HyunSeon Christine Kang
Department of Abdominal Imaging, Division of Diagnostic Imaging
About Dr. Kang
Dr. H. Christine Kang is an Associate Professor of Diagnostic Radiology at the University of Texas MD Anderson Cancer Center. She obtained her medical degree from Seoul National University, Seoul, South Korea. Dr. Kang then moved to St. Louis, MO and received her PhD in Neurosciences from Washington University in St. Louis, studying functional MRI of cognitive task control. She completed her Diagnostic Radiology residency and Abdominal Imaging fellowship at the Hospital of the University of Pennsylvania. During this time, she became interested in imaging biomarkers of tumor response and conducted research on early MRI findings of renal cell carcinoma after targeted therapy. Her research and clinical interests focus on imaging biomarkers of various tumors, including cholangiocarcinoma and renal cell carcinoma.
Present Title & Affiliation
Primary Appointment
Associate Professor, Department of Abdominal Imaging, Division of Diagnostic Imaging, The University of Texas MD Anderson Cancer Center, Houston, TX
Dual/Joint/Adjunct Appointment
Associate Professor, McGovern Medical School at UTHealth, Houston, TX
Research Interests
Imaging biomarkers of tumor response
Imaging of liver tumors
MRI of prostate carcinoma
Clinical Interests
Tumor biomarkers
Liver tumors
Prostate carcinoma
Education & Training
Degree-Granting Education
| 2004 | Washington University School of Medicine, St. Louis, MO, USA, PHD, Neuroscience |
| 1998 | Seoul National University College of Medicine, Seoul, KOR, MD, Medicine |
| 1994 | Seoul National University College of Natural Sciences, Seoul, KOR, BS, Pre-med |
Postgraduate Training
| 2011-2012 | Clinical Fellowship, Abdominal Radiology, Hospital of the University of Pennsylvania, Philadelphia, PA |
| 2007-2011 | Clinical Residency, Diagnostic Radiology, Hospital of the University of Pennsylvania, Philadelphia, PA |
| 2006-2007 | Clinical Internship, Internal Medicine, Albert Einstein Medical Center, Philadelphia, PA |
| 1999-2000 | Clinical Internship, Medicine, Seoul National University Hospital, Seoul |
Board Certifications
| 2011 | American Board of Radiology |
Experience & Service
Academic Appointments
Associate Professor, Department of Diagnostic Radiology, Division of Diagnostic Imaging, The University of Texas MD Anderson Cancer Center, Houston, TX, 2018 - 2019
Assistant Professor, Department of Diagnostic & Interventional Imaging, The University of Texas Health Science Center at Houston, Houston, TX, 2013 - 2018
Assistant Professor, Department of Diagnostic Radiology, Division of Diagnostic Imaging, The University of Texas MD Anderson Cancer Center, Houston, TX, 2012 - 2018
Administrative Appointments/Responsibilities
Program Director, DI Research Residency Pathway, Department of Abdominal Imaging, The University of Texas MD Anderson Cancer Center, Houston, TX, 2017 - Present
Residency Site Director, Department of Abdominal Imaging, The University of Texas MD Anderson Cancer Center, Houston, TX, 2016 - Present
Other Appointments/Responsibilities
Lead, Liver Reporting, Tumor Measurement Initiative, The University of Texas MD Anderson Cancer Center, HOUSTON, TX, 2021 - Present
Lead, Prostate Reporting, Tumor Measurement Initiative, MD Anderson Cancer Center, Houston, TX, 2021 - Present
Member, Clinical Competency Committee, University of Texas Health Science Center, Houston Department of Diagnostic and Interventional Radiology, HOUSTON, TX, 2021 - Present
Member, Resident Selection Committee, University of Texas Health Science Center at Houston Radiology Residency Program, Houston, TX, 2016 - Present
Radiologist, Prostate Imaging and Focal Therapy Team, The University of Texas MD Anderson Cancer Center, Houston, 2016 - Present
Liaison, Hepatobiliary Radiologist, University of Texas MD Anderson Cancer Center, Houston, TX, 2015 - Present
Institutional Committee Activities
Member, Abdominal Imaging Prostate MR Quality Assurance Committee, 2021 - Present
Member, Clinical Radiology Education, 2020 - Present
Member, Abdominal Imaging Education Committee, 2018 - Present
Co-chair, Vice Chair for Education Selection Committee, 2017 - 2018
Co-Chair, Diagnostic Imaging Educational Functional Committee, 2017 - 2019
Member, Diagnostic Imaging Educational Functional Committee, 2016 - Present
Member, Faculty Senate, 2016 - 2019
Member, Diagnostic Imaging Clinical Functional Committee, 2015 - 2017
Member, Council on Gender Inclusiveness, 2013 - 2014
Honors & Awards
| 2022 | Certificate of Merit, European Society of Gastrointestinal Abdominal Radiology |
| 2019 | Diagnostic Radiology Outstanding Educator Award, The University of Texas MD Anderson Cancer Center |
| 2018 | Certificate of Merit, American Roentgen Ray Society |
| 2016 | Certificate of Merit, Radiological Society of North America |
| 2013 | Certificate of Merit, Radiological Society of North America |
| 2012 | Certificate of Merit, Radiological Society of North America |
| 2010 | David C. Leach, M.D. Award, American Council for Graduate Medical Education |
| 2009 | Scholarship, Society of Breast Imaging |
| 1992 | Full Tuition Scholarship, Seoul National University |
Professional Memberships
Selected Publications
Peer-Reviewed Articles
- Cox Veronica, Javle Milind, Sun Jia, Kang HC. Radiogenomics of intrahepatic cholangiocarcinoma: Correlation of imaging features with BAP1 and FGFR molecular subtypes. Comput Assist Tomogr 00(00), 2024. PMID: 38968316.
- Haddad A, Lendoire M, Paolucci I, Kang HC, Vauthey JN. Optimal imaging before local therapy of colorectal liver metastases. Lancet Oncol 25(3):e99, 2024. PMID: 38423067.
- Woodland McKell, Wood John, Anderson Brian, Kundu Suprateek, Lin Ethan, Koay Eugene, Odisio Bruno, Chung Caroline, Kang HC, Venkatesan Aradhana, Yedururi Sireesha, De Brian, Lin Yuan-Mao, Patel Ankit, Brock Kristy. Evaluating the performance of styleGAN2-ADA on medical images. Lecture Notes in Computer Science 13570, 2022.
- Anderson B, Rigaud B, Lin Y, Jones AK, Kang HC, Odisio B, Brock K. Automated segmentation of colorectal liver metastasis and liver ablation on contrast-enhanced CT images. Frontiers in Oncology, 2022. PMID: 36033508.
- Altok M, Demirel C, Kang HC, Choi H, John D, Inguillo IA, Davis JW, Ward JF. Impact of MRI/US fusion-guided prostate biopsy on biopsy-naïve patients: A single urologist's experience. BJUI Compass 3(1):19-25, 2022. e-Pub 2021. PMID: 35475153.
- Panettieri E, Maki H, Kim B, Kang HC, Cox V, Vega E, Mizuno T, Pant S, Javle M, Vauthey J, Kawaguchi Y. Arterial enhancement pattern predicts survival in patients with resectable and unresectable intrahepatic cholangiocarcinoma. Surgical Oncology, 2021. PMID: 34995974.
- Kang HC, Jo Nahyun, Bamashmos Anas Saeed, Ahmed Mona, Sun Jia, Ward John F, Choi Haesun. Accuracy of prostate magnetic resonance imaging: reader experience matters. EU Open Science 27:53-60, 2021. PMID: 33899028.
- Kaur H, Gabriel H, Taggart M, Kang HC, Konishi T, Rauch GM, Krishnan S, Chang G. MRI staging in an evolving management paradigm for rectal cancer, from the AJR special series on cancer staging. AJR Am J Roentgenol. e-Pub 2021. PMID: 33949877.
- Gupta S, Kang HC, Faria SC, Choyke PL, Kundra V. Tuberous sclerosis complex: renal and extrarenal imaging. Acad Radiol. e-Pub 2021. PMID: 33487538.
- Urkmez A, Ward J, Choi H, Troncoso P, Inguillo I, Gregg J, Altok M, Demire H, Qiao W, Kang HC. Temporal learning curve of a multidisciplinary team for magnetic resonance imaging/transrectal ultrasonography fusion prostate biopsy. BJUI, 2020. PMID: 33340435.
- Shapiro DD, Gregg JR, Lim AH, Nogueras-González GM, Choi H, Kang HC, Inguillo IA, Chapin BF, Davis JW, Ward JF. Comparing confirmatory biopsy outcomes between MRI-targeted biopsy and standard systematic biopsy among men being enrolled in prostate cancer active surveillance. BJU Int. e-Pub 2020. PMID: 32357283.
- Popnoe DO, Ng CS, Zhou S, Kaur H, Kang HC, Loyer EM, Kappadath SC, Jones AK. Comparison of virtual to true unenhanced abdominal computed tomography images acquired using rapid kV-switching dual energy imaging. PLoS One 15(9):e0238582, 2020. e-Pub 2020. PMID: 32966278.
- Gupta S, Kang HC, Sun J, Matrana MR, Tannir NM, Choi H. Tumor response criteria for assessing pazopanib first-line therapy in patients with metastatic renal cell carcinoma. Abdom Radiol. e-Pub 2019. PMID: 31822966.
- Yedururi S, Kang HC, Cox VL, Chawla S, Marcal L, Le O, Loyer EM. Tumor thrombus in venous drainage pathways of primary, recurrent and metastatic disease on routine oncologic imaging studies: Beyond hepatocellular carcinoma and renal cell carcinoma. BJR 92(1098), 2019. PMID: 30844299.
- Lee Andrew J, Loyer Evelyne M, Kang HC, Aloia Thomas A, Tzeng Ching-Wei, Vauthey Jean-Nicolas, Chun Yun Shin. Intrahepatic recurrence patterns predict survival after resection of colorectal liver metastases. Ann Surg Oncol 26(1):275-281. e-Pub 2018. PMID: 30362064.
- Haygood Tamara Miner, Mullins Barry, Sun Jia, Amini Behrang, Bhosale Priya R; Kang HC, Sagebiel Tara. Consultation and citation rates for prior imaging studies and documents in radiology. Journal of Medical Imaging 5(3), 2018. PMID: 29750178.
- Cox V, Bamashmos A, Foo W, Gupta S, Yedururi S, Garg N, Kang HC. Lynch Syndrome: genomics update and imaging review. Radiographics 38(2):483-499, 2018. PMID: 29528821.
- Kang HC, Gupta S, Wei W, Lu L, Matrana N, Tannier N, Choi H. Alternative response criteria and clinical risk factors in assessing tumor response in salvage therapy patients with metastatic renal cell carcinoma. Am J Roentgenol 209(6):1278-1284, 2017.
- Gupta S, Kang HC, Ganeshan D, Morani A, Gautam R, Choyke PL, Kundra V. The ABCs of BHD: An In-Depth Review of Birt-Hogg-Dubé Syndrome. AJR Am J Roentgenol 209(6):1291-1296, 2017. e-Pub 2017. PMID: 28981362.
- Thampy R, Elsayes K, Menias C, Pickhardt P, Kang HC, Deshmukh S, Ahmed K, Korivi B. Imaging features of rare mesenchymal liver tumors: beyond hemangiomas. Br J Radiol 90(1079), 2017. e-Pub 2017. PMID: 28766950.
- Allen BC, Florez E, Sirous R, Lirette ST, Griswold M, Remer EM, Wang ZJ, Bieszczad JE, Cox KL, Goenka AH, Howard-Claudio CM, Kang HC, Nandwana SB, Sanyal R, Shinagare AB, Henegan JC, Storrs J, Davenport MS, Ganeshan B, Vansanji A, Rini B, Smith AD. Comparative effectiveness of tumor response assessment methods: standard of care versus computer-assisted response evaluation. JCO Clin Cancer Inform 1:1-16, 2017. PMID: 30657391.
- Mizuno T, Sheth R, Yamamoto M, Kang HC, Yamashita S, Aloia TA, Chun YS, Lee JE, Vauthey JN, Conrad C. Laparoscopic glissonean pedicle transection - Takasaki- for negative fluorescent counterstaining of segment 6. Ann Surg Oncol 24(4):1046-1047, 2017. PMID: 27995453.
- Javle M, Bekaii-Saab T, Jain A, Wang Y, Kelley RK, Wang K, Kang HC, Catenacci D, Ali S, Krishnan S, Ahn D, Bocobo AG, Zuo M, Kaseb A, Miller V, Stephens PJ, Meric-Bernstam F, Shroff R, Ross J. Biliary cancer: utility of next-generation sequencing for clinical management. Cancer 122(24):3838-3847, 2016. PMID: 27622582.
- Yamashita S, Loyer E, Kang HC, Aloia TA, Chun YS, Mehran RJ, Eng C, Lee JE, Vauthey JN, Conrad C. Total transthoracic approach facilitates laparoscopic hepatic resection in patients with significant prior abdominal surgery. Ann Surg Oncol 24(5):1376-1377. e-Pub 2016. PMID: 27878479.
- Yedururi S, Kang HC, Wei W, Wagner-Bartak N, Marcal L, Stafford J, Willis B, Szklaruk J. Free-breathing radial volumetric interpolated breath-hold examination vs breath-hold cartesian volumetric interpolated breath-hold examination magnetic resonance imaging of the liver at 1.5T. WJR 8(7):707-715, 2016. e-Pub 2016.
- Javle M, Chaitanya C, Kang HC, Shroff R, Janku F, Surapaneni R, Zuo M, Barrera C, Alshamsi H, Krishnana S, Mishra L, Wolff R, Kaseb A, Thomas M, Siegel A. Her2/Neu directed therapy for biliary tract cancer. J Hematol Oncol 58(8), 2015.
- Gupta S, Kang HC, Ganeshan DM, Bathala T, Kundra V. Diagnostic approach to hereditary renal cell carcinoma. AJR Am J Roentgenol 204(5), 2015.
- Martin CA, Perini RF, Avadhani AN, Kang HC, Sun w, Redlinger M. Phase I and pharmacodynamic trial of everolimus in combination with cetuximab in patients with advanced cancer. Cancer 120(1):77-85, 2014. PMID: 24108668.
- Churi CR, Shroff R, Wang Y, Rashid A, Kang HC, Weatherly J, Zuo M, Zinner R, Hong D, Meric-Bernstam F, Janku F, Crane CH, Mishra L, Vauthey JN, Wolff RA, Mills G, Javle M. Mutation profiling in cholangiocarcinoma: prognostic and therapeutic implications. PLoS One 9(12):e115383, 2014. e-Pub 2014. PMID: 25536104.
- Kang HC, Menias CO, Gaballah AH, Shroff S, Taggart MW, Garg N, Elsayes KM. Beyond the gist: Mesenchymal tumors of the stomach. Radiographics 33(6):1673-1690, 2013. PMID: 24108557.
- Kang HC, Tan KS, Keefe SM, Heitjan DF, Siegelman ES, Flaherty KT, O'Dwyer PJ, Rosen MA. Magnetic resonance imaging assessment of early tumor response in metastatic renal cell carcinoma patients treated with sorafenib. AJR Am J Roentgenol 200(1):120-6, 2013. PMID: 23255750.
- Xue Y, Yu J, Kang HC, D, Englander S, Rosen MA, Song HK. Automatic coil selection for streak artifact reduction in radial magnetic resonance imaging. Magn Reson Med 67(2):470-6, 2012. e-Pub 2011. PMID: 21656562.
- Itri JN, Kang HC, Krishnan S, Nathan D, Scanlon MH. Using focused missed-case conferences to reduce discrepancies in musculoskeletal studies interpreted by residents on call. AJR Am J Roentgenol 197(4):W696-705, 2011. PMID: 21940542.
- Dosenbach NU, Visscher KM, Palmer ED, Miezin FM, Wenger KK, Kang HC, Burgund ED, Grimes AL, Schlaggar BL, Petersen SE. A core system for the implementation of task sets. Neuron 50(5):799-812, 2006. PMID: 16731517.
- Mukherjee P, Kang HC, Videen TO, McKinstry RC, Powers WJ, Derdeyn CP. Measurement of cerebral blood flow in chronic carotid occlusive disease: comparison of dynamic susceptibility contrast perfusion magnetic resonance imaging with positron emission tomography. AJNR Am J Neuroradiol 24(5):862-71, 2003. PMID: 12748086.
- Kang HC, Burgund ED, Lugar HM, Petersen SE, Schlaggar BL. Comparison of functional activation foci in children and adults using a common stereotactic space. Neuroimage 19(1):16-28, 2003. PMID: 12781724.
- Burgund ED, Kang HC, Kelly JE, Buckner RL, Snyder AZ, Petersen SE, Schlaggar BL. The feasibility of a common stereotactic space for children and adults in fMRI studies of development. Neuroimage 17(1):184-200, 2002. PMID: 12482076.
Invited Articles
- Ganeshan DM, Morani A, Ladha H, Bathala TK, Kang HC, Gupta S, Lalwani N, Kundra V.. Staging, surveillance and evaluation of response to therapy in renal cell carcinoma abdominal imaging. Abdominal Imaging 39(1), 2013. PMID: 24077815.
Abstracts
- Yedururi S, Kang HC, Loyer Evelyne M. Tumor thrombus in vascular drainage pathways: beyond hepatocellular and renal cell carcinoma. Society of Abdominal Imaging Annual Scientific Meeting Proceedings, 2017. e-Pub 2017.
- Allen B, Florez E, Sirous R, Lirette S, Griswold M, Remer E, Wang Z, Bieszczad J, Cox K, Goenka A, Howard-Claudio C, Kang HC, Nandwana S, Rupan S, Shinagare A, Henegan C, Storrs J, Davenport M, Rini B, Smith AD. Comparative effectiveness of tumor response assessment methods: standard-of-care versus computer-assisted response evaluation. JCO CCI 35(6 Supplement):432, 2017.
- Yedururi S, Chawla S, Kang HC, Cox VL, Lee, JE, Waguespack S. Multi-modality imaging of multiple endocrine neoplasia syndromes: emerging concepts in the diagnosis and treatment. What radiologists need to know. Radiological Society of North America Proceedings, 2016. e-Pub 2016.
- Bamashmos A, Muthalgiri CM, Cox VL, Gupta S, Yedururi S, Garg N, Kang HC. Beyond colorectal carcinoma: imaging spectrum of Lynch syndrome. Radiological Society of North America Proceedings, 2016. e-Pub 2016.
- Phuoc V, Chun Y, Vauthey J, Newhook T, Conrad C., Aloia T, Kang HC, Yedururi S, Loyer E. Radiographic predictors of intrahepatic recurrence after resection of colorectal liver metastases. Ann of Surg Oncol 20(Supplement 1):S116, 2016.
- Ahmed K, Menias CO, Deshmukh SP, Kang HC, Elsayes KM. Beyond hemangioma; rare mesenchymal tumors of the liver. Radiological Society of North America Proceedings, 2015.
- Yedururi S, Kang HC, Chawla S, Mclean VA, Shah KB, Loyer EM. Tumor thrombus in vascular drainage pathways: beyond hepatocellular and renal cell carcinomas. Radiological Society of North America Proceedings, 2015.
- Gupta S, Kang HC, Ganeshan DM, Morani A, Kundra V. The ABCs of BHD: an in-depth review of Birt-Hogg-Dubé syndrome. Radiological Society of North America Proceedings, 2015.
- Kang HC, Gupta S, Wei W, Lu L, Matrana M, Tannier N. Prognostic value of newly proposed response criteria in assessing tumor response in advanced renal cell carcinoma. Radiological Society of North America Proceedings, 2015.
- Gupta S, Kang HC, Ganeshan DM, Bathala TK, Kundra V. Diagnostic approach to hereditary renal cell carcinoma. Radiological Society of North America Proceedings, 2013.
- Bathala TK, Morani AC, Kang HC, Gupta S, Ganeshan DM, Kundra V. Oncogenics of clear cell renal cell carcinoma in the era of personalized medicine: what every radiologist needs to know. Radiological Society of North America Proceedings, 2013.
- Kang HC, Menias CO, Matta EJ, Galballah AH, Lubner MG, Elsayes KM. Beyond the gastrointestinal stromal tumors: mesenchymal tumors of the stomach. Radiological Society of North America Proceedings, 2012.
- Song HK, Yue Y, Englander S, Kang HC, Rosen MA. Comparison of the standard gadolinium concentration and signal difference methodologies for computation of perfusion parameters in dynamic contrast enhanced magnetic resonance imaging at various stereostatic radiosurgery. Proc Intl Soc Mag Reson Med 19:1072, 2011.
- Kang HC, Tan KS, Keefe SM, Heitjan DF, Flaherty KT, Siegelman ES, O'Dwyer PJ, Rosen MA. Magnetic resonance biomarkers of tumor response to multikinase inhibitor therapy. National Institute of Biomedical Imaging and Bioengineering Proceedings, 2010.
- Dosenbach H, Miezin FM, Palmer ED, Visscher KM, Wenger KK, Kang HC, Grimes AL, Burgund ED, Schlaggar BL, Petersen SE. Mixed blocked/event-related flow measured magnetic resonance imaging suggests that anterior cingulate/medial superior frontal cortex and anterior insula form a core network for the instantiation and maintenance of task set. Society of Neuroscience, 2005.
- Visscher KM, Palmer ED, Kang HC, Dosenbach NUF, Petersen SE. Potential control processes common to a range of tasks: sustained, task-related flow measured magnetic resonance imaging signals examined across 10 tasks. Society for Neuroscience, 2004.
- Kang HC, Miezin FM, Petersen SE. Different types of sustained and transient activity dissociated by practice. Society for Neuroscience Annual Meeting Proceedings, 2003.
- Kang HC, Miezin FM, Petersen SE. Sustained, block-related activity in more controlled and more automatic tasks: a mixed block/event-related flow measured magnetic resonance imaging study. Cognitive Neuroscience Society, 2003.
- Visscher KM, Palmer ED, Burgund ED, Kang HC, Miezin FM, Lyon JK, Buckner RL, Petersen SE. Sustained, block-related activity compared across four tasks shows both common and task-modulated responses. Cognitive Neuroscience Society, 2003.
- Mukherjee P, Kang HC, Videen TO, McKinstry RC, Powers WJ, Derdeyn C. Is time-to-peak a reliable surrogate measure of mean transit time in cerebrovascular occlusive disease?. International Computed Tomography/Magnetic Resonance Imaging Perfusion Symposium Proceedings, 2002.
- Mukherjee P, Kang HC, Videen TO, McKinstry RC, Powers WJ, Derdeyn C. Cerebral blood flow in carotid occlusive disease: comparison of dynamic susceptibility contrast perfusion magnetic resonance imaging with positron emission tomography. International Computed Tomography/Magnetic Resonance Imaging Perfusion Symposium Proceedings 24(5):862-71, 2002. PMID: 12748086.
- Kang HC, Burgund ED, Lugar HM, Petersen SE, Schlaggar BL. Comparison of functional activation foci in children and adults using a common stereotactic space. Cognitive Neuroscience Society 19(1):16-28, 2002. PMID: 12781724.
- Kang HC, Burgund ED, Lugar HM, Petersen SE, Schlaggar BL. Transforming brains into talairach space: a comparison of functional activation foci in 7 and 8 year old children and adults. Society for Neuroscience, 2001.
- Derdeyn CP, Kang HC, Mukherjee P, Videen TO, Lin W, McKinstry RC, Powers WJ. Absolute cerebral blood flow measured by magnetic resonance imaging: comparison with positron emission tomography. American Society of Neuroradiology Annual Meeting Proceedings:165-166, 2001.
- Burgund ED, Kang HC, Snyder AZ, Petersen SE, Schlaggar BL. Transforming children's brains into talairach space: a comparison of sulci in 7 and 8 year old children and adults. Cognitive Neuroscience Society, 2001.
Grant & Contract Support
| Title: | Development and Validation of Prognostic Radiomic Markers of Response and Recurrence for Patients with Colorectal Liver Metastases |
| Funding Source: | NIH/NCI |
| Role: | Co-Investigator |
| Title: | Anatomical Modeling to Improve the Precision of Image Guided Liver Ablation |
| Funding Source: | NIH/NIBIB |
| Role: | Co-Principal Investigator |
| Title: | Tumor Measurement Initiative |
| Funding Source: | The University of Texas MD Anderson Cancer Center |
| Role: | Co-Investigator |
Patient Reviews
CV information above last modified August 05, 2024