Goldy C. George, Ph.D.
Department of Symptom Research, Division of Internal Medicine
Present Title & Affiliation
Primary Appointment
Assistant Professor, Department of Symptom Research, Division of Internal Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX
Research Interests
Symptoms and health-related quality of life Patient-reported outcomes Outcomes reporting and prediction in oncology clinical trials Adolescent and young adult cancer Diet during cancer treatment and survivorship
Education & Training
Degree-Granting Education
| 2004 | The University of Texas at Austin, Austin, TX, USA, PHD, Nutritional Sciences |
| 1996 | University of Madras, Chennai, IND, MS, Foods and Nutrition |
| 1994 | University of Madras, Chennai, IND, BS, Nutrition and Dietetics |
Postgraduate Training
| 2004-2007 | NCI R25 Funded Postdoctoral Fellowship, Cancer Prevention and Control, The University of Texas School of Public Health, Houston, TX |
Experience & Service
Academic Appointments
Instructor, Department of Symptom Research, Division of Internal Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, 2016 - 2020
Other Appointments/Responsibilities
Senior Research Scientist, Department of Investigational Cancer Therapeutics, Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, 2014 - 2015
Clinical Research Scientist/Analyst, Department of Investigational Cancer Therapeutics, Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, 2011 - 2014
Institutional Committee Activities
Chair, Division of Internal Medicine Research Grand Rounds Subcommittee, The University of Texas MD Anderson Cancer Center, 2024 - 2025
Vice-Chair, Division of Internal Medicine Research Grand Rounds Subcommittee, The University of Texas MD Anderson Cancer Center, 2023 - 2024
Honors & Awards
| 2023 | Competitively selected for the NCI Awardee Skills Development Consortium Academic Career Skills Course: "Leadership, Collaboration and Resilience", NCI and Dana Farber Cancer Institute, Harvard University |
| 2022 | Competitively selected for the NCI Awardee Skills Development Consortium Short Course: “The Cell & Gene Therapy Toolkit for Junior Faculty”, NCI and Children's Hospital of Philadelphia, University of Pennsylvania |
| 2015 | Hawn Foundation Fellowship, Hawn Foundation and Department of Symptom Research, The University of Texas MD Anderson Cancer Center |
| 2005 | L'Oreal USA Women in Science Award, Finalist with Honorable Mention, L'Oreal USA |
| 2004 | 4.0 GPA, PhD, Nutritional Sciences, The University of Texas at Austin |
| 2002 | Outstanding Student Research Award, Society for Nutrition Education |
| 2001 | David Bruton Jr. University Continuing Fellowship, The University of Texas at Austin |
| 2000 | Phi Kappa Phi, National Honor Society |
Selected Publications
Peer-Reviewed Articles
- George GC, Andersen C, Tang X, Rodriguez E, Jafry M, Swartz MC, Ahmed S, Barcenas CH, Livingston JA, Roth ME, Hildebrandt MAT.. Patient-reported quality of life at diagnosis in adolescent and young adults with cancer. J Natl Compr Canc Netw 22(6):1-8, 2024. PMID: 38996438.
- Mendoza TR, Hong DS, Peterson CB, Stephen B, Dumbrava E, Pant S, Tsimberidou AM, Yap TA, Sheshadri A, Altan M, George G, Castillo L, Rodriguez E, Gong J, Subbiah V, Janku F, Fu S, Piha-Paul SA, Ahnert JR, Karp DD, Cleeland C, Meric-Bernstam F, Naing A. Patient-reported symptom burden in patients with rare cancers receiving pembrolizumab in a phase II clinical trial. Sci Rep 12(1):14367, 2022. e-Pub 2022. PMID: 35999229.
- Son J, George GC, Nardo M, Krause KJ, Jazaeri AA, Biter AB, Hong DS. Adoptive cell therapy in gynecologic cancers: A systematic review and meta-analysis. Gynecol Oncol 165(3):664-670, 2022. e-Pub 2022. PMID: 35400527.
- Huey RW, George GC, Phillips P, White R, Fu S, Janku F, Karp DD, Naing A, Piha-Paul S, Subbiah V, Tsimberidou AM, Pant S, Yap TA, Rodon J, Meric-Bernstam F, Shih YT, Hong DS. Patient-Reported Out-of-Pocket Costs and Financial Toxicity During Early-Phase Oncology Clinical Trials. Oncologist 26(7):588-596, 2021. e-Pub 2021. PMID: 33783054.
- Mendoza T, Sheshadri A, Altan M, Hess K, George G, Stephen B, Castillo L, Rodriguez E, Gong J, Peterson C, Rodon Ahnert J, Fu S, Piha-Paul SA, Pant S, Dumbrava E, Yap TA, Janku F, Tsimberidou AM, Subbiah V, Karp DD, Zarifa A, McQuinn LM, Cleeland C, Hong DS, Naing A. Evaluating the psychometric properties of the Immunotherapy module of the MD Anderson Symptom Inventory. J Immunother Cancer 8(2), 2020. PMID: 33097611.
- George GC, Mendoza TR, Iwuanyanwu EC, Manandhar M, Afshar SF, Piha-Paul SA, Tsimberidou A, Naing A, Cleeland CS, Hong DS. Factors affecting symptom presentation in an early-phase clinical trials clinic patient population. Invest New Drugs 38(4):1166-1174, 2020. e-Pub 2019. PMID: 31761957.
- George GC, Barata PC, Campbell A, Chen A, Cortes JE, Hyman DM, Jones L, Karagiannis T, Klaar S, Le-Rademacher JG, LoRusso P, Mandrekar SJ, Merino DM, Minasian LM, Mitchell SA, Montez S, O'Connor DJ, Pettit S, Silk E, Sloan JA, Stewart M, Takimoto CH, Wong GY, Yap TA, Cleeland CS, Hong DS. Improving attribution of adverse events in oncology clinical trials. Cancer Treat Rev 76:33-40, 2019. e-Pub 2019. PMID: 31108240.
- George GC, Iwuanyanwu EC, Buford AS, Piha-Paul SA, Subbiah V, Fu S, Karp DD, Pant S, Hinojosa CO, Hess KR, Cleeland CS, Bernstam EV, Meric-Bernstam F, Hong DS. Cancer-related Internet use and its association with patient decision making and trust in physicians among patients in an early drug development clinic: a questionnaire-based cross-sectional observational study. J Med Internet Res 21(3):e10348, 2019. e-Pub 2019. PMID: 30869638.
- George GC, Buford A, Hess K, Piha-Paul SA, Zinner R, Subbiah V, Hinojosa C, Cleeland CS, Meric-Bernstam F, Bernstam EV, Hong DS. Cancer-related Internet use and online social networking among patients in an early-phase clinical trials clinic at a comprehensive cancer center. JCO Clin Cancer Inform 2:1-14, 2018. PMID: 30652565.
- Sanjeevi N, Freeland-Graves J, George GC. Relative validity and reliability of a 1-week, semiquantitative food frequency questionnaire for women participating in the Supplemental Nutrition Assistance Program. J Acad Nutr Diet 117(12):1972-1982.e2, 2017. e-Pub 2017. PMID: 28669810.
- Kehl KL, Fullmer CP, Fu S, George GC, Hess KR, Janku F, Karp DD, Kato S, Kizer CK, Kurzrock R, Naing A, Pant S, Piha-Paul SA, Subbiah V, Tsimberidou AM, Hong DS. Insurance clearance for early-phase oncology clinical trials following the Affordable Care Act. Clin Cancer Res 23:4155-4162, 2017. e-Pub 2017. PMID: 28729355.
- George GC, Iwuanyanwu EC, Anderson KO, Yusuf A, Zinner RG, Piha-Paul SA, Tsimberidou AM, Naing A, Fu S, Janku F, Subbiah V, Cleeland CS, Mendoza TR, Hong DS. Sleep quality and its association with fatigue, symptom burden, and mood in patients with advanced cancer in a clinic for early-phase oncology clinical trials. Cancer 122(21):3401-3409, 2016. e-Pub 2016. PMID: 27412379.
- Hong DS, Kurzrock R, Falchook GS, Andresen C, Kwak J, Ren M, Xu L, George GC, Kim KB, Nguyen LM, O'Brien JP, Nemunaitis J. Phase 1b study of lenvatinib (E7080) in combination with temozolomide for treatment of advanced melanoma. Oncotarget 6(40):43127-34, 2015. PMID: 26503473.
- Hong DS, Kurzrock R, Wheler JJ, Naing A, Falchook GS, Fu S, Kim KB, Davies MA, Nguyen LM, George GC, Xu L, Shumaker R, Ren M, Mink J, Bedell C, Andresen C, Sachdev P, O'Brien JP, Nemunaitis J. Phase I dose-escalation study of the multikinase inhibitor lenvatinib in patients with advanced solid tumors and in an expanded cohort of patients with melanoma. Clin Cancer Res 21(21):4801-10, 2015. e-Pub 2015. PMID: 26169970.
- Henary H, George GC, Wheler J, Naing A, Piha-Paul S, Fu S, Mistry R, Zinner R, Kurzrock R, Hong DS. A phase 1 study of intermittently administered pazopanib in combination with continuous daily dosing of lapatinib in patients with solid tumors. Cancer Chemother Pharmacol 76(3):597-603, 2015. e-Pub 2015. PMID: 26210681.
- Vishnoi M, Peddibhotla S, Yin W, T Scamardo A, George GC, Hong DS, Marchetti D. The isolation and characterization of CTC subsets related to breast cancer dormancy. Sci Rep 5:17533, 2015. e-Pub 2015. PMID: 26631983.
- Liu X, George GC, Tsimberidou AM, Naing A, Wheler JJ, Kopetz S, Fu S, Piha-Paul SA, Eng C, Falchook GS, Janku F, Garrett C, Karp D, Kurzrock R, Zinner R, Raghav K, Subbiah V, Hess K, Meric-Bernstam F, Hong DS, Overman MJ. Retreatment with anti-EGFR based therapies in metastatic colorectal cancer: impact of intervening time interval and prior anti-EGFR response. BMC Cancer 15:713, 2015. e-Pub 2015. PMID: 26474549.
- Hong DS, Garrido-Laguna I, Ekmekcioglu S, Falchook GS, Naing A, Wheler JJ, Fu S, Moulder SL, Piha-Paul S, Tsimberidou AM, Wen Y, Culotta KS, Anderes K, Davis DW, Liu W, George GC, Camacho LH, Percy Ivy S, Kurzrock R. Dual inhibition of the vascular endothelial growth factor pathway: a phase 1 trial evaluating bevacizumab and AZD2171 (cediranib) in patients with advanced solid tumors. Cancer 120(14):2164-73, 2014. e-Pub 2014. PMID: 24752867.
- Hong DS, Choe JH, Naing A, Wheler JJ, Falchook GS, Piha-Paul S, Moulder SL, George GC, Choe JM, Strauss LC, Gallick GE, Kurzrock R. A phase 1 study of gemcitabine combined with dasatinib in patients with advanced solid tumors. Invest New Drugs 31(4):918-26, 2013. e-Pub 2012. PMID: 23179336.
- Henary H, Hong DS, Falchook GS, Tsimberidou A, George GC, Wen S, Wheler J, Fu S, Naing A, Piha-Paul S, Janku F, Kim KB, Hwu P, Kurzrock R. Melanoma patients in a phase I clinic: molecular aberrations, targeted therapy and outcomes. Ann Oncol 24(8):2158-65, 2013. e-Pub 2013. PMID: 23576709.
- Hong DS, Banerji U, Tavana B, George GC, Aaron J, Kurzrock R. Targeting the molecular chaperone heat shock protein 90 (HSP90): lessons learned and future directions. Cancer Treat Rev 39(4):375-87, 2013. e-Pub 2012. PMID: 23199899.
- Hong DS, George GC, Iwuanyanwu EC, Tavana B, Falchook GS, Piha-Paul SA, Wheler JJ, Mistry RH, Lei X, Kurzrock R. Factors related to biopsy willingness in patients with advanced cancer in a phase 1 clinic for molecularly targeted therapy. J Cancer Res Clin Oncol 139(6):963-70, 2013. e-Pub 2013. PMID: 23455881.
- Hong DS, Bowles DW, Falchook GS, Messersmith WA, George GC, O'Bryant CL, Vo AC, Klucher K, Herbst RS, Eckhardt SG, Peterson S, Hausman DF, Kurzrock R, Jimeno A. A multicenter phase I trial of PX-866, an oral irreversible phosphatidylinositol 3-kinase inhibitor, in patients with advanced solid tumors. Clin Cancer Res 18(15):4173-82, 2012. e-Pub 2012. PMID: 22693357.
- Schiefelbein EL, Mirchandani GG, George GC, Becker EA, Castrucci BC, Hoelscher DM. Association between depressed mood and perceived weight in middle and high school age students: Texas 2004-2005. Matern Child Health J 16(1):169-76, 2012. PMID: 21165762.
- George GC, Springer AE, Forman MR, Hoelscher DM. Associations among dietary supplement use and dietary and activity behaviors by sex and race/ethnicity in a representative multiethnic sample of 11th-grade students in Texas. J Am Diet Assoc 111(3):385-93, 2011. PMID: 21338737.
- George GC, Hoelscher DM, Nicklas TA, Kelder SH. Diet- and body size-related attitudes and behaviors associated with vitamin supplement use in a representative sample of fourth-grade students in Texas. J Nutr Educ Behav 41(2):95-102, 2009. PMID: 19304254.
- Penkilo M, George GC, Hoelscher DM. Reproducibility of the School-Based Nutrition Monitoring Questionnaire among fourth-grade students in Texas. J Nutr Educ Behav 40(1):20-7, 2008. PMID: 18174100.
- George GC, Hanss-Nuss H, Milani TJ, Freeland-Graves JH. Food choices of low-income women during pregnancy and postpartum. J Am Diet Assoc 105(6):899-907, 2005. PMID: 15942539.
- George GC, Milani TJ, Hanss-Nuss H, Freeland-Graves JH. Compliance with dietary guidelines and relationship to psychosocial factors in low-income women in late postpartum. J Am Diet Assoc 105(6):916-26, 2005. PMID: 15942541.
- Klohe DM, Clarke KK, George GC, Milani TJ, Hanss-Nuss H, Freeland-Graves J. Relative validity and reliability of a food frequency questionnaire for a triethnic population of 1-year-old to 3-year-old children from low-income families. J Am Diet Assoc 105(5):727-34, 2005. PMID: 15883549.
- Walker LO, Freeland-Graves JH, Milani T, Hanss-Nuss H, George G, Sterling BS, Kim M, Timmerman GM, Wilkinson S, Arheart KL, Stuifbergen A. Weight and behavioral and psychosocial factors among ethnically diverse, low-income women after childbirth: I. Methods and context. Women Health 40(2):1-17, 2004. PMID: 15778135.
- Walker L, Freeland-Graves JH, Milani T, George G, Hanss-Nuss H, Kim M, Sterling BS, Timmerman GM, Wilkinson S, Arheart KL, Stuifbergen A. Weight and behavioral and psychosocial factors among ethnically diverse, low-income women after childbirth: II. Trends and correlates. Women Health 40(2):19-34, 2004. PMID: 15778136.
Other Articles
- Sucholeiki RL, Propst CL, Hong DS, George GC. Intermittent fasting and its impact on toxicities, symptoms and quality of life in patients on active cancer treatment. Cancer Treat Rev 126:1-14, 2024. PMID: 38574507.
- Kim AJ, Hong DS, George GC Dietary influences on symptomatic and non-symptomatic toxicities during cancer treatment: A narrative review. Cancer Treat Rev 108:102408, 2022. PMID: 35623220.
- Kim AJ, Hong DS, George GC Diet-related interventions for cancer-associated cachexia. J Cancer Res Clin Oncol 147(5):1443-1450, 2021. PMID: 33718995.
Grant & Contract Support
| Title: | Use of Patient-Reported Outcomes in Understanding Symptomatic Adverse Events in Early-Phase Trials of Combination Treatments that Include Immune Checkpoint Inhibitors and Targeted Therapy |
| Funding Source: | NIH/NCI |
| Role: | Multi Principal Investigator (MPI) |
Patient Reviews
CV information above last modified September 02, 2024