Isabella C. Glitza Oliva, M.D., Ph.D., M.S.

Peer-Reviewed Articles

1. Holbrook K, Lutzky J, Davies MA, Davis JM, Glitza IC, Amaria RN, Diab A, Patel SP, Amin A, Tawbi H. Intracranial antitumor activity with encorafenib plus binimetinib in patients with melanoma brain metastases: A case series. Cancer 126(3):523-530, 2020. e-Pub 2019. PMID: 31658370.
2. Menon H, Chen D, Ramapriyan R, Verma V, Barsoumian HB, Cushman TR, Younes AI, Cortez MA, Erasmus JJ, de Groot P, Carter BW, Hong DS, Glitza IC, Ferrarotto R, Altan M, Diab A, Chun SG, Heymach JV, Tang C, Nguyen QN, Welsh JW. Influence of low-dose radiation on abscopal responses in patients receiving high-dose radiation and immunotherapy. J Immunother Cancer 7(1):237, 2019. e-Pub 2019. PMID: 31484556.
3. Sprouse ML, Welte T, Boral D, Liu HN, Yin W, Vishnoi M, Goswami-Sewell D, Li L, Pei G, Jia P, Glitza-Oliva IC, Marchetti D. PMN-MDSCs Enhance CTC Metastatic Properties through Reciprocal Interactions via ROS/Notch/Nodal Signaling. Int J Mol Sci 20(8), 2019. e-Pub 2019. PMID: 31003475.
4. Johnson DH, Zobniw CM, Trinh VA, Ma J, Bassett RL, Abdel-Wahab N, Anderson J, Davis JE, Joseph J, Uemura M, Noman A, Abu-Sbeih H, Yee C, Amaria R, Patel S, Tawbi H, Glitza IC, Davies MA, Wong MK, Woodman S, Hwu WJ, Hwu P, Wang Y, Diab A. Correction to: Infliximab associated with faster symptom resolution compared with corticosteroids alone for the management of immune-related enterocolitis. J Immunother Cancer 7(1):107, 2019. e-Pub 2019. PMID: 30995944.
5. Safa H, Glitza Oliva IC. Cardiac Metastases in Melanoma. N Engl J Med 380(9):858, 2019. PMID: 30811912.
6. Schvartsman G, Taranto P, Glitza IC, Agarwala SS, Atkins MB, Buzaid AC. Management of metastatic cutaneous melanoma: updates in clinical practice. Ther Adv Med Oncol 11:1758835919851663, 2019. e-Pub 2019. PMID: 31205512.
7. Ferguson SD, Zheng S, Xiu J, Zhou S, Khasraw M, Brastianos PK, Kesari S, Hu J, Rudnick J, Salacz ME, Piccioni D, Huang S, Davies MA, Glitza IC, Heymach JV, Zhang J, Ibrahim NK, DeGroot JF, McCarty J, O'Brien BJ, Sawaya R, Verhaak RGW, Reddy SK, Priebe W, Gatalica Z, Spetzler D, Heimberger AB. Profiles of Brain Metastases: Prioritization of Therapeutic Targets. Int J Cancer 143(11):3019-3026, 2018. e-Pub 2018. PMID: 29923182.
8. Amaria RN, Reddy SM, Tawbi HA, Davies MA, Ross MI, Glitza IC, Cormier JN, Lewis C, Hwu WJ, Hanna E, Diab A, Wong MK, Royal R, Gross N, Weber R, Lai SY, Ehlers R, Blando J, Milton DR, Woodman S, Kageyama R, Wells DK, Hwu P, Patel SP, Lucci A, Hessel A, Lee JE, Gershenwald J, Simpson L, Burton EM, Posada L, Haydu L, Wang L, Zhang S, Lazar AJ, Hudgens CW, Gopalakrishnan V, Reuben A, Andrews MC, Spencer CN, Prieto V, Sharma P, Allison J, Tetzlaff MT, Wargo JA. Neoadjuvant immune checkpoint blockade in high-risk resectable melanoma. Nat Med 24(11):1649-1654, 2018. e-Pub 2018. PMID: 30297909.
9. Chen WS, Tetzlaff MT, Diwan H, Jahan-Tigh R, Diab A, Nelson K, Glitza IC, Kaunitz GJ, Johnson D, Torres-Cabala C, Pacha O, Taube JM, Maloney K, Prieto VG, Curry JL. Suprabasal acantholytic dermatologic toxicities associated checkpoint inhibitor therapy: A spectrum of immune reactions from paraneoplastic pemphigus-like to Grover-like lesions. J Cutan Pathol 45(10):764-773, 2018. e-Pub 2018. PMID: 29943453.
10. Johnson DH, Zobniw CM, Trinh VA, Ma J, Bassett RL, Abdel-Wahab N, Anderson J, Davis JE, Joseph J, Uemura M, Noman A, Abu-Sbeih H, Yee C, Amaria R, Patel S, Tawbi H, Glitza IC, Davies MA, Wong MK, Woodman S, Hwu WJ, Hwu P, Wang Y, Diab A. Infliximab associated with faster symptom resolution compared with corticosteroids alone for the management of immune-related enterocolitis. J Immunother Cancer 6(1):103, 2018. e-Pub 2018. PMID: 30305177.
11. Glitza IC, Reddy ST, Patel SP. Leptomeningeal disease in uveal melanoma: a case series. J Neurooncol 139(2):503-505, 2018. e-Pub 2018. PMID: 29704079.
12. Forget MA, Haymaker C, Hess KR, Meng YJ, Creasy C, Karpinets T, Fulbright OJ, Roszik J, Woodman SE, Kim YU, Sakellariou-Thompson D, Bhatta A, Wahl A, Flores E, Thorsen ST, Tavera RJ, Ramachandran R, Gonzalez AM, Toth CL, Wardell S, Mansaray R, Patel V, Carpio DJ, Vaughn C, Farinas CM, Velasquez PG, Hwu WJ, Patel SP, Davies MA, Diab A, Glitza IC, Tawbi H, Wong MK, Cain S, Ross MI, Lee JE, Gershenwald JE, Lucci A, Royal R, Cormier JN, Wargo JA, Radvanyi LG, Torres-Cabala CA, Beroukhim R, Hwu P, Amaria RN, Bernatchez C. Prospective analysis of adoptive TIL therapy in patients with metastatic melanoma: response, impact of anti-CTLA4, and biomarkers to predict clinical outcome. Clin Cancer Res 24(18):4416-4428, 2018. e-Pub 2018. PMID: 29848573.
13. Kuske M, Rauschenberg R, Garzarolli M, Meredyth-Stewart M, Beissert S, Troost EGC, Glitza IC, Meier F. Melanoma Brain Metastases: Local Therapies, Targeted Therapies, Immune Checkpoint Inhibitors and Their Combinations-Chances and Challenges. Am J Clin Dermatol 19(4):529-541, 2018. e-Pub 2018. PMID: 29417399.
14. Trinidad C, Nelson KC, Glitza IC, Torres-Cabala CA, Nagarajan P, Tetzlaff MT, Ivan D, Hwu WJ, Prieto VG, Curry JL, Aung PP. Dermatologic toxicity from immune checkpoint blockade therapy with an interstitial granulomatous pattern. J Cutan Pathol 45(7):504-507, 2018. e-Pub 2018. PMID: 29633300.
15. Ballester LY, Glitza IC, Douse DY, Chen MM, Lan C, Haydu LE, Huse JT, Roy-Chowdhuri S, Luthra R, Wistuba II, Davies MA. Evaluating Circulating Tumor DNA From the Cerebrospinal Fluid of Patients with Melanoma and Leptomeningeal Disease. J Neuropathol Exp Neurol 77(7):628-635, 2018. e-Pub 2018. PMID: 29873738.
16. Glitza IC, Schvartsman G, Tawbi H. Advances in the systemic treatment of melanoma brain metastases. Ann Oncol 29(7):1509-1520, 2018. e-Pub 2018. PMID: 29790899.
17. Sakamuri D, Glitza IC, Betancourt Cuellar SL, Subbiah V, Fu S, Tsimberidou AM, Wheler JJ, Hong DS, Naing A, Falchook GS, Fanale MA, Cabanillas ME, Janku F. Phase 1 dose-escalation study of anti CTLA-4 antibody ipilimumab and lenalidomide in patients with advanced cancers. Mol Cancer Ther 17(3):671-676, 2018. e-Pub 2017. PMID: 29237802.
18. Amaria RN, Prieto PA, Tetzlaff MT, Reuben A, Andrews MC, Ross MI, Glitza IC, Cormier J, Hwu WJ, Tawbi HA, Patel SP, Lee JE, Gershenwald JE, Spencer CN, Gopalakrishnan V, Bassett R, Simpson L, Mouton R, Hudgens CW, Zhao L, Zhu H, Cooper ZA, Wani K, Lazar A, Hwu P, Diab A, Wong MK, McQuade JL, Royal R, Lucci A, Burton EM, Reddy S, Sharma P, Allison J, Futreal PA, Woodman SE, Davies MA, Wargo JA. Neoadjuvant plus adjuvant dabrafenib and trametinib versus standard of care in patients with high-risk, surgically resectable melanoma: a single-centre, open-label, randomized, phase 2 trial. Lancet Oncol 19(2):181-193, 2018. e-Pub 2018. PMID: 29361468.
19. Gopalakrishnan V, Spencer CN, Nezi L, Reuben A, Andrews MC, Karpinets TV, Prieto PA, Vicente D, Hoffman K, Wei SC, Cogdill AP, Zhao L, Hudgens CW, Hutchinson DS, Manzo T, Petaccia de Macedo M, Cotechini T, Kumar T, Chen WS, Reddy SM, Szczepaniak Sloane R, Galloway-Pena J, Jiang H, Chen PL, Shpall EJ, Rezvani K, Alousi AM, Chemaly RF, Shelburne S, Vence LM, Okhuysen PC, Jensen VB, Swennes AG, McAllister F, Marcelo Riquelme Sanchez E, Zhang Y, Le Chatelier E, Zitvogel L, Pons N, Austin-Breneman JL, Haydu LE, Burton EM, Gardner JM, Sirmans E, Hu J, Lazar AJ, Tsujikawa T, Diab A, Tawbi H, Glitza IC, Hwu WJ, Patel SP, Woodman SE, Amaria RN, Davies MA, Gershenwald JE, Hwu P, Lee JE, Zhang J, Coussens LM, Cooper ZA, Futreal PA, Daniel CR, Ajami NJ, Petrosino JF, Tetzlaff MT, Sharma P, Allison JP, Jenq RR, Wargo JA. Gut microbiome modulates response to anti-PD-1 immunotherapy in melanoma patients. Science 359(6371):97-103, 2018. e-Pub 2017. PMID: 29097493.
20. Glitza IC, Rohlfs M, Guha-Thakurta N, Bassett RL, Bernatchez C, Diab A, Woodman SE, Yee C, Amaria RN, Patel SP, Tawbi H, Wong M, Hwu WJ, Hwu P, Heimberger A, McCutcheon IE, Papadopoulos N, Davies MA. Retrospective review of metastatic melanoma patients with leptomeningeal disease treated with intrathecal interleukin-2. ESMO Open 3(1):e000283, 2018. e-Pub 2018. PMID: 29387478.
21. Glitza IC, Alqusairi R. Immunotherapy for Melanoma. Adv Exp Med Biol 995:43-63, 2018. PMID: 30539505.
22. Glitza IC, Guha-Thakurta N, D'Souza NM, Amaria RN, McGovern SL, Rao G, Li J. Bevacizumab as an effective treatment for radiation necrosis after radiotherapy for melanoma brain metastases. Melanoma Res 27(6):580-584, 2017. e-Pub 2017. PMID: 28817446.
23. An Y, Jiang W, Kim BYS, Qian JM, Tang C, Fang P, Logan J, D'Souza NM, Haydu LE, Wang XA, Hess KR, Kluger H, Glitza IC, Mahajan A, Welsh JW, Lin SH, Yu JB, Davies MA, Hwu P, Sulman EP, Brown PD, Chiang VLS, Li J. Stereotactic radiosurgery of early melanoma brain metastases after initiation of anti-CTLA-4 treatment is associated with improved intracranial control. Radiother Oncol 125(1):80-88, 2017. e-Pub 2017. PMID: 28916225.
24. Westphal D, Glitza IC, Niessner H. Molecular insights into melanoma brain metastases. Cancer 123(S11):2163-2175, 2017. PMID: 28543697.
25. Cox VL, Bhosale P, Varadhachary GR, Wagner-Bartak N, Glitza IC, Gold KA, Atkins JT, Soliman PT, Hong DS, Qayyum A. Cancer Genomics and Important Oncologic Mutations: A Contemporary Guide for Body Imagers. Radiology 283(2):314-340, 2017. PMID: 28418819.
26. Fang P, Jiang W, Glitza IC, Guha N, Hwu P, Phan J, Mahajan A, Tawbi H, Li J. Radiation necrosis with stereotactic radiosurgery combined with CTLA-4 blockade and PD-1 inhibition for treatment on intracranial disease in metastatic melanoma. J Neurooncology, 2017. e-Pub 2017. PMID: 28500560.
27. Glitza IC, Bucheit A. Clinical Response of Central Nervous System Melanoma to Anti-PD1 Therapy in 2 Melanoma Patients. Scientific Journal of Immunology, 2017. e-Pub 2017.
28. Roh W, Chen PL, Reuben A, Spencer CN, Prieto PA, Miller JP, Gopalakrishnan V, Wang F, Cooper ZA, Reddy SM, Gumbs C, Little L, Chang Q, Chen WS, Wani K, De Macedo MP, Chen E, Austin-Breneman JL, Jiang H, Roszik J, Tetzlaff MT, Davies MA, Gershenwald JE, Tawbi H, Lazar AJ, Hwu P, Hwu WJ, Diab A, Glitza IC, Patel SP, Woodman SE, Amaria RN, Prieto VG, Hu J, Sharma P, Allison JP, Chin L, Zhang J, Wargo JA, Futreal PA. Integrated molecular analysis of tumor biopsies on sequential CTLA-4 and PD-1 blockade reveals markers of response and resistance. Sci Transl Med 9(379), 2017. PMID: 28251903.
29. Chakravarti N, Ivan D, Trinh VA, Glitza IC, Curry JL, Torres-Cabala C, Tetzlaff MT, Bassett RL, Prieto VG, Hwu WJ. High cytotoxic T-lymphocyte-associated antigen 4 and phospho-Akt expression in tumor samples predicts poor clinical outcomes in ipilimumab-treated melanoma patients. Melanoma Res 27(1):24-31, 2017. e-Pub 2016. PMID: 27768639.
30. Glitza IC, Tawbi H, Davies MA. Melanoma Brain Metastases: Current Areas of Investigation and Future Directions. Cancer J 23(1):68-74, 2017. PMID: 28114258.
31. Reuben A, Spencer CN, Prieto PA, Gopalakrishnan V, Reddy SM, Miller JP, Mao X, De Macedo MP, Chen J, Song X, Jiang H, Chen PL, Beird HC, Garber HR, Roh W, Wani K, Chen E, Haymaker C, Forget MA, Little LD, Gumbs C, Thornton RL, Hudgens CW, Chen WS, Austin-Breneman J, Sloane RS, Nezi L, Cogdill AP, Bernatchez C, Roszik J, Hwu P, Woodman SE, Chin L, Tawbi H, Davies MA, Gershenwald JE, Amaria RN, Glitza IC, Diab A, Patel SP, Hu J, Lee JE, Grimm EA, Tetzlaff MT, Lazar AJ, Wistuba II, Clise-Dwyer K, Carter BW, Zhang J, Futreal PA, Sharma P, Allison JP, Cooper ZA, Wargo JA. Genomic and immune heterogeneity are associated with differential responses to therapy in melanoma. NPJ Genom Med 2, 2017. e-Pub 2017. PMID: 28819565.
32. Cohen JV, Tawbi H, Margolin KA, Amravadi R, Bosenberg M, Brastianos PK, Chiang VL, de Groot J, Glitza IC, Herlyn M, Holmen SL, Jilaveanu LB, Lassman A, Moschos S, Postow MA, Thomas R, Tsiouris JA, Wen P, White RM, Turnham T, Davies MA, Kluger HM. Melanoma Central Nervous System Metastases: Current Approaches, Challenges, and Opportunities. Pigment Cell Melanoma Res 29(6):627-642, 2016. e-Pub 2016. PMID: 27615400.
33. Jour G, Glitza IC, Ellis RM, Torres-Cabala CA, Tetzlaff MT, Li JY, Nagarajan P, Huen A, Aung PP, Ivan D, Drucker CR, Prieto VG, Rapini RP, Patel A, Curry JL. Autoimmune Dermatologic Toxicities from Immune Checkpoint Blockade with anti-PD-1 Antibody Therapy: A Report on Bullous Skin Eruptions. J Cutan Pathol 43(8):688-96, 2016. e-Pub 2016. PMID: 27086658.
34. Chen G, McQuade JL, Panka DJ, Hudgens CW, Amin-Mansour A, Mu XJ, Bahl S, Jané-Valbuena J, Wani KM, Reuben A, Creasy CA, Jiang H, Cooper ZA, Roszik J, Bassett RL, Joon AY, Simpson LM, Mouton RD, Glitza IC, Patel SP, Hwu WJ, Amaria RN, Diab A, Hwu P, Lazar AJ, Wargo JA, Garraway LA, Tetzlaff MT, Sullivan RJ, Kim KB, Davies MA. Clinical, Molecular, and Immune Analysis of Dabrafenib-Trametinib Combination Treatment for BRAF Inhibitor-Refractory Metastatic Melanoma: A Phase 2 Clinical Trial. JAMA Oncol 2(8):1056-64, 2016. e-Pub 2016. PMID: 27124486.
35. Chen PL, Roh W, Reuben A, Cooper ZA, Spencer CN, Prieto PA, Miller JP, Bassett RL, Gopalakrishnan V, Wani K, De Macedo MP, Austin-Breneman JL, Jiang H, Chang Q, Reddy SM, Chen WS, Tetzlaff MT, Broaddus RJ, Davies MA, Gershenwald JE, Haydu L, Lazar AJ, Patel SP, Hwu P, Hwu WJ, Diab A, Glitza IC, Woodman SE, Vence LM, Wistuba II, Amaria RN, Kwong LN, Prieto V, Davis RE, Ma W, Overwijk WW, Sharpe AH, Hu J, Futreal PA, Blando J, Sharma P, Allison JP, Chin L, Wargo JA. Analysis of immune signatures in longitudinal tumor samples yields insight into biomarkers of response and mechanisms of resistance to immune checkpoint blockade. Cancer Discov 6(8):827-37, 2016. e-Pub 2016. PMID: 27301722.
36. Cooper ZA, Reuben A, Spencer CN, Prieto PA, Austin-Breneman JL, Jiang H, Haymaker C, Gopalakrishnan V, Tetzlaff MT, Frederick DT, Sullivan RJ, Amaria RN, Patel SP, Hwu P, Woodman SE, Glitza IC, Diab A, Vence LM, Rodriguez-Canales J, Parra ER, Wistuba II, Coussens LM, Sharpe AH, Flaherty KT, Gershenwald JE, Chin L, Davies MA, Clise-Dwyer K, Allison JP, Sharma P, Wargo JA. Distinct clinical patterns and immune infiltrates are observed at time of progression on targeted therapy versus immune checkpoint blockade for melanoma. Oncoimmunology 5(3):e1136044, 2016. e-Pub 2016. PMID: 27141370.
37. Peng W, Chen JQ, Liu C, Malu S, Creasy C, Tetzlaff MT, Xu C, McKenzie JA, Zhang C, Liang X, Williams LJ, Deng W, Chen G, Mbofung R, Lazar AJ, Torres-Cabala CA, Cooper ZA, Chen PL, Tieu TN, Spranger S, Yu X, Bernatchez C, Forget MA, Haymaker C, Amaria R, McQuade JL, Glitza IC, Cascone T, Li HS, Kwong LN, Heffernan TP, Hu J, Bassett RL, Bosenberg MW, Woodman SE, Overwijk WW, Lizée G, Roszik J, Gajewski TF, Wargo JA, Gershenwald JE, Radvanyi L, Davies MA, Hwu P. Loss of PTEN promotes resistance to T cell-mediated immunotherapy. Cancer Discov 6(2):202-16, 2016. e-Pub 2015. PMID: 26645196.
38. Zachary A. Cooper, Alexandre Reuben, Christine N. Spencer, Peter A. Prieto, Jacob L. Austin-Breneman, Hong Jiang, Cara Haymaker, Vancheswaran Gopalakrishnan, Michael T. Tetzlaff, Dennie T. Frederick, Ryan J. Sullivan, Rodabe N. Amaria, Sapna P. Patel, Patrick Hwu, Scott E. Woodman, Glitza IC, Adi Diab, Luis M. Vence, Jaime Rodriguez-Canales, Edwin R. Parra, Ignacio I. Wistuba, Lisa M. Coussens, Arlene H. Sharpe, Keith T. Flaherty, Jeffrey E. Gershenwald, Lynda Chin, Michael A. Davies, Karen Clise-Dwyer, James P. Allison, Padmanee Sharma & Jennifer A. Wargo. Distinct clinical patterns and immune infiltrates are observed at time of progression on targeted therapy versus immune checkpoint blockade for melanoma. Oncoimmunology, 2016.
39. Glitza IC, Haymaker C, Bernatchez C, Vence L, Rohlfs M, Richard J, Lacey C, Mansaray R, Fulbright OJ, Ramachandran R, Toth C, Wardell S, Patel SP, Woodman SE, Hwu WJ, Radvanyi LG, Davies MA, Papadopoulos NE, Hwu P. Intrathecal administration of tumor-infiltrating lymphocytes is well tolerated in a patient with leptomeningeal disease from metastatic melanoma: A case report. Cancer Immunol Res 3(11):1201-6, 2015. e-Pub 2015. PMID: 26216417.
40. Glitza IC, Lu G, Shah R, Bashir Q, Shah N, Champlin RE, Shah J, Orlowski RZ, Qazilbash MH. Chromosome 8q24.1/c-MYC Abnormality: A Marker for High-Risk Myeloma. Leuk Lymphoma 56(3):1-18, 2015. e-Pub 2014. PMID: 24844357.
41. Glitza IC, Davies MA. Genotyping of cutaneous melanoma. Chin Clin Oncol 3(3):1-16, 2014. PMID: 25632386.
42. Lu G, Muddasani R, Orlowski RZ, Abruzzo LV, Qazilbash MH, You MJ, Wang Y, Zhao M, Chen S, Glitza IC, Medeiros LJ. Plasma cell enrichment enhances detection of high-risk cytogenomic abnormalities by fluorescence in situ hybridization and improves risk stratification of patients with plasma cell neoplasms. Arch Pathol Lab Med 137(5):625-31, 2013. PMID: 23627452.
43. Hui D, Glitza IC, Chisholm G, Yennu S, Bruera E. Attrition rates, reasons, and predictive factors in supportive care and palliative oncology clinical trials. Cancer 119(5):1098-105, 2013. e-Pub 2012. PMID: 23132290.
44. Glitza IC, Ehrhard I, Müller-Pebody B, Reintjes R, Breuer T, Ammon A, Sonntag HG. Longitudinal study of meningococcal carrier rates in teenagers. Int J Hyg Environ Health 211(3-4):263-72, 2008. e-Pub 2007. PMID: 17981083.
45. Amaria RN, Reddy SM, Tawbi HA, Davies MA, Ross MI, Glitza IC, Cormier JN, Lewis C, Hwu WJ, Hanna E, Diab A, Wong MK, Royal R, Gross N, Weber R, Lai SY, Ehlers R, Blando J, Milton DR, Woodman S, Kageyama R, Wells DK, Hwu P, Patel SP, Lucci A, Hessel A, Lee JE, Gershenwald J, Simpson L, Burton EM, Posada L, Haydu L, Wang L, Zhang S, Lazar AJ, Hudgens CW, Gopalakrishnan V, Reuben A, Andrews MC, Spencer CN, Prieto V, Sharma P, Allison J, Tetzlaff MT, Wargo JA. Author Correction: Neoadjuvant immune checkpoint blockade in high-risk resectable melanoma. Nat Med. e-Pub 2018. PMID: 30361510.
46. Vishnoi M, Boral D, Liu H, Sprouse ML, Yin W, Goswami-Sewell D, Tetzlaff MT, Davies MA, Glitza IC, Marchetti D. Targeting USP7 identifies a metastasis-compotent state within bone marrow-resident melanoma CTCs. Cancer Research. e-Pub 2018. PMID: 30026332.
47. Glitza IC, Tawbi HA. "Liquid Gold"- The unTAPped potential of cerebrospinal fluid analysis?. Clin Cancer Res. e-Pub 2020. PMID: 32139404.
48. Glitza IC, Smalley KSM, Brastianos PK, Davies MA, McCutcheon I, Liu JKC, Ahmed KA, Arrington JA, Evernden BR, Smalley I, Eroglu Z, Khushalani N, Margolin K, Kluger H, Atkins MB, Tawbi H, Boire A, Forsyth P. Leptomeningeal disease in melanoma patients: An update to treatment, challenges, and future directions. Pigment Cell Melanoma Res. e-Pub 2020. PMID: 31916400.
49. Lucci A, Hall C, Patel SP, Narendran B, Bauldry JB, Royal R, Karhade M, Upshaw JR, Wargo JA, Glitza IC, Wong MKK, Amaria RN, Tawbi HA, Diab A, Davies MA, Gershenwald JE, Lee JE, Hwu P, Ross MI. Circulating tumor cells and early relapse in node-positive melanoma. Clin Cancer Res. e-Pub 2020. PMID: 32015020.
50. Haydu LE, Lo SN, McQuade JL, Amaria RN, Wargo J, Ross MI, Cormier JN, Lucci A, Lee JE, Ferguson SD, Saw RPM, Spillane AJ, Shannon KF, Stretch JR, Hwu P, Patel SP, Diab A, Wong MKK, Glitza Oliva IC, Tawbi H, Carlino MS, Menzies AM, Long GV, Lazar AJ, Tetzlaff MT, Scolyer RA, Gershenwald JE, Thompson JF, Davies MA. Cumulative Incidence and Predictors of CNS Metastasis for Patients With American Joint Committee on Cancer 8th Edition Stage III Melanoma. J Clin Oncol:JCO1901508. e-Pub 2020. PMID: 31990608.
51. Schvartsman G, Ma J, Bassett RL, Haydu LE, Amaria RN, Hwu P, Wong MK, Hwu WJ, Diab A, Patel SP, Davies MA, Hamerschlak N, Tawbi HA, Glitza Oliva IC. Incidence, patterns of progression, and outcomes of preexisting and newly discovered brain metastases during treatment with anti-PD-1 in patients with metastatic melanoma. Cancer. e-Pub 2019. PMID: 31398264.
52. Ferguson SD, Bindal S, Bassett RL, Haydu LE, McCutcheon IE, Heimberger AB, Li J, O'Brien BJ, Guha-Thakurta N, Tetzlaff MT, Tawbi H, Davies MA, Glitza IC. Predictors of survival in metastatic melanoma patients with leptomeningeal disease (LMD). J Neurooncol. e-Pub 2019. PMID: 30847840.
53. Fischer GM, Jalali A, Kircher DA, Lee WC, McQuade JL, Haydu LE, Joon AY, Reuben A, de Macedo MP, Carapeto FCL, Yang C, Srivastava A, Ambati CR, Sreekumar A, Hudgens CW, Knighton B, Deng W, Ferguson SD, Tawbi HA, Glitza IC, Gershenwald JE, Vashisht Gopal YN, Hwu P, Huse JT, Wargo JA, Futreal PA, Putluri N, Lazar AJ, DeBerardinis RJ, Marszalek JR, Zhang J, Holmen SL, Tetzlaff MT, Davies MA. Molecular Profiling Reveals Unique Immune and Metabolic Features of Melanoma Brain Metastases. Cancer Discov. e-Pub 2019. PMID: 30787016.
54. Pires da Silva I, Glitza IC, Haydu LE, Johnpulle R, Banks PD, Grass GD, Goldinger SMA, Smith JL, Everett AS, Koelblinger P, Roberts-Thomson R, Millward M, Atkinson VG, Guminski A, Kapoor R, Conry RM, Carlino MS, Wang W, Shackleton MJ, Eroglu Z, Lo S, Hong AM, Long GV, Johnson DB, Menzies AM. Incidence, features and management of radionecrosis in melanoma patients treated with cerebral radiotherapy and anti-PD-1 antibodies. Pigment Cell Melanoma Res. e-Pub 2019. PMID: 30767428.
55. Eroglu Z, Holmen SL, Chen Q, Khushalani NI, Amaravadi R, Thomas R, Ahmed KA, Tawbi H, Chandra S, Markowitz J, Smalley I, Liu JKC, Chen YA, Najjar YG, Karreth FA, Abate-Daga D, Glitza IC, Sosman JA, Sondak VK, Bosenberg M, Herlyn M, Atkins MB, Kluger H, Margolin K, Forsyth PA, Davies MA, Smalley KSM. Melanoma central nervous system metastases: An update to approaches, challenges, and opportunities. Pigment Cell Melanoma Res. e-Pub 2019. PMID: 30712316.
56. Amaria RN, Reddy SM, Tawbi HA, Davies MA, Ross MI, Glitza IC, Cormier JN, Lewis C, Hwu WJ, Hanna E, Diab A, Wong MK, Royal R, Gross N, Weber R, Lai SY, Ehlers R, Blando J, Milton DR, Woodman S, Kageyama R, Wells DK, Hwu P, Patel SP, Lucci A, Hessel A, Lee JE, Gershenwald J, Simpson L, Burton EM, Posada L, Haydu L, Wang L, Zhang S, Lazar AJ, Hudgens CW, Gopalakrishnan V, Reuben A, Andrews MC, Spencer CN, Prieto V, Sharma P, Allison J, Tetzlaff MT, Wargo JA. Publisher Correction: Neoadjuvant immune checkpoint blockade in high-risk resectable melanoma. Nat Med. e-Pub 2018. PMID: 30361511.

Abstracts

1. Gopalakrishnan V, Spencer C, McQuade J, Andrews M, Helmink B, Cogdill A, Sirmans E, Haydu L, Posada E, Burton E, Glitza IC, Amaria R, Patel S, Diab A, Wong M, Tawbi H, Hwu WJ, Davies M, Hwu P, Jeng R, Nelson K, Daniel-MacDougall C, Cohen L, Wargo J. The gut microbiome of metastatic melanoma patients initiating systemic therapy is influenced by host factors including diet, probiotic and antibiotic use. SITC 2018, 2018.
2. Helmink B, Gopalakrishnan V, Khan A, Gaudreau PO, Sirmans E, Burton E, Jensen V, Duran A, Martin L, Harris A, Miles A, McQuade J, Cogdill A, Spencer C, Arora R, Ajami N, Petrosino J, Mohamed J, Patel S, Wong M, Amaria R, Gershenwald J, Hwu P, Hwu WJ, Davies M, Glitza IC, Tawbi H, Marnellos G, Sceneay J, Wortman J, Jayaraman L, Cook D, LaValle T, Jenq R, Heffernan T, Wargo J. Variation of the gut microbiome of complete responders to immune checkpoint blockade and healthy individuals- implications for clinical trial design. SITC 2018, 2018.
3. Bentebibel S, Johnson D, Lecagoonporn S, Haymaker C, Safa H, Yee C, Amaria R, Patel S, Tawbi H, Glitza IC, Davies M, Wong M, Hwu WJ, Hwu P, Overwijk W, Trifan O, Bernatchez C, Diab A. Phase 1/2 study of image guided intratumoral CD40 agonistic monoclonal antibody (APX005M) in combination with systemic pembrolizumab for treatment-naive metastatic melanoma. SITC 2018, 2018.
4. Glitza IC, Rohlfs ML, Iqbal M, Richard J, Burton E, Duncan S, Brown C, Anderson J, Hwu P, Hwu WJ, Yee C, Patel S, Woodman S, Amaria R, Diab A, Tawbi H, Davies M. A phase I/Ib study of concurrent intravenous (IV) and intrathecal (IT) nivolumab (NIVO) for melanoma patients (pts) with Leptomeningeal disease (LMD). Annals of Oncology 29(8), 2018.
5. McQuade JL, Gopalakrishnan V, Spencer C, Andrews MC, Helmink B, Cogdill AP, Sirmans E, Haydu L, Posada E, Burton E. Glitza IC, Amaria R, Patel S, Diab A, Wong M, Tawbi H, Hwu WJ, Davies MA, Hwu P, Jenq R, Nelson K, Daniel CR, Cohen L, Wargo J. The gut microbiome of melanoma patients is distinct from that of health individuals and is impacted by probiotic and antibiotic use. Melanoma Congress 2018 _SMR, 2018.
6. Glitza IC, Schvartsman G, Tawbi H. Advances in the systemic treatment of melanoma brain metastases. ESMO 2018 Annals of Oncology, 2018.
7. Scutti JA, Vence LM, Royal RE, Wray TC, Cormier JN, Lee JE, Lucci A, Gershenwald JE, Ross MI, Wargo JA, Millerchip K, Amaria RN, Davies MA, Diab A, Glitza IC, Hwu WJ, Patel S, Woodman SE, Overwijk WE, Hwu P. Resiquimod, a toll like receptor agonist promotes melanoma regression by enhancing plasmacytoid dendritic cells and T cytotoxic activity as a vaccination adjuvant and by direct tumor application. AACR Annual Meeting, 2018.
8. Keung EZ, Glitza IC, Burton E, Amaria RN, Patel SP, Diab A, Yee C, Wong MK, Hwu WJ, Hwu P, Woodman SE, Tetzlaff MT, Trujillo-Conley N, Milton DR, Davies MA, Rai K, Fernandez I, Blanco JM, Vence LM, Sharma P, Allison JP, Wargo JA, Tawbi H. The impact of combination oral azacitidine (CC-486) + pembrolizumab (PEMBRO) on the immune infiltrate in metastatic melanoma (MM). AACR Annual Meeting 2018, 2018.
9. Amaria RN, Trinh V, Gu J, McIntyre S, Torres C, Simien R, Diab A, Tawbi H, Davies MA, Wong MK, Hwu P, Glitza IC, Patel SP, Hwu WJ. Treatment strategies using anti-PD1\PD-L1 (anti-PD) and BRAF/MEK inhibitor (BRAFi) therapy: a retrospective study comparing sequential vs. concurrent administration in BRAF-mutated metastatic melanoma (BMMM). AACR Annual Meeting 2018, 2018.
10. Reuben A, Spencer CN, Prieto PA, Gopalakrishnan V, Reddy SM, Miller JP, Mao X, De Macedo MP, Chen J, Song X, Jiang H, Chen Pl, Beird HC, Garber HC, Roh W, Wani K, Chen E, Haymaker C, Forget MA, Little LD, Gumbs C, Thornton RL, Hudgens CW, Chen WS, Austin-Breneman J, Sloane RS, Nezi L, Cogdill AP, Bernatchez C, Roszik J, Hwu P, Woodman SE, Chin L, Tawbi H, Davies MA, Gershenwald JE, Amaria R, Glitza IC, Diab A, Patel SP, Hu J, Lee JE, Grimm E, Tetzlaff MT, Lazar AJ, Wistuba II, Clise-Dwyer K, Carter BW, Zhang J, Futreal PA, Sharma P, Allison JP, Cooper ZA, Wargo JA. Genomic and immune heterogeneity are associated with differential responses to therapy in melanoma, 2017. e-Pub 2017.
11. Glitza IC, Tawbi H, Davies MA. Melanoma Brain Metastases: Current Areas of Investigation and Future Directions. Cancer Journal, 2017. e-Pub 2017.
12. Weiyi Peng, Jie Qing Chen, Chengwen Liu, Shruti Malu, Caitlin Creasy, Michael Tetzlaff, Chunyu Xu, Jodi McKenzie, Chunlei Zhang, Xiaoxuan Liang, Leila Williams, Wanleng Deng, Guo Chen, Rina Mbofung, Alexander Lazar, Carlos Torres-Cabala, Zachary Cooper, Pei-Ling Chen, Trang Tieu, Stefani Spranger, Xiaoxing Yu, Chantale Bernatchez, Marie-Andree Forget, Cara Haymaker, Rodabe Amaria, Jennifer McQuade, Glitza IC, Tina Cascone, Haiyan Li, Lawrence Kwong, Timothy Heffernan, Jianhua Hu, Roland Bassett, Marcus Bosenberg, Scott Woodman, Willem Overwijk, Gregory Lizée, Jason Roszik, Thomas Gajewski, Jennifer Wargo, Jeffrey Gershenwald, Laszlo Radvanyi, Michael Davies, Patrick Hwu. Loss of PTEN promotes resistance to T cell-mediated immunotherapy. AACR Annual Meeting 2016, 2016. e-Pub 2016.
13. Edelyn Barcena, VanAnh Trinh, Susan E McIntyre, Rinata Simien, Suzanne Cain, Adi Diab, Rodabe Navroze Amaria, Sapna Pradyuman Patel, Glitza IC, Hussein Abdul-Hassan Tawbi, Michael A. Davies, Wen-Jen Hwu. Responses in patients with BRAF V600-mutant metastatic melanoma receiving anti-PD1/PDL1 therapy alone or combined with BRAF inhibitors. ASCO 2016, 2016. e-Pub 2016.
14. Andrew Cota Shaw, VanAnh Trinh, Roland L. Bassett, Glitza IC, Adi Diab, Rodabe Navroze Amaria, Hussein Abdul-Hassan Tawbi, Michael A. Davies, Wen-Jen Hwu, Patrick Hwu, Sapna Pradyuman Patel. Retrospective analysis of safety and efficacy of ipilimumab in elderly patients with advanced melanoma. 2016 ASCO Annual Meeting, 2016. e-Pub 2016.
15. Michelle Rohlfs, Roland L. Bassett, Carol Lacey, Natalie McQuail, Urvi Mehta, Ida John, Rinata Simien, Stephanie Tupue, Tina Karin Dett, Glitza IC, Adi Diab, Rodabe Navroze Amaria, Hussein Abdul-Hassan Tawbi, Michael A. Davies, Wen-Jen Hwu, Patrick Hwu, Sapna Pradyuman Patel. BRAF with or without MEK inhibition plus PD-1 checkpoint blockade for the treatment of metastatic melanoma. 2016 ASCO Annual Meeting, 2016. e-Pub 2016.
16. Rodabe Navroze Amaria, Cara L. Haymaker, Chantale Bernatchez, Marie-Andree Forget, Vruti Patel, Wen-Jen Hwu, Michael A. Davies, Sapna Pradyuman Patel, Adi Diab, Glitza IC, Hussein Abdul-Hassan Tawbi, Scott Eric Woodman, Jennifer Ann Wargo, Merrick I. Ross, Jeffrey Edwin Lee, Jeffrey E. Gershenwald, Janice N. Cormier, Richard Eldon Royal, Anthony Lucci, Patrick Hwu. A phase I/II study of lymphodepletion plus adoptive cell transfer (ACT) with T cells transduced with CXCR2 and NGFR followed by high dose interleukin-2 (IL-2) in patients with metastatic melanoma (MM). ASCO Annual Meeting 2016, 2016. e-Pub 2016.
17. Dae Won Kim, Cara Haymaker, Natalie McQuail, Elizabeth Sirmans, Christine Spencer, Glitza IC, Rodabe Amaria, Scott Woodman, Sapna Patel, Michael Davies, Cassian Yee, Wen-Jen Hwu, Chantale Bernatchez, Jennifer Wargo, Padmanee Sharma, James Allison, Patrick Hwu, Alda Tam, Adi Diab. Pilot study of intratumoral (IT) cryoablation (cryo) in combination with systemic checkpoint blockade in patients with metastatic melanoma (MM). Journal for ImmunoTherapy of Cancer 2015, 2016. e-Pub 2016.
18. McQuade J, Guo C, Panka D, Reuben A, Bassett R, Joon a, Lazar A, Tetzlaff M, Simpson L, Mouton R, Glitza IC, Patel S, Hwu WJ, Amara R, Diab A, Hwu P, Wargo JA, Sullivan R, Kim K, Davies M,. Phase II study of dabrafenib (D) and trametinib (T) following progression on BRAF inhibitor (BRAFi): clinical and molecular predictors of response. Society for Melanoma Research, 2015.
19. Kim DW, Haymaker C, McQuail N, Sirmans E, Spencer C, Glitza IC, Amaria R, Woodman S, Patel S, Davies MA, Yee C, Hwu WJ, Bernatchez C, Wargo JA, Sharma P, Allison J, Hwu P, Tam A, Diab A. Pilot Study of intratumoral cryoablation in combination with systemic checkpoint blockade in patients with metastatic melanoma, 2015.
20. Glitza IC M.L. Rohlfs, R. Bassett Jr., I. John, J. Richard, M. Iqbal, T. Bernzen, D.L. Gerber, C. Lacey, A. Diab, R.N. Amaria, S.E. Woodman, S.P. Patel, C. Yee, W.J. Hwu, P. Hwu, N. Papadopoulos, M.A. Davies. Long-term efficacy of intrathecal interleukin‐2 (IT IL2) in metastatic melanoma (MM) patients (pts) with leptomeningeal disease (LMD). ESMO 2015, 2015.
21. Divya Sakamuri, Sonia L. Betancourt Cuellar, Glitza IC, Siqing Fu, Jennifer J. Wheler, Gerald S. Falchook, Apostolia M. Tsimberidou, David S. Hong, Vivek Subbiah, Michelle A. Fanale, Maria E. Cabanillas, Funda Meric-Bernstam, Filip Janku. Phase I study: Ipilimumab (anti CTLA-4) in combination with Lenalidomide in patients with advanced cancers, 2015. e-Pub 2015.
22. Sapna Pradyuman Patel, Sruti Lam, Michelle L. Rohlfs, Patricia S Fox, Jessie Richard, Masood Iqbal, Theresa Bernzen, Glitza IC, Nicholas E. Papadopoulos, Patrick Hwu, Michael A. Davies. BRAF and NRAS mutations in Metastatic Melanoma Patients with Leptomeningeal Disease. ASCO Annual Meeting 2015, 2015. e-Pub 2015.
23. Rodabe Navroze Amaria, Roland L. Bassett, Lauren Simpson, Frances Delaney, Patrick Hwu, Kevin Kim, Wen-Jen Hwu, Sapna Pradyuman Patel, Glitza IC, Michael A. Davies, Scott Eric Woodman, Cassian Yee, Agop Y. Bedikian. Phase I study of ipilimumab (IPI) with biochemotherapy (BCT) for chemonaïve patients with metastatic melanoma (MM). ASCO 2015, 2015. e-Pub 2015.
24. Rodabe Navroze Amaria, Jennifer Ann Wargo, Zachary A Cooper, Michael T. Tetzlaff, Alexandre Reuben, Michael A. Davies, Jeffrey E. Gershenwald, Hong Jiang, Jacob Austin-Breneman, Jeffrey Edwin Lee, Patrick Hwu, Wen-Jen Hwu, Janice N. Cormier, Richard Eldon Royal, Anthony Lucci, Sapna Pradyuman Patel, Adi Diab, Glitza IC, Elizabeth M Burton, Merrick I. Ross. Treatment with neoadjuvant BRAF Inhibition Yields Responses in Patients (pts) with High Risk Borderline Resectable Stage III Melanoma. ASCO 2015, 2015. e-Pub 2015.
25. Jennifer Leigh McQuade, Guo Chen, David J Panka, Alexandre Reuben, Roland L. Bassett, Aron Joon, Alexander J. F. Lazar, Michael T. Tetzlaff, Lauren Simpson, Rosalind Mouton, Sapna Pradyuman Patel, Glitza IC, Wen-Jen Hwu, Rodabe Navroze Amaria, Adi Diab, Patrick Hwu, Jennifer Ann Wargo, Ryan J. Sullivan, Kevin Kim, Michael A. Davies. Phase II study of dabrafenib and trametinib following progression on BRAF inhibitor monotherapy in metastatic melanoma: Exploration of clinical and molecular predictors of response. ASCO 2015, 2015. e-Pub 2015.
26. Jennifer Ann Wargo, Rodabe Navroze Amaria, Merrick I. Ross, Robyn P.M. Saw, Jeffrey E. Gershenwald, Patrick Hwu, Sapna Pradyuman Patel, Glitza IC, Adi Diab, Richard Kefford, Richard A Scolyer, Helen Rizos, John F Thompson, Kerwin Shannon, Andrew Spillane, Matteo S. Carlino, Alex Guminski, Lauren Simpson, Michael A. Davies, Georgina V. Lon. Neoadjuvant BRAF (dabrafenib) and MEK (trametinib) inhibition for high-risk resectable stage III and IV melanoma. ASCO 2015, 2015. e-Pub 2015.
27. Chakravarti N, Glitza IC, Trinh VA, Bassett RL, Hwu WJ, Prieto VG. Biomarker analysis predicts antitumor activity of Ipilimumab therapy in patients with refractory metastatic melanoma. Cancer Research(74), 2014.
28. Glitza IC, Bernatchez C, Bassett RL, Vaugh C, Velasquez P, Diab A, Amaria RN, Yee C, Wood SE, Patel SP, Kim K, Davis MA, Papadopoulos NE, Bedikian AY, Hwu WJ, Radvanyi LG, Hwu P. Treatment with tumor-infiltrating lymphocytes (TIL) in metastatic melanoma and clinical benefit regardless of site of origin, mutation status, or prior checkpoint blockade. Journal of Clinical Oncology 32(5s), 2014.
29. Hui D, Glitza I, Chisholm G, Yennu S, Bruera E. Attrition rates, reasons, and predictive factors in supportive care and palliative oncology clinical trials. Cancer 119(5):1098-105, 2013.
30. Glitza IC, Conter HJ, Turner R, Reddy S, Bruera E. Opinions of Nurses on the application and implications of DNR/DNI orders. ESMO 23(Supplement 9), 2012.
31. Kim DW, Haymaker C, Perdon K, Amaria R, McQuail N, Fa'ak F, Spencer CN, Sirmans E, Glitza IC, Wargo JA, Woodman S, Patel S, Davies M, Hwu WJ, Bernatchez C, Hwu P, Diab A. Phase II trial of nab-paclitaxel (ABI) plus ipilimumab (ipi) in patients with metastatic melanoma (MM). Society for Melanoma Research. e-Pub 2015.
32. Pires Da Silva I, Johnpulle R, Banks P, Grass G, Smith J, Everett Ashlyn, Goldinger S, Roberts-Thomson R, Millward M, Glitza IC, Haydu L, Atkinson V, Wang T, Eroglu Z, Conry R, Shackleton M, Hong A, Long G, Johnson D, Menxies A,. Incidence, features and management of radionecrosis (RN) in melanoma patients (pts) treated with cerebral radiotherapy (RT) and anti-PD-1 antibodies (PD1). ASCO 2017. e-Pub 2017.
33. Chen W, Andrews M, Spencer C, Tawbi H, Lazar A, Tetzlaff M, Patel S, Hwu P, Hwu WJ, Diab A, Glitza IC, Amaria R, Burton E, Woodman S, Davies M, Gershenwald J, Sharma P, Allison J, Futreal A, Wargo J. Molecular and immune predictors of response and toxicity to combined CTLA-4 and PD-1 blockade in metastatic melanoma (MM) patients (pts). ASCO 2017. e-Pub 2017.
34. Wargo J, Amaria R, Prieto P, Andrews M, Tetzlaff M, Futreal A, Hwu P, Hwu WJ, Glitza IC, Tawbi H, Cormier J, Lee J, Patel S, Simpson L, Burton E, Bassett R, Ross M, Gershenwald J, Davies M, Woodman S. Relapse-free survival and target identification to enhance response with neoadjuvant and adjuvant debrafenib+trametinib (D+T) treatment compared to standard-of-care (SOC) surgery in patients (pts) with high-risk resectable BRAF-mutant metastatic melanoma. ASCO 2017. e-Pub 2017.
35. Keung E, Burton E, Amaria R, Glitza IC, Patel S, Diab A, Yee C, Wong M, Hwu WJ, Hwu P, Woodman S, Tetzlaff M, Milton D, Perez K, Davies M, Rai K, Wargo J, Tawbi H. A phase II study of oral azacitidine (CC-486) in combination with pembrolizumab (PEMBRO) in patients with metastatic melanoma (MM). ASCO 2017. e-Pub 2017.
36. Royal R, Vence L, Wray T, Cormier J, Lee J, Gershenwald J, Ross M, Wargo J, Amaria R, Davies M, Diab A, Glitza IC, Hwu WJ, Patel S, Woodman S, Overwijk W, Hwu P. A toll-like receptor agonist to drive melanoma regression as a vaccination adjuvant or by direct tumor application. ASCO 2017. e-Pub 2017.
37. McKean M, Haydu L, Ma J, Bassett R, Hwu WJ, Patel S, Diab A, Glitza IC, Tawbi H, Wong M, McQuade J, Hwu P, Davies M, Amaria R. Prognostic factors for overall survival (OS) in metastatic melanoma (MM) patients (pts) treated with immune checkpoint inhibitors: A single institution study of 696 pts. ASCO 2017. e-Pub 2017.
38. Schvartsman G, Ma J, Bassett R, Haydu L, Amaria R, Hwu P, Hwu WJ, Diab A, Patel S, Davies M, Wabi H, Glitza IC. Incidence, patterns of progression and outcomes of melanoma brain metastasis (MBM) during programmed-death 1 inhibitor (PD1i) therapy. ASCO 2017. e-Pub 2017.
39. Patel S, Glitza IC, Diab A, Amaria R, Davies M, Hwu P, Tawbi H, Hwu WJ,. The safety and early efficacy of high-dose ipilimumab (IPI) and the combination nivolumab plus ipilimumab (NIVO+IPI) in patients (pts) with uveal melanoma (UM). ASCO 2017. e-Pub 2017.
40. Wargo J, Gopalakrishnan V, Spencer C, Karpinets T, Reuben A, Andrews M, Tetzlaff M, Lazar A, Hwu P, Hwu WJ, Glitza IC, Tawbi H, Patel S, Lee J, Davies M, Gershenwald J, Futreal A, Sharma P, Allison J, Jeng R. Association of the diversity and composition of the gut microbiome with responses and survival in metastatic melanoma patients on anti-PD-1 therapy. ASCO 2017. e-Pub 2017.
41. Marc Isamu Uemura, Cara L. Haymaker, Ravi Murthy, Marihella James, Mark Cornfeld, Srinivas Chunduru, Sudhir Agrawal, Cassian Yee, Jennifer A. Wargo, Rodabe Navroze Amaria, Sapna Pradyuman Patel, Hussein Abdul-Hassan Tawbi, Glitza IC, Scott Eric Woodman, Wen-Jen Hwu, Michael A. Davies, Patrick Hwu, Willem W Overwijk, Chantale Bernatchez, Adi Diab. Intratumoral IMO-2125, a TLR9 agonist in combination with ipilimumab in PD-L1 refractory melanoma. e-Pub 2017.
42. Johnson DH, Bentebibel S, Lecagooporn S, Bernatchez C, Haymaker C, Murthy R, Tam A, Yee C, Amaria R, Patel SP, Tawbi H, Glitza IC, Davies MA, Hwu WJ, Hwu P, Overwijk W, Diab A. Phase I/II dose escalation and expansion cohort safety and efficacy study of image guided intratumoral CD40 agonistic monoclonal antibody APX005M in combination with systemic pembrolizumab for treatment naive metastatic melanoma. ASCO Meeting Library. e-Pub 2018.
43. Amaria R, Reddy S, Tawbi H, Davies MA, Ross M, Glitza IC, Cormier J, Lewis C, Hwu WJ, Ehab YH, Diab A, Wong MK, Royal R, Gross N, Weber R, Lai S, Ehlers R, Burton EM, Tetzlaff MT, Wargo JA. Neoadjuvant (neo) immune checkpoint blockade (ICB) in patients (Pts) with high-risk resectable metastatic melanoma (MM). ASCO Meeting Library. e-Pub 2018.
44. Schvartsman G, Ma J, Bassett R, Haydu L, Amaria R, Hwu P, Hwu WJ, Diab A, Patel SP, Wong MK, Woodman SE, Davies MA, Glitza IC, Tawbi H,. Outcomes of metastatic melanoma (MM) patients (pts) after discontinuation of anti-Programmed-Death 1 (PD1) therapy without disease progression. e-Pub 2018.
45. Tawbi H, Peng W, Milton D, Amaria R, Glitza IC, Hwu WJ, Patel SP, Wong MK, Woodman SE, Yee C, McQuade JL, Tetzlaff MT, Lazar AJ, Cain S, Burton EM, Beumer JH, Hwu P, Davies MA. Phase I/II study of the P13K inhibitor GSK2636771 in combination with pembrolizumab (P) in patients (pts) with PD-1 refractory metastatic melanoma (MM) and PTEN loss. ASCO Meeting Library. e-Pub 2018.
46. Schvartsman G, Glitza IC, Milton D, Amaria R, Hwu P, Hwu WJ, Diab A, Wong MK, Patel SP, Wefel JS, Burton EM, Brown C, Woodman SE, Beosch IM, Chung C, Davies MA, Tawbi H. A phase II study of bevacizumab (BEV) in combination with atezolizumab (ATEZO) in pts (PTS) with untreated melanoma brain metastases (BEAT-MBM). ASCO Meeting Library. e-Pub 2018.
47. Tawbi H, Amaria A, Glitza IC, Milton D, Hwu WJ, Patel SP, Wong MK, Yee C, Woodman SE, McQuade J, Hwu P, Perdon K, Shephard M, Burton E, Wargo JA, Davies MA. Safety and preliminary activity data form a single center phase II study of triplet combination of nivolumab (N) with dabrafenib (D) and trametinib (T) [trident] in patients (Pts) with BRAF-mutated metastatic melanoma (MM). ASCO Meeting Library. e-Pub 2018.
48. Haymaker C, Uemura M, Murthy R, James M, Wang D, Brevard J, Swann S, Geib J, Cornfeld M, Chunduru S, Agrawal S, Yee C, Wargo J, Amaria R, Patel S, Tawbi H, Glitza IC, Woodman S, Hwu WJ, Davies M, Hwu P, Overwijk W, Bernatchez C, Diab A. Translational evidence of reactivated innate and adaptive immunity with intratumoral IMO-2125 in combination with systemic checkpoint inhibitors from a Phase I/II study in patients with anti-PD-1 refractory metastatic melanoma. AACR 2017. e-Pub 2017.
49. Vishnoi M, Liu H, Boral D, Yin W, Sprouse M, Thiery J, Glitza IC, Marchetti D. Translating CTCs for clinical use: melanoma patient-derived CTCs evolution in xenografts. AACR 2017. e-Pub 2017.
50. Glitza IC, Ma J, Ferguson S, Bassett R, Haydu L, Davies M. Characteristics of metastatic melanoma (MM) patients with leptomeningeal disease (LMD) and survival of > 1 year. ESMO 2017. e-Pub 2017.
51. Diab A, Haymaker C, Uemura M, Murthy R, James M, Geib J, Cornfeld M, Swann S, Yee C, Wargo J, Amaria R, Patel S, Tawbi H, Glitza IC, Woodman S, Hwu WJ, Davies M, Overwijk W, Bernatchez C, Hwu P. A phase 1/2 trial of intratumoral (i.t.) IMO-2125 (IMO) in combination with checkpoint inhibitors (CPI) in PD-(L)1- refractory melanoma. ESMO 2017. e-Pub 2017.
52. Haydu L, Gershenwald J, Glitza IC, Amaria R, Lazar A, Prieto V, Tawbi H, Tetzlaff M, Wargo J, Davies M. Refining risk models for distant and CNS metastasis in Stage III melanoma. SMR 2017. e-Pub 2017.
53. Andrews M, Chen W, Spencer C, Gopalakrishnan V, Tawbi H, Lazar A, Tetzlaff M, Patel S, Hwu P, Hwu WJ, Diab A, Glitza IC, Amaria R, Burton E, Woodman S, Davies M, Gershenwald J, Sharma P, Allison J, Futreal A, Wargo J. Molecular, immune and microbial predictors of response and toxicity to combination immune checkpoint blockade (CICB) in melanoma (MEL) patients. SMR 2017. e-Pub 2017.
54. Amaria R, Haymaker C, Forget M, Bernatchez C, Patel V, Carpio D, Patel S, Hwu WJ, Wong M, Davies M, Diab A, Glitza IC, Tawbi H, Hwu P. TGF-B Dominant Negative Receptor (TGF-DNRII) and NGFR-transduced tumor infiltrating lymphocytes (TIL) and high dose interleukin-2 (IL-2) in patients (pts) with metastatic melanoma (MM). SMR 2017. e-Pub 2017.
55. Johnson D, Zobniw C, Trinh V, Bassett R, Ma J, Anderson J, Davis J, Joseph J, Uemura M, Yee C, Amaria R, Patel S, Tawbi H, Glitza IC, Davies M, Wong M, Woodman S, Hwu P, Hwu WJ, Wang Y, Diab A. Infliximab associated with faster symptom resolution compared to corticosteroids alone for management of immune related enterocolitis. SITC 2017. e-Pub 2017.
56. Johnson D, Lecagoonporn S, Bernatchez C, Haymaker C, Bentebibel S, Uemura M, Yee C, Amaria R, Patel S, Tawbi H, Glitza IC, Davies M, Wong M, Hwu WJ, Hwu P, Overwijk W, Diab A. Phase I/II safety and efficacy study of image guided intratumoral CD40 agonistic monoclonal antibody APX005M in combination with systemic pembrolizumab in metastatic melanoma patients. SITC 2017. e-Pub 2017.
57. Haymaker C, Uemura M, Hwu WJ, Murthy R, James M, Bhatta A, Bentebibel S, Brevard J, Geib J, Lipford K, Cornfeld M, Chunduru S, Yee C, Woodman S, Amaria R, Patel S, Tawbi H, Glitza IC, Davies M, Overwijk W, Hwu P, Bernatchez C, Diab A. TLR9 agonist harnesses innate immunity to drive tumor-infiltrating T cell expansion in distant lesions in a phase 1/2 study of intratumoral IMO-2125+ipilimumab in anti-PD1 refractory melanoma patients. SITC 2017. e-Pub 2017.
58. Reddy S, Amaria R, Spencer C, Tetzlaff M, Reuben A, Andrews M, Wang L, Woodman S, Zhu H, Blando J, Vence L, Zhang S, Jiang H, Gopalakrishnan V, Hudgens C, Wani K, Tawbi H, Diab A, Glitza IC, Patel S, Hwu WJ, Wong M, Hwu P, Cormier J, Lucci A, Royal R, Lee J, Simpson L, Burton E, Gershenwald J, Ross M, Allison J, Sharma P, Davies M, Wargo J. Neoadjuvant nivolumab versus combination ipilumumab and nivolumab followed by adjuvant nivolumab in patients with resectable stage II and oligometastatic stage IV melanoma: preliminary findings. SITC 2017. e-Pub 2017.
59. Uemura M, Haymaker C, Murthy R, James M, Cornfeld M, Chunduru S, Agrawal S, Yee C, Wargo J, Amaria R, Patel S, Tawbi H, Glitza IC, Woodman S, Hwu WJ, Davies M, Hwu P, Overwijk W, Bernatchez C, Diab A. Intratumoral (i.t.) IMO-2125 (IMO), a TLR9 agonist, in combination with ipilimumab (ipi) in PD-(L)1 refractory melanoma (RM). ASCO 2017. e-Pub 2016.
60. Sprouse ML, Welte T, Boral D, Liu HN, Yin W, Vishnoi M, Goswami-Sewell D, Li L, Pei G, Jia P, Glitza IC, Marchetti D. PMN-MDSCs Enhance CTC Metastatic Properties through Reciprocal Interactions via ROS/Notch/Nodal Signaling. International Journal of Molecular Sciences. e-Pub 2019.

Book Chapters

1. Glitza IC, Alqusairi R. Immunotherapy for Melanoma. In: Advances in Experimental Medicine & Biology. 2nd Edition. Springer Nature, 2018.
2. Glitza IC, Heimberger Amy, Sulman Erik, Davies MA. Prognostic Factors for Survival in Melanoma Patients with Brain Metastases. In: Brain Metastases from Primary Tumors, 2016.
3. Glitza IC, Kim DW, Chae YK, Kim KB. Targeted Therapy in Melanoma. In: Cancer Genetics. Springer: New York, 2016.
4. Glitza IC, Varadhachary GR. Special Issues in Hematology and Oncology. In: Cancer Consult: Expertise for Clinical Practice. Wiley-Blackwell, 817-821, 2014.
5. Berger JR, Glitza IC. In: Clinical Neurovirology. Marcel Dekker, Inc, 2003.

Letters to the Editor

1. Glitza IC, Ferguson SD, Guha-Thakurta N. Rapid resolution of leptomeningeal disease with targeted therapy in a metastatic melanoma patient. J Neurooncol 133: 663-665, 2017.