Guofan Xu, M.B.B.S., Ph.D.

Peer-Reviewed Articles

1. Tewari SO, Tamirisa N, Xu G, Lu Y. Vapocoolant Analgesia for Breast Lymphoscintigraphy: A Prospective Clinical Trial. J Nucl Med Technol 52(2):104-106, 2024. e-Pub 2024. PMID: 37963780.
2. Lu Y, Wilson ZJ, Xu G, Xu Z, Pan T, Wei P. Diagnostic Performance of PSMA-Based 18F-DCFPyL PET/CT in Prostate Cancer Patients After Definitive Treatment With PSA Level =0.2 ng/mL. Clin Nucl Med 48(12):1021-1027, 2023. e-Pub 2023. PMID: 37801580.
3. Thomas AR, Eyada M, Kono M, Varatharajalu K, Lu Y, Xu G, Panneerselvam K, Shatila M, Altan M, Wang J, Thompson JA, Zhang HC, Khan MA, Raju GS, Thomas AS, Wang Y. Characteristics, treatment, and outcome of diverticulitis after immune checkpoint inhibitor treatment in patients with malignancies. J Cancer Res Clin Oncol 149(8):4805-4816, 2023. e-Pub 2023. PMID: 36242603.
4. Strati P, Pasvolsky O, Feng L, Xu G, Tewari SO, Varghese J, Ow K, Santiago M, Al Zaki A, Jallouk A, Neelapu SS, Kebriaei P, Shpall EJ, Ahmed S. ASCT vs CART for patients with relapsed LBCL in PR: role of TMTV. Blood Adv 7(11):2586-2589, 2023. e-Pub 2023. PMID: 36745104.
5. Lu, Y, Xu, G, Jimenez, C. Proposed MIBG Scan-Based Tumor Response Criteria of High-Specific-Activity 131I-MIBG Therapy in Metastatic Pheochromocytoma/Paraganglioma. Clinical nuclear medicine 48(4):320-323, 2023. e-Pub 2023. PMID: 36758558.
6. Kono, M, Shatila, M, Xu, G, Lu, Y, Mathew, A, Mohajir, W, Varatharajalu, K, Qiao, W, Thomas, AS, Wang, Y. Obesity Measured via Body Mass Index May Be Associated with Increased Incidence but Not Worse Outcomes of Immune-Mediated Diarrhea and Colitis. Cancers 15(8), 2023. e-Pub 2023. PMID: 37190257.
7. Awiwi, M, Abudayyeh, A, Hassan, NA, Diab, A, Gjoni, M, Xu, G, Vikram, R, Elsayes, KM. Imaging features of immune checkpoint inhibitor-related nephritis with clinical correlation. European Radiology 33(3):2227-2238, 2023. e-Pub 2023. PMID: 36255488.
8. Cherng HJ, Xu G, Feng L, Steiner R, Fayad L, Strati P, Nair R, Nastoupil LJ, Lee HJ, Neelapu SS, Flowers CR, Rodriguez M, Wang M, Hagemeister F, Pinnix CC, Ramdial J, Srour S, Nieto Y, Rezvani K, Champlin R, Kebriaei P, Westin J, Macapinlac HA, Shpall E, Ahmed S. Positron emission tomography derived metrics in relapsed or refractory large B-cell lymphoma with residual disease before autologous stem cell transplant. British Journal of Haematology 200(1):35-44, 2023. e-Pub 2022. PMID: 36068929.
9. Gu J, Lu Y, Xu G. Mismatched Lesions on 18F-FDG PET and 18F-Fluciclovine PET Images in a Patient With Metastatic Prostate Small Cell Carcinoma. Clin Nucl Med 47(3):255-257, 2022. e-Pub 2022. PMID: 34392287.
10. Wang ML, Jain P, Zhao S, Lee HJ, Nastoupil L, Fayad L, Ok CY, Kanagal-Shamanna R, Hill HA, Yao Y, Hagemeister FB, Westin JR, Fowler N, Samaniego F, Steiner R, Nair R, Iyer SP, Navsaria L, Badillo M, Research Group MC, Feng L, Xuelin H, Nogueras Gonzalez GM, Xu G, Wagner-Bartak N, Thirumurthi S, Santos D, Tang G, Lin P, Wang SA, Jorgensen J, Yin CC, Li S, Patel KP, Vega F, Medeiros LJ, Flowers CR, Wang L. Ibrutinib-rituximab followed by R-HCVAD as frontline treatment for young patients (=65 years) with mantle cell lymphoma (WINDOW-1): a single-arm, phase 2 trial. Lancet Oncol 23(3):406-415, 2022. e-Pub 2022. PMID: 35074072.
11. Jimenez JE, Dai D, Xu G, Zhao R, Li T, Pan T, Wang L, Lin Y, Wang Z, Jaffray D, Hazle JD, Macapinlac HA, Wu J, Lu Y. Lesion-Based Radiomics Signature in Pretherapy 18F-FDG PET Predicts Treatment Response to Ibrutinib in Lymphoma. Clin Nucl Med 47(3):209-218, 2022. e-Pub 2022. PMID: 35020640.
12. Jain P, Zhao S, Lee HJ, Hill HA, Ok CY, Kanagal-Shamanna R, Hagemeister FB, Fowler N, Fayad L, Yao Y, Liu Y, Moghrabi OB, Navsaria L, Feng L, Nogueras Gonzalez GM, Xu G, Thirumurthi S, Santos D, Iliescu C, Tang G, Medeiros LJ, Vega F, Avellaneda M, Badillo M, Flowers CR, Wang L, Wang ML. Ibrutinib With Rituximab in First-Line Treatment of Older Patients With Mantle Cell Lymphoma. J Clin Oncol 40(2):202-212, 2022. e-Pub 2022. PMID: 34797699.
13. Nguyen TT, Bhosale PR, Xu G, Pan T, Wei P, Lu Y. Comparison of PSMA-based 18F-DCFPyL PET/CT and pelvic multiparametric MRI for lesion detection in the pelvis in patients with prostate cancer. Am J Nucl Med Mol Imaging 12(6):166-179, 2022. e-Pub 2022. PMID: 36636233.
14. Xu G, Lu Y. Optimal Time Point for 68Ga-PSMA-11 PET/CT Imaging in the Assessment of Suspected Metastatic Prostate Cancer in the Bladder of Postprostatectomy Patient. Clin Nucl Med 46(8):675-676, 2021. e-Pub 2021. PMID: 33577202.
15. Xu G, Lu Y. Progression of Cabozantinib-Related Osteonecrosis Mimicking Metastases on Bone Scan. Clin Nucl Med 46(7):592-594, 2021. e-Pub 2021. PMID: 33577198.
16. Xu G, Lu Y. COVID-19 mRNA Vaccination-Induced Lymphadenopathy Mimics Lymphoma Progression on FDG PET/CT. Clin Nucl Med 46(4):353-354, 2021. e-Pub 2021. PMID: 33591026.
17. Liheng M, Xu, G, Balzano RF, Yuying L, Weifeng H, Ning Y, Yayun J, Mouyuan L, Guglielmi G. The value of DTI: achieving high diagnostic performance for brain metastasis. Radiol Med 126(2):291-298, 2021. e-Pub 2021. PMID: 32564269.
18. Teyateeti A, Teyateeti A, Ravizzini GC, Xu G, Tang C, Tu SM, Macapinlac HA, Lu Y. Diagnostic performance of 18F-fluciclovine PET/CT in prostate cancer patients with rising PSA level = 0.5 ng/ml after multiple treatment failures. Am J Nucl Med Mol Imaging 11(2):87-98, 2021. e-Pub 2021. PMID: 34079638.
19. Zhao S, Kanagal-Shamanna R, Navsaria L, Ok CY, Zhang S, Nomie K, Han G, Hao D, Hill HA, Jiang C, Yao Y, Nastoupil L, Westin J, Fayad L, Nair R, Steiner R, Ahmed S, Samaniego F, Iyer SP, Oriabure O, Chen W, Song X, Zhang J, Badillo M, Moghrabi O, Aranda J, Tang G, Yin CC, Patel K, Medeiros LJ, Li S, Vega F, Thirumurthi S, Xu G, Neelapu S, Flowers CR, Romaguera J, Fowler N, Wang L, Wang ML, Jain P. Efficacy of venetoclax in high risk relapsed mantle cell lymphoma (MCL) - outcomes and mutation profile from venetoclax resistant MCL patients. Am J Hematol 95(6):623-629, 2020. e-Pub 2020. PMID: 32239765.
20. Zhou Z, Xu G, Son JB, Ma J. Computer-aided detection of mantle cell lymphoma on 18F-FDG PET/CT using a deep learning convolutional neural network. THe Journal of Nuclear Medicine 61(supplement 1), 2020. e-Pub 2020.
21. Jain P, Zhang S, Kanagal-Shamanna R, Ok CY, Nomie K, Gonzalez GN, Gonzalez-Pagan O, Hill HA, Lee HJ, Fayad L, Westin J, Nastoupil L, Hagemeister F, Chen W, Oriabure O, Badillo M, Jiang C, Yixin Y, Li S, Tang G, Yin CC, Patel KP, Medeiros LJ, Nair R, Ahmed S, Iyer SP, Thirumurthi S, Champlin R, Xu G, Tinsu P, Santos D, Wang R, Han G, Zhang J, Song X, Neelapu S, Romaguera J, Futreal A, Flowers C, Fowler N, Wang L, Wang ML. Genomic profiles and clinical outcomes of de novo blastoid/pleomorphic MCL are distinct from those of transformed MCL. Blood Adv 4(6):1038-1050, 2020. e-Pub 2020. PMID: 32191807.
22. Minamimoto R, Xu G, Jamali M, Holley D, Barkhodari A, Zaharchuk G, Iagaru A. Semiquantitative Assessment of 18F-FDG Uptake in the Normal Skeleton: Comparison Between PET/CT and Time-of-Flight Simultaneous PET/MRI. AJR Am J Roentgenol 209(5):1136-1142, 2017. e-Pub 2017. PMID: 28777652.
23. Douglas D, Goubran M, Wilson E, Xu G, Tripathi P, Holley D, Chao S, Wintermark M, Quon A, Zeineh M, Vasanawala M, Zaharchuk G. Correlation between arterial spin labeling MRI and dynamic FDG on PET-MR in Alzheimer's disease and non-Alzhiemer's disease patients. EJNMMI Phys 2(Suppl 1):A83, 2015. e-Pub 2015. PMID: 26956345.
24. Hiniker SM, Pollom EL, Khodadoust MS, Kozak MM, Xu G, Quon A, Advani RH, Hoppe RT. Value of surveillance studies for patients with stage I to II diffuse large B-cell lymphoma in the rituximab era. Int J Radiat Oncol Biol Phys 92(1):99-106, 2015. e-Pub 2015. PMID: 25863757.
25. Ly M, Canu E, Xu G, Oh J, McLaren DG, Dowling NM, Alexander AL, Sager MA, Johnson SC, Bendlin BB. Midlife measurements of white matter microstructure predict subsequent regional white matter atrophy in healthy adults. Hum Brain Mapp 35(5):2044-54, 2014. e-Pub 2014. PMID: 23861348.
26. Okonkwo OC, Xu G, Oh JM, Dowling NM, Carlsson CM, Gallagher CL, Birdsill AC, Palotti M, Wharton W, Hermann BP, LaRue A, Bendlin BB, Rowley HA, Asthana S, Sager MA, Johnson SC. Cerebral blood flow is diminished in asymptomatic middle-aged adults with maternal history of Alzheimer's disease. Cereb Cortex 24(4):978-88, 2014. e-Pub 2014. PMID: 23236200.
27. Johnson SC, Christian BT, Okonkwo OC, Oh JM, Harding S, Xu G, Hillmer AT, Wooten DW, Murali D, Barnhart TE, Hall LT, Racine AM, Klunk WE, Mathis CA, Bendlin BB, Gallagher CL, Carlsson CM, Rowley HA, Hermann BP, Dowling NM, Asthana S, Sager MA. Amyloid burden and neural function in people at risk for Alzheimer's Disease. Neurobiol Aging 35(3):576-84, 2014. e-Pub 2014. PMID: 24269021.
28. Birdsill AC, Carlsson CM, Willette AA, Okonkwo OC, Johnson SC, Xu G, Oh JM, Gallagher CL, Koscik RL, Jonaitis EM, Hermann BP, LaRue A, Rowley HA, Asthana S, Sager MA, Bendlin BB. Low cerebral blood flow is associated with lower memory function in metabolic syndrome. Obesity (Silver Spring) 21(7):1313-20, 2013. e-Pub 2013. PMID: 23687103.
29. Willette AA, Xu G, Johnson SC, Birdsill AC, Jonaitis EM, Sager MA, Hermann BP, La Rue A, Asthana S, Bendlin BB. Insulin resistance, brain atrophy, and cognitive performance in late middle-aged adults. Diabetes Care 36(2):443-9, 2013. e-Pub 2013. PMID: 23069842.
30. Farbota KD, Sodhi A, Bendlin BB, McLaren DG, Xu G, Rowley HA, Johnson SC. Longitudinal volumetric changes following traumatic brain injury: a tensor-based morphometry study. J Int Neuropsychol Soc 18(6):1006-18, 2012. e-Pub 2012. PMID: 22883443.
31. Carlsson CM, Xu G, Wen Z, Barnet JH, Blazel HM, Chappell RJ, Stein JH, Asthana S, Sager MA, Alsop DC, Rowley HA, Fain SB, Johnson SC. Effects of atorvastatin on cerebral blood flow in middle-aged adults at risk for Alzheimer's disease: a pilot study. Curr Alzheimer Res 9(8):990-7, 2012. e-Pub 2012. PMID: 22175654.
32. Kastman EK, Willette AA, Coe CL, Bendlin BB, Kosmatka KJ, McLaren DG, Xu G, Canu E, Field AS, Alexander AL, Voytko ML, Beasley TM, Colman RJ, Weindruch RH, Johnson SC. A calorie-restricted diet decreases brain iron accumulation and preserves motor performance in old rhesus monkeys. J Neurosci 32(34):11897-904, 2012. e-Pub 2012. PMID: 23082321.
33. McLaren DG, Ries ML, Xu G, Johnson SC. A generalized form of context-dependent psychophysiological interactions (gPPI): a comparison to standard approaches. Neuroimage 61(4):1277-86, 2012. e-Pub 2012. PMID: 22484411.
34. Gallagher CL, Johnson SC, Bendlin BB, Chung MK, Holden JE, Oakes TR, Brooks BR, Konopacki RA, Dogan S, Abbs JH, Xu G, Nickles RJ, Pyzalski RW, Dejesus OT, Brown WD. A longitudinal study of motor performance and striatal [18F]fluorodopa uptake in Parkinson's disease. Brain Imaging Behav 5(3):203-11, 2011. e-Pub 2011. PMID: 21556744.
35. Johnson SC, La Rue A, Hermann BP, Xu G, Koscik RL, Jonaitis EM, Bendlin BB, Hogan KJ, Roses AD, Saunders AM, Lutz MW, Asthana S, Green RC, Sager MA. The effect of TOMM40 poly-T length on gray matter volume and cognition in middle-aged persons with APOE ε3/ε3 genotype. Alzheimers Dement 7(4):456-65, 2011. e-Pub 2011. PMID: 21784354.
36. Hinrichs C, Singh V, Xu G, Johnson SC, Neuroimaging Initiative AD. Predictive markers for AD in a multi-modality framework: an analysis of MCI progression in the ADNI population. Neuroimage 55(2):574-89, 2011. e-Pub 2011. PMID: 21146621.
37. Gallagher CL, Oakes TR, Johnson SC, Chung MK, Holden JE, Bendlin BB, McLaren DG, Xu G, Nickles RJ, Pyzalski R, DeJesus O, Brown WD. Rate of 6-[18F]fluorodopa uptake decline in striatal subregions in Parkinson's disease. Mov Disord 26(4):614-20, 2011. e-Pub 2011. PMID: 21449008.
38. Kastman EK, Willette AA, Coe CL, Bendlin BB, Kosmatka KJ, McLaren DG, Xu G, Canu E, Field AS, Alexander AL, Voytko ML, Beasley TM, Colman RJ, Weindruch RH, Johnson SC. A calorie-restricted diet decreases brain iron accumulation and preserves motor performance in old rhesus monkeys. J Neurosci 30(23):7940-7, 2010. e-Pub 2010. PMID: 20534842.
39. Xu G, Rowley HA, Wu G, Alsop DC, Shankaranarayanan A, Dowling M, Christian BT, Oakes TR, Johnson SC. Reliability and precision of pseudo-continuous arterial spin labeling perfusion MRI on 3.0 T and comparison with 15O-water PET in elderly subjects at risk for Alzheimer's disease. NMR Biomed 23(3):286-93, 2010. e-Pub 2010. PMID: 19953503.
40. Bendlin BB, Fitzgerald ME, Ries ML, Xu G, Kastman EK, Thiel BW, Rowley HA, Lazar M, Alexander AL, Johnson SC. White matter in aging and cognition: a cross-sectional study of microstructure in adults aged eighteen to eighty-three. Dev Neuropsychol 35(3):257-77, 2010. e-Pub 2010. PMID: 20446132.
41. Hinrichs C, Singh V, Mukherjee L, Xu G, Chung MK, Johnson SC, Neuroimaging Initiative AD. Spatially augmented LPboosting for AD classification with evaluations on the ADNI dataset. Neuroimage 48(1):138-49, 2009. e-Pub 2009. PMID: 19481161.
42. Xu G, McLaren DG, Ries ML, Fitzgerald ME, Bendlin BB, Rowley HA, Sager MA, Atwood C, Asthana S, Johnson SC. The influence of parental history of Alzheimer's disease and apolipoprotein E epsilon4 on the BOLD signal during recognition memory. Brain 132(Pt 2):383-91, 2009. e-Pub 2009. PMID: 18829694.
43. Hinrichs C, Singh V, Xu G, Johnson S. MKL for robust multi-modality AD classification. Med Image Comput Comput Assist Interv 12(Pt 2):786-94, 2009. e-Pub 2009. PMID: 20426183.
44. Xu G, Fitzgerald ME, Wen Z, Fain SB, Alsop DC, Carroll T, Ries ML, Rowley HA, Sager MA, Asthana S, Johnson SC, Carlsson CM. Atorvastatin therapy is associated with greater and faster cerebral hemodynamic response. Brain Imaging Behav 2(2):94, 2008. e-Pub 2008. PMID: 20157644.
45. Xu Y, Xu G, Wu G, Antuono P, Rowe DB, Li SJ. The phase shift index for marking functional asynchrony in Alzheimer's disease patients using fMRI. Magn Reson Imaging 26(3):379-92, 2008. e-Pub 2008. PMID: 18164158.
46. Xu Y, Wu G, Rowe DB, Ma Y, Zhang R, Xu G, Li SJ. COmplex-Model-Based Estimation of thermal noise for fMRI data in the presence of artifacts. Magn Reson Imaging 25(7):1079-88, 2007. e-Pub 2007. PMID: 17707170.
47. Xu G, Xu Y, Wu G, Antuono PG, Hammeke TA, Li SJ. Task-modulation of functional synchrony between spontaneous low-frequency oscillations in the human brain detected by fMRI. Magn Reson Med 56(1):41-50, 2006. e-Pub 2006. PMID: 16767759.
48. Yang Z, Xu G. Craniopagus twins. Chin Med J (Engl) 115(8):1262-3, 2002. e-Pub 2002. PMID: 12515280.

Review Articles

1. Xu G, Lu Y. 68Ga-PSMA-11 PET Identified Tumor Recurrence in Prostatectomy Bed With Rising PSA of 0.9 ng/mL but Negative on MRI and 18F-Fluciclovine PET Scan. Clin Nucl Med 47(4):378-379, 2022. e-Pub 2022. PMID: 35020642.
2. Jimenez C, Xu G, Varghese J, Graham PH, Campbell MT, Lu Y. New Directions in Treatment of Metastatic or Advanced Pheochromocytomas and Sympathetic Paragangliomas: an American, Contemporary, Pragmatic Approach. Curr Oncol Rep 24(1):89-98, 2022. e-Pub 2022. PMID: 35061191.
3. Lane DL, Neelapu SS, Xu G, Weaver O. COVID-19 Vaccine-Related Axillary and Cervical Lymphadenopathy in Patients with Current or Prior Breast Cancer and Other Malignancies: Cross-Sectional Imaging Findings on MRI, CT, and PET-CT. Korean J Radiol 22(12):1938-1945, 2021. e-Pub 2021. PMID: 34719892.
4. Varghese J, Rohren E, Guofan X. Radioiodine Imaging and Treatment in Thyroid Disorders. Neuroimaging Clin N Am 31(3):337-344, 2021. e-Pub 2021. PMID: 34243868.
5. Li D, Patel CB, Xu G, Iagaru A, Zhu Z, Zhang L, Cheng Z. Visualization of Diagnostic and Therapeutic Targets in Glioma With Molecular Imaging. Front Immunol 11:592389, 2020. e-Pub 2020. PMID: 33193439.
6. Prabhakaran V, Nair VA, Austin BP, La C, Gallagher TA, Wu Y, McLaren DG, Xu G, Turski P, Rowley H. Current status and future perspectives of magnetic resonance high-field imaging: a summary. Neuroimaging Clin N Am 22(2):373-97, xii, 2012. e-Pub 2012. PMID: 22548938.
7. Austin BP, Nair VA, Meier TB, Xu G, Rowley HA, Carlsson CM, Johnson SC, Prabhakaran V. Effects of hypoperfusion in Alzheimer's disease. J Alzheimers Dis 26 Suppl 3:123-33, 2011. e-Pub 2011. PMID: 21971457.

Book Chapters

1. Varghese J, Xu, G. Radioiodine Imaging and Treatment in Thyroid Disorders. In: Imaging of the Thyroid and Parathyroid. Neuroimaging Clinics by Elsevier, 337 - 344, 2021.
2. Xu G. In: 18F-Fluoride Imaging: Atlas of Interesting images. Research Gate, 61-68, 2020.
3. Xu G. 18F-Fluoride Imaging: Normal Variants and Artifacts. In: Clinicians’ Guides to Radionuclide Hybrid Imaging book series. Springer, 9-17, 2019.

Patents

1. Shi-Jiang, LiYin, Xu, Guofan, XuGaohong, Wu. MRI Methods for producing an index indicative of brain disorders. Patent Number: US20060241382A1.