Gabriel M. Pagnotti, Ph.D.
Department of Endocrine Neoplasia and Hormonal Disorders, Division of Internal Medicine
Present Title & Affiliation
Primary Appointment
Associate Director, Bone Disease Program of Texas, The University of Texas MD Anderson Cancer Center, Houston, Texas
Associate Member, Graduate School of Biomedical Sciences, The University of Texas MD Anderson Cancer Center, Houston, Texas
Assistant Professor, Endocrine Neoplasia and Hormonal Disorders - Research, The University of Texas MD Anderson Cancer Center, Houston, TX
Dual/Joint/Adjunct Appointment
Assistant Professor, Endocrine Neoplasia and Hormonal Disorders - Research, The University of Texas MD Anderson Cancer Center, Houston, TX
Education & Training
Degree-Granting Education
| 2014 | SUNY Stony Brook University, Stony Brook, New York, US, Ph.D. in Biomedical Engineering |
| 2008 | University of South Florida, Tampa, Florida, US, M.S. in Biomedical Engineering |
| 2002 | University of Central Florida, Orlando, Florida, US, B.S. in Electrical Engineering |
Postgraduate Training
| 2016-2020 | Postgraduate Fellow, Endocrine/Hematology, Indiana University, Indianapolis, Indiana |
| 2014-2016 | Postdoctoral Associate, Biomedical Engineering, SUNY Stony Brook University, Stony Brook, New York |
| 2003-2005 | Post-Baccalaureate Studies, Molecular & Microbiology, University of Central Florida, Orlando, FL |
Licenses & Certifications
| null | Fundamental of the Bioscience Industry |
Experience & Service
Other Professional Positions
Maintenance and Oversight of Micro-Computed Tomography Equipment, The University of Texas MD Anderson Cancer Center, Houston, Texas, 2020 - Present
Graduate Teaching Assistant, Introduction to Genetic Engineering, Stony Brook University, Stony Brook, NY, 2009 - 2010
Graduate Teaching Assistant, Introduction to Biomedical Engineering, Stony Brook University, Stony Brook, NY, 2009 - 2010
Systems Engineer, Electrical/ITS-Transportation Engineering, Gord and Associates, Inc, Tampa, FL, 2008 - 2009
Research Assistant, Molecular Parasitology, University of Central Florida, Tampa, FL, 2005 - 2006
Systems Engineer, Electrical/ITS-Transportation Engineering, MasTec North America, Inc./Atlas Traffic Management, Tampa, FL, 2004 - 2008
Intramural Institutional Committee Activities
Associate Member, Graduate School of Biomedical Sciences, The University of Texas MD Anderson Cancer Center, 2024 - 2029
Member, Faculty Senate Extended Hours Taskforce, The University of Texas MD Anderson Cancer Center, 2024 - 2025
Member, Executive Committee of the Faculty Senate (ECFS), The University of Texas MD Anderson Cancer Center, 2024 - 2025
Co-Chair, DoIM Research Grand Rounds Subcommittee, The University of Texas MD Anderson Cancer Center, 2024 - 2025
Member, Department of Internal Medicine Research Grand Rounds Subcommittee, The University of Texas MD Anderson Cancer Center, 2023 - Present
Member, Department of Internal Medicine Research Committee, The University of Texas MD Anderson Cancer Center, 2023 - Present
Chair, Faculty Senate Travel Subcommittee, The University of Texas MD Anderson Cancer Center, 2023 - 2025
Member, Faculty Senate Faculty Led Survey Subcommittee, The University of Texas MD Anderson Cancer Center, 2023
Member, Academic Review Committee, The University of Texas MD Anderson Cancer Center, 2022 - Present
Member, Junior Faculty Committee, The University of Texas MD Anderson Cancer Center, 2022 - Present
Member, Faculty Senate, The University of Texas MD Anderson Cancer Center, 2021 - 2025
Extramural Institutional Committee Activities
Member, International Animal Care & Use Committee, The University of Texas MD Anderson Cancer Center, 2025 - Present
Editorial Activities
Guest Editor, Nutrients, Dietary Interventions for the Prevention and Treatment of Osteoporosis, 2025 - Present
Editorial Board Member, Journal of Bone Oncology, 2025 - 2027
Topic Editor, Tumor and Bone, Orthopaedic Research Society, 2023 - 2025
Topic Editor, Frontiers in Endocrinology, 2022 - 2023
Honors & Awards
| 2026 | Plenary Poster Award, American Society for Bone and Mineral Research |
| 2026 | Cyrus Scholar Finalist, The University of Texas MD Anderson Cancer Center |
| 2021 | Lawrence Award, Bone Disease Program of Texas |
| 2019 | John Haddad Award, American Society for Bone and Mineral Research |
| 2018 | Clinical and Translational Science Kroenke 1st Place Award for Best Poster, Clinical and Translational Science |
| 2018 | Young Investigator Award, American Society for Bone and Mineral Research |
| 2015 | Best Presentation Post-Doctoral Spotlight Symposium, Stony Brook University |
| 2011 | American Society for Bone and Mineral Research Poster Award, American Society for Bone and Mineral Research |
| 2011 | Endocrinology Fellowship Forum, EFF/ADA Fellows Forum on Metabolic Bone Diseases |
| 2001 - 2002 | College of Engineering Dean's List, University of Central Florida |
| 1998 - 2002 | Florida Bright Future's Full Tuition Scholarship, University of Central Florida |
Professional Memberships
Selected Presentations & Talks
Local Presentations
- 2026. Low-Intensity Vibration Preserves Musculoskeletal and Cardiac Function While Maintaining Survival During Bortezomib Therapy in Multiple Myeloma. Conference. MD Anderson Cancer Center: Division of Internal Medicine Cyrus Award. Houston, Texas, US.
- 2026. Assessment of Bone Mechanical Properties to Quantify Bone Strength. Invited. T-Bone Seminar “A seminar for trainees of the Bone Disease Program of Texas“. Houston, Texas, US.
- 2026. Morning Momentum. Panelist. Houston, Texas, US.
- 2025. Vitamin D Physiology and its Impact on Bone. Invited. Endocrine Fellows Seminar Lecture. Houston, Texas, US.
- 2025. Vitamin D and its Impact on Bone. Invited. Endocrine Fellows Seminar, US.
- 2025. Addressing Cancer-Associated Bone Loss with an Engineering Career. Invited. Chapter - Mu Alpha Theta Meeting. Missouri City, Texas, US.
- 2025. Addressing Cancer-Associated Bone Loss with an Engineering Career. Invited. Missouri City, Texas, US.
- 2024. Low Magnitude Mechanical Loads Suppress Cancer-Induced Skeletal Degradation. Invited. Early-Stage Investigator Webinar Series Cancer and Bone Society.
- 2024. A Career in Engineering. Invited. Ronald Thornton Middle School 8th Grade Career Day 2024.
- 2023. Osteomorphs: "The Silent Assailant Following Denosumab Withdrawal". Invited. Houston, TX, US.
- 2022. Skeletal Mechanosensitivity: A Means to Suppress Cancer-Associated Bone Loss. Invited. Houston, TX, US.
- 2021. Attenuating Myeloma-induced Bone Loss and Preserving Muscle Function Utilizing Low Intensity Vibrations and Carfilzomib to Suppress Excess TGF-β in the Bone Marrow Microenvironment. Conference. Houston, TX, US.
- 2021. Attenuating myeloma-induced bone loss and preserving muscle function utilizing low intensity vibrations and carfilzomib to suppress excess TGF-beta in the bone marrow microenvironment. 2021 Rolanette and Berdon Lawrence Bone Disease Program of Texas 17th Annual Scientific Retreat. Houston, Texas, US.
- 2021. Skeletal Mechanosensitivity: A Means to Suppress Cancer-Associated Bone Loss. Invited. Endocrine Educational Series. Houston, TX, US.
- 2021. Mechanical Signals Deter Bone Loss and Muscle Weakness in the Setting of Breast Cancer Bone Metastasis. Invited. Gallick Lab Meeting. Houston, TX, US.
- 2021. Utilizing Mechanical Signals to Suppress Cancer-Associated Bone Loss. Invited. Clinical Research Meeting. Houston, TX, US.
- 2020. Suppressing myeloma-induced bone loss & muscle wasting utilizing low magnitude mechanical signals & carfilzomib to modulate the tumor microenvironment. Invited. 2021 Rolanette and Berdon Lawrence Bone Disease Program of Texas 16th Annual Scientific Retreat, US.
- 2020. Suppressing Myeloma-Induced Bone Loss and Muscle Wasting Utilizing Low Magnitude Mechanical Signals and Carfilzomib to Modulate the Tumor Microenvironment. Conference. Bone Disease Program of Texas Annual Retreat. Houston, TX, US.
National Presentations
- 2026. Musculoskeletal improvement by Low Intensity Vibration in Down Syndrome: A Path Forward?. Invited. Symposium: Lifelong bone health in Down syndrome: new research, new directions T21RS International Conference 2026.
- 2026. Exercise and role of mechanical loading on bone and value for DS. Conference. T21RS International Conference. Denver, Colorado, US.
- 2026. Is Exercise Enough? Closing the Human Performance Gap. Panelist. 2026 Spaceflight Human Optimization & Performance Summit.
- 2026. Mechanical Remodeling of the Musculoskeletal Niche in Myeloma. Invited. 2026 Cancer and Bone Society Conference.
- 2025. Utilizing Low-Magnitude Mechanical Signals to Address Cancer-Induced Bone Loss. Invited. Boise State University, Inspire ME Seminar Series, Department of Mechanical and Biomedical Engineering. Boise, Idaho, US.
- 2025. Low intensity vibration prevents age-related vertebral bone loss and preserves muscle strength in DP16 Down Syndrome mice. Invited. The American Society of Bone and Mineral Research Annual Conference. Seattle, WA, US.
- 2023. Skeletal Mechanosensitivity: A Means to Suppress Cancer-Associated Bone Loss. Invited. Department of Veterinary Physiology and Pharmacology College of Veterinary Medicine and Biomedical Sciences. College Station, Texas, US.
- 2022. Skeletal Mechanosensitivity: A Means to Suppress Cancer-Associated Bone Loss. Invited. Little Rock, AR, US.
- 2021. Low Intensity Vibrations Combined with Zoledronic Acid Reduce Osteolytic Lesion Area from Breast Cancer Bone Metastases. Conference. The American Society for Bone and Mineral Research Annual Conference. San Diego, CA, US.
- 2020. Low Magnitude Mechanical Signals Enhance the Effects of Zoledronic Acid to Reduce Osteolytic Lesion Area and Improve Cardiac Function in a Murine Model of Breast Cancer Bone Metastases. Conference. Cancer and Bone Society Annual Meeting - Virtual Meeting, US.
- 2020. Low Magnitude Mechanical Signals Enhance the Effects of Zoledronic Acid to Reduce Osteolytic Lesion Area and Improve Cardiac Function in a Murine Model of Breast Cancer Bone Metastases. Invited. American Society for Bone and Mineral Research Annual Conference - Virtual Platform. Seattle, WA, US.
- 2019. Low Intensity Vibration Enhances the Effects of Zoledronic Acid on Bone Mass and Strength. Poster. Orlando, FL, US.
- 2019. Mechanical Signals Suppress Osteoclast-Mediated Bone Destruction and Inhibit Myeloma Cell Growth. Invited. Washington, DC, US.
- 2019. Low Magnitude Mechanical Signals Suppress Bone and Muscle Loss in a Murine Model of Complete Estrogen Deprivation Bone and Muscle Crosstalk Meeting. Invited. Indianapolis, IN, US.
- 2019. Utilizing Mechanical Signals to Suppress Cancer-Associated Bone Loss. Invited. Graduate Series Seminar. Indianapolis, IN, US.
- 2019. Low Magnitude Mechanical Signals Influence on Cancer-Associated Bone Loss. Invited. Advances in Mineral Metabolism Annual Meeting. Snowmass, CO, US.
- 2018. Mechanical Signals Alter Myeloma Cell-Cycle and Indirectly Attenuate Resorption. Invited. Indianapolis, IN, US.
- 2017. Effects of LIV Pre-treatment on Musculoskeletal Endpoints in Mice Following Complete Estrogen Deprivation. Conference. Effects of LIV Pre-treatment on Musculoskeletal Endpoints in Mice Following Complete Estrogen Deprivation. St. Louis, MO, US.
- 2017. Low Intensity Vibrations are Associated with Increased Strength, Reduced Adiposity, and Improved Glucose Tolerance in Mice with Complete Estrogen Deprivation. Poster. Denver, CO, US.
- 2017. Effects of LIV Pre-treatment on Musculoskeletal Endpoints in Mice Following Complete Estrogen Deprivation. Invited. Indianapolis, IN, US.
- 2016. The Effects of Low Magnitude Mechanical Signals on Myeloma-induced Osteolysis are Both Anti-resorptive and Systemic. Conference. Atlanta, GA, US.
- 2016. Exercise Shrinks Marrow Adipocytes by Burning Fat. Conference. Atlanta, GA, US.
- 2015. Mechanical Signals: Making Strides Against Cancer-Induced Osteoporosis. Invited. Post-Doctoral Spotlight Symposium. Stony Brook, NY, US.
- 2015. Low Intensity Mechanical Signals Slow Tumor Progression and Osteolysis in a Murine Model of Multiple Myeloma. Poster. Seattle, WA, US.
- 2014. Sleeve Gastrectomy Compromises Skeletal Morphology and Influences Bone Marrow of Obese Rats. Invited. American Society for Metabolic and Bariatric Surgery 31st Annual Meeting. Boston, MA, US.
- 2014. Sleeve Gastrectomy on Obese Rats Reduces the Quantity of Cortical Bone at the Mid Diaphysis. Conference. San Antonio, TX, US.
- 2014. Mechanical Signals Improve Bone Quality Compromised by Type 2 Diabetes, Potentially by Enhancing the Bone Marrow Mesenchymal Stem Cell Population and its Paracrine Regulation of Bone-forming Osteoblasts. Conference. Houston, TX, US.
- 2014. Osteopenia and Osteolysis Resulting from Multiple Myeloma Partially Recovered Following Low Intensity Mechanical Signaling Intervention. Poster. Houston, TX, US.
- 2013. Immunomodulatory Role of Mechanical Signals in Regulating the Expansion of Hematopoietic Precursors in a Murine Model of Multiple Myeloma. Poster. Baltimore, MD, US.
- 2013. Immunomodulatory Role of Mechanical Signals in Regulating the Expansion of Hematopoietic Precursors in a Murine Model of Multiple Myeloma. Poster. Miami, FL, US.
- 2012. Preservation of Bone Mass and Longevity in an Aged Murine Model of Spontaneous Granulosa Cell Ovarian Cancer Following Daily Bouts of Low Magnitude Mechanical Signals. Poster. Preservation of Bone Mass and Longevity in an Aged Murine Model of Spontaneous Granulosa Cell Ovarian Cancer Following Daily Bouts of Low Magnitude Mechanical Signals. Bronx, NY, US.
- 2011. Mechanical Signals Partially Preserve Bone Quality in Animal Models of Ovarian Cancer While Promoting the Mesenchymal Progenitor Pool's Efficacy in Slowing Complications of the Disease. Poster. San Diego, CA, US.
- 2011. Preservation of Bone Mass and Life Expectancy in an Aged Murine Model of Spontaneous Granulosa Cell Ovarian Cancer Following Daily Bouts of Low Magnitude Mechanical Signals. Conference. Chicago, IL, US.
International Presentations
- 2025. The Effects of Low Magnitude Mechanical Loading on Preserving Bone and Muscle Function in Myeloma-Bearing Mice Being Treated with Proteasome Inhibitor. Invited. Joint Meeting of the Cancer and Bone Society Asia-Pacific Conference and The 13th Annual Seoul Symposium on Bone Health and the 37th Congress of the Korean Society for Bone and Mineral Research. Seoul, KR.
- 2024. Bone Loss and Muscle Weakness in Myeloma-Bearing Mice Treated with Proteasome Inhibitor is Partially Attenuated with Low Intensity Vibration. Invited. Cancer and Bone Society Annual Meeting. Sheffield, GB.
- 2018. Mechanical Signals Preserve Bone and Muscle While Suppressing Adiposity in a Murine Model of Complete Estrogen Deprivation. Conference. American Society for Bone and Mineral Research Annual Conference. Montreal, CA.
- 2018. Mechanical Signals Retain Musculoskeletal Endpoints While Suppressing Adiposity in a Murine Model of Compete Estrogen Deprivation. Invited. MolPharm and Cancer and Bone Society Annual Meetings. Oxford, GB.
Grant & Contract Support
| Date: | 2027 - 2028 |
| Title: | Low Intensity Vibration as a Non-Drug Intervention to Inhibit Checkpoint Blockade on Multiple Myeloma |
| Funding Source: | American Cancer Society |
| Role: | PI |
| Date: | 2026 - 2029 |
| Title: | Bioresorbable bone cement for percutaneous vertebral augmentation in metastatic breast cancer |
| Funding Source: | CPRIT |
| Role: | Co-PI |
| Date: | 2026 - 2028 |
| Title: | Mechanical Rewiring of the Myeloma Tumor Niche for Bone Repair and Sustained Remission |
| Funding Source: | NIH |
| Role: | Co-PI |
| Date: | 2026 - 2028 |
| Title: | Assessing Acute and Long-Term Changes in Bone Microarchitecture and Body Composition in Melanoma Patients Undergoing Immune Checkpoint Inhibitor Therapy Using HRpQCT and DXA - Cancer Survivorship |
| Funding Source: | The University of Texas MD Anderson Cancer Center |
| Role: | PI |
| Date: | 2026 - 2027 |
| Title: | Low-Intensity Vibration (LIV) for Prevention of GLP-1 Receptor Agonist–Induced Sarcopenia and Bone Loss in Diet-Induced Obesity Mice |
| Funding Source: | Research Foundation of the State University of New York at Stony Brook University |
| Role: | PI |
| Date: | 2025 - Present |
| Title: | The Effects of Low Magnitude Mechanical Signals on Suppressing Musculoskeletal Degeneration in a Murine Model of Prostate Cancer Undergoing Androgen Deprivation Therapy |
| Funding Source: | Prostate Cancer Foundation |
| Role: | Early-Stage Investigator |
| Date: | 2025 - 2030 |
| Title: | Exercise, Diabetes Therapy, and Musculoskeletal Health |
| Funding Source: | NIH |
| Role: | Co-I, PDPI (10%) |
| Date: | 2024 - 2027 |
| Title: | Disrupting tumor-bone crosstalk to overcome solid cancer-associated mortality and morbidity; Project 3: Disrupting TGFBI to overcome bone metastasis progression |
| Funding Source: | CPRIT, MIRA |
| Role: | Co-I, (15%) |
| Date: | 2024 - Present |
| Title: | The role of the mechanical properties of the bone microenvironment on renal cell carcinoma bone metastases |
| Funding Source: | DoD |
| Role: | PI |
| Date: | 2024 - 2029 |
| Title: | Role of RET Mutations in medullary thyroid cancer bone metastases |
| Funding Source: | NIH/NCI |
| Role: | Co-I, (10%) |
| Date: | 2024 - 2027 |
| Title: | Role of bone-derived TGF-beta in breast cancer-associated cognitive dysfunction |
| Funding Source: | CPRIT, MIRA |
| Role: | Co-I, (10%) |
| Date: | 2022 - 2026 |
| Title: | Attenuating Myeloma-induced Bone Loss and Preserving Muscle Function Utilizing Low Intensity Vibrations and Carfilzomib to Suppress Excess TGF-β in the Bone Marrow Microenvironment |
| Funding Source: | Bone Disease Program of Texas |
| Role: | PI |
| Date: | 2021 - 2022 |
| Title: | Center for Clinical and Translational Sciences Preclinical Modeling Pilot Program Award - The Effects of Low Intensity Vibration on Suppressing Musculoskeletal Degeneration in Mice Undergoing Androgen Deprivation |
| Funding Source: | NIH/NCATS |
| Role: | PI |
| Date: | 2020 - 2027 |
| Title: | Metabolic complications of cancer and cancer treatment-induced bone destruction: Role of TGFβ-mediated oxidation |
| Funding Source: | CPRIT |
| Role: | Co-I |
| Date: | 2020 - 2025 |
| Title: | Cancer Research Prevention Institute of Texas (CPRIT) RR190108 Established Investigator Award |
| Funding Source: | Cancer Prevention & Research Institute of Texas (CPRIT) |
| Role: | Co-I |
| ID: | RR190108 |
| Date: | 2017 - 2019 |
| Title: | Mitigating myeloma-induced muscle wasting using mechanical signals by modulating the tumor microenvironment |
| Funding Source: | CTSI |
| Role: | Postdoctoral Fellow, (10%) |
| ID: | TL1/UL1-TR002531 |
| Date: | 2016 - 2020 |
| Title: | Effects of low magnitude mechanical signals on breast cancer metastasis |
| Funding Source: | Department of Defense (DOD) |
| Role: | Postdoctoral Fellow |
| ID: | DOD BC150678 |
| Date: | 2015 - 2016 |
| Title: | Commercialization Grant |
| Funding Source: | Stony Brook University Center for Biotechnology (REACH) Commercialization Grant |
| Role: | Research Scientist, (100%) |
Selected Publications
Peer-Reviewed Articles
- Pagnotti, GM, Trivedi, T, Wright, LE, John, S, Murthy, S, Pattyn, RR, Willis, MS, She, Y, Suresh, S, Touray, AF, Thompson, WR, Rubin, CT, Mohammad, KS, Guise, TA. Low intensity vibration with zoledronate reduces musculoskeletal weakness and adiposity in estrogen deprived female mice. Nature communications 17(1), 2026. e-Pub 2026. PMID: 41559081.
- Suryadevara, V, Krehbial, CJ, Valiya, AK, Vang, M, Balanta-Melo, J, Eleniste, PP, Posritong, S, Hong, JM, Chester, K, Pagnotti, GM, Bellido, T, Willis, MS, Bruzzaniti, A. Presenilin L166P Mutation, a Model of Familial Alzheimer's Disease, Leads to Early Onset Bone Loss. Comprehensive Physiology 16(1), 2026. e-Pub 2026. PMID: 41496612.
- Bagheri-Yarmand R, Pagnotti GM, Kidd JL, Ramirez DA, Trivedi T, Guerra L, Wang Z, Cruz LM, Moehle JM, Jebaraj YS, Wan X, Song JH, Bassett R, Lin SH, Hu MI, Sherman SI, Hofmann MC, Guise TA. Activating RET Mutations Promotes Osteoblastic Bone Metastases in Medullary Thyroid Cancer. bioRxiv, 2025. e-Pub 2025. PMID: 40791374.
- Chan, ME, Ashdown, C, Strait, L, Pasumarthy, S, Hassan, A, Crimarco, S, Singh, C, Patel, VS, Pagnotti, GM, Khan, O, Uzer, G, Rubin, CT. Low intensity mechanical signals promote proliferation in a cell-specific manner. Mechanobiology in Medicine 2(4), 2024. e-Pub 2024. PMID: 39717386.
- Plett PA, Chua HL, Wu T, Sampson CH, Guise TA, Wright L, Pagnotti GM, Feng H, Chin-Sinex H, Pike F, Cox GN, MacVittie TJ, Sandusky G, Orschell CM. Effect of age at time of irradiation, sex, genetic diversity, and granulopoietic cytokine radiomitigation on lifespan and lymphoma development in murine H-ARS survivors. Radiation Research 202(3):580-598, 2024. e-Pub 2024. PMID: 39099001.
- McGrath C, Little-Letsinger SE, Pagnotti GM, Sen B, Xie Z, Uzer G, Uzer GB, Zong X, Styner MA, Rubin J, Styner M. Diet-Stimulated Marrow Adiposity Fails to Worsen Early, Age-Related Bone Loss. Obesity Facts 17(2):145-157, 2024. e-Pub 2024. PMID: 38224679.
- Chan ME, Ashdown C, Strait L, Pasumarthy S, Hassan A, Crimarco S, Singh C, Patel VS, Pagnotti GM, Khan O, Uzer G, Rubin CT. Low intensity mechanical signals promote proliferation in a cell-specific manner: Tailoring a non-drug strategy to enhance biomanufacturing yields. Mechanobiology in Medicine, 2024. e-Pub 2024. PMID: 37461507.
- Fu J, Li S, Ma H, Yang J, Pagnotti GM, Brown LM, Weiss SJ, Mapara MY, Lentzsch S. The checkpoint inhibitor PD-1H/VISTA controls osteoclast-mediated multiple myeloma bone disease. Nat Commun 14(1):4271, 2023. e-Pub 2023. PMID: 37460553.
- Trivedi T, Manaa M, John S, Reiken S, Murthy S, Pagnotti GM, Dole NS, She Y, Suresh S, Hain BA, Regan J, Ofer R, Wright L, Robling A, Cao X, Alliston T, Marks AR, Waning DL, Mohammad KS, Guise TA. Zoledronic acid improves bone quality and muscle function in a high bone turnover state. bioRxiv, 2023. e-Pub 2023. PMID: 37333318.
- Pagnotti GM, Trivedi T, Wright LE, John SK, Murthy S, Pattyn RR, Willis MS, She Y, Suresh S, Thompson WR, Rubin CT, Mohammad KS, Guise TA. Low-Magnitude Mechanical Signals Combined with Zoledronic Acid Reduce Musculoskeletal Weakness and Adiposity in Estrogen-Deprived Mice. bioRxiv, 2023. e-Pub 2023. PMID: 36993656.
- Nagata Y, Miyagawa K, Ohata Y, Petrusca DN, Pagnotti GM, Mohammad KS, Guise TA, Windle JJ, David Roodman G, Kurihara N. Increased S1P expression in osteoclasts enhances bone formation in an animal model of Paget's disease. J Cell Biochem 122(3-4):335-348, 2021. e-Pub 2021. PMID: 33107091.
- Yi X, Wright LE, Pagnotti GM, Uzer G, Powell KM, Wallace J, Sankar U, Rubin CT, Mohammad KS, Guise TA, Thompson WR. Mechanical suppression of breast cancer cell invasion and paracrine signaling to osteoclasts requires nucleo-cytoskeletal connectivity. Bone Research 8(1), 2020. e-Pub 2020. PMID: 33298883.
- Pagnotti GM, Haider A, Yang A, Cottell KE, Tuppo CM, Tong KY, Pryor AD, Rubin CT, Chan ME. Postural Stability in Obese Preoperative Bariatric Patients Using Static and Dynamic Evaluation. Obes Facts 13(5):1-15, 2020. e-Pub 2020. PMID: 33080591.
- Pagnotti GM, Atkinson RM, Romeiser J, Akalin A, Korman MB, Shroyer KR. B7-H4 is Inversely Correlated with T-Cell Infiltration in Clear Cell but Not Serous or Endometrioid Ovarian Cancer. Appl Immunohistochem Mol Morphol 27(7):515-522, 2019. e-Pub 2019. PMID: 29189263.
- Patel VS, Chan ME, Pagnotti GM, Frechette DM, Rubin J, Rubin CT. Incorporating Refractory Period in Mechanical Stimulation Mitigates Obesity-Induced Adipose Tissue Dysfunction in Adult Mice. Obesity (Silver Spring) 10(10):1745-1753, 2017. e-Pub 2017. PMID: 28840647.
- Styner M, Pagnotti GM, McGrath C, Wu X, Sen B, Uzer G, Xie Z, Zong X, Styner MA, Rubin CT, Rubin J. Exercise Decreases Marrow Adipose Tissue Through B-Oxidation in Obese Running Mice. J Bone Miner Res 8(8):1692-1702, 2017. e-Pub 2017. PMID: 28436105.
- Altieri MS, Pagnotti GM, Corthals A, Shroyer K, Pryor AD, Talamini M, Telem DA. Autologous Augmentation of Hiatal Hernia Repair with Filtered Platelet Concentrate Improves Tissue Remodeling in a Swine Model. Surg Endosc 31(4):1591-98, 2017. e-Pub 2017. PMID: 27924393.
- Pagnotti GM, Chan ME, Adler BJ, Shroyer KR, Rubin J, Bain SD, Rubin CT. Low intensity vibration mitigates tumor progression and protects bone quantity and quality in a murine model of myeloma. Bone 90:69-79, 2016. e-Pub 2016. PMID: 27262776.
- Wright LE, Ottewell PD, Rucci N, Peyruchaud O, Pagnotti GM, Chiechi A, Buijs JT, Sterling JA. Murine models of breast cancer bone metastasis. Bonekey Rep 5:804, 2016. e-Pub 2016. PMID: 27867497.
- Altieri MS, Shroyer KR, Pryor A, Pagnotti GM, Ete Chan M, Talamini M, Telem DA. The association between sleeve gastrectomy and histopathologic changes consistent with esophagitis in a rodent model. Surg Obes Relat Dis 11(6):1289-94, 2015. e-Pub 2015. PMID: 26048523.
- Wallace IJ, Pagnotti GM, Rubin-Sigler J, Naeher M, Copes LE, Judex S, Rubin CT, Demes B. Focal enhancement of the skeleton to exercise correlates with responsivity of bone marrow mesenchymal stem cells rather than peak external forces. J Exp Biol 218(Pt 19):3002-9, 2015. e-Pub 2015. PMID: 26232415.
- Styner M, Pagnotti GM, Galior K, Wu X, Thompson WR, Uzer G, Sen B, Xie Z, Horowitz MC, Styner MA, Rubin C, Rubin J. Exercise Regulation of Marrow Fat in the Setting of PPARγ Agonist Treatment in Female C57BL/6 Mice. Endocrinology 156(8):2753-61, 2015. e-Pub 2015. PMID: 26052898.
- Styner M, Thompson WR, Galior K, Uzer G, Wu X, Kadari S, Case N, Xie Z, Sen B, Romaine A, Pagnotti GM, Rubin CT, Styner MA, Horowitz MC, Rubin J. Bone marrow fat accumulation accelerated by high fat diet is suppressed by exercise. Bone 64(64):39-46, 2014. e-Pub 2014. PMID: 24709686.
- Adler BJ, Green DE, Pagnotti GM, Chan ME, Rubin CT. High fat diet rapidly suppresses B lymphopoiesis by disrupting the supportive capacity of the bone marrow niche. PLoS One 9(3):e90639, 2014. e-Pub 2014. PMID: 24595332.
- Pagnotti GM, Adler BJ, Green DE, Chan ME, Frechette DM, Shroyer KR, Beamer WG, Rubin J, Rubin CT. Low magnitude mechanical signals mitigate osteopenia without compromising longevity in an aged murine model of spontaneous granulosa cell ovarian cancer. Bone 51(3):570-7, 2012. e-Pub 2012. PMID: 22584009.
- Ayong L, Pagnotti GM, Tobon AB, Chakrabarti D. Identification of Plasmodium falciparum family of SNAREs. Mol Biochem Parasitol 152(2):113:22, 2007. e-Pub 2007. PMID: 17240462.
Invited Articles
- Edwards, DN, Patel, S, Pagnotti, GM. Cutting edge developments in bone oncology – Highlights from the Cancer and Bone Society 2024 annual meeting. Journal of Bone Oncology 55, 2025. e-Pub 2025. PMID: 41466841.
- Pagnotti GM, Thompson WR, Guise TA, Rubin CT. Suppression of Cancer-Associated Bone Loss Through Dynamic Mechanical Loading. Bone 150:115998, 2021. e-Pub 2021. PMID: 33971314.
Review Articles
- Iyer, PC, Kikani, NJ, Khan, S, Chaudhari, A, Pagnotti, GM, Best, CJ, Weitzman, SP, Mehta, PB, Lavis, VR, Thosani, S, Gandhi, A, Aguirre, RS, Varghese, J, Guise, TA, Dadu, R. The evolving management of endocrine disorders induced by checkpoint inhibitors. Expert Review of Endocrinology and Metabolism 21(1):29-41, 2026. e-Pub 2026. PMID: 41307239.
- Pagnotti GM, Trivedi T, Mohammad KS. Translational Strategies to Target Metastatic Bone Disease. Cells 11(8), 2022. e-Pub 2022. PMID: 35455987.
- Little-Letsinger SE, Rubin J, Diekman B, Rubin CT, McGrath C, Pagnotti GM, Klett EL, Styner M. Exercise to Mend Aged-tissue Crosstalk in Bone Targeting Osteoporosis & Osteoarthritis. Semin Cell Dev Biol 123:22-35, 2022. e-Pub 2022. PMID: 34489173.
- Trivedi T, Pagnotti GM, Guise TA, Mohammad KS. The Role of TGF-β in Bone Metastases. Biomolecules 11(11):1643, 2021. e-Pub 2021. PMID: 34827641.
- Little-Letsinger SE, Pagnotti GM, McGrath C, Styner M. Exercise and Diet: Uncovering Prospective Mediators of Skeletal Fragility in Bone and Marrow Adipose Tissue. Curr Osteoporos Rep 18(6):774-789, 2020. e-Pub 2020. PMID: 33068251.
- Pagnotti GM, Styner M, Uzer G, Patel VS, Wright LE, Ness KK, Guise TA, Rubin J, Rubin CT. Combating Osteoporosis and Obesity with Exercise: Leveraging Cell Mechanosensitivity. Nat Rev Endocrinol 15(6):339-355, 2019. e-Pub 2019. PMID: 30814687.
- Pagnotti GM, Styner M. Exercise regulation of marrow adipose tissue. Front Endocrinol (Lausanne) 7(JUL):94, 2016. e-Pub 2016. PMID: 27471493.
Other Articles
- Pagnotti GM, Guise TA Commentary on: A Mechanosensitive Peri-Arteriolar Niche for Osteogenesis and Lymphopoiesis.
Abstracts
- McGrath C, Little-Letsinger S, Pagnotti GM, Sen B, Xie Z, Uzer G, Uzer GB, Zong X, Ehrmann BM, Wallace D, Styner MA, Rubin J, Styner M. Diet Stimulated Marrow Adiposity Fails to Worsen Early, Age-Related Bone Loss; American Society of Bone and Mineral Research, 2023. e-Pub 2023.
- Fu J, Li S, Ma H, Yang J, Brown L, Pagnotti GM, Weiss S, Mapara M, Lentzsch S. The Novel Role of Checkpoint Inhibitor PD-1H/VISTA in Osteoclast Cytoskeleton Regulation and Multiple Myeloma Bone Disease, 2022. e-Pub 2022.
- Pagnotti GM, John SK, Trivedi T, Wilson RG, She Y, Wright LE, Murthy S, Suresh S, Rubin CT, Thompson WR, Mohammad KS, Guise TA. Low intensity vibration combined with zoledronic acid improves bone mass and fracture resistance in completely estrogen-deprived mice, 2022. e-Pub 2022.
- Fu J, Li S, Ma H, Jun Yang J, Brown L, Pagnotti GM, Weiss S, Mapara M, Lentzsch S. The role of checkpoint inhibitor PD-1H/VISTA in osteoclast activation and bone disease in multiple myeloma, 2022. e-Pub 2022.
- Pagnotti GM. Fate Selection Election And Viability of Mesenchymal and Hematopoietics Stem Cell Populations, Disrupted By Obesity, Aging and Disuse, Are Rescued By Low Intensity Mechanical Signals. Orthopaedic Proceedings 95-B No.SUPP_16(Trauma):2-2, 2013. e-Pub 2013.
- Rubin CT, Chan ME, Adler BJ, Green DE, Pagnotti GM, Judex S, Rubin JE. Fate Selection and Viability of Mesenchymal and Hematopoietic Stem Cell Populations, Disrupted by Obesity, Aging and Disuse, are Rescued by Low Intensity Mechanical Signals. Orthopaedic Proceedings SUPP 16(95-B), 2013. e-Pub 2013.
- Schuman C, Pagnotti GM, Guise TA, Schilling B. Proteomics of Bone Carrying Metastatic Breast Cancer Lesions from Archival Formalin-Fixed Paraffin Embedded (FFPE) Tissue Blocks Unveils Striking Skeletal Remodeling. American Society of Mass Spectrometry.
- . Deletion of the Auxiliary Voltage-Sensitive Calcium Channel α2δ1 Subunit Pushes Mesenchymal Stem Cells Towards an Adipogenic over Osteogenic Lineage Commitment. The American Society for Bone and Mineral Research Annual Conference.
- . RET Promotes Osteoblastic Bone Metastases in Medullary Thyroid Cancer. The American Society for Bone and Mineral Research Annual Conference.
- pagnotti, g. Low Intensity Vibrations Combined with Zoledronic Acid Reduce Osteolytic Lesion Area from Breast Cancer Bone Metastases. The American Society for Bone and Mineral Research Annual Conference.
- PhD JF, Li S, MD PhD HM, Jun Yang MS, Pagnotti PhD GM, MD PhD SJW, MD PhD MYM, MD PhD SL. Checkpoint Inhibitor PD-1H/VISTA Mediates MMP-13 Induced Osteoclast Activation and Multiple Myeloma Bone Disease. 63rd ASH Annual Meeting and Exposition.
- Trivedi T, Bacha D, He W, John S, Murthy S, Suresh S, Pagnotti G, She Y, Mohammad K, Guise T. Sex-based Differential Response of Long-term High Fat Diet to Energy Metabolism, Musculoskeletal and Cardiac Function in Aged Mice. American Society for Bone and Mineral Research 2022 Annual Meeting.
- Bagheri-Yarmand R, Pagnotti GM, Trivedi T, Martinez L, Martinez J, Kuo TT, Guerra LD, Song JH, Lin S, Guise TA. Role of RET in the pathogenesis of osteoblastic bone metastases due to medullary thyroid cancer. American Society for Bone and Mineral Research 2022 Annual Meeting.
- Shi L, Kuo T, Martinez J, Suresh S, Van V, Pagnotti G, Trivedi T, Bacha DS, Guerra L, Xu C, Guise T. Excess TGF-ß is associated with cardiac dysfunction due to oxidative of RyR, Ca2+ leak and mitochondrial dysfunction. American Society for Bone and Mineral Research 2022 Annual Meeting.
- Bagheri-Yarmand R, Pagnotti GM, Guise TA. RET promotes osteoblastic lesions in medullary thyroid carcinoma bone metastasis by increasing osteoblast differentiation inhibited by small-molecule ONC201. American Thyroid Association Annual Conference 2022.
- Pagnotti GM, Bagheri-Yarmand R. RET promotes osteoblastic lesions in medullary thyroid carcinoma bone metastasis by increasing osteoblast differentiation inhibited by small-molecular ONC201. American Thyroid Association Annual Conference.
- Shi L, Suresh S, Kuo T, Singh A, Martinez J, Trivedi T, Pagnotti GM, Guerra LD, Cao X, Guise TA. Bone-derived excess TGF-ß release is associated with cognitive dysfunction due to oxidation of RyR, Ca2+ leak and mitochondrial dysfunction. Cancer and Bone Society 2023 Annual Meeting.
- Trivedi T, Pagnotti GM, Suresh S, She Y, Murthy S, Martinez J, Molina C, Mohammad KS, A Guise AT. Complete estrogen-deprived athymic nude mice are susceptible to changes in metabolism and musculoskeletal function mediated by a high-fat-diet. Cancer and Bone Society 2023 Annual Meeting.
- Shi L, Kuo T, Martinez J, Suresh S, Trivedi T, Pagnotti GM, Guerra LD, Cao X, Guise TA. Bone-derived TGF-ß release is associated with cardiac dysfunction due to oxidation of SR calcium gatekeepers, Ca2+ leak and mitochondrial dysfunction. American Association for Cancer Research Annual Meeting 2023.
- Bagheri-Yarmand R, Pagnotti GM, Trivedi T, Guerra L, Kidd JL, Martinez JA, Song JH, Lin S, Guise TA. Activating RET mutations in medullary thyroid cancer cells promotes osteoblastic bone metastasis by inhibiting osteoclastogenesis and stimulating osteoblast activity. Cancer and Bone Society 2023 Annual Meeting.
- Pagnotti GM, Touray AF, Wan X, Guise TA. Bone Loss and Muscle Weakness in Myeloma-Bearing Mice Treated with Proteasome Inhibitor is Partially Attenuated with Low Intensity Vibration Peer-reviewed conference presentation. Cancer and Bone Society Annual Meeting.
- Bagheri-Yarmand R, Kidd JL, Pagnotti GM, Trivedi T, Guerra L, Martinez JA, Wan X, Song JH, Lin S, Guise TA. Activating RET Mutations Promotes Osteoblastic Bone Metastasis by Stimulating Osteoblast Activity and Inhibiting Osteoclastogenesis via Regulation of Osteoprotegerin. American Society for Bone and Mineral Research Annual Meeting.
- Wan X, Corn P, Yang J, Labanca E, Fong E, Pagnotti GM, Yuan S, Troncoso P, Logothetis C, Navone N, Guise TA. Dovitinib Mitigated Prostate Cancer Bone Metastases via Inhibiting the FGF Pathway. Cancer and Bone Society Annual Meeting.
- Bagheri-Yarmand R, Kidd JL, Pagnotti GM, Trivedi T, Guerra L, Martinez JA, Wan X, Song JH, Lin S, Guise TA. Activating RET mutations promotes osteoblastic bone metastasis by inhibiting osteoclastogenesis and stimulating osteoblast activity via regulation of osteoprotegerin. American Association for Cancer Research Annual Meeting.
- Bagheri-Yarmand R, Kidd JL, Pagnotti GM, Trivedi T, Guerra L, Martinez JA, Wan X, Song JH, Lin S, Guise TA. Activating RET mutations promotes osteoblastic bone metastasis by inhibiting osteoclastogenesis and stimulating osteoblast activity via regulation of osteoprotegerin. 2024 Rolanette and Berdon Lawrence Bone disease Program of Texas 19th Annual Meeting Annual Scientific Retreat.
- Pagnotti GM, Touray A, Wan X, Guise TA. Low Intensity Vibration Attenuates Local and Systemic Bone Loss in Myeloma-Bearing Mice Treated with Proteosome Inhibitor. 2024 Rolanette and Berdon Lawrence Bone disease Program of Texas 19th Annual Scientific Retreat.
- Bagheri-Yarmand R, Kidd JL, Pagnotti GM, Trivedi T, Guerra L, Martinez JA, Wan X, Song JH, Lin S, Guise TA. Activating RET Mutations Promotes Osteoblastic Bone Metastasis by Stimulating Osteoblast Activity and Inhibiting Osteoclastogenesis via Regulation of Osteoprotegerin. American Society for Bone and Mineral Research Annual Meeting 2024.
- Zhouyao H, Pagnotti GM. Sever reduction in trabecular bone mass following global deletion of MFSD14A. ASBMR 2026 Annual Meeting.
- Yaun S, Pagnotti GM. Bone -Derived TGF-B Promotes Anaplastic Thyroid Cancer Bone Metatases: Therapeutic Effects of Zoledronate and Bone-Targeted TGF-B Inhibition on ATC Bone-Immune Microenvironment. ASBMR 2026 Annual Meeting.
- Pagnotti GM, Dadbin A, Touray AF, Wang X, Wan X, Guise TA. Low Intensity Vibration Coupled with Proteasome Inhibitor Improves Survival and Mitigates Cardiac Dysfunction and Stems Bone Loss. Lawrence Family Bone Disease Program of Texas Research Retreat, MD Anderson Cancer Center 2026.
- Wan X, Corn P, Yang J, Labanca E, Pagnotti G, Yuan S, Troncoso P, Logothetis C, Navone N, Guise T. Targeting FGF Signaling with Dovitinib to Suppress Prostate Cancer Bone Metastases. 2026 DoIM Research Retreat, MD Anderson Cancer Center.
- Pagnotti GM, Dadbin A, Touray AF, Wang X, Wan X, Guise TA. Low-Intensity Vibration Preserves Musculoskeletal and Cardiac Function While Maintaining Survival During Bortezomib Therapy in Multiple Myeloma. MD Anderson Cancer Center: Division of Internal Medicine Annual Retreat 2026.
- Schuman C, Pagnotti GM, Guise TA, Schilling B. Countering Metastatic Breast Cancer in Bone with Combined Therapies Investigated via Proteomics of Formalin-Fixed Paraffin Embedded Tissues. American Society for Mass Spectrometry 2026.
- Pagnotti GM, Dadbin A, Touray AF, Wang X, Wan X, Guise TA. Low Intensity Vibration Preserves Musculoskeletal and Cardiac Function and Conserves Survival in Multiple Myeloma-Bearing Mice Under Bortezomib Therapy. American Society for Bone and Mineral Research Annual Meeting 2026.
- . Immunomodulatory Role of Mechanical Signals in Regulating the Expansion of Hematopoietic Precursors in a Murine Model of Multiple Myeloma. American Society for Bone and Mineral Research.
- . Improved Bone Quality in Diet-Induced Obesity by Low Intensity Vibrations is paralleled by Suppressed Bone Marrow Adiposity and Reduced Pro-Inflammatory State of Mesenchymal Stem Cells. American Society for Bone and Mineral Research.
- . Running Decreases Marrow Adipose Tissue in Chow and High Fat Fed Mice. American Society for Bone and Mineral Research.
- . Immunomodulatory Role of Mechanical Signals in Regulating the Expansion of Hematopoietic Precursors in a Murine Model of Multiple Myeloma. International Bone and Mineral Research Cancer-Induced Bone Disease.
- . Sleeve Gastrectomy on Obese Rats Impairs Trabecular Bone in Quantity and Quality. Biomedical Engineering Society.
- . Using Virtual Reality to Improve the Compliance of Children and Adults to Daily Vibration Treatment While Measuring Treatment Efficacy. Biomedical Engineering Society.
- . Mechanical Signals Improve Bone Quality Compromised by Type 2 Diabetes, Potentially by Enhancing the Bone Marrow Mesenchymal Stem Cell Population and its Paracrine Regulation of Bone-forming Osteoblasts. American Society for Bone and Mineral Research.
- . Osteopenia and Osteolysis Resulting from Multiple Myeloma Partially Recovered Following Low Intensity Mechanical Signaling Intervention. American Society for Bone and Mineral Research.
- . Sleeve Gastrectomy on Obese Rats Reduces the Quantity of Cortical Bone at the Mid Diaphysis. Biomedical Engineering Society.
- . The Association Between Sleeve Gastrectomy and Histopathologic Changes Consistent with Esophagitis in a Rodent Model. American Society for Metabolic and Bariatric Surgery 31st Annual Meeting.
- . Sleeve Gastrectomy Compromises Skeletal Morphology and Influences Bone Marrow of Obese Rats. American Society for Metabolic and Bariatric Surgery 31st Annual Meeting.
- . Low-Intensity Vibration is Tolerated in Animals with Percutaneously Attached Prosthetics. World Congress of Biomechanics.
- . The Use of Bone Densitometry as a Clinical Tool to Evaluate Healing of a Percutaneous Prosthetic Attachment Implant. World Congress of Biomechanics.
- . Low Magnitude Mechanical Signals Improve Serum Glucose Tolerance and Decrease Adipocyte Size in Obesity. American Diabetes Association.
- . Low Intensity Vibration Amplifies Beneficial Effects of Sleeve Gastrectomy on Bone Marrow Niche. Biomedical Engineering Society.
- . Exercise Regulation of Marrow Fat in the Setting of PPARy Agonist Treatment. American Society for Bone and Mineral Research.
- . The Effects of Low Intensity Vibration on Bone Mineral Density in the Intact Limb of Animals with a Percutaneously Attached Endoprosthesis. Summer Biomechanics, Bioengineering and Biotransport.
- . Low Intensity Mechanical Signals Slow Tumor Progression and Osteolysis in a Murine Model of Multiple Myeloma. American Society for Bone and Mineral Research.
- . Exercise diminishes obesity-associated Marrow fat as quantified by Magnetic Resonance Imaging (MRI). American Society for Bone and Mineral Research.
- . Bodies in Motion: Biomechanical Data Acquisition with a Skeleton Tracking Sensor. Biomedical Engineering Society.
- . Exercise Shrinks Marrow Adipocytes by Burning Fat. American Society for Bone and Mineral Research.
- . The Effects of Low Magnitude Mechanical Signals on Myeloma-induced Osteolysis are Both Anti-resorptive and Systemic. American Society for Bone and Mineral Research.
- Pagnotti GM. Mechanical Signals as a Means to Preserve Bone and Suppress Tumor Progression in Murine Cancer Models. Bone and Mineral Research Seminar.
- . Continuous Cocaine Administration Results in Significant Trabecular Bone Deterioration. Biomedical Engineering Society.
- . Biology Trumps Mechanics: Bone Adaptation to Exercise Correlates More Closely to Bone Marrow Stem Cell Responsivity than Peak Forces. American Association of Physical Anthropologists.
- . Effects of LIV Pre-treatment on Musculoskeletal Endpoints in Mice Following Complete Estrogen Deprivation. Midwest Tumor Microenvironment.
- . Low Intensity Vibrations are Associated with Increased Strength, Reduced Adiposity, and Improved Glucose Tolerance in Mice with Complete Estrogen Deprivation. American Society for Bone and Mineral Research.
- . A Novel ex-vivo Model of Prolonged Osteoblast Suppression in Multiple Myeloma. American Society for Hematology.
- . Mechanical Signals Preserve Bone and Muscle While Suppressing Adiposity in a Murine Model of Complete Estrogen Deprivation. American Society for Bone and Mineral Research Annual Conference.
- . Mechanical Signals Retain Musculoskeletal Endpoints While Suppressing Adiposity in a Murine Model of Compete Estrogen Deprivation. MolPharm and Cancer and Bone Society.
- . Disruption of Nucleo-Cytoskeletal Connectivity Impairs Mechanical Competence of MDA-MB-231 Cells and Regulates Responses to Low Magnitude Mechanical Forces. American Society for Bone and Mineral Research.
- . Mechanical Signals Suppress Osteoclast-Mediated Bone Destruction and Inhibit Myeloma Cell Growth. American Society for Clinical and Translational Science Annual Conference.
- . Low Magnitude Mechanical Signals Influence on Cancer-Associated Bone Loss. Advances in Mineral Metabolism.
- . Low Intensity Vibration Enhances the Effects of Zoledronic Acid on Bone Mass and Strength. American Society for Bone and Mineral Research.
- Andrew M, Laura W, Sutha J, Yun S, Mohamed M, Steven R, Gabriel P, Jenna R, Trupti T, Rachel O, Theresa G, Sukanya S, Sreemala M, Tamara A, Xu C, Khalid M, Alex R, Brian H, David W, Neha D. Zoledronic Acid Improves Bone Quality and Muscle Function in High Bone-Turnover State. Joint Meeting for the Cancer and Bone Society and American Society for Bone and Mineral Research Annual Conference 2020.
- . Low Magnitude Mechanical Signals Enhance the Effects of Zoledronic Acid to Reduce Osteolytic Lesion Area and Improve Cardiac Function in a Murine Model of Breast Cancer Bone Metastases. Cancer and Bone Society.
- . Low Magnitude Mechanical Signals Enhance the Effects of Zoledronic Acid to Reduce Osteolytic Lesion Area and Improve Cardiac Function in a Murine Model of Breast Cancer Bone Metastases. American Society for Bone and Mineral Research Annual Conference - Virtual.
- Trupti T, Theresa G, Laura W, Sutha J, Sukanya S, Sreemala M, Pagnotti Gabriel M, Yun S, Khalid M. Musculoskeletal and metabolic responses to low fat and high fat diet in athymic nude mice. Joint Meeting for the Cancer and Bone Society and American Society for Bone and Mineral Research Annual Conference 2020.
- Pagnotti GM, Thompson WR, Ballinger TA. Skeletal Mechanosensitivity: A Means to Suppress Cancer-Associated Bone Loss. Endocrine Educational Series, The University of Texas MD Anderson Cancer Center.
- Wright, Christian S, Semon KM, Kelly M, Yi X, Pagnotti GM, Hum JM, Robling AG, Frach-Carson MC, R Thompson AW. Deletion of the Auxiliary alpha 2 delta 1 Voltage-Sensitive Calcium Channel Subunit Increases Bone Marrow Adiposity in Mice. American Society for Bone and Mineral Research (ASBMR) 2021 Annual Meeting 37:211-211.
- Khalid M, Sreemala M, Sutha J, Steven R, Asma B, Sarah T, Andrew M, Xu C, Sukanya S, Carmella E, Trupti T, Yun S, Gabriel P, Jennymar R, Theresa G, Jenna R. Bone-derived TGF- impairs glucose metabolism and insulin release by oxidation of RyR2 Ca2+ release channel in pancreatic-cells. Internal Medicine research retreat and Cyrus award.
- Yun S, Sarah T, Xu C, Asma B, Sutha J, Jennymar R, Sreemala M, Khalid M, Andrew M, Jenna R, Gabriel P, Trupti T, Sukanya S, Theresa G, Steven R, Carmella E. Excess TGF-b and high fat diet exacerbate musculoskeletal and metabolic complications of pathologic bone remodeling. Presented at Translating Energy Balance From Bench to Communities: Application of Parallel Animal-Human Studies in Cancer.
- . The Novel Role of Checkpoint Inhibitor PD-1H/VISTA in Osteoclast Activation and Multiple Myeloma Bone Disease. 63rd Annual American Society of Hematology Meeting.
- . The Role of Checkpoint Inhibitor PD-1H/VISTA in Multiple Myeloma Bone Disease. 18th International Myeloma Workshop.
- . Attenuating Myeloma-induced Bone Loss and Preserving Muscle Function Utilizing Low Intensity Vibrations and Carfilzomib to Suppress Excess TGF-β in the Bone Marrow Microenvironment. Bone Disease Program of Texas Research Retreat Conference.
- . Preservation of Bone Mass and Life Expectancy in an Aged Murine Model of Spontaneous Granulosa Cell Ovarian Cancer Following Daily Bouts of Low Magnitude Mechanical Signals. International Bone and Mineral Research Cancer-Induced Bone Disease.
- . Mechanical Signals Partially Preserve Bone Quality in Animal Models of Ovarian Cancer While Promoting the Mesenchymal Progenitor Pool's Efficacy in Slowing Complications of the Disease. American Society for Bone and Mineral Research.
Book Chapters
- Pagnotti GM, Marino S, Petrusca D, Bellido T, Roodman GD, Delgado-Calle J. Role of osteoblasts in cancer-induced bone disease. In: Encyclopedia of Bone Biology, 201-218, 2020.
Web Publications
- Pagnotti GM. Leveraging Cell Mechanosensitivity From Exercise Could Lead to New Strategies for Treating Osteoporosis and Obesity.
- Pagnotti GM. Development Grants Accelerate Commercialization of Biomedical Technology.
- Pagnotti GM. Vibration plates: Are there health benefits?.
Patient Reviews
CV information above last modified September 22, 2026