Gokce Altay Toruner, M.D., Ph.D., FACMG

Peer-Reviewed Articles

1. Loghavi S, Wei Q, Ravandi F, Quesada AE, Routbort MJ, Hu S, Toruner GA, Wang SA, Wang W, Miranda RN, Li S, Xu J, DiNardo CD, Daver N, Kadia TM, Issa GC, Kantarjian HM, Medeiros LJ, Tang G. Optical genome mapping improves the accuracy of classification, risk stratification, and personalized treatment strategies for patients with acute myeloid leukemia. Am J Hematol None(None):None, 2024. PMID: 39016111.
2. Tang G, Wu Y, Lin P, Toruner GA, Hu S, Li S, Qazilbash MH, Orlowski RZ, Ye C, Xu J, Nahmod KA, Medeiros LJ, Tang Z. Cytogenetic Profile in Monoclonal Gammopathy of Undetermined Significance, Smoldering and Symptomatic Multiple Myeloma: A Study of 1087 Patients with Highly Purified Plasma Cells. Cancers (Basel) 15(23), 2023. e-Pub 2023. PMID: 38067393.
3. Esplen HP, Yang RK, Kalia A, Tang Z, Tang G, Medeiros LJ, Toruner GA. Recurrent Somatic Copy Number Alterations and Their Association with Oncogene Expression Levels in High-Grade Ovarian Serous Carcinoma. Life (Basel) 13(11), 2023. e-Pub 2023. PMID: 38004332.
4. Diks J, Tang Z, Altan M, Anderson S, Chen H, Rashid A, Yang RK, Routbort MJ, Patel KP, Toruner GA, Medeiros LJ, Tang G, Luthra R, Roy-Chowdhuri S. Detection of clinically actionable gene fusions by next-generation sequencing-based RNA sequencing of non-small cell lung cancer cytology specimens: A single-center experience with comparison to fluorescence in situ hybridization. Cancer Cytopathol. e-Pub 2023. PMID: 37747438.
5. Rav ES, Wahba A, Patnaik A, Toruner G, Hittle A, Toepfer L, Roth M, Cuglievan B, Nunez C, McCall D. A balancing act: Blinatumomab use in a rare occurrence of Philadelphia chromosome-positive B-cell acute lymphoblastic leukemia in an adolescent patient with Down syndrome. Pediatr Blood Cancer 70(5):e30191, 2023. e-Pub 2023. PMID: 36602024.
6. Tang G, Li S, Toruner GA, Jain P, Tang Z, Hu S, Xu J, Cheng J, Robinson M, Vega F, Medeiros LJ. Clinical impact of 5'MYC or 3'MYC gain/loss detected by FISH in patients with aggressive B-cell lymphomas. Cancer Genet 272-273:1-8, 2023. e-Pub 2022. PMID: 36566629.
7. Tang Z, Wang W, Yang S, El Achi H, Fang H, Nahmod KA, Toruner GA, Xu J, Thakral B, Ayoub E, Issa GC, Yin CC, You MJ, Miranda RN, Khoury JD, Medeiros LJ, Tang G. 3q26.2/MECOM Rearrangements by Pericentric Inv(3): Diagnostic Challenges and Clinicopathologic Features. Cancers (Basel) 15(2), 2023. e-Pub 2023. PMID: 36672407.
8. Yang RK, Chen H, Roy-Chowdhuri S, Rashid A, Alvarez H, Routbort M, Patel KP, Luthra R, Medeiros LJ, Toruner GA. Clinical Testing for Mismatch Repair in Neoplasms Using Multiple Laboratory Methods. Cancers (Basel) 14(19), 2022. e-Pub 2022. PMID: 36230473.
9. Wang X, Tang G, Hu Z, Fang H, Wang W, Tang Z, Toruner GA, Zhou T, DiNardo CD, Garcia-Manero G, Verstovsek S, Bueso-Ramos CE, Medeiros LJ, Hu S. Myeloid neoplasms with 8q24/MYC rearrangement are frequently associated with myelodysplasia, complex karyotype, TP53 alterations, and inferior survival. Br J Haematol. e-Pub 2022. PMID: 35645146.
10. Yin W, Guo M, Tang Z, Toruner GA, Cheng J, Medeiros LJ, Tang G. MET Expression Level in Lung Adenocarcinoma Loosely Correlates with MET Copy Number Gain/Amplification and Is a Poor Predictor of Patient Outcome. Cancers (Basel) 14(10), 2022. e-Pub 2022. PMID: 35626038.
11. Fang H, Toruner GA, Tang Z, Tang G, Weissferdt A, Tashakori M, El Hussein S, Thakral B, Quesada AE, Wang W, Patel KP, Garcia-Manero G, Medeiros LJ, Bueso-Ramos CE, Jelloul FZ. Primary mediastinal germ cell tumor and clonally related and unique hematologic neoplasms with i(12p) and TP53 mutation: A report of two cases. Ann Diagn Pathol 59:151951. e-Pub 2022. PMID: 35489185.
12. Tang G, Zou Y, Wang SA, Borthakur G, Toruner G, Hu S, Li S, Xu J, Medeiros LJ, Tang Z. 3'CBFB deletion in CBFB-rearranged acute myeloid leukemia retains morphological features associated with inv(16), but patients have higher risk of relapse and may require stem cell transplant. Ann Hematol 101(4):847-854, 2022. e-Pub 2022. PMID: 35184217.
13. Saglam O, Cao B, Wang X, Toruner GA, Conejo-Garcia JR. Expression of epigenetic pathway related genes in association with PD-L1, ER/PgR and MLH1 in endometrial carcinoma. PLoS One 17(2):e0264014, 2022. e-Pub 2022. PMID: 35226658.
14. Gouni S, Strati P, Toruner G, Aradhya A, Landgraf R, Bilbao D, Vega F, Agarwal NK. Statins enhance the chemosensitivity of R-CHOP in diffuse large B-cell lymphoma. Leuk Lymphoma:1-12. e-Pub 2021. PMID: 34969327.
15. Zhao M, Medeiros LJ, Wang W, Tang G, Jung HS, Sfamenos SM, Fang H, Toruner GA, Hu S, Yin CC, Lin P, Gu J, Peng G, You MJ, Khoury JD, Wang SA, Tang Z. Newly designed breakapart FISH probe helps to identify cases with true MECOM rearrangement in myeloid malignancies. Cancer Genet 262-263:23-29. e-Pub 2021. PMID: 34974290.
16. Yang RK, Toruner GA, Wang W, Fang H, Issa GC, Wang L, Quesada AE, Thakral B, Patel KP, Peng G, Liu S, Yin CC, Borthakur G, Tang Z, Wang SA, Miranda RN, Khoury JD, Medeiros LJ, Tang G. CBFB Break-Apart FISH Testing: An Analysis of 1629 AML Cases with a Focus on Atypical Findings and Their Implications in Clinical Diagnosis and Management. Cancers (Basel) 13(21), 2021. e-Pub 2021. PMID: 34771519.
17. Toruner GA, Thakral B, Tang Z, Tang G, Medeiros LJ, Oran B. Clonal cytogenetic abnormalities in donor-derived cells after sex mismatched allogeneic stem cell transplantation. Cancer Genet 258-259:120-130. e-Pub 2021. PMID: 34715428.
18. Tang Z, Kanagal-Shamanna R, Tang G, Patel K, Medeiros LJ, Toruner GA. Analytical and clinical performance of chromosomal microarrays compared with FISH panel and conventional karyotyping in patients with chronic lymphocytic leukemia. Leuk Res 108:106616. e-Pub 2021. PMID: 34022744.
19. Manasanch EE, Berrios D, Fountain E, Claussen CM, Chuang T, Kaufman G, Amini B, Bashir Q, Nieto Y, Qazilbash M, Patel K, Thomas SK, Weber DM, Berkova Z, Toruner G, Lin P, Feng L, Lee HC, Orlowski RZ, Kunacheewa C. Gene expression profiling predicts relapse-free and overall survival in newly diagnosed myeloma patients treated with novel therapies. Br J Haematol 192(4):e115-e120, 2021. e-Pub 2021. PMID: 33486754.
20. Yin W, Cheng J, Tang Z, Toruner G, Hu S, Guo M, Robinson M, Medeiros LJ, Tang G. MET Amplification (MET/CEP7 Ratio = 1.8) Is an Independent Poor Prognostic Marker in Patients With Treatment-naive Non-Small-cell Lung Cancer. Clin Lung Cancer. e-Pub 2020. PMID: 33288441.
21. Yin W, Liu W, Guo M, Tang Z, Toruner G, Robinson M, Cheng J, Hu S, Medeiros LJ, Tang G. Acquired MET amplification in non-small cell lung cancer is highly associated with the exposure of EGFR inhibitors and may not affect patients' outcome. Exp Mol Pathol 118(r):104572. e-Pub 2020. PMID: 33189723.
22. Liu W, Burger JA, Xu J, Tang Z, Toruner G, Khanlari M, Medeiros LJ, Tang G. LPL deletion is associated with poorer response to ibrutinib-based treatments and overall survival in TP53-deleted chronic lymphocytic leukemia. Ann Hematol 99(10):2343-2349, 2020. e-Pub 2020. PMID: 32833105.
23. Tang Z, Toruner GA, Tang G, Cameron Yin C, Wang W, Hu S, Thakral B, Wang SA, Miranda RN, Khoury JD, Medeiros LJ. Chronic myeloid leukemia with insertion-derived BCR-ABL1 fusion: redefining complex chromosomal abnormalities by correlation of FISH and karyotype predicts prognosis. Mod Pathol 33(10):2035-2045, 2020. e-Pub 2020. PMID: 32404952.
24. Yilmaz M, Kantarjian HM, Toruner G, Yin CC, Kanagal-Shamanna R, Cortes JE, Issa G, Short NJ, Khoury JD, Garcia-Manero G, Ravandi F, Kadia T, Konopleva M, Wierda WG, Jain N, Estrov Z, Sasaki K, Pierce S, O'Brien SM, Jabbour EJ. Translocation t(1;19)(q23;p13) in adult acute lymphoblastic leukemia - a distinct subtype with favorable prognosis. Leuk Lymphoma:1-5. e-Pub 2020. PMID: 32955970.
25. Chen Z, Hu S, Wang SA, Konopleva M, Tang Z, Xu J, Li S, Toruner G, Thakral B, Medeiros LJ, Tang G. Chronic myeloid leukemia presenting in lymphoblastic crisis, a differential diagnosis with Philadelphia-positive B-lymphoblastic leukemia. Leuk Lymphoma:1-8. e-Pub 2020. PMID: 32700989.
26. Tang Z, Chen H, Hong L, Tang G, Toruner GA, Wang W, Roy Chowdhuri S, Yin W, Jung HS, Gu J, Routbort MJ, Zhang J, Khoury JD, Medeiros LJ. Inconsistent Intersample ALK FISH Results in Patients with Lung Cancer: Analysis of Potential Causes. Cancers (Basel) 12(7), 2020. e-Pub 2020. PMID: 32674491.
27. Xie W, Xu J, Hu S, Li S, Wang W, Cameron Yin C, Toruner G, Tang Z, Jeffrey Medeiros L, Tang G. iAMP21 in acute myeloid leukemia is associated with complex karyotype, TP53 mutation and dismal outcome. Mod Pathol 33(7):1389-1397, 2020. e-Pub 2020. PMID: 32034282.
28. Toruner GA, Tang Z, Tang G, Medeiros LJ, Hu S. Low ALK FISH positive metastatic non-small cell lung cancer (NSCLC) patients have shorter progression-free survival after treatment with ALK inhibitors. Cancer Genet 241:57-60, 2020. e-Pub 2019. PMID: 31870845.
29. Saglam O, Tang Z, Tang G, Medeiros LJ, Toruner GA. KAT6A amplifications are associated with shorter progression-free survival and overall survival in patients with endometrial serous carcinoma. PLoS One 15(9):e0238477, 2020. e-Pub 2020. PMID: 32877461.
30. Chen Z, Sun Y, Xie W, Wang SA, Hu S, Li S, Tang Z, Toruner G, Medeiros LJ, Tang G. Is hyperdiploidy a favorable cytogenetics in adults with B-lymphoblastic leukemia?. Cancer Med 8(9):4093-4099, 2019. e-Pub 2019. PMID: 31173486.
31. Tang Z, Tang G, Hu S, Patel KP, Cameron Yin C, Wang W, Lin P, Toruner GA, Ok CY, Gu J, Lu X, Khoury JD, Jeffrey Medeiros L. Data on MECOM rearrangement-driven chromosomal aberrations in myeloid malignancies. Data Brief 24:104025, 2019. e-Pub 2019. PMID: 31193989.
32. Tang Z, Tang G, Hu S, Patel KP, Yin CC, Wang W, Lin P, Toruner GA, Ok CY, Gu J, Lu X, Khoury JD, Medeiros LJ. Deciphering the complexities of MECOM rearrangement-driven chromosomal aberrations. Cancer Genet 233-234:21-31, 2019. e-Pub 2019. PMID: 31109591.
33. Tang G, Hu S, Wang SA, Xie W, Lin P, Xu J, Toruner G, Zhao M, Gu J, Doty M, Li S, Medeiros LJ, Tang Z. t(3;8)(q26.2;q24) Often Leads to MECOM /MYC Rearrangement and is Commonly Associated with Therapy-Related Myeloid Neoplasms and/or Disease Progression. J Mol Diagn 21(2):343-351, 2019. e-Pub 2018. PMID: 30576868.
34. Toruner GA, Thakral B. Relapsed NPM1 mutated acute myeloid leukemia with PDGFRA rearrangement. Blood 133(2):181, 2019. PMID: 30630848.
35. Jyonouchi H, Geng L, Toruner GA, Rose S, Bennuri SC, Frye RE. Serum microRNAs in ASD: Association With Monocyte Cytokine Profiles and Mitochondrial Respiration. Front Psychiatry 10:614, 2019. e-Pub 2019. PMID: 31551826.
36. Tang Z, Li Y, Wang W, Yin CC, Tang G, Aung PP, Hu S, Lu X, Toruner GA, Medeiros LJ, Khoury JD. Genomic aberrations involving 12p/ETV6 are highly prevalent in blastic plasmacytoid dendritic cell neoplasms and might represent early clonal events. Leuk Res 73:86-94, 2018. e-Pub 2018. PMID: 30248580.
37. Jyonouchi H, Geng L, Streck DL, Dermody JJ, Toruner GA. MicroRNA expression changes in association with changes in interleukin-1ß/interleukin10 ratios produced by monocytes in autism spectrum disorders: their association with neuropsychiatric symptoms and comorbid conditions (observational study). J Neuroinflammation 14(1):229, 2017. e-Pub 2017. PMID: 29178897.
38. Cogulu O, Schoumans J, Toruner G, Demkow U, Karaca E, Durmaz AA. Laboratory Genetic Testing in Clinical Practice 2016. Biomed Res Int 2017:5798714, 2017. e-Pub 2017. PMID: 28133609.
39. Li MM, Monzon FA, Biegel JA, Jobanputra V, Laffin JJ, Levy B, Leon A, Miron P, Rossi MR, Toruner G, Alvarez K, Doho G, Dougherty MJ, Hu X, Kash S, Streck D, Znoyko I, Hagenkord JM, Wolff DJ. A multicenter, cross-platform clinical validation study of cancer cytogenomic arrays. Cancer Genet 208(11):525-36, 2015. e-Pub 2015. PMID: 26454669.
40. Cogulu O, Schoumans J, Toruner G, Demkow U, Karaca E, Durmaz AA. Laboratory genetic testing in clinical practice 2014. Biomed Res Int 2015:574798, 2015. e-Pub 2015. PMID: 25879026.
41. Saglam O, Dai F, Husain S, Zhan Y, Toruner G, Haines GK. Matricellular protein CCN1 (CYR61) expression is associated with high-grade ductal carcinoma in situ. Hum Pathol 45(6):1269-75, 2014. e-Pub 2014. PMID: 24767859.
42. Saglam O, Husain S, Toruner G. AKT, EGFR, C-ErbB-2, and C-kit expression in uterine carcinosarcoma. Int J Gynecol Pathol 32(5):493-500, 2013. PMID: 23896716.
43. Tang Z, Berlin DS, Toji L, Toruner GA, Beiswanger C, Kulkarni S, Martin CL, Emanuel BS, Christman M, Gerry NP. A dynamic database of microarray-characterized cell lines with various cytogenetic and genomic backgrounds. G3 (Bethesda) 3(7):1143-9, 2013. e-Pub 2013. PMID: 23665875.
44. Fine DH, Toruner GA, Velliyagounder K, Sampathkumar V, Godboley D, Furgang D. A lactotransferrin single nucleotide polymorphism demonstrates biological activity that can reduce susceptibility to caries. Infect Immun 81(5):1596-605, 2013. e-Pub 2013. PMID: 23460521.
45. Cogulu O, Alanay Y, Toruner GA. Laboratory genetic testing in clinical practice. Biomed Res Int 2013:532897, 2013. e-Pub 2013. PMID: 23936813.
46. Toruner GA, Dermody J, Tolias P. Chromosomal microarrays: influential players in the diagnosis of developmental disorders. Per Med 9(2):167-169, 2012. PMID: 29758808.
47. Jyonouchi H, Geng L, Streck DL, Toruner GA. Immunological characterization and transcription profiling of peripheral blood (PB) monocytes in children with autism spectrum disorders (ASD) and specific polysaccharide antibody deficiency (SPAD): case study. J Neuroinflammation 9:4, 2012. e-Pub 2012. PMID: 22226452.
48. Chetcuti A, Aktas S, Mackie N, Ulger C, Toruner G, Alkan M, Catchpoole D. Expression profiling reveals MSX1 and EphB2 expression correlates with the invasion capacity of Wilms tumors. Pediatr Blood Cancer 57(6):950-7, 2011. e-Pub 2011. PMID: 21387540.
49. Jyonouchi H, Geng L, Streck DL, Toruner GA. Children with autism spectrum disorders (ASD) who exhibit chronic gastrointestinal (GI) symptoms and marked fluctuation of behavioral symptoms exhibit distinct innate immune abnormalities and transcriptional profiles of peripheral blood (PB) monocytes. J Neuroimmunol 238(1-2):73-80, 2011. e-Pub 2011. PMID: 21803429.
50. Tolias P, Toruner GA. Clinical utility of DNA testing. Per Med 7(5):461-464, 2010. PMID: 29776239.
51. Zavadil J, Ye H, Liu Z, Wu J, Lee P, Hernando E, Soteropoulos P, Toruner GA, Wei JJ. Profiling and functional analyses of microRNAs and their target gene products in human uterine leiomyomas. PLoS One 5(8):e12362, 2010. e-Pub 2010. PMID: 20808773.
52. Yasar D, Karadogan I, Alanoglu G, Akkaya B, Luleci G, Salim O, Timuragaoglu A, Toruner GA, Berker-Karauzum S. Array comparative genomic hybridization analysis of adult acute leukemia patients. Cancer Genet Cytogenet 197(2):122-9, 2010. PMID: 20193845.
53. Scott SA, Cohen N, Brandt T, Toruner G, Desnick RJ, Edelmann L. Detection of low-level mosaicism and placental mosaicism by oligonucleotide array comparative genomic hybridization. Genet Med 12(2):85-92, 2010. PMID: 20084009.
54. Mittal KR, Chen F, Wei JJ, Rijhvani K, Kurvathi R, Streck D, Dermody J, Toruner GA. Molecular and immunohistochemical evidence for the origin of uterine leiomyosarcomas from associated leiomyoma and symplastic leiomyoma-like areas. Mod Pathol 22(10):1303-11, 2009. e-Pub 2009. PMID: 19633649.
55. Hameed M, Ulger C, Yasar D, Limaye N, Kurvathi R, Streck D, Benevenia J, Patterson F, Dermody JJ, Toruner GA. Genome profiling of chondrosarcoma using oligonucleotide array-based comparative genomic hybridization. Cancer Genet Cytogenet 192(2):56-9, 2009. PMID: 19596254.
56. Toruner GA, Streck DL, Schwalb MN, Dermody JJ. An oligonucleotide based array-CGH system for detection of genome wide copy number changes including subtelomeric regions for genetic evaluation of mental retardation. Am J Med Genet A 143A(8):824-9, 2007. PMID: 17366576.
57. Malfitano AM, Toruner GA, Gazzerro P, Laezza C, Husain S, Eletto D, Orlando P, De Petrocellis L, Terskiy A, Schwalb M, Vitale E, Bifulco M. Arvanil and anandamide up-regulate CD36 expression in human peripheral blood mononuclear cells. Immunol Lett 109(2):145-54, 2007. e-Pub 2007. PMID: 17360047.
58. Onat OE, Tez M, Ozçelik T, Törüner GA. MDM2 T309G polymorphism is associated with bladder cancer. Anticancer Res 26(5A):3473-5, 2006. PMID: 17094469.
59. Ozcelik T, Uz E, Akyerli CB, Bagislar S, Mustafa CA, Gursoy A, Akarsu N, Toruner G, Kamel N, Gullu S. Evidence from autoimmune thyroiditis of skewed X-chromosome inactivation in female predisposition to autoimmunity. Eur J Hum Genet 14(6):791-7, 2006. PMID: 16596118.
60. Toruner GA, Ulger C, Alkan M, Galante AT, Rinaggio J, Wilk R, Tian B, Soteropoulos P, Hameed MR, Schwalb MN, Dermody JJ. Association between gene expression profile and tumor invasion in oral squamous cell carcinoma. Cancer Genet Cytogenet 154(1):27-35, 2004. PMID: 15381369.
61. Ulger C, Toruner GA, Alkan M, Mohammed M, Damani S, Kang J, Galante A, Aviv H, Soteropoulos P, Tolias PP, Schwalb MN, Dermody JJ. Comprehensive genome-wide comparison of DNA and RNA level scan using microarray technology for identification of candidate cancer-related genes in the HL-60 cell line. Cancer Genet Cytogenet 147(1):28-35, 2003. PMID: 14580768.
62. Törüner GA, Uçar A, Tez M, Cetinkaya M, Ozen H, Ozçelik T. P53 codon 72 polymorphism in bladder cancer--no evidence of association with increased risk or invasiveness. Urol Res 29(6):393-5, 2001. PMID: 11828992.
63. Törüner GA, Akyerli C, Uçar A, Aki T, Atsu N, Ozen H, Tez M, Cetinkaya M, Ozçelik T. Polymorphisms of glutathione S-transferase genes (GSTM1, GSTP1 and GSTT1) and bladder cancer susceptibility in the Turkish population. Arch Toxicol 75(8):459-64, 2001. PMID: 11757669.

Invited Articles

1. Toruner GA. Low level ALK FISH Positive Results Should Be Approached with Caution and Confirmed by an Orthogonal Method. Transl Lung Cancer Res 12(7):1361-1363, 2023. e-Pub 2023. PMID: 37577303.

Other Articles

1. Dimopoulos YP, Thakral B, Lin P, Toruner G, Zuo Z, Medeiros LJ, Leventaki V From the archives of MD Anderson Cancer Center: Composite mantle cell lymphoma and lymphoplasmacytic lymphoma involving bone marrow at presentation. Ann Diagn Pathol 73(None):152372, 2024. PMID: 39208652.
2. Sameeta F, Fang H, Wang W, Tang Z, Wang SA, Toruner GA, Parisi X, Khoury JD, Issa G, Garcia-Manero G, Medeiros LJ, Tang G, Loghavi S Myeloid neoplasm with <10% blasts and t(3;5)(q25.1;q34)/NPM::MLF1: A classification dilemma. Am J Hematol. PMID: 38440855.
3. Quesada AE, Hu S, Li S, Toruner GA, Wei Q, Loghavi S, Ok CY, Jain P, Thakral B, Nwogbo OV, Kim D, Iyer SP, You MJ, Medeiros LJ, Tang G Optical genomic mapping is a helpful tool for detecting CCND1 rearrangements in CD5-negative small B-cell lymphoma: Two cases of leukemic non-nodal mantle cell lymphoma. Hum Pathol 144:71-76, 2024. PMID: 38301962.
4. Vanjari N, Tang G, Toruner GA, Wang W, Thakral B, Zhao M, Dave BJ, Khoury JD, Medeiros LJ, Tang Z Optical Genome Mapping Helps to Identify BCR::JAK2 Rearrangement Arising from Cryptic Complex Chromosomal Aberrations: A Case Report and Literature Review. Genes (Basel) 14(12), 2023. PMID: 38137010.
5. Wang L, Wang W, Beird HC, Cheng X, Fang H, Tang G, Toruner GA, Yin CC, You MJ, Issa GC, Borthakur G, Peng G, Khoury JD, Medeiros LJ, Tang Z PPP1R7 Is a Novel Translocation Partner of CBFB via t(2;16)(q37;q22) in Acute Myeloid Leukemia. Genes (Basel) 13(8), 2022. PMID: 36011278.
6. Grant BJ, Tang Z, Toruner GA, Mahdi A, Bigham L, Dong J, Musunuru T, Mallick J, Lyapichev KA A rare case of complex variant translocation of t(9;22;16)(q34;q11.2;q24) in a newly diagnosed patient with chronic myeloid leukemia. Leuk Res Rep 18:100351, 2022. PMID: 36176359.
7. Tang Z, Toruner GA, Tang G, Yin CC, Wang W, Hu S, Thakral B, Wang SA, Miranda RN, Khoury JD, Medeiros LJ Correction: Chronic myeloid leukemia with insertion-derived BCR-ABL1 fusion: redefining complex chromosomal abnormalities by correlation of FISH and karyotype predicts prognosis. Mod Pathol 33(10):2088, 2020. PMID: 32737448.
8. Durmaz AA, Karaca E, Demkow U, Toruner G, Schoumans J, Cogulu O Evolution of genetic techniques: past, present, and beyond. Biomed Res Int 2015:461524, 2015. PMID: 25874212.
9. Bagci G, Cetin GO, Semerci N, Toruner GA, Cinbis M Terminal 14q deletion with unbalanced t(Y;14)(q12;q32) translocation. Clin Dysmorphol 21(1):37-41, 2012. PMID: 22143350.
10. Toruner GA, Kurvathi R, Sugalski R, Shulman L, Twersky S, Pearson PG, Tozzi R, Schwalb MN, Wallerstein R Copy number variations in three children with sudden infant death. Clin Genet 76(1):63-8, 2009. PMID: 19659761.
11. Jyonouchi H, Geng L, Törüner GA, Vinekar K, Feng D, Fitzgerald-Bocarsly P Monozygous twins with a microdeletion syndrome involving BTK, DDP1, and two other genes; evidence of intact dendritic cell development and TLR responses. Eur J Pediatr 167(3):317-21, 2008. PMID: 17520285.
12. Wallerstein RJ, Brooks SS, Streck DL, Kurvathi R, Toruner GA Exclusion of APC and VHL gene deletions by array-based comparative hybridization in two patients with microscopically visible chromosomal aberrations. Cancer Genet Cytogenet 178(2):151-4, 2007. PMID: 17954272.
13. Zherebtsov MM, Klein RT, Aviv H, Toruner GA, Hanna NN, Brooks SS Further delineation of interstitial chromosome 6 deletion syndrome and review of the literature. Clin Dysmorphol 16(3):135-40, 2007. PMID: 17551325.
14. Topçu M, Akyerli C, Sayi A, Törüner GA, Koçoglu SR, Cimbis M, Ozçelik T Somatic mosaicism for a MECP2 mutation associated with classic Rett syndrome in a boy. Eur J Hum Genet 10(1):77-81, 2002. PMID: 11896459.

Editorials

1. Toruner GA, Tolias P. Research Highlights: Copy-number variation in patients with developmental delay and autistic spectrum disorders underscored by targeted exonic array CGH. Personalized Medicine 10(1):17-18, 2013. PMID: 29783470.
2. Toruner GA, Demody J, Tolias P. Chromosomal microarrays: influential players in the diagnosis of developmental disorders By. Personalized Medicine 9(2):167-169, 2012. PMID: None.
3. Tolias P, Toruner GA. Clinical utility of DNA testing. Personalized Medicine 7(5):461-464, 2010. PMID: None.

Abstracts

1. Tang Z, Tang G, Toruner GA, Yang S, Wang W, Fang H, El Achi H, Thakral B, Xu J, Yin CC, You J, Miranda R, Khoury JD, Medeiros LJ. Acquired 3q26.2 Aberrations/MECOM Rearrangements Are Common in Donor Cell Leukemia. Laboratory Investigation-USCAP 2023, 2023. PMID: None.
2. Nahmod K, Tang Z, Lin P, Toruner GA, Li S, Xu J, Hu S, Medeiros LJ, Tang G. Cytogenetic Clonal Evolution in Plasma Cell Neoplasms. Modern Pathology- USCAP 2023, 2023. PMID: None.
3. Yang RK, Alvarez H, Roy-Chowdhuri S, Rashid A, Chen H Ballester LY, Routbort M, Patel KP, Luthra R, Medeiros LJ, Toruner GA. Co-occurrence of Microsatellite Instability (MSI) and High Tumor Mutational Burden (TMB) by Next Generation Sequencing is Concordant with Loss of Mismatch Repair Proteins by Immunohistochemistry. Genetics in Medicine- ACMG 2023, 2023. PMID: None.
4. Esplen H, Yang RK, Kalia A, Tang Z, Tang G, Medeiros LJ, Toruner GA. Recurrent Somatic Copy Number Alterations and Their Association with Gene Expression Levels on Cancer Genes in Ovarian Serous Cystadenocarcinoma. Genetics in Medicine- ACMG 2023, 2023. PMID: None.
5. Diks J, Tang Z, Altan M, Chen H, Rashid A, Yang R, Routbort M, Patel KP, Toruner GA, Tang G, Roy-Chowdhuri S. Clinically Actionable Gene Fusion Detection by Next-Generation Sequencing-Based RNA Sequencing in Non-Small Cell Lung Cancer Cytology Specimens: A Single Center Experience with Comparison to Fluorescence in Situ Hybridization. Laboratory Investigation-USCAP 2023, 2023. PMID: None.
6. Evans, Khoury M, DiNardo J, Garcia-Manero C, Yang G, Loghavi H, Montalban-Bravo S, Patel G, Quesada K, Konoplev A, Garces S, Toruner S, Bueso-Ramos G, Medeiros C, Kanagal-Shamanna LJ, R. Bone Marrow Pathologic Abnormalities in Myelodysplastic Syndrome (MDS) Patients with Underlying TERT/TERC Germline Alterations. Laboratory Investigation-USCAP 2022 35(2):945-946, 2022. PMID: None.
7. Tang Z, Yin W, Hong L, Vokes N, Tang G, Toruner GA, Chen H, Chowdhuri SR, Zhang J, Medeiros LJ. Clinical Implication of Persistent Positive ALK Status in Lung Cancer: Analysis of 18 cases. Journal of Molecular Diagnostics, AMP 2021. Virtual 23(11), 2021. PMID: None.
8. Toruner G, Thakral B, Tang Z, Tang G, Medeiros LJ, Oran B. Clonal Cytogenetic Abnormalities in Donor-Derived Cells after Sex-Mismatched Allogeneic Stem Cell Transplantation. Journal of Molecular Diagnostics, AMP 2021. Virtual 23(11), 2021. PMID: None.
9. Tang Z, Tang G, Chen H, Toruner GA, Medeiros LJ. Fluorescence In Situ Hybridization As The Gold Standard For ALK Testing In Lung Cancer: Analysis Of 168 Positive Cases. ACMG, 2019 Meeting , Seattle, WA, 2019. PMID: None.
10. Tang Z, Tang G, Hu S, Patel KP, Yin CC, Wang W, Lin P, Toruner GA, Ok CY, Gu J, Lu X, Khoury JD, Medeiros LJ. Chromosomal Aberrations Causing MECOM Rearrangement In Myeloid Malignancies: Analysis Of 129 Cases. ACMG, 2019 Meeting , Seattle, WA, 2019. PMID: None.
11. Toruner GA, Tang Z, Tang G. Optical mapping for chromosomal abnormalities: A pilot feasibility study for clinical use. ASHG 2019. Houston, TX, 2019. PMID: None.
12. Tang G, Hu S, Tang Z, Toruner G, Medeiros LJ, Xie W. T(3;8)(q26.2;q24) is commonly associated with therapy-related myeloid neoplasms and involves MECOM/MYC rearrangement. ASHG 2018 meeting, San Diego, CA, 2018. PMID: None.
13. Tang Z, Wang W, Tang G, Pemmaraju N, Hu S, Yin CC, Konopleva M, Toruner G, Medeiros LJ. ETV6 deletion as a potential biomarker for BPDCN. ASHG 2018 meeting, San Diego, CA, 2018. PMID: None.