Iwan Paolucci, Ph.D.
Department of Interventional Radiology, Division of Diagnostic Imaging
About Dr. Iwan Paolucci
Dr. Paolucci is an Assistant Professor in the Department of Interventional Radiology at The University of Texas MD Anderson Cancer Center in Houston, TX. His background is in Computer Science and Biomedical Engineering, and he holds a PhD in Biomedical Engineering. His main areas of research include artificial intelligence and stereotactic and robotic image-guidance for treatment of hepatobiliary malignancies with a strong focus on thermal ablation of primary and secondary malignant liver tumors. Additionally, he investigates artificial intelligence-based methods for outcome prediction and treatment recommendation.
Read More
Research Interests
Thermal ablation of liver tumors, Stereotactic and Robotic guidance, Artificial intelligence and advanced image processing-based planning, monitoring, and response assessment.
Honors & Awards
| 2018 | Master Award in recognition for the highest average score in the master study course, RMS |
Selected Publications
Peer-Reviewed Articles
- Lin YM, Fellman BM, Taiji R, Paolucci I, Silva JAM, Koay EJ, Avritscher R, Mahvash A, Holliday EB, Lee SS, Kaseb AO, Das P, Vauthey JN, Odisio BC. Salvage Locoregional Therapy Following Progression After Radiotherapy for Hepatocellular Carcinoma Is Associated with Improved Outcomes. J Gastrointest Surg. e-Pub 2023. PMID: 37268830.
- Lin YM, Paolucci I, O'Connor CS, Anderson BM, Rigaud B, Fellman BM, Jones KA, Brock KK, Odisio BC. Ablative Margins of Colorectal Liver Metastases Using Deformable CT Image Registration and Autosegmentation. Radiology 307(2):e221373, 2023. e-Pub 2023. PMID: 36719291.
- Paolucci I, Lin YM, Jones AK, Brock KK, Odisio BC. Use of Contrast Media During CT-guided Thermal Ablation of Colorectal Liver Metastasis for Procedure Planning is Associated with Improved Immediate Outcomes. Cardiovasc Intervent Radiol 46(3):327-336, 2023. e-Pub 2023. PMID: 36609863.
- Paolucci I, Lin YM, Kawaguchi Y, Maki H, Jones AK, Calandri M, Kopetz S, Newhook TE, Brock KK, Vauthey JN, Odisio BC. Targeted exome-based predictors of patterns of progression of colorectal liver metastasis after percutaneous thermal ablation. Br J Cancer 128(1):130-136, 2023. e-Pub 2022. PMID: 36319850.
- Lin YM, Paolucci I, Anderson BM, O'Connor CS, Rigaud B, Briones-Dimayuga M, Jones KA, Brock KK, Fellman BM, Odisio BC. Study Protocol COVER-ALL: Clinical Impact of a Volumetric Image Method for Confirming Tumour Coverage with Ablation on Patients with Malignant Liver Lesions. Cardiovasc Intervent Radiol 45(12):1860-1867, 2022. e-Pub 2022. PMID: 36058995.
- Paolucci I, Ruiter SJS, Freedman J, Candinas D, de Jong KP, Weber S, Tinguely P. Volumetric analyses of ablation dimensions in microwave ablation for colorectal liver metastases. Int J Hyperthermia 39(1):639-648, 2022. PMID: 35465802.
- Lin YM, Paolucci I, Brock KK, Odisio BC. Image-Guided Ablation for Colorectal Liver Metastasis: Principles, Current Evidence, and the Path Forward. Cancers (Basel) 13(16), 2021. e-Pub 2021. PMID: 34439081.
- Sandu RM, Paolucci I, Ruiter SJS, Sznitman R, de Jong KP, Freedman J, Weber S, Tinguely P. Volumetric Quantitative Ablation Margins for Assessment of Ablation Completeness in Thermal Ablation of Liver Tumors. Front Oncol 11:623098, 2021. e-Pub 2021. PMID: 33777768.
- Tinguely P, Paolucci I, Ruiter SJS, Weber S, de Jong KP, Candinas D, Freedman J, Engstrand J. Stereotactic and Robotic Minimally Invasive Thermal Ablation of Malignant Liver Tumors: A Systematic Review and Meta-Analysis. Front Oncol 11:713685, 2021. e-Pub 2021. PMID: 34631539.
- Ruiter SJS, Tinguely P, Paolucci I, Engstrand J, Candinas D, Weber S, de Haas RJ, de Jong KP, Freedman J. 3D Quantitative Ablation Margins for Prediction of Ablation Site Recurrence After Stereotactic Image-Guided Microwave Ablation of Colorectal Liver Metastases: A Multicenter Study. Front Oncol 11:757167, 2021. e-Pub 2021. PMID: 34868968.
- Prevost GA, Eigl B, Paolucci I, Rudolph T, Peterhans M, Weber S, Beldi G, Candinas D, Lachenmayer A. Efficiency, Accuracy and Clinical Applicability of a New Image-Guided Surgery System in 3D Laparoscopic Liver Surgery. J Gastrointest Surg 24(10):2251-2258, 2020. e-Pub 2019. PMID: 31621024.
- Paolucci I, Sandu RM, Sahli L, Prevost GA, Storni F, Candinas D, Weber S, Lachenmayer A. Ultrasound Based Planning and Navigation for Non-Anatomical Liver Resections - An Ex-Vivo Study. IEEE Open J Eng Med Biol 1:3-8, 2020. e-Pub 2020. PMID: 35402957.
- Paolucci I, Schwalbe M, Prevost GA, Lachenmayer A, Candinas D, Weber S, Tinguely P. Design and implementation of an electromagnetic ultrasound-based navigation technique for laparoscopic ablation of liver tumors. Surg Endosc 32(7):3410-3419, 2018. e-Pub 2018. PMID: 29435744.
- Schwalbe M, Williamson T, Paolucci I, Fuss T, Baumgartner I, Candinas D, Weber S, Tinguely P. A concept for electromagnetic navigated targeting of liver tumors using an angiographic approach. Minim Invasive Ther Allied Technol 27(1):51-59, 2018. e-Pub 2017. PMID: 29179633.
Manuals, Teaching Aids, Other Teaching Publications
- Paolucci I. Exercises with code and documentation for the 'Computer Assisted Surgery' course. Github, 2019.
Other Articles
- Bulatovic M, Tinguely P, Weber S, Paolucci I Thermal ablation of irregular tumor shapes using robotic needle guidance. Jahrestagung der Deutschen Gesellschaft für Computer- und Roboterassistierte Chirurgie 2021.
- Paolucci I, Hermann J, Sandu R, Candinas D, Tinguely P, Weber S Thermal ablation volumes with configurable shapes. Jahrestagung der Deutschen Gesellschaft für Computer- und Roboterassistierte Chirurgie 2019.
- Paolucci I, Sandu RM, Sahli L, Candinas D, Weber S, Lachenmayer A Ex-vivo evaluation of an ultrasound-based planning and navigation method for non-anatomical liver resections. Jahrestagung der Deutschen Gesellschaft für Computer- und Roboterassistierte Chirurgie 2019.
- Sandu RM, Paolucci I, Tinguely P, Candinas D, Freedman J, Weber S Quantitative volumetric assessment of percutaneous image-guided microwave ablations for colorectal liver metastases. Jahrestagung der Deutschen Gesellschaft für Computer- und Roboterassistierte Chirurgie 2019.
- Paolucci I, Eigl B, Garcia A, Serra E, Weber S, Gimenez ME Stereotactic image-guidance for percutaneous transgastric irreversible electroporation of pancreatic tumors – an animal case. Jahrestagung der Deutschen Gesellschaft für Computer- und Roboterassistierte Chirurgie 2019.
- Sahli L, Weber S, Paolucci I Liver surface reconstruction from navigated ultrasound during image-guided liver surgery. Jahrestagung der Deutschen Gesellschaft für Computer- und Roboterassistierte Chirurgie 2018.
- Hrabuska R, Sandu RM, Paolucci I, Weber S A Framework for The Quantitative Assessment of Image-guided Percutaneous Ablation of Hepatic Lesions. Jahrestagung der Deutschen Gesellschaft für Computer- und Roboterassistierte Chirurgie 2018.
- Paolucci I, Schwalbe M, Williamson T, Peterhans M, Candinas D, Weber S, Tinguely P Design and Implementation of a Navigation System for Laparoscopic Tumor Ablation based on Intraoperative US. Jahrestagung der Deutschen Gesellschaft für Computer- und Roboterassistierte Chirurgie 2016.
Abstracts
- Hong J, Snoddy E, Jones KA, O'Connor C, Lin YM, Paolucci I, Odisio BC, Brock KK. Evaluating the feasibility of using reduced scan length for non-contrast CT during image-guided liver ablations. Proceedings Volume 12463, Medical Imaging 2023: Physics of Medical Imaging. e-Pub 2023.
- Paolucci I, Lin YM, Jones AK, Brock KK, Odisio BC. Local vs. distant progression following thermal ablation of colorectal liver metastasis – what is worse?. CIRSE 2022 Book of Abstracts. e-Pub 2022.
- Lin YM, O'Connor C, Anderson B, Paolucci I, Felllman B, Jones AK, Brock KK, Odisio BC. Minimum ablation margin assessment of colorectal liver metastasis using a novel AIͲbased automatic segmentation and biomechanical deformable registration. CIRSE 2022 Book of Abstracts. e-Pub 2022.
- Paolucci I, Lin YM, Jones A, Calandri M, Kopetz S, Newhook T, Brock KK, Vauthey JN, Odisio BC. Targeted exomeͲbased predictors of progression patterns of patients with colorectal liver metastasis after percutaneous thermal ablation. CIRSE 2022 Book of Abstracts. e-Pub 2022.
- Odisio BC, Lin YM, Paolucci I, Sheth RA, Metwalli Z, O'Connor C, Briones Dimayuga M, Chun Y, Vauthey JN, Fellman B, Jones AK, Brock KK. Clinical impact of a volumetric image method for confirming tumour coverage with Ablation on patients with malignant Liver Lesions (COVERͲALL Trial). CIRSE 2022 Book of Abstracts. e-Pub 2022.
- Lin Y, Fellman B, Taiji R, Paolucci I, Koay E, Avritscher R, Mahvash A, Holliday E, Lee S, Kaseb A, Das P, Vauthey JN, Odisio BC. Salvage locoregional therapy following radiotherapy for hepatocellular carcinoma is associated with improved outcomes. CIRSE 2022 Book of Abstracts. e-Pub 2022.
- Paolucci I, Lin YM, Jones AK, Brock KK, Odisio BC. The added value of intra-procedural contrast-enhanced CT prior to thermal ablation of colorectal liver metastasis. Society of Interventional Radiology 2022, 2022.
- Bluatovic M, Tinguely P, Weber S, Paolucci I. Thermal ablation of irregular tumor shapes using robotic needle guidance. Jahrestagung der Deutschen Gesellschaft für Computer- und Roboterassistierte Chirurgie 2021, 2021. e-Pub 2021.
- Paolucci I, Hermann J, Sandu R, Candinas D, Tinguely P, Weber S. Robotically customizable thermal ablation volumes. IEEE Engineering in Medicine & Biology International Student Conference 2019, Magdeburg, Germany : book of proceedings, 2019.
- Sandu R, Paolucci I, Tinguely P, Feedman J, Weber S. Quantitative Volumetric Assessment of CT-guided Ablation Treatments for Colorectal Liver Metastases. IEEE Engineering in Medicine & Biology International Student Conference 2019, Magdeburg, Germany : book of proceedings. e-Pub 2019.
- Paolucci I, Schwalbe M, Prevost GA, Lachenmayer A, Candinas D, Weber S, Tinguely P. An intraoperative ultrasound based navigation method for laparoscopic ablation of liver tumors. Computer Assisted Radiology and Surgery Proceedings of the 32nd International Congress and Exhibition Berlin. e-Pub 2018.
- Paolucci I, Schwalbe M, Prevost GA, Lachenmayer A, Candinas D, Weber S, Tinguely P. Intraoperative ultrasound based navigation for laparoscopic ablation of liver tumors. British journal of surgery, Abstracts of the 105th Annual Congress of the Swiss Society of Surgery. e-Pub 2018.
- Paolucci I, Eigl B, Prevost GA, Lachenmayer A, Peterhans M, Candinas D, Weber S, Beldi G. First experiences with an augmented reality navi-gation system for laparoscopic liver surgery. Swiss Knife. e-Pub 2018.
- Paolucci I, Schwalbe M, Prevost GA, Lachenmayer A, Candinas D, Weber S, Tinguely P. 3D Ultrasound-based Evaluation of a Navigation Approach based on Electromagnetically Tracked 2D US. Jahrestagung der Deutschen Gesellschaft für Computer- und Roboterassistierte Chirurgie 2017. e-Pub 2017.
- Schwalbe M, Paolucci I, Haine A, Hendrik TK, Baumgartner I, Weber S, Kammer RF. Stereotactic MRI based image guidance for the treatment of vascular malformations – a pilot study. Jahrestagung der Deutschen Gesellschaft für Computer- und Roboterassistierte Chirurgie 2017. e-Pub 2017.
Book Chapters
- Paolucci I, Sandu R-M, Tinguely P, Fuchs C-K, Maurer M, Candinas D, Weber S, Lachenmayer A. Stereotactic image-guidance for ablation of malignant liver tumors. In: Liver Cancer. IntechOpen, 2019.
Patient Reviews
CV information above last modified October 24, 2024