Feng Yin, MD, PhD.
Department of Anatomical Pathology, Division of Pathology-Lab Medicine Div
About Dr. Feng Yin
I am an Associate Professor of Pathology with special interests in gastrointestinal, liver, and pancreatic pathology. My clinical interests include neoplastic gastrointestinal, hepatic, and pancreatic diseases, gastrointestinal inflammatory disorders, and non-neoplastic diseases of the liver. I have a broad background in basic, translational, and clinical cancer research. One of my research interests focuses is on the Hippo-YAP tumor suppressor pathway, an emerging cancer signaling pathway, in human digestive system cancers. In addition, I am interested in developing diagnostic, prognostic, and therapeutic biomarkers for digestive system cancers.
Present Title & Affiliation
Primary Appointment
Associate Professor (Joint Appointment), Department of Translational Molecular Pathology, The University of Texas MD Anderson Cancer Center
Associate Professor, Department of Pathology, The University of Texas MD Anderson Cancer Center, Houston, Texas
Education & Training
Degree-Granting Education
| 2003 | Peking University Health Science Center, Beijing, Beijing, CN, Pathology and Pathophysiology, PhD |
| 1999 | Hunan Medical University, Changsha, Hunan, CN, Physiology, MS |
| 1996 | Medical College of Nanchang University, Nanchang, Jiangxi, CN, Clinical Medicine, MD |
Postgraduate Training
| 2018-2019 | Clinical Fellowship, Gastrointestinal and Liver Pathology, University of Florida College of Medicine, Gainesville, Florida |
| 2014-2018 | Clinical Residency, Anatomic and Clinical Pathology, University of Oklahoma Health Science Center, Oklahoma City, Oklahoma |
| 2006-2011 | Research Fellowship, Molecular Biology and Genetics, Johns Hopkins University School of Medicine, Baltimore, Maryland |
| 2003-2005 | Research Fellowship, Physiology, Indiana University School of Medicine, Indianapolis, Indiana |
Licenses & Certifications
| 2022 | Texas Medical Board |
| 2019 | Missouri Board of Registration for the Healing Arts |
| 2018 | American Board of Pathology |
| 2018 | Florida Board of Medicine |
| 2016 | Oklahoma State Board of Medical Licensure and Supervision |
Experience & Service
Faculty Academic Appointments
Assistant Professor, Department of Translational Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX, 2023 - 2025
Assistant Professor, Department of Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX, 2022 - 2025
Assistant Professor, Department of Pathology and Anatomical Sciences, University of Missouri School of Medicine, Columbia, MO, 2019 - 2022
Research Specialist, Department of Molecular biology and genetics, Howard Hughes Medical Institute, Johns Hopkins University, Baltimore, MD, 2012 - 2014
Administrative Appointments/Responsibilities
Rotation Site Director, GI and liver pathology fellowship, Department of Pathology, The University of Texas MD Anderson Cancer Center, Houston, Texas, 2025 - Present
Program Director, Gastrointestinal and Liver Pathology Fellowship, Department of Pathology, The University of Texas MD Anderson Cancer Center, 2025 - Present
Extramural Institutional Committee Activities
Member, Program Evaluation Committee (PEC) (Gastrointestinal & Liver Pathology Fellowship), Department of Pathology, The University of Texas MD Anderson Cancer Center, 2024 - Present
Member, Clinical Competency Committee (CCC) (Gastrointestinal & Liver Pathology Fellowship), Department of Pathology, The University of Texas MD Anderson Cancer Center, 2024 - Present
Member, Institutional Tissue Bank (ITB) Internal Advisory Committee, The University of Texas MD Anderson Cancer Center, 2024 - 2025
Member, Clinical Competency Committee (CCC) (Surgical Pathology Fellowship), Department of Pathology, The University of Texas MD Anderson Cancer Center, 2024 - 2025
Member, Faculty Senate, The University of Texas MD Anderson Cancer Center, 2024 - 2025
Member, Program Evaluation Committee (PEC) (Surgical Pathology Fellowship), Department of Pathology, The University of Texas MD Anderson Cancer Center, 2024 - 2025
Member, Fellow Unknown Case Conference Review Committee (Surgical Pathology Fellowship), Department of Pathology, The University of Texas MD Anderson Cancer Center, 2023 - 2024
Member, Clinical Competency Committee (Pathology Residency Program), Department of Pathology and Anatomical Sciences, University of Missouri School of Medicine, 2019 - 2022
Editorial Activities
Editorial board member, World Journal of Clinical Cases, 2022 - Present
Editorial board member, Gastroenterology Research, 2021 - 2024
Honors & Awards
| 2025 | GIPS Abstract Award (As the Mentor), Rodger C. Haggitt Gastrointestinal Pathology Society |
| 2025 | GoPath Best Abstract Award (first prize) (As the Mentor), Chinese American Pathologists Association (CAPA) |
| 2024 | 2nd Place for Poster Presentation Award: Clinical Research, 2024 DPLM Research Day Awards (As the Mentor), Division of Pathology and Laboratory Medicine, The University of Texas MD Anderson Cancer Center |
| 2024 - 2025 | DPLM Research Fund Award, Division of Pathology and Laboratory Medicine, The University of Texas MD Anderson Cancer Center |
| 2023 | The William O. Russell Faculty Research Award, Department of Pathology, The University of Texas MD Anderson Cancer Center |
| 2023 - 2024 | DPLM Research Fund Award, Division of Pathology and Laboratory Medicine, The University of Texas MD Anderson Cancer Center |
| 2022 | Excellence in Research travel grant (As the Mentor), Missouri Society of Pathologists |
| 2021 | Paul Sun MD Distinguished Faculty Award for Outstanding Contribution to Teaching, Department of Pathology and Anatomic sciences, University of Missouri |
| 2020 - 2022 | Early Career Faculty Research Development Fellowship, University of Missouri |
| 2019 | GoPath Best Abstract Award, Chinese American Pathologists Association (CAPA) |
| 2004 | Excellent Doctor Thesis Award, Peking University |
Professional Memberships
Selected Presentations & Talks
Regional Presentations
- 2026. Challenges and Pitfalls in Diagnosing Neuroendocrine Neoplasms of the Digestive System. Invited.
National Presentations
- 2023. Clinicopathologic features of gastrointestinal endometriosis and endosalpingiosis. Poster. CAP (College of American Pathologists) Annual meeting 2023. Chicago, IL, US.
- 2022. Gastric Spindle Cell Leiomyosarcoma Is Associated With Chronic Helicobacter pylori Infection. Poster. ACG Annual Meeting 2022. Charlotte, SC, US.
- 2022. Monoclonal Immunoglobulin Deposition Disease: A Rare Case of Acute Liver Failure. Poster. ACG (American College of Gastroenterology) Annual Meeting 2022. Charlotte, SC, US.
- 2022. An Uncommon Cause for Common Symptoms of Abdominal Pain and Diarrhea: A Case Report of Human Intestinal Spirochetosis in an Immune-Competent Patient. Poster. ACG (American College of Gastroenterology) Annual Meeting 2022. Charlotte, SC, US.
- 2022. Update on Dysplasia in Upper GI Tract. Invited. The 8th Annual CAPA Diagnostic Course. Virtual, US.
- 2022. Epithelial Tumors of the Esophagus and Stomach. Invited. CAPA (Chinese American Pathologists Association) Online Education Program Pathology Lecture Series. Virtual, US.
- 2021. Esophagitis Dissecans Superficialis Associated With Lymphoma. Poster. ACG Annual Meeting 2021. Las Vegas, NV, US.
- 2021. A Rare Cause of Dysphagia: Polypoidal Esophageal Masses From Poorly Differentiated Thymic Cancer. Poster. ACG Annual Meeting 2021. Las Vegas, NV, US.
- 2021. A Rare Case of Ectopic Pancreas Spotted as a Small Nodularity in Distal Esophagus. Poster. ACG Annual Meeting 2021. Las Vegas, NV, US.
- 2021. Xanthogranulomatous Inflammation of The Uterus Presenting as A Mass Lesion: A Rare Case Report. Poster. CAP Annual Meeting 2021. Chicago, IL, US.
- 2021. Gastric Amyloidosis Presenting as Gastrointestinal Bleeding: Case Report and Concise Review. Poster. CAP Annual Meeting 2021. Chicago, IL, US.
- 2020. Doxycycline-Induced Gastric Mucosal Injury: A Rare Diagnosis. Poster. ACG Annual Meeting 2020. Virtual, US.
- 2020. Russell Body Esophagitis with Gastritis: A Rare Case Report. Poster. CAP Annual Meeting 2020. Virtual, US.
- 2020. Human Papillomavirus–Related Anorectal Adenocarcinoma. Poster. CAP Annual Meeting 2020. Virtual, US.
- 2020. A Rare Case of Hyperplastic Polyp of Esophagus on a Schatzki’s Ring. Poster. ACG Annual Meeting 2020. Virtual, US.
- 2020. A 3-Case Report Study of Esophageal Hyperplastic Polyp: Clinicopathologic Findings and Literature Review. Poster. CAP Annual Meeting 2020. Virtual, US.
- 2020. A six-case review of granular cell tumor in a rare location (colon) of the gastrointestinal tract. Poster. CAP Annual Meeting 2020. Virtual, US.
- 2020. Russell Body Duodenitis in A Patient with Duodenal Adenoma and High-Grade Dysplasia. Poster. ASCP Annual Meeting 2020. Virtual, US.
- 2015. Educational value of digital whole slides accompanying published online pathology journal articles: A multi-institutional study. Invited. Pathology Visions 2015. Boston, MA, US.
- 2015. Hypertrophic hyalinizing vasculopathy presenting as a cerebellar mass. Poster. CAP Annual Meeting 2015. Nashville, TN, US.
- 2015. An Evaluation of the HemoCue Assay for the Rapid Assessment of Plasma Free Hemoglobin (PfHb) in Pediatric Patients Undergoing Extracorporeal Membrane Oxygenation (ECMO). Poster. AACC Annual Meeting 2015. Atlanta, GA, US.
International Presentations
- 2026. Challenges and Pitfalls in Diagnosing Neuroendocrine Neoplasms of the Digestive System. Invited.
- 2026. Infectious Diseases of the GI Tract: A Surgical Pathology Perspective. Invited.
- 2025. SEL1L-NTRK1 is a recurrent gene fusion in pancreatic acinar cell carcinoma with potential therapeutic significance. Poster. Vienna, AT.
- 2025. YAP Expression in Sporadic and Inflammatory Bowel Disease-Associated Colorectal Cancer. Poster. Vienna, AT.
- 2025. Poorly Differentiated Gastric Adenocarcinoma: Clinicopathological and Molecular Profiling of the Subtypes. Conference. Boston, US.
- 2025. Clinicopathologic and Molecular Analysis of Pancreatic Ductal Adenocarcinoma with Methylthioadenosine Phosphorylase Genomic Loss. Conference. Boston, US.
- 2025. Expanding Continuing Pathology Education Beyond One Institution: Utilization of Zoom for Cost-Effective Regional Pathology Case Sharing. Conference. Boston, US.
- 2025. A Comparative Study of Claudin 18.2 Expression in Sporadic and Inflammatory Bowel Disease-Associated Colorectal Cancer. Conference. Boston, US.
- 2025. Clinicopathologic and Molecular Analysis of Hepatocellular Carcinoma with RB1 Mutations/Deletions: A Distinct Non-Chromophobe Subset Featuring Abrupt Anaplasia. Conference. Boston, US.
- 2025. Clinicopathologic and Molecular Analysis of Hepatocellular Carcinoma with Methylthioadenosine Phosphorylase (MTAP) Genomic Loss. Conference. Boston, US.
- 2024. Molecular Profiling of Colonic Mucinous Carcinoma with Signet Ring Cell Features. Poster. Baltimore, US.
- 2024. Molecular and Clinicopathologic Analysis of Colorectal Adenocarcinoma with Pancreatobiliary-Like Morphology and Immunoprofile. Conference. Baltimore, US.
- 2024. The Expression of the NF2 Gene as a Novel Prognostic Biomarker for Gastric Adenocarcinoma. Poster. Baltimore, US.
- 2024. Molecular and Clinicopathologic Analysis of Hepatocellular Carcinoma with Homologous Recombination Deficiency. Conference. Baltimore, US.
- 2024. Molecular and Clinicopathologic Analysis of Gastroesophageal Carcinoma with Paneth Cell-Like Features. Poster. Baltimore, US.
- 2023. Clinicopathologic and Molecular Analysis of Gastric Carcinoma With Homologous Recombination Deficiency. Conference. New Orleans, US.
- 2023. Distinct Clinicopathologic and Molecular Subgroups in Colorectal Adenocarcinoma. Poster. New Orleans, US.
- 2023. Hepatocellular Carcinoma with Foamy Histiocyte-Like Features: A Contemporary Clinicopathologic Analysis of Five Cases with Molecular Profile Study. Poster. New Orleans, US.
- 2023. Molecular and Clinicopathologic Analysis of Hepatocellular Carcinomas With Aberrant CDX2, SATB2, CK20 and CK19 Expression. Poster. New Orleans, US.
- 2022. Somatic Mutations in FAT Cadherin Family Members Constitute an Underrecognized Subtype of Colorectal Adenocarcinoma with Favorable Clinicopathologic Features. Poster. Los Angeles, US.
- 2021. Normal Duodenal Histology in Cases with Abnormal Celiac Serology: Dilemma in Gastroenterology Practices. Poster. Virtual, US.
- 2020. Double Negative for Expression of YAP1 and CDX2 Defines a Subgroup of Colitis-Associated Colorectal Cancer with Early Onset and Aggressive Features. Poster. Los Angeles, US.
- 2020. Correlation between the Tumor budding and Tumor Microenvironment in Pancreatic ductal adenocarcinoma. Poster. Los Angeles, US.
- 2020. Deleterious mutations in esophageal carcinoma cuniculatum detected by next generation sequencing. Poster. Los Angeles, US.
- 2019. Yes-Associated Protein 1 (YAP1) is a Novel Progressive Marker for Early Stage Esophageal Adenocarcinoma. Poster. National Harbor, US.
- 2019. Splenic arterial involvement is associated with poor prognosis in resected distal pancreatic cancer. Poster. National Harbor, US.
- 2019. Challenges in interpreting early Barrett adenocarcinoma in endoscopic submucosal dissection specimens. Poster. National Harbor, US.
- 2019. Identification of racial-specific novel mutations in pancreatic ductal adenocarcinoma by whole-exome sequencing: comparison of African American patients to Caucasian patients. Poster. National Harbor, US.
- 2019. Comparison and Validation of AJCC 7th and 8th Editions of TNM Staging in Resectable Distal Pancreatic Cancer. Poster. National Harbor, US.
- 2018. Reduction of BCR-ABL ordering errors through multipronged quality improvement interventions. Poster. Vancouver, CA.
- 2018. Vascular Tumors of the Adrenal Gland: A Multi-institutional Clinicopathologic Analysis of 27 Cases. Poster. Vancouver, CA.
Formal Peers
- 2026. Challenges and Pitfalls in Diagnosing Neuroendocrine Neoplasms of the Digestive System. Houston, Texas, US.
- 2026. Challenges and Pitfalls in Diagnosing Neuroendocrine Neoplasms of the Digestive System.
- 2026. Infectious Diseases of the GI Tract: A Surgical Pathology Perspective.
- 2026. Infectious Diseases of the GI Tract: A Surgical Pathology Perspective, US.
- 2022. Update on Dysplasia in Upper GI Tract, US.
- 2022. Dissecting Hippo-YAP Signaling for Targeted Cancer Therapy. Invited, US.
- 2022. Epithelial Tumors of the Esophagus and Stomach, US.
Grant & Contract Support
| Date: | 2026 - 2031 |
| Title: | Chromatin mechanisms underlying KDM2A-dependent malignant epithelial states in gastric adenocarcinoma |
| Funding Source: | NIH |
| Role: | Consult |
| Date: | 2025 - 2030 |
| Title: | Functional Characterization of the Lineage Plasticity Landscape of Cholangiocarcinoma |
| Funding Source: | NIH |
| Role: | Key |
| Date: | 2025 - 2030 |
| Title: | Understanding Role of Histone Demethylase KDM2A in Gastric Adenocarcinoma |
| Funding Source: | NIH |
| Role: | Co-I |
| Date: | 2025 - 2028 |
| Title: | Role of Reactive Oxygen Species in PDAC Development |
| Funding Source: | Cancer Prevention & Research Institute of Texas (CPRIT) |
| Role: | Co-I |
| Date: | 2024 - 2029 |
| Title: | Mechanisms of CDH1-Inactivated Advanced Gastric Adenocarcinoma Tumorigenesis |
| Funding Source: | NIH |
| Role: | Key |
| Date: | 2023 |
| Title: | Targeting the CCDC43-YAP Axis in Hepatocellular Carcinoma |
| Funding Source: | NIH/NCI |
| Role: | PI |
| Date: | 2023 |
| Title: | Molecular Regulation of Tumor Suppressor NF2/Merlin |
| Funding Source: | Institutional Research Grant (IRG) Program |
| Role: | PI |
| Date: | 2006 - 2014 |
| Title: | Functional Characterization of a Novel NF2/Merlin Protein Complex in Growth Control |
| Funding Source: | Department of Defense (DOD) |
| Role: | Postdoctoral Fellow |
| ID: | NF093145 |
| Date: | 2004 - 2014 |
| Title: | Control of Cell Number in Developing Retina |
| Funding Source: | NIH/NEI |
| Role: | Postdoctoral Fellow |
| ID: | R01EY015708 |
| Date: | 2004 - 2007 |
| Title: | Synthetic smooth muscle cell-selective promoters |
| Funding Source: | NIH/NIDDK |
| Role: | Postdoctoral Fellow |
| ID: | R01DK065644 |
| Date: | 2001 - 2012 |
| Title: | Regulation of visceral smooth muscle-specific gene expression during development |
| Funding Source: | NIH/NIDDK |
| Role: | Postdoctoral Fellow |
| ID: | 5R01DK061130 |
| Date: | 1998 - 2006 |
| Title: | Telokin Gene Regulation in Smooth Muscle |
| Funding Source: | NIH/NHLBI |
| Role: | Postdoctoral Fellow |
| ID: | R01HL058571 |
Selected Publications
Peer-Reviewed Articles
- Zou G, Yoshimura K, Fan Y, Zeng L, Bhati AS, Vanpariya BR, Dai E, Yamashita K, Wang L, Wu J, Shao S, Scott AW, Jin J, Pizzi MP, Yao X, Brown CA, Cao F, Wang R, Han X, Li J, Chen H, Wang P, Wang L, Liu B, Zhou J, Lo YH, Gan Q, Waters R, Yin F, Song S, Ajani JA, Dhar SS. Pharmacologic inhibition of SOX9-CDK4 by CYD-4-61 impairs gastric adenocarcinoma growth and amplifies anti-PD-1 response. Cancer Letters, 2026. e-Pub 2026. PMID: 42567470.
- Song S, Fan Y, Zou G, Hou L, Li Y, Wang R, Dai E, Jin J, Scott AW, Shao S, Pizzi MP, Vykoukal JV, Katayama H, Hanash S, Calin GA, Zhang X, Lee MG, Wang Z, Lo YH, Gan Q, Waters RE, Yin F, Wang L, Cheng X, Ajani JA, Dhar SS. KAP1 promotes gastric adenocarcinoma progression by activating Hippo/YAP1 signaling via binding to HNRNPAB. Cancer Letters 621, 2025. e-Pub 2025. PMID: 40189014.
- Yoshimura K, Zou G, Fan Y, Yamashita K, Wang L, Wu J, Wang R, Shao S, Scott AW, Jin J, Pizzi MP, Yao X, Brown CA, Wang L, Gan Q, Waters R, Yin F, Song S, Dhar SS, Ajani JA. HSP90 inhibitor AUY922 suppresses tumor growth and modulates immune response through YAP1-TEAD pathway inhibition in gastric cancer. Cancer Letters 610, 2025. e-Pub 2025. PMID: 39603381.
- Lawson NM, Ye L, Cho CY, Zhao B, Mitchell T, Yin F, Akdemir KC. Recurrent ERBB2 alterations are associated with esophageal adenocarcinoma brain metastases. medRxiv, 2025. e-Pub 2025. PMID: 40061311.
- Sewastjanow-Silva M, Kwiatkowski E, Yamashita K, Abdelhakeem A, Yoshimura K, Vicentini ER, Pizzi MP, Jin J, Fan Y, Zou G, Wang L, Yin F, Dhar SS, Murphy MP, Mares JE, Li JJ, Gan Q, Waters RE, Rogers JE, Ajani JA. Three biomarkers (HER2, PD-L1, and microsatellite status) in a large cohort of metastatic gastroesophageal adenocarcinomas: The MD Anderson Cancer Center experience. International journal of cancer 155(12):2277-2286, 2024. e-Pub 2024. PMID: 38995150.
- Majzoub AM, Yousaf MN, Yin F, Tahan V. A very rare case of isolated collagenous duodenitis. Gastrointestinal endoscopy 98(3):457-458, 2023. e-Pub 2023. PMID: 37142153.
- Gandhi M, Pasha SB, Reznicek E, Pasha SR, Ertugrul H, Araslanova A, Yin F, Tahan V. A Case of Light Chain Deposition Disease Leading to Acute Liver Failure and Review of Literature. Diseases 11(1), 2023. e-Pub 2023. PMID: 36810539.
- Ijaz K, Yin F. Papillary Thyroid Carcinoma With Squamous Dedifferentiation: A Potential Diagnostic Pitfall. Anticancer Res 43(1):255-258, 2023. e-Pub 2023. PMID: 36585182.
- Wang LL, Zheng W, Liu XL, Yin F. Somatic mutations in FAT cadherin family members constitute an underrecognized subtype of colorectal adenocarcinoma with unique clinicopathologic features. World Journal of Clinical Oncology 13(10):779-788, 2022. e-Pub 2022. PMID: 36337316.
- Zeng Y, Yin L, Zhou J, Zeng R, Xiao Y, Black AR, Hu T, Singh PK, Yin F, Batra SK, Yu F, Chen Y, Dong J. MARK2 regulates chemotherapeutic responses through class IIa HDAC-YAP axis in pancreatic cancer. Oncogene 41(31):3859-3875, 2022. e-Pub 2022. PMID: 35780183.
- Hu S, Alpert L, Cates JMM, Stratification Group RGR, Gonzalez RS. Gastrointestinal stromal tumors (GISTs) arising in uncommon locations: clinicopathologic features and risk assessment of esophageal, colonic, and appendiceal GISTs. Mod Pathol 35(4):554-563, 2022. e-Pub 2022. PMID: 34702994.
- Yin, F, Wang, K, Hu, MM, Starostik, P, Newsom, KJ, Liu, X. Deleterious mutations in esophageal carcinoma cuniculatum detected by next generation sequencing. International journal of clinical and experimental pathology 15(1):38-45, 2022. e-Pub 2022.
- Yin F, Wang K, Hu M, Starostik P, Newsom KJ, Liu X. Deleterious mutations in esophageal carcinoma cuniculatum detected by next generation sequencing. Int J Clin Exp Pathol 15(1):38-45, 2022. e-Pub 2022. PMID: 35145582.
- Yin F, Saad M, Lin J, Jackson CR, Ren B, Lawson C, Karamchandani DM, Bernabeu BQ, Jiang W, Dhir T, Zheng R, Schultz CW, Zhang D, Thomas CL, Zhang X, Lai J, Schild M, Zhang X, Xie H, Liu X. Splenic-vasculature involvement is associated with poor prognosis in resected distal pancreatic cancer. Gastroenterol Rep (Oxf) 9(2):139-145, 2021. e-Pub 2021. PMID: 34026221.
- Tarar ZI, Tahan V, Yin F, Daglilar E. An Unusual Case of Esophageal Hyperplastic Polyp with Scleroderma: A Case Report and Review of the Literature. Cureus 13(1):e12500, 2021. e-Pub 2021. PMID: 33564508.
- Yin F, Xie H, Lai J, Chen Y, Dong J, Zhang X, Liu X. Double Negativity for Expression of YAP1 and CDX2 Defines an Aggressive Type of Colitis-associated Cancer. Anticancer Res 40(10):5411-5416, 2020. e-Pub 2020. PMID: 32988861.
- Arshi J, Nguyen J, Yin F. Russell Body Gastroesophagitis Concurrent With Barrett's Esophagus. Anticancer Res 40(7):3991-3994, 2020. e-Pub 2020. PMID: 32620642.
- Yin F, Saad M, Xie H, Lin J, Jackson CR, Ren B, Lawson C, Karamchandani DM, Bernabeu BQ, Jiang W, Dhir T, Zheng R, Schultz CW, Zhang D, Thomas CL, Zhang X, Lai J, Schild M, Zhang X, Liu X. Validation of American Joint Committee on Cancer 8th edition of TNM staging in resected distal pancreatic cancer. World J Gastrointest Pharmacol Ther 11(2):25-39, 2020. e-Pub 2020. PMID: 32550043.
- Arshi J, Sauer M, Yin F. Rapid Sarcomatoid Transformation of Lung Squamous Cell Carcinoma After Neoadjuvant Therapy: A Case Report. Anticancer Res 40(3):1625-1629, 2020. e-Pub 2020. PMID: 32132066.
- Zheng W, Goodman AL, Velázquez Vega JE, Yin F, Fung KM, Osunkoya AO. Metastatic Renal Cell Carcinoma to the Brain: A Contemporary Clinicopathologic Analysis With Comparison of Immunohistochemical Profiles to Selected Primary Brain Tumors With Clear Cell Features. Appl Immunohistochem Mol Morphol 28(5):395-402, 2020. e-Pub 2020. PMID: 30882396.
- Crowe A, Zheng W, Miller J, Pahwa S, Alam K, Fung KM, Rubin E, Yin F, Ding K, Yue W. Characterization of Plasma Membrane Localization and Phosphorylation Status of Organic Anion Transporting Polypeptide (OATP) 1B1 c.521 T>C Nonsynonymous Single-Nucleotide Polymorphism. Pharm Res 36(7):101, 2019. e-Pub 2019. PMID: 31093828.
- Yin F, Zheng W, Lucas MD, Allen RA, Zhou Y. Using the EPIDEM Model of Quality Improvement to Increase Value of BCR-ABL1 Tests. Am J Clin Pathol 151(1):68-74, 2019. e-Pub 2019. PMID: 30212872.
- Hu M, Liu W, Yin F, Zhang D, Liu X, Lai J. Liver Metastasis of Hepatoid Colonic Adenocarcinoma: A Rare and Unusual Entity With Poor Prognosis and Review of the Literature. Gastroenterology Res 11(6):430-435, 2018. e-Pub 2018. PMID: 30627268.
- Yin F, Piao J, Liu X, Lai J. Foamy Histiocyte-like Esophageal Adenocarcinoma: Unusual Morphology and Diagnostic Pitfalls. Anticancer Res 38(10):5999-6002, 2018. e-Pub 2018. PMID: 30275231.
- Yin F, Han G, Bui MM, Gibbs J, Martin I, Sundharkrishnan L, King L, Jabcuga C, Stuart LN, Hassell LA. Educational Value of Digital Whole Slides Accompanying Published Online Pathology Journal Articles: A Multi-Institutional Study. Arch Pathol Lab Med 140(7):694-7, 2016. e-Pub 2016. PMID: 27116087.
- Liu B, Zheng Y, Yin F, Yu J, Silverman N, Pan D. Toll Receptor-Mediated Hippo Signaling Controls Innate Immunity in Drosophila. Cell 164(3):406-19, 2016. e-Pub 2016. PMID: 26824654.
- Qing Y, Yin F, Wang W, Zheng Y, Guo P, Schozer F, Deng H, Pan D. The Hippo effector Yorkie activates transcription by interacting with a histone methyltransferase complex through Ncoa6. Elife 3(July2014):1-13, 2014. e-Pub 2014. PMID: 25027438.
- Yin F, Yu J, Zheng Y, Chen Q, Zhang N, Pan D. Spatial organization of Hippo signaling at the plasma membrane mediated by the tumor suppressor Merlin/NF2. Cell 154(6):1342-55, 2013. e-Pub 2013. PMID: 24012335.
- Koontz LM, Liu-Chittenden Y, Yin F, Zheng Y, Yu J, Huang B, Chen Q, Wu S, Pan D. The Hippo effector Yorkie controls normal tissue growth by antagonizing scalloped-mediated default repression. Dev Cell 25(4):388-401, 2013. e-Pub 2013. PMID: 23725764.
- Ling C, Zheng Y, Yin F, Yu J, Huang J, Hong Y, Wu S, Pan D. The apical transmembrane protein Crumbs functions as a tumor suppressor that regulates Hippo signaling by binding to Expanded. Proc Natl Acad Sci U S A 107(23):10532-7, 2010. e-Pub 2010. PMID: 20498073.
- Xu Q, Xu N, Zhang T, Zhang H, Li Z, Yin F, Lu Z, Han Q, Zhang Y. Mammalian tolloid alters subcellular localization, internalization, and signaling of alpha(1a)-adrenergic receptors. Mol Pharmacol 70(2):532-41, 2006. e-Pub 2006. PMID: 16690783.
- Yin F, Hoggatt AM, Zhou J, Herring BP. 130-kDa smooth muscle myosin light chain kinase is transcribed from a CArG-dependent, internal promoter within the mouse mylk gene. Am J Physiol Cell Physiol 290(6):C1599-609, 2006. e-Pub 2006. PMID: 16407417.
- Yin F, Wang YY, Du JH, Li C, Lu ZZ, Han C, Zhang YY. Noncanonical cAMP pathway and p38 MAPK mediate beta2-adrenergic receptor-induced IL-6 production in neonatal mouse cardiac fibroblasts. J Mol Cell Cardiol 40(3):384-93, 2006. e-Pub 2006. PMID: 16466739.
- Yin F, Herring BP. GATA-6 can act as a positive or negative regulator of smooth muscle-specific gene expression. J Biol Chem 280(6):4745-52, 2005. e-Pub 2005. PMID: 15550397.
- Wang Y, Hou R, Li P, Li J, Yan J, Yin F, Han C, Zhang Y. Gene expression profiles in response to the activation of adrenoceptors in A7r5 aortic smooth muscle cells. Clin Exp Pharmacol Physiol 31(9):602-7, 2004. e-Pub 2004. PMID: 15479167.
- Li P, Li JL, Feng XH, Li ZP, Yin F, Yan J, Hou R, Han QD, Zhang YY. [Comparison of changes in left ventricular gene expression profiles from different cardiac hypertrophy models in rats]. Sheng Li Xue Bao 56(2):210-8, 2004. e-Pub 2004. PMID: 15127132.
- Yin F, Zhu Y, Li P, Han QD, Zhang YY. [Isoproterenol-induced activation of MAPK, NFkappaB and JAK/STAT pathway in mouse myocardium]. Sheng Li Xue Bao 55(4):449-53, 2003. e-Pub 2003. PMID: 12937826.
- Yin F, Lu ZZ, Han QD, Zhang YY. [Expression of beta2-adrenergic receptor and its effect on the proliferation of neonatal rat cardiac fibroblasts]. Sheng Li Xue Bao 55(3):251-4, 2003. e-Pub 2003. PMID: 12817289.
- Li P, Li JL, Yin F, Yan J, Feng XH, Li ZP, Han QD, Zhang YY. [Alterations of Axin protein expression during cardiac remodeling in rats]. Sheng Li Xue Bao 55(3):331-5, 2003. e-Pub 2003. PMID: 12817302.
- Yin F, Li P, Zheng M, Chen L, Xu Q, Chen K, Wang YY, Zhang YY, Han C. Interleukin-6 family of cytokines mediates isoproterenol-induced delayed STAT3 activation in mouse heart. J Biol Chem 278(23):21070-5, 2003. e-Pub 2003. PMID: 12665506.
Review Articles
- Ali AH, Nallapeta NS, Yousaf MN, Petroski GF, Sharma N, Rao DS, Yin F, Davis RM, Bhat A, Swi AIA, Al-Juboori A, Ibdah JA, Hammoud GM. EUS-guided versus percutaneous liver biopsy: A prospective randomized clinical trial. Endoscopic Ultrasound 12(2):171-180, 2023. e-Pub 2023. PMID: 37693114.
- Smith C, Zheng W, Dong J, Wang Y, Lai J, Liu X, Yin F. Tumor microenvironment in pancreatic ductal adenocarcinoma: Implications in immunotherapy. World J Gastroenterol 28(27):3297-3313, 2022. e-Pub 2022. PMID: 36158269.
- Yin F, Wu ZH, Lai JP. New insights in diagnosis and treatment of gastroenteropancreatic neuroendocrine neoplasms. World J Gastroenterol 28(17):1751-1767, 2022. e-Pub 2022. PMID: 35633912.
- Yin, F, Zheng, W, Amofa-Ho, S, Liu, X. Histomorphology and Molecular Profiling of Well-Differentiated Squamous Cell Carcinoma of the Esophagus Including its Unusual Variants. Journal of Clinical and Translational Pathology 2(3):75-82, 2022. e-Pub 2022.
- Yin F, Dong J, Kang LI, Liu X. Hippo-YAP signaling in digestive system tumors. Am J Cancer Res 11(6):2495-2507, 2021. e-Pub 2021. PMID: 34249412.
- Yin, F, Hernandez Gonzalo, D, Lai, JP, Liu, X. Histopathology of Barrett’s Esophagus and Early-Stage Esophageal Adenocarcinoma. Gastrointestinal Disorders 1(1):147-163, 2019. e-Pub 2019.
- Herring BP, El-Mounayri O, Gallagher PJ, Yin F, Zhou J. Regulation of myosin light chain kinase and telokin expression in smooth muscle tissues. Am J Physiol Cell Physiol 291(5):C817-27, 2006. e-Pub 2006. PMID: 16774989.
Professional Educational Materials
- Yu H, Yin F. Cholangiocarcinoma, solid, tubulocystic variant (NIPBL::NACC1 fusion related). www.pathologyoutlines.com, 2026.
- Yin F. Case of the Quarter (July, 2025), Pancreatobiliary Pathology Society. www.pbpath.org, 2025.
- Akbulut D, Yin F. Chronic granulomatous disease. www.pathologyoutlines.com, 2024.
- Yin F. Case of the Quarter (September, 2024), Pancreatobiliary Pathology Society. www.pbpath.org, 2024.
- Ijaz K, Yin F. Bile duct adenoma. www.pathologyoutlines.com, 2023.
- Perveze I, Yin F. COVID-19 associated colitis. www.pathologyoutlines.com, 2021.
- Zhang T, Yin F. Doxycycline gastropathy. www.pathologyoutlines.com, 2020.
- Sun L, Yin F. IBD associated Colon Tumor. www.pathologyoutlines.com, 2020.
- Yin F, Feely M. Case of the Month, Rodger C. Haggitt Gastrointestinal Pathology Society, 2019.
Other Articles
- Wang L, Zheng W, Liu X, Yin F The Expression of the NF2 Gene as a Novel Prognostic Biomarker for Gastric Adenocarcinoma 104(Supplement 1):S839, 2024.
Editorials
- Yin F, Wang H. Rare Entities and Emerging Issues in Gastrointestinal and Liver Pathology. Journal of Clinical and Translational Pathology 2(3), 2022.
- Yin F, Pan D. Fat flies expanded the hippo pathway: a matter of size control. Sci STKE 2007(380):pe12, 2007. PMID: 17406009.
Abstracts
- Yin F, Yang R, Wang Y, Zheng W, Liu X. Clinicopathological Features of Intrahepatic Cholangiocarcinoma with Enteroblastic Differentiation. USCAP 106(3), 2026. e-Pub 2026.
- Madwani K, Yang R, Zheng W, Liu X, Wang H, Yin F. Histopathological Spectrum of Gastric Adenocarcinoma with RhoA Mutations 106(3, Supplement), 2026. e-Pub 2026.
- Sahin SI, Yin F, Chou E, Zheng W. Aberrant SATB2 Expression in Primary Hepatic and Metastatic Gastric-Derived Hepatoid Carcinomas: A Diagnostic Pitfall 106(3, Supplement):105708, 2026. e-Pub 2026.
- Nazem A, Li X, Yin F, Zhao S, Hou Y, Yang H, Wang Y. Dissecting Image and Language Contributions in Histopathologic Diagnosis: Evaluating Open-Source, Locally Deployable Vision-Language Models MedGemma and QWEN 2.5 106(3, Supplement), 2026. e-Pub 2026.
- Shalaby A, Byrnes K, Mattiolo P, Mohamed A, Du AX, Yin F, Liao X, Balitzer D, Lee H, Luchini C, Adsay NV, Xue Y. Mucinous Cystic Neoplasm of the Extrahepatic Bile Ducts: A Multi-Institutional Case Series 106(3, Supplement), 2026. e-Pub 2026.
- Alvand S, Yin F, Chou E, Haw Y, Zhang L, Deeb K, Farris AB, Krasinskas A, Zheng W. Diagnostic Pitfalls of SATB2-Positive Upper Gastrointestinal Adenocarcinomas: Clinicopathologic and Molecular Characterization 106(3, Supplement), 2026. e-Pub 2026.
- Yang B, Pizzi M, Yang R, Zheng W, Liu X, Cao F, Dhar S, Ajani J, Yin F. Poorly Differentiated Gastric Adenocarcinoma: Clinicopathological and Molecular Profiling of the Subtypes 105(3, Supplement):102955, 2025. e-Pub 2025.
- Sun H, Chou E, Yin F, Farris AB, Saxena R, Krasinskas A, Zheng W. Clinicopathologic and Molecular Analysis of Hepatocellular Carcinoma with Methylthioadenosine Phosphorylase (MTAP) Genomic Loss 105(3, Supplement):103703, 2025. e-Pub 2025.
- Sun H, Yin F, Chou E, Zheng W. Clinicopathologic and Molecular Analysis of Pancreatic Ductal Adenocarcinoma with Methylthioadenosine Phosphorylase Genomic Loss 105(3, Supplement):103861, 2025. e-Pub 2025.
- Cao F, Yin F, Liu X. A Comparative Study of Claudin 18.2 Expression in Sporadic and Inflammatory Bowel Disease-Associated Colorectal Cancer 105(Issue 3, Supplement):102800, 2025. e-Pub 2025.
- Byrnes K, Ballentine S, Dessain A, Kang LI, Ma C, Navale P, Xue Y, Yin F, Zhang D, Ha L, Liu X. Expanding Continuing Pathology Education Beyond One Institution: Utilization of Zoom for Cost-Effective Regional Pathology Case Sharing 105(3, Supplement):102711, 2025. e-Pub 2025.
- Haw Y, Yin F, Zhu F, Sun H, Chou E, Saxena R, Farris AB, Krasinskas A, Zheng W. Clinicopathologic and Molecular Analysis of Hepatocellular Carcinoma with RB1 Mutations/Deletions: A Distinct Non-Chromophobe Subset Featuring Abrupt Anaplasia 105(3, Supplement):103669, 2025. e-Pub 2025.
- Yin F, Liu X. YAP expression in sporadic and inflammatory bowel disease-associated colorectal cancer 487(Suppl 1):S297, 2025. e-Pub 2025.
- Yin F, Wang H, Yang R. SEL1L-NTRK1 is a recurrent gene fusion in pancreatic acinar cell carcinoma with potential therapeutic significance 487(Suppl):S318, 2025. e-Pub 2025.
- Chou E, Xue Y, Sohn A, Zhang L, Yin F, Mo X, Teng Y, (Brad) Farris AB, Krasinskas A, Zheng W. Molecular and Clinicopathologic Analysis of Colorectal Adenocarcinoma with Pancreatobiliary-like Morphology and Immunoprofile 104(Supplement 1):S691, 2024. e-Pub 2024.
- Chou E, Davarpanah A, Yin F, Chen W, Xue Y, Hu J, Teng Y, Zhang L, Kristin, Deeb, Saxena R, (Brad) Farris AB, Krasinskas A, Zheng W. Molecular and Clinicopathologic Analysis of Hepatocellular Carcinoma with Homologous Recombination Deficiency 104(Supplement 1):S1651, 2024. e-Pub 2024.
- Chou E, Yin F, Sohn A, Zhang L, Zheng W. Molecular and Clinicopathologic Analysis of Gastroesophageal Carcinoma with Paneth Cell-Like Features 104(Supplement 1):S692, 2024. e-Pub 2024.
- Wang L, Zheng W, Liu X, Yin F. Molecular Profiling of Colonic Mucinous Carcinoma with Signet Ring Cell Features 104(Supplement 1):S840, 2024. e-Pub 2024.
- Sohn AJ, Yin F, Teng Y, Zhang L, Deeb KK, Zheng W. Clinicopathologic and Molecular Analysis of Gastric Carcinoma With Homologous Recombination Deficiency 103(Supplement):S636, 2023. e-Pub 2023.
- Wang L, Liu X, Yin F. Distinct Clinicopathologic and Molecular Subgroups in Colorectal Adenocarcinoma 103(Supplement):S641, 2023. e-Pub 2023.
- Chou E, Yin F, Teng Y, Yu MA, Zhang L, Lai J, Zheng W. Hepatocellular Carcinoma with Foamy Histiocyte-Like Features: A Contemporary Clinicopathologic Analysis of Five Cases with Molecular Profile Study 103(Supplement):S1350, 2023. e-Pub 2023.
- Chou E, Hsiao WY, Yin F, Teng Y, Zhang L, Farris AB, Sexena R, Krasinaskas AM, Zheng W. Molecular and Clinicopathologic Analysis of Hepatocellular Carcinomas With Aberrant CDX2, SATB2, CK20 and CK19 Expression 103(Supplement):S1351, 2023. e-Pub 2023.
- Agulto, A, Bukeirat F, Veysel T, Chela HK, Yin F. An Uncommon Cause for Common Symptoms of Abdominal Pain and Diarrhea: A Case Report of Human Intestinal Spirochetosis in an Immune-Competent Patient 117(10S):e1510, 2022. e-Pub 2022.
- Reznicek, E, Pasha SB, Ertugrul H, Veysel T, Daglilar E, Yin F. Monoclonal Immunoglobulin Deposition Disease: A Rare Case of Acute Liver Failure 117(10S):e1989, 2022. e-Pub 2022.
- Fard, D, Mansour M, Chela HK, Al Juboori A, Yin F, Hammoud G. Gastric Spindle Cell Leiomyosarcoma Is Associated With Chronic Helicobacter pylori Infection 117(10S):e2267, 2022. e-Pub 2022.
- Wang L, Liu X, Yin F. Somatic Mutations in FAT Cadherin Family Members Constitute an Underrecognized Subtype of Colorectal Adenocarcinoma with Favorable Clinicopathologic Features 35(suppl 2):539, 2022. e-Pub 2022.
- Chela HK, Mikhael M, Basar O, Yin F, Tahan V, Daglilar E. A Rare Cause of Dysphagia: Polypoidal Esophageal Masses From Poorly Differentiated Thymic Cancer 116:S926-S927, 2021. e-Pub 2021.
- Arshi J, Yin F. Xanthogranulomatous Inflammation of The Uterus Presenting as A Mass Lesion: A Rare Case Report 145(9s1):e73, 2021. e-Pub 2021.
- Chela HK, Mikhael M, Basar O, Yin F, Tahan V, Daglilar E. Esophagitis Dissecans Superficialis Associated With Lymphoma 116:S927, 2021. e-Pub 2021.
- Turner C, Rao D, Yin F. Gastric Amyloidosis Presenting as Gastrointestinal Bleeding: Case Report and Concise Review 145(9s1):e3, 2021. e-Pub 2021.
- Arshi J, Yin F. Normal Duodenal Histology in Cases with Abnormal Celiac Serology: Dilemma in Gastroenterology Practices 34(suppl 2):385, 2021. e-Pub 2021.
- Chela HK, Mikhael M, Basar O, Yin F, Tahan V, Daglilar E. A Rare Case of Ectopic Pancreas Spotted as a Small Nodularity in Distal Esophagus 116:S709-S710, 2021. e-Pub 2021.
- Arshi J, Nguyen J, Yin F. Russell Body Esophagitis with Gastritis: A Rare Case Report 144(9s1):e15, 2020. e-Pub 2020.
- Sun L, Arshi J, Yin F. A 3-Case Report Study of Esophageal Hyperplastic Polyp: Clinicopathologic Findings and Literature Review 144(9s1):e22, 2020. e-Pub 2020.
- Perveze I, Lu A, Rao D, Yin F. Human Papillomavirus–Related Anorectal Adenocarcinoma 144(9s1):e32, 2020. e-Pub 2020.
- Yin F, Xie H, Lai J, Dong J, Liu X. Double Negative for Expression of YAP1 and CDX2 Defines a Subgroup of Colitis-Associated Colorectal Cancer with Early Onset and Aggressive Features 100(SUPPL 1):807-809, 2020. e-Pub 2020.
- Yin F, Wang K, Starostik P, Newsom KJ, Feely M, Liu X. Deleterious mutations in esophageal carcinoma cuniculatum detected by next generation sequencing 100(SUPPL 1):809-810, 2020. e-Pub 2020.
- Sun L, Nguyen J, Yin F. Correlation between the Tumor budding and Tumor Microenvironment in Pancreatic ductal adenocarcinoma 100(SUPPL 1):1678, 2020. e-Pub 2020.
- Sun L, Nguyen J, Yin F, Rao D. A six-case review of granular cell tumor in a rare location (colon) of the gastrointestinal tract 144(9s1):e36, 2020. e-Pub 2020.
- Sun L, Allison D, Yin F. Russell Body Duodenitis in A Patient with Duodenal Adenoma and High-Grade Dysplasia 154(Supplement_1):S75, 2020. e-Pub 2020.
- Tarar ZI, Tahan V, Daglilar E, Basar O, Yin F. A Rare Case of Hyperplastic Polyp of Esophagus on a Schatzki’s Ring 115:S1008, 2020. e-Pub 2020.
- Mubarak M, Chowdhury NR, Yin F, Das K. Doxycycline-Induced Gastric Mucosal Injury: A Rare Diagnosis 115:S1603-S1604, 2020. e-Pub 2020.
- Yin F, Saad M, Lin J, Jackson CR, Ren B, Lawson C, Karamchandani DM, Bernabeu BQ, Dhir T, Zheng R, Schultz CW, Jiang W, Zhang D, Thomas CL, Zhang X, Lai J, Liu X. Splenic arterial involvement is associated with poor prognosis in resected distal pancreatic cancer 32(suppl 2):55, 2019. e-Pub 2019.
- Akki AS, Sanchez D, Yin F, Lai J, Liu X, Esnakula AK. Challenges in interpreting early Barrett adenocarcinoma in endoscopic submucosal dissection specimens 32(suppl 2):3, 2019. e-Pub 2019.
- Lai J, Chamala S, Yin F, Cameron ME, Liu X, Starostik P, Trevino JG. Identification of racial-specific novel mutations in pancreatic ductal adenocarcinoma by whole-exome sequencing: comparison of African American patients to Caucasian patients 32(suppl 2):20, 2019. e-Pub 2019.
- Saad M, Yin F, Lin J, Jackson CR, Ren B, Lawson C, Karamchandani DM, Bernabeu BQ, Dhir T, Zheng R, Schultz CW, Jiang W, Zhang D, Thomas CL, Zhang X, Lai J, Liu X. Comparison and Validation of AJCC 7th and 8th Editions of TNM Staging in Resectable Distal Pancreatic Cancer 32(suppl 2):46, 2019. e-Pub 2019.
- Yin F, Fu DA, Akki AS, Esnakula AK, Feely M, Hernandez Gonzalo D, Kresak JL, Lai J, Liu X. Yes-Associated Protein 1 (YAP1) is a Novel Progressive Marker for Early Stage Esophageal Adenocarcinoma 32(suppl 2):148, 2019. e-Pub 2019.
- Zheng W, Cheng L, Yin F, Fung KM, Osunkoya AO. Vascular Tumors of the Adrenal Gland: A Multi-institutional Clinicopathologic Analysis of 27 Cases 31(suppl 2):402, 2018. e-Pub 2018.
- Yin F, Zheng W, Lucas MD, Allen RA, Zhou Y. Reduction of BCR-ABL ordering errors through multipronged quality improvement interventions 31(suppl 2):798, 2018. e-Pub 2018.
- Yin F, Sughrue ME, Vinters HV, Tashjian R, Fung KM. Hypertrophic hyalinizing vasculopathy presenting as a cerebellar mass 139(10):e110-e111, 2015. e-Pub 2015.
- Gowani F, Deel C, Lowery P, Barton L, Tran N, Yin F, Akl P, Blick K. An Evaluation of the HemoCue Assay for the Rapid Assessment of Plasma Free Hemoglobin (PfHb) in Pediatric Patients Undergoing Extracorporeal Membrane Oxygenation (ECMO) 61(Supplement):S183, 2015. e-Pub 2015.
Book Chapters
- Yin F, Liu X. Alpha1 Antitrypsin Deficiency-Associated Liver Injury. In: Practical Interpretation of Liver Biopsy. 1st. Cambridge Scholars Publishing, 900 pages, 2020.
Patient Reviews
CV information above last modified September 03, 2026