Francesca Cole, Ph.D.
Department of Epigenetics and Molecular Carcinogenesis, Division of Discovery Science
Present Title & Affiliation
Primary Appointment
Professor, Department of Epigenetics and Molecular Carcinogenesis, Division of Division of Discovery Science, UT MD Anderson
Associate Dean of Academic Affairs (MDACC), University of Texas MD Anderson UTHealth Houston Graduate School of Biomedical Sciences, Houston, Texas
Director of Trainee Transitions, Epigenetics and Molecular Carcinogenesis, The University of Texas MD Anderson Cancer Center, Houston, TX
Associate Professor, Epigenetics and Molecular Carcinogenesis, The University of Texas MD Anderson Cancer Center, Houston, TX
Dual/Joint/Adjunct Appointment
Professor, Epigenetics and Molecular Carcinogenesis, The University of Texas MD Anderson Cancer Center, Houston, Texas
Associate Dean of Academic Affairs (MDACC), University of Texas MD Anderson UTHealth Houston Graduate School of Biomedical Sciences, Houston, Texas
Director of Trainee Transitions, Epigenetics and Molecular Carcinogenesis, The University of Texas MD Anderson Cancer Center, Houston, TX
Research Interests
Compromised DNA repair is a common feature of cancers and contributes to loss of genome integrity and tumorigenesis. A critical mechanism to faithfully repair DNA lesions, especially double-strand breaks, is homologous recombination. While many homologous recombination pathway components have been identified, their in vivo roles, especially within mammalian genomic contexts are poorly understood. Research in my laboratory uses genetic and molecular techniques to determine how homologous recombination pathways collaborate, compete, and compensate for one another. In particular, we use newly developed assay systems that take advantage of meiotic recombination in mouse spermatocytes to comprehensively dissect at high-resolution recombination outcomes. We plan to leverage this approach to (1) define the in vivo molecular characteristics of independent DNA repair pathways (2) discover new components of these pathways (3) provide a means of testing chemotherapeutic agents to specifically perturb individual pathways with a hope to improve cancer therapies.
Education & Training
Degree-Granting Education
| 2003 | Mount Sinai School of Medicine of New York University, New York, New York, US, Biomedical Sciences, Ph.D |
| 1992 | Hunter College of the City University of New York, New York, New York, US, Biological Sciences, BA |
Postgraduate Training
| 2004-2012 | Research Fellowship, Memorial Sloan-Kettering Cancer Center, New York, New York |
| 2003-2004 | Research Fellowship, Mount Sinai School of Medicine, New York, New York |
Experience & Service
Faculty Academic Appointments
Associate Professor, Epigenetics and Molecular Carcinogenesis, The University of Texas MD Anderson Cancer Center, Houston, TX, 2018 - 2025
Assistant Professor, Epigenetics and Molecular Carcinogenesis, The University of Texas MD Anderson Cancer Center, Smithville, TX, 2012 - 2018
Administrative Appointments/Responsibilities
Liason- Research Program (RP)-Cancer Research Training & Education Coordination (CRTEC), The University of Texas MD Anderson Cancer Center, Houston, Texas, 2025 - Present
GSBS Faculty Vice President and President Elect, University of Texas MD Anderson Cancer Center UTHealth Houston Graduate School of Biomedical Sciences, Houston, TX, 2024 - 2025
Co-Director The Academy at GSBS, University of Texas MD Anderson Cancer Center UTHealth Houston Graduate School of Biomedical Sciences, Houston, Texas, 2024 - Present
Program Director (Genetics and Epigenetics program), UT MD Anderson UTHealth Houston Graduate School of Biomedical Sciences, Houston, TX, 2022 - 2024
Program Co-Director (Genetics and Epigenetics program), UT MD Anderson UTHealth Houston Graduate School of Biomedical Sciences, Houston, TX, 2020 - 2022
Intramural Institutional Committee Activities
Member, Education Subcommittee for Faculty Senate, The University of Texas MD Anderson Cancer Center, 2024 - Present
Extramural Institutional Committee Activities
Liason, Cancer Research Training and Education Committee Liaison, The University of Texas MD Anderson Cancer Center, 2025 - Present
Member, Technology Task Force Committee, The University of Texas MD Anderson Cancer Center, 2024 - 2027
Past Chair, MD Anderson Graduate Education Committee, The University of Texas MD Anderson Cancer Center, 2024 - 2025
Chair, GSBS Executive Committee, The University of Texas MD Anderson Cancer Center, 2024 - 2025
Member, Research Investigation Committee DIO 7735, The University of Texas MD Anderson Cancer Center, 2023 - Present
Member, Advisory committee for EMC chair search, The University of Texas MD Anderson Cancer Center, 2023 - Present
Chair, MD Anderson Graduate Education Committee, The University of Texas MD Anderson Cancer Center, 2023 - 2024
Member, Research Investigation Committee DIO 7736, The University of Texas MD Anderson Cancer Center, 2023 - 2023
Member, Research Integrity Matters DIO 7735/7736 Inquiry Committee, The University of Texas MD Anderson Cancer Center, 2023 - 2023
Vice Chair, MD Anderson Graduate Education Committee, The University of Texas MD Anderson Cancer Center, 2022 - 2023
Member, Advisory committee for Postdoctoral Affairs, The University of Texas MD Anderson Cancer Center, 2022 - Present
Member, Advisory committee for the GSBS Core Course, The University of Texas MD Anderson Cancer Center, 2022 - Present
Chair, GEC Social Media subcommittee, The University of Texas MD Anderson Cancer Center, 2021 - 2022
Member, Smithville Move - Space Committee, The University of Texas MD Anderson Cancer Center, 2021 - 2022
Member, Program Income Advisory Committee for the CCSG Research Animal Support Facility, The University of Texas MD Anderson Cancer Center, 2021 - Present
Member, Cancer Medicine Division Head Search Committee, The University of Texas MD Anderson Cancer Center, 2021 - 2023
Member, Scientific Review Panel for MDACC cluster faculty recruitment, The University of Texas MD Anderson Cancer Center, 2021 - 2022
Member, Postdoctoral Office Director Search Committee, The University of Texas MD Anderson Cancer Center, 2021 - 2022
Chair, GEC Covid-19 Environment Subcommittee, The University of Texas MD Anderson Cancer Center, 2020 - 2021
Chair, GEC Professionalism Subcommittee, The University of Texas MD Anderson Cancer Center, 2020 - 2021
Member, Advisory committee for South Campus animal facility, The University of Texas MD Anderson Cancer Center, 2020 - Present
Member, EMC Travel Award Committee, The University of Texas MD Anderson Cancer Center, 2020 - Present
Member, Academic Review Committee, The University of Texas MD Anderson Cancer Center, 2020 - 2023
Member, GSBS Admissions Committee, The University of Texas MD Anderson Cancer Center, 2020 - 2022
At-Large Member, Scientists for Basic/Laboratory Research Restart Planning Committee, The University of Texas MD Anderson Cancer Center, 2020 - 2021
Reviewer, Moon Shots Program, The Disruptive Science Grant - Review Committee, The University of Texas MD Anderson Cancer Center, 2020
Reviewer, INTEREST study section, The University of Texas MD Anderson Cancer Center, 2020
Member, Graduate Education Committee, The University of Texas MD Anderson Cancer Center, 2019 - Present
Member, Smithville Move - Animal Transfers Committee, The University of Texas MD Anderson Cancer Center, 2019 - Present
Member, Flow Cytometry and Cell Imaging Core (FCCIC) Oversight Committee, The University of Texas MD Anderson Cancer Center, 2019 - Present
Member, Genetics and Epigenetics Steering Committee, The University of Texas MD Anderson Cancer Center, 2018 - Present
Member, Faculty Search Committee for Immunology Open Rank, The University of Texas MD Anderson Cancer Center, 2018 - 2022
Member, Committee for MD Anderson Cancer Center’s 2018 Alfred G. Knudson, Jr., Award, The University of Texas MD Anderson Cancer Center, 2018
Member, CPRIT High-Impact/High Risk (HIHR) LOI Review Committee, The University of Texas MD Anderson Cancer Center, 2018
Member, Genetics and Epigenetics Curriculum Committee, The University of Texas MD Anderson Cancer Center, 2017 - 2018
Member, Faculty Search Committee for Epigenetics and Molecular Carcinogenesis - Professor, The University of Texas MD Anderson Cancer Center, 2016 - 2017
Member, GSBS Epigenetics and Molecular Carcinogenesis Program and Genes and Development Program Merger Committee, Curriculum Committee, The University of Texas MD Anderson Cancer Center, 2016 - 2017
Member, GSBS Epigenetics and Molecular Carcinogenesis Program and Genes and Development Program Merger Committee, Community Committee, The University of Texas MD Anderson Cancer Center, 2016 - 2017
Member, Animal Resource Facility Advisory Committee (Science Park), The University of Texas MD Anderson Cancer Center, 2016 - 2021
Member, Epigenetics and Molecular Carcinogenesis Admissions Committee, The University of Texas MD Anderson Cancer Center, 2016 - 2018
Member, Faculty Search Committee for Epigenetics and Molecular Carcinogenesis Bioinformatician, The University of Texas MD Anderson Cancer Center, 2016 - 2017
Member, Faculty Academic Review Committee (FARC), The University of Texas MD Anderson Cancer Center, 2015 - Present
Member, Epigenetics and Molecular Carcinogenesis Admissions Committee, The University of Texas MD Anderson Cancer Center, 2015 - 2016
Member, CPRIT High-Impact/High Risk (HIHR) LOI Review committee, The University of Texas MD Anderson Cancer Center, 2015
Member, GSBS Academic Standards Committee, The University of Texas MD Anderson Cancer Center, 2014 - 2017
Member, Odyssey Program Advisory Committee, The University of Texas MD Anderson Cancer Center, 2014 - 2017
Member, Epigenetics and Molecular Carcinogenesis and Genes and Development Joint Retreat Committee, The University of Texas MD Anderson Cancer Center, 2014 - 2015
Member, Steering Committee, Program in Epigenetics and Molecular Carcinogenesis, The University of Texas MD Anderson Cancer Center, 2013 - 2016
Member, Molecular Carcinogenesis Admissions Committee, Member, The University of Texas MD Anderson Cancer Center, 2013 - 2014
Member, Faculty Search Committee for Epigenetics and Molecular Carcinogenesis Assistant Professor, The University of Texas MD Anderson Cancer Center, 2013 - 2014
Member, Molecular Carcinogenesis and Genes and Development Joint Retreat Committee, The University of Texas MD Anderson Cancer Center, 2013 - 2014
Member, Faculty Search Committee for Molecular Carcinogenesis Assistant Professor, The University of Texas MD Anderson Cancer Center, 2012 - 2013
Reviewer, Roquemore Scholarship in Cancer Research, The University of Texas MD Anderson Cancer Center, 2012
Reviewer, American Legion Auxiliary Fellowship, The University of Texas MD Anderson Cancer Center, 2012
Editorial Activities
Editorial committee, Annual Review of Genetics, 2024 - 2028
Series Editor, Current Topics in Developmental Biology, 2021 - Present
Advisor to Editor, Current Biology, 2020 - Present
Guest Editor, Annual Review of Genetics, 2020
Associate Editor for the Genome Integrity and Transmission section, Genetics, 2019 - Present
Editor of special issue, Chromosoma, 2018 - Present
Advisor to Editor, BMC Biology, 2018 - Present
Honors & Awards
| 2025 - Present | TAMEST Protégé |
| 2024 | President's Recognition of Faculty Excellence in Education and Mentorship Advancement, UT MD Anderson Cancer Center |
| 2023 | President's Recognition of Faculty Excellence in Education and Mentorship Advancement, The University of Texas MD Anderson Cancer Center |
| 2022 - Present | Reappointed with Commendation for service to the GSBS Graduate School of Biomedical Sciences, GSBS Graduate School of Biomedical Sciences |
| 2022 | D. Dudley and Judy White Oldham Faculty Award, Graduate School of Biomedical Sciences |
| 2021 - 2023 | Andrew Sabin Family Foundation Fellowship, The University of Texas MD Anderson Cancer Center |
| 2020 | Alfred G. Knudson, Jr., Outstanding Dissertation Award (Mentor), GSBS |
| 2018 | Wall of Science Awardee, University of Texas MD Anderson Cancer Center |
| 2018 | President's Recognition of Faculty Excellence in Research, The University of Texas MD Anderson Cancer Center |
| 2017 | Reappointed with Commendation for service to the GSBS, Graduate School of Biomedical Sciences |
| 2015 - 2020 | NIH Director's New Innovator awardee, NIH Common Fund |
| 2014 - 2016 | R. Lee Clark Fellow, The University of Texas MD Anderson Cancer Center |
| 2012 - 2016 | CPRIT Scholar in Cancer Research, Cancer Prevention and Research Institute of Texas |
| 2007 | Support for young participants Award, 8th European Meiosis Meeting, Kanagawa, Japan |
| 2006 - 2009 | Ruth L. Kirschstein National Research Service Award Individual Fellowship, NIH |
| 2006 | American Cancer Society Postdoctoral Fellowship Award (declined), American Cancer Society |
| 2000 - 2002 | Predoctoral Training Grant Fellow, Training in Cancer Biology, NIH |
| 1997 - 1999 | Predoctoral Fellow, Howard Hughes Medical Institute |
| 1992 - 1995 | Predoctoral Fellow, Howard Hughes Medical Institute |
| 1992 | David L. Klein Jr. Memorial Scholarship |
| 1992 | Honorable Mention, Graduate Fellowship, National Science Foundation |
| 1992 | Phi Beta Kappa |
| 1992 | Sigma Xi |
| 1992 | Theodora (Teddy) Salmon Award for Excellence in Research in the Biological Sciences |
| 1990 | Sigma Xi Summer Research Fellowship |
Professional Memberships
Selected Presentations & Talks
Formal Peers
- 2025. Age-dependent alterations in recombination compromises sperm quality. Invited. New York, NY, US.
- 2023. Age-dependent alterations in recombination cause aneuploidies in mouse spermatocytes. Invited. Houston, TX, US.
- 2023. Age-dependent alterations in recombination cause aneuploidies in mouse spermatocytes. Invited. Kansas City, MO, US.
- 2023. Age-dependent alterations in recombination cause aneuploidies in mouse spermatocytes. Invited. Kansas City, MO, US.
- 2023. Age-dependent alterations in recombination cause aneuploidies in mouse spermatocytes. Invited. Cologne, DE.
- 2023. Genetic dissection of crossover mutants reveals novel features of crossover precursors. Invited. Valhalla, US.
- 2022. Aged mouse spermatocytes lose crossover homeostasis. Invited. Houston, TX, US.
- 2022. Ensuring crossovers in mammalian meiosis. Invited. Chapel Hill, NC, US.
- 2021. How DNA repair by homologous recombination ensures accurate chromosome segregation into sperm (Zoom Presentation). Invited. Houston, TX, US.
- 2021. How chromosome structure and recombination ensure segregation into sperm (Zoom Presentation). Invited. Ann Arbor, MI, US.
- 2021. How chromosomes segregate into gametes – the mammalian edition (Virtual Seminar). Invited. Iowa City, IA, US.
- 2020. How chromosomes segregate into gametes – the mammalian edition (Virtual seminar). Invited. Newark, DE, US.
- 2020. How DNA repair by homologous recombination ensures segregation into sperm (Zoom Presentation). Invited. New York, NY, US.
- 2020. How age-dependent alterations of chromosome structure and recombination lead to mis-segregation in sperm (Zoom Presentation). Invited. Copenhagen, DK.
- 2020. How chromosome structure and recombination ensure homolog segregation into sperm (Zoom Presentation). Invited. Urbana, IL, US.
- 2020. How chromosome structure and recombination ensure homolog segregation in mammalian meiosis (Zoom Presentation). Invited. Baltimore, MD, US.
- 2020. How chromosome structure and recombination ensure homolog segregation in mammalian meiosis (Virtual Seminar). Invited. Kansas City, MO, US.
- 2020. How chromosome structure and recombination ensure homolog segregation in mammalian meiosis (postponed due to Coronavirus travel restrictions). Invited. Cologne, DE.
- 2020. How chromosome structure and recombination ensure homolog segregation in mammalian meiosis (Zoom Presentation). Invited. Washington, DC, US.
- 2020. Recombination pathway choice in mouse spermatocytes. Invited. Baltimore, MD, US.
- 2020. How chromosome structure and recombination ensure homolog segregation in meiosis (Postponed due to coronavirus travel restrictions). Invited. Newark, DE, US.
- 2020. How chromosome structure and recombination ensure homolog segregation in mammalian meiosis. Invited. Ithaca, NY, US.
- 2019. Meiotic recombination mechanisms in mammals. Invited. New York, NY, US.
- 2019. Meiosis and chromosome segregation in mammals: why younger isn’t always better. Invited. San Antonio, TX, US.
- 2019. How chromosome structure and recombination ensure homolog segregation in meiosis. Invited. Austin, TX, US.
- 2019. Meiosis and chromosome segregation. Invited. Eugene, OR, US.
- 2019. DNA repair by homologous recombination, lessons from mammalian meiosis. Invited. San Antonio, TX, US.
- 2019. Keynote speaker for the 2nd Annual Lab Coat Ceremony. Invited. New York, NY, US.
- 2019. How chromosome structure and recombination ensure homolog pairing and segregation in mouse spermatocytes. Invited. Besthesda, MD, US.
- 2019. Meiosis and chromosome segregation in mammals: why younger isn’t always better. Invited. Ann Arbor, MI, US.
- 2018. Meiosis and chromosome segregation in mammals: why younger isn’t always better. Invited. Philadelphia, PA, US.
- 2018. Meiotic recombination mechanisms in mammals. Invited. New York, NY, US.
- 2018. Temporal, spatial, and genetic regulation of meiotic recombination in mouse spermatocytes. Invited. Cambridge, GB.
- 2018. Timing is everything: Meiotic recombination mechanisms in mammals. Invited. Houston, TX, US.
- 2018. Meiosis and chromosome segregation in mammals: why younger isn’t always better. Invited. San Antonio, TX, US.
- 2018. Meiosis and chromosome segregation in mammals: why younger isn’t always better. Invited. Houston, TX, US.
- 2017. Temporal, spatial, and genetic differentiation of meiotic recombination pathways. Invited. Davis, CA, US.
- 2017. Temporal, spatial, and genetic distinctions between meiotic recombination pathways. Invited. Houston, TX, US.
- 2017. Timing is everything: Meiotic recombination mechanisms in mammals. Invited. Santa Cruz, CA, US.
- 2017. Meiosis and chromosome segregation in mammals: why younger isn’t always better. Invited. Palo Alto, CA, US.
- 2017. Chromosome mis-segregation in spermatocytes and the paternal age effect: 15 is the new 40. Invited. Montpellier, FR.
- 2017. Regulation of meiotic recombination in mouse. Invited. Madison, WI, US.
- 2017. Many are called, but few are chosen: Regulation of meiotic recombination in mammals. Invited. Bloomington, IN, US.
- 2016. Regulation of meiotic recombination in mouse. Invited. Chicago, IL, US.
- 2016. A meiopic view of recombination. Invited. Houston, TX, US.
- 2015. Active suppression of mitotic homologous recombination pathways promote crossover control in meiosis. Invited. Ithaca, NY, US.
- 2014. Meiotic recombination mechanisms and hotspot evolutionary dynamics revealed by mouse tetrad analysis. Invited. Los Angeles, CA, US.
- 2014. Meiotic recombination mechanisms and hotspot evolutionary dynamics revealed by mouse tetrad analysis. Invited. Austin, TX, US.
- 2014. Preaching about the converted: Recombination mechanisms in mouse meiosis. Invited. Houston, TX, US.
- 2014. Homologous recombination in mouse meiosis. Invited. Houston, TX, US.
- 2014. Preaching about the converted: Recombination mechanisms and hotspot evolutionary dynamics in mouse meiosis. Invited. Davis, CA, US.
- 2013. Preaching about the converted: Homologous recombination mechanisms in mouse meiosis. Invited. Houston, TX, US.
- 2012. Homologous recombination mechanisms in mouse meiosis. Invited. Ithaca, NY, US.
- 2011. Homologous recombination mechanisms in mouse meiosis. Invited. Smithville, TX, US.
- 2011. Dissecting homologous recombination mechanisms in mouse meiosis. Invited. Oxford, GB.
- 2011. Meiotic recombination in mammalian spermatogenesis. Invited. Pittsburgh, PA, US.
- 2011. Dissecting recombination mechanisms in mammalian meiosis. Invited. Smithville, TX, US.
- 2010. Distinguishing homologous recombination pathways in mammalian meiosis. Invited. Bethesda, MD, US.
- 2010. Crossover and noncrossover differentiation in mouse meiotic recombination. Invited. Oklahoma City, OK, US.
- 2007. Crossover regulation in mammalian meiotic recombination. Invited. Norfolk, VA, US.
- 2005. Positive regulation of myogenic bHLH factors and skeletal muscle development by the cell surface receptor CDO. Invited. New York, NY, US.
Grant & Contract Support
| Date: | 2025 - 2026 |
| Title: | Reconciling DNA repair by homologous recombination and interhomolog pairing in meiosis |
| Funding Source: | Bridge Funding, UTMDACC |
| Role: | PI |
| ID: | RCTS 2026-00065750-Y1 |
| Date: | 2023 - 2027 |
| Title: | The Role of ZCWPW1 in Meiosis |
| Funding Source: | NIH/NIGMS |
| Role: | MPI |
| ID: | R01GM148028 |
Selected Publications
Peer-Reviewed Articles
- Previato De Almeida L, Premkumar T, Kawecka MK, Gryniuk I, Carbajal A, Cole F, Pezza R. RMI2 regulates recombination intermediate metabolism to ensure proper chromosome segregation in mammalian meiosis. Nucleic Acids Res. e-Pub 2026.
- Xie W, Gowder M, Bazzano D, Shami AN, Pandey A, Frasca M, Paniker L, de Almeida LP, Bharati BK, Liang J, Toth A, DeSantis M, Nandakumar J, Nudler E, Mosalaganti S, Pezza R, Cole F, Hammoud SS. ZCWPW1 organizes telomeric architecture to drive meiotic chromosome movements. bioRxiv, 2026. e-Pub 2026. PMID: 41676639.
- Frasca M, Paniker L, Kang R, Chakraborty P, Pandey A, LoPresti J, Cole F. MutSgamma promotes meiotic recombination and homolog pairing in mouse spermatocytes. Genetics 230(3), 2025. e-Pub 2025. PMID: 40404295.
- Premkumar T, Paniker L, Kang R, Biot M, Humphrey E, Destain H, Ferranti I, Okulate I, Nguyen H, Kilaru V, Frasca M, Chakraborty P, Cole F. Genetic dissection of crossover mutants defines discrete intermediates in mouse meiosis. Mol Cell 83(16):2022.08.10.503530, 2023. e-Pub 2023. PMID: 37595556.
- Cole F. Preface. Curr Top Dev Biol 151:xv-xviii, 2023. e-Pub 2023. PMID: 36681480.
- Billmyre KK, Bravo Núñez MA, Bishop DK, Cole F. Meiosis in Quarantine discussions lead to an action plan to increase diversity and inclusion within the genetics community. PLoS Genet 17(7):e1009648, 2021. e-Pub 2021. PMID: 34264967.
- Toraason E, Horacek A, Clark C, Glover ML, Adler VL, Premkumar T, Salagean A, Cole F, Libuda DE. Meiotic DNA break repair can utilize homolog-independent chromatid templates in C. elegans. Curr Biol 31(7):1508-1514.e5, 2021. e-Pub 2021. PMID: 33740427.
- Cole F, Borde V. Special issue on "recent advances in meiosis from DNA replication to chromosome segregation". Chromosoma 128(3):177-180, 2019. e-Pub 2019. PMID: 31616989.
- Patel L, Kang R, Rosenberg SC, Qiu Y, Raviram R, Chee S, Hu R, Ren B, Cole F, Corbett KD. Dynamic Reorganization of the Genome Shapes the Recombination Landscape in Meiotic Prophase. Nat Struct Mol Biol 26(3):164-174, 2019. e-Pub 2019. PMID: 30778236.
- Barsh GS, Bhalla N, Cole F, Copenhaver GP, Lacefield S, Libuda DE. 2018 PLOS Genetics Research Prize: Bundling, stabilizing, organizing-The orchestration of acentriolar spindle assembly by microtubule motor proteins. PLoS Genet 14(9):e1007649, 2018. e-Pub 2018. PMID: 30212501.
- Kang R, Zelazowski MJ, Cole F. Missing the mark: PRDM9-dependent methylation is required for meiotic DSB targeting. Mol Cell 69(5):725-727, 2018. e-Pub 2018. PMID: 29499130.
- Zelazowski MJ, Sandoval M, Paniker L, Hamilton HM, Han J, Gribbell MA, Kang R, Cole F. Age-dependent alterations in meiotic recombination cause chromosome segregation errors in spermatocytes. Cell 171(3):601-614.e13, 2017. e-Pub 2017. PMID: 28942922.
- Takata KI, Reh S, Yousefzadeh MJ, Zelazowski MJ, Bhetawal S, Trono D, Lowery MG, Sandoval M, Takata Y, Lu Y, Lin K, Shen J, Kusewitt DF, McBride KM, Cole F, Wood RD. Analysis of DNA polymerase ν function in meiotic recombination, immunoglobulin class-switching, and DNA damage tolerance. PLoS Genet 13(6):e1006818, 2017. e-Pub 2017. PMID: 28570559.
- Hansen RK, Mund A, Poulsen SL, Sandoval M, Klement K, Tsouroula K, Tollenaere MA, Räschle M, Soria R, Offermanns S, Worzfeld T, Grosse R, Brandt DT, Rozell B, Mann M, Cole F, Soutoglou E, Goodarzi AA, Daniel JA, Mailand N, Bekker-Jensen S. SCAI promotes DNA double-strand break repair in distinct chromosomal contexts. Nat Cell Biol 18(12):1357-1366, 2016. e-Pub 2016. PMID: 27820601.
- Vélez-Cruz R, Manickavinayaham S, Biswas AK, Clary RW, Premkumar T, Cole F, Johnson DG. RB localizes to DNA double-strand breaks and promotes DNA end resection and homologous recombination through the recruitment of BRG1. Genes Dev 30(22):2500-2512, 2016. e-Pub 2016. PMID: 27940962.
- Li M, Cole F, Patel DS, Misenko SM, Her J, Malhowski A, Alhamza A, Zheng H, Baer R, Ludwig T, Jasin M, Nussenzweig A, Serrano L, Bunting SF. 53BP1 Ablation Rescues Genomic Instability In Mice Expressing 'RING-less' BRCA1. EMBO Rep 17(11):1532-1541, 2016. e-Pub 2016. PMID: 27670884.
Invited Articles
- Humphrey E, Cole F. How sex chromosomes break up to get together. Nature 582(7812):346-347, 2020. e-Pub 2020. PMID: 32541910.
- Zelazowski MJ, Cole F. X marks the spot: PRDM9 rescues hybrid sterility by finding hidden treasure in the genome. Nat Struct Mol Biol 23(4):267-9, 2016. e-Pub 2016. PMID: 27045445.
Other Articles
- Kang, JS, Yi, MJ, Zhang, W, Feinleib, JL, Cole Bergemann, F, Krauss, RS Correction to. Journal of Cell Biology 222(10), 2023. PMID: 37702713.
Books (edited and written)
- Cole F. Meiosis in Development and Disease, 2023.
Patient Reviews
CV information above last modified September 15, 2026