Guofan Xu, M.B.B.S., Ph.D.
Department of Nuclear Medicine, Division of Diagnostic Imaging
Present Title & Affiliation
Primary Appointment
Associate Professor, Department of Nuclear Medicine, Division of Diagnostic Imaging, The University of Texas MD Anderson Cancer Center, Houston, TX
Research Interests
Development of multi-modal imaging techniques with pre-clinical and clinical molecular tracers for oncological imaging and targeted radiotherapy.
Education & Training
Degree-Granting Education
| 2006 | Medical College of Wisconsin, Milwaukee, WI, USA, PHD, Magnetic Resonance Imaging Program |
| 1998 | Sun Yat-Sen University of Medical Sciences, Guangzhou, CHN, MBBS, Medicine |
Board Certifications
| 2014 | America Board of Nuclear Medicine |
Experience & Service
Academic Appointments
Assistant Professor, Department of Nuclear Medicine, Division of Diagnostic Imaging, The University of Texas MD Anderson Cancer Center, Houston, TX, 2018 - 2023
Staff Physician, Department of Nuclear Medicine, Division of Diagnostic Imaging, San Jose Medical Center, San Jose, CA, 2015 - 2018
Fellow, Department of Nuclear Medicine, Division of Diagnostic Imaging, Stanford Hospital and Clinics, Stanford, CA, 2014 - 2015
Resident, Department of Nuclear Medicine, Division of Diagnostic Imaging, University Wisconsin Hospital and Clinic, Madison, WI, 2011 - 2014
Research Scientist, Department of Nuclear Medicine, Division of Diagnostic Imaging, University of Wisconsin School of Medicine and Public Health, Madison, WI, 2008 - 2011
Research Associate (post-doc fellow), Department of Nuclear Medicine, Division of Diagnostic Imaging, University of Wisconsin School of Medicine and Public Health, Madison, WI, 2006 - 2008
Resident (Radiology), Department of Nuclear Medicine, Division of Diagnostic Imaging, Sun Yat-Sen University of Medical Sciences, Guangzhou, 1998 - 2001
Honors & Awards
| 2012 | Society of Nuclear Medicine and Molecular Imaging Annual Meeting young investigator award finalist |
| 2010 | Alzheimer's Association New Investigator Award |
| 2008 | International Alzheimer's Associate Travel Fellowship Award |
| 2006 | International Society for Magnetic Resonance in Medicine Student Travel Awards |
| 2005 | International Society for Magnetic Resonance in Medicine Student Travel Awards |
| 2003 | International Society for Magnetic Resonance in Medicine Student Travel Awards |
Professional Memberships
Selected Publications
Peer-Reviewed Articles
- Minamimoto R, Xu G, Jamali M, Holley D, Barkhodari A, Zaharchuk G, Iagaru A. Semiquantitative Assessment of 18F-FDG Uptake in the Normal Skeleton: Comparison Between PET/CT and Time-of-Flight Simultaneous PET/MRI. AJR Am J Roentgenol 209(5):1136-1142, 2017. e-Pub 2017. PMID: 28777652.
- Douglas D, Goubran M, Wilson E, Xu G, Tripathi P, Holley D, Chao S, Wintermark M, Quon A, Zeineh M, Vasanawala M, Zaharchuk G. Correlation between arterial spin labeling MRI and dynamic FDG on PET-MR in Alzheimer's disease and non-Alzhiemer's disease patients. EJNMMI Phys 2(Suppl 1):A83, 2015. PMID: 26956345.
- Hiniker SM, Pollom EL, Khodadoust MS, Kozak MM, Xu G, Quon A, Advani RH, Hoppe RT. Value of surveillance studies for patients with stage I to II diffuse large B-cell lymphoma in the rituximab era. Int J Radiat Oncol Biol Phys 92(1):99-106, 2015. PMID: 25863757.
- Ly M, Canu E, Xu G, Oh J, McLaren DG, Dowling NM, Alexander AL, Sager MA, Johnson SC, Bendlin BB. Midlife measurements of white matter microstructure predict subsequent regional white matter atrophy in healthy adults. Hum Brain Mapp 35(5):2044-54, 2014. e-Pub 2013. PMID: 23861348.
- Okonkwo OC, Xu G, Oh JM, Dowling NM, Carlsson CM, Gallagher CL, Birdsill AC, Palotti M, Wharton W, Hermann BP, LaRue A, Bendlin BB, Rowley HA, Asthana S, Sager MA, Johnson SC. Cerebral blood flow is diminished in asymptomatic middle-aged adults with maternal history of Alzheimer's disease. Cereb Cortex 24(4):978-88, 2014. e-Pub 2012. PMID: 23236200.
- Willette AA, Xu G, Johnson SC, Birdsill AC, Jonaitis EM, Sager MA, Hermann BP, La Rue A, Asthana S, Bendlin BB. Insulin resistance, brain atrophy, and cognitive performance in late middle-aged adults. Diabetes Care 36(2):443-9, 2013. e-Pub 2012. PMID: 23069842.
- Carlsson CM, Xu G, Wen Z, Barnet JH, Blazel HM, Chappell RJ, Stein JH, Asthana S, Sager MA, Alsop DC, Rowley HA, Fain SB, Johnson SC. Effects of atorvastatin on cerebral blood flow in middle-aged adults at risk for Alzheimer's disease: a pilot study. Curr Alzheimer Res 9(8):990-7, 2012. PMID: 22175654.
- McLaren DG, Ries ML, Xu G, Johnson SC. A generalized form of context-dependent psychophysiological interactions (gPPI): a comparison to standard approaches. Neuroimage 61(4):1277-86, 2012. e-Pub 2012. PMID: 22484411.
- Prabhakaran V, Nair VA, Austin BP, La C, Gallagher TA, Wu Y, McLaren DG, Xu G, Turski P, Rowley H. Current status and future perspectives of magnetic resonance high-field imaging: a summary. Neuroimaging Clin N Am 22(2):373-97, xii, 2012. PMID: 22548938.
- Johnson SC, La Rue A, Hermann BP, Xu G, Koscik RL, Jonaitis EM, Bendlin BB, Hogan KJ, Roses AD, Saunders AM, Lutz MW, Asthana S, Green RC, Sager MA. The effect of TOMM40 poly-T length on gray matter volume and cognition in middle-aged persons with APOE ε3/ε3 genotype. Alzheimers Dement 7(4):456-65, 2011. PMID: 21784354.
- Hinrichs C, Singh V, Xu G, Johnson SC, Alzheimers Disease Neuroimaging Initiative. Predictive markers for AD in a multi-modality framework: an analysis of MCI progression in the ADNI population. Neuroimage 55(2):574-89, 2011. e-Pub 2010. PMID: 21146621.
- Gallagher CL, Oakes TR, Johnson SC, Chung MK, Holden JE, Bendlin BB, McLaren DG, Xu G, Nickles RJ, Pyzalski R, DeJesus O, Brown WD. Rate of 6-[18F]fluorodopa uptake decline in striatal subregions in Parkinson's disease. Mov Disord 26(4):614-20, 2011. e-Pub 2011. PMID: 21449008.
- Austin BP, Nair VA, Meier TB, Xu G, Rowley HA, Carlsson CM, Johnson SC, Prabhakaran V. Effects of hypoperfusion in Alzheimer's disease. J Alzheimers Dis 26 Suppl 3:123-33, 2011. PMID: 21971457.
- Kastman EK, Willette AA, Coe CL, Bendlin BB, Kosmatka KJ, McLaren DG, Xu G, Canu E, Field AS, Alexander AL, Voytko ML, Beasley TM, Colman RJ, Weindruch RH, Johnson SC. A calorie-restricted diet decreases brain iron accumulation and preserves motor performance in old rhesus monkeys. J Neurosci 30(23):7940-7, 2010. PMID: 20534842.
- Xu G, Rowley HA, Wu G, Alsop DC, Shankaranarayanan A, Dowling M, Christian BT, Oakes TR, Johnson SC. Reliability and precision of pseudo-continuous arterial spin labeling perfusion MRI on 3.0 T and comparison with 15O-water PET in elderly subjects at risk for Alzheimer's disease. NMR Biomed 23(3):286-93, 2010. PMID: 19953503.
- Hinrichs C, Singh V, Mukherjee L, Xu G, Chung MK, Johnson SC, Alzheimer's Disease Neuroimaging Initiative. Spatially augmented LPboosting for AD classification with evaluations on the ADNI dataset. Neuroimage 48(1):138-49, 2009. e-Pub 2009. PMID: 19481161.
- Xu G, McLaren DG, Ries ML, Fitzgerald ME, Bendlin BB, Rowley HA, Sager MA, Atwood C, Asthana S, Johnson SC. The influence of parental history of Alzheimer's disease and apolipoprotein E epsilon4 on the BOLD signal during recognition memory. Brain 132(Pt 2):383-91, 2009. e-Pub 2008. PMID: 18829694.
- Hinrichs C, Singh V, Xu G, Johnson S. MKL for robust multi-modality AD classification. Med Image Comput Comput Assist Interv 12(Pt 2):786-94, 2009. PMID: 20426183.
- Xu G, Fitzgerald ME, Wen Z, Fain SB, Alsop DC, Carroll T, Ries ML, Rowley HA, Sager MA, Asthana S, Johnson SC, Carlsson CM. Atorvastatin therapy is associated with greater and faster cerebral hemodynamic response. Brain Imaging Behav 2(2):94, 2008. PMID: 20157644.
- Xu Y, Xu G, Wu G, Antuono P, Rowe DB, Li SJ. The phase shift index for marking functional asynchrony in Alzheimer's disease patients using fMRI. Magn Reson Imaging 26(3):379-92, 2008. PMID: 18164158.
- Xu Y, Wu G, Rowe DB, Ma Y, Zhang R, Xu G, Li SJ. COmplex-Model-Based Estimation of thermal noise for fMRI data in the presence of artifacts. Magn Reson Imaging 25(7):1079-88, 2007. e-Pub 2007. PMID: 17707170.
- Xu G, Xu Y, Wu G, Antuono PG, Hammeke TA, Li SJ. Task-modulation of functional synchrony between spontaneous low-frequency oscillations in the human brain detected by fMRI. Magn Reson Med 56(1):41-50, 2006. PMID: 16767759.
- Yang Z, Xu G. Craniopagus twins. Chin Med J (Engl) 115(8):1262-3, 2002. PMID: 12515280.
Patient Reviews
CV information above last modified October 19, 2023