Evelyne M. Loyer, M.D.
Department of Abdominal Imaging, Division of Diagnostic Imaging - Clinical
About Dr. Evelyne M. Loyer
Dr. Evelyne Loyer is a Clinical Professor of Radiology and a board-certified radiologist in the Department of Abdominal Imaging at MD Anderson Cancer Center. Dr. Loyer has served as a radiologist with MD Anderson Cancer Center since 1990.
Dr. Loyer's clinical research focuses on the imaging of hepatobiliary malignancies particularly, preoperative staging and assessment of the response to chemotherapy. Dr. Loyer developed non size based criteria of response to bevacizumab, which correlate with the pathologic response in patients with metastatic colorectal carcinoma. Radiographic observations have also lead to the development of the new pathologic indicator of response in the same patient's population.
Present Title & Affiliation
Primary Appointment
Clinical Professor, Department of Abdominal Imaging, Division of Diagnostic Imaging, The University of Texas MD Anderson Cancer Center, Houston, TX
Research Interests
Colorectal Liver Metastases
Clinical Interests
CT
PET/CT
Hepato-biliary Cancer
Education & Training
Degree-Granting Education
1978 | Medical School Paris V, Paris, FRA, MD, Medicine |
1971 | Lycee D'Etat Mixte De Chantilly, Paris, FRA, BS, General Studies |
Postgraduate Training
1987-1990 | Clinical Fellowship, Cross Sectional Imaging, The University of Texas MD Anderson Cancer Center, Houston, TX |
1985-1987 | Clinical Fellowship, Pediatric Radiology, Children's Hospital National Medical Center, Washington, DC |
1981-1985 | Clinical Residency, Radiology, Universite Paris Descartes Medical School Paris V, Paris |
1980-1981 | Clinical Internship, Diagnostic Radiology, Nominated Internat Des Hospitaux Prives de Paris, Paris |
Board Certifications
1992 | American Board of Radiology |
Experience & Service
Academic Appointments
Professor, Department of Diagnostic Radiology, Division of Diagnostic Imaging, The University of Texas MD Anderson Cancer Center, Houston, TX, 2006 - 2019
Selected Publications
Peer-Reviewed Articles
- Mazard T, Mollevi C, Loyer EM, Léger J, Chautard R, Bouché O, Borg C, Armand-Dujardin P, Bleuzen A, Assenat E, Lecomte T. Prognostic value of the tumor-to-liver density ratio in patients with metastatic colorectal cancer treated with bevacizumab-based chemotherapy. A post-hoc study of the STIC-AVASTIN trial. Cancer Imaging 24(1):77, 2024. e-Pub 2024. PMID: 38886836.
- Ren L, Zhu D, Benson AB, Nordlinger B, Koehne CH, Delaney CP, Kerr D, Lenz HJ, Fan J, Wang J, Gu J, Li J, Shen L, Tsarkov P, Tejpar S, Zheng S, Zhang S, Gruenberger T, Qin X, Wang X, Zhang Z, Poston GJ, Xu J, SINCE (Shanghai International Consensus Expert Group on Colorectal Liver Metastases) Group. Shanghai international consensus on diagnosis and comprehensive treatment of colorectal liver metastases (version 2019). Eur J Surg Oncol 46(6):955-966, 2020. e-Pub 2020. PMID: 32147426.
- Popnoe DO, Ng CS, Zhou S, Kaur H, Kang HC, Loyer EM, Kappadath SC, Jones AK. Comparison of virtual to true unenhanced abdominal computed tomography images acquired using rapid kV-switching dual energy imaging. PLoS One 15(9):e0238582, 2020. e-Pub 2020. PMID: 32966278.
- Yedururi S, Kang H, Cox VL, Chawla S, Le O, Loyer EM, Marcal L. Tumor thrombus in the venous drainage pathways of primary, recurrent and metastatic disease on routine oncologic imaging studies: beyond primary tumor in hepatocellular carcinoma and renal cell carcinoma. Br J Radiol 92(1098):20180478, 2019. e-Pub 2019. PMID: 30844299.
- Marcal LP, Patnana M, Yedururi S, Chuang HH, Devine CE, Cox V, Dasari A, Loyer E. Abdominal manifestations of neuroendocrine tumors. Digestive Disease Interventions. e-Pub 2019.
- Lee AJ, Loyer EM, Kang HC, Aloia TA, Tzeng CD, Vauthey JN, Chun YS. Intrahepatic recurrence patterns predict survival after resection of colorectal liver metastases. Ann Surg Oncol 26(1):275-281, 2019. e-Pub 2018. PMID: 30362064.
- Overman MJ, Ferrarotto R, Raghav K, George B, Qiao W, Machado KK, Saltz LB, Mazard T, Vauthey JN, Hoff PM, Hobbs B, Loyer EM, Kopetz S. The addition of Bevacizumab to Oxaliplatin-based chemotherapy: impact upon hepatic sinusoidal injury and thrombocytopenia. J Natl Cancer Inst 110(8):888-894, 2018. e-Pub 2018. PMID: 29346573.
- Mazard T, Boonsirikamchai P, Overman MJ, Asran MA, Choi H, Herron D, Eng C, Maru DM, Ychou M, Vauthey JN, Loyer EM, Kopetz S. Comparison of early radiological predictors of outcome in patients with colorectal cancer with unresectable hepatic metastases treated with Bevacizumab. Gut 67(6):1095-1102, 2018. e-Pub 2017. PMID: 29084828.
- Yedururi S, Terpenning S, Gupta S, Fox P, Martin SS, Conrad C, Loyer EM. Radiofrequency ablation of hepatic tumor: subjective assessment of the perilesional vascular network on contrast-enhanced computed tomography before and after ablation can reliably predict the risk of local recurrence. J Comput Assist Tomogr 41(4):607-613, 2017. PMID: 28722702.
- Yamashita S, Loyer E, Kang HC, Aloia TA, Chun YS, Mehran RJ, Eng C, Lee JE, Vauthey JN, Conrad C. Total transthoracic approach facilitates laparoscopic hepatic resection in patients with significant prior abdominal surgery. Ann Surg Oncol 24(5):1376-1377, 2017. e-Pub 2016. PMID: 27878479.
- Bache ST, Stauduhar PJ, Liu X, Loyer EM, John RX. Quantitation of clinical feedback on image quality differences between two CT scanner models. J Appl Clin Med Phys 18(2):163-169, 2017. e-Pub 2017. PMID: 28300384.
- Yamashita S, Loyer EM, Chun YS, Javle M, Lee JE, Vauthey JN, Conrad C. Laparoscopic management of gallbladder cancer: a stepwise approach. Ann Surg Oncol 23(Suppl 5):892-893, 2016. e-Pub 2016. PMID: 27456958.
- Frentzas S, Simoneau E, Bridgeman VL, Vermeulen PB, Foo S, Kostaras E, Nathan MR, Wotherspoon A, Gao ZH, Shi Y, Van den Eynden G, Daley F, Peckitt C, Tan X, Salman A, Lazaris A, Gazinska P, Berg TJ, Eltahir Z, Ritsma L, van Rheenen J, Khashper A, Brown G, Nyström H, Sund M, Van Laere S, Loyer EM, Dirix L, Cunningham D, Metrakos P, Reynolds AR. Vessel co-option mediates resistance to anti-angiogenic therapy in liver metastases. Nat Med 22(11):1294-1302, 2016. e-Pub 2016. PMID: 27748747.
- Ismael HN, Loyer EM, Kaur H, Conrad C, Vauthey JN, Aloia T. Evaluating the clinical applicability of the European staging system for perihilar cholangiocarcinoma. J Gastrointest Surg 20(4):741-747, 2016. e-Pub 2016. PMID: 26801328.
- Adam R, de Gramont A, Figueras J, Kokudo N, Kunstlinger F, Loyer EM, Poston G, Rougier P, Rubbia-Brandt L, Sobrero A, Teh C, Tejpar S, Van Cutsem E, Vauthey JN, Påhlman L, of the EGOSLIM (Expert Group on OncoSurgery management of Liver Metastases) group. Managing synchronous liver metastases from colorectal cancer: a multidisciplinary international consensus. Cancer Treat Rev 41(9):729-741, 2015. e-Pub 2015. PMID: 26417845.
- Peungjesada S, Aloia TA, Fox P, Chasen B, Shin S, Baiomy A, Loyer EM. (18)F-FDG uptake at the surgical margin after hepatic resection: patterns of uptake and differential diagnosis. Eur Radiol 25(8):2453-2459, 2015. e-Pub 2015. PMID: 25678079.
- Mise Y, Zimmitti G, Shindoh J, Kopetz S, Loyer EM, Andreou A, Cooper AB, Kaur H, Aloia TA, Maru DM, Vauthey JN. RAS mutations predict radiologic and pathologic response in patients treated with chemotherapy before resection of colorectal liver metastases. Ann Surg Oncol 22(3):834-842, 2015. e-Pub 2014. PMID: 25227306.
- Zhou JH, Rosen D, Andreou A, Brouquet A, Abbott D, Loyer EM, Gonzalez-Angulo AM, Kopetz S, Meric-Bernstam F, Kuerer H, Abdalla E, Vauthey JN, Sahin AA, Maru DM. Residual tumor thickness at the tumor-normal tissue interface predicts the recurrence-free survival in patients with liver metastasis of breast cancer. Ann Diagn Pathol 18(5):266-270, 2014. e-Pub 2014. PMID: 25205085.
- Westin JR, McLaughlin P, Romaguera J, Hagemeister FB, Pro B, Dang NH, Samaniego F, Rodriguez MA, Fayad L, Oki Y, Fanale M, Fowler N, Nastoupil L, Feng L, Loyer EM, Younes A. Paclitaxel, Topotecan and Rituximab: long term outcomes of an effective salvage programme for relapsed or refractory aggressive B-cell non-Hodgkin lymphoma. Br J Haematol 167(2):177-184, 2014. e-Pub 2014. PMID: 25039868.
- Huang SY, Aloia TA, Shindoh J, Ensor J, Shaw CM, Loyer EM, Vauthey JN, Wallace MJ. Efficacy and safety of portal vein embolization for two-stage hepatectomy in patients with colorectal liver metastasis. J Vasc Interv Radiol 25(4):608-617, 2014. e-Pub 2013. PMID: 24315549.
- Hassan MM, Kaseb A, Etzel CJ, El-Serag H, Spitz MR, Chang P, Hale KS, Liu M, Rashid A, Shama M, Abbruzzese JL, Loyer EM, Kaur H, Hassabo HM, Vauthey JN, Wray CJ, Hassan BS, Patt YZ, Hawk E, Soliman KM, Li D. Genetic variation in the PNPLA3 gene and hepatocellular carcinoma in USA: risk and prognosis prediction. Mol Carcinog 52 Suppl 1:139-147, 2013. e-Pub 2013. PMID: 23776098.
- Peungjesada S, Aloia TA, Kaur H, Marcal L, Choi H, Vauthey JN, Loyer EM. Intrabiliary growth of colorectal liver metastasis: spectrum of imaging findings and implications for surgical management. AJR Am J Roentgenol 201(4):W582-W589, 2013. PMID: 24059396.
- Andreou A, Aloia TA, Brouquet A, Dickson PV, Zimmitti G, Maru DM, Kopetz S, Loyer EM, Curley SA, Abdalla EK, Vauthey JN. Margin status remains an important determinant of survival after surgical resection of colorectal liver metastases in the era of modern chemotherapy. Ann Surg 257(6):1079-1088, 2013. PMID: 23426338.
- Shindoh J, Chun YS, Loyer EM, Vauthey JN. Non-size-based response criteria to preoperative chemotherapy in patients with colorectal liver metastases: the morphologic response criteria. Curr Colorectal Cancer Rep 9(2):198-202, 2013. PMID: 23710157.
- Chun YS, House MG, Kaur H, Loyer EM, Paradis V, Vauthey JN. SSAT/AHPBA joint symposium on evaluation and treatment of benign liver lesions. J Gastrointest Surg 17(4):636-644, 2013. e-Pub 2013. PMID: 23377783.
- Peungjesada S, Chuang HH, Prasad SR, Choi H, Loyer EM, Bronstein Y. Evaluation of cancer treatment in the abdomen: trends and advances. World J Radiol 5(3):126-142, 2013. PMID: 23671749.
- Adams RB, Aloia TA, Loyer EM, Pawlik TM, Taouli B, Vauthey JN. Selection for hepatic resection of colorectal liver metastases: expert consensus statement. HPB (Oxford) 15(2):91-103, 2013. PMID: 23297719.
- Shindoh J, Loyer EM, Kopetz S, Boonsirikamchai P, Maru DM, Chun YS, Zimmitti G, Curley SA, Charnsangavej C, Aloia TA, Vauthey JN. Optimal morphologic response to preoperative chemotherapy: an alternate outcome end point before resection of hepatic colorectal metastases. J Clin Oncol 30(36):4566-4572, 2012. e-Pub 2012. PMID: 23150701.
- Adam R, De Gramont A, Figueras J, Guthrie A, Kokudo N, Kunstlinger F, Loyer EM, Poston G, Rougier P, Rubbia-Brandt L, Sobrero A, Tabernero J, Teh C, Van Cutsem E, Jean-Nicolas Vauthey of the EGOSLIM (Expert Group on OncoSurgery management of Liver Metastases) group. The OncoSurgery approach to managing liver metastases from colorectal cancer: a multidisciplinary international consensus. Oncologist 17(10):1225-1239, 2012. e-Pub 2012. PMID: 22962059.
- Asran MK, Loyer EM, Kaur H, Choi H. Case 177: congenital absence of the portal vein with hepatic adenomatosis. Radiology 262(1):364-367, 2012. PMID: 22190661.
- Boonsirikamchai P, Asran MA, Maru DM, Vauthey JN, Kaur H, Kopetz S, Loyer EM. CT findings of response and recurrence, independent of change in tumor size, in colorectal liver metastasis treated with Bevacizumab. AJR Am J Roentgenol 197(6):W1060-W1066, 2011. PMID: 22109320.
- Brouquet A, Overman MJ, Kopetz S, Maru DM, Loyer EM, Andreou A, Cooper A, Curley SA, Garrett CR, Abdalla EK, Vauthey JN. Is resection of colorectal liver metastases after a second-line chemotherapy regimen justified?. Cancer 117(19):4484-4492, 2011. e-Pub 2011. PMID: 21446046.
- Eckmann KR, Patel DK, Landgraf A, Slade JH, Lin E, Kaur H, Loyer E, Weatherly JM, Javle M. Chemotherapy outcomes for the treatment of unresectable intrahepatic and hilar cholangiocarcinoma: a retrospective analysis. Gastrointest Cancer Res 4(5-6):155-160, 2011. PMID: 22295126.
- Brouquet A, Vauthey JN, Badgwell BD, Loyer EM, Kaur H, Curley SA, Abdalla EK. Hepatectomy for recurrent colorectal liver metastases after radiofrequency ablation. Br J Surg 98(7):1003-1009, 2011. PMID: 21541936.
- Boonsirikamchai P, Loyer EM, Choi H, Charnsangavej C. Planning and follow-up after ablation of hepatic tumors: imaging evaluation. Surg Oncol Clin N Am 20(2):301-315, 2011. PMID: 21377585.
- Brouquet A, Abdalla EK, Kopetz S, Garrett CR, Overman MJ, Eng C, Andreou A, Loyer EM, Madoff DC, Curley SA, Vauthey JN. High survival rate after two-stage resection of advanced colorectal liver metastases: response-based selection and complete resection define outcome. J Clin Oncol 29(8):1083-1090, 2011. e-Pub 2011. PMID: 21263087.
- Mohamed AA, Kaur H, Loyer EM, Choi H. Diagnosis please: part 1. Radiology 260(3):908-910, 2011.
- Maru DM, Kopetz S, Boonsirikamchai P, Agarwal A, Chun YS, Wang H, Abdalla EK, Kaur H, Charnsangavej C, Vauthey JN, Loyer EM. Tumor thickness at the tumor-normal interface: a novel pathologic indicator of chemotherapy response in hepatic colorectal metastases. Am J Surg Pathol 34(9):1287-1294, 2010. PMID: 20697255.
- Overman MJ, Maru DM, Charnsangavej C, Loyer EM, Wang H, Pathak P, Eng C, Hoff PM, Vauthey JN, Wolff RA, Kopetz S. Oxaliplatin-mediated increase in spleen size as a biomarker for the development of hepatic sinusoidal injury. J Clin Oncol 28(15):2549-2555, 2010. PMID: 20406923.
- Chun YS, Vauthey JN, Boonsirikamchai P, Maru DM, Kopetz S, Palavecino M, Curley SA, Abdalla EK, Kaur H, Charnsangavej C, Loyer EM. Association of computed tomography morphologic criteria with pathologic response and survival in patients treated with Bevacizumab for colorectal liver metastases. JAMA 302(21):2338-2344, 2009. PMID: 19952320.
- Wang M, Oki Y, Pro B, Romaguera JE, Rodriguez MA, Samaniego F, McLaughlin P, Hagemeister F, Neelapu S, Copeland A, Samuels BI, Loyer EM, Ji Y, Younes A. Phase II study of yttrium-90-Ibritumomab Tiuxetan in patients with relapsed or refractory mantle cell lymphoma. J Clin Oncol 27(31):5213-5218, 2009. PMID: 19770379.
- Lee SJ, Gounder M, Rubin EH, Li JM, Gu Z, Thalasila A, Loyer EM, Kudelka AP, Verschraegen CF. Optimal modeling for phase I design of a two drug combination-results of a phase I study of Cisplatin with 9-nitrocamptothecin. Invest New Drugs 26(6):541-551, 2008. e-Pub 2008. PMID: 18600301.
- Kaur H, Loyer EM, David CL, Sawaf H, DuBrow RA, Ibrahim NK. Radiologic findings in taxane induced colitis. Eur J Radiol 66(1):75-78, 2008. PMID: 17553645.
- Ribero D, Abdalla EK, Madoff DC, Donadon M, Loyer EM, Vauthey JN. Portal vein embolization before major hepatectomy and its effects on regeneration, resectability and outcome. Br J Surg 94(11):1386-1394, 2007. PMID: 17583900.
- Tamm EP, Loyer EM, Faria SC, Evans DB, Wolff RA, Charnsangavej C. Retrospective analysis of dual-phase MDCT and follow-up EUS/EUS-FNA in the diagnosis of pancreatic cancer. Abdom Imaging 32(5):660-667, 2007. PMID: 17712589.
- Donadon M, Vauthey JN, Loyer EM, Charnsangavej C, Abdalla EK. Portal thrombosis and steatosis after preoperative chemotherapy with FOLFIRI-Bevacizumab for colorectal liver metastases. World J Gastroenterol 12(40):6556-6558, 2006. PMID: 17072991.
- Tamm EP, Loyer EM, Faria S, Raut CP, Evans DB, Wolff RA, Crane CH, Dubrow RA, Charnsangavej C. Staging of pancreatic cancer with multidetector CT in the setting of preoperative chemoradiation therapy. Abdom Imaging 31(5):568-574, 2006. PMID: 16967235.
- Aloia TA, Vauthey JN, Loyer EM, Ribero D, Pawlik TM, Wei SH, Curley SA, Zorzi D, Abdalla EK. Solitary colorectal liver metastasis: resection determines outcome. Arch Surg 141(5):460-466, discussion 466-467, 2006. PMID: 16702517.
- Hong X, Choi H, Loyer EM, Benjamin RS, Trent JC, Charnsangavej C. Gastrointestinal stromal tumor: role of CT in diagnosis and in response evaluation and surveillance after treatment with Imatinib. Radiographics 26(2):481-495, 2006. PMID: 16549611.
- Pro B, Fayad L, McLaughlin P, Romaguera J, Hagemeister FB, Rodriguez MA, Goy A, Loyer E, Younes A. Pegfilgrastim administered in a single fixed dose is effective in inducing neutrophil count recovery after Paclitaxel and Topotecan chemotherapy in patients with relapsed aggressive non-Hodgkin's lymphoma. Leuk Lymphoma 47(3):481-485, 2006. PMID: 16396772.
- Oki Y, McLaughlin P, Pro B, Hagemeister FB, Bleyer A, Loyer E, Younes A. Phase II study of Oxaliplatin in patients with recurrent or refractory non-Hodgkin lymphoma. Cancer 104(4):781-787, 2005. PMID: 15973667.
- Pawlik TM, Scoggins CR, Zorzi D, Abdalla EK, Andres A, Eng C, Curley SA, Loyer EM, Muratore A, Mentha G, Capussotti L, Vauthey JN. Effect of surgical margin status on survival and site of recurrence after hepatic resection for colorectal metastases. Ann Surg 241(5):715-722, discussion 722-724, 2005. PMID: 15849507.
- Mullen JT, Walsh GL, Abdalla EK, Loyer EM, Curley SA, Vauthey JN. Transdiaphragmatic radiofrequency ablation of liver tumors. J Am Coll Surg 199(5):826-829, 2004. PMID: 15501127.
- Younes A, Pro B, Robertson MJ, Flinn IW, Romaguera JE, Hagemeister F, Dang NH, Fiumara P, Loyer EM, Cabanillas FF, McLaughlin PW, Rodriguez MA, Samaniego F. Phase II clinical trial of interleukin-12 in patients with relapsed and refractory non-Hodgkin's lymphoma and Hodgkin's disease. Clin Cancer Res 10(16):5432-5438, 2004. PMID: 15328181.
- Curley SA, Marra P, Beaty K, Ellis LM, Vauthey JN, Abdalla EK, Scaife C, Raut C, Wolff R, Choi H, Loyer E, Vallone P, Fiore F, Scordino F, De Rosa V, Orlando R, Pignata S, Daniele B, Izzo F. Early and late complications after radiofrequency ablation of malignant liver tumors in 608 patients. Ann Surg 239(4):450-458, 2004. PMID: 15024305.
- Verschraegen CF, Gilbert BE, Loyer E, Huaringa A, Walsh G, Newman RA, Knight V. Clinical evaluation of the delivery and safety of aerosolized liposomal 9-nitro-20(S)-Camptothecin in patients with advanced pulmonary malignancies. Clin Cancer Res 10(7):2319-2326, 2004. PMID: 15073107.
- Bronstein YL, Loyer EM, Kaur H, Choi H, David C, DuBrow RA, Broemeling LD, Cleary KR, Charnsangavej C. Detection of small pancreatic tumors with multiphasic helical CT. AJR Am J Roentgenol 182(3):619-623, 2004. PMID: 14975959.
- Faria SC, Tamm EP, DuBrow R, David C, Loyer EM, Herron D, Sawaf Y, Ball G, Silverman PM, Charnsangavej C. Use of thin-section, multidetector row helical CT images for coronal oblique reformations for optimal visualization of structures in the hepatoduodenal ligament. Abdom Imaging 29(2):231-238, 2004. PMID: 15290952.
- Yovichevich S, Loyer E, Vauthey J-N. Diagnosis please comments [letter]: Drs Loyer and Vauthey respond. Radiology 230(2):595, 2004.
- Verschraegen CF, Kudelka AP, Hu W, Vincent M, Kavanagh JJ, Loyer E, Bastien L, Duggal A, De Jager R. A phase II study of intravenous Exatecan mesylate (DX-8951f) administered daily for 5 days every 3 weeks to patients with advanced ovarian, tubal or peritoneal cancer resistant to platinum, taxane and topotecan. Cancer Chemother Pharmacol 53(1):1-7, 2004. PMID: 14586557.
- Verschraegen CF, Westphalen S, Hu W, Loyer E, Kudelka A, Völker P, Kavanagh J, Steger M, Schulz KD, Emons G. Phase II study of Cetrorelix, a luteinizing hormone-releasing hormone antagonist in patients with platinum-resistant ovarian cancer. Gynecol Oncol 90(3):552-559, 2003. PMID: 13678723.
- Vauthey JN, Loyer E, Chokshi P, Lahoti S. Case 57: eosinophilic cholangiopathy. Radiology 227(1):107-112, 2003. PMID: 12668742.
- Vauthey JN, Loyer EM, Chokshi P, Lahoti S. Case 57. Radiology 225(3):744-745, 2002.
- Vauthey JN, Abdalla EK, Doherty DA, Gertsch P, Fenstermacher MJ, Loyer EM, Lerut J, Materne R, Wang X, Encarnacion A, Herron D, Mathey C, Ferrari G, Charnsangavej C, Do KA, Denys A. Body surface area and body weight predict total liver volume in Western adults. Liver Transpl 8(3):233-240, 2002. PMID: 11910568.
- Koenig TR, Loyer EM, Whitman GJ, Raymond AK, Charnsangavej C. Cystic lymphangioma of the pancreas. AJR Am J Roentgenol 177(5):1090, 2001. PMID: 11641176.
- Verschraegen CF, Kavanagh JJ, Loyer E, Bodurka-Bevers D, Kudelka AP, Hu W, Vincent M, Nelson T, Levenback C. Phase II study of Carboplatin and liposomal Doxorubicin in patients with recurrent squamous cell carcinoma of the cervix. Cancer 92(9):2327-2333, 2001. PMID: 11745287.
- Choi H, Loyer EM, DuBrow RA, Kaur H, David CL, Huang S, Curley S, Charnsangavej C. Radio-frequency ablation of liver tumors: assessment of therapeutic response and complications. Radiographics 21 Spec No:S41-S54, 2001. PMID: 11598247.
- Verschraegen CF, Levenback C, Vincent M, Wolf J, Bevers M, Loyer E, Kudelka AP, Kavanagh JJ. Phase II study of intravenous DX-8951f in patients with advanced ovarian, tubal, or peritoneal cancer refractory to platinum, taxane, and topotecan. Ann N Y Acad Sci 922:349-351, 2000. PMID: 11193920.
- Verschraegen CF, Vincent M, Abbruzzese JL, Siegler D, Kavanagh JJ, Loyer E, Kudelka AP, Rubin E. Phase I study of 9-nitro-20(S)-Camptothecin in combination with Cisplatin for patients with advanced malignancies. Ann N Y Acad Sci 922:345-348, 2000. PMID: 11193919.
- Loyer EM, Fuller L, Libshitz HI, Palmer JL. Radiographic appearance of the chest following therapy for Hodgkin disease. Eur J Radiol 35(2):136-148, 2000. PMID: 10963919.
- Loyer EM, Chin H, DuBrow RA, David CL, Eftekhari F, Charnsangavej C. Hepatocellular carcinoma and intrahepatic peripheral cholangiocarcinoma: enhancement patterns with quadruple phase helical CT-a comparative study. Radiology 212(3):866-875, 1999. PMID: 10478259.
- Ng CS, Loyer EM, Iyer RB, David CL, DuBrow RA, Charnsangavej C. Metastases to the pancreas from renal cell carcinoma: findings on three-phase contrast-enhanced helical CT. AJR Am J Roentgenol 172(6):1555-1559, 1999. PMID: 10350288.
- Verschraegen CF, Gupta E, Loyer E, Kavanagh JJ, Kudelka AP, Freedman RS, Edwards CL, Harris N, Steger M, Steltz V, Giovanella BC, Stehlin JS. A phase II clinical and pharmacological study of oral 9-nitrocamptothecin in patients with refractory epithelial ovarian, tubal or peritoneal cancer. Anticancer Drugs 10(4):375-383, 1999. PMID: 10378672.
- Verschraegen CF, Matei C, Loyer E, Malpica A, Tornos C, Kudelka AP, Kavanagh JJ. Octreotide induced remission of a refractory small cell carcinoma of the endometrium. Int J Gynecol Cancer 9(1):80-85, 1999. PMID: 11240747.
- Corral DA, Amling M, Priemel M, Loyer EM, Fuchs S, Ducy P, Baron R, Karsenty G. Dissociation between bone resorption and bone formation in osteopenic transgenic mice. Proc Natl Acad Sci U S A 95(23):13835-13840, 1998. PMID: 9811887.
- Verschraegen CF, Kudelka AP, Loyer EM, Edwards CL, Freedman RS, Kavanagh JJ. A phase II trial of high-dose Hydroxyurea administered parenterally in patients with epithelial ovarian carcinoma refractory to platinum. Int J Gynecol Cancer 8(6):494-498, 1998.
- Kaur H, Loyer EM, Minami M, Charnsangavej C. Patterns of uterine enhancement with helical CT. Eur J Radiol 28(3):250-255, 1998. PMID: 9881261.
- Kudelka AP, Verschraegen CF, Loyer E. Complete remission of metastatic cervical cancer with the angiogenesis inhibitor TNP-470. N Engl J Med 338(14):991-992, 1998. PMID: 9527612.
- Loyer EM, David C, Sella A, Ellerhorst J. Hyperplasia of axillary nodes in patients undergoing immunotherapy. AJR Am J Roentgenol 169(5):1359-1362, 1997. PMID: 9353459.
- Kudelka AP, Levy T, Verschraegen CF, Edwards CL, Piamsomboon S, Termrungruanglert W, Freedman RS, Kaplan AL, Kieback DG, Meyers CA, Jaeckle KA, Loyer E, Steger M, Mante R, Mavligit G, Killian A, Tang RA, Gutterman JU, Kavanagh JJ. A phase I study of TNP-470 administered to patients with advanced squamous cell cancer of the cervix. Clin Cancer Res 3(9):1501-1505, 1997. PMID: 9815836.
- Wells DC, Loyer EM, Libshitz HI. Carcinoma en cuirasse: uncontrolled local recurrence of breast carcinoma after transverse rectus abdominis myocutaneous flap reconstruction. AJR Am J Roentgenol 169(3):914-915, 1997. PMID: 9275930.
- Kudelka AP, Winn R, Edwards CL, Downey G, Greenberg H, Dakhil SR, Freedman RS, LoCoco S, Umbreit J, Delmore JE, Arbuck S, Loyer E, Gacrama P, Fueger R, Kavanagh JJ. An update of a phase II study of paclitaxel in advanced or recurrent squamous cell cancer of the cervix. Anticancer Drugs 8(7):657-661, 1997. PMID: 9311440.
- Luo G, Ducy P, McKee MD, Pinero GJ, Loyer EM, Behringer RR, Karsenty G. Spontaneous calcification of arteries and cartilage in mice lacking matrix GLA protein. Nature 386(6620):78-81, 1997. PMID: 9052783.
- Libshitz HI, DuBrow RA, Loyer EM, Charnsangavej C. Radiation change in normal organs: an overview of body imaging. Eur Radiol 6(6):786-795, 1996. PMID: 8972312.
- Kudelka AP, Winn R, Edwards CL, Downey G, Greenberg H, Dakhil SR, Freedman RS, Loyer E, Rusinkiewicz J, Gacrama P, Fueger R, Kavanagh JJ. Activity of Paclitaxel in advanced or recurrent squamous cell cancer of the cervix. Clin Cancer Res 2(8):1285-1288, 1996. PMID: 9816298.
- Loyer EM, David CL, Dubrow RA, Evans DB, Charnsangavej C. Vascular involvement in pancreatic adenocarcinoma: reassessment by thin-section CT. Abdom Imaging 21(3):202-206, 1996. PMID: 8661548.
- Loyer EM, DuBrow RA, David CL, Coan JD, Eftekhari F. Imaging of superficial soft-tissue infections: sonographic findings in cases of cellulitis and abscess. AJR Am J Roentgenol 166(1):149-152, 1996. PMID: 8571865.
- Loyer EM, Sahin A, David CL. Granular cell tumor of the breast: sonographic and histologic patterns. Breast Dis 9(2):101-106, 1996.
- Termrungruanglert W, Kudelka AP, Piamsomboon S, Edwards CL, Verschraegen CF, Loyer E, Kavanagh JJ. Remission of recurrent cervical cancer with Paclitaxel and Carboplatin: a case report and review of literature. Eur J Gynaecol Oncol 17(6):493-496, 1996. PMID: 8971525.
- Evans GR, David CL, Loyer EM, Strom E, Waldron C, Ortega R, Ainslie N, Wang B, Janjan N. The long-term effects of internal mammary chain irradiation and its role in the vascular supply of the pedicled transverse rectus abdominis musculocutaneous flap breast reconstruction. Ann Plast Surg 35(4):342-348, 1995. PMID: 8585674.
- Loyer EM, Kaur H, David CL, DuBrow R, Eftekhari FM. Importance of dynamic assessment of the soft tissues in the sonographic diagnosis of echogenic superficial abscesses. J Ultrasound Med 14(9):669-671, 1995. PMID: 7500432.
- Loyer EM, Shabb NS, Mahon TG, Eftekhari F. Fibrous hamartoma of infancy: MR-pathologic correlation. J Comput Assist Tomogr 16(2):311-313, 1992. PMID: 1545033.
- Loyer EM, Kroll SS, David CL, DuBrow RA, Libshitz HI. Mammographic and CT findings after breast reconstruction with a rectus abdominis musculocutaneous flap. AJR Am J Roentgenol 156(6):1159-1162, 1991. PMID: 1827564.
- Eggli KD, Loyer EM, Anderson K. Neonatal pneumatosis cystoides intestinalis caused by volvulus of the mid intestine. Arch Dis Child 64(8):1189-1190, 1989. PMID: 2782937.
- Loyer EM, Eggli KD. Sonographic evaluation of superior mesenteric vascular relationship in malrotation. Pediatr Radiol 19(3):173-175, 1989. PMID: 2654854.
- Cauquil P, Pariente D, Loyer EM, Lallemand D. Aspect echographique singulier d'une distomatose hepatique. J Radiol 67(10):715-717, 1986.
- Loyer EM. Congenital left bronchoesophageal fistula. Semin Roentgenol 21(3):169-171, 1986. PMID: 3726562.
Invited Articles
- Faria SC, Tamm EP, Loyer EM, Szklaruk J, Choi H, Charnsangavej C. Diagnosis and staging of pancreatic tumors. Semin Roentgenol 39(3):397-411, 2004. PMID: 15372753.
- Choi H, Loyer EM, Charnsangavej C. Neoplasms of the liver and the bile ducts. Semin Roentgenol 39(3):412-427, 2004. PMID: 15372754.
- Charnsangavej C, Loyer EM, Iyer RB, Choi H, Kaur H. Tumors of the liver, bile duct and pancreas. Curr Probl Diagn Radiol 29(3):69-108, 2000. PMID: 10875047.
- Loyer EM, Whitman GJ, Fenstermacher MJ. Imaging of ovarian carcinoma. Int J Gynecol Cancer 9(5):351-361, 1999. PMID: 11240793.
- Loyer EM, Delpassand ES. Radiation-induced heart disease: imaging features. Semin Roentgenol 28(4):321-323, 1993. PMID: 8272880.
Abstracts
- Kudelka AP, Verschraegen CF, Loyer E, Wallace S, Gershenson DM, Han J, Ho L, Garzone P, Warner M, Bolton MG, Kavanagh JJ. Preliminary report of a phase I study of escalating dose PG-Paclitaxel (CT-2103) and fixed dose Cisplatin in patients with solid tumors. Proc Am Soc Clin Oncol 21, 2002.
- Lenzi R, Claire V, Andrzey K, Vincent M, Wolff R, Abbruzzese JL, Cristofanilli M, Loyer E, Hu W, Kavanaugh J, Rubin E. New escalation scheme for phase I study of drug combination: 9-nitro-20(S)-camptothecin (RFS 2000) with Cisplatin for patients (pts) with advanced malignancies. Proc Am Soc Clin Oncol 21, 2002.
- Verschraegen C, Vincent M, Abbruzzese J, Seigler D, Kavanagh J, Loyer E, Kudelka A, Rubin E. Phase I study of 9-nitro-20(S)-camptothecin (RFS 2000) in combination with Cisplatin for patients with advanced malignancies. Proc Am Soc Clin Oncol 19, 2000.
- Kudelka A, Verschraegen C, Vincent M, Levenback C, Wolf J, Bevers M, Loyer E, Brown N, Kavanagh J. Phase II study of intravenous DX-8951f in patients (pts) with advanced ovarian, tubal, or peritoneal cancer refractory to platinum, taxane, and topotecan. Proc Am Soc Clin Oncol 19, 2000.
Book Chapters
- Yedururi S, Salem UI, Avritscher R, Loyer EM. Imaging Response Evaluation. In: Colorectal Liver Metastasis. 1. Springer, Cham, 417-439, 2022.
- Choi H, Loyer E, Kaur H, Silverman PM. Imaging Neoplasms of the Abdomen and Pelvis. In: Cancer Medicine. 7. B. C. Decker: Baltimore, 474-478, 2005.
- Choi H, Loyer E, Charnsangavej C. Radiographic Imaging Following Radiofrequency Ablation of Liver Tumors. In: Radiofrequency Ablation of Cancer: Current Indications, Techniques and Outcomes. Springer-Verlag: New York, 253-268, 2004.
- Iyer, RB, Loyer E, Munden RF, Libshitz HI. Effects of Treatment on Normal Tissues: The Thorax. In: Imaging in Oncology. 2. Taylor & Francis: London; Boca Raton, 2004.
- Tamm EP, Szklaruk J, Loyer E, Faria SC, Charnasangavej C. Radiographic Imaging: CT/MR/PET. In: Pancreatic Cancer. 1. Jones and Bartlett: Sudbury, 165-180, 2004.
- Choi H, Loyer EM, Kaur H, Silverman PM. Imaging Neoplasms of the Abdomen and Pelvis. In: Cancer Medicine. 6. B.C. Decker: Baltimore, 523-527, 2003.
- Kaur H, Loyer E, Lano EA, Charnsangavej C. Pancreatic Cancer: Radiologic Staging. In: Pancreatic Cancer: M.D. Anderson Solid Tumor Oncology Series. Springer-Verlag: New York, 85-95, 2002.
- Libshitz HI, Iyer RB, Loyer EM. Effects of Treatment on Normal Tissues: The Thorax. In: Imaging in Oncology. Isis Medical Media: Oxford, 1997.
Letters to the Editor
- Aloia TA, Loyer E. Fancier and more expensive doesn't mean better: an argument for CT staging of patients with colorectal liver metastases. Ann Surg Oncol 24: 603-604, 2017.
Patient Reviews
CV information above last modified August 07, 2024