiotherapy and Particle Therapy (FRPT).
163. Liu K, Waldrop T, Aguilar E, Mims NP, Neill D, Delahoussaye AM, Taniguchi C, Mitra D, Schüler E. Redefining the conditions for inducing the FLASH Effect: the impact of dose per pulse and mean dose rate on tissue sparing in the gastrointestinal tract. FLASH Radiotherapy and Particle Therapy (FRPT).
164. Tao R, Liu K, Neill D, Aguilar E, Velasquez B, Mims N, Schüler E, Lin SH. Single and fractionated thoracic FLASH radiotherapy significantly spare peripheral blood lymphocytes and reduce radiation induced lymphocyte apoptosis and immunosuppression. FLASH Radiotherapy and Particle Therapy (FRPT).
165. Melemenidis S, Ashraf MR, Chen D, Liu K, Velasquez BD, Connell L, Katila N, Dutt S, Schüler E, Loo BW. An inter-institutional comparative study of the FLASH effect on the gastrointestinal tract. FLASH Radiotherapy and Particle Therapy (FRPT).
166. Bronk JK, Bronk LF, Singh S, Liu K, Lang FF, Schüler E, Grosshans DR. Neurotoxicity mitigation after FLASH radiation in an advanced normal tissue model of human brain tissue: oxygen dependence, functional preservation, and transcriptomic profiling. FLASH Radiotherapy and Particle Therapy (FRPT).
167. Waldrop T, Murley G, Velasquez B, Neill D, Delahoussaye A, Schuler W, La Cerda JD, Pagel M, Schüler E. Tissue oxygenation alters the FLASH effect. FLASH Radiotherapy and Particle Therapy (FRPT) annual conference.
168. Tho D, Liu K, Holmes S, Schüler E, Beddar S. Plastic scintillator radiation study under ultra high dose rate FLASH electron beams. FLASH Radiotherapy and Particle Therapy (FRPT).
169. Liu K, Holmes S, Kahn A, Hooten B, Dewerd L, Schüler E, Beddar S. Development and design performance of next generation parallel plate ion chambers for FLASH dosimetry. FLASH Radiotherapy and Particle Therapy (FRPT).
170. Tao R, Liu K, Neill D, Aguilar E, Velasquez B, Mims N, Schüler E, Lin SH. Thoracic FLASH RT improves recovery of radiation induced lymphopenia and systemically promotes proliferation of bone marrow stem/progenitor cells. FLASH Radiotherapy and Particle Therapy (FRPT).
171. Liu K, Titt U, Yang M, Zhu R, Wang X, Hu Z, Aguilar E, Mims N, Neill D, Esplen N, Konradsson E, Connell L, Iga K, Takaoka T, Koong A, Lin S, Mohan R, Schüler E. Synchrotron-based Proton FLASH irradiation induces greater acute gastrointestinal toxicity compared to conventional dose rate proton and electron FLASH irradiation. FLASH Radiotherapy and Particle Therapy (FRPT).
172. Saenz F, Velasquez B, Delahoussaye A, Connell L, Mims N, Neill D, Schüler E, Spiotto M. FLASH radiotherapy enhances immune activation and spares lymphocytes in tumor draining lymph nodes. AACR Special Conference in Cancer Research: Translating Targeted Therapies in Combination with Radiotherapy.
173. Gatica-Gutierrez H, Joshi P, Gagliano G, Vargas-Hernandez S, Raterink A, Velazquez B, Schüler E, Gustavsson A. Understanding the molecular mechanism of the FLASH effect in radiation therapy using super-resolution microscopy. BPS annual conference.
174. Konradsson E, Whitmore L, Esplen N, Baig S, Connell L, Aguilar E, Neill D, Mitra D, Schüler E. Single-pulse FLASH radiotherapy reduces acute skin and soft tissue toxicity compared to conventional radiotherapy in a mouse hindlimb model. ESTRO.
175. Konradsson E, Liu K, Baig S, Lopez AH, Velasquez B, Mayor S, Samuel K, Viscarra T, Garrow K, Moore EJ, Norton W, Swain J, Koong AC, Lin SH, Schüler E, Mitra D. Safety and cutaneous toxicity of hypofractionated FLASH and conventional radiotherapy in a clinically relevant swine skin model. ESTRO.

Book Chapters

1. Maxim, PG, Schüler, E, Petersson, K. Ultra-high dose-rate electron FLASH therapy. In: Spatially Fractionated, Microbeam and Flash Radiation Therapy: Physics and multidisciplinary approach. IOP Publishing, 22.1-22.13, 2023.