Huili Zhu, MD
Department of Gastrointestinal Medical Oncology, Division of Cancer Medicine
Present Title & Affiliation
Primary Appointment
Assistant Professor, Clinical Faculty Appointment, Department of GI Medical Oncology, Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas
Education & Training
Degree-Granting Education
2018 | Geisel School of Medicine at Dartmouth, Hanover, NH, US, MD |
2012 | Columbia University, New York, NY, US, Chemical Engineering, BS |
Postgraduate Training
2021-2024 | Fellow, Hematology and Oncology, Baylor College of Medicine, Houston, TX |
2018-2021 | Resident, Internal Medicine, Icahn School of Medicine at Mount Sinai, New York, NY |
Honors & Awards
2024 | Conquer Cancer-Zentalis Women Who Conquer Cancer Young Investigator Award |
2024 | Excellence in Patient Care for GI Oncology – Fellow of the Year, Baylor College of Medicine |
2024 | Distinguished Fellow Educator Award, Baylor College of Medicine |
2023 | CPRIT Scholar, Cancer Prevention & Research Institute of Texas |
2023 | Chief Fellow, Department of Hematology and Oncology, Baylor College of Medicine |
2022 | TxSCO Fellows Abstract Competition winner |
2022 | Fellow of the Year, Center for Cell and Gene Therapy, Baylor College of Medicine |
2022 | ASCO Conquer Cancer Merit Award |
2021 | Research Day Poster of Distinction Award, Icahn School of Medicine at Mount Sinai |
2019 | Research Day Poster of Distinction Award, Icahn School of Medicine at Mount Sinai |
2015 | Chinese American Medical Society (CAMS) Summer Research Fellowship |
2015 | Science Scholar, Geisel School of Medicine at Dartmouth |
2014 | William H. Morton Memorial Scholar, Geisel School of Medicine at Dartmouth |
2014 | The Merck Company Foundation Scholar, Geisel School of Medicine at Dartmouth |
2012 | United States President’s Volunteer Service Award |
2012 | Dean’s List (four years), Columbia University |
2010 | Robert C. Byrd Honors Scholar, Columbia University |
2008 | Jee Yin and C. Heung Au Named Scholar, Columbia University |
Professional Memberships
Selected Publications
Peer-Reviewed Articles
- Zhu H, Choi J, Kui N, Yang T, Wei P, Li D, Sun R. Identification of Pancreatic Cancer Germline Risk Variants With Effects That Are Modified by Smoking. JCO Precis Oncol 8:e2300355, 2024. PMID: 38564682.
- Kim Y, Zhu L, Zhu H, Li X, Huang Y, Gu C, Bush H, Chung C, Zhang GQ. Characterizing cancer and COVID-19 outcomes using electronic health records. PLoS One 17(5):e0267584, 2022. PMID: 35507598.
- Bhalla S, Zhu H, Lin JY, Ozbek U, Wilck EJ, Chang S, Chen X, Ward S, Harpaz N, Polydorides AD, Miller W, Fiel MI, Modica I, Fan W, Zeizafoun N, Ang C. Impact of pathological response after neoadjuvant chemotherapy on adjuvant therapy decisions and patient outcomes in gastrointestinal cancers. Cancer Rep (Hoboken) 4(6):e1412, 2021. PMID: 34032391.
- Grivas P, Khaki AR, Wise-Draper TM, French B, Hennessy C, Hsu CY, Shyr Y, Li X, Choueiri TK, Painter CA, Peters S, Rini BI, Thompson MA, Mishra S, Rivera DR, Acoba JD, Abidi MZ, Bakouny Z, Bashir B, Bekaii-Saab T, Berg S, Bernicker EH, Bilen MA, Bindal P, Bishnoi R, Bouganim N, Bowles DW, Cabal A, Caimi PF, Chism DD, Crowell J, Curran C, Desai A, Dixon B, Doroshow DB, Durbin EB, Elkrief A, Farmakiotis D, Fazio A, Fecher LA, Flora DB, Friese CR, Fu J, Gadgeel SM, Galsky MD, Gill DM, Glover MJ, Goyal S, Grover P, Gulati S, Gupta S, Halabi S, Halfdanarson TR, Halmos B, Hausrath DJ, Hawley JE, Hsu E, Huynh-Le M, Hwang C, Jani C, Jayaraj A, Johnson DB, Kasi A, Khan H, Koshkin VS, Kuderer NM, Kwon DH, Lammers PE, Li A, Loaiza-Bonilla A, Low CA, Lustberg MB, Lyman GH, McKay RR, McNair C, Menon H, Mesa RA, Mico V, Mundt D, Nagaraj G, Nakasone ES, Nakayama J, Nizam A, Nock NL, Park C, Patel JM, Patel KG, Peddi P, Pennell NA, Piper-Vallillo AJ, Puc M, Ravindranathan D, Reeves ME, Reuben DY, Rosenstein L, Rosovsky RP, Rubinstein SM, Salazar M, Schmidt AL, Schwartz GK, Shah MR, Shah SA, Shah C, Shaya JA, Singh SRK, Smits M, Stockerl-Goldstein KE, Stover DG, Streckfuss M, Subbiah S, Tachiki L, Tadesse E, Thakkar A, Tucker MD, Verma AK, Vinh DC, Weiss M, Wu JT, Wulff-Burchfield E, Xie Z, Yu PP, Zhang T, Zhou AY, Zhu H, Zubiri L, Shah DP, Warner JL, Lopes G. Association of clinical factors and recent anticancer therapy with COVID-19 severity among patients with cancer: a report from the COVID-19 and Cancer Consortium. Ann Oncol 32(6):787-800, 2021. PMID: 33746047.
- Zhu H, Welinsky S, Soper ER, Brown KL, Abul-Husn NS, Lucas AL. Genetic Variants in Patients With a Family History of Pancreatic Cancer: Impact of Multigene Panel Testing. Pancreas 50(4):602-606, 2021. PMID: 33939675.
- Jun T, Ozbek U, Dharmapuri S, Hardy-Abeloos C, Zhu H, Lin JY, Personeni N, Pressiani T, Nishida N, Lee PC, Lee CJ, Hildebrand H, Nimkar N, Paul S, Fessas P, Naeem M, Bettinger D, Khan U, Saeed A, Huang YH, Kudo M, Rimassa L, Marron TU, Pinato DJ, Ang C. Antacid exposure and immunotherapy outcomes among patients with advanced hepatocellular carcinoma. Ther Adv Med Oncol 13(None):17588359211010937, 2021. PMID: 33995594.
- Rivera DR, Peters S, Panagiotou OA, Shah DP, Kuderer NM, Hsu CY, Rubinstein SM, Lee BJ, Choueiri TK, de Lima Lopes G Jr, Grivas P, Painter CA, Rini BI, Thompson MA, Arcobello J, Bakouny Z, Doroshow DB, Egan PC, Farmakiotis D, Fecher LA, Friese CR, Galsky MD, Goel S, Gupta S, Halfdanarson TR, Halmos B, Hawley JE, Khaki AR, Lemmon CA, Mishra S, Olszewski AJ, Pennell NA, Puc MM, Revankar SG, Schapira L, Schmidt A, Schwartz GK, Shah SA, Wu JT, Xie Z, Yeh AC, Zhu H, Shyr Y, Lyman GH, Warner JL. Utilization of COVID-19 Treatments and Clinical Outcomes among Patients with Cancer: A COVID-19 and Cancer Consortium (CCC19) Cohort Study. Cancer Discov 10(10):1514-1527, 2020. PMID: 32699031.
- Franses JW, Philipp J, Missios P, Bhan I, Liu A, Yashaswini C, Tai E, Zhu H, Ligorio M, Nicholson B, Tassoni EM, Desai N, Kulkarni AS, Szabolcs A, Hong TS, Liss AS, Fernandez-Del Castillo C, Ryan DP, Maheswaran S, Haber DA, Daley GQ, Ting DT. Pancreatic circulating tumor cell profiling identifies LIN28B as a metastasis driver and drug target. Nat Commun 11(1):3303, 2020. PMID: 32620742.
- Sun R, Zhu H, Wei LJ. Assessing the Prognostic Value of the Automated Bone Scan Index for Prostate Cancer. JAMA Oncol 5(2):270, 2019. PMID: 30543368.
- Aceto N, Bardia A, Wittner BS, Donaldson MC, O'Keefe R, Engstrom A, Bersani F, Zheng Y, Comaills V, Niederhoffer K, Zhu H, Mackenzie O, Shioda T, Sgroi D, Kapur R, Ting DT, Moy B, Ramaswamy S, Toner M, Haber DA, Maheswaran S. AR Expression in Breast Cancer CTCs Associates with Bone Metastases. Mol Cancer Res 16(4):720-727, 2018. PMID: 29453314.
- Miyamoto DT, Zheng Y, Wittner BS, Lee RJ, Zhu H, Broderick KT, Desai R, Fox DB, Brannigan BW, Trautwein J, Arora KS, Desai N, Dahl DM, Sequist LV, Smith MR, Kapur R, Wu CL, Shioda T, Ramaswamy S, Ting DT, Toner M, Maheswaran S, Haber DA. RNA-Seq of single prostate CTCs implicates noncanonical Wnt signaling in antiandrogen resistance. Science 349(6254):1351-6, 2015. PMID: 26383955.
- Sarioglu AF, Aceto N, Kojic N, Donaldson MC, Zeinali M, Hamza B, Engstrom A, Zhu H, Sundaresan TK, Miyamoto DT, Luo X, Bardia A, Wittner BS, Ramaswamy S, Shioda T, Ting DT, Stott SL, Kapur R, Maheswaran S, Haber DA, Toner M. A microfluidic device for label-free, physical capture of circulating tumor cell clusters. Nat Methods 12(7):685-91, 2015. PMID: 25984697.
- Ting DT, Wittner BS, Ligorio M, Vincent Jordan N, Shah AM, Miyamoto DT, Aceto N, Bersani F, Brannigan BW, Xega K, Ciciliano JC, Zhu H, MacKenzie OC, Trautwein J, Arora KS, Shahid M, Ellis HL, Qu N, Bardeesy N, Rivera MN, Deshpande V, Ferrone CR, Kapur R, Ramaswamy S, Shioda T, Toner M, Maheswaran S, Haber DA. Single-cell RNA sequencing identifies extracellular matrix gene expression by pancreatic circulating tumor cells. Cell Rep 8(6):1905-1918, 2014. PMID: 25242334.
- Aceto N, Bardia A, Miyamoto DT, Donaldson MC, Wittner BS, Spencer JA, Yu M, Pely A, Engstrom A, Zhu H, Brannigan BW, Kapur R, Stott SL, Shioda T, Ramaswamy S, Ting DT, Lin CP, Toner M, Haber DA, Maheswaran S. Circulating tumor cell clusters are oligoclonal precursors of breast cancer metastasis. Cell 158(5):1110-1122, 2014. PMID: 25171411.
- Yu M, Bardia A, Aceto N, Bersani F, Madden MW, Donaldson MC, Desai R, Zhu H, Comaills V, Zheng Z, Wittner BS, Stojanov P, Brachtel E, Sgroi D, Kapur R, Shioda T, Ting DT, Ramaswamy S, Getz G, Iafrate AJ, Benes C, Toner M, Maheswaran S, Haber DA. Cancer therapy. Ex vivo culture of circulating breast tumor cells for individualized testing of drug susceptibility. Science 345(6193):216-20, 2014. PMID: 25013076.
Other Articles
- Zhu H, Jin RU The role of the fibroblast in Barrett's esophagus and esophageal adenocarcinoma. Curr Opin Gastroenterol 40(4):319-327, 2024. PMID: 38626060.
- Gao Z, Azar J, Zhu H, Williams-Perez S, Kang SW, Marginean C, Rubinstein MP, Makawita S, Lee HS, Camp ER Translational and oncologic significance of tertiary lymphoid structures in pancreatic adenocarcinoma. Front Immunol 15(None):1324093, 2024. PMID: 38361928.
- Abidi M, Aboulafia DM, Accordino MK, Zhu H A Systematic Framework to Rapidly Obtain Data on Patients with Cancer and COVID-19: CCC19 Governance, Protocol, and Quality Assurance. Cancer Cell 38(6):761-6, 2020. PMID: 33176160.
- Maghsoudi A, Sada Y, Nowakowski S, Zhu H, Yarlagadda S, Li A, Razjoiyan A A Multi-institutional natural language processing pipeline to extract performance status from electronic health records. Cancer Control None(None):None. PMID: None.
Abstracts
- Zhu H, Keeling SS, Liu KS, Musher BL. Immune checkpoint inhibitors in minority patients with mismatch repair-deficient gastrointestinal cancers. IJCCD None(None):None, 2024. PMID: None.
- Zhu H, Lieber JJ. COVID-19 and spontaneous pneumopericardium: a case report. Journal of Scientific Innovation in Medicine 3(3):4, 2020. PMID: None.
Book Chapters
- Musher B, Zhu H. Chapter 4: Therapy for Metastatic Pancreatic Cancer. In: Pancreatic Cancer Current Therapeutics and Future Directions. None. Springer Publishing Company, None, 2023.
- Riggins K, Zhu H. Chapter 8: Gastric Cancer. In: Tumor Board Review: Evidence-Based Case Reviews and Questions. 3rd. Springer Publishing Company, None, 2022.
- Zhu H, Yeung Z, Musher B, Makawita S. Chapter 9: Pancreatic Cancer. In: Tumor Board Review: Evidence-Based Case Reviews and Questions. 3rd. Springer Publishing Company, None, 2022.
Grant & Contract Support
Title: | The role of human esophageal myofibroblasts in Barrett’s esophagus and esophageal adenocarcinoma |
Funding Source: | Cancer Prevention & Research Institute of Texas |
Role: | Fellow Investigator |