Jason T Huse, M.D., Ph.D.

Peer-Reviewed Articles

1. De, A, Forero, SA, Pirani, AM, Morales, JE, De La Fuente-Granada, M, Sebastian, S, Huse, J, Ballester, L, Weinberg, J, Lang Jr, FF, Akdemir, KC, McCarty, J. Single cell spatial profiling of the matrisome identifies region-specific adhesion and signaling networks in glioblastoma. Communications Biology 9(1), 2026. e-Pub 2026. PMID: 41366031.
2. Pirhoushiaran, M, Walker-Charles, K, Yao, TH, Putluri, S, Patel, N, Wang, DH, Wang, I, Arjuna, S, Dono, A, Bueno, A, Nguyen, S, Balar, AP, Huse, J, Kundu, S, Esquenazi, Y, Patel, C, Prabhu, SS, Lang Jr, FF, Ballester, L. Exploring CSF microRNA signatures as diagnostic biomarkers in adult-type diffuse gliomas. Non-coding RNA Research 18:22-38, 2026. e-Pub 2026. PMID: 41624475.
3. Yang, J, Yang, H, Yuan, Y, Zhang, C, Fu, Z, Chen, YY, Xiong, Y, Chen, S, Ling, K, Liu, Y, Huse, J, Chen, B, Chan, TA, Qi, Z, Zhang, Z, Liu, XP, Wang, Y. Prickle4 Drives Microenvironmental Remodeling and Resistance to Parp Inhibition in IDH-Mutant Glioma. Advanced Science 13(3), 2026. e-Pub 2026. PMID: 41236163.
4. Kumar, S, Pelster, MS, Hasanov, M, Guerrieri, R, Hudgens, CW, Ledesma, D, Wang, F, Fischer, G, Simon, JM, Haydu, LE, Katlowitz, KV, Yennu Nanda, VG, McQuade, JL, Kwong, L, Huse, J, Lazar, A, Tetzlaff, M, Gershenwald, JE, Joon, A, Chen, K, Li, Z, Ram, P, Ferguson, SD, Davies, MA. Integrated analysis of molecular and clinical features associated with overall survival in melanoma patients with brain metastasis. Acta Neuropathologica Communications 13(1), 2025. e-Pub 2025. PMID: 40229864.
5. Guerrieri, R, Fischer, GM, Cortez, JR, Knighton, B, Ledesma, D, Hudgens, CW, Delcid, YF, Hu, Q, Onana, CY, Carapeto, F, Tezlaff, MT, Huse, J, Hwu, P, Burton, EM, Glitza, IC, Davies, MA, Ferguson, SD. Preclinical models of melanoma leptomeningeal disease to assess intrathecal checkpoint blockade. Scientific reports 15(1), 2025. e-Pub 2025. PMID: 41038921.
6. Yu, K, Basu, S, Baquer, G, Ahn, R, Gantchev, J, Jindal, S, Regan, MS, Abou-Mrad, Z, Prabhu, MC, Williams, MJ, D’Souza, AD, Malinowski, S, Hopland, K, Elhanati, Y, Stopka, SA, Stortchevoi, A, Couturier, C, He, Z, Sun, JJ, Chen, Y, Espejo, A, Chow, KH, Yerrum, S, Kao, PL, Kerrigan, BP, Norberg, L, Nielsen, D, Douville, C, Sharma, P, Giantini-Larsen, AM, Hu, J, Ayoub, G, Elharouni, D, Polk, MJ, Landivar, AM, Masud, N, Ling, AL, Triggs, D, Piranlioglu, R, Ball, A, Soni, H, Solomon, IH, Vasquez, KL, Vogelzang, J, Puduvalli, VK, Huse, J, Kim, YB, Goswami, S, Lang Jr, FF, Sharma, P. Investigative needle core biopsies support multimodal deep-data generation in glioblastoma. Nature communications 16(1), 2025. e-Pub 2025. PMID: 40295505.
7. Yeboa DN, Whitfield BT, Lin R, Ejezie CL, Swanson TA, Beckham TH, Wang C, De B, Perni S, Tom MC, Li J, McGovern SL, Harrison R, Majd NK, Puduvalli VK, Aaroe AE, Loghin M, O'Brien BJ, Patel AD, Patel CB, Wefel JS, Taslicay CA, Gule-Monroe M, Paulino AC, McAleer MF, Grosshans DR, Ghia AJ, Jiang W, Chung C, Maor M, Yang CH, Gubbiotti MA, Kamiya-Matsuoka C, Ballester LY, Weathers SP, Huse JT. Prospective phase II clinical trial of molecular glioblastoma (historical grade 2 and 3 IDH wildtype gliomas) preliminary novel exploratory analyses : Treatment intensification, margin reduction and epigenetic stratified outcomes with radiation therapy and chemotherapy. J Neurooncol 176(1):72, 2025. e-Pub 2025. PMID: 41191157.
8. Morad, G, Damania, A, Melendez, B, Singh, BB, Veguilla, FJ, Soto, RA, Hoballah, YM, Sahasrabhojane, P, Wong, M, Ahmed, M, Rico, R, Lewis, KN, Wani, K, Shamsutdinova, D, Lazcano Segura, RN, Ingram, D, Goethe, E, Day, A, Flores, I, McDaniel, L, Chelvanambi, M, Johnson, S, Dimitriou, F, Gupta, P, Oberai, S, Zal, MA, Doss, P, Jamal, MA, Hayase, E, Wathoo, C, Norberg, L, Jenkins, SL, Nass, S, Gumin, J, Long, L, Yang, J, Bradley, GR, Bekal, MP, Dono, A, Pichardo-Rojas, PS, Andrewes, S, Ballester, L, Losh, JS, Liang, J, Huo, L, Nielsen, D, Parker Kerrigan, BC, Brastianos, PK, Fowlkes, NW, Chang, C, Jenq, RR, Gomez-Manzano, C, Huse, J, Davies, MA, Lazar, A, Bhat, KP, Tandon, N, Esquenazi, Y, Peterson, CB, Puduvalli, VK, Lang Jr, FF, Johnston, CD, Bullman, S, Ajami, NJ, Ferguson, SD, Wargo, J. Microbial signals in primary and metastatic brain tumors. Nature medicine 31(11):3675-3688, 2025. e-Pub 2025. PMID: 41238915.
9. Ling, AL, Gantchev, J, Prabhu, MC, Basu, S, Ahn, R, Holdhoff, M, Masud, N, Ball, A, Nikas, O, Villa, GR, Regan, MS, Baquer, G, Ayoub, G, Whittaker, CA, Abou-Mrad, Z, Santos, A, Couturier, C, Elharouni, D, Vogelzang, J, Yu, K, Chen, H, He, Z, Jiang, W, Lucas, CG, Sax, HE, Lang Jr, FF, Puduvalli, VK, Tabar, V, Brennan, CW, Boire, A, Holdhoff, M, Bettegowda, C, Cima, M, Solomon, IH, Yuan, Y, Tak, PP, Sharma, P, White, F, Ligon, KL, Agar, NY, Espejo, A, Sun, JJ, Chen, Y, Jindal, S, Huse, J, Goswami, S, Akdemir, KC, Hu, J, Sharma, P, Buchold, G. Serial multiomics uncovers anti-glioblastoma responses not evident by routine clinical analyses. Science translational medicine 17(819), 2025. e-Pub 2025. PMID: 41061048.
10. Mondal J, Nylund P, Malgulwar PB, Johnson WE, Huse JT. Synaptic transmission promotes brain metastatic outgrowth in breast cancer. JCI Insight 10(19):1-4, 2025. e-Pub 2025. PMID: 40920591.
11. Beckham, TH, Cha, E, Rooney, MK, Tom, MC, Perni, S, McAleer, MF, Li, J, Kudchadker, RJ, Prajapati, S, Zlateva, Y, Kaya, D, Ene, CI, Ferguson, SD, Huse, J, Prabhu, SS, Weinberg, J. Cesium-131 collagen tile brachytherapy for salvage of recurrent intracranial metastases. Journal of neuro-oncology 175(1):165-174, 2025. e-Pub 2025. PMID: 40549120.
12. Liu, Y, Huse, J, Kannan, KS. Expression graph network framework for biomarker discovery. Briefings in bioinformatics 26(5), 2025. e-Pub 2025. PMID: 41139924.
13. Yeboa, DN, Li, J, Lin, R, Prabhu, SS, Beckham, TH, Woodhouse, KD, Swanson, T, Weinberg, J, Wang, X, Chi, X, Ejezie, CL, Suki, D, Wang, C, Ene, CI, McCutcheon, IE, McGovern, SL, McAleer, MF, Tom, MC, Ghia, AJ, Perni, S, Jiang, W, De, BS, Chung, C, Kim, BY, O'Brien, BJ, Huse, J, Wefel, JS, Court, LE, Tawbi, H, Janku, F, Guha-Thakurta, N, Debnam, JM, Johnson, JM, Taslicay, CA, Alvarez-Breckenridge, C, Raza, SM, Heimberger, AB, DeMonte, F, North, RY, Briere, TM, de Groot, JF, Sawaya, RE, Grosshans, DR, Lang Jr, FF, Rao, G, Ferguson, SD. Therapy, Safety, and Logistics of Preoperative vs Postoperative Stereotactic Radiation Therapy. JAMA Oncology 11(8):890-899, 2025. e-Pub 2025. PMID: 40531511.
14. De A, Forero SA, Pirani A, Morales JE, De La Fuente-Granada M, Sebastian S, Huse JT, Ballester LY, Weinberg JS, Lang FF, Akdemir KC, McCarty JH. Single Cell Spatial Profiling Identifies Region-Specific Extracellular Matrix Adhesion and Signaling Networks in Glioblastoma. bioRxiv, 2025. e-Pub 2025. PMID: 40496929.
15. Dharmaiah S, Malgulwar PB, Johnson WE, Chen BA, Sharin V, Whitfield BT, Alvarez C, Tadimeti V, Farooqi AS, Huse JT. G-quadruplex stabilizer CX-5461 effectively combines with radiotherapy to target alpha-thalassemia/mental retardation X-linked-deficient malignant glioma. Neuro Oncol 27(4):932-947, 2025. e-Pub 2025. PMID: 39570009.
16. Nomura M, Spitzer A, Johnson KC, Garofano L, Nehar-Belaid D, Galili Darnell N, Greenwald AC, Bussema L, Oh YT, Varn FS, D'Angelo F, Gritsch S, Anderson KJ, Migliozzi S, Gonzalez Castro LN, ChowdhFury T, Robine N, Reeves C, Park JB, Lipsa A, Hertel F, Golebiewska A, Niclou SP, Nusrat L, Kellet S, Das S, Moon HE, Paek SH, Bielle F, Laurenge A, Di Stefano AL, Mathon B, Picca A, Sanson M, Tanaka S, Saito N, Ashley DM, Keir ST, Ligon KL, Huse JT, Yung WKA, Lasorella A, Verhaak RGW, Iavarone A, Suva ML, Tirosh I. The multilayered transcriptional architecture of glioblastoma ecosystems. Nat Genet 57(5):1155-1167, 2025. e-Pub 2025. PMID: 40346361.
17. Spitzer A, Johnson KC, Nomura M, Garofano L, Nehar-Belaid D, Darnell NG, Greenwald AC, Bussema L, Oh YT, Varn FS, D'Angelo F, Gritsch S, Anderson KJ, Migliozzi S, Gonzalez Castro LN, Chowdhury T, Robine N, Reeves C, Park JB, Lipsa A, Hertel F, Golebiewska A, Niclou SP, Nusrat L, Kellet S, Das S, Moon HE, Paek SH, Bielle F, Laurenge A, Di Stefano AL, Mathon B, Picca A, Sanson M, Tanaka S, Saito N, Ashley DM, Keir ST, Ligon KL, Huse JT, Yung WKA, Lasorella A, Iavarone A, Verhaak RGW, Tirosh I, Suva ML. Deciphering the longitudinal trajectories of glioblastoma ecosystems by integrative single-cell genomics. Nat Genet 57(5):1168-1178, 2025. e-Pub 2025. PMID: 40346362.
18. Zhang, C, Chen, YY, Chen, S, Wang, Y, Yuan, Y, Yang, X, Hu, W, Chen, B, Qi, Z, Huse, J, Liu, Y, Wen, B, Liu, XP, Han, L, Wang, Y, Zhang, Z. Characterization of an Enhancer RNA Signature Reveals Treatment Strategies for Improving Immunotherapy Efficacy in Cancer. Cancer Research 85(8):1530-1543, 2025. e-Pub 2025. PMID: 39903841.
19. Mondal J, Zhang J, Qing F, Li S, Kumar D, Huse JT, Giancotti FG. Brd7 loss reawakens dormant metastasis initiating cells in lung by forging an immunosuppressive niche. Nat Commun 16(1):1378, 2025. e-Pub 2025. PMID: 39910049.
20. Liu, Y, Huse, J, Kannan, KS. A network-based discovery of prognostic markers in recurrent IDH wild-type gliomas. Frontiers in Genetics 16, 2025. e-Pub 2025.
21. Ene, CI, Abi Faraj, C, Beckham, TH, Weinberg, J, Andersen, C, Haider, A, Rao, G, Ferguson, SD, Alvarez-Brenkenridge, CA, Kim, BY, Heimberger, AB, McCutcheon, IE, Prabhu, SS, Wang, CM, Ghia, AJ, McGovern, SL, Chung, C, McAleer, MF, Tom, MC, Perni, S, Swanson, T, Yeboa, DN, Briere, TM, Huse, J, Fuller, GN, Lang Jr, FF, Li, J, Suki, D, Sawaya, RE. Response of treatment-naive brain metastases to stereotactic radiosurgery. Nature communications 15(1), 2024. e-Pub 2024. PMID: 38697991.
22. Wang, DH, Fujita, Y, Dono, A, Rodriguez-Armendariz, AG, Shah, M, Putluri, N, Pichardo-Rojas, PS, Patel, C, Zhu, JJ, Huse, J, Parker Kerrigan, BC, Lang Jr, FF, Esquenazi, Y, Ballester, L. The genomic alterations in glioblastoma influence the levels of CSF metabolites. Acta Neuropathologica Communications 12(1), 2024. e-Pub 2024. PMID: 38243318.
23. Gupta, P, Dang, M, Oberai, S, Migliozzi, S, Trivedi, R, Kumar, G, Peshoff, MM, Milam, N, Ahmed, A, Bojja, K, Tran, TM, Gumin, J, Kamiya Matsuoka, C, Huse, J, Cox, K, Li, J, Shehwana, H, Sheth, SA, Saxon, R, Baohua, S, Parker Kerrigan, BC, Maheshwari, A, Parra Cuentas, ER, Navin, N, Heimberger, AB, Lang Jr, FF, Iavarone, A, Dwyer, KC, Wang, L, Bhat, KP. Immune landscape of isocitrate dehydrogenase-stratified primary and recurrent human gliomas. Neuro-oncology 26(12):2239-2255, 2024. e-Pub 2024. PMID: 39126294.
24. Kumar, VA, Perez, A, Young, AL, Jones, J, O'Brien, BJ, Lang, FF, Huse, J, Fuller, GN. Collision tumor. Neuropathology 44(5):333-337, 2024. e-Pub 2024. PMID: 38414131.
25. Watson SS, Zomer A, Fournier N, Lourenco J, Quadroni M, Chryplewicz A, Nassiri S, Aubel P, Avanthay S, Croci D, Abels E, Broekman MLD, Hanahan D, Huse JT, Daniel RT, Hegi ME, Homicsko K, Cossu G, Hottinger AF, Joyce JA. Fibrotic response to anti-CSF-1R therapy potentiates glioblastoma recurrence. Cancer Cell 42(9):1507-1527.e11, 2024. e-Pub 2024. PMID: 39255775.
26. Peshoff, MM, Gupta, P, Oberai, S, Trivedi, R, Katayama, H, Chakrapani, P, Dang, M, Migliozzi, S, Gumin, J, Kadri, DB, Lin, JK, Milam, N, Maynard, ME, Vaillant, B, Parker Kerrigan, BC, Lang Jr, FF, Huse, J, Iavarone, A, Wang, L, Dwyer, KC, Bhat, KP. Triggering receptor expressed on myeloid cells 2 (TREM2) regulates phagocytosis in glioblastoma. Neuro-oncology 26(5):826-839, 2024. e-Pub 2024. PMID: 38237157.
27. Hariharan S, Whitfield BT, Pirozzi CJ, Waitkus MS, Brown MC, Bowie ML, Irvin DM, Roso K, Fuller R, Hostettler J, Dharmaiah S, Gibson EA, Briley A, Mangoli A, Fraley C, Shobande M, Stevenson K, Zhang G, Malgulwar PB, Roberts H, Roskoski M, Spasojevic I, Keir ST, He Y, Castro MG, Huse JT, Ashley DM. Interplay between ATRX and IDH1 mutations governs innate immune responses in diffuse gliomas. Nat Commun 15(1):730, 2024. e-Pub 2024. PMID: 38272925.
28. Malgulwar PB, Danussi C, Dharmaiah S, Johnson W, Singh A, Rai K, Rao A, Huse JT. Sirtuin 2 inhibition modulates chromatin landscapes genome-wide to induce senescence in ATRX-deficient malignant glioma. Neuro Oncol 26(1):55-67, 2024. e-Pub 2024. PMID: 37625115.
29. Odukoya, LA, Darko, K, Zerd, F, Ghomsi, NC, Kabare, G, Kamson, DO, Eckel-passow, JE, Guan, X, Kitange, GJ, Akinjo, AO, Badmos, KB, Bankole, O, Idowu, O, Karekezi, C, Edrick, E, Ekhator, C, Katasi, VM, Brown, DA, Huse, J, Llewellyn, H, Magambo, M, Magoha, M, Barrie, U, Ngaiza, A, Nyalundja, AD, Okemwa, M, Osei-Tutu, L, Petershie, B, Yevudza, WE, Anunobi, CC, Tiamiyu, L, Gankpe, GF, Heronima, K, Higgins, D, Schroeder, KM, Totimeh, T, Balogun, J, Cheserem, B, Etame, A, Fonkem, E. Establishment of a brain tumor consortium of Africa. Neuro-Oncology Advances 6(1), 2024. e-Pub 2024. PMID: 39659834.
30. Zhu, Y, Zhang, DY, Shukla, P, Jung, YH, Malgulwar, PB, Chagani, S, Colic, M, Benjamin, S, Copland, JA, Tan, L, Lorenzi, PL, Javle, M, Huse, J, Roszik, J, Hart, GT, Kwong, L. CRISPR screening identifies BET and mTOR inhibitor synergy in cholangiocarcinoma through serine glycine one carbon. JCI Insight 9(2), 2024. e-Pub 2024. PMID: 38060314.
31. Kan, P, Srinivasan, VM, Gumin, J, Garcia, R, Chen, SR, Johnson, J, Collins, DE, Chen, MM, Ledbetter, D, Huse, J, Luna, ZE, Robledo, A, Vasandani, V, Rao, A, Singh, S, Shpall, E, Fueyo-Margareto, J, Gomez-Manzano, C, Lang, FF. Development of a rabbit human glioblastoma model for testing of endovascular selective intra-arterial infusion (ESIA) of novel stem cell-based therapeutics. Neuro-oncology 26(1):127-136, 2024. e-Pub 2024. PMID: 37603323.
32. Nelson, BE, Reddy, NK, Huse, J, Amini, B, Nardo, M, Gouda, MA, Weathers, S, Subbiah, V. Histological transformation to gliosarcoma with combined BRAF/MEK inhibition in BRAF V600E mutated glioblastoma. npj Precision Oncology 7(1), 2023. e-Pub 2023. PMID: 37231247.
33. De, A, Lattier, JM, Morales, JE, Kelly, JR, Zheng, X, Chen, Z, Sebastian, S, Toosi, ZN, Huse, J, Lang Jr, FF, McCarty, J. Glial Cell Adhesion Molecule (GlialCAM) Determines Proliferative Versus Invasive Cell States in Glioblastoma. Journal of Neuroscience 43(47):8043-8057, 2023. e-Pub 2023. PMID: 37722850.
34. Shiau CK, Lu L, Kieser R, Fukumura K, Pan T, Lin HY, Yang J, Tong EL, Lee G, Yan Y, Huse JT, Gao R. High throughput single cell long-read sequencing analyses of same-cell genotypes and phenotypes in human tumors. Nat Commun 14(1):4124, 2023. e-Pub 2023. PMID: 37433798.
35. Hasanov M, Milton DR, Bea Davies A, Sirmans E, Saberian C, Posada EL, Opusunju S, Gershenwald JE, Torres-Cabala CA, Burton EM, Colen R, Huse JT, Glitza Oliva IC, Chung C, McAleer MF, McGovern SL, Yeboa DN, Kim BYS, Prabhu SS, McCutcheon IE, Weinberg J, Lang FF, Tawbi HA, Li J, Haydu LE, Davies MA, Ferguson SD. Changes In Outcomes And Factors Associated With Survival In Melanoma Patients With Brain Metastases. Neuro Oncol 25(7):1310-1320, 2023. e-Pub 2023. PMID: 36510640.
36. Walsh KM, Neff C, Bondy ML, Kruchko C, Huse JT, Amos CI, Barnholtz-Sloan JS, Ostrom QT. Influence of county-level geographic/ancestral origin on glioma incidence and outcomes in US Hispanics. Neuro Oncol 25(2):398-406, 2023. e-Pub 2023. PMID: 35868246.
37. Shiau CK, Lu L, Kieser R, Fukumura K, Pan T, Lin HY, Yang J, Tong EL, Lee G, Yan Y, Huse JT, Gao R. Delineating genotypes and phenotypes of individual cells from long-read single cell transcriptomes. bioRxiv, 2023. e-Pub 2023. PMID: 36778278.
38. Jahedi, A, Kumar, G, Kannan, L, Agarwal, T, Huse, J, Bhat, KP, Kannan, KS. Gibbs process distinguishes survival and reveals contact-inhibition genes in Glioblastoma multiforme. PloS one 18(2 February), 2023. e-Pub 2023. PMID: 36795646.
39. Malgulwar PB, Danussi C, Dharmaiah S, Johnson WE, Rao A, Huse JT. Sirtuin 2 inhibition modulates chromatin landscapes genome-wide to induce senescence in ATRX-deficient malignant glioma. bioRxiv, 2023. e-Pub 2023. PMID: 36711727.
40. Bhamidipati, D, Yedururi, S, Huse, J, Chinapuvvula, SV, Wu, J, Subbiah, V. Exceptional Responses to Selpercatinib in RET Fusion-Driven Metastatic Pancreatic Cancer. JCO Precision Oncology 7, 2023. e-Pub 2023. PMID: 38039431.
41. Ozkizilkaya HI, Johnson JM, O'Brien BJ, McCutcheon IE, Prabhu SS, Ghia AJ, Fuller GN, Huse JT, Ballester LY. Intracranial mesenchymal tumor, FET::CREB fusion-positive in the lateral ventricle. Neuro-Oncology Advances 5(1):vdad026, 2023. e-Pub 2023. PMID: 37051329.
42. Gregory, TA, Mastall, M, Lin, Y, Hess, KR, Yuan, Y, Martin-Bejarano Garcia, M, Fuller, GN, Alfaro, KD, Gule-Monroe, MK, Huse, J, Khatua, S, Rao, G, Sandberg, DI, Wefel, JS, Yeboa, DN, Paulino, AC, McGovern, SL, Zaky, W, Mahajan, A, Suki, D, Weathers, S, Harrison, R, De Groot, J, Puduvalli, VK, Penas-Prado, M, Majd, NK. Characterization of recurrence patterns and outcomes of medulloblastoma in adults. Neuro-Oncology Advances 5(1), 2023. e-Pub 2023. PMID: 37114244.
43. Huse JT. A Promising Preclinical Model For Tert Promoter Mutation In Glioblastoma. Neuro Oncol 24(12):2076-2077, 2022. e-Pub 2022. PMID: 35780432.
44. Danussi C, Bose P, Parthasarathy PT, Silberman PC, Van Arnam JS, Vitucci M, Tang OY, Heguy A, Wang Y, Chan TA, Riggins GJ, Sulman EP, Lang FF, Creighton CJ, Deneen B, Miller CR, Picketts DJ, Kannan K, Huse JT. Author Correction: Atrx inactivation drives disease-defining phenotypes in glioma cells of origin through global epigenomic remodeling. Nat Commun 13(1):190, 2022. e-Pub 2022. PMID: 34987156.
45. Gates, ED, Suki, D, Celaya, A, Weinberg, J, Prabhu, SS, Sawaya, RE, Huse, J, Long, JP, Fuentes, DA, Schellingerhout, D. Cellular Density in Adult Glioma, Estimated with MR Imaging Data and a Machine Learning Algorithm, Has Prognostic Power ApproachingWorld Health Organization Histologic Grading in a Cohort of 1181 Patients. American Journal of Neuroradiology 43(10):1411-1417, 2022. e-Pub 2022. PMID: 36109124.
46. Yang J, Wang Q, Zhang ZY, Long L, Ezhilarasan R, Karp JM, Tsirigos A, Snuderl M, Wiestler B, Wick W, Miao Y, Huse JT, Sulman EP. DNA methylation-based epigenetic signatures predict somatic genomic alterations in gliomas. Nat Commun 13(1):4410, 2022. e-Pub 2022. PMID: 35906213.
47. Varn FS, Johnson KC, Martinek J, Huse JT, Nasrallah MP, Wesseling P, Cooper LAD, Malta TM, Wade TE, Sabedot TS, Brat D, Gould PV, Woehrer A, Aldape K, Ismail A, Sivajothi SK, Barthel FP, Kim H, Kocakavuk E, Ahmed N, White K, Datta I, Moon HE, Pollock S, Goldfarb C, Lee GH, Garofano L, Anderson KJ, Nehar-Belaid D, Barnholtz-Sloan JS, Bakas S, Byrne AT, D'Angelo F, Gan HK, Khasraw M, Migliozzi S, Ormond DR, Paek SH, Van Meir EG, Walenkamp AME, Watts C, Weiss T, Weller M, Palucka K, Stead LF, Poisson LM, Noushmehr H, Iavarone A, Verhaak RGW. Glioma progression is shaped by genetic evolution and microenvironment interactions. Cell 185(12):2184-2199.e16, 2022. e-Pub 2022. PMID: 35649412.
48. Groot J, Ott M, Wei J, Kassab C, Fang D, Najem H, O'Brien B, Weathers SP, Matsouka CK, Majd NK, Harrison RA, Fuller GN, Huse JT, Long JP, Sawaya R, Rao G, MacDonald TJ, Priebe W, DeCuypere M, Heimberger AB. A first-in-human Phase I trial of the oral p-STAT3 inhibitor WP1066 in patients with recurrent malignant glioma. CNS Oncol 11(2):CNS87, 2022. e-Pub 2022. PMID: 35575067.
49. Najem H, Ott M, Kassab C, Rao A, Rao G, Marisetty A, Sonabend AM, Horbinski C, Verhaak R, Shankar A, Krishnan SN, Varn FS, Arrieta VA, Gupta P, Ferguson SD, Huse JT, Fuller GN, Long JP, Winkowski DE, Freiberg BA, James CD, Platanias LC, Lesniak MS, Burks JK, Heimberger AB. Central nervous system immune interactome is a function of cancer lineage, tumor microenvironment, and STAT3 expression. JCI Insight 7(9), 2022. e-Pub 2022. PMID: 35316217.
50. Qin T, Mullan B, Ravindran R, Messinger D, Siada R, Cummings JR, Harris M, Muruganand A, Pyaram K, Miklja Z, Reiber M, Garcia T, Tran D, Danussi C, Brosnan-Cashman J, Pratt D, Zhao X, Rehemtulla A, Sartor MA, Venneti S, Meeker AK, Huse JT, Morgan MA, Lowenstein PR, Castro MG, Yadav VN, Koschmann C. ATRX loss in glioma results in dysregulation of cell-cycle phase transition and ATM inhibitor radio-sensitization. Cell Rep 38(2):110216, 2022. e-Pub 2022. PMID: 35021084.
51. Fukumura K, Malgulwar PB, Fischer GM, Hu X, Mao X, Song X, Hernandez SD, Zhang XH, Zhang J, Parra ER, Yu D, Debeb BG, Davies MA, Huse JT. Multi-omic molecular profiling reveals potentially targetable abnormalities shared across multiple histologies of brain metastasis. Acta Neuropathol 141(2):303-321, 2021. e-Pub 2021. PMID: 33394124.
52. Lee WC, Reuben A, Hu X, McGranahan N, Chen R, Jalali A, Negrao MV, Hubert SM, Tang C, Wu CC, Lucas AS, Roh W, Suda K, Kim J, Tan AC, Peng DH, Lu W, Tang X, Chow CW, Fujimoto J, Behrens C, Kalhor N, Fukumura K, Coyle M, Thornton R, Gumbs C, Li J, Wu CJ, Little L, Roarty E, Song X, Lee JJ, Sulman EP, Rao G, Swisher S, Diao L, Wang J, Heymach JV, Huse JT, Scheet P, Wistuba II, Gibbons DL, Futreal PA, Zhang J, Gomez D, Zhang J. Multiomics profiling of primary lung cancers and distant metastases reveals immunosuppression as a common characteristic of tumor cells with metastatic plasticity. Genome Biol 21(1):271, 2020. e-Pub 2020. PMID: 33148332.
53. Chang G, Shi L, Ye Y, Shi H, Zeng L, Tiwary S, Huse JT, Huo L, Ma L, Ma Y, Zhang S, Zhu J, Xie V, Li P, Han L, He C, Huang S. YTHDF3 Induces the Translation of m6A-Enriched Gene Transcripts to Promote Breast Cancer Brain Metastasis. Cancer Cell. e-Pub 2020. PMID: 33125861.
54. Lattier JM, De A, Chen Z, Morales JE, Lang FF, Huse JT, McCarty JH. Megalencephalic leukoencephalopathy with subcortical cysts 1 (MLC1) promotes glioblastoma cell invasion in the brain microenvironment. Oncogene. e-Pub 2020. PMID: 33040087.
55. Ott M, Tomaszowski KH, Marisetty A, Kong LY, Wei J, Duna M, Blumberg K, Ji X, Jacobs C, Fuller GN, Langford LA, Huse JT, Long JP, Hu J, Li S, Weinberg JS, Prabhu SS, Sawaya R, Ferguson S, Rao G, Lang FF, Curran MA, Heimberger AB. Profiling of patients with glioma reveals the dominant immunosuppressive axis is refractory to immune function restoration. JCI Insight 5(17), 2020. e-Pub 2020. PMID: 32721947.
56. Akkari L, Bowman RL, Tessier J, Klemm F, Handgraaf SM, de Groot M, Quail DF, Tillard L, Gadiot J, Huse JT, Brandsma D, Westerga J, Watts C, Joyce JA. Dynamic changes in glioma macrophage populations after radiotherapy reveal CSF-1R inhibition as a strategy to overcome resistance. Sci Transl Med 12(552), 2020. e-Pub 2020. PMID: 32669424.
57. Barekatain Y, Yan VC, Arthur K, Ackroyd JJ, Khadka S, De Groot J, Huse JT, Muller FL. Robust detection of oncometabolic aberrations by 1H-13C heteronuclear single quantum correlation in intact biological specimens. Commun Biol 3(1):328, 2020. e-Pub 2020. PMID: 32587392.
58. Grkovski M, Kohutek ZA, Schöder H, Brennan CW, Tabar VS, Gutin PH, Zhang Z, Young RJ, Beattie BJ, Zanzonico PB, Huse JT, Rosenblum MK, Blasberg RG, Humm JL, Beal K. 18F-Fluorocholine PET uptake correlates with pathologic evidence of recurrent tumor after stereotactic radiosurgery for brain metastases. Eur J Nucl Med Mol Imaging 47(6):1446-1457, 2020. e-Pub 2020. PMID: 31865407.
59. Zhang L, Yao J, Wei Y, Zhou Z, Li P, Qu J, Badu-Nkansah A, Yuan X, Huang YW, Fukumura K, Mao X, Chang WC, Saunus J, Lakhani S, Huse JT, Hung MC, Yu D. Blocking immunosuppressive neutrophils deters pY696-EZH2-driven brain metastases. Sci Transl Med 12(545), 2020. e-Pub 2020. PMID: 32461334.
60. Wang Y, Wild AT, Turcan S, Wu WH, Sigel C, Klimstra DS, Ma X, Gong Y, Holland EC, Huse JT, Chan TA. Targeting therapeutic vulnerabilities with PARP inhibition and radiation in IDH-mutant gliomas and cholangiocarcinomas. Sci Adv 6(17):eaaz3221, 2020. e-Pub 2020. PMID: 32494639.
61. de Groot J, Penas-Prado M, Alfaro-Munoz K, Hunter K, Pei BL, O'Brien B, Weathers SP, Loghin M, Kamiya Matsouka C, Yung WKA, Mandel J, Wu J, Yuan Y, Zhou S, Fuller GN, Huse J, Rao G, Weinberg JS, Prabhu SS, McCutcheon IE, Lang FF, Ferguson SD, Sawaya R, Colen R, Yadav SS, Blando J, Vence L, Allison J, Sharma P, Heimberger AB. Window-of-opportunity clinical trial of pembrolizumab in patients with recurrent glioblastoma reveals predominance of immune-suppressive macrophages. Neuro Oncol 22(4):539-549, 2020. e-Pub 2020. PMID: 31755915.
62. Weathers SP, Penas-Prado M, Pei BL, Ling X, Kassab C, Banerjee P, Bdiwi M, Shaim H, Alsuliman A, Shanley M, de Groot JF, O'Brien BJ, Harrison R, Majd N, Kamiya-Matsuoka C, Fuller GN, Huse JT, Chi L, Rao G, Weinberg JS, Lang FF, Sawaya R, Shpall EJ, Rezvani K, Heimberger AB. Glioblastoma-mediated immune dysfunction limits CMV-specific T cells and therapeutic responses; results from a Phase I/II trial. Clin Cancer Res. e-Pub 2020. PMID: 32299815.
63. Ostrom QT, Egan KM, Nabors LB, Gerke T, Thompson RC, Olson JJ, LaRocca R, Chowdhary S, Eckel-Passow JE, Armstrong G, Wiencke JK, Bernstein JL, Claus EB, Il'yasova D, Johansen C, Lachance DH, Lai RK, Merrell RT, Olson SH, Sadetzki S, Schildkraut JM, Shete S, Houlston RS, Jenkins RB, Wrensch MR, Melin B, Amos CI, Huse JT, Barnholtz-Sloan JS, Bondy ML. Glioma risk associated with extent of estimated European genetic ancestry in African Americans and Hispanics. Int J Cancer 146(3):739-748, 2020. e-Pub 2020. PMID: 30963577.
64. Genomes Consortium IPAOW. Pan-cancer analysis of whole genomes. Nature 578(7793):82-93, 2020. e-Pub 2020. PMID: 32025007.
65. Barthel FP, Johnson KC, Varn FS, Moskalik AD, Tanner G, Kocakavuk E, Anderson KJ, Abiola O, Aldape K, Alfaro KD, Alpar D, Amin SB, Ashley DM, Bandopadhayay P, Barnholtz-Sloan JS, Beroukhim R, Bock C, Brastianos PK, Brat DJ, Brodbelt AR, Bruns AF, Bulsara KR, Chakrabarty A, Chakravarti A, Chuang JH, Claus EB, Cochran EJ, Connelly J, Costello JF, Finocchiaro G, Fletcher MN, French PJ, Gan HK, Gilbert MR, Gould PV, Grimmer MR, Iavarone A, Ismail A, Jenkinson MD, Khasraw M, Kim H, Kouwenhoven MCM, LaViolette PS, Li M, Lichter P, Ligon KL, Lowman AK, Malta TM, Mazor T, McDonald KL, Molinaro AM, Nam DH, Nayyar N, Ng HK, Ngan CY, Niclou SP, Niers JM, Noushmehr H, Noorbakhsh J, Ormond DR, Park CK, Poisson LM, Rabadan R, Radlwimmer B, Rao G, Reifenberger G, Sa JK, Schuster M, Shaw BL, Short SC, Smitt PAS, Sloan AE, Smits M, Suzuki H, Tabatabai G, Van Meir EG, Watts C, Weller M, Wesseling P, Westerman BA, Widhalm G, Woehrer A, Yung WKA, Zadeh G, Huse JT, De Groot JF, Stead LF, Verhaak RGW. Longitudinal molecular trajectories of diffuse glioma in adults. Nature 576(7785):112-120, 2019. e-Pub 2019. PMID: 31748746.
66. Juthani R, Madajewski B, Yoo B, Zhang L, Chen PM, Chen F, Turker MZ, Ma K, Overholtzer M, Longo VA, Carlin S, Aragon-Sanabria V, Huse JT, Gonen M, Zanzonico PB, Rudin CM, Wiesner U, Bradbury MS, Brennan CW. Ultrasmall Core-Shell Silica Nanoparticles for Precision Drug Delivery in a High-Grade Malignant Brain Tumor Model. Clin Cancer Res. e-Pub 2019. PMID: 31515460.
67. Kudo Y, Haymaker C, Zhang J, Reuben A, Duose DY, Fujimoto J, Roy-Chowdhuri S, Solis Soto LM, Dejima H, Parra ER, Mino B, Abraham R, Ikeda N, Vaporcyan A, Gibbons D, Zhang J, Lang FF, Luthra R, Lee JJ, Moran C, Huse JT, Kadara H, Wistuba II. Suppressed immune microenvironment and repertoire in brain metastases from patients with resected non-small-cell lung cancer. Ann Oncol 30(9):1521-1530, 2019. e-Pub 2019. PMID: 31282941.
68. Elshafeey N, Kotrotsou A, Hassan A, Elshafei N, Hassan I, Ahmed S, Abrol S, Agarwal A, El Salek K, Bergamaschi S, Acharya J, Moron FE, Law M, Fuller GN, Huse JT, Zinn PO, Colen RR. Multicenter study demonstrates radiomic features derived from magnetic resonance perfusion images identify pseudoprogression in glioblastoma. Nat Commun 10(1):3170, 2019. e-Pub 2019. PMID: 31320621.
69. Farooqi A, Yang J, Sharin V, Ezhilarasan R, Danussi C, Alvarez C, Dharmaiah S, Irvin D, Huse J, Sulman EP. Identification of patient-derived glioblastoma stem cell (GSC) lines with the alternative lengthening of telomeres phenotype. Acta Neuropathol Commun 7(1):76, 2019. e-Pub 2019. PMID: 31097032.
70. Fischer GM, Jalali A, Kircher DA, Lee WC, McQuade JL, Haydu LE, Joon AY, Reuben A, de Macedo MP, Carapeto FCL, Yang C, Srivastava A, Ambati CR, Sreekumar A, Hudgens CW, Knighton B, Deng W, Ferguson SD, Tawbi HA, Glitza IC, Gershenwald JE, Vashisht Gopal YN, Hwu P, Huse JT, Wargo JA, Futreal PA, Putluri N, Lazar AJ, DeBerardinis RJ, Marszalek JR, Zhang J, Holmen SL, Tetzlaff MT, Davies MA. Molecular Profiling Reveals Unique Immune and Metabolic Features of Melanoma Brain Metastases. Cancer Discov 9(5):628-645, 2019. e-Pub 2019. PMID: 30787016.
71. Ballester LY, Moghadamtousi SZ, Leeds NE, Huse JT, Fuller GN. Coexisting FGFR3 p.K650T mutation in two FGFR3-TACC3 fusion glioma cases. Acta Neuropathol Commun 7(1):63, 2019. e-Pub 2019. PMID: 31036092.
72. Hovinga KE, McCrea HJ, Brennan C, Huse J, Zheng J, Esquenazi Y, Panageas KS, Tabar V. EGFR amplification and classical subtype are associated with a poor response to bevacizumab in recurrent glioblastoma. J Neurooncol 142(2):337-345, 2019. e-Pub 2019. PMID: 30680510.
73. Mandel JJ, Youssef M, Nam J, Patel AJ, Jalali A, Ludmir EB, Liu D, Wu J, Armstrong G, Huse J, Bondy M, de Groot JF. Effect of health disparities on overall survival of patients with glioblastoma. J Neurooncol 142(2):365-374, 2019. e-Pub 2019. PMID: 30671709.
74. Wen PY, Touat M, Alexander BM, Mellinghoff IK, Ramkissoon S, McCluskey CS, Pelton K, Haidar S, Basu SS, Gaffey SC, Brown LE, Martinez-Ledesma JE, Wu S, Kim J, Wei W, Park MA, Huse JT, Kuhn JG, Rinne ML, Colman H, Agar NYR, Omuro AM, DeAngelis LM, Gilbert MR, de Groot JF, Cloughesy TF, Chi AS, Roberts TM, Zhao JJ, Lee EQ, Nayak L, Heath JR, Horky LL, Batchelor TT, Beroukhim R, Chang SM, Ligon AH, Dunn IF, Koul D, Young GS, Prados MD, Reardon DA, Yung WKA, Ligon KL. Buparlisib in Patients With Recurrent Glioblastoma Harboring Phosphatidylinositol 3-Kinase Pathway Activation: An Open-Label, Multicenter, Multi-Arm, Phase II Trial. J Clin Oncol 37(9):741-750, 2019. e-Pub 2019. PMID: 30715997.
75. Wang Y, Yang J, Wild AT, Wu WH, Shah R, Danussi C, Riggins GJ, Kannan K, Sulman EP, Chan TA, Huse JT. G-quadruplex DNA drives genomic instability and represents a targetable molecular abnormality in ATRX-deficient malignant glioma. Nat Commun 10(1):943, 2019. e-Pub 2019. PMID: 30808951.
76. Yeboa DN, Yu JB, Liao E, Huse J, Penas-Prado M, Kann BH, Sulman E, Grosshans D, Contessa J. Differences in patterns of care and outcomes between grade II and grade III molecularly defined 1p19q co-deleted gliomas. Clin Transl Radiat Oncol 15:46-52, 2019. e-Pub 2019. PMID: 30656222.
77. Majd NK, Metrus NR, Santos-Pinheiro F, Trevino CR, Fuller GN, Huse JT, Chung C, Ketonen L, Anderson MD, Penas-Prado M. RBM10 truncation in astroblastoma in a patient with history of mandibular ameloblastoma: A case report. Cancer Genet 231-232:41-45, 2019. e-Pub 2019. PMID: 30803556.
78. Wei J, Marisetty A, Schrand B, Gabrusiewicz K, Hashimoto Y, Ott M, Grami Z, Kong LY, Ling X, Caruso H, Zhou S, Wang YA, Fuller GN, Huse J, Gilboa E, Kang N, Huang X, Verhaak R, Li S, Heimberger AB. Osteopontin mediates glioblastoma-associated macrophage infiltration and is a potential therapeutic target. J Clin Invest 129(1):137-149, 2019. e-Pub 2019. PMID: 30307407.
79. Gates EDH, Yang J, Fukumura K, Lin JS, Weinberg JS, Prabhu SS, Long L, Fuentes D, Sulman EP, Huse JT, Schellingerhout D. Spatial Distance Correlates With Genetic Distance in Diffuse Glioma. Front Oncol 9:676, 2019. e-Pub 2019. PMID: 31417865.
80. Kaffes I, Szulzewsky F, Chen Z, Herting CJ, Gabanic B, Velázquez Vega JE, Shelton J, Switchenko JM, Ross JL, McSwain LF, Huse JT, Westermark B, Nelander S, Forsberg-Nilsson K, Uhrbom L, Maturi NP, Cimino PJ, Holland EC, Kettenmann H, Brennan CW, Brat DJ, Hambardzumyan D. Human Mesenchymal glioblastomas are characterized by an increased immune cell presence compared to Proneural and Classical tumors. Oncoimmunology 8(11):e1655360, 2019. e-Pub 2019. PMID: 31646100.
81. Jacobs DI, Fukumura K, Bainbridge MN, Armstrong GN, Tsavachidis S, Gu X, Doddapaneni HV, Hu J, Jayaseelan JC, Muzny DM, Huse JT, Bondy ML. Elucidating the molecular pathogenesis of glioma: integrated germline and somatic profiling of a familial glioma case series. Neuro Oncol 20(12):1625-1633, 2018. e-Pub 2018. PMID: 30165405.
82. Koehler JW, Miller AD, Miller CR, Porter B, Aldape K, Beck J, Brat D, Cornax I, Corps K, Frank C, Giannini C, Horbinski C, Huse JT, O'Sullivan MG, Rissi DR, Mark Simpson R, Woolard K, Shih JH, Mazcko C, Gilbert MR, LeBlanc AK. A Revised Diagnostic Classification of Canine Glioma: Towards Validation of the Canine Glioma Patient as a Naturally Occurring Preclinical Model for Human Glioma. J Neuropathol Exp Neurol 77(11):1039-1054, 2018. e-Pub 2018. PMID: 30239918.
83. Everson RG, Hashimoto Y, Freeman JL, Hodges TR, Huse J, Zhou S, Xiu J, Spetzler D, Sanai N, Kim L, Kesari S, Brenner A, De Monte F, Heimberger A, Raza SM. Multiplatform profiling of meningioma provides molecular insight and prioritization of drug targets for rational clinical trial design. J Neurooncol 139(2):469-478, 2018. e-Pub 2018. PMID: 29846894.
84. Ballester LY, Glitza Oliva IC, Douse DY, Chen MM, Lan C, Haydu LE, Huse JT, Roy-Chowdhuri S, Luthra R, Wistuba II, Davies MA. Evaluating Circulating Tumor DNA From the Cerebrospinal Fluid of Patients With Melanoma and Leptomeningeal Disease. J Neuropathol Exp Neurol 77(7):628-635, 2018. e-Pub 2018. PMID: 29873738.
85. Ferguson SD, Zhou S, Huse JT, de Groot JF, Xiu J, Subramaniam DS, Mehta S, Gatalica Z, Swensen J, Sanai N, Spetzler D, Heimberger AB. Targetable Gene Fusions Associate With the IDH Wild-Type Astrocytic Lineage in Adult Gliomas. J Neuropathol Exp Neurol 77(6):437-442, 2018. e-Pub 2018. PMID: 29718398.
86. Eterovic AK, Maher OM, Chandra J, Chen K, Huse J, Zaky W. Metachronous Medulloblastoma in a Child With Successfully Treated Neuroblastoma: Case Report and Novel Findings of DNA Sequencing. J Natl Compr Canc Netw 16(6):683-691, 2018. e-Pub 2018. PMID: 29891519.
87. Oldrini B, Á C, Marques C, Matia V, Ö U, Graña-Castro O, Torres-Ruiz R, Rodriguez-Perales S, Huse JT, Squatrito M. Somatic genome editing with the RCAS-TVA-CRISPR-Cas9 system for precision tumor modeling. Nat Commun 9(1):1466, 2018. e-Pub 2018. PMID: 29654229.
88. Ballester LY, Penas-Prado M, Leeds NE, Huse JT, Fuller GN. FGFR1 tyrosine kinase domain duplication in pilocytic astrocytoma with anaplasia. Cold Spring Harb Mol Case Stud 4(2), 2018. e-Pub 2018. PMID: 29610389.
89. Danussi C, Bose P, Parthasarathy PT, Silberman PC, Van Arnam JS, Vitucci M, Tang OY, Heguy A, Wang Y, Chan TA, Riggins GJ, Sulman EP, Lang FF, Creighton CJ, Deneen B, Miller CR, Picketts DJ, Kannan K, Huse JT. Atrx inactivation drives disease-defining phenotypes in glioma cells of origin through global epigenomic remodeling. Nat Commun 9(1):1057, 2018. e-Pub 2018. PMID: 29535300.
90. Turcan S, Makarov V, Taranda J, Wang Y, Fabius AWM, Wu W, Zheng Y, El-Amine N, Haddock S, Nanjangud G, LeKaye HC, Brennan C, Cross J, Huse JT, Kelleher NL, Osten P, Thompson CB, Chan TA. Mutant-IDH1-dependent chromatin state reprogramming, reversibility, and persistence. Nat Genet 50(1):62-72, 2018. e-Pub 2018. PMID: 29180699.
91. Gabrusiewicz K, Li X, Wei J, Hashimoto Y, Marisetty AL, Ott M, Wang F, Hawke D, Yu J, Healy LM, Hossain A, Akers JC, Maiti SN, Yamashita S, Shimizu Y, Dunner K, Zal MA, Burks JK, Gumin J, Nwajei F, Rezavanian A, Zhou S, Rao G, Sawaya R, Fuller GN, Huse JT, Antel JP, Li S, Cooper L, Sulman EP, Chen C, Geula C, Kalluri R, Zal T, Heimberger AB. Glioblastoma stem cell-derived exosomes induce M2 macrophages and PD-L1 expression on human monocytes. Oncoimmunology 7(4):e1412909, 2018. e-Pub 2018. PMID: 29632728.
92. Chakravarty D, Pedraza AM, Cotari J, Liu AH, Punko D, Kokroo A, Huse JT, Altan-Bonnet G, Brennan CW. EGFR and PDGFRA co-expression and heterodimerization in glioblastoma tumor sphere lines. Sci Rep 7(1):9043, 2017. e-Pub 2017. PMID: 28831081.
93. Yan D, Kowal J, Akkari L, Schuhmacher AJ, Huse JT, West BL, Joyce JA. Inhibition of colony stimulating factor-1 receptor abrogates microenvironment-mediated therapeutic resistance in gliomas. Oncogene. e-Pub 2017. PMID: 28759044.
94. Lee SH, Kim JS, Zheng S, Huse JT, Bae JS, Lee JW, Yoo KH, Koo HH, Kyung S, Park WY, Sung KW. ARID1B alterations identify aggressive tumors in neuroblastoma. Oncotarget 8(28):45943-45950, 2017. e-Pub 2017. PMID: 28521285.
95. Becher OJ, Gilheeney SW, Khakoo Y, Lyden DC, Haque S, De Braganca KC, Kolesar JM, Huse JT, Modak S, Wexler LH, Kramer K, Spasojevic I, Dunkel IJ. A phase I study of perifosine with temsirolimus for recurrent pediatric solid tumors. Pediatr Blood Cancer 64(7), 2017. e-Pub 2017. PMID: 28035748.
96. Grommes C, Pastore A, Palaskas N, Tang SS, Campos C, Schartz D, Codega P, Nichol D, Clark O, Hsieh WY, Rohle D, Rosenblum M, Viale A, Tabar VS, Brennan CW, Gavrilovic IT, Kaley TJ, Nolan CP, Omuro A, Pentsova E, Thomas AA, Tsyvkin E, Noy A, Palomba ML, Hamlin P, Sauter CS, Moskowitz CH, Wolfe J, Dogan A, Won M, Glass J, Peak S, Lallana EC, Hatzoglou V, Reiner AS, Gutin PH, Huse JT, Panageas KS, Graeber TG, Schultz N, DeAngelis LM, Mellinghoff IK. Ibrutinib Unmasks Critical Role of Bruton Tyrosine Kinase in Primary CNS Lymphoma. Cancer Discov. e-Pub 2017. PMID: 28619981.
97. Rajappa P, Cobb WS, Vartanian E, Huang Y, Daly L, Hoffman C, Zhang J, Shen B, Yanowitch R, Garg K, Cisse B, Haddock S, Huse J, Pisapia DJ, Chan TA, Lyden DC, Bromberg JF, Greenfield JP. Malignant Astrocytic Tumor Progression Potentiated by JAK-mediated Recruitment of Myeloid Cells. Clin Cancer Res 23(12):3109-3119, 2017. e-Pub 2017. PMID: 28039266.
98. Ballester LY, Huse JT, Tang G, Fuller GN. Molecular Classification of Adult Diffuse Gliomas: Conflicting IDH1/IDH2, ATRX and 1p/19q Results. Hum Pathol. e-Pub 2017. PMID: 28549927.
99. Thomas AA, Abrey LE, Terziev R, Raizer J, Martinez NL, Forsyth P, Paleologos N, Matasar M, Sauter CS, Moskowitz C, Nimer SD, DeAngelis LM, Kaley T, Grimm S, Louis DN, Cairncross JG, Panageas KS, Briggs S, Faivre G, Mohile NA, Mehta J, Jonsson P, Chakravarty D, Gao J, Schultz N, Brennan CW, Huse JT, Omuro A. Multicenter Phase II Study of Temozolomide and Myeloablative Chemotherapy with Autologous Stem Cell Transplant for Newly Diagnosed Anaplastic Oligodendroglioma. Neuro Oncol. e-Pub 2017. PMID: 28472509.
100. Huang Y, Rajappa P, Hu W, Hoffman C, Cisse B, Kim JH, Gorge E, Yanowitch R, Cope W, Vartanian E, Xu R, Zhang T, Pisapia D, Xiang J, Huse J, Matei I, Peinado H, Bromberg J, Holland E, Ding BS, Rafii S, Lyden D, Greenfield J. A proangiogenic signaling axis in myeloid cells promotes malignant progression of glioma. J Clin Invest 127(5):1826-1838, 2017. e-Pub 2017. PMID: 28394259.
101. Hodges TR, Ott M, Xiu J, Gatalica Z, Swensen J, Zhou S, Huse JT, de Groot J, Li S, Overwijk WW, Spetzler D, Heimberger AB. Mutational burden, immune checkpoint expression, and mismatch repair in glioma: implications for immune checkpoint immunotherapy. Neuro Oncol. e-Pub 2017. PMID: 28371827.
102. Lin X, Lee M, Buck O, Woo KM, Zhang Z, Hatzoglou V, Omuro A, Arevalo-Perez J, Thomas AA, Huse J, Peck K, Holodny AI, Young RJ. Diagnostic Accuracy of T1-Weighted Dynamic Contrast-Enhanced-MRI and DWI-ADC for Differentiation of Glioblastoma and Primary CNS Lymphoma. AJNR Am J Neuroradiol 38(3):485-491, 2017. e-Pub 2017. PMID: 27932505.
103. Huse JT, Snuderl M, Jones DT, Brathwaite CD, Altman N, Lavi E, Saffery R, Sexton-Oates A, Blumcke I, Capper D, Karajannis MA, Benayed R, Chavez L, Thomas C, Serrano J, Borsu L, Ladanyi M, Rosenblum MK. Polymorphous low-grade neuroepithelial tumor of the young (PLNTY): an epileptogenic neoplasm with oligodendroglioma-like components, aberrant CD34 expression, and genetic alterations involving the MAP kinase pathway. Acta Neuropathol 133(3):417-429, 2017. e-Pub 2017. PMID: 27812792.
104. Becher OJ, Millard NE, Modak S, Kushner BH, Haque S, Spasojevic I, Trippett TM, Gilheeney SW, Khakoo Y, Lyden DC, De Braganca KC, Kolesar JM, Huse JT, Kramer K, Cheung NV, Dunkel IJ. A phase I study of single-agent perifosine for recurrent or refractory pediatric CNS and solid tumors. PLoS One 12(6):e0178593, 2017. e-Pub 2017. PMID: 28582410.
105. Quail DF, Bowman RL, Akkari L, Quick ML, Schuhmacher AJ, Huse JT, Holland EC, Sutton JC, Joyce JA. The tumor microenvironment underlies acquired resistance to CSF-1R inhibition in gliomas. Science 352(6288):aad3018, 2016. e-Pub 2016. PMID: 27199435.
106. Roy DM, Walsh LA, Desrichard A, Huse JT, Wu W, Gao J, Bose P, Lee W, Chan TA. Integrated Genomics for Pinpointing Survival Loci within Arm-Level Somatic Copy Number Alterations. Cancer Cell 29(5):737-50, 2016. e-Pub 2016. PMID: 27165745.
107. Butowski N, Colman H, De Groot JF, Omuro AM, Nayak L, Wen PY, Cloughesy TF, Marimuthu A, Haidar S, Perry A, Huse J, Phillips J, West BL, Nolop KB, Hsu HH, Ligon KL, Molinaro AM, Prados M. Orally administered colony stimulating factor 1 receptor inhibitor PLX3397 in recurrent glioblastoma: an Ivy Foundation Early Phase Clinical Trials Consortium phase II study. Neuro Oncol 18(4):557-64, 2016. e-Pub 2016. PMID: 26449250.
108. Ceccarelli M, Barthel FP, Malta TM, Sabedot TS, Salama SR, Murray BA, Morozova O, Newton Y, Radenbaugh A, Pagnotta SM, Anjum S, Wang J, Manyam G, Zoppoli P, Ling S, Rao AA, Grifford M, Cherniack AD, Zhang H, Poisson L, Carlotti CG, Tirapelli DP, Rao A, Mikkelsen T, Lau CC, Yung WK, Rabadan R, Huse J, Brat DJ, Lehman NL, Barnholtz-Sloan JS, Zheng S, Hess K, Rao G, Meyerson M, Beroukhim R, Cooper L, Akbani R, Wrensch M, Haussler D, Aldape KD, Laird PW, Gutmann DH, Network TR, Noushmehr H, Iavarone A, Verhaak RG. Molecular Profiling Reveals Biologically Discrete Subsets and Pathways of Progression in Diffuse Glioma. Cell 164(3):550-63, 2016. e-Pub 2016. PMID: 26824661.
109. Oktay Y, Ülgen E, Ö C, Akyerli CB, Yüksel S, Erdemgil Y, Durasi IM, Henegariu OI, Nanni EP, Selevsek N, Grossmann J, Erson-Omay EZ, Bai H, Gupta M, Lee W, Turcan S, Özpinar A, Huse JT, Sav MA, Flanagan A, Günel M, Sezerman OU, Yakicier MC, Pamir MN, Özduman K. IDH-mutant glioma specific association of rs55705857 located at 8q24.21 involves MYC deregulation. Sci Rep 6:27569, 2016. e-Pub 2016. PMID: 27282637.
110. Lee EQ, Kaley TJ, Duda DG, Schiff D, Lassman AB, Wong ET, Mikkelsen T, Purow BW, Muzikansky A, Ancukiewicz M, Huse JT, Ramkissoon S, Drappatz J, Norden AD, Beroukhim R, Weiss SE, Alexander BM, McCluskey CS, Gerard M, Smith KH, Jain RK, Batchelor TT, Ligon KL, Wen PY. A Multicenter, Phase II, Randomized, Noncomparative Clinical Trial of Radiation and Temozolomide with or without Vandetanib in Newly Diagnosed Glioblastoma Patients. Clin Cancer Res 21(16):3610-8, 2015. e-Pub 2015. PMID: 25910950.
111. Heon EK, Wulan H, Macdonald LP, Malek AO, Braunstein GH, Eaves CG, Schattner MD, Allen PM, Alexander MO, Hawkins CA, McGovern DW, Freeman RL, Amir EP, Huse JD, Zaltzman JS, Kauff NP, Meyers PG, Gleason MH, Overholtzer MG, Wiseman SS, Streutker CD, Asa SW, McAlindon TP, Newcomb PO, Sorensen PM, Press OA. IL-15 induces strong but short-lived tumor-infiltrating CD8 T cell responses through the regulation of Tim-3 in breast cancer. Biochem Biophys Res Commun 464(1):360-6, 2015. e-Pub 2015. PMID: 26141233.
112. Moliterno J, Cope WP, Vartanian ED, Reiner AS, Kellen R, Ogilvie SQ, Huse JT, Gutin PH. Survival in patients treated for anaplastic meningioma. J Neurosurg 123(1):23-30, 2015. e-Pub 2015. PMID: 25859807.
113. Eckel-Passow JE, Lachance DH, Molinaro AM, Walsh KM, Decker PA, Sicotte H, Pekmezci M, Rice T, Kosel ML, Smirnov IV, Sarkar G, Caron AA, Kollmeyer TM, Praska CE, Chada AR, Halder C, Hansen HM, McCoy LS, Bracci PM, Marshall R, Zheng S, Reis GF, Pico AR, O'Neill BP, Buckner JC, Giannini C, Huse JT, Perry A, Tihan T, Berger MS, Chang SM, Prados MD, Wiemels J, Wiencke JK, Wrensch MR, Jenkins RB. Glioma Groups Based on 1p/19q, IDH, and TERT Promoter Mutations in Tumors. N Engl J Med 372(26):2499-508, 2015. e-Pub 2015. PMID: 26061753.
114. Research Network CGA, Brat DJ, Verhaak RG, Aldape KD, Yung WK, Salama SR, Cooper LA, Rheinbay E, Miller CR, Vitucci M, Morozova O, Robertson AG, Noushmehr H, Laird PW, Cherniack AD, Akbani R, Huse JT, Ciriello G, Poisson LM, Barnholtz-Sloan JS, Berger MS, Brennan C, Colen RR, Colman H, Flanders AE, Giannini C, Grifford M, Iavarone A, Jain R, Joseph I, Kim J, Kasaian K, Mikkelsen T, Murray BA, O'Neill BP, Pachter L, Parsons DW, Sougnez C, Sulman EP, Vandenberg SR, Van Meir EG, von Deimling A, Zhang H, Crain D, Lau K, Mallery D, Morris S, Paulauskis J, Penny R, Shelton T, Sherman M, Yena P, Black A, Bowen J, Dicostanzo K, Gastier-Foster J, Leraas KM, Lichtenberg TM, Pierson CR, Ramirez NC, Taylor C, Weaver S, Wise L, Zmuda E, Davidsen T, Demchok JA, Eley G, Ferguson ML, Hutter CM, Mills Shaw KR, Ozenberger BA, Sheth M, Sofia HJ, Tarnuzzer R, Wang Z, Yang L, Zenklusen JC, Ayala B, Baboud J, Chudamani S, Jensen MA, Liu J, Pihl T, Raman R, Wan Y, Wu Y, Ally A, Auman JT, Balasundaram M, Balu S, Baylin SB, Beroukhim R, Bootwalla MS, Bowlby R, Bristow CA, Brooks D, Butterfield Y, Carlsen R, Carter S, Chin L, Chu A, Chuah E, Cibulskis K, Clarke A, Coetzee SG, Dhalla N, Fennell T, Fisher S, Gabriel S, Getz G, Gibbs R, Guin R, Hadjipanayis A, Hayes DN, Hinoue T, Hoadley K, Holt RA, Hoyle AP, Jefferys SR, Jones S, Jones CD, Kucherlapati R, Lai PH, Lander E, Lee S, Lichtenstein L, Ma Y, Maglinte DT, Mahadeshwar HS, Marra MA, Mayo M, Meng S, Meyerson ML, Mieczkowski PA, Moore RA, Mose LE, Mungall AJ, Pantazi A, Parfenov M, Park PJ, Parker JS, Perou CM, Protopopov A, Ren X, Roach J, Sabedot TS, Schein J, Schumacher SE, Seidman JG, Seth S, Shen H, Simons JV, Sipahimalani P, Soloway MG, Song X, Sun H, Tabak B, Tam A, Tan D, Tang J, Thiessen N, Triche T, Van Den Berg DJ, Veluvolu U, Waring S, Weisenberger DJ, Wilkerson MD, Wong T, Wu J, Xi L, Xu AW, Yang L, Zack TI, Zhang J, Aksoy BA, Arachchi H, Benz C, Bernard B, Carlin D, Cho J, DiCara D, Frazer S, Fuller GN, Gao J. Comprehensive, Integrative Genomic Analysis of Diffuse Lower-Grade Gliomas. N Engl J Med 372(26):2481-98, 2015. e-Pub 2015. PMID: 26061751.
115. Kiess AP, Wolchok JD, Barker CA, Postow MA, Tabar V, Huse JT, Chan TA, Yamada Y, Beal K. Stereotactic radiosurgery for melanoma brain metastases in patients receiving ipilimumab: safety profile and efficacy of combined treatment. Int J Radiat Oncol Biol Phys 92(2):368-75, 2015. e-Pub 2015. PMID: 25754629.
116. Gupta A, Young RJ, Shah AD, Schweitzer AD, Graber JJ, Shi W, Zhang Z, Huse J, Omuro AM. Pretreatment Dynamic Susceptibility Contrast MRI Perfusion in Glioblastoma: Prediction of EGFR Gene Amplification. Clin Neuroradiol 25(2):143-50, 2015. e-Pub 2015. PMID: 24474262.
117. Hechtman JF, Sadowska J, Huse JT, Borsu L, Yaeger R, Shia J, Vakiani E, Ladanyi M, Arcila ME. AKT1 E17K in Colorectal Carcinoma Is Associated with BRAF V600E but Not MSI-H Status: A Clinicopathologic Comparison to PIK3CA Helical and Kinase Domain Mutants. Mol Cancer Res 13(6):1003-8, 2015. e-Pub 2015. PMID: 25714871.
118. Nayak L, Panageas KS, Reiner AS, Huse JT, Pentsova E, Braunthal SG, Abrey LE, DeAngelis LM, Lassman AB. Radiotherapy and temozolomide for anaplastic astrocytic gliomas. J Neurooncol 123(1):129-34, 2015. e-Pub 2015. PMID: 25920709.
119. Huse JT, Diamond EL, Wang L, Rosenblum MK. Mixed glioma with molecular features of composite oligodendroglioma and astrocytoma: a true "oligoastrocytoma"?. Acta Neuropathol 129(1):151-3, 2015. e-Pub 2015. PMID: 25359109.
120. Omuro A, Beal K, Gutin P, Karimi S, Correa DD, Kaley TJ, DeAngelis LM, Chan TA, Gavrilovic IT, Nolan C, Hormigo A, Lassman AB, Mellinghoff I, Grommes C, Reiner AS, Panageas KS, Baser RE, Tabar V, Pentsova E, Sanchez J, Barradas-Panchal R, Zhang J, Faivre G, Brennan CW, Abrey LE, Huse JT. Phase II study of bevacizumab, temozolomide, and hypofractionated stereotactic radiotherapy for newly diagnosed glioblastoma. Clin Cancer Res 20(19):5023-31, 2014. e-Pub 2014. PMID: 25107913.
121. Oricchio E, Papapetrou EP, Lafaille F, Ganat YM, Kriks S, Ortega-Molina A, Mark WH, Teruya-Feldstein J, Huse JT, Reuter V, Sadelain M, Studer L, Wendel HG. A cell engineering strategy to enhance the safety of stem cell therapies. Cell Rep 8(6):1677-85, 2014. e-Pub 2014. PMID: 25242333.
122. Gerber NK, Goenka A, Turcan S, Reyngold M, Makarov V, Kannan K, Beal K, Omuro A, Yamada Y, Gutin P, Brennan CW, Huse JT, Chan TA. Transcriptional diversity of long-term glioblastoma survivors. Neuro Oncol 16(9):1186-95, 2014. e-Pub 2014. PMID: 24662514.
123. Ozawa T, Riester M, Cheng YK, Huse JT, Squatrito M, Helmy K, Charles N, Michor F, Holland EC. Most human non-GCIMP glioblastoma subtypes evolve from a common proneural-like precursor glioma. Cancer Cell 26(2):288-300, 2014. e-Pub 2014. PMID: 25117714.
124. Ortiz B, Fabius AW, Wu WH, Pedraza A, Brennan CW, Schultz N, Pitter KL, Bromberg JF, Huse JT, Holland EC, Chan TA. Loss of the tyrosine phosphatase PTPRD leads to aberrant STAT3 activation and promotes gliomagenesis. Proc Natl Acad Sci U S A 111(22):8149-54, 2014. e-Pub 2014. PMID: 24843164.
125. Kastenhuber ER, Huse JT, Berman SH, Pedraza A, Zhang J, Suehara Y, Viale A, Cavatore M, Heguy A, Szerlip N, Ladanyi M, Brennan CW. Quantitative assessment of intragenic receptor tyrosine kinase deletions in primary glioblastomas: their prevalence and molecular correlates. Acta Neuropathol 127(5):747-59, 2014. e-Pub 2014. PMID: 24292886.
126. Cairncross JG, Wang M, Jenkins RB, Shaw EG, Giannini C, Brachman DG, Buckner JC, Fink KL, Souhami L, Laperriere NJ, Huse JT, Mehta MP, Curran WJ. Benefit from procarbazine, lomustine, and vincristine in oligodendroglial tumors is associated with mutation of IDH. J Clin Oncol 32(8):783-90, 2014. e-Pub 2014. PMID: 24516018.
127. Pietras A, Katz AM, Ekström EJ, Wee B, Halliday JJ, Pitter KL, Werbeck JL, Amankulor NM, Huse JT, Holland EC. Osteopontin-CD44 signaling in the glioma perivascular niche enhances cancer stem cell phenotypes and promotes aggressive tumor growth. Cell Stem Cell 14(3):357-69, 2014. e-Pub 2014. PMID: 24607407.
128. Hatzoglou V, Patel GV, Morris MJ, Curtis K, Zhang Z, Shi W, Huse J, Rosenblum M, Holodny AI, Young RJ. Brain metastases from prostate cancer: an 11-year analysis in the MRI era with emphasis on imaging characteristics, incidence, and prognosis. J Neuroimaging 24(2):161-6, 2014. e-Pub 2014. PMID: 23279641.
129. Valiente M, Obenauf AC, Jin X, Chen Q, Zhang XH, Lee DJ, Chaft JE, Kris MG, Huse JT, Brogi E, Massagué J. Serpins promote cancer cell survival and vascular co-option in brain metastasis. Cell 156(5):1002-16, 2014. e-Pub 2014. PMID: 24581498.
130. Huang Y, Hoffman C, Rajappa P, Kim JH, Hu W, Huse J, Tang Z, Li X, Weksler B, Bromberg J, Lyden DC, Greenfield JP. Oligodendrocyte progenitor cells promote neovascularization in glioma by disrupting the blood-brain barrier. Cancer Res 74(4):1011-21, 2014. e-Pub 2014. PMID: 24371228.
131. Young RJ, Gupta A, Shah AD, Graber JJ, Schweitzer AD, Prager A, Shi W, Zhang Z, Huse J, Omuro AM. Potential role of preoperative conventional MRI including diffusion measurements in assessing epidermal growth factor receptor gene amplification status in patients with glioblastoma. AJNR Am J Neuroradiol 34(12):2271-7, 2013. e-Pub 2013. PMID: 23811973.
132. Jacobsen A, Silber J, Harinath G, Huse JT, Schultz N, Sander C. Analysis of microRNA-target interactions across diverse cancer types. Nat Struct Mol Biol 20(11):1325-32, 2013. e-Pub 2013. PMID: 24096364.
133. Turcan S, Fabius AW, Borodovsky A, Pedraza A, Brennan C, Huse J, Viale A, Riggins GJ, Chan TA. Efficient induction of differentiation and growth inhibition in IDH1 mutant glioma cells by the DNMT Inhibitor Decitabine. Oncotarget 4(10):1729-36, 2013. e-Pub 2013. PMID: 24077826.
134. Pyonteck SM, Akkari L, Schuhmacher AJ, Bowman RL, Sevenich L, Quail DF, Olson OC, Quick ML, Huse JT, Teijeiro V, Setty M, Leslie CS, Oei Y, Pedraza A, Zhang J, Brennan CW, Sutton JC, Holland EC, Daniel D, Joyce JA. CSF-1R inhibition alters macrophage polarization and blocks glioma progression. Nat Med 19(10):1264-72, 2013. e-Pub 2013. PMID: 24056773.
135. Venneti S, Garimella MT, Sullivan LM, Martinez D, Huse JT, Heguy A, Santi M, Thompson CB, Judkins AR. Evaluation of histone 3 lysine 27 trimethylation (H3K27me3) and enhancer of Zest 2 (EZH2) in pediatric glial and glioneuronal tumors shows decreased H3K27me3 in H3F3A K27M mutant glioblastomas. Brain Pathol 23(5):558-64, 2013. e-Pub 2013. PMID: 23414300.
136. Huse JT, Edgar M, Halliday J, Mikolaenko I, Lavi E, Rosenblum MK. Multinodular and vacuolating neuronal tumors of the cerebrum: 10 cases of a distinctive seizure-associated lesion. Brain Pathol 23(5):515-24, 2013. e-Pub 2013. PMID: 23324039.
137. Ho AS, Kannan K, Roy DM, Morris LG, Ganly I, Katabi N, Ramaswami D, Walsh LA, Eng S, Huse JT, Zhang J, Dolgalev I, Huberman K, Heguy A, Viale A, Drobnjak M, Leversha MA, Rice CE, Singh B, Iyer NG, Leemans CR, Bloemena E, Ferris RL, Seethala RR, Gross BE, Liang Y, Sinha R, Peng L, Raphael BJ, Turcan S, Gong Y, Schultz N, Kim S, Chiosea S, Shah JP, Sander C, Lee W, Chan TA. The mutational landscape of adenoid cystic carcinoma. Nat Genet 45(7):791-8, 2013. e-Pub 2013. PMID: 23685749.
138. Venneti S, Felicella MM, Coyne T, Phillips JJ, Gorovets D, Huse JT, Kofler J, Lu C, Tihan T, Sullivan LM, Santi M, Judkins AR, Perry A, Thompson CB. Histone 3 lysine 9 trimethylation is differentially associated with isocitrate dehydrogenase mutations in oligodendrogliomas and high-grade astrocytomas. J Neuropathol Exp Neurol 72(4):298-306, 2013. e-Pub 2013. PMID: 23481705.
139. Omuro A, Chan TA, Abrey LE, Khasraw M, Reiner AS, Kaley TJ, Deangelis LM, Lassman AB, Nolan CP, Gavrilovic IT, Hormigo A, Salvant C, Heguy A, Kaufman A, Huse JT, Panageas KS, Hottinger AF, Mellinghoff I. Phase II trial of continuous low-dose temozolomide for patients with recurrent malignant glioma. Neuro Oncol 15(2):242-50, 2013. e-Pub 2013. PMID: 23243055.
140. Silber J, Hashizume R, Felix T, Hariono S, Yu M, Berger MS, Huse JT, VandenBerg SR, James CD, Hodgson JG, Gupta N. Expression of miR-124 inhibits growth of medulloblastoma cells. Neuro Oncol 15(1):83-90, 2013. e-Pub 2013. PMID: 23172372.
141. Fischer C, Haque SS, Huse JT, Blochin E, Souweidane MM, Lis E, Khakoo Y. Extraneural ependymoma: distant bone, lung, liver, and lymph node metastases following bevacizumab. Pediatr Blood Cancer 60(1):143-5, 2013. e-Pub 2013. PMID: 22976578.
142. Aldaz B, Sagardoy A, Nogueira L, Guruceaga E, Grande L, Huse JT, Aznar MA, Díez-Valle R, Tejada-Solís S, Alonso MM, Fernandez-Luna JL, Martinez-Climent JA, Malumbres R. Involvement of miRNAs in the differentiation of human glioblastoma multiforme stem-like cells. PLoS One 8(10):e77098, 2013. e-Pub 2013. PMID: 24155920.
143. Binda E, Visioli A, Giani F, Lamorte G, Copetti M, Pitter KL, Huse JT, Cajola L, Zanetti N, DiMeco F, De Filippis L, Mangiola A, Maira G, Anile C, De Bonis P, Reynolds BA, Pasquale EB, Vescovi AL. The EphA2 receptor drives self-renewal and tumorigenicity in stem-like tumor-propagating cells from human glioblastomas. Cancer Cell 22(6):765-80, 2012. e-Pub 2012. PMID: 23238013.
144. Bazzoli E, Pulvirenti T, Oberstadt MC, Perna F, Wee B, Schultz N, Huse JT, Fomchenko EI, Voza F, Tabar V, Brennan CW, DeAngelis LM, Nimer SD, Holland EC, Squatrito M. MEF promotes stemness in the pathogenesis of gliomas. Cell Stem Cell 11(6):836-44, 2012. e-Pub 2012. PMID: 23217424.
145. Kannan K, Inagaki A, Silber J, Gorovets D, Zhang J, Kastenhuber ER, Heguy A, Petrini JH, Chan TA, Huse JT. Whole-exome sequencing identifies ATRX mutation as a key molecular determinant in lower-grade glioma. Oncotarget 3(10):1194-203, 2012. e-Pub 2012. PMID: 23104868.
146. Gorovets D, Kannan K, Shen R, Kastenhuber ER, Islamdoust N, Campos C, Pentsova E, Heguy A, Jhanwar SC, Mellinghoff IK, Chan TA, Huse JT. IDH mutation and neuroglial developmental features define clinically distinct subclasses of lower grade diffuse astrocytic glioma. Clin Cancer Res 18(9):2490-501, 2012. e-Pub 2012. PMID: 22415316.
147. Szerlip NJ, Pedraza A, Chakravarty D, Azim M, McGuire J, Fang Y, Ozawa T, Holland EC, Huse JT, Jhanwar S, Leversha MA, Mikkelsen T, Brennan CW. Intratumoral heterogeneity of receptor tyrosine kinases EGFR and PDGFRA amplification in glioblastoma defines subpopulations with distinct growth factor response. Proc Natl Acad Sci U S A 109(8):3041-6, 2012. e-Pub 2012. PMID: 22323597.
148. Turcan S, Rohle D, Goenka A, Walsh LA, Fang F, Yilmaz E, Campos C, Fabius AW, Lu C, Ward PS, Thompson CB, Kaufman A, Guryanova O, Levine R, Heguy A, Viale A, Morris LG, Huse JT, Mellinghoff IK, Chan TA. IDH1 mutation is sufficient to establish the glioma hypermethylator phenotype. Nature 483(7390):479-83, 2012. e-Pub 2012. PMID: 22343889.
149. Silber J, Jacobsen A, Ozawa T, Harinath G, Pedraza A, Sander C, Holland EC, Huse JT. miR-34a repression in proneural malignant gliomas upregulates expression of its target PDGFRA and promotes tumorigenesis. PLoS One 7(3):e33844, 2012. e-Pub 2012. PMID: 22479456.
150. Shen R, Mo Q, Schultz N, Seshan VE, Olshen AB, Huse J, Ladanyi M, Sander C. Integrative subtype discovery in glioblastoma using iCluster. PLoS One 7(4):e35236, 2012. e-Pub 2012. PMID: 22539962.
151. Setty M, Helmy K, Khan AA, Silber J, Arvey A, Neezen F, Agius P, Huse JT, Holland EC, Leslie CS. Inferring transcriptional and microRNA-mediated regulatory programs in glioblastoma. Mol Syst Biol 8:605, 2012. e-Pub 2012. PMID: 22929615.
152. Pulvirenti T, Van Der Heijden M, Droms LA, Huse JT, Tabar V, Hall A. Dishevelled 2 signaling promotes self-renewal and tumorigenicity in human gliomas. Cancer Res 71(23):7280-90, 2011. e-Pub 2011. PMID: 21990322.
153. Morris LG, Taylor BS, Bivona TG, Gong Y, Eng S, Brennan CW, Kaufman A, Kastenhuber ER, Banuchi VE, Singh B, Heguy A, Viale A, Mellinghoff IK, Huse J, Ganly I, Chan TA. Genomic dissection of the epidermal growth factor receptor (EGFR)/PI3K pathway reveals frequent deletion of the EGFR phosphatase PTPRS in head and neck cancers. Proc Natl Acad Sci U S A 108(47):19024-9, 2011. e-Pub 2011. PMID: 22065749.
154. Litkowski P, Khakoo Y, Gilheeney S, Souweidane M, Huse J, Haque S, Young RJ. Hemangioma of the cavernous sinus in a child. Neurology 77(17):1647-8, 2011. e-Pub 2011. PMID: 22025460.
155. Huse JT, Nafa K, Shukla N, Kastenhuber ER, Lavi E, Hedvat CV, Ladanyi M, Rosenblum MK. High frequency of IDH-1 mutation links glioneuronal tumors with neuropil-like islands to diffuse astrocytomas. Acta Neuropathol 122(3):367-9, 2011. e-Pub 2011. PMID: 21755347.
156. Palaskas N, Larson SM, Schultz N, Komisopoulou E, Wong J, Rohle D, Campos C, Yannuzzi N, Osborne JR, Linkov I, Kastenhuber ER, Taschereau R, Plaisier SB, Tran C, Heguy A, Wu H, Sander C, Phelps ME, Brennan C, Port E, Huse JT, Graeber TG, Mellinghoff IK. 18F-fluorodeoxy-glucose positron emission tomography marks MYC-overexpressing human basal-like breast cancers. Cancer Res 71(15):5164-74, 2011. e-Pub 2011. PMID: 21646475.
157. Fomchenko EI, Dougherty JD, Helmy KY, Katz AM, Pietras A, Brennan C, Huse JT, Milosevic A, Holland EC. Recruited cells can become transformed and overtake PDGF-induced murine gliomas in vivo during tumor progression. PLoS One 6(7):e20605, 2011. e-Pub 2011. PMID: 21754979.
158. Squatrito M, Brennan CW, Helmy K, Huse JT, Petrini JH, Holland EC. Loss of ATM/Chk2/p53 pathway components accelerates tumor development and contributes to radiation resistance in gliomas. Cancer Cell 18(6):619-29, 2010. e-Pub 2010. PMID: 21156285.
159. Ozawa T, Brennan CW, Wang L, Squatrito M, Sasayama T, Nakada M, Huse JT, Pedraza A, Utsuki S, Yasui Y, Tandon A, Fomchenko EI, Oka H, Levine RL, Fujii K, Ladanyi M, Holland EC. PDGFRA gene rearrangements are frequent genetic events in PDGFRA-amplified glioblastomas. Genes Dev 24(19):2205-18, 2010. e-Pub 2010. PMID: 20889717.
160. Ney DE, Huse JT, Dunkel IJ, Steinherz PG, Haque S, Khakoo Y. Intraventricular meningioma after cranial irradiation for childhood leukemia. J Child Neurol 25(10):1292-5, 2010. e-Pub 2010. PMID: 20207611.
161. Becher OJ, Hambardzumyan D, Walker TR, Helmy K, Nazarian J, Albrecht S, Hiner RL, Gall S, Huse JT, Jabado N, MacDonald TJ, Holland EC. Preclinical evaluation of radiation and perifosine in a genetically and histologically accurate model of brainstem glioma. Cancer Res 70(6):2548-57, 2010. e-Pub 2010. PMID: 20197468.
162. Huse JT, Brennan C, Hambardzumyan D, Wee B, Pena J, Rouhanifard SH, Sohn-Lee C, le Sage C, Agami R, Tuschl T, Holland EC. The PTEN-regulating microRNA miR-26a is amplified in high-grade glioma and facilitates gliomagenesis in vivo. Genes Dev 23(11):1327-37, 2009. e-Pub 2009. PMID: 19487573.
163. Bleau AM, Hambardzumyan D, Ozawa T, Fomchenko EI, Huse JT, Brennan CW, Holland EC. PTEN/PI3K/Akt pathway regulates the side population phenotype and ABCG2 activity in glioma tumor stem-like cells. Cell Stem Cell 4(3):226-35, 2009. e-Pub 2009. PMID: 19265662.
164. Gasparetto EL, Pawlak MA, Patel SH, Huse J, Woo JH, Krejza J, Rosenfeld MR, O'Rourke DM, Lustig R, Melhem ER, Wolf RL. Posttreatment recurrence of malignant brain neoplasm: accuracy of relative cerebral blood volume fraction in discriminating low from high malignant histologic volume fraction. Radiology 250(3):887-96, 2009. e-Pub 2009. PMID: 19244052.
165. Perry A, Miller CR, Gujrati M, Scheithauer BW, Zambrano SC, Jost SC, Raghavan R, Qian J, Cochran EJ, Huse JT, Holland EC, Burger PC, Rosenblum MK. Malignant gliomas with primitive neuroectodermal tumor-like components: a clinicopathologic and genetic study of 53 cases. Brain Pathol 19(1):81-90, 2009. e-Pub 2009. PMID: 18452568.
166. Whitmore RG, Krejza J, Kapoor GS, Huse J, Woo JH, Bloom S, Lopinto J, Wolf RL, Judy K, Rosenfeld MR, Biegel JA, Melhem ER, O'Rourke DM. Prediction of oligodendroglial tumor subtype and grade using perfusion weighted magnetic resonance imaging. J Neurosurg 107(3):600-9, 2007. e-Pub 2007. PMID: 17886561.
167. Huse JT, Pasha TL, Zhang PJ. D2-40 functions as an effective chondroid marker distinguishing true chondroid tumors from chordoma. Acta Neuropathol 113(1):87-94, 2007. e-Pub 2007. PMID: 17021752.
168. Schessl J, Medne L, Hu Y, Zou Y, Brown MJ, Huse JT, Torigian DA, Jungbluth H, Goebel HH, Bönnemann CG. MRI in DNM2-related centronuclear myopathy: evidence for highly selective muscle involvement. Neuromuscul Disord 17(1):28-32, 2007. e-Pub 2007. PMID: 17134899.
169. Chen HI, Burnett MG, Huse JT, Lustig RA, Bagley LJ, Zager EL. Recurrent late cerebral necrosis with aggressive characteristics after radiosurgical treatment of an arteriovenous malformation. Case report. J Neurosurg 105(3):455-60, 2006. e-Pub 2006. PMID: 16961142.
170. Elmariah SB, Huse J, Mason B, Leroux P, Lustig RA. Multicentric glioblastoma multiforme in a patient with BRCA-1 invasive breast cancer. Breast J 12(5):470-4, 2006. e-Pub 2006. PMID: 16958968.
171. Cardillo S, Huse JT, Iqbal N. Diabetic muscle infarction of the forearm in a patient with long-standing type 1 diabetes. Endocr Pract 12(2):188-92, 2006. e-Pub 2006. PMID: 16690469.
172. Huse JT, Byant D, Yang Y, Pijak DS, D'Souza I, Lah JJ, Lee VM, Doms RW, Cook DG. Endoproteolysis of beta-secretase (beta-site amyloid precursor protein-cleaving enzyme) within its catalytic domain. A potential mechanism for regulation. J Biol Chem 278(19):17141-9, 2003. e-Pub 2003. PMID: 12551920.
173. Huse JT, Liu K, Pijak DS, Carlin D, Lee VM, Doms RW. Beta-secretase processing in the trans-Golgi network preferentially generates truncated amyloid species that accumulate in Alzheimer's disease brain. J Biol Chem 277(18):16278-84, 2002. e-Pub 2002. PMID: 11847218.
174. Huse JT, Pijak DS, Leslie GJ, Lee VM, Doms RW. Maturation and endosomal targeting of beta-site amyloid precursor protein-cleaving enzyme. The Alzheimer's disease beta-secretase. J Biol Chem 275(43):33729-37, 2000. e-Pub 2000. PMID: 10924510.

Invited Articles

1. de Blank P, Fouladi M, Huse JT. Molecular markers and targeted therapy in pediatric low-grade glioma. J Neurooncol. e-Pub 2020. PMID: 32399739.
2. Horbinski C, Ligon KL, Brastianos P, Huse JT, Venere M, Chang S, Buckner J, Cloughesy T, Jenkins RB, Giannini C, Stupp R, Nabors LB, Wen PY, Aldape KJ, Lukas RV, Galanis E, Eberhart CG, Brat DJ, Sarkaria JN. The medical necessity of advanced molecular testing in the diagnosis and treatment of brain tumor patients. Neuro Oncol 21(12):1498-1508, 2019. e-Pub 2019. PMID: 31276167.
3. Ostrom Q, Bondy ML, Huse JT. Integrating germline and somatic genomic analysis to probe etiological mechanism in malignant glioma. Oncotarget 10(33):3086-3087, 2019. e-Pub 2019. PMID: 31139320.
4. Danussi C, Huse JT. Novel insights into the epigenetics of diffuse glioma. Mol Cell Oncol 5(5):e1472055, 2018. e-Pub 2018. PMID: 30263940.
5. Wen PY, Huse JT. 2016 World Health Organization Classification of Central Nervous System Tumors. Continuum (Minneap Minn) 23(6, Neuro-oncology):1531-1547, 2017. e-Pub 2017. PMID: 29200109.
6. Huse JT. Establishing a Robust Molecular Taxonomy for Diffuse Gliomas of Adulthood. Surg Pathol Clin 9(3):379-90, 2016. e-Pub 2016. PMID: 27523967.
7. Huse JT, Rosenblum MK. The Emerging Molecular Foundations of Pediatric Brain Tumors. J Child Neurol 30(13):1838-50, 2015. e-Pub 2015. PMID: 25873586.
8. Venneti S, Huse JT. The evolving molecular genetics of low-grade glioma. Adv Anat Pathol 22(2):94-101, 2015. e-Pub 2015. PMID: 25664944.
9. Alexander BM, Galanis E, Yung WK, Ballman KV, Boyett JM, Cloughesy TF, Degroot JF, Huse JT, Mann B, Mason W, Mellinghoff IK, Mikkelsen T, Mischel PS, O'Neill BP, Prados MD, Sarkaria JN, Tawab-Amiri A, Trippa L, Ye X, Ligon KL, Berry DA, Wen PY. Brain Malignancy Steering Committee clinical trials planning workshop: report from the Targeted Therapies Working Group. Neuro Oncol 17(2):180-8, 2015. e-Pub 2015. PMID: 25165194.
10. Huse JT, Aldape KD. The evolving role of molecular markers in the diagnosis and management of diffuse glioma. Clin Cancer Res 20(22):5601-11, 2014. e-Pub 2014. PMID: 25398843.
11. Huse JT, Wallace M, Aldape KD, Berger MS, Bettegowda C, Brat DJ, Cahill DP, Cloughesy T, Haas-Kogan DA, Marra M, Miller CR, Nelson SJ, Salama SR, Soffietti R, Wen PY, Yip S, Yen K, Costello JF, Chang S. Where are we now? And where are we going? A report from the Accelerate Brain Cancer Cure (ABC2) low-grade glioma research workshop. Neuro Oncol 16(2):173-8, 2014. e-Pub 2014. PMID: 24305708.
12. Huse JT, Aldape KD. The molecular landscape of diffuse glioma and prospects for biomarker development. Expert Opin Med Diagn 7(6):573-87, 2013. e-Pub 2013. PMID: 24161073.
13. Kim JH, Huse JT, Huang Y, Lyden D, Greenfield JP. Molecular diagnostics in paediatric glial tumours. Lancet Oncol 14(1):e19-27, 2013. e-Pub 2013. PMID: 23276367.
14. Huse JT, Holland E, DeAngelis LM. Glioblastoma: molecular analysis and clinical implications. Annu Rev Med 64:59-70, 2013. e-Pub 2013. PMID: 23043492.
15. Huse JT, Phillips HS, Brennan CW. Molecular subclassification of diffuse gliomas: seeing order in the chaos. Glia 59(8):1190-9, 2011. e-Pub 2011. PMID: 21446051.
16. Huse JT, Holland EC. Targeting brain cancer: advances in the molecular pathology of malignant glioma and medulloblastoma. Nat Rev Cancer 10(5):319-31, 2010. e-Pub 2010. PMID: 20414201.
17. Huse JT, Holland EC. Yin and yang: cancer-implicated miRNAs that have it both ways. Cell Cycle 8(22):3611-2, 2009. e-Pub 2009. PMID: 19855181.
18. Bleau AM, Huse JT, Holland EC. The ABCG2 resistance network of glioblastoma. Cell Cycle 8(18):2936-44, 2009. e-Pub 2009. PMID: 19713741.
19. Huse JT, Holland EC. Genetically engineered mouse models of brain cancer and the promise of preclinical testing. Brain Pathol 19(1):132-43, 2009. e-Pub 2009. PMID: 19076778.
20. Huse JT, Doms RW. Neurotoxic traffic: uncovering the mechanics of amyloid production in Alzheimer's disease. Traffic 2(2):75-81, 2001. e-Pub 2001. PMID: 11247305.
21. Huse JT, Doms RW. Closing in on the amyloid cascade: recent insights into the cell biology of Alzheimer's disease. Mol Neurobiol 22(1-3):81-98, 2000. e-Pub 2000. PMID: 11414282.

Review Articles

1. Mondal, J, Huse, J. Neurotransmitter power plays. Acta Neuropathologica Communications 13(1), 2025. e-Pub 2025. PMID: 40307951.
2. Van Den Bent, MJ, Vogelbaum, MA, Cloughesy, TF, Galldiks, N, Albert, NL, Tonn, JC, Avila, EK, Fangusaro, J, Mirsky, DM, Sahgal, A, Soffietti, R, Karschnia, P, Mehta, MP, Kim, MM, Boele, F, Huse, J, Nayak, L, Lim-Fat, MJ, Le Rhun, E, Desjardins, A, Lee, EQ, Chukwueke, U, Koekkoek, JA, Mendoza, TR, Loughan, A, Budhu, JA, Bakas, S, Huang, R, Villanueva-Meyer, JE, Leone, JP, Okada, H, Reardon, DA, Bi, WL, Wen, PY, Chang, SM. Response Assessment in Neuro-Oncology (RANO) 2009–2025. Neuro-oncology 27(9):2209-2224, 2025. e-Pub 2025. PMID: 40317212.
3. Horbinski, C, Solomon, DA, Lukas, RV, Packer, RJ, Brastianos, PK, Wen, PY, Snuderl, M, Berger, M, Chang, SM, Fouladi, M, Phillips, JJ, Burt Nabors, L, Brat, DJ, Huse, J, Aldape, KD, Sarkaria, JN, Holdhoff, M, Burns, TC, Peters, KB, Mellinghoff, IK, Arons, DF, Galanis, E. Molecular Testing for the World Health Organization Classification of Central Nervous System Tumors. JAMA Oncology 11(3):317-328, 2025. e-Pub 2025. PMID: 39724142.
4. Van Den Bent, MJ, French, PJ, Brat, D, Tonn, JC, Touat, M, Ellingson, BM, Young, RJ, Pallud, J, Von Deimling, A, Sahm, F, Figarella-Branger, D, Huang, R, Weller, M, Mellinghoff, IK, Cloughsey, TF, Huse, J, Aldape, K, Reifenberger, G, Youssef, GC, Karschnia, P, Noushmehr, H, Peters, KB, Ducray, F, Preusser, M, Wen, PY. The biological significance of tumor grade, age, enhancement, and extent of resection in IDH-mutant gliomas. Neuro-oncology 26(10):1805-1822, 2024. e-Pub 2024. PMID: 38912846.
5. Hotchkiss, KM, Karschnia, P, Schreck, KC, Geurts, M, Cloughesy, TF, Huse, J, Duke, E, Lathia, JD, Ashley, DM, Nduom, E, Long, GV, Singh, K, Chalmers, AJ, Ahluwalia, MS, Heimberger, AB, Bagley, S, Todo, T, Verhaak, R, Kelly, PD, Hervey-Jumper, S, De Groot, J, Patel, AP, Fecci, PE, Parney, IF, Wykes, V, Watts, C, Burns, TC, Sanai, N, Preusser, M, Tonn, JC, Drummond, K, Platten, M, Das, S, Tanner, K, Vogelbaum, MA, Weller, M, Whittle, J, Berger, M, Khasraw, M. A brave new framework for glioma drug development. The lancet oncology 25(10):e512-e519, 2024. e-Pub 2024. PMID: 39362262.
6. Karschnia, P, Smits, M, Reifenberger, G, Le Rhun, E, Ellingson, BM, Galldiks, N, Kim, MM, Huse, J, Schnell, O, Harter, PN, Mohme, M, Aldape, KD, Baehring, J, Bello, L, Brat, DJ, Cahill, DP, Chung, C, Colman, H, Dietrich, J, Drummond, K, Esquenazi, Y, Gerstner, E, Furtner, J, Garibotto, V, Kaufmann, TJ, Komori, T, Kotecha, R, Liau, LM, Lupo, JM, Minniti, G, Narita, Y, Niyazi, M, Perry, A, Preusser, M, Ruda, R, Sanai, N, Schmidt, NO, Steinbach, JP, Thust, S, Tolboom, N, van der Hoorn, A, van der Vaart, T, Verger, A, Vik-Mo, EO, Watts, C, Westphal, M, Wesseling, P, Young, JS, Von Baumgarten, L, Albert, NL. A framework for standardised tissue sampling and processing during resection of diffuse intracranial glioma. The lancet oncology 24(11):e438-e450, 2023. e-Pub 2023. PMID: 37922934.
7. Whitfield BT, Huse JT. Classification of adult-type diffuse gliomas: Impact of the World Health Organization 2021 update. Brain Pathol 32(4):e13062, 2022. e-Pub 2022. PMID: 35289001.
8. Dharmaiah S, Huse JT. The epigenetic dysfunction underlying malignant glioma pathogenesis. Lab Invest 102(7):682-690, 2022. e-Pub 2022. PMID: 35152274.
9. Brat DJ, Aldape K, Bridge JA, Canoll P, Colman H, Hameed MR, Harris BT, Hattab EM, Huse JT, Jenkins RB, Lopez-Terrada DH, McDonald WC, Rodriguez FJ, Souter LH, Colasacco C, Thomas NE, Yount MH, van den Bent MJ, Perry A. Molecular Biomarker Testing for the Diagnosis of Diffuse Gliomas. Arch Pathol Lab Med 146(5):547-574, 2022. e-Pub 2022. PMID: 35175291.
10. Perez A, Huse JT. The Evolving Classification of Diffuse Gliomas: World Health Organization Updates for 2021. Curr Neurol Neurosci Rep 21(12):67, 2021. e-Pub 2021. PMID: 34817712.
11. Haider AS, van den Bent M, Wen PY, Vogelbaum MA, Chang S, Canoll PD, Horbinski CM, Huse JT. Toward a standard pathological and molecular characterization of recurrent glioma in adults: a Response Assessment in Neuro-Oncology effort. Neuro Oncol 22(4):450-456, 2020. e-Pub 2020. PMID: 31844891.

Other Articles

1. Glitza, IC, Ferguson, SD, Bassett Jr, R, Foster, AP, John, I, Hennegan, TD, Rohlfs, ML, Richard, J, Iqbal, M, Dett, TK, Lacey, C, Jackson, N, Rodgers, TE, Phillips, S, Duncan, S, Haydu, LE, Lin, R, Amaria, RN, Wong, MK, Diab, A, Yee, C, Patel, SP, McQuade, JL, Fischer, G, McCutcheon, IE, O'Brien, BJ, Tummala, S, Debnam, M, Guha-Thakurta, N, Wargo, J, Carapeto, F, Hudgens, CW, Huse, J, Tetzlaff, M, Burton, EM, Tawbi, H, Davies, MA Author Correction. Nature medicine 30(6):1787, 2024. PMID: 38649781.
2. Jahedi, A, Kumar, G, Kannan, L, Agrawal, T, Huse, J, Bhat, KP, Kannan, KS Erratum. PloS one 19(12):e0315099, 2024. PMID: 39625943.
3. Cortés-Ciriano, I, Lee, JK, Xi, R, Jain, D, Jung, YL, Yang, L, Gordenin, D, Klimczak, LJ, Zhang, CZ, Pellman, D, Akdemir, KC, Alvarez, EG, Baez-Ortega, A, Beroukhim, R, Boutros, PC, Bowtell, DD, Brors, B, Burns, KH, Campbell, PJ, Chan, K, Chen, K, Cortés-Ciriano, I, Dueso-Barroso, A, Akbani, R, Akdemir, KC, Aldape, KD, Cao, S, Chakravarty, D, Chen, Y, Czerniak, BA, Eils, R, El-Naggar, AK, Fan, Y, Gershenwald, JE, Han, L, Huse, J, von Kalle, C, Krishnamurthy, S, Langerod, A, Lazar, A, Lichter, P, Mills, GB, Myklebost, O, Sood, AK, Thompson, A, Van Loo, P, Wang, L, Weinstein, JN, Yuan, Y, Zhu, H Author Correction. Nature Genetics 55(6):1076, 2023. PMID: 36944733.
4. Cortés-Ciriano, I, Lee, JK, Xi, R, Jain, D, Jung, YL, Yang, L, Gordenin, D, Klimczak, LJ, Zhang, CZ, Pellman, D, Akdemir, KC, Alvarez, EG, Baez-Ortega, A, Beroukhim, R, Boutros, PC, Bowtell, DD, Brors, B, Burns, KH, Campbell, PJ, Chan, K, Chen, K, Cortés-Ciriano, I, Dueso-Barroso, A, Akbani, R, Akdemir, KC, Aldape, KD, Cao, S, Chakravarty, D, Chen, Y, Czerniak, BA, Eils, R, El-Naggar, AK, Fan, Y, Gershenwald, JE, Han, L, Huse, J, von Kalle, C, Krishnamurthy, S, Langerod, A, Lazar, A, Lichter, P, Mills, GB, Myklebost, O, Sood, AK, Thompson, A, Van Loo, P, Wang, L, Weinstein, JN, Yuan, Y, Zhu, H Author Correction. Nature Genetics 55(6):1076, 2023. PMID: 36944733.
5. Yuan, Y, Ju, YS, Kim, Y, Li, J, Wang, Y, Yoon, CJ, Yang, Y, Martincorena, I, Creighton, CJ, Weinstein, JN, Xu, Y, Han, L, Kim, HL, Nakagawa, H, Park, K, Campbell, PJ, Liang, H, Aaltonen, LA, Abascal, F, Abeshouse, A, Aburatani, H, Adams, DJ, Agrawal, N, Ahn, KS, Ahn, SM, Aikata, H, Akbani, R, Akdemir, KC, Aldape, KD, Cao, S, Chakravarty, D, Chen, Y, Czerniak, BA, Eils, R, El-Naggar, AK, Fan, Y, Gershenwald, JE, Han, L, Huse, J, von Kalle, C, Krishnamurthy, S, Langerod, A, Lazar, A, Lichter, P, Mills, GB, Myklebost, O, Sood, AK, Thompson, A, Van Loo, P, Wang, L Author Correction. Nature Genetics 55(6):1078, 2023. PMID: 36944732.
6. Akdemir, KC, Le, VT, Chandran, S, Li, Y, Verhaak, R, Beroukhim, R, Campbell, PJ, Chin, L, Dixon, JR, Futreal, A, Akdemir, KC, Alvarez, EG, Baez-Ortega, A, Boutros, PC, Bowtell, DD, Brors, B, Burns, KH, Campbell, PJ, Chan, K, Chen, KS, Cortés-Ciriano, I, Dueso-Barroso, A, Dunford, AJ, Akbani, R, Aldape, KD, Cao, S, Chakravarty, D, Chen, Y, Czerniak, BA, Eils, R, El-Naggar, AK, Fan, Y, Gershenwald, JE, Han, L, Huse, J, von Kalle, C, Krishnamurthy, S, Langerod, A, Lazar, A, Li, J, Lichter, P, Mills, GB, Myklebost, O, Sood, AK, Thompson, A, Van Loo, P, Wang, L, Weinstein, JN, Yuan, Y, Zhu, H Author Correction. Nature Genetics 55(6):1079, 2023. PMID: 36944735.
7. Yakneen, S, Waszak, SM, Aminou, B, Bartolome, J, Boroevich, KA, Boyce, R, Brooks, AN, Buchanan, A, Buchhalter, I, Butler, A, Byrne, NJ, Cafferkey, A, Campbell, PJ, Chen, Z, Cho, S, Choi, W, Clapham, P, Davis-Dusenbery, BN, De La Vega, FM, Eils, R, Akbani, R, Akdemir, KC, Cao, S, Chakravarty, D, Chen, K, Chen, Y, Chong, Z, Czerniak, BA, El-Naggar, AK, Fan, Y, Futreal, A, Gershenwald, JE, Han, L, Huse, J, von Kalle, C, Krishnamurthy, S, Lazar, A, Wang, L, Li, J, Liang, H, Lu, Y, Mills, GB, Park, K, Sood, AK, Su, X, Ueno, NT, Wang, L, Wang, W, Weinstein, JN, Yuan, Y Author Correction. Nature biotechnology 41(4):577, 2023. PMID: 36944844.
8. Gerstung, M, Jolly, C, Leshchiner, I, Dentro, SC, Gonzalez, S, Rosebrock, D, Mitchell, TJ, Rubanova, Y, Anur, P, Yu, K, Tarabichi, M, Deshwar, A, Wintersinger, J, Kleinheinz, K, Vázquez-García, I, Haase, K, Jerman, L, Sengupta, S, Macintyre, G, Malikic, S, Donmez, N, Livitz, DG, Cmero, M, Demeulemeester, J, Schumacher, S, Fan, Y, Zhu, H, Wang, W, Van Loo, P, Fan, Y, Akbani, R, Akdemir, KC, Aldape, KD, Cao, S, Chakravarty, D, Chen, Y, Czerniak, BA, Eils, R, El-Naggar, AK, Gershenwald, JE, Han, L, Huse, J, von Kalle, C, Krishnamurthy, S, Lazar, A, Lichter, P, Mills, GB, Sood, AK, Wang, L, Weinstein, JN Author Correction. Nature 614(7948):E42, 2023. PMID: 36697833.
9. Calabrese, C, Davidson, NR, Demircioğlu, D, Fonseca, NA, He, Y, Kahles, A, Lehmann, KV, Liu, F, Shiraishi, Y, Soulette, CM, Urban, L, Calabrese, C, Davidson, NR, Demircioğlu, D, Fonseca, NA, He, Y, Kahles, A, Lehmann, KV, Liu, F, Shiraishi, Y, Soulette, CM, Urban, L, Greger, L, Li, S, Liu, D, Perry, MD, Xiang, Q, Zhang, F, Zhang, J, Bailey, PJ, Erkek, S, Hoadley, KA, Hou, Y, Huska, M, Kilpinen, H, Korbel, JO, Marin, MG, Markowski, J, Chakravarty, D, Chong, Z, El-Naggar, AK, Fan, Y, Gershenwald, JE, Huse, J, von Kalle, C, Lazar, A, Mills, GB, Sood, AK, Van Loo, P, Weinstein, JN Author Correction. Nature 614(7948):E37, 2023. PMID: 36697831.
10. Li, Y, Roberts, ND, Wala, JA, Shapira, O, Schumacher, SE, Kumar, K, Khurana, E, Waszak, S, Korbel, JO, Haber, JE, Imielinski, MB, Akdemir, KC, Alvarez, EG, Baez-Ortega, A, Beroukhim, R, Boutros, PC, Bowtell, DD, Brors, B, Burns, KH, Campbell, PJ, Chan, K, Chen, K, Cortés-Ciriano, I, Dueso-Barroso, A, Dunford, A, Edwards, PA, Estivill, X, Etemadmoghadam, D, Feuerbach, L, Fink, JL, Frenkel-Morgenstern, M, Garsed, DW, Chakravarty, D, Chong, Z, El-Naggar, AK, Fan, Y, Gershenwald, JE, Han, L, Huse, J, von Kalle, C, Krishnamurthy, S, Langerod, A, Lazar, A, Lichter, P, Mills, GB, Park, K, Sood, AK, Thompson, A, Van Loo, P, Weinstein, JN Author Correction. Nature 614(7948):E38, 2023. PMID: 36697835.
11. Alexandrov, LB, Kim, J, Haradhvala, NJ, Huang, MN, Tian Ng, AW, Wu, Y, Boot, A, Covington, KR, Gordenin, DA, Bergstrom, EN, Islam, SM, Lopez-Bigas, N, Klimczak, LJ, McPherson, JR, Morganella, S, Sabarinathan, R, Wheeler, DA, Mustonen, V, Alexandrov, LB, Akbani, R, Akdemir, KC, Cao, S, Chakravarty, D, Chen, K, Chen, Y, Chong, Z, Czerniak, BA, Eils, R, El-Naggar, AK, Fan, Y, Futreal, A, Gershenwald, JE, Han, L, Huse, J, von Kalle, C, Krishnamurthy, S, Lazar, A, Wang, L, Li, J, Liang, H, Lu, Y, Mills, GB, Park, K, Sood, AK, Su, X, Ueno, NT, Wang, W, Weinstein, JN, Yuan, Y, Zhu, H Author Correction. Nature 614(7948):E41, 2023. PMID: 36697836.
12. Aaltonen, LA, Abascal, F, Abeshouse, A, Aburatani, H, Adams, D, Agrawal, N, Ahn, KS, Ahn, SM, Aikata, H, Akbani, R, Akdemir, KC, Al Ahmadie, H, Al-Sedairy, ST, Al-Shahrour, F, Alawi, M, Aldape, KD, Plass, C, Broaddus, R, Langerod, A, Cao, S, Chakravarty, D, Chen, K, Chen, Y, Chong, Z, Czerniak, BA, Eils, R, El-Naggar, AK, Fan, Y, Futreal, A, Gershenwald, JE, Han, L, Huse, J, von Kalle, C, Krishnamurthy, S, Lazar, A, Li, J, Liang, H, Lichter, P, Lu, Y, Mills, GB, Park, K, Sood, AK, Su, X, Thompson, A, Ueno, NT, Van Loo, P, Wang, L, Weinstein, JN, Yuan, Y, Zhu, H Author Correction. Nature 614(7948):E39, 2023. PMID: 36697834.
13. Rubanova, Y, Shi, R, Harrigan, CF, Li, R, Wintersinger, J, Sahin, N, Deshwar, AG, Dentro, SC, Leshchiner, I, Gerstung, M, Jolly, C, Haase, K, Tarabichi, M, Eils, R, Plass, C, Broaddus, R, Cao, S, Wang, W, Van Loo, P, Akbani, R, Akdemir, KC, Aldape, KD, Chakravarty, D, Chen, K, Chen, Y, Chong, Z, Czerniak, BA, El-Naggar, AK, Fan, Y, Futreal, A, Gershenwald, JE, Han, L, Huse, J, von Kalle, C, Krishnamurthy, S, Lazar, A, Li, J, Liang, H, Lichter, P, Lu, Y, Mills, GB, Park, K, Sood, AK, Su, X, Thompson, A, Ueno, NT, Wang, L, Weinstein, JN, Yuan, Y, Zhu, H Author Correction. Nature communications 13(1), 2022. PMID: 36482170.
14. Jiao, W, Atwal, G, Polak, P, Karlic, R, Cuppen, E, Al-Shahrour, F, Atwal, G, Bailey, PJ, Biankin, AV, Boutros, PC, Campbell, PJ, Chang, DK, Cooke, SL, Desphande, V, Faltas, B, Lazar, A, Akbani, R, Akdemir, KC, Aldape, KD, Cao, S, Chakravarty, D, Chen, K, Chen, Y, Chong, Z, Czerniak, BA, Eils, R, El-Naggar, AK, Fan, Y, Futreal, A, Gershenwald, JE, Han, L, Huse, J, von Kalle, C, Krishnamurthy, S, Li, J, Liang, H, Lichter, P, Lu, Y, Mills, GB, Park, K, Sood, AK, Su, X, Thompson, A, Ueno, NT, Van Loo, P, Wang, L, Wang, W, Weinstein, JN, Yuan, Y, Zhu, H Author Correction. Nature communications 13(1), 2022. PMID: 36481665.
15. Sieverling, L, Hong, C, Koser, S, Ginsbach, P, Kleinheinz, K, Hutter, B, Braun, DM, Cortés-Ciriano, I, Xi, R, Kabbe, R, Park, PJ, Eils, R, Schlesner, M, Akdemir, KC, Alvarez, EG, Baez-Ortega, A, Beroukhim, R, Chen, K, Akbani, R, Aldape, KD, Cao, S, Chakravarty, D, Chen, Y, Chong, Z, Czerniak, BA, El-Naggar, AK, Fan, Y, Futreal, A, Gershenwald, JE, Han, L, Huse, J, von Kalle, C, Krishnamurthy, S, Lazar, A, Li, J, Liang, H, Lichter, P, Lu, Y, Mills, GB, Park, K, Sood, AK, Su, X, Thompson, A, Ueno, NT, Van Loo, P, Wang, L, Wang, W, Weinstein, JN, Yuan, Y, Zhu, H Author Correction. Nature communications 13(1), 2022. PMID: 36481818.
16. Zhang, Y, Chen, F, Fonseca, NA, He, Y, Fujita, M, Nakagawa, H, Zhang, Z, Brazma, A, Amin, SB, Awadalla, P, Bailey, PJ, Brazma, A, Brooks, AN, Plass, C, Broaddus, R, Akbani, R, Akdemir, KC, Aldape, KD, Cao, S, Chakravarty, D, Chen, K, Chen, Y, Chong, Z, Czerniak, BA, Eils, R, El-Naggar, AK, Fan, Y, Futreal, A, Gershenwald, JE, Han, L, Huse, J, von Kalle, C, Krishnamurthy, S, Lazar, A, Li, J, Liang, H, Lichter, P, Lu, Y, Mills, GB, Park, K, Sood, AK, Su, X, Thompson, A, Ueno, NT, Van Loo, P, Wang, L, Wang, W, Weinstein, JN, Yuan, Y, Zhu, H Author Correction. Nature communications 13(1), 2022. PMID: 36481652.
17. Cmero, M, Yuan, K, Ong, CS, Schröder, J, Adams, DJ, Anur, P, Beroukhim, R, Boutros, PC, Bowtell, DD, Campbell, PJ, Cao, S, Christie, EL, Cun, Y, Eils, R, Plass, C, Broaddus, R, Deshwar, AG, Fan, Y, Van Loo, P, Wang, W, Akbani, R, Akdemir, KC, Aldape, KD, Chakravarty, D, Chen, K, Chen, Y, Chong, Z, Czerniak, BA, El-Naggar, AK, Futreal, A, Gershenwald, JE, Han, L, Huse, J, von Kalle, C, Krishnamurthy, S, Lazar, A, Li, J, Liang, H, Lichter, P, Lu, Y, Mills, GB, Park, K, Sood, AK, Su, X, Thompson, A, Ueno, NT, Wang, L, Weinstein, JN, Yuan, Y, Zhu, H Author Correction. Nature communications 13(1), 2022. PMID: 36481724.
18. Shuai, S, Abascal, F, Amin, S, Bader, GD, Bandopadhayay, P, Barenboim, J, Beroukhim, R, Bertl, J, Boroevich, KA, Brunak, S, Campbell, PJ, Carlevaro-Fita, J, Chakravarty, D, Chan, CY, Chen, K, Choi, JK, Park, K, Akbani, R, Akdemir, KC, Aldape, KD, Cao, S, Chakravarty, D, Chen, Y, Chong, Z, Czerniak, BA, Eils, R, El-Naggar, AK, Fan, Y, Futreal, A, Gershenwald, JE, Han, L, Huse, J, von Kalle, C, Krishnamurthy, S, Lazar, A, Li, J, Liang, H, Lichter, P, Lu, Y, Mills, GB, Sood, AK, Su, X, Thompson, A, Ueno, NT, Van Loo, P, Wang, L, Wang, W, Weinstein, JN, Yuan, Y, Zhu, H Author Correction. Nature communications 13(1), 2022. PMID: 36481739.
19. Bhandari, V, Li, CH, Bristow, RG, Boutros, PC, Aaltonen, LA, Abascal, F, Abeshouse, A, Aburatani, H, Adams, D, Agrawal, N, Ahn, KS, Ahn, SM, Aikata, H, Akbani, R, Akdemir, KC, Plass, C, Broaddus, R, Aldape, KD, Cao, S, Chakravarty, D, Chen, K, Chen, Y, Chong, Z, Czerniak, BA, Eils, R, El-Naggar, AK, Fan, Y, Futreal, A, Gershenwald, JE, Han, L, Huse, J, von Kalle, C, Krishnamurthy, S, Lazar, A, Li, J, Liang, H, Lichter, P, Lu, Y, Mills, GB, Park, K, Sood, AK, Su, X, Thompson, A, Ueno, NT, Van Loo, P, Wang, L, Wang, W, Weinstein, JN, Yuan, Y, Zhu, H Author Correction. Nature communications 13(1), 2022. PMID: 36481612.
20. Reyna, MA, Haan, D, Paczkowska, M, Verbeke, LP, Vazquez, M, Kahraman, A, Pulido-Tamayo, S, Barenboim, J, Wadi, L, Dhingra, P, Shrestha, R, Getz, G, Lawrence, MS, Pedersen, JS, Chakravarty, D, Chen, K, Park, K, Akbani, R, Akdemir, KC, Aldape, KD, Cao, S, Chakravarty, D, Chen, Y, Chong, Z, Czerniak, BA, Eils, R, El-Naggar, AK, Fan, Y, Futreal, A, Gershenwald, JE, Han, L, Huse, J, von Kalle, C, Krishnamurthy, S, Lazar, A, Li, J, Liang, H, Lichter, P, Lu, Y, Mills, GB, Sood, AK, Su, X, Thompson, A, Ueno, NT, Van Loo, P, Wang, L, Wang, W, Weinstein, JN, Yuan, Y, Zhu, H Author Correction. Nature communications 13(1), 2022. PMID: 36481610.
21. Walsh, KM, Neff, C, Bondy, ML, Kruchko, C, Huse, J, Amos, CI, Barnholtz-Sloan, J, Ostrom, QT Corrigendum. Neuro-oncology 24(12):2221, 2022. PMID: 36346327.
22. Paczkowska, M, Barenboim, J, Sintupisut, N, Fox, NS, Zhu, H, Abd-Rabbo, D, Mee, MW, Boutros, PC, Abascal, F, Amin, S, Bader, GD, Beroukhim, R, Bertl, J, Boroevich, KA, Chakravarty, D, Chen, K, Park, K, Akbani, R, Akdemir, KC, Aldape, KD, Cao, S, Chakravarty, D, Chen, Y, Chong, Z, Czerniak, BA, Eils, R, El-Naggar, AK, Fan, Y, Futreal, A, Gershenwald, JE, Han, L, Huse, J, von Kalle, C, Krishnamurthy, S, Lazar, A, Li, J, Liang, H, Lichter, P, Lu, Y, Mills, GB, Sood, AK, Su, X, Thompson, A, Ueno, NT, Van Loo, P, Wang, L, Wang, W, Weinstein, JN, Yuan, Y, Zhu, H Author Correction. Nature communications 13(1), 2022. PMID: 36481658.

Editorials

1. Huse, J. Advancing intraoperative diagnostics, one (or rather three) mutations at a time. Neuro-oncology 27(12):3174-3175, 2025. PMID: 41092310.
2. Huse, JT. TERT promoter mutation designates biologically aggressive primary glioblastoma. Neuro-Oncol(17):5-6, 2015.
3. Huse, JT, Aldape, KD. CMV and glioma-are we there yet?. Neuro-Oncol(16):1433-1434, 2014.

Book Chapters

1. Ballester, LY, Huse, JT. Cancer of the Central Nervous System: Pathology and Molecular Genetics. In: Bradley’s Neurology in Clinical Practice. 8th, Ch. 72, 2017.
2. Diemling V, A, Huse, JT, Yan, H, Brat, DJ, Reifenberger, G, Kleihues, P, Berger, MS, Weller, M, Nakazato, Y, Burger, PC, Ellison, DW, Louis, DN. Anaplastic astrocytoma, IDH-mutant. In: WHO Classification of Tumours of the Central Nervous System. Revised 4th Edition, 2016.
3. Huse, JT, Jansen, M, Perry, A, Heffner, RR, LOuis, DN. Cancer of the Central Nervous System: Pathology and Molecular Genetics. In: Bradley's Neuorology in Clinical Practice. 7th Edition, 5-6, 2016.
4. Rosenblum, MK, Nakazato Y, Matsutani, M, Ichimura, K, Leuschner, Huse I, JT. Germ Cell Tumors. In: WHO Classification of Tumors of the Central Nervous System. Revised 4th Edition, 2016.
5. Diemling, A, Huse, JT, Yan, H, Brat, DJ, Reifenberger, G, Kleihues, P, Berger, MS, Weller, M, Nakazato, Y, Burger, PC, Ellison, DW, Louis, DN. Diffuse astrocytoma, IDH-mutant. In: WHO Classification of Tumours of the Central Nervous System. Revised 4th Edition, 2016.

Letters to the Editor

1. Beck, J, Mazcko, C, Belluco, S, Bitar, M, Brat, DJ, Bush, JW, Chkheidze, R, Corps, K, Frank, C, Giannini, C, Horbinski, C, Huse, J, Koehler, JW, Miller, AD, Miller, CR, O'Sullivan, MG, Phillips, JJ, Rissi, DR, Schott, CR, Stemmer-Rachamimov, AO, Yip, S, LeBlanc, A. Comparative pathology boards facilitate the translation of knowledge between canine and human cancer patients. Brain Pathology 35, 2025.
2. Gubbiotti, M, Weinberg, JS, Weathers, S, Dasgupta, P, Tom, MC, Aldape, K, Quezado, M, Abdullaev, Z, Huse, J, Ballester, L. An incidental finding of a high-grade glioma with pleomorphic and pseudopapillary features (HPAP) with PBRM1 mutation. Journal of neuropathology and experimental neurology 83: 139-141, 2024.